id author title date pages extension mime words sentences flesch summary cache txt cord-257191-u5xnmsv8 Farshi, Esmaeil Investigation of immune cells on elimination of pulmonary‐Infected COVID‐19 and important role of innate immunity, phagocytes 2020-09-18 .txt text/plain 2540 128 53 [4] [5] [6] [7] [8] Lethal disease in BALB/c mice infected with a mouse-adapted strain of SARS-CoV, MA15, showed a lack of activation of innate immune response, resulting in a barely detectable antivirus T cell response. 8 On the other hand, aged BALB/c mice that were infected with a human clinical isolate of SARS-CoV (Urbani strain) successfully eliminated the invasive virus within 1 week post-infection; these mice exhibited high and prolonged levels of viral replication, signs consistent with clinical symptoms, and pathologic changes in the lung resembling those seen in elderly SARS patients. In this study, we attempted to identify the types of immune cells that contribute to clearing COVID-19 during the acute phase of the infection in mice models plus human. Cellular immune responses to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in senescent BALB/c mice: CD4+ T cells are important in control of SARS-CoV infection ./cache/cord-257191-u5xnmsv8.txt ./txt/cord-257191-u5xnmsv8.txt