id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-256233-k9hdq3z8	Lipsky, Martin S.	Men and COVID-19: A Pathophysiologic Review	2020-09-16		.txt	text/plain	4620	233	47	The plausible theories underlying these observations include sex-related differences in angiotensin-converting enzyme 2 receptors, immune function, hormones, habits, and coinfection rates.In this review we examine these factors and explore the rationale as to how each may impact COVID-19. Epidemiological evidence from influenza outbreaks and pandemics also reveals a higher morbidity and mortality for menthan that for women in some age groups (Klein et al., 2012) .In animal studies, male animals have poorer immune responses when exposed to the coronavirus and experience more damage to their lungs (Vermillion et al., 2018) .For both SARS and the MERS coronavirus outbreaks, men fared worse than women did. A recent German study found that that critically ill male COVID-19 patients suffer from severe testosterone and dihydrotestosterone deficiencies and concluded that androgens are required to mount a strong antiviral immune response to combat infection in men (Schroeder et al., 2020) .	./cache/cord-256233-k9hdq3z8.txt	./txt/cord-256233-k9hdq3z8.txt