id author title date pages extension mime words sentences flesch summary cache txt cord-254120-1q8tqeg7 Iannone, Primiano The need of health policy perspective to protect Healthcare Workers during COVID-19 pandemic. A GRADE rapid review on the N95 respirators effectiveness. 2020-04-11 .txt text/plain 3240 207 47 The WHO, ECDC and CDC have issued conflicting guidelines on the use of respiratory filters (N95) by HCWs. Methods We searched PubMed, Embase and The Cochrane Library from the inception to March 21, 2020 to identify randomized controlled trials (RCTs) comparing N95 respirators versus surgical masks for prevention of COVID-19 or any other respiratory infection among HCWs. The grading of recommendations, assessment, development, and evaluation (GRADE) was used to evaluate the quality of evidence. However, wearing N95 respirators can prevent 73 more (95% CI 46-91) clinical respiratory infections per 1000 HCWs compared to surgical masks (2 RCTs; 2594 patients; low quality of evidence). We therefore conducted a systematic review aimed at assessing the efficacy of N95 respirators versus surgical masks for the prevention of respiratory tract infections transmission among HCWs. The evidence from the review can then be used for the development of an appropriate GRADE framework for public health policy guidelines. ./cache/cord-254120-1q8tqeg7.txt ./txt/cord-254120-1q8tqeg7.txt