id author title date pages extension mime words sentences flesch summary cache txt cord-253990-m75xwrz9 Wang, Zhiguo Covid‐19: From structure to therapeutic targeting in studying approved drugs and local DNA vaccination 2020-10-29 .txt text/plain 1125 62 48 The current lack of specific and effective therapies for the COVID-19, and the continuous spread of coronavirus SARS-CoV-2 across many parts of the world, represent one of the major challenges in controlling the disease severity, keeping to pose a huge threat to the global health. The current lack of specific and effective therapies for the COVID-19, and the continuous spread of coronavirus SARS-CoV-2 across many parts of the world, represents one of the major challenges in controlling the disease severity and consequences, posing a huge threat to the global health. In this article, we highlight several previously approved drugs for potential effect on combating SARS-CoV-2 coronavirus infection, and modulating pulmonary inflammation and immune response. Despite unprecedented efforts to contain the virus spread and prevent infection, SARS-CoV-2 pneumonitis can still rapidly strike to incapacitate the lung causing severe acute respiratory distress syndrome (ARDS), resulting in severe disease aftermath and sometimes death. ./cache/cord-253990-m75xwrz9.txt ./txt/cord-253990-m75xwrz9.txt