id author title date pages extension mime words sentences flesch summary cache txt cord-253331-z443e8lk Stanhope, Michael J. Evidence from the evolutionary analysis of nucleotide sequences for a recombinant history of SARS-CoV 2004-03-31 .txt text/plain 2564 105 44 Based on evolutionary analyses of coronavirus DNA sequences, encompassing an approximately 13kb stretch of the SARS-TOR2 genome, we provide evidence that SARS-CoV has a recombinant history with lineages of types I and III coronavirus. Our results act to both corroborate and extend their findings, adding further support to the idea that SARS has had a recombinant history involving different coronavirus lineages and suggest the possibility that the genome could have arisen through a combination of host jumping and recombination events in a manner analogous to previous outbreaks of influenzae (Gregory et al., 2003; Zhou et al., 1999) . Our results indicate that SARS-CoV recombined with a member of the group III lineage, suggesting that an avian coronavirus was involved, a further point of general agreement between our results and that of Rest and Mindell (2003) . ./cache/cord-253331-z443e8lk.txt ./txt/cord-253331-z443e8lk.txt