id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252234-3txk22yj	Kaniyala Melanthota, Sindhoora	Elucidating the microscopic and computational techniques to study the structure and pathology of SARS‐CoVs	2020-08-07		.txt	text/plain	3988	226	50	Coronavirus replication is initiated with the binding of virion particles to the receptors of the cells, further directing the translation of the viral genome in the cytoplasm and synthesis of membrane-bound proteins. Previous studies have shown the use of a scanning electron microscope (SEM) for obtaining surface information and TEM for revealing inner components of the SARS-CoV particle. Table 1 compares various microscopy techniques for understanding the structure of SARS-CoV and its effect in host cells. The E6 cell lines were subjected to thin-layer electron microscopy and the images revealed typical coronavirus particles within the rough endoplasmic reticulum, specifically in cisternae, as well as in vesicles and several large clusters of extracellular particles were found attached to the surface of the plasma membrane. Apart from studying how the virus enters the cell, immunofluorescence was also used to investigate antibody response to the SARS-CoV and use it as an efficient detection method.	./cache/cord-252234-3txk22yj.txt	./txt/cord-252234-3txk22yj.txt