id author title date pages extension mime words sentences flesch summary cache txt cord-218886-lqme2j8n Asghari, Aref Fast Accurate Point of Care COVID-19 Pandemic Diagnosis Enabled Through Advanced Lab-on-a-Chip Optical Biosensors: Opportunities and Challenges 2020-08-01 .txt text/plain 6422 287 46 Primarily, an optical biosensor translates the capture of the target analyte in a measurable alteration of a light property, such as refractive index (RI), intensity or resonance shift, through different methods such as resonators and interferometers ( Fig. 2 ). The sensing transduction signals in Optical label-free biosensing platform functions based on miniscule changes in refractive index resulting from the attachment of biomolecules to the immobilized bioreceptors. On the other hand, by simply depositing a gold layer, the device concept can be used for a surface plasmon resonance, which can improve the LOD even further 71 In order to maximize the sensitivity of the waveguide-based biosensor, the speed of light can be reduced even further. Graphene unique electrical properties has also been exploited effectively to develop different transistor based label-free biosensors including COVID-19 detection system 39 (fig 18.a) . ./cache/cord-218886-lqme2j8n.txt ./txt/cord-218886-lqme2j8n.txt