id author title date pages extension mime words sentences flesch summary cache txt cord-196608-k4f79dr4 Saha, Sovan Computational modeling of Human-nCoV protein-protein interaction network 2020-05-05 .txt text/plain 4387 262 51 Our developed computational model of nCoV-Human PPIN contains high quality interactions (HQI) and proteins identified by Fuzzy affinity thresholding and spreadability index validated by SIS model respectively. With the gradual progress of the work, it has been observed that the selected human spreader nodes, identified by our proposed model, emerge as the potential protein targets of the FDA approved drugs for COVID-19. Target proteins of the potential FDA drugs for COVID-19 are found to overlap with the spreader nodes of the proposed computational nCoV-Human protein interaction model. Target proteins of seven potential FDA drugs: Lopinavir 30 , Ritonavir 31 , Hydroxychloroquine 32, 33 , Azithromycin 33 , Remdesivir 34-36 , Favipiravir 37, 38 and Darunavir 39 for COVID-19 as mentioned in the DrugBank white paper 26 overlap with the spreader nodes of the proposed in silico nCoV-Human protein interaction model (see Figure 5 ). ./cache/cord-196608-k4f79dr4.txt ./txt/cord-196608-k4f79dr4.txt