id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-146679-g7qioapl	Jaimes, Javier A.	Structural modeling of 2019-novel coronavirus (nCoV) spike protein reveals a proteolytically-sensitive activation loop as a distinguishing feature compared to SARS-CoV and related SARS-like coronaviruses	2020-02-14		.txt	text/plain	3652	181	55	title: Structural modeling of 2019-novel coronavirus (nCoV) spike protein reveals a proteolytically-sensitive activation loop as a distinguishing feature compared to SARS-CoV and related SARS-like coronaviruses To obtain an initial assessment of shared and/or specific features of the 2019-nCoV spike (S) envelope glycoprotein, a protein sequence alignment was performed to compare the sequence of the Wuhan-Hu-1 strain of the novel coronavirus with that of the closely related human SARS-CoV S strain Tor2 sequence ( Supplementary Fig. 1 ). The relatively high degree of sequence identity for the RBD is consistent with the view that 2019-nCoV, like SARS-CoV, may use ACE2 as its host cell receptor, The composition of residues found at the two known coronavirus S cleavage sites was performed using alignment data ( Fig. 2B and C).	./cache/cord-146679-g7qioapl.txt	./txt/cord-146679-g7qioapl.txt