id author title date pages extension mime words sentences flesch summary cache txt cord-104507-xx7t26rl Safari, Saeid Extracorporeal Hemoperfusion as a Potential Therapeutic Option for Severe COVID-19 patients; a Narrative Review 2020-08-22 .txt text/plain 3425 173 31 Based on previous experience of blood purification to treat cytokine storm syndrome (CSS) in severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), here we aimed to review the current literature on extracorporeal hemoperfusion as a potential therapeutic option for CSS-associated conditions, with a focus on severe COVID-19. To date, various centers in different countries including Italy, China, USA, Germany, and Iran have reported or are investigating the beneficial effects of different hemoperfusion systems, including HA380/HA330 cartridges, CytoSorb, and polymyxin B immobilized fiber column in treatment of critically-ill COVID-19 patients. To date, a large number of experimental and clinical data, mostly from case reports and case series, have introduced CytoSorb as an effective rescue therapy for removal of inflammatory cytokines and achievement of hemodynamic stabilization in critically ill patients with septic shock and kidney failure (47) (48) (49) . ./cache/cord-104507-xx7t26rl.txt ./txt/cord-104507-xx7t26rl.txt