id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-035274-hu8zshq8	Jadali, Zohreh	Neurologic manifestations of COVID-19: what can we learn from other coronaviruses	2020-11-11		.txt	text/plain	703	57	43	Like other coronaviruses, SARS-CoV-2 is neurotropic and may spread to the nervous system via similar mechanisms. Neurotropic and neuroinvasive properties of SARS-CoV-2 are supported by several observations including the presence of virus particles in the cerebrospinal fluid of patients with significant nervous system symptoms [3] . Currently, it is difficult to distinguish whether neurological complications of COVID-19 are a consequence of direct or indirect effects of viral infection. Another mechanism relies on blood circulation and angiotensin-converting enzyme 2 (ACE2) receptors that are expressed on glial cells, neurons, and capillary endothelium and are involved in virus entry [4] . Molecular mimicry that could be associated with the development of autoimmunity is another mechanism by which SARS-CoV-2 may trigger an immune response against nervous system-specific proteins [5] . Abbreviations SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; ACE2: Angiotensin-converting enzyme 2 COVID-19 and SARS-Cov-2 infection: pathophysiology and clinical effects on the nervous system The author(s) read and approved the final manuscript.	./cache/cord-035274-hu8zshq8.txt	./txt/cord-035274-hu8zshq8.txt