id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-035157-97tfcgvq	Panchin, Alexander Y.	Excessive G–U transversions in novel allele variants in SARS-CoV-2 genomes	2020-07-28		.txt	text/plain	2803	196	57	RESULTS: We found a 9-fold excess of G–U transversions among SARS-CoV-2 mutations over relative substitution frequencies between SARS-CoV-2 and a close relative coronavirus from bats (RaTG13). SARS-CoV-2 is closely related to the bat coronavirus RaTG13 with around 96% whole genome nucleotide sequence identity . We compared the relative frequencies of single nucleotide variations (which we will refer to as mutations) in SARS-CoV-2 with the relative frequencies of substitutions that it acquired since the divergence with its last common ancestor with a closely related coronavirus from bats RaTG13. On the other hand, the substitution profile of SARS-CoV-2 turned out to be quite similar to that of the other coronaviruses, lending further support to existing scenarios of its natural origin (Andersen et al., 2020) and suggesting that the changes in SARS-CoV-2 mutation frequencies have accompanied its transition to human hosts.	./cache/cord-035157-97tfcgvq.txt	./txt/cord-035157-97tfcgvq.txt