id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-023888-w2sbyfy2	Beniac, Daniel R.	Structural Molecular Insights into SARS Coronavirus Cellular Attachment, Entry and Morphogenesis	2009-07-22		.txt	text/plain	4349	238	57	Receptor binding results in structural changes that have been observed in the spike molecule, and these appear to be the initial step in viral membrane fusion. However, despite the size differences, the SARS-CoV spike performs the same fundamental task in viral entry to the host cell as other smaller type 1 viral fusion proteins, such as the influenza hemagglutinin (HA) (~220 kD per trimer). This structural data has been modeled into a scheme to propose a mechanism for SARS-CoV spike-mediated membrane fusion (Figs. Our cryo-EM results show that it is possible for the spike to attach to three ACE2 receptors at once; this may serve to hold on to the host membrane like a tripod so as to accurately orientate the fusion core ( Fig. 3.7) .	./cache/cord-023888-w2sbyfy2.txt	./txt/cord-023888-w2sbyfy2.txt