id author title date pages extension mime words sentences flesch summary cache txt cord-009295-4c0zwhdh Bal, A. Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino acid deletion in nsp2 (Asp268del) 2020-03-28 .txt text/plain 1253 73 56 title: Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino acid deletion in nsp2 (Asp268del) The phylogenetic analysis using the 571 WGS of SARS-CoV-2 publicly available (as of March 17th 2020) found that this sequence clustered with a sequence (EPI_-ISL_408488) collected in Jiangsu, China, on January 19th, suggesting a separate introduction from Asia (Fig. 1) . Compared to the reference SARS-CoV-2 sequence, a three-nucleotide deletion in open reading frame 1a (ORF1a) at positions 1607e1609 was identified. Letter to the Editor / Clinical Microbiology and Infection xxx (xxxx) xxx SARS-CoV-2 sequences were not further compared between the two patients due to largely incomplete coverage of the SARS-CoV-2 genome in sample #1. Despite low viral loads, the mNGS workflow used herein allowed us to characterize the wholegenome sequences of SARS-CoV-2 isolated from an asymptomatic patient in two clinical samples collected 1 day apart. ./cache/cord-009295-4c0zwhdh.txt ./txt/cord-009295-4c0zwhdh.txt