id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006890-81wv1s33	Viret, Jean-Francois	Development of a SARS vaccine: an industrial perspective on the global race against a global disease	2014-01-09		.txt	text/plain	2069	78	38	The high profile of SARS in the international news media contributed to early public disease awareness but also caused fear in both affected and unaffected populations, placing additional political and economic pressure on authorities to act on the threat despite of an insufficient basis for informed decisions. Once the global scale of the outbreak became fully apparent, the scientific community, supported by the WHO, committed to '...the development of a vaccine against the pathogen is severely impeded by the current fragmentary information on viral pathogenicity and the lack of adequate animal models and correlates of protection in humans.' an unparalleled collaborative effort. More specifically, in spite of the fortunate capability to propagate the SARS-CoV on a well-accepted cell substrate (VERO), the development of a vaccine against the pathogen is severely impeded by the current fragmentary information on viral pathogenicity and the lack of adequate animal models of persistent infection and correlates of protection in humans.	./cache/cord-006890-81wv1s33.txt	./txt/cord-006890-81wv1s33.txt