id sid tid token lemma pos cord-001207-yjaiybwf 1 1 key key JJ cord-001207-yjaiybwf 1 2 : : : cord-001207-yjaiybwf 1 3 cord-001207-yjaiybwf cord-001207-yjaiybwf NFP cord-001207-yjaiybwf 2 1 authors author NNS cord-001207-yjaiybwf 2 2 : : : cord-001207-yjaiybwf 2 3 Sachsenröder Sachsenröder NNP cord-001207-yjaiybwf 2 4 , , , cord-001207-yjaiybwf 2 5 Jana Jana NNP cord-001207-yjaiybwf 2 6 ; ; : cord-001207-yjaiybwf 2 7 Twardziok Twardziok NNP cord-001207-yjaiybwf 2 8 , , , cord-001207-yjaiybwf 2 9 Sven Sven NNP cord-001207-yjaiybwf 2 10 O. O. NNP cord-001207-yjaiybwf 2 11 ; ; : cord-001207-yjaiybwf 2 12 Scheuch Scheuch NNP cord-001207-yjaiybwf 2 13 , , , cord-001207-yjaiybwf 2 14 Matthias Matthias NNP cord-001207-yjaiybwf 2 15 ; ; : cord-001207-yjaiybwf 2 16 Johne Johne NNP cord-001207-yjaiybwf 2 17 , , , cord-001207-yjaiybwf 2 18 Reimar Reimar NNP cord-001207-yjaiybwf 2 19 title title NN cord-001207-yjaiybwf 2 20 : : : cord-001207-yjaiybwf 3 1 The the DT cord-001207-yjaiybwf 3 2 General General NNP cord-001207-yjaiybwf 3 3 Composition Composition NNP cord-001207-yjaiybwf 3 4 of of IN cord-001207-yjaiybwf 3 5 the the DT cord-001207-yjaiybwf 3 6 Faecal Faecal NNP cord-001207-yjaiybwf 3 7 Virome Virome NNP cord-001207-yjaiybwf 3 8 of of IN cord-001207-yjaiybwf 3 9 Pigs Pigs NNPS cord-001207-yjaiybwf 3 10 Depends depend VBZ cord-001207-yjaiybwf 3 11 on on IN cord-001207-yjaiybwf 3 12 Age Age NNP cord-001207-yjaiybwf 3 13 , , , cord-001207-yjaiybwf 3 14 but but CC cord-001207-yjaiybwf 3 15 Not not RB cord-001207-yjaiybwf 3 16 on on IN cord-001207-yjaiybwf 3 17 Feeding feed VBG cord-001207-yjaiybwf 3 18 with with IN cord-001207-yjaiybwf 3 19 a a DT cord-001207-yjaiybwf 3 20 Probiotic probiotic JJ cord-001207-yjaiybwf 3 21 Bacterium bacterium NN cord-001207-yjaiybwf 3 22 date date NN cord-001207-yjaiybwf 4 1 : : : cord-001207-yjaiybwf 4 2 2014 2014 CD cord-001207-yjaiybwf 4 3 - - HYPH cord-001207-yjaiybwf 4 4 02 02 CD cord-001207-yjaiybwf 4 5 - - SYM cord-001207-yjaiybwf 4 6 19 19 CD cord-001207-yjaiybwf 4 7 journal journal NN cord-001207-yjaiybwf 4 8 : : : cord-001207-yjaiybwf 5 1 PLoS PLoS NNP cord-001207-yjaiybwf 5 2 One one CD cord-001207-yjaiybwf 5 3 DOI DOI NNP cord-001207-yjaiybwf 5 4 : : : cord-001207-yjaiybwf 5 5 10.1371 10.1371 CD cord-001207-yjaiybwf 5 6 / / SYM cord-001207-yjaiybwf 5 7 journal.pone.0088888 journal.pone.0088888 NN cord-001207-yjaiybwf 5 8 sha sha NNP cord-001207-yjaiybwf 5 9 : : : cord-001207-yjaiybwf 5 10 ade1a8f088544b34547d3f9608805c969c9f189f ade1a8f088544b34547d3f9608805c969c9f189f NNP cord-001207-yjaiybwf 5 11 doc_id doc_id CD cord-001207-yjaiybwf 5 12 : : : cord-001207-yjaiybwf 5 13 1207 1207 CD cord-001207-yjaiybwf 5 14 cord_uid cord_uid NN cord-001207-yjaiybwf 5 15 : : : cord-001207-yjaiybwf 6 1 yjaiybwf yjaiybwf NNP cord-001207-yjaiybwf 6 2 BACKGROUND BACKGROUND NNP cord-001207-yjaiybwf 6 3 : : : cord-001207-yjaiybwf 7 1 The the DT cord-001207-yjaiybwf 7 2 pig pig NN cord-001207-yjaiybwf 7 3 faecal faecal JJ cord-001207-yjaiybwf 7 4 virome virome NNP cord-001207-yjaiybwf 7 5 , , , cord-001207-yjaiybwf 7 6 which which WDT cord-001207-yjaiybwf 7 7 comprises comprise VBZ cord-001207-yjaiybwf 7 8 the the DT cord-001207-yjaiybwf 7 9 community community NN cord-001207-yjaiybwf 7 10 of of IN cord-001207-yjaiybwf 7 11 viruses virus NNS cord-001207-yjaiybwf 7 12 present present JJ cord-001207-yjaiybwf 7 13 in in IN cord-001207-yjaiybwf 7 14 pig pig NN cord-001207-yjaiybwf 7 15 faeces faece NNS cord-001207-yjaiybwf 7 16 , , , cord-001207-yjaiybwf 7 17 is be VBZ cord-001207-yjaiybwf 7 18 complex complex JJ cord-001207-yjaiybwf 7 19 and and CC cord-001207-yjaiybwf 7 20 consists consist VBZ cord-001207-yjaiybwf 7 21 of of IN cord-001207-yjaiybwf 7 22 pig pig NN cord-001207-yjaiybwf 7 23 viruses virus NNS cord-001207-yjaiybwf 7 24 , , , cord-001207-yjaiybwf 7 25 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 7 26 , , , cord-001207-yjaiybwf 7 27 transiently transiently RB cord-001207-yjaiybwf 7 28 passaged passage VBD cord-001207-yjaiybwf 7 29 plant plant NN cord-001207-yjaiybwf 7 30 viruses virus NNS cord-001207-yjaiybwf 7 31 and and CC cord-001207-yjaiybwf 7 32 other other JJ cord-001207-yjaiybwf 7 33 minor minor JJ cord-001207-yjaiybwf 7 34 virus virus NN cord-001207-yjaiybwf 7 35 species specie NNS cord-001207-yjaiybwf 7 36 . . . cord-001207-yjaiybwf 8 1 Only only RB cord-001207-yjaiybwf 8 2 little little JJ cord-001207-yjaiybwf 8 3 is be VBZ cord-001207-yjaiybwf 8 4 known know VBN cord-001207-yjaiybwf 8 5 about about IN cord-001207-yjaiybwf 8 6 factors factor NNS cord-001207-yjaiybwf 8 7 influencing influence VBG cord-001207-yjaiybwf 8 8 its -PRON- PRP$ cord-001207-yjaiybwf 8 9 general general JJ cord-001207-yjaiybwf 8 10 composition composition NN cord-001207-yjaiybwf 8 11 . . . cord-001207-yjaiybwf 9 1 Here here RB cord-001207-yjaiybwf 9 2 , , , cord-001207-yjaiybwf 9 3 the the DT cord-001207-yjaiybwf 9 4 effect effect NN cord-001207-yjaiybwf 9 5 of of IN cord-001207-yjaiybwf 9 6 the the DT cord-001207-yjaiybwf 9 7 probiotic probiotic JJ cord-001207-yjaiybwf 9 8 bacterium bacterium NN cord-001207-yjaiybwf 9 9 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 9 10 faecium faecium NN cord-001207-yjaiybwf 9 11 ( ( -LRB- cord-001207-yjaiybwf 9 12 E. E. NNP cord-001207-yjaiybwf 9 13 faecium faecium NNP cord-001207-yjaiybwf 9 14 ) ) -RRB- cord-001207-yjaiybwf 9 15 NCIMB NCIMB NNP cord-001207-yjaiybwf 9 16 10415 10415 CD cord-001207-yjaiybwf 9 17 on on IN cord-001207-yjaiybwf 9 18 the the DT cord-001207-yjaiybwf 9 19 pig pig NN cord-001207-yjaiybwf 9 20 faecal faecal JJ cord-001207-yjaiybwf 9 21 virome virome NNP cord-001207-yjaiybwf 9 22 composition composition NN cord-001207-yjaiybwf 9 23 was be VBD cord-001207-yjaiybwf 9 24 analysed analyse VBN cord-001207-yjaiybwf 9 25 in in IN cord-001207-yjaiybwf 9 26 a a DT cord-001207-yjaiybwf 9 27 pig pig NN cord-001207-yjaiybwf 9 28 feeding feed VBG cord-001207-yjaiybwf 9 29 trial trial NN cord-001207-yjaiybwf 9 30 with with IN cord-001207-yjaiybwf 9 31 sows sow NNS cord-001207-yjaiybwf 9 32 and and CC cord-001207-yjaiybwf 9 33 their -PRON- PRP$ cord-001207-yjaiybwf 9 34 piglets piglet NNS cord-001207-yjaiybwf 9 35 , , , cord-001207-yjaiybwf 9 36 which which WDT cord-001207-yjaiybwf 9 37 received receive VBD cord-001207-yjaiybwf 9 38 either either CC cord-001207-yjaiybwf 9 39 the the DT cord-001207-yjaiybwf 9 40 probiotic probiotic JJ cord-001207-yjaiybwf 9 41 bacterium bacterium NN cord-001207-yjaiybwf 9 42 or or CC cord-001207-yjaiybwf 9 43 not not RB cord-001207-yjaiybwf 9 44 . . . cord-001207-yjaiybwf 10 1 RESULTS result NNS cord-001207-yjaiybwf 10 2 : : : cord-001207-yjaiybwf 11 1 From from IN cord-001207-yjaiybwf 11 2 8 8 CD cord-001207-yjaiybwf 11 3 pooled pooled JJ cord-001207-yjaiybwf 11 4 faecal faecal JJ cord-001207-yjaiybwf 11 5 samples sample NNS cord-001207-yjaiybwf 11 6 derived derive VBN cord-001207-yjaiybwf 11 7 from from IN cord-001207-yjaiybwf 11 8 the the DT cord-001207-yjaiybwf 11 9 feeding feeding NN cord-001207-yjaiybwf 11 10 trial trial NN cord-001207-yjaiybwf 11 11 , , , cord-001207-yjaiybwf 11 12 DNA DNA NNP cord-001207-yjaiybwf 11 13 and and CC cord-001207-yjaiybwf 11 14 RNA RNA NNP cord-001207-yjaiybwf 11 15 virus virus NN cord-001207-yjaiybwf 11 16 particles particle NNS cord-001207-yjaiybwf 11 17 were be VBD cord-001207-yjaiybwf 11 18 prepared prepare VBN cord-001207-yjaiybwf 11 19 and and CC cord-001207-yjaiybwf 11 20 subjected subject VBN cord-001207-yjaiybwf 11 21 to to IN cord-001207-yjaiybwf 11 22 process process NN cord-001207-yjaiybwf 11 23 - - HYPH cord-001207-yjaiybwf 11 24 controlled control VBN cord-001207-yjaiybwf 11 25 Next Next NNP cord-001207-yjaiybwf 11 26 Generation Generation NNP cord-001207-yjaiybwf 11 27 Sequencing Sequencing NNP cord-001207-yjaiybwf 11 28 resulting result VBG cord-001207-yjaiybwf 11 29 in in IN cord-001207-yjaiybwf 11 30 390,650 390,650 CD cord-001207-yjaiybwf 11 31 sequence sequence NN cord-001207-yjaiybwf 11 32 reads read VBZ cord-001207-yjaiybwf 11 33 . . . cord-001207-yjaiybwf 12 1 In in IN cord-001207-yjaiybwf 12 2 average average JJ cord-001207-yjaiybwf 12 3 , , , cord-001207-yjaiybwf 12 4 14 14 CD cord-001207-yjaiybwf 12 5 % % NN cord-001207-yjaiybwf 12 6 of of IN cord-001207-yjaiybwf 12 7 the the DT cord-001207-yjaiybwf 12 8 reads read NNS cord-001207-yjaiybwf 12 9 showed show VBD cord-001207-yjaiybwf 12 10 significant significant JJ cord-001207-yjaiybwf 12 11 sequence sequence NN cord-001207-yjaiybwf 12 12 identities identity NNS cord-001207-yjaiybwf 12 13 to to IN cord-001207-yjaiybwf 12 14 known know VBN cord-001207-yjaiybwf 12 15 viruses virus NNS cord-001207-yjaiybwf 12 16 . . . cord-001207-yjaiybwf 13 1 The the DT cord-001207-yjaiybwf 13 2 percentage percentage NN cord-001207-yjaiybwf 13 3 of of IN cord-001207-yjaiybwf 13 4 detected detect VBN cord-001207-yjaiybwf 13 5 mammalian mammalian JJ cord-001207-yjaiybwf 13 6 virus virus NN cord-001207-yjaiybwf 13 7 sequences sequence NNS cord-001207-yjaiybwf 13 8 was be VBD cord-001207-yjaiybwf 13 9 highest high JJS cord-001207-yjaiybwf 13 10 ( ( -LRB- cord-001207-yjaiybwf 13 11 55–77 55–77 CD cord-001207-yjaiybwf 13 12 % % NN cord-001207-yjaiybwf 13 13 ) ) -RRB- cord-001207-yjaiybwf 13 14 in in IN cord-001207-yjaiybwf 13 15 the the DT cord-001207-yjaiybwf 13 16 samples sample NNS cord-001207-yjaiybwf 13 17 of of IN cord-001207-yjaiybwf 13 18 the the DT cord-001207-yjaiybwf 13 19 youngest young JJS cord-001207-yjaiybwf 13 20 piglets piglet NNS cord-001207-yjaiybwf 13 21 and and CC cord-001207-yjaiybwf 13 22 lowest low JJS cord-001207-yjaiybwf 13 23 ( ( -LRB- cord-001207-yjaiybwf 13 24 8–10 8–10 CD cord-001207-yjaiybwf 13 25 % % NN cord-001207-yjaiybwf 13 26 ) ) -RRB- cord-001207-yjaiybwf 13 27 in in IN cord-001207-yjaiybwf 13 28 the the DT cord-001207-yjaiybwf 13 29 samples sample NNS cord-001207-yjaiybwf 13 30 of of IN cord-001207-yjaiybwf 13 31 the the DT cord-001207-yjaiybwf 13 32 sows sow NNS cord-001207-yjaiybwf 13 33 . . . cord-001207-yjaiybwf 14 1 In in IN cord-001207-yjaiybwf 14 2 contrast contrast NN cord-001207-yjaiybwf 14 3 , , , cord-001207-yjaiybwf 14 4 the the DT cord-001207-yjaiybwf 14 5 percentage percentage NN cord-001207-yjaiybwf 14 6 of of IN cord-001207-yjaiybwf 14 7 bacteriophage bacteriophage NN cord-001207-yjaiybwf 14 8 sequences sequence NNS cord-001207-yjaiybwf 14 9 increased increase VBD cord-001207-yjaiybwf 14 10 from from IN cord-001207-yjaiybwf 14 11 22–44 22–44 CD cord-001207-yjaiybwf 14 12 % % NN cord-001207-yjaiybwf 14 13 in in IN cord-001207-yjaiybwf 14 14 the the DT cord-001207-yjaiybwf 14 15 youngest young JJS cord-001207-yjaiybwf 14 16 piglets piglet NNS cord-001207-yjaiybwf 14 17 to to IN cord-001207-yjaiybwf 14 18 approximately approximately RB cord-001207-yjaiybwf 14 19 90 90 CD cord-001207-yjaiybwf 14 20 % % NN cord-001207-yjaiybwf 14 21 in in IN cord-001207-yjaiybwf 14 22 the the DT cord-001207-yjaiybwf 14 23 sows sow NNS cord-001207-yjaiybwf 14 24 . . . cord-001207-yjaiybwf 15 1 The the DT cord-001207-yjaiybwf 15 2 dominating dominating JJ cord-001207-yjaiybwf 15 3 mammalian mammalian JJ cord-001207-yjaiybwf 15 4 viruses virus NNS cord-001207-yjaiybwf 15 5 differed differ VBD cord-001207-yjaiybwf 15 6 remarkably remarkably RB cord-001207-yjaiybwf 15 7 among among IN cord-001207-yjaiybwf 15 8 12 12 CD cord-001207-yjaiybwf 15 9 day day NN cord-001207-yjaiybwf 15 10 - - HYPH cord-001207-yjaiybwf 15 11 old old JJ cord-001207-yjaiybwf 15 12 piglets piglet NNS cord-001207-yjaiybwf 15 13 ( ( -LRB- cord-001207-yjaiybwf 15 14 kobuvirus kobuvirus NNP cord-001207-yjaiybwf 15 15 ) ) -RRB- cord-001207-yjaiybwf 15 16 , , , cord-001207-yjaiybwf 15 17 54 54 CD cord-001207-yjaiybwf 15 18 day day NN cord-001207-yjaiybwf 15 19 - - HYPH cord-001207-yjaiybwf 15 20 old old JJ cord-001207-yjaiybwf 15 21 piglets piglet NNS cord-001207-yjaiybwf 15 22 ( ( -LRB- cord-001207-yjaiybwf 15 23 boca- boca- NNP cord-001207-yjaiybwf 15 24 , , , cord-001207-yjaiybwf 15 25 dependo- dependo- NN cord-001207-yjaiybwf 15 26 and and CC cord-001207-yjaiybwf 15 27 pig pig NN cord-001207-yjaiybwf 15 28 stool stool NN cord-001207-yjaiybwf 15 29 - - HYPH cord-001207-yjaiybwf 15 30 associated associate VBN cord-001207-yjaiybwf 15 31 small small JJ cord-001207-yjaiybwf 15 32 circular circular JJ cord-001207-yjaiybwf 15 33 DNA dna NN cord-001207-yjaiybwf 15 34 virus virus NN cord-001207-yjaiybwf 15 35 [ [ -LRB- cord-001207-yjaiybwf 15 36 PigSCV PigSCV NNP cord-001207-yjaiybwf 15 37 ] ] -RRB- cord-001207-yjaiybwf 15 38 ) ) -RRB- cord-001207-yjaiybwf 15 39 and and CC cord-001207-yjaiybwf 15 40 the the DT cord-001207-yjaiybwf 15 41 sows sow NNS cord-001207-yjaiybwf 15 42 ( ( -LRB- cord-001207-yjaiybwf 15 43 PigSCV PigSCV NNP cord-001207-yjaiybwf 15 44 , , , cord-001207-yjaiybwf 15 45 circovirus circovirus NNP cord-001207-yjaiybwf 15 46 and and CC cord-001207-yjaiybwf 15 47 “ " `` cord-001207-yjaiybwf 15 48 circovirus circovirus NNP cord-001207-yjaiybwf 15 49 - - HYPH cord-001207-yjaiybwf 15 50 like like JJ cord-001207-yjaiybwf 15 51 ” " '' cord-001207-yjaiybwf 15 52 viruses virus NNS cord-001207-yjaiybwf 15 53 CB CB NNP cord-001207-yjaiybwf 16 1 -A -A : cord-001207-yjaiybwf 16 2 and and CC cord-001207-yjaiybwf 16 3 RW RW NNP cord-001207-yjaiybwf 16 4 - - HYPH cord-001207-yjaiybwf 16 5 A a NN cord-001207-yjaiybwf 16 6 ) ) -RRB- cord-001207-yjaiybwf 16 7 . . . cord-001207-yjaiybwf 17 1 In in IN cord-001207-yjaiybwf 17 2 addition addition NN cord-001207-yjaiybwf 17 3 , , , cord-001207-yjaiybwf 17 4 the the DT cord-001207-yjaiybwf 17 5 Shannon Shannon NNP cord-001207-yjaiybwf 17 6 index index NN cord-001207-yjaiybwf 17 7 , , , cord-001207-yjaiybwf 17 8 which which WDT cord-001207-yjaiybwf 17 9 reflects reflect VBZ cord-001207-yjaiybwf 17 10 the the DT cord-001207-yjaiybwf 17 11 diversity diversity NN cord-001207-yjaiybwf 17 12 of of IN cord-001207-yjaiybwf 17 13 sequences sequence NNS cord-001207-yjaiybwf 17 14 present present JJ cord-001207-yjaiybwf 17 15 in in IN cord-001207-yjaiybwf 17 16 a a DT cord-001207-yjaiybwf 17 17 sample sample NN cord-001207-yjaiybwf 17 18 , , , cord-001207-yjaiybwf 17 19 was be VBD cord-001207-yjaiybwf 17 20 generally generally RB cord-001207-yjaiybwf 17 21 higher high JJR cord-001207-yjaiybwf 17 22 for for IN cord-001207-yjaiybwf 17 23 the the DT cord-001207-yjaiybwf 17 24 sows sow NNS cord-001207-yjaiybwf 17 25 as as IN cord-001207-yjaiybwf 17 26 compared compare VBN cord-001207-yjaiybwf 17 27 to to IN cord-001207-yjaiybwf 17 28 the the DT cord-001207-yjaiybwf 17 29 piglets piglet NNS cord-001207-yjaiybwf 17 30 . . . cord-001207-yjaiybwf 18 1 No no DT cord-001207-yjaiybwf 18 2 consistent consistent JJ cord-001207-yjaiybwf 18 3 differences difference NNS cord-001207-yjaiybwf 18 4 in in IN cord-001207-yjaiybwf 18 5 the the DT cord-001207-yjaiybwf 18 6 virome virome JJ cord-001207-yjaiybwf 18 7 composition composition NN cord-001207-yjaiybwf 18 8 could could MD cord-001207-yjaiybwf 18 9 be be VB cord-001207-yjaiybwf 18 10 identified identify VBN cord-001207-yjaiybwf 18 11 between between IN cord-001207-yjaiybwf 18 12 the the DT cord-001207-yjaiybwf 18 13 viromes virome NNS cord-001207-yjaiybwf 18 14 of of IN cord-001207-yjaiybwf 18 15 the the DT cord-001207-yjaiybwf 18 16 probiotic probiotic JJ cord-001207-yjaiybwf 18 17 bacterium bacterium NN cord-001207-yjaiybwf 18 18 - - HYPH cord-001207-yjaiybwf 18 19 treated treat VBN cord-001207-yjaiybwf 18 20 group group NN cord-001207-yjaiybwf 18 21 and and CC cord-001207-yjaiybwf 18 22 the the DT cord-001207-yjaiybwf 18 23 control control NN cord-001207-yjaiybwf 18 24 group group NN cord-001207-yjaiybwf 18 25 . . . cord-001207-yjaiybwf 19 1 CONCLUSION conclusion NN cord-001207-yjaiybwf 19 2 : : : cord-001207-yjaiybwf 20 1 The the DT cord-001207-yjaiybwf 20 2 analysis analysis NN cord-001207-yjaiybwf 20 3 indicates indicate VBZ cord-001207-yjaiybwf 20 4 that that IN cord-001207-yjaiybwf 20 5 the the DT cord-001207-yjaiybwf 20 6 pig pig NN cord-001207-yjaiybwf 20 7 faecal faecal JJ cord-001207-yjaiybwf 20 8 virome virome NNP cord-001207-yjaiybwf 20 9 shows show VBZ cord-001207-yjaiybwf 20 10 a a DT cord-001207-yjaiybwf 20 11 high high JJ cord-001207-yjaiybwf 20 12 variability variability NN cord-001207-yjaiybwf 20 13 and and CC cord-001207-yjaiybwf 20 14 that that IN cord-001207-yjaiybwf 20 15 its -PRON- PRP$ cord-001207-yjaiybwf 20 16 general general JJ cord-001207-yjaiybwf 20 17 composition composition NN cord-001207-yjaiybwf 20 18 is be VBZ cord-001207-yjaiybwf 20 19 mainly mainly RB cord-001207-yjaiybwf 20 20 dependent dependent JJ cord-001207-yjaiybwf 20 21 on on IN cord-001207-yjaiybwf 20 22 the the DT cord-001207-yjaiybwf 20 23 age age NN cord-001207-yjaiybwf 20 24 of of IN cord-001207-yjaiybwf 20 25 the the DT cord-001207-yjaiybwf 20 26 pigs pig NNS cord-001207-yjaiybwf 20 27 . . . cord-001207-yjaiybwf 21 1 Changes change NNS cord-001207-yjaiybwf 21 2 caused cause VBN cord-001207-yjaiybwf 21 3 by by IN cord-001207-yjaiybwf 21 4 feeding feed VBG cord-001207-yjaiybwf 21 5 with with IN cord-001207-yjaiybwf 21 6 the the DT cord-001207-yjaiybwf 21 7 probiotic probiotic JJ cord-001207-yjaiybwf 21 8 bacterium bacterium NN cord-001207-yjaiybwf 21 9 E. E. NNP cord-001207-yjaiybwf 21 10 faecium faecium NN cord-001207-yjaiybwf 21 11 could could MD cord-001207-yjaiybwf 21 12 not not RB cord-001207-yjaiybwf 21 13 be be VB cord-001207-yjaiybwf 21 14 demonstrated demonstrate VBN cord-001207-yjaiybwf 21 15 using use VBG cord-001207-yjaiybwf 21 16 the the DT cord-001207-yjaiybwf 21 17 applied apply VBN cord-001207-yjaiybwf 21 18 metagenomics metagenomics NN cord-001207-yjaiybwf 21 19 method method NN cord-001207-yjaiybwf 21 20 . . . cord-001207-yjaiybwf 22 1 The the DT cord-001207-yjaiybwf 22 2 viral viral JJ cord-001207-yjaiybwf 22 3 community community NN cord-001207-yjaiybwf 22 4 present present JJ cord-001207-yjaiybwf 22 5 in in IN cord-001207-yjaiybwf 22 6 faeces faece NNS cord-001207-yjaiybwf 22 7 is be VBZ cord-001207-yjaiybwf 22 8 composed compose VBN cord-001207-yjaiybwf 22 9 of of IN cord-001207-yjaiybwf 22 10 a a DT cord-001207-yjaiybwf 22 11 variety variety NN cord-001207-yjaiybwf 22 12 of of IN cord-001207-yjaiybwf 22 13 viruses virus NNS cord-001207-yjaiybwf 22 14 originating originate VBG cord-001207-yjaiybwf 22 15 from from IN cord-001207-yjaiybwf 22 16 the the DT cord-001207-yjaiybwf 22 17 gut gut NN cord-001207-yjaiybwf 22 18 tissue tissue NN cord-001207-yjaiybwf 22 19 , , , cord-001207-yjaiybwf 22 20 from from IN cord-001207-yjaiybwf 22 21 intestinal intestinal JJ cord-001207-yjaiybwf 22 22 microorganisms microorganism NNS cord-001207-yjaiybwf 22 23 or or CC cord-001207-yjaiybwf 22 24 from from IN cord-001207-yjaiybwf 22 25 ingested ingest VBN cord-001207-yjaiybwf 22 26 food food NN cord-001207-yjaiybwf 22 27 . . . cord-001207-yjaiybwf 23 1 The the DT cord-001207-yjaiybwf 23 2 totality totality NN cord-001207-yjaiybwf 23 3 of of IN cord-001207-yjaiybwf 23 4 viruses virus NNS cord-001207-yjaiybwf 23 5 present present JJ cord-001207-yjaiybwf 23 6 in in IN cord-001207-yjaiybwf 23 7 faeces faece NNS cord-001207-yjaiybwf 23 8 has have VBZ cord-001207-yjaiybwf 23 9 also also RB cord-001207-yjaiybwf 23 10 been be VBN cord-001207-yjaiybwf 23 11 frequently frequently RB cord-001207-yjaiybwf 23 12 designated designate VBN cord-001207-yjaiybwf 23 13 as as IN cord-001207-yjaiybwf 23 14 the the DT cord-001207-yjaiybwf 23 15 faecal faecal JJ cord-001207-yjaiybwf 23 16 virome virome NN cord-001207-yjaiybwf 23 17 [ [ -LRB- cord-001207-yjaiybwf 23 18 1 1 CD cord-001207-yjaiybwf 23 19 , , , cord-001207-yjaiybwf 23 20 2 2 CD cord-001207-yjaiybwf 23 21 ] ] -RRB- cord-001207-yjaiybwf 23 22 . . . cord-001207-yjaiybwf 24 1 The the DT cord-001207-yjaiybwf 24 2 functions function NNS cord-001207-yjaiybwf 24 3 of of IN cord-001207-yjaiybwf 24 4 the the DT cord-001207-yjaiybwf 24 5 faecal faecal JJ cord-001207-yjaiybwf 24 6 virome virome NNP cord-001207-yjaiybwf 24 7 are be VBP cord-001207-yjaiybwf 24 8 supposed suppose VBN cord-001207-yjaiybwf 24 9 to to TO cord-001207-yjaiybwf 24 10 be be VB cord-001207-yjaiybwf 24 11 manifold manifold JJ cord-001207-yjaiybwf 24 12 , , , cord-001207-yjaiybwf 24 13 which which WDT cord-001207-yjaiybwf 24 14 include include VBP cord-001207-yjaiybwf 24 15 roles role NNS cord-001207-yjaiybwf 24 16 for for IN cord-001207-yjaiybwf 24 17 the the DT cord-001207-yjaiybwf 24 18 viruses virus NNS cord-001207-yjaiybwf 24 19 as as IN cord-001207-yjaiybwf 24 20 pathogens pathogen NNS cord-001207-yjaiybwf 24 21 , , , cord-001207-yjaiybwf 24 22 regulators regulator NNS cord-001207-yjaiybwf 24 23 of of IN cord-001207-yjaiybwf 24 24 bacterial bacterial JJ cord-001207-yjaiybwf 24 25 growth growth NN cord-001207-yjaiybwf 24 26 , , , cord-001207-yjaiybwf 24 27 gene gene NN cord-001207-yjaiybwf 24 28 - - HYPH cord-001207-yjaiybwf 24 29 transfer transfer NN cord-001207-yjaiybwf 24 30 vehicles vehicle NNS cord-001207-yjaiybwf 24 31 and and CC cord-001207-yjaiybwf 24 32 modulators modulator NNS cord-001207-yjaiybwf 24 33 of of IN cord-001207-yjaiybwf 24 34 the the DT cord-001207-yjaiybwf 24 35 immune immune JJ cord-001207-yjaiybwf 24 36 system system NN cord-001207-yjaiybwf 24 37 [ [ -LRB- cord-001207-yjaiybwf 24 38 3 3 CD cord-001207-yjaiybwf 24 39 ] ] -RRB- cord-001207-yjaiybwf 24 40 [ [ -LRB- cord-001207-yjaiybwf 24 41 4 4 CD cord-001207-yjaiybwf 24 42 ] ] -RRB- cord-001207-yjaiybwf 24 43 [ [ -LRB- cord-001207-yjaiybwf 24 44 5 5 CD cord-001207-yjaiybwf 24 45 ] ] -RRB- cord-001207-yjaiybwf 24 46 [ [ -LRB- cord-001207-yjaiybwf 24 47 6 6 CD cord-001207-yjaiybwf 24 48 ] ] -RRB- cord-001207-yjaiybwf 24 49 . . . cord-001207-yjaiybwf 25 1 Early early JJ cord-001207-yjaiybwf 25 2 insights insight NNS cord-001207-yjaiybwf 25 3 into into IN cord-001207-yjaiybwf 25 4 the the DT cord-001207-yjaiybwf 25 5 composition composition NN cord-001207-yjaiybwf 25 6 of of IN cord-001207-yjaiybwf 25 7 the the DT cord-001207-yjaiybwf 25 8 human human JJ cord-001207-yjaiybwf 25 9 faecal faecal JJ cord-001207-yjaiybwf 25 10 virome virome NNP cord-001207-yjaiybwf 25 11 were be VBD cord-001207-yjaiybwf 25 12 provided provide VBN cord-001207-yjaiybwf 25 13 by by IN cord-001207-yjaiybwf 25 14 random random JJ cord-001207-yjaiybwf 25 15 cloning cloning NN cord-001207-yjaiybwf 25 16 strategies strategy NNS cord-001207-yjaiybwf 25 17 [ [ -LRB- cord-001207-yjaiybwf 25 18 7 7 CD cord-001207-yjaiybwf 25 19 , , , cord-001207-yjaiybwf 25 20 8 8 CD cord-001207-yjaiybwf 25 21 ] ] -RRB- cord-001207-yjaiybwf 25 22 . . . cord-001207-yjaiybwf 26 1 Later later RB cord-001207-yjaiybwf 26 2 on on RB cord-001207-yjaiybwf 26 3 , , , cord-001207-yjaiybwf 26 4 the the DT cord-001207-yjaiybwf 26 5 availability availability NN cord-001207-yjaiybwf 26 6 of of IN cord-001207-yjaiybwf 26 7 deep deep JJ cord-001207-yjaiybwf 26 8 sequencing sequencing NN cord-001207-yjaiybwf 26 9 methods method NNS cord-001207-yjaiybwf 26 10 lead lead VBP cord-001207-yjaiybwf 26 11 to to IN cord-001207-yjaiybwf 26 12 more more JJR cord-001207-yjaiybwf 26 13 comprehensive comprehensive JJ cord-001207-yjaiybwf 26 14 analyses analysis NNS cord-001207-yjaiybwf 26 15 of of IN cord-001207-yjaiybwf 26 16 faecal faecal JJ cord-001207-yjaiybwf 26 17 viromes virome NNS cord-001207-yjaiybwf 26 18 [ [ -LRB- cord-001207-yjaiybwf 26 19 1 1 CD cord-001207-yjaiybwf 26 20 , , , cord-001207-yjaiybwf 26 21 9 9 CD cord-001207-yjaiybwf 26 22 ] ] -RRB- cord-001207-yjaiybwf 26 23 , , , cord-001207-yjaiybwf 26 24 including include VBG cord-001207-yjaiybwf 26 25 the the DT cord-001207-yjaiybwf 26 26 development development NN cord-001207-yjaiybwf 26 27 of of IN cord-001207-yjaiybwf 26 28 processcontrolled processcontrolled JJ cord-001207-yjaiybwf 26 29 techniques technique NNS cord-001207-yjaiybwf 26 30 enabling enable VBG cord-001207-yjaiybwf 26 31 comparison comparison NN cord-001207-yjaiybwf 26 32 of of IN cord-001207-yjaiybwf 26 33 different different JJ cord-001207-yjaiybwf 26 34 analyses analysis NNS cord-001207-yjaiybwf 26 35 [ [ -LRB- cord-001207-yjaiybwf 26 36 10 10 CD cord-001207-yjaiybwf 26 37 ] ] -RRB- cord-001207-yjaiybwf 26 38 . . . cord-001207-yjaiybwf 27 1 The the DT cord-001207-yjaiybwf 27 2 composition composition NN cord-001207-yjaiybwf 27 3 of of IN cord-001207-yjaiybwf 27 4 the the DT cord-001207-yjaiybwf 27 5 faecal faecal JJ cord-001207-yjaiybwf 27 6 virome virome NN cord-001207-yjaiybwf 27 7 of of IN cord-001207-yjaiybwf 27 8 pigs pig NNS cord-001207-yjaiybwf 27 9 has have VBZ cord-001207-yjaiybwf 27 10 been be VBN cord-001207-yjaiybwf 27 11 studied study VBN cord-001207-yjaiybwf 27 12 recently recently RB cord-001207-yjaiybwf 27 13 [ [ -LRB- cord-001207-yjaiybwf 27 14 2 2 CD cord-001207-yjaiybwf 27 15 , , , cord-001207-yjaiybwf 27 16 10 10 CD cord-001207-yjaiybwf 27 17 , , , cord-001207-yjaiybwf 27 18 11 11 CD cord-001207-yjaiybwf 27 19 ] ] -RRB- cord-001207-yjaiybwf 27 20 . . . cord-001207-yjaiybwf 28 1 Although although IN cord-001207-yjaiybwf 28 2 samples sample NNS cord-001207-yjaiybwf 28 3 derived derive VBN cord-001207-yjaiybwf 28 4 from from IN cord-001207-yjaiybwf 28 5 different different JJ cord-001207-yjaiybwf 28 6 continents continent NNS cord-001207-yjaiybwf 28 7 had have VBD cord-001207-yjaiybwf 28 8 been be VBN cord-001207-yjaiybwf 28 9 analysed analyse VBN cord-001207-yjaiybwf 28 10 in in IN cord-001207-yjaiybwf 28 11 these these DT cord-001207-yjaiybwf 28 12 studies study NNS cord-001207-yjaiybwf 28 13 , , , cord-001207-yjaiybwf 28 14 the the DT cord-001207-yjaiybwf 28 15 general general JJ cord-001207-yjaiybwf 28 16 composition composition NN cord-001207-yjaiybwf 28 17 was be VBD cord-001207-yjaiybwf 28 18 found find VBN cord-001207-yjaiybwf 28 19 to to TO cord-001207-yjaiybwf 28 20 be be VB cord-001207-yjaiybwf 28 21 similar similar JJ cord-001207-yjaiybwf 28 22 . . . cord-001207-yjaiybwf 29 1 The the DT cord-001207-yjaiybwf 29 2 majority majority NN cord-001207-yjaiybwf 29 3 of of IN cord-001207-yjaiybwf 29 4 the the DT cord-001207-yjaiybwf 29 5 detected detect VBN cord-001207-yjaiybwf 29 6 virus virus NN cord-001207-yjaiybwf 29 7 sequences sequence NNS cord-001207-yjaiybwf 29 8 belonged belong VBD cord-001207-yjaiybwf 29 9 to to IN cord-001207-yjaiybwf 29 10 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 29 11 and and CC cord-001207-yjaiybwf 29 12 pig pig NN cord-001207-yjaiybwf 29 13 viruses virus NNS cord-001207-yjaiybwf 29 14 . . . cord-001207-yjaiybwf 30 1 Only only RB cord-001207-yjaiybwf 30 2 a a DT cord-001207-yjaiybwf 30 3 few few JJ cord-001207-yjaiybwf 30 4 sequences sequence NNS cord-001207-yjaiybwf 30 5 belonged belong VBD cord-001207-yjaiybwf 30 6 to to TO cord-001207-yjaiybwf 30 7 plant plant NN cord-001207-yjaiybwf 30 8 viruses virus NNS cord-001207-yjaiybwf 30 9 as as RB cord-001207-yjaiybwf 30 10 well well RB cord-001207-yjaiybwf 30 11 as as IN cord-001207-yjaiybwf 30 12 other other JJ cord-001207-yjaiybwf 30 13 viruses virus NNS cord-001207-yjaiybwf 30 14 . . . cord-001207-yjaiybwf 31 1 Most Most JJS cord-001207-yjaiybwf 31 2 of of IN cord-001207-yjaiybwf 31 3 the the DT cord-001207-yjaiybwf 31 4 bacteriophage bacteriophage NN cord-001207-yjaiybwf 31 5 sequences sequence NNS cord-001207-yjaiybwf 31 6 originated originate VBD cord-001207-yjaiybwf 31 7 from from IN cord-001207-yjaiybwf 31 8 viruses virus NNS cord-001207-yjaiybwf 31 9 belonging belong VBG cord-001207-yjaiybwf 31 10 to to IN cord-001207-yjaiybwf 31 11 the the DT cord-001207-yjaiybwf 31 12 families family NNS cord-001207-yjaiybwf 31 13 Siphoviridae Siphoviridae NNP cord-001207-yjaiybwf 31 14 , , , cord-001207-yjaiybwf 31 15 Microviridae Microviridae NNP cord-001207-yjaiybwf 31 16 and and CC cord-001207-yjaiybwf 31 17 Myoviridae Myoviridae NNP cord-001207-yjaiybwf 31 18 [ [ -LRB- cord-001207-yjaiybwf 31 19 10 10 CD cord-001207-yjaiybwf 31 20 ] ] -RRB- cord-001207-yjaiybwf 31 21 . . . cord-001207-yjaiybwf 32 1 The the DT cord-001207-yjaiybwf 32 2 most most RBS cord-001207-yjaiybwf 32 3 abundant abundant JJ cord-001207-yjaiybwf 32 4 porcine porcine JJ cord-001207-yjaiybwf 32 5 viruses virus NNS cord-001207-yjaiybwf 32 6 were be VBD cord-001207-yjaiybwf 32 7 kobuvirus kobuvirus NNP cord-001207-yjaiybwf 32 8 , , , cord-001207-yjaiybwf 32 9 rotavirus rotavirus NN cord-001207-yjaiybwf 32 10 , , , cord-001207-yjaiybwf 32 11 pig pig NN cord-001207-yjaiybwf 32 12 stool stool NN cord-001207-yjaiybwf 32 13 - - HYPH cord-001207-yjaiybwf 32 14 associated associate VBN cord-001207-yjaiybwf 32 15 small small JJ cord-001207-yjaiybwf 32 16 circular circular JJ cord-001207-yjaiybwf 32 17 DNA dna NN cord-001207-yjaiybwf 32 18 virus virus NN cord-001207-yjaiybwf 32 19 ( ( -LRB- cord-001207-yjaiybwf 32 20 PigSCV PigSCV NNP cord-001207-yjaiybwf 32 21 ) ) -RRB- cord-001207-yjaiybwf 32 22 , , , cord-001207-yjaiybwf 32 23 astrovirus astrovirus NNP cord-001207-yjaiybwf 32 24 , , , cord-001207-yjaiybwf 32 25 sapovirus sapovirus NNP cord-001207-yjaiybwf 32 26 and and CC cord-001207-yjaiybwf 32 27 enterovirus enterovirus NN cord-001207-yjaiybwf 32 28 B. B. NNP cord-001207-yjaiybwf 32 29 Most Most JJS cord-001207-yjaiybwf 32 30 of of IN cord-001207-yjaiybwf 32 31 them -PRON- PRP cord-001207-yjaiybwf 32 32 represent represent VBP cord-001207-yjaiybwf 32 33 widely widely RB cord-001207-yjaiybwf 32 34 distributed distribute VBN cord-001207-yjaiybwf 32 35 enteric enteric JJ cord-001207-yjaiybwf 32 36 viruses virus NNS cord-001207-yjaiybwf 32 37 of of IN cord-001207-yjaiybwf 32 38 pigs pig NNS cord-001207-yjaiybwf 32 39 [ [ -LRB- cord-001207-yjaiybwf 32 40 2 2 CD cord-001207-yjaiybwf 32 41 , , , cord-001207-yjaiybwf 32 42 10 10 CD cord-001207-yjaiybwf 32 43 , , , cord-001207-yjaiybwf 32 44 11 11 CD cord-001207-yjaiybwf 32 45 ] ] -RRB- cord-001207-yjaiybwf 32 46 . . . cord-001207-yjaiybwf 33 1 Whereas whereas IN cord-001207-yjaiybwf 33 2 rotaviruses rotavirus NNS cord-001207-yjaiybwf 33 3 are be VBP cord-001207-yjaiybwf 33 4 well well RB cord-001207-yjaiybwf 33 5 - - HYPH cord-001207-yjaiybwf 33 6 known know VBN cord-001207-yjaiybwf 33 7 pathogens pathogen NNS cord-001207-yjaiybwf 33 8 of of IN cord-001207-yjaiybwf 33 9 piglets piglet NNS cord-001207-yjaiybwf 33 10 , , , cord-001207-yjaiybwf 33 11 which which WDT cord-001207-yjaiybwf 33 12 may may MD cord-001207-yjaiybwf 33 13 lead lead VB cord-001207-yjaiybwf 33 14 to to IN cord-001207-yjaiybwf 33 15 diarrhoea diarrhoea NN cord-001207-yjaiybwf 33 16 [ [ -LRB- cord-001207-yjaiybwf 33 17 12 12 CD cord-001207-yjaiybwf 33 18 , , , cord-001207-yjaiybwf 33 19 13 13 CD cord-001207-yjaiybwf 33 20 , , , cord-001207-yjaiybwf 33 21 14 14 CD cord-001207-yjaiybwf 33 22 ] ] -RRB- cord-001207-yjaiybwf 33 23 , , , cord-001207-yjaiybwf 33 24 the the DT cord-001207-yjaiybwf 33 25 clinical clinical JJ cord-001207-yjaiybwf 33 26 importance importance NN cord-001207-yjaiybwf 33 27 of of IN cord-001207-yjaiybwf 33 28 the the DT cord-001207-yjaiybwf 33 29 other other JJ cord-001207-yjaiybwf 33 30 viruses virus NNS cord-001207-yjaiybwf 33 31 is be VBZ cord-001207-yjaiybwf 33 32 a a DT cord-001207-yjaiybwf 33 33 subject subject NN cord-001207-yjaiybwf 33 34 of of IN cord-001207-yjaiybwf 33 35 controversy controversy NN cord-001207-yjaiybwf 33 36 [ [ -LRB- cord-001207-yjaiybwf 33 37 10 10 CD cord-001207-yjaiybwf 33 38 , , , cord-001207-yjaiybwf 33 39 [ [ -LRB- cord-001207-yjaiybwf 33 40 15 15 CD cord-001207-yjaiybwf 33 41 ] ] -RRB- cord-001207-yjaiybwf 33 42 [ [ -LRB- cord-001207-yjaiybwf 33 43 16 16 CD cord-001207-yjaiybwf 33 44 ] ] -RRB- cord-001207-yjaiybwf 33 45 [ [ -LRB- cord-001207-yjaiybwf 33 46 17 17 CD cord-001207-yjaiybwf 33 47 ] ] -RRB- cord-001207-yjaiybwf 33 48 [ [ -LRB- cord-001207-yjaiybwf 33 49 18 18 CD cord-001207-yjaiybwf 33 50 ] ] -RRB- cord-001207-yjaiybwf 33 51 [ [ -LRB- cord-001207-yjaiybwf 33 52 19 19 CD cord-001207-yjaiybwf 33 53 ] ] -RRB- cord-001207-yjaiybwf 33 54 [ [ -LRB- cord-001207-yjaiybwf 33 55 20 20 CD cord-001207-yjaiybwf 33 56 ] ] -RRB- cord-001207-yjaiybwf 33 57 [ [ -LRB- cord-001207-yjaiybwf 33 58 21 21 CD cord-001207-yjaiybwf 33 59 ] ] -RRB- cord-001207-yjaiybwf 33 60 [ [ -LRB- cord-001207-yjaiybwf 33 61 22 22 CD cord-001207-yjaiybwf 33 62 ] ] -RRB- cord-001207-yjaiybwf 33 63 . . . cord-001207-yjaiybwf 34 1 Only only RB cord-001207-yjaiybwf 34 2 little little JJ cord-001207-yjaiybwf 34 3 is be VBZ cord-001207-yjaiybwf 34 4 known know VBN cord-001207-yjaiybwf 34 5 about about IN cord-001207-yjaiybwf 34 6 the the DT cord-001207-yjaiybwf 34 7 stability stability NN cord-001207-yjaiybwf 34 8 and and CC cord-001207-yjaiybwf 34 9 dynamics dynamic NNS cord-001207-yjaiybwf 34 10 of of IN cord-001207-yjaiybwf 34 11 the the DT cord-001207-yjaiybwf 34 12 faecal faecal JJ cord-001207-yjaiybwf 34 13 virome virome NN cord-001207-yjaiybwf 34 14 under under IN cord-001207-yjaiybwf 34 15 different different JJ cord-001207-yjaiybwf 34 16 conditions condition NNS cord-001207-yjaiybwf 34 17 . . . cord-001207-yjaiybwf 35 1 For for IN cord-001207-yjaiybwf 35 2 the the DT cord-001207-yjaiybwf 35 3 human human JJ cord-001207-yjaiybwf 35 4 faecal faecal JJ cord-001207-yjaiybwf 35 5 virome virome NN cord-001207-yjaiybwf 35 6 , , , cord-001207-yjaiybwf 35 7 Reyes Reyes NNP cord-001207-yjaiybwf 35 8 et et NNP cord-001207-yjaiybwf 35 9 al al NNP cord-001207-yjaiybwf 35 10 . . . cord-001207-yjaiybwf 36 1 [ [ -LRB- cord-001207-yjaiybwf 36 2 9 9 CD cord-001207-yjaiybwf 36 3 ] ] -RRB- cord-001207-yjaiybwf 36 4 investigated investigate VBD cord-001207-yjaiybwf 36 5 the the DT cord-001207-yjaiybwf 36 6 intra intra JJ cord-001207-yjaiybwf 36 7 - - JJ cord-001207-yjaiybwf 36 8 and and CC cord-001207-yjaiybwf 36 9 interpersonal interpersonal JJ cord-001207-yjaiybwf 36 10 variation variation NN cord-001207-yjaiybwf 36 11 by by IN cord-001207-yjaiybwf 36 12 analysing analyse VBG cord-001207-yjaiybwf 36 13 faeces faece NNS cord-001207-yjaiybwf 36 14 of of IN cord-001207-yjaiybwf 36 15 monozygotic monozygotic JJ cord-001207-yjaiybwf 36 16 twins twin NNS cord-001207-yjaiybwf 36 17 and and CC cord-001207-yjaiybwf 36 18 their -PRON- PRP$ cord-001207-yjaiybwf 36 19 mothers mother NNS cord-001207-yjaiybwf 36 20 at at IN cord-001207-yjaiybwf 36 21 different different JJ cord-001207-yjaiybwf 36 22 time time NN cord-001207-yjaiybwf 36 23 - - HYPH cord-001207-yjaiybwf 36 24 points point NNS cord-001207-yjaiybwf 36 25 . . . cord-001207-yjaiybwf 37 1 By by IN cord-001207-yjaiybwf 37 2 this this DT cord-001207-yjaiybwf 37 3 , , , cord-001207-yjaiybwf 37 4 it -PRON- PRP cord-001207-yjaiybwf 37 5 was be VBD cord-001207-yjaiybwf 37 6 found find VBN cord-001207-yjaiybwf 37 7 that that IN cord-001207-yjaiybwf 37 8 the the DT cord-001207-yjaiybwf 37 9 viromes virome NNS cord-001207-yjaiybwf 37 10 were be VBD cord-001207-yjaiybwf 37 11 unique unique JJ cord-001207-yjaiybwf 37 12 to to IN cord-001207-yjaiybwf 37 13 the the DT cord-001207-yjaiybwf 37 14 individuals individual NNS cord-001207-yjaiybwf 37 15 regardless regardless RB cord-001207-yjaiybwf 37 16 of of IN cord-001207-yjaiybwf 37 17 their -PRON- PRP$ cord-001207-yjaiybwf 37 18 degree degree NN cord-001207-yjaiybwf 37 19 of of IN cord-001207-yjaiybwf 37 20 genetic genetic JJ cord-001207-yjaiybwf 37 21 relatedness relatedness NN cord-001207-yjaiybwf 37 22 . . . cord-001207-yjaiybwf 38 1 Minot Minot NNP cord-001207-yjaiybwf 38 2 et et NNP cord-001207-yjaiybwf 38 3 al al NNP cord-001207-yjaiybwf 38 4 . . . cord-001207-yjaiybwf 39 1 [ [ -LRB- cord-001207-yjaiybwf 39 2 1 1 CD cord-001207-yjaiybwf 39 3 ] ] -RRB- cord-001207-yjaiybwf 39 4 analysed analyse VBD cord-001207-yjaiybwf 39 5 the the DT cord-001207-yjaiybwf 39 6 inter inter JJ cord-001207-yjaiybwf 39 7 - - JJ cord-001207-yjaiybwf 39 8 individual individual JJ cord-001207-yjaiybwf 39 9 variation variation NN cord-001207-yjaiybwf 39 10 of of IN cord-001207-yjaiybwf 39 11 the the DT cord-001207-yjaiybwf 39 12 human human JJ cord-001207-yjaiybwf 39 13 faecal faecal JJ cord-001207-yjaiybwf 39 14 virome virome NN cord-001207-yjaiybwf 39 15 and and CC cord-001207-yjaiybwf 39 16 its -PRON- PRP$ cord-001207-yjaiybwf 39 17 dynamic dynamic JJ cord-001207-yjaiybwf 39 18 response response NN cord-001207-yjaiybwf 39 19 to to IN cord-001207-yjaiybwf 39 20 diet diet NN cord-001207-yjaiybwf 39 21 . . . cord-001207-yjaiybwf 40 1 It -PRON- PRP cord-001207-yjaiybwf 40 2 was be VBD cord-001207-yjaiybwf 40 3 shown show VBN cord-001207-yjaiybwf 40 4 that that IN cord-001207-yjaiybwf 40 5 the the DT cord-001207-yjaiybwf 40 6 largest large JJS cord-001207-yjaiybwf 40 7 source source NN cord-001207-yjaiybwf 40 8 of of IN cord-001207-yjaiybwf 40 9 variance variance NN cord-001207-yjaiybwf 40 10 among among IN cord-001207-yjaiybwf 40 11 the the DT cord-001207-yjaiybwf 40 12 viromes virome NNS cord-001207-yjaiybwf 40 13 was be VBD cord-001207-yjaiybwf 40 14 caused cause VBN cord-001207-yjaiybwf 40 15 by by IN cord-001207-yjaiybwf 40 16 interpersonal interpersonal JJ cord-001207-yjaiybwf 40 17 variations variation NNS cord-001207-yjaiybwf 40 18 and and CC cord-001207-yjaiybwf 40 19 not not RB cord-001207-yjaiybwf 40 20 by by IN cord-001207-yjaiybwf 40 21 the the DT cord-001207-yjaiybwf 40 22 diet diet NN cord-001207-yjaiybwf 40 23 . . . cord-001207-yjaiybwf 41 1 A a DT cord-001207-yjaiybwf 41 2 high high JJ cord-001207-yjaiybwf 41 3 interpersonal interpersonal JJ cord-001207-yjaiybwf 41 4 diversity diversity NN cord-001207-yjaiybwf 41 5 of of IN cord-001207-yjaiybwf 41 6 gut gut NN cord-001207-yjaiybwf 41 7 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 41 8 was be VBD cord-001207-yjaiybwf 41 9 also also RB cord-001207-yjaiybwf 41 10 described describe VBN cord-001207-yjaiybwf 41 11 in in IN cord-001207-yjaiybwf 41 12 two two CD cord-001207-yjaiybwf 41 13 humans human NNS cord-001207-yjaiybwf 41 14 which which WDT cord-001207-yjaiybwf 41 15 were be VBD cord-001207-yjaiybwf 41 16 monitored monitor VBN cord-001207-yjaiybwf 41 17 over over IN cord-001207-yjaiybwf 41 18 a a DT cord-001207-yjaiybwf 41 19 2.5 2.5 CD cord-001207-yjaiybwf 41 20 year year NN cord-001207-yjaiybwf 41 21 period period NN cord-001207-yjaiybwf 41 22 [ [ -LRB- cord-001207-yjaiybwf 41 23 23 23 CD cord-001207-yjaiybwf 41 24 ] ] -RRB- cord-001207-yjaiybwf 41 25 . . . cord-001207-yjaiybwf 42 1 In in IN cord-001207-yjaiybwf 42 2 another another DT cord-001207-yjaiybwf 42 3 study study NN cord-001207-yjaiybwf 42 4 , , , cord-001207-yjaiybwf 42 5 a a DT cord-001207-yjaiybwf 42 6 much much RB cord-001207-yjaiybwf 42 7 lower low JJR cord-001207-yjaiybwf 42 8 diversity diversity NN cord-001207-yjaiybwf 42 9 of of IN cord-001207-yjaiybwf 42 10 the the DT cord-001207-yjaiybwf 42 11 virus virus NN cord-001207-yjaiybwf 42 12 community community NN cord-001207-yjaiybwf 42 13 was be VBD cord-001207-yjaiybwf 42 14 found find VBN cord-001207-yjaiybwf 42 15 in in IN cord-001207-yjaiybwf 42 16 infants infant NNS cord-001207-yjaiybwf 42 17 as as IN cord-001207-yjaiybwf 42 18 compared compare VBN cord-001207-yjaiybwf 42 19 to to IN cord-001207-yjaiybwf 42 20 adults adult NNS cord-001207-yjaiybwf 42 21 [ [ -LRB- cord-001207-yjaiybwf 42 22 24 24 CD cord-001207-yjaiybwf 42 23 ] ] -RRB- cord-001207-yjaiybwf 42 24 . . . cord-001207-yjaiybwf 43 1 Although although IN cord-001207-yjaiybwf 43 2 this this DT cord-001207-yjaiybwf 43 3 study study NN cord-001207-yjaiybwf 43 4 has have VBZ cord-001207-yjaiybwf 43 5 been be VBN cord-001207-yjaiybwf 43 6 conducted conduct VBN cord-001207-yjaiybwf 43 7 by by IN cord-001207-yjaiybwf 43 8 cloning clone VBG cord-001207-yjaiybwf 43 9 followed follow VBN cord-001207-yjaiybwf 43 10 by by IN cord-001207-yjaiybwf 43 11 classical classical JJ cord-001207-yjaiybwf 43 12 sequencing sequencing NN cord-001207-yjaiybwf 43 13 , , , cord-001207-yjaiybwf 43 14 mathematical mathematical JJ cord-001207-yjaiybwf 43 15 modelling modelling NN cord-001207-yjaiybwf 43 16 of of IN cord-001207-yjaiybwf 43 17 the the DT cord-001207-yjaiybwf 43 18 derived derive VBN cord-001207-yjaiybwf 43 19 sequence sequence NN cord-001207-yjaiybwf 43 20 data datum NNS cord-001207-yjaiybwf 43 21 indicated indicate VBD cord-001207-yjaiybwf 43 22 that that IN cord-001207-yjaiybwf 43 23 the the DT cord-001207-yjaiybwf 43 24 virome virome NN cord-001207-yjaiybwf 43 25 of of IN cord-001207-yjaiybwf 43 26 adults adult NNS cord-001207-yjaiybwf 43 27 was be VBD cord-001207-yjaiybwf 43 28 composed compose VBN cord-001207-yjaiybwf 43 29 of of IN cord-001207-yjaiybwf 43 30 approximately approximately RB cord-001207-yjaiybwf 43 31 2000 2000 CD cord-001207-yjaiybwf 43 32 genotypes genotype NNS cord-001207-yjaiybwf 43 33 as as IN cord-001207-yjaiybwf 43 34 compared compare VBN cord-001207-yjaiybwf 43 35 to to IN cord-001207-yjaiybwf 43 36 only only RB cord-001207-yjaiybwf 43 37 8 8 CD cord-001207-yjaiybwf 43 38 genotypes genotype NNS cord-001207-yjaiybwf 43 39 in in IN cord-001207-yjaiybwf 43 40 one one CD cord-001207-yjaiybwf 43 41 week week NN cord-001207-yjaiybwf 43 42 - - HYPH cord-001207-yjaiybwf 43 43 old old JJ cord-001207-yjaiybwf 43 44 infants infant NNS cord-001207-yjaiybwf 43 45 . . . cord-001207-yjaiybwf 44 1 The the DT cord-001207-yjaiybwf 44 2 observed observed JJ cord-001207-yjaiybwf 44 3 beneficial beneficial JJ cord-001207-yjaiybwf 44 4 effects effect NNS cord-001207-yjaiybwf 44 5 of of IN cord-001207-yjaiybwf 44 6 probiotic probiotic JJ cord-001207-yjaiybwf 44 7 bacteria bacteria NNS cord-001207-yjaiybwf 44 8 on on IN cord-001207-yjaiybwf 44 9 enteric enteric JJ cord-001207-yjaiybwf 44 10 virus virus NN cord-001207-yjaiybwf 44 11 infections infection NNS cord-001207-yjaiybwf 44 12 have have VBP cord-001207-yjaiybwf 44 13 been be VBN cord-001207-yjaiybwf 44 14 recently recently RB cord-001207-yjaiybwf 44 15 reviewed review VBN cord-001207-yjaiybwf 44 16 by by IN cord-001207-yjaiybwf 44 17 Colbere Colbere NNP cord-001207-yjaiybwf 44 18 - - HYPH cord-001207-yjaiybwf 44 19 Garapin Garapin NNP cord-001207-yjaiybwf 44 20 et et FW cord-001207-yjaiybwf 44 21 al al NNP cord-001207-yjaiybwf 44 22 . . . cord-001207-yjaiybwf 45 1 [ [ -LRB- cord-001207-yjaiybwf 45 2 6 6 CD cord-001207-yjaiybwf 45 3 ] ] -RRB- cord-001207-yjaiybwf 45 4 . . . cord-001207-yjaiybwf 46 1 This this DT cord-001207-yjaiybwf 46 2 includes include VBZ cord-001207-yjaiybwf 46 3 clinical clinical JJ cord-001207-yjaiybwf 46 4 studies study NNS cord-001207-yjaiybwf 46 5 showing show VBG cord-001207-yjaiybwf 46 6 beneficial beneficial JJ cord-001207-yjaiybwf 46 7 effects effect NNS cord-001207-yjaiybwf 46 8 of of IN cord-001207-yjaiybwf 46 9 probiotic probiotic JJ cord-001207-yjaiybwf 46 10 bacteria bacteria NNS cord-001207-yjaiybwf 46 11 in in IN cord-001207-yjaiybwf 46 12 children child NNS cord-001207-yjaiybwf 46 13 with with IN cord-001207-yjaiybwf 46 14 rotavirus rotavirus NN cord-001207-yjaiybwf 46 15 - - HYPH cord-001207-yjaiybwf 46 16 caused cause VBN cord-001207-yjaiybwf 46 17 diarrhoea diarrhoea NN cord-001207-yjaiybwf 46 18 [ [ -LRB- cord-001207-yjaiybwf 46 19 25 25 CD cord-001207-yjaiybwf 46 20 ] ] -RRB- cord-001207-yjaiybwf 46 21 [ [ -LRB- cord-001207-yjaiybwf 46 22 26 26 CD cord-001207-yjaiybwf 46 23 ] ] -RRB- cord-001207-yjaiybwf 46 24 [ [ -LRB- cord-001207-yjaiybwf 46 25 27 27 CD cord-001207-yjaiybwf 46 26 ] ] -RRB- cord-001207-yjaiybwf 46 27 . . . cord-001207-yjaiybwf 47 1 Feeding feed VBG cord-001207-yjaiybwf 47 2 with with IN cord-001207-yjaiybwf 47 3 probiotic probiotic JJ cord-001207-yjaiybwf 47 4 microorganisms microorganism NNS cord-001207-yjaiybwf 47 5 such such JJ cord-001207-yjaiybwf 47 6 as as IN cord-001207-yjaiybwf 47 7 Lactobacillus lactobacillus NN cord-001207-yjaiybwf 47 8 rhamnosus rhamnosus NN cord-001207-yjaiybwf 47 9 GG GG NNP cord-001207-yjaiybwf 47 10 , , , cord-001207-yjaiybwf 47 11 Saccharomyces Saccharomyces NNP cord-001207-yjaiybwf 47 12 boulardii boulardii NNP cord-001207-yjaiybwf 47 13 or or CC cord-001207-yjaiybwf 47 14 Bifidobacterium Bifidobacterium NNP cord-001207-yjaiybwf 47 15 lactis lactis NNP cord-001207-yjaiybwf 47 16 resulted result VBD cord-001207-yjaiybwf 47 17 in in IN cord-001207-yjaiybwf 47 18 milder mild JJR cord-001207-yjaiybwf 47 19 clinical clinical JJ cord-001207-yjaiybwf 47 20 symptoms symptom NNS cord-001207-yjaiybwf 47 21 , , , cord-001207-yjaiybwf 47 22 reduced reduce VBN cord-001207-yjaiybwf 47 23 virus virus NN cord-001207-yjaiybwf 47 24 shedding shed VBG cord-001207-yjaiybwf 47 25 and and CC cord-001207-yjaiybwf 47 26 shortened shorten VBD cord-001207-yjaiybwf 47 27 the the DT cord-001207-yjaiybwf 47 28 duration duration NN cord-001207-yjaiybwf 47 29 of of IN cord-001207-yjaiybwf 47 30 diarrhoea diarrhoea NN cord-001207-yjaiybwf 47 31 in in IN cord-001207-yjaiybwf 47 32 children child NNS cord-001207-yjaiybwf 47 33 [ [ -LRB- cord-001207-yjaiybwf 47 34 27 27 CD cord-001207-yjaiybwf 47 35 ] ] -RRB- cord-001207-yjaiybwf 47 36 [ [ -LRB- cord-001207-yjaiybwf 47 37 28 28 CD cord-001207-yjaiybwf 47 38 ] ] -RRB- cord-001207-yjaiybwf 47 39 [ [ -LRB- cord-001207-yjaiybwf 47 40 29 29 CD cord-001207-yjaiybwf 47 41 ] ] -RRB- cord-001207-yjaiybwf 47 42 . . . cord-001207-yjaiybwf 48 1 In in IN cord-001207-yjaiybwf 48 2 pigs pig NNS cord-001207-yjaiybwf 48 3 , , , cord-001207-yjaiybwf 48 4 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 48 5 ( ( -LRB- cord-001207-yjaiybwf 48 6 E. E. NNP cord-001207-yjaiybwf 48 7 ) ) -RRB- cord-001207-yjaiybwf 48 8 faecium faecium NN cord-001207-yjaiybwf 48 9 NCIMB NCIMB NNP cord-001207-yjaiybwf 48 10 10415 10415 CD cord-001207-yjaiybwf 48 11 is be VBZ cord-001207-yjaiybwf 48 12 a a DT cord-001207-yjaiybwf 48 13 commonly commonly RB cord-001207-yjaiybwf 48 14 used use VBN cord-001207-yjaiybwf 48 15 probiotic probiotic JJ cord-001207-yjaiybwf 48 16 bacterium bacterium NN cord-001207-yjaiybwf 48 17 [ [ -LRB- cord-001207-yjaiybwf 48 18 35 35 CD cord-001207-yjaiybwf 48 19 , , , cord-001207-yjaiybwf 48 20 37 37 CD cord-001207-yjaiybwf 48 21 ] ] -RRB- cord-001207-yjaiybwf 48 22 . . . cord-001207-yjaiybwf 49 1 It -PRON- PRP cord-001207-yjaiybwf 49 2 has have VBZ cord-001207-yjaiybwf 49 3 been be VBN cord-001207-yjaiybwf 49 4 shown show VBN cord-001207-yjaiybwf 49 5 recently recently RB cord-001207-yjaiybwf 49 6 , , , cord-001207-yjaiybwf 49 7 that that IN cord-001207-yjaiybwf 49 8 feeding feeding NN cord-001207-yjaiybwf 49 9 of of IN cord-001207-yjaiybwf 49 10 pigs pig NNS cord-001207-yjaiybwf 49 11 with with IN cord-001207-yjaiybwf 49 12 this this DT cord-001207-yjaiybwf 49 13 probiotic probiotic JJ cord-001207-yjaiybwf 49 14 bacterium bacterium NN cord-001207-yjaiybwf 49 15 affected affect VBD cord-001207-yjaiybwf 49 16 shedding shedding NN cord-001207-yjaiybwf 49 17 of of IN cord-001207-yjaiybwf 49 18 enteric enteric JJ cord-001207-yjaiybwf 49 19 viruses virus NNS cord-001207-yjaiybwf 49 20 dependent dependent JJ cord-001207-yjaiybwf 49 21 on on IN cord-001207-yjaiybwf 49 22 the the DT cord-001207-yjaiybwf 49 23 virus virus NN cord-001207-yjaiybwf 49 24 species specie NNS cord-001207-yjaiybwf 49 25 [ [ -LRB- cord-001207-yjaiybwf 49 26 30 30 CD cord-001207-yjaiybwf 49 27 ] ] -RRB- cord-001207-yjaiybwf 49 28 . . . cord-001207-yjaiybwf 50 1 Especially especially RB cord-001207-yjaiybwf 50 2 , , , cord-001207-yjaiybwf 50 3 rotavirus rotavirus NN cord-001207-yjaiybwf 50 4 was be VBD cord-001207-yjaiybwf 50 5 shed shed VBN cord-001207-yjaiybwf 50 6 later later RB cord-001207-yjaiybwf 50 7 and and CC cord-001207-yjaiybwf 50 8 in in IN cord-001207-yjaiybwf 50 9 lower low JJR cord-001207-yjaiybwf 50 10 amounts amount NNS cord-001207-yjaiybwf 50 11 in in IN cord-001207-yjaiybwf 50 12 the the DT cord-001207-yjaiybwf 50 13 group group NN cord-001207-yjaiybwf 50 14 of of IN cord-001207-yjaiybwf 50 15 piglets piglet NNS cord-001207-yjaiybwf 50 16 that that WDT cord-001207-yjaiybwf 50 17 received receive VBD cord-001207-yjaiybwf 50 18 E. E. NNP cord-001207-yjaiybwf 50 19 faecium faecium NN cord-001207-yjaiybwf 50 20 NCIMB NCIMB NNP cord-001207-yjaiybwf 50 21 10415 10415 CD cord-001207-yjaiybwf 50 22 as as IN cord-001207-yjaiybwf 50 23 compared compare VBN cord-001207-yjaiybwf 50 24 to to IN cord-001207-yjaiybwf 50 25 the the DT cord-001207-yjaiybwf 50 26 control control NN cord-001207-yjaiybwf 50 27 group group NN cord-001207-yjaiybwf 50 28 . . . cord-001207-yjaiybwf 51 1 The the DT cord-001207-yjaiybwf 51 2 specific specific JJ cord-001207-yjaiybwf 51 3 mechanisms mechanism NNS cord-001207-yjaiybwf 51 4 responsible responsible JJ cord-001207-yjaiybwf 51 5 for for IN cord-001207-yjaiybwf 51 6 this this DT cord-001207-yjaiybwf 51 7 effect effect NN cord-001207-yjaiybwf 51 8 are be VBP cord-001207-yjaiybwf 51 9 not not RB cord-001207-yjaiybwf 51 10 known know VBN cord-001207-yjaiybwf 51 11 so so RB cord-001207-yjaiybwf 51 12 far far RB cord-001207-yjaiybwf 51 13 . . . cord-001207-yjaiybwf 52 1 However however RB cord-001207-yjaiybwf 52 2 , , , cord-001207-yjaiybwf 52 3 changes change NNS cord-001207-yjaiybwf 52 4 in in IN cord-001207-yjaiybwf 52 5 the the DT cord-001207-yjaiybwf 52 6 mucosal mucosal JJ cord-001207-yjaiybwf 52 7 and and CC cord-001207-yjaiybwf 52 8 systemic systemic JJ cord-001207-yjaiybwf 52 9 immunity immunity NN cord-001207-yjaiybwf 52 10 due due IN cord-001207-yjaiybwf 52 11 to to IN cord-001207-yjaiybwf 52 12 feeding feed VBG cord-001207-yjaiybwf 52 13 with with IN cord-001207-yjaiybwf 52 14 E. E. NNP cord-001207-yjaiybwf 52 15 faecium faecium NNP cord-001207-yjaiybwf 53 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 53 2 10415 10415 CD cord-001207-yjaiybwf 53 3 have have VBP cord-001207-yjaiybwf 53 4 been be VBN cord-001207-yjaiybwf 53 5 described describe VBN cord-001207-yjaiybwf 53 6 [ [ -LRB- cord-001207-yjaiybwf 53 7 31 31 CD cord-001207-yjaiybwf 53 8 ] ] -RRB- cord-001207-yjaiybwf 53 9 [ [ -LRB- cord-001207-yjaiybwf 53 10 32 32 CD cord-001207-yjaiybwf 53 11 ] ] -RRB- cord-001207-yjaiybwf 54 1 [ [ -LRB- cord-001207-yjaiybwf 54 2 33 33 CD cord-001207-yjaiybwf 54 3 ] ] -RRB- cord-001207-yjaiybwf 54 4 [ [ -LRB- cord-001207-yjaiybwf 54 5 34 34 CD cord-001207-yjaiybwf 54 6 ] ] -RRB- cord-001207-yjaiybwf 54 7 . . . cord-001207-yjaiybwf 55 1 In in IN cord-001207-yjaiybwf 55 2 addition addition NN cord-001207-yjaiybwf 55 3 , , , cord-001207-yjaiybwf 55 4 direct direct JJ cord-001207-yjaiybwf 55 5 interactions interaction NNS cord-001207-yjaiybwf 55 6 of of IN cord-001207-yjaiybwf 55 7 this this DT cord-001207-yjaiybwf 55 8 bacterium bacterium NN cord-001207-yjaiybwf 55 9 with with IN cord-001207-yjaiybwf 55 10 enteric enteric JJ cord-001207-yjaiybwf 55 11 virus virus NN cord-001207-yjaiybwf 55 12 particles particle NNS cord-001207-yjaiybwf 55 13 have have VBP cord-001207-yjaiybwf 55 14 been be VBN cord-001207-yjaiybwf 55 15 observed observe VBN cord-001207-yjaiybwf 55 16 in in IN cord-001207-yjaiybwf 55 17 in in FW cord-001207-yjaiybwf 55 18 vitro vitro FW cord-001207-yjaiybwf 55 19 studies study NNS cord-001207-yjaiybwf 55 20 [ [ -LRB- cord-001207-yjaiybwf 55 21 35 35 CD cord-001207-yjaiybwf 55 22 ] ] -RRB- cord-001207-yjaiybwf 55 23 . . . cord-001207-yjaiybwf 56 1 However however RB cord-001207-yjaiybwf 56 2 , , , cord-001207-yjaiybwf 56 3 it -PRON- PRP cord-001207-yjaiybwf 56 4 is be VBZ cord-001207-yjaiybwf 56 5 not not RB cord-001207-yjaiybwf 56 6 known know VBN cord-001207-yjaiybwf 56 7 so so RB cord-001207-yjaiybwf 56 8 far far RB cord-001207-yjaiybwf 56 9 , , , cord-001207-yjaiybwf 56 10 whether whether IN cord-001207-yjaiybwf 56 11 probiotic probiotic JJ cord-001207-yjaiybwf 56 12 bacteria bacteria NNS cord-001207-yjaiybwf 56 13 can can MD cord-001207-yjaiybwf 56 14 also also RB cord-001207-yjaiybwf 56 15 influence influence VB cord-001207-yjaiybwf 56 16 the the DT cord-001207-yjaiybwf 56 17 general general JJ cord-001207-yjaiybwf 56 18 composition composition NN cord-001207-yjaiybwf 56 19 of of IN cord-001207-yjaiybwf 56 20 the the DT cord-001207-yjaiybwf 56 21 faecal faecal JJ cord-001207-yjaiybwf 56 22 virome virome NN cord-001207-yjaiybwf 56 23 , , , cord-001207-yjaiybwf 56 24 e.g. e.g. RB cord-001207-yjaiybwf 56 25 by by IN cord-001207-yjaiybwf 56 26 changing change VBG cord-001207-yjaiybwf 56 27 the the DT cord-001207-yjaiybwf 56 28 composition composition NN cord-001207-yjaiybwf 56 29 of of IN cord-001207-yjaiybwf 56 30 the the DT cord-001207-yjaiybwf 56 31 bacterial bacterial JJ cord-001207-yjaiybwf 56 32 community community NN cord-001207-yjaiybwf 56 33 , , , cord-001207-yjaiybwf 56 34 which which WDT cord-001207-yjaiybwf 56 35 represents represent VBZ cord-001207-yjaiybwf 56 36 the the DT cord-001207-yjaiybwf 56 37 host host NN cord-001207-yjaiybwf 56 38 population population NN cord-001207-yjaiybwf 56 39 for for IN cord-001207-yjaiybwf 56 40 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 56 41 , , , cord-001207-yjaiybwf 56 42 or or CC cord-001207-yjaiybwf 56 43 by by IN cord-001207-yjaiybwf 56 44 direct direct JJ cord-001207-yjaiybwf 56 45 interactions interaction NNS cord-001207-yjaiybwf 56 46 with with IN cord-001207-yjaiybwf 56 47 specific specific JJ cord-001207-yjaiybwf 56 48 viruses virus NNS cord-001207-yjaiybwf 56 49 . . . cord-001207-yjaiybwf 57 1 The the DT cord-001207-yjaiybwf 57 2 primary primary JJ cord-001207-yjaiybwf 57 3 aim aim NN cord-001207-yjaiybwf 57 4 of of IN cord-001207-yjaiybwf 57 5 the the DT cord-001207-yjaiybwf 57 6 presented present VBN cord-001207-yjaiybwf 57 7 study study NN cord-001207-yjaiybwf 57 8 was be VBD cord-001207-yjaiybwf 57 9 to to TO cord-001207-yjaiybwf 57 10 analyze analyze VB cord-001207-yjaiybwf 57 11 the the DT cord-001207-yjaiybwf 57 12 effect effect NN cord-001207-yjaiybwf 57 13 of of IN cord-001207-yjaiybwf 57 14 the the DT cord-001207-yjaiybwf 57 15 probiotic probiotic JJ cord-001207-yjaiybwf 57 16 bacterium bacterium NN cord-001207-yjaiybwf 57 17 E. E. NNP cord-001207-yjaiybwf 57 18 faecium faecium NN cord-001207-yjaiybwf 58 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 58 2 10415 10415 CD cord-001207-yjaiybwf 58 3 on on IN cord-001207-yjaiybwf 58 4 the the DT cord-001207-yjaiybwf 58 5 general general JJ cord-001207-yjaiybwf 58 6 composition composition NN cord-001207-yjaiybwf 58 7 of of IN cord-001207-yjaiybwf 58 8 the the DT cord-001207-yjaiybwf 58 9 faecal faecal JJ cord-001207-yjaiybwf 58 10 virome virome NN cord-001207-yjaiybwf 58 11 in in IN cord-001207-yjaiybwf 58 12 pigs pig NNS cord-001207-yjaiybwf 58 13 . . . cord-001207-yjaiybwf 59 1 Faecal Faecal NNP cord-001207-yjaiybwf 59 2 samples sample NNS cord-001207-yjaiybwf 59 3 from from IN cord-001207-yjaiybwf 59 4 sows sow NNS cord-001207-yjaiybwf 59 5 and and CC cord-001207-yjaiybwf 59 6 their -PRON- PRP$ cord-001207-yjaiybwf 59 7 piglets piglet NNS cord-001207-yjaiybwf 59 8 experimentally experimentally RB cord-001207-yjaiybwf 59 9 fed feed VBD cord-001207-yjaiybwf 59 10 with with IN cord-001207-yjaiybwf 59 11 or or CC cord-001207-yjaiybwf 59 12 without without IN cord-001207-yjaiybwf 59 13 the the DT cord-001207-yjaiybwf 59 14 probiotic probiotic JJ cord-001207-yjaiybwf 59 15 bacterium bacterium NN cord-001207-yjaiybwf 59 16 were be VBD cord-001207-yjaiybwf 59 17 analyzed analyze VBN cord-001207-yjaiybwf 59 18 using use VBG cord-001207-yjaiybwf 59 19 a a DT cord-001207-yjaiybwf 59 20 process process NN cord-001207-yjaiybwf 59 21 - - HYPH cord-001207-yjaiybwf 59 22 controlled control VBN cord-001207-yjaiybwf 59 23 deep deep JJ cord-001207-yjaiybwf 59 24 sequencing sequencing NN cord-001207-yjaiybwf 59 25 method method NN cord-001207-yjaiybwf 59 26 . . . cord-001207-yjaiybwf 60 1 The the DT cord-001207-yjaiybwf 60 2 populations population NNS cord-001207-yjaiybwf 60 3 of of IN cord-001207-yjaiybwf 60 4 the the DT cord-001207-yjaiybwf 60 5 detected detect VBN cord-001207-yjaiybwf 60 6 virus virus NN cord-001207-yjaiybwf 60 7 sequences sequence NNS cord-001207-yjaiybwf 60 8 were be VBD cord-001207-yjaiybwf 60 9 compared compare VBN cord-001207-yjaiybwf 60 10 between between IN cord-001207-yjaiybwf 60 11 the the DT cord-001207-yjaiybwf 60 12 feeding feed VBG cord-001207-yjaiybwf 60 13 groups group NNS cord-001207-yjaiybwf 60 14 as as RB cord-001207-yjaiybwf 60 15 well well RB cord-001207-yjaiybwf 60 16 as as IN cord-001207-yjaiybwf 60 17 the the DT cord-001207-yjaiybwf 60 18 age age NN cord-001207-yjaiybwf 60 19 groups group NNS cord-001207-yjaiybwf 60 20 and and CC cord-001207-yjaiybwf 60 21 general general JJ cord-001207-yjaiybwf 60 22 insights insight NNS cord-001207-yjaiybwf 60 23 into into IN cord-001207-yjaiybwf 60 24 the the DT cord-001207-yjaiybwf 60 25 stability stability NN cord-001207-yjaiybwf 60 26 and and CC cord-001207-yjaiybwf 60 27 dynamics dynamic NNS cord-001207-yjaiybwf 60 28 of of IN cord-001207-yjaiybwf 60 29 the the DT cord-001207-yjaiybwf 60 30 pig pig NN cord-001207-yjaiybwf 60 31 faecal faecal JJ cord-001207-yjaiybwf 60 32 virome virome NNP cord-001207-yjaiybwf 60 33 under under IN cord-001207-yjaiybwf 60 34 different different JJ cord-001207-yjaiybwf 60 35 age age NN cord-001207-yjaiybwf 60 36 - - HYPH cord-001207-yjaiybwf 60 37 related relate VBN cord-001207-yjaiybwf 60 38 and and CC cord-001207-yjaiybwf 60 39 feeding feeding NN cord-001207-yjaiybwf 60 40 conditions condition NNS cord-001207-yjaiybwf 60 41 were be VBD cord-001207-yjaiybwf 60 42 generated generate VBN cord-001207-yjaiybwf 60 43 . . . cord-001207-yjaiybwf 61 1 The the DT cord-001207-yjaiybwf 61 2 animal animal NN cord-001207-yjaiybwf 61 3 experiment experiment NN cord-001207-yjaiybwf 61 4 ( ( -LRB- cord-001207-yjaiybwf 61 5 pig pig NN cord-001207-yjaiybwf 61 6 feeding feed VBG cord-001207-yjaiybwf 61 7 trial trial NN cord-001207-yjaiybwf 61 8 ) ) -RRB- cord-001207-yjaiybwf 61 9 was be VBD cord-001207-yjaiybwf 61 10 approved approve VBN cord-001207-yjaiybwf 61 11 by by IN cord-001207-yjaiybwf 61 12 the the DT cord-001207-yjaiybwf 61 13 local local JJ cord-001207-yjaiybwf 61 14 state state NN cord-001207-yjaiybwf 61 15 office office NNP cord-001207-yjaiybwf 61 16 of of IN cord-001207-yjaiybwf 61 17 occupational occupational NNP cord-001207-yjaiybwf 61 18 health health NNP cord-001207-yjaiybwf 61 19 and and CC cord-001207-yjaiybwf 61 20 technical technical JJ cord-001207-yjaiybwf 61 21 safety safety NN cord-001207-yjaiybwf 61 22 '' '' '' cord-001207-yjaiybwf 62 1 Landesamt Landesamt NNP cord-001207-yjaiybwf 62 2 für für IN cord-001207-yjaiybwf 62 3 Gesundheit Gesundheit NNP cord-001207-yjaiybwf 62 4 und und IN cord-001207-yjaiybwf 62 5 Soziales Soziales NNP cord-001207-yjaiybwf 62 6 Berlin Berlin NNP cord-001207-yjaiybwf 62 7 ' ' '' cord-001207-yjaiybwf 62 8 ' ' '' cord-001207-yjaiybwf 62 9 ( ( -LRB- cord-001207-yjaiybwf 62 10 LaGeSo LaGeSo NNP cord-001207-yjaiybwf 62 11 Reg Reg NNP cord-001207-yjaiybwf 62 12 . . . cord-001207-yjaiybwf 63 1 Nr Nr NNP cord-001207-yjaiybwf 63 2 . . NNP cord-001207-yjaiybwf 63 3 0347/09 0347/09 CD cord-001207-yjaiybwf 63 4 ) ) -RRB- cord-001207-yjaiybwf 63 5 . . . cord-001207-yjaiybwf 64 1 Animal Animal NNP cord-001207-yjaiybwf 64 2 Experiment Experiment NNP cord-001207-yjaiybwf 64 3 and and CC cord-001207-yjaiybwf 64 4 Sampling Sampling NNP cord-001207-yjaiybwf 64 5 Scheme Scheme NNP cord-001207-yjaiybwf 65 1 The the DT cord-001207-yjaiybwf 65 2 design design NN cord-001207-yjaiybwf 65 3 of of IN cord-001207-yjaiybwf 65 4 the the DT cord-001207-yjaiybwf 65 5 pig pig NN cord-001207-yjaiybwf 65 6 feeding feed VBG cord-001207-yjaiybwf 65 7 trial trial NN cord-001207-yjaiybwf 65 8 has have VBZ cord-001207-yjaiybwf 65 9 been be VBN cord-001207-yjaiybwf 65 10 described describe VBN cord-001207-yjaiybwf 65 11 in in IN cord-001207-yjaiybwf 65 12 detail detail NN cord-001207-yjaiybwf 65 13 by by IN cord-001207-yjaiybwf 65 14 Martin Martin NNP cord-001207-yjaiybwf 65 15 et et NNP cord-001207-yjaiybwf 65 16 al al NNP cord-001207-yjaiybwf 65 17 . . . cord-001207-yjaiybwf 66 1 [ [ -LRB- cord-001207-yjaiybwf 66 2 36 36 CD cord-001207-yjaiybwf 66 3 ] ] -RRB- cord-001207-yjaiybwf 66 4 and and CC cord-001207-yjaiybwf 66 5 is be VBZ cord-001207-yjaiybwf 66 6 schematically schematically RB cord-001207-yjaiybwf 66 7 shown show VBN cord-001207-yjaiybwf 66 8 in in IN cord-001207-yjaiybwf 66 9 Figure figure NN cord-001207-yjaiybwf 66 10 1 1 CD cord-001207-yjaiybwf 66 11 . . . cord-001207-yjaiybwf 67 1 Briefly briefly RB cord-001207-yjaiybwf 67 2 , , , cord-001207-yjaiybwf 67 3 sows sow NNS cord-001207-yjaiybwf 67 4 and and CC cord-001207-yjaiybwf 67 5 their -PRON- PRP$ cord-001207-yjaiybwf 67 6 piglets piglet NNS cord-001207-yjaiybwf 67 7 received receive VBD cord-001207-yjaiybwf 67 8 either either CC cord-001207-yjaiybwf 67 9 no no DT cord-001207-yjaiybwf 67 10 probiotic probiotic JJ cord-001207-yjaiybwf 67 11 bacterium bacterium NN cord-001207-yjaiybwf 67 12 or or CC cord-001207-yjaiybwf 67 13 approximately approximately RB cord-001207-yjaiybwf 67 14 5610 5610 CD cord-001207-yjaiybwf 67 15 6 6 CD cord-001207-yjaiybwf 67 16 cfu cfu NNP cord-001207-yjaiybwf 67 17 / / SYM cord-001207-yjaiybwf 67 18 g g NNP cord-001207-yjaiybwf 67 19 E. E. NNP cord-001207-yjaiybwf 67 20 faecium faecium NN cord-001207-yjaiybwf 67 21 NCIMB NCIMB NNP cord-001207-yjaiybwf 67 22 10415 10415 CD cord-001207-yjaiybwf 67 23 , , , cord-001207-yjaiybwf 67 24 which which WDT cord-001207-yjaiybwf 67 25 was be VBD cord-001207-yjaiybwf 67 26 fed feed VBN cord-001207-yjaiybwf 67 27 with with IN cord-001207-yjaiybwf 67 28 their -PRON- PRP$ cord-001207-yjaiybwf 67 29 diet diet NN cord-001207-yjaiybwf 67 30 starting start VBG cord-001207-yjaiybwf 67 31 at at IN cord-001207-yjaiybwf 67 32 28 28 CD cord-001207-yjaiybwf 67 33 days day NNS cord-001207-yjaiybwf 67 34 ante ante NNP cord-001207-yjaiybwf 67 35 partum partum NNP cord-001207-yjaiybwf 67 36 . . . cord-001207-yjaiybwf 68 1 The the DT cord-001207-yjaiybwf 68 2 sows sow NNS cord-001207-yjaiybwf 68 3 received receive VBD cord-001207-yjaiybwf 68 4 a a DT cord-001207-yjaiybwf 68 5 commercial commercial JJ cord-001207-yjaiybwf 68 6 diet diet NN cord-001207-yjaiybwf 68 7 ( ( -LRB- cord-001207-yjaiybwf 68 8 UNA UNA NNP cord-001207-yjaiybwf 68 9 - - HYPH cord-001207-yjaiybwf 68 10 HAKRA HAKRA NNP cord-001207-yjaiybwf 68 11 , , , cord-001207-yjaiybwf 68 12 Hamburg Hamburg NNP cord-001207-yjaiybwf 68 13 , , , cord-001207-yjaiybwf 68 14 Germany Germany NNP cord-001207-yjaiybwf 68 15 ) ) -RRB- cord-001207-yjaiybwf 68 16 . . . cord-001207-yjaiybwf 69 1 Additional additional JJ cord-001207-yjaiybwf 69 2 feeding feeding NN cord-001207-yjaiybwf 69 3 of of IN cord-001207-yjaiybwf 69 4 the the DT cord-001207-yjaiybwf 69 5 piglets piglet NNS cord-001207-yjaiybwf 69 6 started start VBD cord-001207-yjaiybwf 69 7 at at IN cord-001207-yjaiybwf 69 8 12 12 CD cord-001207-yjaiybwf 69 9 days day NNS cord-001207-yjaiybwf 69 10 of of IN cord-001207-yjaiybwf 69 11 age age NN cord-001207-yjaiybwf 69 12 with with IN cord-001207-yjaiybwf 69 13 a a DT cord-001207-yjaiybwf 69 14 non non JJ cord-001207-yjaiybwf 69 15 - - JJ cord-001207-yjaiybwf 69 16 medicated medicated JJ cord-001207-yjaiybwf 69 17 non non JJ cord-001207-yjaiybwf 69 18 - - JJ cord-001207-yjaiybwf 69 19 commercial commercial JJ cord-001207-yjaiybwf 69 20 pre pre JJ cord-001207-yjaiybwf 69 21 - - JJ cord-001207-yjaiybwf 69 22 starter starter JJ cord-001207-yjaiybwf 69 23 diet diet NN cord-001207-yjaiybwf 69 24 [ [ -LRB- cord-001207-yjaiybwf 69 25 36 36 CD cord-001207-yjaiybwf 69 26 ] ] -RRB- cord-001207-yjaiybwf 69 27 . . . cord-001207-yjaiybwf 70 1 After after IN cord-001207-yjaiybwf 70 2 weaning wean VBG cord-001207-yjaiybwf 70 3 at at IN cord-001207-yjaiybwf 70 4 28 28 CD cord-001207-yjaiybwf 70 5 days day NNS cord-001207-yjaiybwf 70 6 of of IN cord-001207-yjaiybwf 70 7 age age NN cord-001207-yjaiybwf 70 8 , , , cord-001207-yjaiybwf 70 9 they -PRON- PRP cord-001207-yjaiybwf 70 10 were be VBD cord-001207-yjaiybwf 70 11 fed feed VBN cord-001207-yjaiybwf 70 12 with with IN cord-001207-yjaiybwf 70 13 a a DT cord-001207-yjaiybwf 70 14 non non JJ cord-001207-yjaiybwf 70 15 - - JJ cord-001207-yjaiybwf 70 16 commercial commercial JJ cord-001207-yjaiybwf 70 17 mash mash NN cord-001207-yjaiybwf 70 18 starter starter NN cord-001207-yjaiybwf 70 19 diet diet NN cord-001207-yjaiybwf 70 20 [ [ -LRB- cord-001207-yjaiybwf 70 21 37 37 CD cord-001207-yjaiybwf 70 22 ] ] -RRB- cord-001207-yjaiybwf 70 23 . . . cord-001207-yjaiybwf 71 1 The the DT cord-001207-yjaiybwf 71 2 homogenous homogenous JJ cord-001207-yjaiybwf 71 3 distribution distribution NN cord-001207-yjaiybwf 71 4 of of IN cord-001207-yjaiybwf 71 5 the the DT cord-001207-yjaiybwf 71 6 probiotic probiotic NN cord-001207-yjaiybwf 71 7 in in IN cord-001207-yjaiybwf 71 8 feed feed NN cord-001207-yjaiybwf 71 9 has have VBZ cord-001207-yjaiybwf 71 10 been be VBN cord-001207-yjaiybwf 71 11 previously previously RB cord-001207-yjaiybwf 71 12 demonstrated demonstrate VBN cord-001207-yjaiybwf 71 13 by by IN cord-001207-yjaiybwf 71 14 a a DT cord-001207-yjaiybwf 71 15 colony colony NN cord-001207-yjaiybwf 71 16 hybridization hybridization NN cord-001207-yjaiybwf 71 17 assay assay NN cord-001207-yjaiybwf 71 18 [ [ -LRB- cord-001207-yjaiybwf 71 19 37 37 CD cord-001207-yjaiybwf 71 20 ] ] -RRB- cord-001207-yjaiybwf 71 21 . . . cord-001207-yjaiybwf 72 1 The the DT cord-001207-yjaiybwf 72 2 faeces faece NNS cord-001207-yjaiybwf 72 3 of of IN cord-001207-yjaiybwf 72 4 6 6 CD cord-001207-yjaiybwf 72 5 sows sow NNS cord-001207-yjaiybwf 72 6 of of IN cord-001207-yjaiybwf 72 7 each each DT cord-001207-yjaiybwf 72 8 group group NN cord-001207-yjaiybwf 72 9 were be VBD cord-001207-yjaiybwf 72 10 sampled sample VBN cord-001207-yjaiybwf 72 11 at at IN cord-001207-yjaiybwf 72 12 day day NN cord-001207-yjaiybwf 72 13 28 28 CD cord-001207-yjaiybwf 72 14 ante ante NN cord-001207-yjaiybwf 72 15 partum partum NNP cord-001207-yjaiybwf 72 16 ( ( -LRB- cord-001207-yjaiybwf 72 17 before before IN cord-001207-yjaiybwf 72 18 E. E. NNP cord-001207-yjaiybwf 72 19 faecium faecium NN cord-001207-yjaiybwf 72 20 diet diet NN cord-001207-yjaiybwf 72 21 ) ) -RRB- cord-001207-yjaiybwf 72 22 and and CC cord-001207-yjaiybwf 72 23 at at IN cord-001207-yjaiybwf 72 24 day day NN cord-001207-yjaiybwf 72 25 14 14 CD cord-001207-yjaiybwf 72 26 post post NN cord-001207-yjaiybwf 72 27 partum partum NN cord-001207-yjaiybwf 72 28 . . . cord-001207-yjaiybwf 73 1 Faeces faece NNS cord-001207-yjaiybwf 73 2 of of IN cord-001207-yjaiybwf 73 3 their -PRON- PRP$ cord-001207-yjaiybwf 73 4 piglets piglet NNS cord-001207-yjaiybwf 73 5 ( ( -LRB- cord-001207-yjaiybwf 73 6 6 6 CD cord-001207-yjaiybwf 73 7 from from IN cord-001207-yjaiybwf 73 8 each each DT cord-001207-yjaiybwf 73 9 group group NN cord-001207-yjaiybwf 73 10 ) ) -RRB- cord-001207-yjaiybwf 73 11 were be VBD cord-001207-yjaiybwf 73 12 collected collect VBN cord-001207-yjaiybwf 73 13 at at IN cord-001207-yjaiybwf 73 14 day day NN cord-001207-yjaiybwf 73 15 12 12 CD cord-001207-yjaiybwf 73 16 and and CC cord-001207-yjaiybwf 73 17 at at IN cord-001207-yjaiybwf 73 18 day day NN cord-001207-yjaiybwf 73 19 54 54 CD cord-001207-yjaiybwf 73 20 of of IN cord-001207-yjaiybwf 73 21 age age NN cord-001207-yjaiybwf 73 22 ( ( -LRB- cord-001207-yjaiybwf 73 23 end end NN cord-001207-yjaiybwf 73 24 of of IN cord-001207-yjaiybwf 73 25 the the DT cord-001207-yjaiybwf 73 26 experiment experiment NN cord-001207-yjaiybwf 73 27 ) ) -RRB- cord-001207-yjaiybwf 73 28 . . . cord-001207-yjaiybwf 74 1 Piglets piglet NNS cord-001207-yjaiybwf 74 2 were be VBD cord-001207-yjaiybwf 74 3 euthanized euthanize VBN cord-001207-yjaiybwf 74 4 at at IN cord-001207-yjaiybwf 74 5 the the DT cord-001207-yjaiybwf 74 6 end end NN cord-001207-yjaiybwf 74 7 of of IN cord-001207-yjaiybwf 74 8 the the DT cord-001207-yjaiybwf 74 9 experiment experiment NN cord-001207-yjaiybwf 74 10 by by IN cord-001207-yjaiybwf 74 11 intracardial intracardial JJ cord-001207-yjaiybwf 74 12 injection injection NN cord-001207-yjaiybwf 74 13 of of IN cord-001207-yjaiybwf 74 14 a a DT cord-001207-yjaiybwf 74 15 lethal lethal JJ cord-001207-yjaiybwf 74 16 dose dose NN cord-001207-yjaiybwf 74 17 of of IN cord-001207-yjaiybwf 74 18 tetracaine tetracaine NN cord-001207-yjaiybwf 74 19 hydrochloride hydrochloride NN cord-001207-yjaiybwf 74 20 , , , cord-001207-yjaiybwf 74 21 mebezonium mebezonium NN cord-001207-yjaiybwf 74 22 iodide iodide NN cord-001207-yjaiybwf 74 23 and and CC cord-001207-yjaiybwf 74 24 embutramide embutramide NNP cord-001207-yjaiybwf 74 25 ( ( -LRB- cord-001207-yjaiybwf 74 26 T61 T61 NNP cord-001207-yjaiybwf 74 27 , , , cord-001207-yjaiybwf 74 28 Intervet Intervet NNP cord-001207-yjaiybwf 74 29 , , , cord-001207-yjaiybwf 74 30 Unterschleißheim Unterschleißheim NNP cord-001207-yjaiybwf 74 31 , , , cord-001207-yjaiybwf 74 32 Germany Germany NNP cord-001207-yjaiybwf 74 33 ) ) -RRB- cord-001207-yjaiybwf 74 34 . . . cord-001207-yjaiybwf 75 1 Although although IN cord-001207-yjaiybwf 75 2 the the DT cord-001207-yjaiybwf 75 3 whole whole JJ cord-001207-yjaiybwf 75 4 experiment experiment NN cord-001207-yjaiybwf 75 5 included include VBD cord-001207-yjaiybwf 75 6 a a DT cord-001207-yjaiybwf 75 7 larger large JJR cord-001207-yjaiybwf 75 8 number number NN cord-001207-yjaiybwf 75 9 of of IN cord-001207-yjaiybwf 75 10 animals animal NNS cord-001207-yjaiybwf 75 11 [ [ -LRB- cord-001207-yjaiybwf 75 12 30 30 CD cord-001207-yjaiybwf 75 13 , , , cord-001207-yjaiybwf 75 14 37 37 CD cord-001207-yjaiybwf 75 15 ] ] -RRB- cord-001207-yjaiybwf 75 16 , , , cord-001207-yjaiybwf 75 17 only only RB cord-001207-yjaiybwf 75 18 faeces faece NNS cord-001207-yjaiybwf 75 19 of of IN cord-001207-yjaiybwf 75 20 piglets piglet NNS cord-001207-yjaiybwf 75 21 were be VBD cord-001207-yjaiybwf 75 22 analyzed analyze VBN cord-001207-yjaiybwf 75 23 , , , cord-001207-yjaiybwf 75 24 for for IN cord-001207-yjaiybwf 75 25 which which WDT cord-001207-yjaiybwf 75 26 the the DT cord-001207-yjaiybwf 75 27 faeces faece NNS cord-001207-yjaiybwf 75 28 of of IN cord-001207-yjaiybwf 75 29 their -PRON- PRP$ cord-001207-yjaiybwf 75 30 mother mother NN cord-001207-yjaiybwf 75 31 sows sow NNS cord-001207-yjaiybwf 75 32 had have VBD cord-001207-yjaiybwf 75 33 also also RB cord-001207-yjaiybwf 75 34 been be VBN cord-001207-yjaiybwf 75 35 analysed analyse VBN cord-001207-yjaiybwf 75 36 . . . cord-001207-yjaiybwf 76 1 The the DT cord-001207-yjaiybwf 76 2 faeces faece NNS cord-001207-yjaiybwf 76 3 of of IN cord-001207-yjaiybwf 76 4 each each DT cord-001207-yjaiybwf 76 5 group group NN cord-001207-yjaiybwf 76 6 and and CC cord-001207-yjaiybwf 76 7 time time NN cord-001207-yjaiybwf 76 8 - - HYPH cord-001207-yjaiybwf 76 9 point point NN cord-001207-yjaiybwf 76 10 were be VBD cord-001207-yjaiybwf 76 11 pooled pool VBN cord-001207-yjaiybwf 76 12 . . . cord-001207-yjaiybwf 77 1 The the DT cord-001207-yjaiybwf 77 2 samples sample NNS cord-001207-yjaiybwf 77 3 were be VBD cord-001207-yjaiybwf 77 4 stored store VBN cord-001207-yjaiybwf 77 5 at at IN cord-001207-yjaiybwf 77 6 220uC 220uc NN cord-001207-yjaiybwf 77 7 until until IN cord-001207-yjaiybwf 77 8 analysis analysis NN cord-001207-yjaiybwf 77 9 . . . cord-001207-yjaiybwf 78 1 DNA DNA NNP cord-001207-yjaiybwf 78 2 was be VBD cord-001207-yjaiybwf 78 3 extracted extract VBN cord-001207-yjaiybwf 78 4 from from IN cord-001207-yjaiybwf 78 5 faecal faecal JJ cord-001207-yjaiybwf 78 6 samples sample NNS cord-001207-yjaiybwf 78 7 and and CC cord-001207-yjaiybwf 78 8 subsequently subsequently RB cord-001207-yjaiybwf 78 9 analyzed analyze VBN cord-001207-yjaiybwf 78 10 by by IN cord-001207-yjaiybwf 78 11 real real JJ cord-001207-yjaiybwf 78 12 - - HYPH cord-001207-yjaiybwf 78 13 time time NN cord-001207-yjaiybwf 78 14 PCR pcr NN cord-001207-yjaiybwf 78 15 specific specific JJ cord-001207-yjaiybwf 78 16 for for IN cord-001207-yjaiybwf 78 17 E. E. NNP cord-001207-yjaiybwf 78 18 faecium faecium NN cord-001207-yjaiybwf 78 19 NCIMB NCIMB NNP cord-001207-yjaiybwf 78 20 10415 10415 CD cord-001207-yjaiybwf 78 21 as as IN cord-001207-yjaiybwf 78 22 previously previously RB cord-001207-yjaiybwf 78 23 described describe VBN cord-001207-yjaiybwf 78 24 [ [ -LRB- cord-001207-yjaiybwf 78 25 38 38 CD cord-001207-yjaiybwf 78 26 ] ] -RRB- cord-001207-yjaiybwf 78 27 . . . cord-001207-yjaiybwf 79 1 The the DT cord-001207-yjaiybwf 79 2 standards standard NNS cord-001207-yjaiybwf 79 3 used use VBN cord-001207-yjaiybwf 79 4 for for IN cord-001207-yjaiybwf 79 5 quantification quantification NN cord-001207-yjaiybwf 79 6 were be VBD cord-001207-yjaiybwf 79 7 prepared prepare VBN cord-001207-yjaiybwf 79 8 from from IN cord-001207-yjaiybwf 79 9 negative negative JJ cord-001207-yjaiybwf 79 10 pig pig NN cord-001207-yjaiybwf 79 11 faecal faecal JJ cord-001207-yjaiybwf 79 12 samples sample NNS cord-001207-yjaiybwf 79 13 spiked spike VBN cord-001207-yjaiybwf 79 14 with with IN cord-001207-yjaiybwf 79 15 known know VBN cord-001207-yjaiybwf 79 16 amounts amount NNS cord-001207-yjaiybwf 79 17 of of IN cord-001207-yjaiybwf 79 18 cultured cultured JJ cord-001207-yjaiybwf 79 19 E. E. NNP cord-001207-yjaiybwf 79 20 faecium faecium NN cord-001207-yjaiybwf 79 21 NCIMB NCIMB NNP cord-001207-yjaiybwf 79 22 10415 10415 CD cord-001207-yjaiybwf 79 23 cells cell NNS cord-001207-yjaiybwf 79 24 as as IN cord-001207-yjaiybwf 79 25 described describe VBN cord-001207-yjaiybwf 79 26 by by IN cord-001207-yjaiybwf 79 27 Starke Starke NNP cord-001207-yjaiybwf 79 28 et et NNP cord-001207-yjaiybwf 79 29 al al NNP cord-001207-yjaiybwf 79 30 . . . cord-001207-yjaiybwf 80 1 [ [ -LRB- cord-001207-yjaiybwf 80 2 37 37 CD cord-001207-yjaiybwf 80 3 ] ] -RRB- cord-001207-yjaiybwf 80 4 Results result NNS cord-001207-yjaiybwf 80 5 are be VBP cord-001207-yjaiybwf 80 6 expressed express VBN cord-001207-yjaiybwf 80 7 as as IN cord-001207-yjaiybwf 80 8 log log NN cord-001207-yjaiybwf 80 9 of of IN cord-001207-yjaiybwf 80 10 cell cell NN cord-001207-yjaiybwf 80 11 numbers number NNS cord-001207-yjaiybwf 80 12 per per IN cord-001207-yjaiybwf 80 13 g g NN cord-001207-yjaiybwf 80 14 faeces faece NNS cord-001207-yjaiybwf 80 15 . . . cord-001207-yjaiybwf 81 1 Three three CD cord-001207-yjaiybwf 81 2 different different JJ cord-001207-yjaiybwf 81 3 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 81 4 ( ( -LRB- cord-001207-yjaiybwf 81 5 M13 M13 NNP cord-001207-yjaiybwf 81 6 , , , cord-001207-yjaiybwf 81 7 MS2 MS2 NNP cord-001207-yjaiybwf 81 8 , , , cord-001207-yjaiybwf 81 9 T4 T4 NNP cord-001207-yjaiybwf 81 10 ) ) -RRB- cord-001207-yjaiybwf 81 11 were be VBD cord-001207-yjaiybwf 81 12 grown grow VBN cord-001207-yjaiybwf 81 13 , , , cord-001207-yjaiybwf 81 14 titrated titrate VBN cord-001207-yjaiybwf 81 15 and and CC cord-001207-yjaiybwf 81 16 used use VBN cord-001207-yjaiybwf 81 17 as as IN cord-001207-yjaiybwf 81 18 process process NN cord-001207-yjaiybwf 81 19 controls control NNS cord-001207-yjaiybwf 81 20 for for IN cord-001207-yjaiybwf 81 21 monitoring monitor VBG cord-001207-yjaiybwf 81 22 the the DT cord-001207-yjaiybwf 81 23 efficiency efficiency NN cord-001207-yjaiybwf 81 24 of of IN cord-001207-yjaiybwf 81 25 the the DT cord-001207-yjaiybwf 81 26 virome virome NNP cord-001207-yjaiybwf 81 27 analysis analysis NN cord-001207-yjaiybwf 81 28 procedure procedure NN cord-001207-yjaiybwf 81 29 as as IN cord-001207-yjaiybwf 81 30 described describe VBN cord-001207-yjaiybwf 81 31 previously previously RB cord-001207-yjaiybwf 81 32 [ [ -LRB- cord-001207-yjaiybwf 81 33 10 10 CD cord-001207-yjaiybwf 81 34 ] ] -RRB- cord-001207-yjaiybwf 81 35 . . . cord-001207-yjaiybwf 82 1 A a DT cord-001207-yjaiybwf 82 2 total total NN cord-001207-yjaiybwf 82 3 of of IN cord-001207-yjaiybwf 82 4 10 10 CD cord-001207-yjaiybwf 82 5 ml ml NNS cord-001207-yjaiybwf 82 6 of of IN cord-001207-yjaiybwf 82 7 the the DT cord-001207-yjaiybwf 82 8 bacteriophage bacteriophage NN cord-001207-yjaiybwf 82 9 mixture mixture NN cord-001207-yjaiybwf 82 10 containing contain VBG cord-001207-yjaiybwf 82 11 approximately approximately RB cord-001207-yjaiybwf 82 12 10 10 CD cord-001207-yjaiybwf 82 13 5 5 CD cord-001207-yjaiybwf 82 14 plaque plaque NN cord-001207-yjaiybwf 82 15 - - HYPH cord-001207-yjaiybwf 82 16 forming form VBG cord-001207-yjaiybwf 82 17 units unit NNS cord-001207-yjaiybwf 82 18 of of IN cord-001207-yjaiybwf 82 19 each each DT cord-001207-yjaiybwf 82 20 bacteriophage bacteriophage NN cord-001207-yjaiybwf 82 21 was be VBD cord-001207-yjaiybwf 82 22 added add VBN cord-001207-yjaiybwf 82 23 per per IN cord-001207-yjaiybwf 82 24 1 1 CD cord-001207-yjaiybwf 82 25 g g NN cord-001207-yjaiybwf 82 26 faeces faece NNS cord-001207-yjaiybwf 82 27 . . . cord-001207-yjaiybwf 83 1 Virus virus NN cord-001207-yjaiybwf 83 2 particles particle NNS cord-001207-yjaiybwf 83 3 were be VBD cord-001207-yjaiybwf 83 4 purified purify VBN cord-001207-yjaiybwf 83 5 from from IN cord-001207-yjaiybwf 83 6 the the DT cord-001207-yjaiybwf 83 7 faecal faecal JJ cord-001207-yjaiybwf 83 8 samples sample NNS cord-001207-yjaiybwf 83 9 by by IN cord-001207-yjaiybwf 83 10 a a DT cord-001207-yjaiybwf 83 11 combination combination NN cord-001207-yjaiybwf 83 12 of of IN cord-001207-yjaiybwf 83 13 tangential tangential JJ cord-001207-yjaiybwf 83 14 flow flow NN cord-001207-yjaiybwf 83 15 filtration filtration NN cord-001207-yjaiybwf 83 16 ( ( -LRB- cord-001207-yjaiybwf 83 17 TFF TFF NNP cord-001207-yjaiybwf 83 18 ) ) -RRB- cord-001207-yjaiybwf 83 19 and and CC cord-001207-yjaiybwf 83 20 caesium caesium NN cord-001207-yjaiybwf 83 21 chloride chloride NN cord-001207-yjaiybwf 83 22 ( ( -LRB- cord-001207-yjaiybwf 83 23 CsCl CsCl NNP cord-001207-yjaiybwf 83 24 ) ) -RRB- cord-001207-yjaiybwf 83 25 density density NN cord-001207-yjaiybwf 83 26 gradient gradient NN cord-001207-yjaiybwf 83 27 ultracentrifugation ultracentrifugation NN cord-001207-yjaiybwf 83 28 , , , cord-001207-yjaiybwf 83 29 and and CC cord-001207-yjaiybwf 83 30 concentrated concentrate VBN cord-001207-yjaiybwf 83 31 by by IN cord-001207-yjaiybwf 83 32 centrifugal centrifugal JJ cord-001207-yjaiybwf 83 33 filtration filtration NN cord-001207-yjaiybwf 83 34 and and CC cord-001207-yjaiybwf 83 35 TFF TFF NNP cord-001207-yjaiybwf 83 36 as as IN cord-001207-yjaiybwf 83 37 described describe VBN cord-001207-yjaiybwf 83 38 [ [ -LRB- cord-001207-yjaiybwf 83 39 10 10 CD cord-001207-yjaiybwf 83 40 , , , cord-001207-yjaiybwf 83 41 39 39 CD cord-001207-yjaiybwf 83 42 ] ] -RRB- cord-001207-yjaiybwf 83 43 . . . cord-001207-yjaiybwf 84 1 A a DT cord-001207-yjaiybwf 84 2 total total NN cord-001207-yjaiybwf 84 3 of of IN cord-001207-yjaiybwf 84 4 17 17 CD cord-001207-yjaiybwf 84 5 g g NN cord-001207-yjaiybwf 84 6 of of IN cord-001207-yjaiybwf 84 7 pooled pool VBN cord-001207-yjaiybwf 84 8 faecal faecal JJ cord-001207-yjaiybwf 84 9 samples sample NNS cord-001207-yjaiybwf 84 10 from from IN cord-001207-yjaiybwf 84 11 the the DT cord-001207-yjaiybwf 84 12 sows sow NNS cord-001207-yjaiybwf 84 13 were be VBD cord-001207-yjaiybwf 84 14 used use VBN cord-001207-yjaiybwf 84 15 . . . cord-001207-yjaiybwf 85 1 Due due IN cord-001207-yjaiybwf 85 2 to to IN cord-001207-yjaiybwf 85 3 limited limited JJ cord-001207-yjaiybwf 85 4 availability availability NN cord-001207-yjaiybwf 85 5 of of IN cord-001207-yjaiybwf 85 6 faeces faece NNS cord-001207-yjaiybwf 85 7 in in IN cord-001207-yjaiybwf 85 8 the the DT cord-001207-yjaiybwf 85 9 youngest young JJS cord-001207-yjaiybwf 85 10 age age NN cord-001207-yjaiybwf 85 11 group group NN cord-001207-yjaiybwf 85 12 , , , cord-001207-yjaiybwf 85 13 1.7 1.7 CD cord-001207-yjaiybwf 85 14 g g NN cord-001207-yjaiybwf 85 15 of of IN cord-001207-yjaiybwf 85 16 the the DT cord-001207-yjaiybwf 85 17 pooled pool VBN cord-001207-yjaiybwf 85 18 faecal faecal JJ cord-001207-yjaiybwf 85 19 samples sample NNS cord-001207-yjaiybwf 85 20 from from IN cord-001207-yjaiybwf 85 21 the the DT cord-001207-yjaiybwf 85 22 piglets piglet NNS cord-001207-yjaiybwf 85 23 was be VBD cord-001207-yjaiybwf 85 24 used use VBN cord-001207-yjaiybwf 85 25 . . . cord-001207-yjaiybwf 86 1 The the DT cord-001207-yjaiybwf 86 2 samples sample NNS cord-001207-yjaiybwf 86 3 were be VBD cord-001207-yjaiybwf 86 4 spiked spike VBN cord-001207-yjaiybwf 86 5 with with IN cord-001207-yjaiybwf 86 6 test test NN cord-001207-yjaiybwf 86 7 - - HYPH cord-001207-yjaiybwf 86 8 phages phage NNS cord-001207-yjaiybwf 86 9 and and CC cord-001207-yjaiybwf 86 10 resuspended resuspended JJ cord-001207-yjaiybwf 86 11 1:10 1:10 CD cord-001207-yjaiybwf 86 12 in in IN cord-001207-yjaiybwf 86 13 SMbuffer SMbuffer NNP cord-001207-yjaiybwf 86 14 ( ( -LRB- cord-001207-yjaiybwf 86 15 100 100 CD cord-001207-yjaiybwf 86 16 mM mm CD cord-001207-yjaiybwf 86 17 NaCl nacl NN cord-001207-yjaiybwf 86 18 , , , cord-001207-yjaiybwf 87 1 8 8 CD cord-001207-yjaiybwf 87 2 mM mm CD cord-001207-yjaiybwf 87 3 MgSO MgSO NNP cord-001207-yjaiybwf 87 4 4 4 CD cord-001207-yjaiybwf 87 5 , , , cord-001207-yjaiybwf 87 6 50 50 CD cord-001207-yjaiybwf 87 7 mM mm CD cord-001207-yjaiybwf 87 8 Tris Tris NNP cord-001207-yjaiybwf 87 9 - - HYPH cord-001207-yjaiybwf 87 10 HCl HCl NNP cord-001207-yjaiybwf 87 11 pH pH NNP cord-001207-yjaiybwf 87 12 7.5 7.5 CD cord-001207-yjaiybwf 87 13 ) ) -RRB- cord-001207-yjaiybwf 87 14 by by IN cord-001207-yjaiybwf 87 15 magnetic magnetic JJ cord-001207-yjaiybwf 87 16 stirring stirring NN cord-001207-yjaiybwf 87 17 . . . cord-001207-yjaiybwf 88 1 The the DT cord-001207-yjaiybwf 88 2 sample sample NN cord-001207-yjaiybwf 88 3 was be VBD cord-001207-yjaiybwf 88 4 centrifuged centrifuge VBN cord-001207-yjaiybwf 88 5 at at IN cord-001207-yjaiybwf 88 6 10,000 10,000 CD cord-001207-yjaiybwf 88 7 g g NN cord-001207-yjaiybwf 88 8 for for IN cord-001207-yjaiybwf 88 9 30 30 CD cord-001207-yjaiybwf 88 10 min min NN cord-001207-yjaiybwf 88 11 in in IN cord-001207-yjaiybwf 88 12 order order NN cord-001207-yjaiybwf 88 13 to to TO cord-001207-yjaiybwf 88 14 remove remove VB cord-001207-yjaiybwf 88 15 the the DT cord-001207-yjaiybwf 88 16 large large JJ cord-001207-yjaiybwf 88 17 particulate particulate NN cord-001207-yjaiybwf 88 18 debris debris NN cord-001207-yjaiybwf 88 19 and and CC cord-001207-yjaiybwf 88 20 the the DT cord-001207-yjaiybwf 88 21 supernatant supernatant NN cord-001207-yjaiybwf 88 22 was be VBD cord-001207-yjaiybwf 88 23 collected collect VBN cord-001207-yjaiybwf 88 24 . . . cord-001207-yjaiybwf 89 1 The the DT cord-001207-yjaiybwf 89 2 procedure procedure NN cord-001207-yjaiybwf 89 3 was be VBD cord-001207-yjaiybwf 89 4 repeated repeat VBN cord-001207-yjaiybwf 89 5 by by IN cord-001207-yjaiybwf 89 6 centrifugation centrifugation NN cord-001207-yjaiybwf 89 7 for for IN cord-001207-yjaiybwf 89 8 3 3 CD cord-001207-yjaiybwf 89 9 hours hour NNS cord-001207-yjaiybwf 89 10 at at IN cord-001207-yjaiybwf 89 11 10,000 10,000 CD cord-001207-yjaiybwf 89 12 g g NN cord-001207-yjaiybwf 89 13 to to TO cord-001207-yjaiybwf 89 14 remove remove VB cord-001207-yjaiybwf 89 15 smaller small JJR cord-001207-yjaiybwf 89 16 particular particular JJ cord-001207-yjaiybwf 89 17 structures structure NNS cord-001207-yjaiybwf 89 18 . . . cord-001207-yjaiybwf 90 1 Afterwards afterwards RB cord-001207-yjaiybwf 90 2 , , , cord-001207-yjaiybwf 90 3 a a DT cord-001207-yjaiybwf 90 4 first first JJ cord-001207-yjaiybwf 90 5 TFF TFF NNP cord-001207-yjaiybwf 90 6 was be VBD cord-001207-yjaiybwf 90 7 performed perform VBN cord-001207-yjaiybwf 90 8 using use VBG cord-001207-yjaiybwf 90 9 a a DT cord-001207-yjaiybwf 90 10 0.22 0.22 CD cord-001207-yjaiybwf 90 11 mm mm NN cord-001207-yjaiybwf 90 12 filter filter NN cord-001207-yjaiybwf 90 13 ( ( -LRB- cord-001207-yjaiybwf 90 14 PALL PALL NNP cord-001207-yjaiybwf 90 15 Corporation Corporation NNP cord-001207-yjaiybwf 90 16 , , , cord-001207-yjaiybwf 90 17 Middleton Middleton NNP cord-001207-yjaiybwf 90 18 ; ; : cord-001207-yjaiybwf 90 19 MA MA NNP cord-001207-yjaiybwf 90 20 , , , cord-001207-yjaiybwf 90 21 USA USA NNP cord-001207-yjaiybwf 90 22 ) ) -RRB- cord-001207-yjaiybwf 90 23 to to TO cord-001207-yjaiybwf 90 24 remove remove VB cord-001207-yjaiybwf 90 25 bacterial bacterial JJ cord-001207-yjaiybwf 90 26 and and CC cord-001207-yjaiybwf 90 27 eukaryotic eukaryotic JJ cord-001207-yjaiybwf 90 28 cells cell NNS cord-001207-yjaiybwf 90 29 and and CC cord-001207-yjaiybwf 90 30 debris debris NN cord-001207-yjaiybwf 90 31 . . . cord-001207-yjaiybwf 91 1 The the DT cord-001207-yjaiybwf 91 2 remaining remain VBG cord-001207-yjaiybwf 91 3 filtrate filtrate NN cord-001207-yjaiybwf 91 4 was be VBD cord-001207-yjaiybwf 91 5 subjected subject VBN cord-001207-yjaiybwf 91 6 to to IN cord-001207-yjaiybwf 91 7 a a DT cord-001207-yjaiybwf 91 8 second second JJ cord-001207-yjaiybwf 91 9 TFF tff NN cord-001207-yjaiybwf 91 10 with with IN cord-001207-yjaiybwf 91 11 a a DT cord-001207-yjaiybwf 91 12 50 50 CD cord-001207-yjaiybwf 91 13 kDa kDa NNS cord-001207-yjaiybwf 91 14 filter filter NN cord-001207-yjaiybwf 91 15 ( ( -LRB- cord-001207-yjaiybwf 91 16 PALL PALL NNP cord-001207-yjaiybwf 91 17 Corporation Corporation NNP cord-001207-yjaiybwf 91 18 , , , cord-001207-yjaiybwf 91 19 Middleton Middleton NNP cord-001207-yjaiybwf 91 20 ; ; : cord-001207-yjaiybwf 91 21 MA MA NNP cord-001207-yjaiybwf 91 22 , , , cord-001207-yjaiybwf 91 23 USA USA NNP cord-001207-yjaiybwf 91 24 ) ) -RRB- cord-001207-yjaiybwf 91 25 in in IN cord-001207-yjaiybwf 91 26 order order NN cord-001207-yjaiybwf 91 27 to to TO cord-001207-yjaiybwf 91 28 concentrate concentrate VB cord-001207-yjaiybwf 91 29 the the DT cord-001207-yjaiybwf 91 30 virus virus NN cord-001207-yjaiybwf 91 31 particles particle NNS cord-001207-yjaiybwf 91 32 . . . cord-001207-yjaiybwf 92 1 The the DT cord-001207-yjaiybwf 92 2 viral viral JJ cord-001207-yjaiybwf 92 3 preparations preparation NNS cord-001207-yjaiybwf 92 4 were be VBD cord-001207-yjaiybwf 92 5 further further RB cord-001207-yjaiybwf 92 6 concentrated concentrate VBN cord-001207-yjaiybwf 92 7 by by IN cord-001207-yjaiybwf 92 8 centrifugation centrifugation NN cord-001207-yjaiybwf 92 9 through through IN cord-001207-yjaiybwf 92 10 Vivaspin Vivaspin NNP cord-001207-yjaiybwf 92 11 50,000 50,000 CD cord-001207-yjaiybwf 92 12 MWCO MWCO NNP cord-001207-yjaiybwf 92 13 concentrators concentrator NNS cord-001207-yjaiybwf 92 14 ( ( -LRB- cord-001207-yjaiybwf 92 15 Sartorius Sartorius NNP cord-001207-yjaiybwf 92 16 Stedim Stedim NNP cord-001207-yjaiybwf 92 17 Biotech Biotech NNP cord-001207-yjaiybwf 92 18 GmbH GmbH NNP cord-001207-yjaiybwf 92 19 , , , cord-001207-yjaiybwf 92 20 Götting Götting NNP cord-001207-yjaiybwf 92 21 , , , cord-001207-yjaiybwf 92 22 Germany Germany NNP cord-001207-yjaiybwf 92 23 ) ) -RRB- cord-001207-yjaiybwf 92 24 at at IN cord-001207-yjaiybwf 92 25 3,500 3,500 CD cord-001207-yjaiybwf 92 26 g g NN cord-001207-yjaiybwf 92 27 resulting result VBG cord-001207-yjaiybwf 92 28 in in IN cord-001207-yjaiybwf 92 29 a a DT cord-001207-yjaiybwf 92 30 final final JJ cord-001207-yjaiybwf 92 31 volume volume NN cord-001207-yjaiybwf 92 32 of of IN cord-001207-yjaiybwf 92 33 36 36 CD cord-001207-yjaiybwf 92 34 ml ml NNS cord-001207-yjaiybwf 92 35 . . . cord-001207-yjaiybwf 93 1 The the DT cord-001207-yjaiybwf 93 2 preparation preparation NN cord-001207-yjaiybwf 93 3 was be VBD cord-001207-yjaiybwf 93 4 divided divide VBN cord-001207-yjaiybwf 93 5 into into IN cord-001207-yjaiybwf 93 6 two two CD cord-001207-yjaiybwf 93 7 fractions fraction NNS cord-001207-yjaiybwf 93 8 of of IN cord-001207-yjaiybwf 93 9 18 18 CD cord-001207-yjaiybwf 93 10 ml ml NNS cord-001207-yjaiybwf 93 11 , , , cord-001207-yjaiybwf 93 12 which which WDT cord-001207-yjaiybwf 93 13 were be VBD cord-001207-yjaiybwf 93 14 added add VBN cord-001207-yjaiybwf 93 15 separately separately RB cord-001207-yjaiybwf 93 16 onto onto IN cord-001207-yjaiybwf 93 17 preformed preformed JJ cord-001207-yjaiybwf 93 18 stepwise stepwise JJ cord-001207-yjaiybwf 93 19 caesium caesium NN cord-001207-yjaiybwf 93 20 chloride chloride NN cord-001207-yjaiybwf 93 21 ( ( -LRB- cord-001207-yjaiybwf 93 22 CsCl CsCl NNP cord-001207-yjaiybwf 93 23 ) ) -RRB- cord-001207-yjaiybwf 93 24 density density NN cord-001207-yjaiybwf 93 25 gradients gradient NNS cord-001207-yjaiybwf 93 26 with with IN cord-001207-yjaiybwf 93 27 density density NN cord-001207-yjaiybwf 93 28 layers layer NNS cord-001207-yjaiybwf 93 29 of of IN cord-001207-yjaiybwf 93 30 1.7 1.7 CD cord-001207-yjaiybwf 93 31 , , , cord-001207-yjaiybwf 93 32 1.5 1.5 CD cord-001207-yjaiybwf 93 33 , , , cord-001207-yjaiybwf 93 34 1.35 1.35 CD cord-001207-yjaiybwf 93 35 and and CC cord-001207-yjaiybwf 93 36 1.2 1.2 CD cord-001207-yjaiybwf 93 37 g g NN cord-001207-yjaiybwf 93 38 / / SYM cord-001207-yjaiybwf 93 39 ml ml NN cord-001207-yjaiybwf 93 40 ( ( -LRB- cord-001207-yjaiybwf 93 41 5 5 CD cord-001207-yjaiybwf 93 42 ml ml NN cord-001207-yjaiybwf 93 43 each each DT cord-001207-yjaiybwf 93 44 ) ) -RRB- cord-001207-yjaiybwf 93 45 and and CC cord-001207-yjaiybwf 93 46 ultracentrifuged ultracentrifuge VBD cord-001207-yjaiybwf 93 47 at at IN cord-001207-yjaiybwf 93 48 20,000 20,000 CD cord-001207-yjaiybwf 93 49 g g NN cord-001207-yjaiybwf 93 50 for for IN cord-001207-yjaiybwf 93 51 14 14 CD cord-001207-yjaiybwf 93 52 hours hour NNS cord-001207-yjaiybwf 93 53 at at IN cord-001207-yjaiybwf 93 54 10uC. 10uc. CD cord-001207-yjaiybwf 94 1 The the DT cord-001207-yjaiybwf 94 2 1.35 1.35 CD cord-001207-yjaiybwf 94 3 - - SYM cord-001207-yjaiybwf 94 4 1.5 1.5 CD cord-001207-yjaiybwf 94 5 g g NN cord-001207-yjaiybwf 94 6 / / SYM cord-001207-yjaiybwf 94 7 ml ml NN cord-001207-yjaiybwf 94 8 layers layer NNS cord-001207-yjaiybwf 94 9 were be VBD cord-001207-yjaiybwf 94 10 collected collect VBN cord-001207-yjaiybwf 94 11 from from IN cord-001207-yjaiybwf 94 12 the the DT cord-001207-yjaiybwf 94 13 gradients gradient NNS cord-001207-yjaiybwf 94 14 using use VBG cord-001207-yjaiybwf 94 15 a a DT cord-001207-yjaiybwf 94 16 syringe syringe NN cord-001207-yjaiybwf 94 17 . . . cord-001207-yjaiybwf 95 1 To to TO cord-001207-yjaiybwf 95 2 eliminate eliminate VB cord-001207-yjaiybwf 95 3 free free JJ cord-001207-yjaiybwf 95 4 DNA dna NN cord-001207-yjaiybwf 95 5 present present NN cord-001207-yjaiybwf 95 6 in in IN cord-001207-yjaiybwf 95 7 the the DT cord-001207-yjaiybwf 95 8 virus virus NN cord-001207-yjaiybwf 95 9 concentrate concentrate NN cord-001207-yjaiybwf 95 10 , , , cord-001207-yjaiybwf 95 11 an an DT cord-001207-yjaiybwf 95 12 aliquot aliquot NN cord-001207-yjaiybwf 95 13 of of IN cord-001207-yjaiybwf 95 14 1 1 CD cord-001207-yjaiybwf 95 15 mL mL NNP cord-001207-yjaiybwf 95 16 CsCl CsCl NNP cord-001207-yjaiybwf 95 17 purified purify VBN cord-001207-yjaiybwf 95 18 virus virus NN cord-001207-yjaiybwf 95 19 solution solution NN cord-001207-yjaiybwf 95 20 was be VBD cord-001207-yjaiybwf 95 21 treated treat VBN cord-001207-yjaiybwf 95 22 with with IN cord-001207-yjaiybwf 95 23 50 50 CD cord-001207-yjaiybwf 95 24 units unit NNS cord-001207-yjaiybwf 96 1 DNase DNase NNP cord-001207-yjaiybwf 97 1 I -PRON- PRP cord-001207-yjaiybwf 97 2 ( ( -LRB- cord-001207-yjaiybwf 97 3 2,000 2,000 CD cord-001207-yjaiybwf 97 4 U U NNP cord-001207-yjaiybwf 97 5 / / SYM cord-001207-yjaiybwf 97 6 mg mg NN cord-001207-yjaiybwf 97 7 , , , cord-001207-yjaiybwf 97 8 bovine bovine JJ cord-001207-yjaiybwf 97 9 pancreas pancreas NN cord-001207-yjaiybwf 97 10 grad grad NN cord-001207-yjaiybwf 97 11 II II NNP cord-001207-yjaiybwf 97 12 ; ; : cord-001207-yjaiybwf 97 13 Roche Roche NNP cord-001207-yjaiybwf 97 14 Diagnostics Diagnostics NNP cord-001207-yjaiybwf 97 15 GmbH GmbH NNP cord-001207-yjaiybwf 97 16 , , , cord-001207-yjaiybwf 97 17 Mannheim Mannheim NNP cord-001207-yjaiybwf 97 18 , , , cord-001207-yjaiybwf 97 19 Germany Germany NNP cord-001207-yjaiybwf 97 20 ) ) -RRB- cord-001207-yjaiybwf 97 21 for for IN cord-001207-yjaiybwf 97 22 45 45 CD cord-001207-yjaiybwf 97 23 min min NN cord-001207-yjaiybwf 97 24 at at IN cord-001207-yjaiybwf 97 25 37uC 37uc CD cord-001207-yjaiybwf 97 26 , , , cord-001207-yjaiybwf 97 27 followed follow VBN cord-001207-yjaiybwf 97 28 by by IN cord-001207-yjaiybwf 97 29 heat heat NN cord-001207-yjaiybwf 97 30 inactivation inactivation NN cord-001207-yjaiybwf 97 31 for for IN cord-001207-yjaiybwf 97 32 10 10 CD cord-001207-yjaiybwf 97 33 min min NN cord-001207-yjaiybwf 97 34 at at IN cord-001207-yjaiybwf 97 35 65uC. 65uc. CD cord-001207-yjaiybwf 98 1 Thereafter thereafter RB cord-001207-yjaiybwf 98 2 , , , cord-001207-yjaiybwf 98 3 DNA DNA NNP cord-001207-yjaiybwf 98 4 and and CC cord-001207-yjaiybwf 98 5 RNA RNA NNP cord-001207-yjaiybwf 98 6 were be VBD cord-001207-yjaiybwf 98 7 extracted extract VBN cord-001207-yjaiybwf 98 8 simultaneously simultaneously RB cord-001207-yjaiybwf 98 9 using use VBG cord-001207-yjaiybwf 98 10 NucliSENS NucliSENS NNP cord-001207-yjaiybwf 98 11 magnetic magnetic JJ cord-001207-yjaiybwf 98 12 extraction extraction NN cord-001207-yjaiybwf 98 13 ( ( -LRB- cord-001207-yjaiybwf 98 14 bioMerieux biomerieux XX cord-001207-yjaiybwf 98 15 , , , cord-001207-yjaiybwf 98 16 Nürtingen Nürtingen NNP cord-001207-yjaiybwf 98 17 , , , cord-001207-yjaiybwf 98 18 Germany Germany NNP cord-001207-yjaiybwf 98 19 ) ) -RRB- cord-001207-yjaiybwf 98 20 . . . cord-001207-yjaiybwf 99 1 The the DT cord-001207-yjaiybwf 99 2 extracted extract VBN cord-001207-yjaiybwf 99 3 nucleic nucleic JJ cord-001207-yjaiybwf 99 4 acids acid NNS cord-001207-yjaiybwf 99 5 ( ( -LRB- cord-001207-yjaiybwf 99 6 75 75 CD cord-001207-yjaiybwf 99 7 ng ng NN cord-001207-yjaiybwf 99 8 per per IN cord-001207-yjaiybwf 99 9 reaction reaction NN cord-001207-yjaiybwf 99 10 ) ) -RRB- cord-001207-yjaiybwf 99 11 were be VBD cord-001207-yjaiybwf 99 12 randomly randomly RB cord-001207-yjaiybwf 99 13 primed prime VBN cord-001207-yjaiybwf 99 14 for for IN cord-001207-yjaiybwf 99 15 cDNA cdna NN cord-001207-yjaiybwf 99 16 synthesis synthesis NN cord-001207-yjaiybwf 99 17 using use VBG cord-001207-yjaiybwf 99 18 the the DT cord-001207-yjaiybwf 99 19 TransPlexH TransPlexH NNP cord-001207-yjaiybwf 99 20 Complete complete VB cord-001207-yjaiybwf 99 21 Whole Whole NNP cord-001207-yjaiybwf 99 22 Transcriptom Transcriptom NNP cord-001207-yjaiybwf 99 23 Amplification amplification NN cord-001207-yjaiybwf 99 24 Kit kit NN cord-001207-yjaiybwf 99 25 ( ( -LRB- cord-001207-yjaiybwf 99 26 WTA2 WTA2 NNP cord-001207-yjaiybwf 99 27 , , , cord-001207-yjaiybwf 99 28 Sigma Sigma NNP cord-001207-yjaiybwf 99 29 - - HYPH cord-001207-yjaiybwf 99 30 Aldrich Aldrich NNP cord-001207-yjaiybwf 99 31 , , , cord-001207-yjaiybwf 99 32 St. St. NNP cord-001207-yjaiybwf 99 33 Louis Louis NNP cord-001207-yjaiybwf 99 34 , , , cord-001207-yjaiybwf 99 35 MO MO NNP cord-001207-yjaiybwf 99 36 , , , cord-001207-yjaiybwf 99 37 USA USA NNP cord-001207-yjaiybwf 99 38 ) ) -RRB- cord-001207-yjaiybwf 100 1 according accord VBG cord-001207-yjaiybwf 100 2 to to IN cord-001207-yjaiybwf 100 3 the the DT cord-001207-yjaiybwf 100 4 protocol protocol NN cord-001207-yjaiybwf 100 5 recommended recommend VBN cord-001207-yjaiybwf 100 6 by by IN cord-001207-yjaiybwf 100 7 the the DT cord-001207-yjaiybwf 100 8 supplier supplier NN cord-001207-yjaiybwf 100 9 ; ; : cord-001207-yjaiybwf 100 10 however however RB cord-001207-yjaiybwf 100 11 , , , cord-001207-yjaiybwf 100 12 the the DT cord-001207-yjaiybwf 100 13 annealing anneal VBG cord-001207-yjaiybwf 100 14 temperature temperature NN cord-001207-yjaiybwf 100 15 was be VBD cord-001207-yjaiybwf 100 16 decreased decrease VBN cord-001207-yjaiybwf 100 17 to to IN cord-001207-yjaiybwf 100 18 40uC 40uc CD cord-001207-yjaiybwf 100 19 ( ( -LRB- cord-001207-yjaiybwf 100 20 2 2 CD cord-001207-yjaiybwf 100 21 cycles cycle NNS cord-001207-yjaiybwf 100 22 ) ) -RRB- cord-001207-yjaiybwf 100 23 and and CC cord-001207-yjaiybwf 100 24 45uC 45uc CD cord-001207-yjaiybwf 100 25 ( ( -LRB- cord-001207-yjaiybwf 100 26 2 2 CD cord-001207-yjaiybwf 100 27 cycles cycle NNS cord-001207-yjaiybwf 100 28 ) ) -RRB- cord-001207-yjaiybwf 100 29 in in IN cord-001207-yjaiybwf 100 30 order order NN cord-001207-yjaiybwf 100 31 to to TO cord-001207-yjaiybwf 100 32 enable enable VB cord-001207-yjaiybwf 100 33 the the DT cord-001207-yjaiybwf 100 34 simultaneous simultaneous JJ cord-001207-yjaiybwf 100 35 amplification amplification NN cord-001207-yjaiybwf 100 36 of of IN cord-001207-yjaiybwf 100 37 DNA DNA NNP cord-001207-yjaiybwf 100 38 and and CC cord-001207-yjaiybwf 100 39 RNA RNA NNP cord-001207-yjaiybwf 100 40 [ [ -LRB- cord-001207-yjaiybwf 100 41 10 10 CD cord-001207-yjaiybwf 100 42 ] ] -RRB- cord-001207-yjaiybwf 100 43 . . . cord-001207-yjaiybwf 101 1 Aliquots Aliquots NNP cord-001207-yjaiybwf 101 2 of of IN cord-001207-yjaiybwf 101 3 75 75 CD cord-001207-yjaiybwf 101 4 ml ml NNS cord-001207-yjaiybwf 101 5 each each DT cord-001207-yjaiybwf 101 6 were be VBD cord-001207-yjaiybwf 101 7 removed remove VBN cord-001207-yjaiybwf 101 8 from from IN cord-001207-yjaiybwf 101 9 the the DT cord-001207-yjaiybwf 101 10 WTA2 WTA2 NNP cord-001207-yjaiybwf 101 11 reaction reaction NN cord-001207-yjaiybwf 101 12 at at IN cord-001207-yjaiybwf 101 13 different different JJ cord-001207-yjaiybwf 101 14 cycle cycle NN cord-001207-yjaiybwf 101 15 numbers number NNS cord-001207-yjaiybwf 101 16 , , , cord-001207-yjaiybwf 101 17 purified purify VBN cord-001207-yjaiybwf 101 18 and and CC cord-001207-yjaiybwf 101 19 size size NN cord-001207-yjaiybwf 101 20 - - HYPH cord-001207-yjaiybwf 101 21 selected select VBN cord-001207-yjaiybwf 101 22 using use VBG cord-001207-yjaiybwf 101 23 MobiSpin MobiSpin NNP cord-001207-yjaiybwf 101 24 S-400 S-400 NNP cord-001207-yjaiybwf 101 25 Columns Columns NNPS cord-001207-yjaiybwf 101 26 ( ( -LRB- cord-001207-yjaiybwf 101 27 MoBiTec MoBiTec NNP cord-001207-yjaiybwf 101 28 , , , cord-001207-yjaiybwf 101 29 Göttingen Göttingen NNP cord-001207-yjaiybwf 101 30 , , , cord-001207-yjaiybwf 101 31 Germany Germany NNP cord-001207-yjaiybwf 101 32 ) ) -RRB- cord-001207-yjaiybwf 101 33 . . . cord-001207-yjaiybwf 102 1 The the DT cord-001207-yjaiybwf 102 2 DNA dna NN cord-001207-yjaiybwf 102 3 concentration concentration NN cord-001207-yjaiybwf 102 4 was be VBD cord-001207-yjaiybwf 102 5 measured measure VBN cord-001207-yjaiybwf 102 6 from from IN cord-001207-yjaiybwf 102 7 the the DT cord-001207-yjaiybwf 102 8 preparations preparation NNS cord-001207-yjaiybwf 102 9 using use VBG cord-001207-yjaiybwf 102 10 a a DT cord-001207-yjaiybwf 102 11 nanodrop nanodrop NN cord-001207-yjaiybwf 102 12 spectrometer spectrometer NN cord-001207-yjaiybwf 102 13 ( ( -LRB- cord-001207-yjaiybwf 102 14 Analytic Analytic NNP cord-001207-yjaiybwf 102 15 Jena Jena NNP cord-001207-yjaiybwf 102 16 , , , cord-001207-yjaiybwf 102 17 Jena Jena NNP cord-001207-yjaiybwf 102 18 , , , cord-001207-yjaiybwf 102 19 Germany Germany NNP cord-001207-yjaiybwf 102 20 ) ) -RRB- cord-001207-yjaiybwf 102 21 and and CC cord-001207-yjaiybwf 102 22 the the DT cord-001207-yjaiybwf 102 23 preparation preparation NN cord-001207-yjaiybwf 102 24 derived derive VBN cord-001207-yjaiybwf 102 25 from from IN cord-001207-yjaiybwf 102 26 a a DT cord-001207-yjaiybwf 102 27 minimum minimum NN cord-001207-yjaiybwf 102 28 of of IN cord-001207-yjaiybwf 102 29 amplification amplification NN cord-001207-yjaiybwf 102 30 cycles cycle NNS cord-001207-yjaiybwf 102 31 with with IN cord-001207-yjaiybwf 102 32 a a DT cord-001207-yjaiybwf 102 33 DNA dna NN cord-001207-yjaiybwf 102 34 concentration concentration NN cord-001207-yjaiybwf 102 35 above above IN cord-001207-yjaiybwf 102 36 50 50 CD cord-001207-yjaiybwf 102 37 ng ng NNP cord-001207-yjaiybwf 102 38 / / SYM cord-001207-yjaiybwf 102 39 ml ml NN cord-001207-yjaiybwf 102 40 was be VBD cord-001207-yjaiybwf 102 41 chosen choose VBN cord-001207-yjaiybwf 102 42 for for IN cord-001207-yjaiybwf 102 43 deep deep JJ cord-001207-yjaiybwf 102 44 sequencing sequencing NN cord-001207-yjaiybwf 102 45 . . . cord-001207-yjaiybwf 103 1 A a DT cord-001207-yjaiybwf 103 2 total total NN cord-001207-yjaiybwf 103 3 of of IN cord-001207-yjaiybwf 103 4 1 1 CD cord-001207-yjaiybwf 103 5 mg mg NNP cord-001207-yjaiybwf 103 6 DNA DNA NNP cord-001207-yjaiybwf 103 7 was be VBD cord-001207-yjaiybwf 103 8 used use VBN cord-001207-yjaiybwf 103 9 for for IN cord-001207-yjaiybwf 103 10 deep deep JJ cord-001207-yjaiybwf 103 11 sequencing sequencing NN cord-001207-yjaiybwf 103 12 on on IN cord-001207-yjaiybwf 103 13 a a DT cord-001207-yjaiybwf 103 14 1/8 1/8 CD cord-001207-yjaiybwf 103 15 plate plate NN cord-001207-yjaiybwf 103 16 of of IN cord-001207-yjaiybwf 103 17 the the DT cord-001207-yjaiybwf 103 18 GS GS NNP cord-001207-yjaiybwf 103 19 - - HYPH cord-001207-yjaiybwf 103 20 FLX FLX NNP cord-001207-yjaiybwf 103 21 sequencer sequencer NN cord-001207-yjaiybwf 103 22 454 454 CD cord-001207-yjaiybwf 103 23 Titanium titanium NN cord-001207-yjaiybwf 103 24 ( ( -LRB- cord-001207-yjaiybwf 103 25 GS GS NNP cord-001207-yjaiybwf 103 26 Titanium Titanium NNP cord-001207-yjaiybwf 103 27 SV SV NNP cord-001207-yjaiybwf 103 28 emPCR empcr NN cord-001207-yjaiybwf 103 29 kit kit NN cord-001207-yjaiybwf 103 30 ( ( -LRB- cord-001207-yjaiybwf 103 31 Lib Lib NNP cord-001207-yjaiybwf 103 32 - - HYPH cord-001207-yjaiybwf 103 33 L L NNP cord-001207-yjaiybwf 103 34 ) ) -RRB- cord-001207-yjaiybwf 103 35 v2 v2 NN cord-001207-yjaiybwf 103 36 ; ; : cord-001207-yjaiybwf 103 37 GS GS NNP cord-001207-yjaiybwf 103 38 Titanium Titanium NNP cord-001207-yjaiybwf 103 39 PicoTiterPlate PicoTiterPlate NNP cord-001207-yjaiybwf 103 40 Kit kit NN cord-001207-yjaiybwf 103 41 70675 70675 CD cord-001207-yjaiybwf 103 42 ; ; : cord-001207-yjaiybwf 103 43 GS GS NNP cord-001207-yjaiybwf 103 44 Titanium Titanium NNP cord-001207-yjaiybwf 103 45 Sequencing Sequencing NNP cord-001207-yjaiybwf 103 46 Kit kit NN cord-001207-yjaiybwf 103 47 XLR70 xlr70 NN cord-001207-yjaiybwf 103 48 t t NN cord-001207-yjaiybwf 103 49 ; ; : cord-001207-yjaiybwf 103 50 Life Life NNP cord-001207-yjaiybwf 103 51 Sciences Sciences NNPS cord-001207-yjaiybwf 103 52 , , , cord-001207-yjaiybwf 103 53 Roche Roche NNP cord-001207-yjaiybwf 103 54 , , , cord-001207-yjaiybwf 103 55 Branford Branford NNP cord-001207-yjaiybwf 103 56 , , , cord-001207-yjaiybwf 103 57 USA USA NNP cord-001207-yjaiybwf 103 58 ) ) -RRB- cord-001207-yjaiybwf 104 1 according accord VBG cord-001207-yjaiybwf 104 2 to to IN cord-001207-yjaiybwf 104 3 the the DT cord-001207-yjaiybwf 104 4 manufacturer manufacturer NN cord-001207-yjaiybwf 104 5 's 's POS cord-001207-yjaiybwf 104 6 protocol protocol NN cord-001207-yjaiybwf 104 7 . . . cord-001207-yjaiybwf 105 1 The the DT cord-001207-yjaiybwf 105 2 raw raw JJ cord-001207-yjaiybwf 105 3 sequence sequence NN cord-001207-yjaiybwf 105 4 data datum NNS cord-001207-yjaiybwf 105 5 have have VBP cord-001207-yjaiybwf 105 6 been be VBN cord-001207-yjaiybwf 105 7 submitted submit VBN cord-001207-yjaiybwf 105 8 to to IN cord-001207-yjaiybwf 105 9 the the DT cord-001207-yjaiybwf 105 10 Sequence sequence NN cord-001207-yjaiybwf 105 11 Read Read NNP cord-001207-yjaiybwf 105 12 Archive Archive NNP cord-001207-yjaiybwf 105 13 ( ( -LRB- cord-001207-yjaiybwf 105 14 SRA SRA NNP cord-001207-yjaiybwf 105 15 ) ) -RRB- cord-001207-yjaiybwf 105 16 at at IN cord-001207-yjaiybwf 105 17 GenBank GenBank NNP cord-001207-yjaiybwf 105 18 as as IN cord-001207-yjaiybwf 105 19 BioProject BioProject NNP cord-001207-yjaiybwf 105 20 PRJNA232620 prjna232620 CD cord-001207-yjaiybwf 105 21 with with IN cord-001207-yjaiybwf 105 22 SRA SRA NNP cord-001207-yjaiybwf 105 23 accession accession NN cord-001207-yjaiybwf 105 24 numbers number NNS cord-001207-yjaiybwf 105 25 SRP034937 srp034937 NN cord-001207-yjaiybwf 105 26 ( ( -LRB- cord-001207-yjaiybwf 105 27 SRX396427-SRX396434 SRX396427-SRX396434 NNP cord-001207-yjaiybwf 105 28 ) ) -RRB- cord-001207-yjaiybwf 105 29 . . . cord-001207-yjaiybwf 106 1 Primary primary JJ cord-001207-yjaiybwf 106 2 sequence sequence NN cord-001207-yjaiybwf 106 3 analysis analysis NN cord-001207-yjaiybwf 106 4 was be VBD cord-001207-yjaiybwf 106 5 performed perform VBN cord-001207-yjaiybwf 106 6 in in IN cord-001207-yjaiybwf 106 7 two two CD cord-001207-yjaiybwf 106 8 steps step NNS cord-001207-yjaiybwf 106 9 : : : cord-001207-yjaiybwf 106 10 identification identification NN cord-001207-yjaiybwf 106 11 of of IN cord-001207-yjaiybwf 106 12 all all DT cord-001207-yjaiybwf 106 13 virus virus NN cord-001207-yjaiybwf 106 14 species specie NNS cord-001207-yjaiybwf 106 15 included include VBN cord-001207-yjaiybwf 106 16 in in IN cord-001207-yjaiybwf 106 17 the the DT cord-001207-yjaiybwf 106 18 samples sample NNS cord-001207-yjaiybwf 106 19 and and CC cord-001207-yjaiybwf 106 20 analysis analysis NN cord-001207-yjaiybwf 106 21 of of IN cord-001207-yjaiybwf 106 22 species specie NNS cord-001207-yjaiybwf 106 23 abundances abundance NNS cord-001207-yjaiybwf 106 24 regarding regard VBG cord-001207-yjaiybwf 106 25 selected select VBN cord-001207-yjaiybwf 106 26 sets set NNS cord-001207-yjaiybwf 106 27 of of IN cord-001207-yjaiybwf 106 28 species specie NNS cord-001207-yjaiybwf 106 29 . . . cord-001207-yjaiybwf 107 1 Raw raw JJ cord-001207-yjaiybwf 107 2 sequence sequence NN cord-001207-yjaiybwf 107 3 reads read VBZ cord-001207-yjaiybwf 107 4 were be VBD cord-001207-yjaiybwf 107 5 subjected subject VBN cord-001207-yjaiybwf 107 6 to to TO cord-001207-yjaiybwf 107 7 primer primer VB cord-001207-yjaiybwf 107 8 / / SYM cord-001207-yjaiybwf 107 9 adaptor adaptor NN cord-001207-yjaiybwf 107 10 trimming trimming NN cord-001207-yjaiybwf 107 11 using use VBG cord-001207-yjaiybwf 107 12 SeqMan SeqMan NNP cord-001207-yjaiybwf 107 13 ( ( -LRB- cord-001207-yjaiybwf 107 14 DNASTAR DNASTAR NNP cord-001207-yjaiybwf 107 15 , , , cord-001207-yjaiybwf 107 16 Lasergene Lasergene NNP cord-001207-yjaiybwf 107 17 , , , cord-001207-yjaiybwf 107 18 USA USA NNP cord-001207-yjaiybwf 107 19 ) ) -RRB- cord-001207-yjaiybwf 107 20 and and CC cord-001207-yjaiybwf 107 21 selection selection NN cord-001207-yjaiybwf 107 22 for for IN cord-001207-yjaiybwf 107 23 a a DT cord-001207-yjaiybwf 107 24 minimum minimum JJ cord-001207-yjaiybwf 107 25 length length NN cord-001207-yjaiybwf 107 26 of of IN cord-001207-yjaiybwf 107 27 50 50 CD cord-001207-yjaiybwf 107 28 nt nt RB cord-001207-yjaiybwf 107 29 . . . cord-001207-yjaiybwf 108 1 In in IN cord-001207-yjaiybwf 108 2 parallel parallel NN cord-001207-yjaiybwf 108 3 , , , cord-001207-yjaiybwf 108 4 all all DT cord-001207-yjaiybwf 108 5 primary primary JJ cord-001207-yjaiybwf 108 6 reads read NNS cord-001207-yjaiybwf 108 7 were be VBD cord-001207-yjaiybwf 108 8 subjected subject VBN cord-001207-yjaiybwf 108 9 to to IN cord-001207-yjaiybwf 108 10 de de NNP cord-001207-yjaiybwf 108 11 novo novo NNP cord-001207-yjaiybwf 108 12 contig contig NNP cord-001207-yjaiybwf 108 13 assemble assemble VBP cord-001207-yjaiybwf 108 14 using use VBG cord-001207-yjaiybwf 108 15 the the DT cord-001207-yjaiybwf 108 16 454 454 CD cord-001207-yjaiybwf 108 17 Newbler Newbler NNP cord-001207-yjaiybwf 108 18 Assembler Assembler NNP cord-001207-yjaiybwf 108 19 [ [ -LRB- cord-001207-yjaiybwf 108 20 40 40 CD cord-001207-yjaiybwf 108 21 ] ] -RRB- cord-001207-yjaiybwf 108 22 software software NN cord-001207-yjaiybwf 108 23 , , , cord-001207-yjaiybwf 108 24 with with IN cord-001207-yjaiybwf 108 25 criteria criterion NNS cord-001207-yjaiybwf 108 26 of of IN cord-001207-yjaiybwf 108 27 90 90 CD cord-001207-yjaiybwf 108 28 % % NN cord-001207-yjaiybwf 108 29 minimum minimum JJ cord-001207-yjaiybwf 108 30 overlap overlap NN cord-001207-yjaiybwf 108 31 identity identity NN cord-001207-yjaiybwf 108 32 and and CC cord-001207-yjaiybwf 108 33 a a DT cord-001207-yjaiybwf 108 34 minimum minimum JJ cord-001207-yjaiybwf 108 35 overlap overlap NN cord-001207-yjaiybwf 108 36 length length NN cord-001207-yjaiybwf 108 37 of of IN cord-001207-yjaiybwf 108 38 40 40 CD cord-001207-yjaiybwf 108 39 nt nt RB cord-001207-yjaiybwf 108 40 . . . cord-001207-yjaiybwf 109 1 In in IN cord-001207-yjaiybwf 109 2 order order NN cord-001207-yjaiybwf 109 3 to to TO cord-001207-yjaiybwf 109 4 create create VB cord-001207-yjaiybwf 109 5 a a DT cord-001207-yjaiybwf 109 6 local local JJ cord-001207-yjaiybwf 109 7 database database NN cord-001207-yjaiybwf 109 8 containing contain VBG cord-001207-yjaiybwf 109 9 all all DT cord-001207-yjaiybwf 109 10 virus virus NN cord-001207-yjaiybwf 109 11 sequences sequence NNS cord-001207-yjaiybwf 109 12 with with IN cord-001207-yjaiybwf 109 13 significant significant JJ cord-001207-yjaiybwf 109 14 homologies homology NNS cord-001207-yjaiybwf 109 15 to to IN cord-001207-yjaiybwf 109 16 the the DT cord-001207-yjaiybwf 109 17 sequence sequence NN cord-001207-yjaiybwf 109 18 reads read VBZ cord-001207-yjaiybwf 109 19 , , , cord-001207-yjaiybwf 109 20 homology homology NN cord-001207-yjaiybwf 109 21 searches search NNS cord-001207-yjaiybwf 109 22 for for IN cord-001207-yjaiybwf 109 23 all all DT cord-001207-yjaiybwf 109 24 primary primary JJ cord-001207-yjaiybwf 109 25 reads read NNS cord-001207-yjaiybwf 109 26 were be VBD cord-001207-yjaiybwf 109 27 performed perform VBN cord-001207-yjaiybwf 109 28 with with IN cord-001207-yjaiybwf 109 29 BLASTx BLASTx NNS cord-001207-yjaiybwf 109 30 [ [ -LRB- cord-001207-yjaiybwf 109 31 41 41 CD cord-001207-yjaiybwf 109 32 ] ] -RRB- cord-001207-yjaiybwf 109 33 against against IN cord-001207-yjaiybwf 109 34 the the DT cord-001207-yjaiybwf 109 35 non non JJ cord-001207-yjaiybwf 109 36 - - JJ cord-001207-yjaiybwf 109 37 redundant redundant JJ cord-001207-yjaiybwf 109 38 nucleotide nucleotide JJ cord-001207-yjaiybwf 109 39 database database NN cord-001207-yjaiybwf 109 40 of of IN cord-001207-yjaiybwf 109 41 NCBI NCBI NNP cord-001207-yjaiybwf 109 42 [ [ -LRB- cord-001207-yjaiybwf 109 43 42 42 CD cord-001207-yjaiybwf 109 44 ] ] -RRB- cord-001207-yjaiybwf 109 45 . . . cord-001207-yjaiybwf 110 1 In in IN cord-001207-yjaiybwf 110 2 parallel parallel NN cord-001207-yjaiybwf 110 3 , , , cord-001207-yjaiybwf 110 4 homology homology NN cord-001207-yjaiybwf 110 5 searches search NNS cord-001207-yjaiybwf 110 6 for for IN cord-001207-yjaiybwf 110 7 the the DT cord-001207-yjaiybwf 110 8 contigs contigs NNP cord-001207-yjaiybwf 110 9 were be VBD cord-001207-yjaiybwf 110 10 performed perform VBN cord-001207-yjaiybwf 110 11 with with IN cord-001207-yjaiybwf 110 12 CLC CLC NNP cord-001207-yjaiybwf 110 13 Main Main NNP cord-001207-yjaiybwf 110 14 Workbench Workbench NNP cord-001207-yjaiybwf 110 15 6.2 6.2 CD cord-001207-yjaiybwf 110 16 [ [ -LRB- cord-001207-yjaiybwf 110 17 43 43 CD cord-001207-yjaiybwf 110 18 ] ] -RRB- cord-001207-yjaiybwf 110 19 against against IN cord-001207-yjaiybwf 110 20 the the DT cord-001207-yjaiybwf 110 21 viral viral JJ cord-001207-yjaiybwf 110 22 genome genome NN cord-001207-yjaiybwf 110 23 nonredundant nonredundant JJ cord-001207-yjaiybwf 110 24 reference reference NN cord-001207-yjaiybwf 110 25 sequence sequence NN cord-001207-yjaiybwf 110 26 nucleotide nucleotide JJ cord-001207-yjaiybwf 110 27 database database NN cord-001207-yjaiybwf 110 28 [ [ -LRB- cord-001207-yjaiybwf 110 29 44 44 CD cord-001207-yjaiybwf 110 30 ] ] -RRB- cord-001207-yjaiybwf 110 31 and and CC cord-001207-yjaiybwf 110 32 additional additional JJ cord-001207-yjaiybwf 110 33 sequences sequence NNS cord-001207-yjaiybwf 110 34 from from IN cord-001207-yjaiybwf 110 35 recently recently RB cord-001207-yjaiybwf 110 36 discovered discover VBN cord-001207-yjaiybwf 110 37 viruses virus NNS cord-001207-yjaiybwf 110 38 using use VBG cord-001207-yjaiybwf 110 39 the the DT cord-001207-yjaiybwf 110 40 tBLASTx tblastx NN cord-001207-yjaiybwf 110 41 algorithms algorithm NNS cord-001207-yjaiybwf 110 42 [ [ -LRB- cord-001207-yjaiybwf 110 43 39 39 CD cord-001207-yjaiybwf 110 44 ] ] -RRB- cord-001207-yjaiybwf 110 45 . . . cord-001207-yjaiybwf 111 1 From from IN cord-001207-yjaiybwf 111 2 both both DT cord-001207-yjaiybwf 111 3 approaches approach NNS cord-001207-yjaiybwf 111 4 , , , cord-001207-yjaiybwf 111 5 all all DT cord-001207-yjaiybwf 111 6 BLAST blast NN cord-001207-yjaiybwf 111 7 results result VBZ cord-001207-yjaiybwf 111 8 with with IN cord-001207-yjaiybwf 111 9 an an DT cord-001207-yjaiybwf 111 10 E e NN cord-001207-yjaiybwf 111 11 - - NN cord-001207-yjaiybwf 111 12 value value NN cord-001207-yjaiybwf 111 13 , , , cord-001207-yjaiybwf 111 14 = = SYM cord-001207-yjaiybwf 111 15 10 10 CD cord-001207-yjaiybwf 111 16 24 24 CD cord-001207-yjaiybwf 111 17 were be VBD cord-001207-yjaiybwf 111 18 selected select VBN cord-001207-yjaiybwf 111 19 and and CC cord-001207-yjaiybwf 111 20 used use VBN cord-001207-yjaiybwf 111 21 for for IN cord-001207-yjaiybwf 111 22 creation creation NN cord-001207-yjaiybwf 111 23 of of IN cord-001207-yjaiybwf 111 24 the the DT cord-001207-yjaiybwf 111 25 local local JJ cord-001207-yjaiybwf 111 26 sequence sequence NN cord-001207-yjaiybwf 111 27 database database NN cord-001207-yjaiybwf 111 28 . . . cord-001207-yjaiybwf 112 1 Using use VBG cord-001207-yjaiybwf 112 2 this this DT cord-001207-yjaiybwf 112 3 database database NN cord-001207-yjaiybwf 112 4 , , , cord-001207-yjaiybwf 112 5 abundances abundance NNS cord-001207-yjaiybwf 112 6 of of IN cord-001207-yjaiybwf 112 7 species specie NNS cord-001207-yjaiybwf 112 8 were be VBD cord-001207-yjaiybwf 112 9 calculated calculate VBN cord-001207-yjaiybwf 112 10 . . . cord-001207-yjaiybwf 113 1 For for IN cord-001207-yjaiybwf 113 2 Bray Bray NNP cord-001207-yjaiybwf 113 3 Curtis Curtis NNP cord-001207-yjaiybwf 113 4 dissimilarity dissimilarity NN cord-001207-yjaiybwf 113 5 ( ( -LRB- cord-001207-yjaiybwf 113 6 see see VB cord-001207-yjaiybwf 113 7 below below RB cord-001207-yjaiybwf 113 8 ) ) -RRB- cord-001207-yjaiybwf 113 9 , , , cord-001207-yjaiybwf 113 10 specific specific JJ cord-001207-yjaiybwf 113 11 subsets subset NNS cord-001207-yjaiybwf 113 12 , , , cord-001207-yjaiybwf 113 13 which which WDT cord-001207-yjaiybwf 113 14 consisted consist VBD cord-001207-yjaiybwf 113 15 of of IN cord-001207-yjaiybwf 113 16 mammalian mammalian JJ cord-001207-yjaiybwf 113 17 viruses virus NNS cord-001207-yjaiybwf 113 18 , , , cord-001207-yjaiybwf 113 19 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 113 20 or or CC cord-001207-yjaiybwf 113 21 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 113 22 phages phage NNS cord-001207-yjaiybwf 113 23 , , , cord-001207-yjaiybwf 113 24 were be VBD cord-001207-yjaiybwf 113 25 used use VBN cord-001207-yjaiybwf 113 26 . . . cord-001207-yjaiybwf 114 1 In in IN cord-001207-yjaiybwf 114 2 all all DT cord-001207-yjaiybwf 114 3 cases case NNS cord-001207-yjaiybwf 114 4 , , , cord-001207-yjaiybwf 114 5 trimmed trim VBN cord-001207-yjaiybwf 114 6 reads read NNS cord-001207-yjaiybwf 114 7 were be VBD cord-001207-yjaiybwf 114 8 mapped map VBN cord-001207-yjaiybwf 114 9 against against IN cord-001207-yjaiybwf 114 10 the the DT cord-001207-yjaiybwf 114 11 sequences sequence NNS cord-001207-yjaiybwf 114 12 of of IN cord-001207-yjaiybwf 114 13 the the DT cord-001207-yjaiybwf 114 14 local local JJ cord-001207-yjaiybwf 114 15 database database NN cord-001207-yjaiybwf 114 16 to to TO cord-001207-yjaiybwf 114 17 calculate calculate VB cord-001207-yjaiybwf 114 18 species specie NNS cord-001207-yjaiybwf 114 19 abundances abundance NNS cord-001207-yjaiybwf 114 20 with with IN cord-001207-yjaiybwf 114 21 the the DT cord-001207-yjaiybwf 114 22 readmapper readmapper NN cord-001207-yjaiybwf 114 23 Bowtie Bowtie NNP cord-001207-yjaiybwf 114 24 2 2 CD cord-001207-yjaiybwf 114 25 2.0.5 2.0.5 CD cord-001207-yjaiybwf 114 26 [ [ -LRB- cord-001207-yjaiybwf 114 27 45 45 CD cord-001207-yjaiybwf 114 28 ] ] -RRB- cord-001207-yjaiybwf 114 29 . . . cord-001207-yjaiybwf 115 1 Thereafter thereafter RB cord-001207-yjaiybwf 115 2 , , , cord-001207-yjaiybwf 115 3 numbers number NNS cord-001207-yjaiybwf 115 4 of of IN cord-001207-yjaiybwf 115 5 mapped map VBN cord-001207-yjaiybwf 115 6 reads read NNS cord-001207-yjaiybwf 115 7 were be VBD cord-001207-yjaiybwf 115 8 corrected correct VBN cord-001207-yjaiybwf 115 9 for for IN cord-001207-yjaiybwf 115 10 multiple multiple JJ cord-001207-yjaiybwf 115 11 read read NN cord-001207-yjaiybwf 115 12 assignments assignment NNS cord-001207-yjaiybwf 115 13 . . . cord-001207-yjaiybwf 116 1 The the DT cord-001207-yjaiybwf 116 2 reads read NNS cord-001207-yjaiybwf 116 3 of of IN cord-001207-yjaiybwf 116 4 the the DT cord-001207-yjaiybwf 116 5 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 116 6 used use VBN cord-001207-yjaiybwf 116 7 as as IN cord-001207-yjaiybwf 116 8 process process NN cord-001207-yjaiybwf 116 9 control control NN cord-001207-yjaiybwf 116 10 were be VBD cord-001207-yjaiybwf 116 11 subtracted subtract VBN cord-001207-yjaiybwf 116 12 from from IN cord-001207-yjaiybwf 116 13 the the DT cord-001207-yjaiybwf 116 14 number number NN cord-001207-yjaiybwf 116 15 of of IN cord-001207-yjaiybwf 116 16 the the DT cord-001207-yjaiybwf 116 17 virus virus NN cord-001207-yjaiybwf 116 18 reads read VBZ cord-001207-yjaiybwf 116 19 in in IN cord-001207-yjaiybwf 116 20 subsequent subsequent JJ cord-001207-yjaiybwf 116 21 analyses analysis NNS cord-001207-yjaiybwf 116 22 . . . cord-001207-yjaiybwf 117 1 Shannon Shannon NNP cord-001207-yjaiybwf 117 2 index index NN cord-001207-yjaiybwf 117 3 [ [ -LRB- cord-001207-yjaiybwf 117 4 46 46 CD cord-001207-yjaiybwf 117 5 ] ] -RRB- cord-001207-yjaiybwf 117 6 was be VBD cord-001207-yjaiybwf 117 7 calculated calculate VBN cord-001207-yjaiybwf 117 8 to to TO cord-001207-yjaiybwf 117 9 compare compare VB cord-001207-yjaiybwf 117 10 the the DT cord-001207-yjaiybwf 117 11 diversity diversity NN cord-001207-yjaiybwf 117 12 of of IN cord-001207-yjaiybwf 117 13 the the DT cord-001207-yjaiybwf 117 14 species specie NNS cord-001207-yjaiybwf 117 15 identified identify VBN cord-001207-yjaiybwf 117 16 by by IN cord-001207-yjaiybwf 117 17 primary primary JJ cord-001207-yjaiybwf 117 18 reads read NNS cord-001207-yjaiybwf 117 19 . . . cord-001207-yjaiybwf 118 1 The the DT cord-001207-yjaiybwf 118 2 Shannon Shannon NNP cord-001207-yjaiybwf 118 3 index index NN cord-001207-yjaiybwf 118 4 is be VBZ cord-001207-yjaiybwf 118 5 maximal maximal JJ cord-001207-yjaiybwf 118 6 for for IN cord-001207-yjaiybwf 118 7 a a DT cord-001207-yjaiybwf 118 8 sample sample NN cord-001207-yjaiybwf 118 9 with with IN cord-001207-yjaiybwf 118 10 a a DT cord-001207-yjaiybwf 118 11 balanced balanced JJ cord-001207-yjaiybwf 118 12 species species NN cord-001207-yjaiybwf 118 13 distribution distribution NN cord-001207-yjaiybwf 118 14 and and CC cord-001207-yjaiybwf 118 15 it -PRON- PRP cord-001207-yjaiybwf 118 16 has have VBZ cord-001207-yjaiybwf 118 17 a a DT cord-001207-yjaiybwf 118 18 low low JJ cord-001207-yjaiybwf 118 19 value value NN cord-001207-yjaiybwf 118 20 for for IN cord-001207-yjaiybwf 118 21 a a DT cord-001207-yjaiybwf 118 22 sample sample NN cord-001207-yjaiybwf 118 23 with with IN cord-001207-yjaiybwf 118 24 an an DT cord-001207-yjaiybwf 118 25 uneven uneven JJ cord-001207-yjaiybwf 118 26 species species NN cord-001207-yjaiybwf 118 27 distribution distribution NN cord-001207-yjaiybwf 118 28 ; ; : cord-001207-yjaiybwf 118 29 e.g. e.g. RB cord-001207-yjaiybwf 118 30 if if IN cord-001207-yjaiybwf 118 31 some some DT cord-001207-yjaiybwf 118 32 single single JJ cord-001207-yjaiybwf 118 33 species specie NNS cord-001207-yjaiybwf 118 34 are be VBP cord-001207-yjaiybwf 118 35 a a DT cord-001207-yjaiybwf 118 36 highly highly RB cord-001207-yjaiybwf 118 37 abundant abundant JJ cord-001207-yjaiybwf 118 38 . . . cord-001207-yjaiybwf 119 1 The the DT cord-001207-yjaiybwf 119 2 maximal maximal JJ cord-001207-yjaiybwf 119 3 value value NN cord-001207-yjaiybwf 119 4 depends depend VBZ cord-001207-yjaiybwf 119 5 on on IN cord-001207-yjaiybwf 119 6 the the DT cord-001207-yjaiybwf 119 7 number number NN cord-001207-yjaiybwf 119 8 of of IN cord-001207-yjaiybwf 119 9 species specie NNS cord-001207-yjaiybwf 119 10 in in IN cord-001207-yjaiybwf 119 11 a a DT cord-001207-yjaiybwf 119 12 sample sample NN cord-001207-yjaiybwf 119 13 . . . cord-001207-yjaiybwf 120 1 Bray Bray NNP cord-001207-yjaiybwf 120 2 Curtis Curtis NNP cord-001207-yjaiybwf 120 3 dissimilarity dissimilarity NN cord-001207-yjaiybwf 120 4 [ [ -LRB- cord-001207-yjaiybwf 120 5 47 47 CD cord-001207-yjaiybwf 120 6 ] ] -RRB- cord-001207-yjaiybwf 120 7 was be VBD cord-001207-yjaiybwf 120 8 calculated calculate VBN cord-001207-yjaiybwf 120 9 for for IN cord-001207-yjaiybwf 120 10 pairwise pairwise JJ cord-001207-yjaiybwf 120 11 comparisons comparison NNS cord-001207-yjaiybwf 120 12 of of IN cord-001207-yjaiybwf 120 13 samples sample NNS cord-001207-yjaiybwf 120 14 and and CC cord-001207-yjaiybwf 120 15 dendrograms dendrogram NNS cord-001207-yjaiybwf 120 16 were be VBD cord-001207-yjaiybwf 120 17 constructed construct VBN cord-001207-yjaiybwf 120 18 by by IN cord-001207-yjaiybwf 120 19 hierarchical hierarchical JJ cord-001207-yjaiybwf 120 20 clustering clustering NN cord-001207-yjaiybwf 120 21 with with IN cord-001207-yjaiybwf 120 22 the the DT cord-001207-yjaiybwf 120 23 average average JJ cord-001207-yjaiybwf 120 24 linkage linkage NN cord-001207-yjaiybwf 120 25 method method NN cord-001207-yjaiybwf 120 26 . . . cord-001207-yjaiybwf 121 1 This this DT cord-001207-yjaiybwf 121 2 analysis analysis NN cord-001207-yjaiybwf 121 3 included include VBD cord-001207-yjaiybwf 121 4 counting counting NN cord-001207-yjaiybwf 121 5 of of IN cord-001207-yjaiybwf 121 6 detected detect VBN cord-001207-yjaiybwf 121 7 species specie NNS cord-001207-yjaiybwf 121 8 and and CC cord-001207-yjaiybwf 121 9 determination determination NN cord-001207-yjaiybwf 121 10 of of IN cord-001207-yjaiybwf 121 11 their -PRON- PRP$ cord-001207-yjaiybwf 121 12 taxonomy taxonomy NN cord-001207-yjaiybwf 121 13 , , , cord-001207-yjaiybwf 121 14 which which WDT cord-001207-yjaiybwf 121 15 was be VBD cord-001207-yjaiybwf 121 16 also also RB cord-001207-yjaiybwf 121 17 used use VBN cord-001207-yjaiybwf 121 18 to to TO cord-001207-yjaiybwf 121 19 determine determine VB cord-001207-yjaiybwf 121 20 the the DT cord-001207-yjaiybwf 121 21 virus virus NN cord-001207-yjaiybwf 121 22 hosts host NNS cord-001207-yjaiybwf 121 23 ( ( -LRB- cord-001207-yjaiybwf 121 24 bacteria bacteria NNS cord-001207-yjaiybwf 121 25 , , , cord-001207-yjaiybwf 121 26 vertebrates vertebrate NNS cord-001207-yjaiybwf 121 27 , , , cord-001207-yjaiybwf 121 28 plants plant NNS cord-001207-yjaiybwf 121 29 etc etc FW cord-001207-yjaiybwf 121 30 . . . cord-001207-yjaiybwf 121 31 ) ) -RRB- cord-001207-yjaiybwf 121 32 . . . cord-001207-yjaiybwf 122 1 A a DT cord-001207-yjaiybwf 122 2 total total NN cord-001207-yjaiybwf 122 3 of of IN cord-001207-yjaiybwf 122 4 8 8 CD cord-001207-yjaiybwf 122 5 pooled pooled JJ cord-001207-yjaiybwf 122 6 faecal faecal JJ cord-001207-yjaiybwf 122 7 samples sample NNS cord-001207-yjaiybwf 122 8 were be VBD cord-001207-yjaiybwf 122 9 derived derive VBN cord-001207-yjaiybwf 122 10 from from IN cord-001207-yjaiybwf 122 11 sows sow NNS cord-001207-yjaiybwf 122 12 and and CC cord-001207-yjaiybwf 122 13 their -PRON- PRP$ cord-001207-yjaiybwf 122 14 piglets piglet NNS cord-001207-yjaiybwf 122 15 from from IN cord-001207-yjaiybwf 122 16 an an DT cord-001207-yjaiybwf 122 17 experimental experimental JJ cord-001207-yjaiybwf 122 18 feeding feeding NN cord-001207-yjaiybwf 122 19 trial trial NN cord-001207-yjaiybwf 122 20 with with IN cord-001207-yjaiybwf 122 21 the the DT cord-001207-yjaiybwf 122 22 probiotic probiotic JJ cord-001207-yjaiybwf 122 23 bacterium bacterium NN cord-001207-yjaiybwf 122 24 E. E. NNP cord-001207-yjaiybwf 122 25 faecium faecium NN cord-001207-yjaiybwf 122 26 NCIMB NCIMB NNP cord-001207-yjaiybwf 122 27 10415 10415 CD cord-001207-yjaiybwf 122 28 . . . cord-001207-yjaiybwf 123 1 Four four CD cord-001207-yjaiybwf 123 2 of of IN cord-001207-yjaiybwf 123 3 the the DT cord-001207-yjaiybwf 123 4 samples sample NNS cord-001207-yjaiybwf 123 5 were be VBD cord-001207-yjaiybwf 123 6 derived derive VBN cord-001207-yjaiybwf 123 7 from from IN cord-001207-yjaiybwf 123 8 animals animal NNS cord-001207-yjaiybwf 123 9 receiving receive VBG cord-001207-yjaiybwf 123 10 the the DT cord-001207-yjaiybwf 123 11 probiotic probiotic JJ cord-001207-yjaiybwf 123 12 bacterium bacterium NN cord-001207-yjaiybwf 123 13 ( ( -LRB- cord-001207-yjaiybwf 123 14 group group NN cord-001207-yjaiybwf 123 15 P p NN cord-001207-yjaiybwf 123 16 ) ) -RRB- cord-001207-yjaiybwf 123 17 and and CC cord-001207-yjaiybwf 123 18 four four CD cord-001207-yjaiybwf 123 19 samples sample NNS cord-001207-yjaiybwf 123 20 originated originate VBD cord-001207-yjaiybwf 123 21 from from IN cord-001207-yjaiybwf 123 22 the the DT cord-001207-yjaiybwf 123 23 control control NN cord-001207-yjaiybwf 123 24 group group NN cord-001207-yjaiybwf 123 25 that that WDT cord-001207-yjaiybwf 123 26 did do VBD cord-001207-yjaiybwf 123 27 not not RB cord-001207-yjaiybwf 123 28 receive receive VB cord-001207-yjaiybwf 123 29 probiotics probiotic NNS cord-001207-yjaiybwf 123 30 ( ( -LRB- cord-001207-yjaiybwf 123 31 group group NN cord-001207-yjaiybwf 123 32 C C NNP cord-001207-yjaiybwf 123 33 ) ) -RRB- cord-001207-yjaiybwf 123 34 . . . cord-001207-yjaiybwf 124 1 A a DT cord-001207-yjaiybwf 124 2 detailed detailed JJ cord-001207-yjaiybwf 124 3 scheme scheme NN cord-001207-yjaiybwf 124 4 of of IN cord-001207-yjaiybwf 124 5 the the DT cord-001207-yjaiybwf 124 6 feeding feeding NN cord-001207-yjaiybwf 124 7 trial trial NN cord-001207-yjaiybwf 124 8 is be VBZ cord-001207-yjaiybwf 124 9 presented present VBN cord-001207-yjaiybwf 124 10 in in IN cord-001207-yjaiybwf 124 11 Figure figure NN cord-001207-yjaiybwf 124 12 1 1 CD cord-001207-yjaiybwf 124 13 . . . cord-001207-yjaiybwf 125 1 The the DT cord-001207-yjaiybwf 125 2 presence presence NN cord-001207-yjaiybwf 125 3 of of IN cord-001207-yjaiybwf 125 4 E. E. NNP cord-001207-yjaiybwf 125 5 faecium faecium NN cord-001207-yjaiybwf 125 6 NCIMB NCIMB NNP cord-001207-yjaiybwf 125 7 10415 10415 CD cord-001207-yjaiybwf 125 8 in in IN cord-001207-yjaiybwf 125 9 the the DT cord-001207-yjaiybwf 125 10 faeces faece NNS cord-001207-yjaiybwf 125 11 of of IN cord-001207-yjaiybwf 125 12 sows sow NNS cord-001207-yjaiybwf 125 13 and and CC cord-001207-yjaiybwf 125 14 their -PRON- PRP$ cord-001207-yjaiybwf 125 15 piglets piglet NNS cord-001207-yjaiybwf 125 16 was be VBD cord-001207-yjaiybwf 125 17 analyzed analyze VBN cord-001207-yjaiybwf 125 18 by by IN cord-001207-yjaiybwf 125 19 quantitative quantitative JJ cord-001207-yjaiybwf 125 20 real real JJ cord-001207-yjaiybwf 125 21 - - HYPH cord-001207-yjaiybwf 125 22 time time NN cord-001207-yjaiybwf 125 23 PCR PCR NNP cord-001207-yjaiybwf 125 24 . . . cord-001207-yjaiybwf 126 1 As as IN cord-001207-yjaiybwf 126 2 shown show VBN cord-001207-yjaiybwf 126 3 in in IN cord-001207-yjaiybwf 126 4 Table Table NNP cord-001207-yjaiybwf 126 5 1 1 CD cord-001207-yjaiybwf 126 6 , , , cord-001207-yjaiybwf 126 7 E. E. NNP cord-001207-yjaiybwf 126 8 faecium faecium NNP cord-001207-yjaiybwf 127 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 127 2 10415 10415 CD cord-001207-yjaiybwf 127 3 was be VBD cord-001207-yjaiybwf 127 4 not not RB cord-001207-yjaiybwf 127 5 detected detect VBN cord-001207-yjaiybwf 127 6 in in IN cord-001207-yjaiybwf 127 7 the the DT cord-001207-yjaiybwf 127 8 samples sample NNS cord-001207-yjaiybwf 127 9 of of IN cord-001207-yjaiybwf 127 10 the the DT cord-001207-yjaiybwf 127 11 control control NN cord-001207-yjaiybwf 127 12 group group NN cord-001207-yjaiybwf 127 13 . . . cord-001207-yjaiybwf 128 1 Also also RB cord-001207-yjaiybwf 128 2 , , , cord-001207-yjaiybwf 128 3 no no DT cord-001207-yjaiybwf 128 4 E. E. NNP cord-001207-yjaiybwf 128 5 faecium faecium NN cord-001207-yjaiybwf 128 6 NCIMB NCIMB NNP cord-001207-yjaiybwf 128 7 was be VBD cord-001207-yjaiybwf 128 8 detectable detectable JJ cord-001207-yjaiybwf 128 9 in in IN cord-001207-yjaiybwf 128 10 the the DT cord-001207-yjaiybwf 128 11 sample sample NN cord-001207-yjaiybwf 128 12 taken take VBN cord-001207-yjaiybwf 128 13 from from IN cord-001207-yjaiybwf 128 14 the the DT cord-001207-yjaiybwf 128 15 sows sow NNS cord-001207-yjaiybwf 128 16 of of IN cord-001207-yjaiybwf 128 17 the the DT cord-001207-yjaiybwf 128 18 probiotic probiotic JJ cord-001207-yjaiybwf 128 19 group group NN cord-001207-yjaiybwf 128 20 immediately immediately RB cord-001207-yjaiybwf 128 21 at at IN cord-001207-yjaiybwf 128 22 the the DT cord-001207-yjaiybwf 128 23 beginning beginning NN cord-001207-yjaiybwf 128 24 of of IN cord-001207-yjaiybwf 128 25 the the DT cord-001207-yjaiybwf 128 26 experiment experiment NN cord-001207-yjaiybwf 128 27 ( ( -LRB- cord-001207-yjaiybwf 128 28 28 28 CD cord-001207-yjaiybwf 128 29 day day NN cord-001207-yjaiybwf 128 30 ante ante NNP cord-001207-yjaiybwf 128 31 partum partum NNP cord-001207-yjaiybwf 128 32 ) ) -RRB- cord-001207-yjaiybwf 128 33 as as RB cord-001207-yjaiybwf 128 34 well well RB cord-001207-yjaiybwf 128 35 as as IN cord-001207-yjaiybwf 128 36 in in IN cord-001207-yjaiybwf 128 37 the the DT cord-001207-yjaiybwf 128 38 samples sample NNS cord-001207-yjaiybwf 128 39 from from IN cord-001207-yjaiybwf 128 40 the the DT cord-001207-yjaiybwf 128 41 12 12 CD cord-001207-yjaiybwf 128 42 day day NN cord-001207-yjaiybwf 128 43 - - HYPH cord-001207-yjaiybwf 128 44 old old JJ cord-001207-yjaiybwf 128 45 piglets piglet NNS cord-001207-yjaiybwf 128 46 of of IN cord-001207-yjaiybwf 128 47 this this DT cord-001207-yjaiybwf 128 48 group group NN cord-001207-yjaiybwf 128 49 , , , cord-001207-yjaiybwf 128 50 which which WDT cord-001207-yjaiybwf 128 51 were be VBD cord-001207-yjaiybwf 128 52 still still RB cord-001207-yjaiybwf 128 53 suckled suckle VBN cord-001207-yjaiybwf 128 54 at at IN cord-001207-yjaiybwf 128 55 this this DT cord-001207-yjaiybwf 128 56 time time NN cord-001207-yjaiybwf 128 57 - - HYPH cord-001207-yjaiybwf 128 58 point point NN cord-001207-yjaiybwf 128 59 . . . cord-001207-yjaiybwf 129 1 Considerable considerable JJ cord-001207-yjaiybwf 129 2 amounts amount NNS cord-001207-yjaiybwf 129 3 of of IN cord-001207-yjaiybwf 129 4 E. E. NNP cord-001207-yjaiybwf 129 5 faecium faecium NN cord-001207-yjaiybwf 129 6 NCIMB NCIMB NNP cord-001207-yjaiybwf 129 7 10415 10415 CD cord-001207-yjaiybwf 129 8 were be VBD cord-001207-yjaiybwf 129 9 demonstrated demonstrate VBN cord-001207-yjaiybwf 129 10 in in IN cord-001207-yjaiybwf 129 11 the the DT cord-001207-yjaiybwf 129 12 samples sample NNS cord-001207-yjaiybwf 129 13 taken take VBN cord-001207-yjaiybwf 129 14 from from IN cord-001207-yjaiybwf 129 15 the the DT cord-001207-yjaiybwf 129 16 sows sow NNS cord-001207-yjaiybwf 129 17 at at IN cord-001207-yjaiybwf 129 18 14 14 CD cord-001207-yjaiybwf 129 19 day day NN cord-001207-yjaiybwf 129 20 post post NN cord-001207-yjaiybwf 129 21 partum partum NN cord-001207-yjaiybwf 129 22 and and CC cord-001207-yjaiybwf 129 23 from from IN cord-001207-yjaiybwf 129 24 the the DT cord-001207-yjaiybwf 129 25 54 54 CD cord-001207-yjaiybwf 129 26 day day NN cord-001207-yjaiybwf 129 27 - - HYPH cord-001207-yjaiybwf 129 28 old old JJ cord-001207-yjaiybwf 129 29 piglets piglet NNS cord-001207-yjaiybwf 129 30 , , , cord-001207-yjaiybwf 129 31 both both DT cord-001207-yjaiybwf 129 32 belonging belong VBG cord-001207-yjaiybwf 129 33 to to IN cord-001207-yjaiybwf 129 34 the the DT cord-001207-yjaiybwf 129 35 probiotic probiotic JJ cord-001207-yjaiybwf 129 36 group group NN cord-001207-yjaiybwf 129 37 . . . cord-001207-yjaiybwf 130 1 The the DT cord-001207-yjaiybwf 130 2 8 8 CD cord-001207-yjaiybwf 130 3 pooled pool VBN cord-001207-yjaiybwf 130 4 faecal faecal JJ cord-001207-yjaiybwf 130 5 samples sample NNS cord-001207-yjaiybwf 130 6 were be VBD cord-001207-yjaiybwf 130 7 analyzed analyze VBN cord-001207-yjaiybwf 130 8 by by IN cord-001207-yjaiybwf 130 9 processcontrolled processcontrolle VBN cord-001207-yjaiybwf 130 10 deep deep JJ cord-001207-yjaiybwf 130 11 sequencing sequencing NN cord-001207-yjaiybwf 130 12 . . . cord-001207-yjaiybwf 131 1 In in IN cord-001207-yjaiybwf 131 2 total total NN cord-001207-yjaiybwf 131 3 , , , cord-001207-yjaiybwf 131 4 390,650 390,650 CD cord-001207-yjaiybwf 131 5 reads read NNS cord-001207-yjaiybwf 131 6 were be VBD cord-001207-yjaiybwf 131 7 generated generate VBN cord-001207-yjaiybwf 131 8 , , , cord-001207-yjaiybwf 131 9 with with IN cord-001207-yjaiybwf 131 10 an an DT cord-001207-yjaiybwf 131 11 average average NN cord-001207-yjaiybwf 131 12 of of IN cord-001207-yjaiybwf 131 13 48,831 48,831 CD cord-001207-yjaiybwf 131 14 reads read NNS cord-001207-yjaiybwf 131 15 per per IN cord-001207-yjaiybwf 131 16 sample sample NN cord-001207-yjaiybwf 131 17 . . . cord-001207-yjaiybwf 132 1 The the DT cord-001207-yjaiybwf 132 2 efficiency efficiency NN cord-001207-yjaiybwf 132 3 of of IN cord-001207-yjaiybwf 132 4 the the DT cord-001207-yjaiybwf 132 5 whole whole JJ cord-001207-yjaiybwf 132 6 method method NN cord-001207-yjaiybwf 132 7 was be VBD cord-001207-yjaiybwf 132 8 monitored monitor VBN cord-001207-yjaiybwf 132 9 by by IN cord-001207-yjaiybwf 132 10 a a DT cord-001207-yjaiybwf 132 11 process process NN cord-001207-yjaiybwf 132 12 control control NN cord-001207-yjaiybwf 132 13 consisting consist VBG cord-001207-yjaiybwf 132 14 of of IN cord-001207-yjaiybwf 132 15 three three CD cord-001207-yjaiybwf 132 16 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 132 17 , , , cord-001207-yjaiybwf 132 18 which which WDT cord-001207-yjaiybwf 132 19 were be VBD cord-001207-yjaiybwf 132 20 added add VBN cord-001207-yjaiybwf 132 21 in in IN cord-001207-yjaiybwf 132 22 constant constant JJ cord-001207-yjaiybwf 132 23 amounts amount NNS cord-001207-yjaiybwf 132 24 to to IN cord-001207-yjaiybwf 132 25 the the DT cord-001207-yjaiybwf 132 26 samples sample NNS cord-001207-yjaiybwf 132 27 . . . cord-001207-yjaiybwf 133 1 In in IN cord-001207-yjaiybwf 133 2 all all DT cord-001207-yjaiybwf 133 3 samples sample NNS cord-001207-yjaiybwf 133 4 the the DT cord-001207-yjaiybwf 133 5 three three CD cord-001207-yjaiybwf 133 6 test test NN cord-001207-yjaiybwf 133 7 - - HYPH cord-001207-yjaiybwf 133 8 phages phage NNS cord-001207-yjaiybwf 133 9 could could MD cord-001207-yjaiybwf 133 10 be be VB cord-001207-yjaiybwf 133 11 detected detect VBN cord-001207-yjaiybwf 133 12 representing represent VBG cord-001207-yjaiybwf 133 13 0.9 0.9 CD cord-001207-yjaiybwf 133 14 % % NN cord-001207-yjaiybwf 133 15 to to IN cord-001207-yjaiybwf 133 16 3.4 3.4 CD cord-001207-yjaiybwf 133 17 % % NN cord-001207-yjaiybwf 133 18 of of IN cord-001207-yjaiybwf 133 19 all all DT cord-001207-yjaiybwf 133 20 generated generate VBN cord-001207-yjaiybwf 133 21 reads read NNS cord-001207-yjaiybwf 133 22 . . . cord-001207-yjaiybwf 134 1 The the DT cord-001207-yjaiybwf 134 2 numbers number NNS cord-001207-yjaiybwf 134 3 of of IN cord-001207-yjaiybwf 134 4 totally totally RB cord-001207-yjaiybwf 134 5 generated generate VBN cord-001207-yjaiybwf 134 6 reads read NNS cord-001207-yjaiybwf 134 7 , , , cord-001207-yjaiybwf 134 8 test test NN cord-001207-yjaiybwf 134 9 - - HYPH cord-001207-yjaiybwf 134 10 phage phage NN cord-001207-yjaiybwf 134 11 reads read NNS cord-001207-yjaiybwf 134 12 and and CC cord-001207-yjaiybwf 134 13 other other JJ cord-001207-yjaiybwf 134 14 virus virus NN cord-001207-yjaiybwf 134 15 reads read VBZ cord-001207-yjaiybwf 134 16 is be VBZ cord-001207-yjaiybwf 134 17 summarized summarize VBN cord-001207-yjaiybwf 134 18 for for IN cord-001207-yjaiybwf 134 19 the the DT cord-001207-yjaiybwf 134 20 individual individual JJ cord-001207-yjaiybwf 134 21 samples sample NNS cord-001207-yjaiybwf 134 22 in in IN cord-001207-yjaiybwf 134 23 Table Table NNP cord-001207-yjaiybwf 134 24 2 2 CD cord-001207-yjaiybwf 134 25 . . . cord-001207-yjaiybwf 135 1 The the DT cord-001207-yjaiybwf 135 2 number number NN cord-001207-yjaiybwf 135 3 of of IN cord-001207-yjaiybwf 135 4 the the DT cord-001207-yjaiybwf 135 5 test test NN cord-001207-yjaiybwf 135 6 - - HYPH cord-001207-yjaiybwf 135 7 phage phage NN cord-001207-yjaiybwf 135 8 reads read NNS cord-001207-yjaiybwf 135 9 in in IN cord-001207-yjaiybwf 135 10 relation relation NN cord-001207-yjaiybwf 135 11 to to IN cord-001207-yjaiybwf 135 12 the the DT cord-001207-yjaiybwf 135 13 total total JJ cord-001207-yjaiybwf 135 14 virus virus NN cord-001207-yjaiybwf 135 15 reads read VBZ cord-001207-yjaiybwf 135 16 ranged range VBD cord-001207-yjaiybwf 135 17 from from IN cord-001207-yjaiybwf 135 18 3.8 3.8 CD cord-001207-yjaiybwf 135 19 % % NN cord-001207-yjaiybwf 135 20 to to IN cord-001207-yjaiybwf 135 21 24.4 24.4 CD cord-001207-yjaiybwf 135 22 % % NN cord-001207-yjaiybwf 135 23 and and CC cord-001207-yjaiybwf 135 24 is be VBZ cord-001207-yjaiybwf 135 25 shown show VBN cord-001207-yjaiybwf 135 26 in in IN cord-001207-yjaiybwf 135 27 Figure figure NN cord-001207-yjaiybwf 135 28 2 2 CD cord-001207-yjaiybwf 135 29 . . . cord-001207-yjaiybwf 136 1 Using use VBG cord-001207-yjaiybwf 136 2 a a DT cord-001207-yjaiybwf 136 3 cut cut VB cord-001207-yjaiybwf 136 4 - - HYPH cord-001207-yjaiybwf 136 5 off off RP cord-001207-yjaiybwf 136 6 E e NN cord-001207-yjaiybwf 136 7 - - NN cord-001207-yjaiybwf 136 8 value value NN cord-001207-yjaiybwf 136 9 of of IN cord-001207-yjaiybwf 136 10 , , , cord-001207-yjaiybwf 136 11 = = SYM cord-001207-yjaiybwf 136 12 10 10 CD cord-001207-yjaiybwf 136 13 24 24 CD cord-001207-yjaiybwf 136 14 for for IN cord-001207-yjaiybwf 136 15 the the DT cord-001207-yjaiybwf 136 16 BLASTx BLASTx NNS cord-001207-yjaiybwf 136 17 homology homology NN cord-001207-yjaiybwf 136 18 search search NN cord-001207-yjaiybwf 136 19 of of IN cord-001207-yjaiybwf 136 20 the the DT cord-001207-yjaiybwf 136 21 sequences sequence NNS cord-001207-yjaiybwf 136 22 , , , cord-001207-yjaiybwf 136 23 the the DT cord-001207-yjaiybwf 136 24 viral viral JJ cord-001207-yjaiybwf 136 25 reads read NNS cord-001207-yjaiybwf 136 26 could could MD cord-001207-yjaiybwf 136 27 be be VB cord-001207-yjaiybwf 136 28 assigned assign VBN cord-001207-yjaiybwf 136 29 to to IN cord-001207-yjaiybwf 136 30 36 36 CD cord-001207-yjaiybwf 136 31 known know VBN cord-001207-yjaiybwf 136 32 virus virus NN cord-001207-yjaiybwf 136 33 families family NNS cord-001207-yjaiybwf 136 34 . . . cord-001207-yjaiybwf 137 1 Only only RB cord-001207-yjaiybwf 137 2 10 10 CD cord-001207-yjaiybwf 137 3 of of IN cord-001207-yjaiybwf 137 4 these these DT cord-001207-yjaiybwf 137 5 families family NNS cord-001207-yjaiybwf 137 6 dominated dominate VBD cord-001207-yjaiybwf 137 7 the the DT cord-001207-yjaiybwf 137 8 faecal faecal JJ cord-001207-yjaiybwf 137 9 viromes virome NNS cord-001207-yjaiybwf 137 10 representing represent VBG cord-001207-yjaiybwf 137 11 more more JJR cord-001207-yjaiybwf 137 12 than than IN cord-001207-yjaiybwf 137 13 1 1 CD cord-001207-yjaiybwf 137 14 % % NN cord-001207-yjaiybwf 137 15 in in IN cord-001207-yjaiybwf 137 16 at at RB cord-001207-yjaiybwf 137 17 least least RBS cord-001207-yjaiybwf 137 18 one one CD cord-001207-yjaiybwf 137 19 of of IN cord-001207-yjaiybwf 137 20 the the DT cord-001207-yjaiybwf 137 21 samples sample NNS cord-001207-yjaiybwf 137 22 . . . cord-001207-yjaiybwf 138 1 As as IN cord-001207-yjaiybwf 138 2 shown show VBN cord-001207-yjaiybwf 138 3 in in IN cord-001207-yjaiybwf 138 4 Figure Figure NNP cord-001207-yjaiybwf 138 5 3 3 CD cord-001207-yjaiybwf 138 6 and and CC cord-001207-yjaiybwf 138 7 Table Table NNP cord-001207-yjaiybwf 138 8 S1 S1 NNP cord-001207-yjaiybwf 138 9 , , , cord-001207-yjaiybwf 138 10 the the DT cord-001207-yjaiybwf 138 11 composition composition NN cord-001207-yjaiybwf 138 12 of of IN cord-001207-yjaiybwf 138 13 the the DT cord-001207-yjaiybwf 138 14 faecal faecal JJ cord-001207-yjaiybwf 138 15 viromes virome NNS cord-001207-yjaiybwf 138 16 according accord VBG cord-001207-yjaiybwf 138 17 to to IN cord-001207-yjaiybwf 138 18 virus virus NN cord-001207-yjaiybwf 138 19 families family NNS cord-001207-yjaiybwf 138 20 varied vary VBN cord-001207-yjaiybwf 138 21 remarkably remarkably RB cord-001207-yjaiybwf 138 22 among among IN cord-001207-yjaiybwf 138 23 the the DT cord-001207-yjaiybwf 138 24 samples sample NNS cord-001207-yjaiybwf 138 25 . . . cord-001207-yjaiybwf 139 1 A a DT cord-001207-yjaiybwf 139 2 grouping grouping NN cord-001207-yjaiybwf 139 3 of of IN cord-001207-yjaiybwf 139 4 the the DT cord-001207-yjaiybwf 139 5 virus virus NN cord-001207-yjaiybwf 139 6 families family NNS cord-001207-yjaiybwf 139 7 according accord VBG cord-001207-yjaiybwf 139 8 to to IN cord-001207-yjaiybwf 139 9 the the DT cord-001207-yjaiybwf 139 10 taxonomic taxonomic JJ cord-001207-yjaiybwf 139 11 kingdom kingdom NN cord-001207-yjaiybwf 139 12 of of IN cord-001207-yjaiybwf 139 13 hosts host NNS cord-001207-yjaiybwf 139 14 of of IN cord-001207-yjaiybwf 139 15 the the DT cord-001207-yjaiybwf 139 16 contained contain VBN cord-001207-yjaiybwf 139 17 viruses virus NNS cord-001207-yjaiybwf 139 18 revealed reveal VBD cord-001207-yjaiybwf 139 19 that that IN cord-001207-yjaiybwf 139 20 the the DT cord-001207-yjaiybwf 139 21 main main JJ cord-001207-yjaiybwf 139 22 detected detected JJ cord-001207-yjaiybwf 139 23 groups group NNS cord-001207-yjaiybwf 139 24 were be VBD cord-001207-yjaiybwf 139 25 mammalian mammalian JJ cord-001207-yjaiybwf 139 26 viruses virus NNS cord-001207-yjaiybwf 139 27 ( ( -LRB- cord-001207-yjaiybwf 139 28 colored color VBN cord-001207-yjaiybwf 139 29 red red NN cord-001207-yjaiybwf 139 30 in in IN cord-001207-yjaiybwf 139 31 Fig Fig NNP cord-001207-yjaiybwf 139 32 . . . cord-001207-yjaiybwf 139 33 3 3 CD cord-001207-yjaiybwf 139 34 ) ) -RRB- cord-001207-yjaiybwf 139 35 and and CC cord-001207-yjaiybwf 139 36 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 139 37 ( ( -LRB- cord-001207-yjaiybwf 139 38 colored color VBN cord-001207-yjaiybwf 139 39 blue blue NN cord-001207-yjaiybwf 139 40 in in IN cord-001207-yjaiybwf 139 41 Fig Fig NNP cord-001207-yjaiybwf 139 42 . . . cord-001207-yjaiybwf 139 43 3 3 CD cord-001207-yjaiybwf 139 44 ) ) -RRB- cord-001207-yjaiybwf 139 45 . . . cord-001207-yjaiybwf 140 1 In in IN cord-001207-yjaiybwf 140 2 contrast contrast NN cord-001207-yjaiybwf 140 3 , , , cord-001207-yjaiybwf 140 4 viruses virus NNS cord-001207-yjaiybwf 140 5 from from IN cord-001207-yjaiybwf 140 6 other other JJ cord-001207-yjaiybwf 140 7 hosts host NNS cord-001207-yjaiybwf 140 8 ( ( -LRB- cord-001207-yjaiybwf 140 9 insects insect NNS cord-001207-yjaiybwf 140 10 , , , cord-001207-yjaiybwf 140 11 plants plant NNS cord-001207-yjaiybwf 140 12 , , , cord-001207-yjaiybwf 140 13 amphibians amphibian NNS cord-001207-yjaiybwf 140 14 and and CC cord-001207-yjaiybwf 140 15 fungi fungus NNS cord-001207-yjaiybwf 140 16 ) ) -RRB- cord-001207-yjaiybwf 140 17 ranked rank VBD cord-001207-yjaiybwf 140 18 together together RB cord-001207-yjaiybwf 140 19 between between IN cord-001207-yjaiybwf 140 20 0.2 0.2 CD cord-001207-yjaiybwf 140 21 % % NN cord-001207-yjaiybwf 140 22 and and CC cord-001207-yjaiybwf 140 23 3.4 3.4 CD cord-001207-yjaiybwf 140 24 % % NN cord-001207-yjaiybwf 140 25 only only RB cord-001207-yjaiybwf 140 26 . . . cord-001207-yjaiybwf 141 1 A a DT cord-001207-yjaiybwf 141 2 closer close JJR cord-001207-yjaiybwf 141 3 inspection inspection NN cord-001207-yjaiybwf 141 4 of of IN cord-001207-yjaiybwf 141 5 the the DT cord-001207-yjaiybwf 141 6 proportion proportion NN cord-001207-yjaiybwf 141 7 of of IN cord-001207-yjaiybwf 141 8 the the DT cord-001207-yjaiybwf 141 9 read read VBN cord-001207-yjaiybwf 141 10 numbers number NNS cord-001207-yjaiybwf 141 11 from from IN cord-001207-yjaiybwf 141 12 mammalian mammalian JJ cord-001207-yjaiybwf 141 13 viruses virus NNS cord-001207-yjaiybwf 141 14 compared compare VBN cord-001207-yjaiybwf 141 15 to to IN cord-001207-yjaiybwf 141 16 that that DT cord-001207-yjaiybwf 141 17 from from IN cord-001207-yjaiybwf 141 18 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 141 19 revealed reveal VBD cord-001207-yjaiybwf 141 20 marked marked JJ cord-001207-yjaiybwf 141 21 differences difference NNS cord-001207-yjaiybwf 141 22 between between IN cord-001207-yjaiybwf 141 23 the the DT cord-001207-yjaiybwf 141 24 samples sample NNS cord-001207-yjaiybwf 141 25 derived derive VBN cord-001207-yjaiybwf 141 26 from from IN cord-001207-yjaiybwf 141 27 different different JJ cord-001207-yjaiybwf 141 28 age age NN cord-001207-yjaiybwf 141 29 groups group NNS cord-001207-yjaiybwf 141 30 . . . cord-001207-yjaiybwf 142 1 In in IN cord-001207-yjaiybwf 142 2 the the DT cord-001207-yjaiybwf 142 3 youngest young JJS cord-001207-yjaiybwf 142 4 piglet piglet NN cord-001207-yjaiybwf 142 5 group group NN cord-001207-yjaiybwf 142 6 ( ( -LRB- cord-001207-yjaiybwf 142 7 12 12 CD cord-001207-yjaiybwf 142 8 days day NNS cord-001207-yjaiybwf 142 9 of of IN cord-001207-yjaiybwf 142 10 age age NN cord-001207-yjaiybwf 142 11 ) ) -RRB- cord-001207-yjaiybwf 142 12 , , , cord-001207-yjaiybwf 142 13 the the DT cord-001207-yjaiybwf 142 14 main main JJ cord-001207-yjaiybwf 142 15 fraction fraction NN cord-001207-yjaiybwf 142 16 consisted consist VBD cord-001207-yjaiybwf 142 17 of of IN cord-001207-yjaiybwf 142 18 mammalian mammalian JJ cord-001207-yjaiybwf 142 19 viruses virus NNS cord-001207-yjaiybwf 142 20 with with IN cord-001207-yjaiybwf 142 21 55 55 CD cord-001207-yjaiybwf 142 22 % % NN cord-001207-yjaiybwf 142 23 ( ( -LRB- cord-001207-yjaiybwf 142 24 control control NN cord-001207-yjaiybwf 142 25 group group NN cord-001207-yjaiybwf 142 26 ) ) -RRB- cord-001207-yjaiybwf 142 27 and and CC cord-001207-yjaiybwf 142 28 77 77 CD cord-001207-yjaiybwf 142 29 % % NN cord-001207-yjaiybwf 142 30 ( ( -LRB- cord-001207-yjaiybwf 142 31 probiotic probiotic JJ cord-001207-yjaiybwf 142 32 group group NN cord-001207-yjaiybwf 142 33 ) ) -RRB- cord-001207-yjaiybwf 142 34 . . . cord-001207-yjaiybwf 143 1 In in IN cord-001207-yjaiybwf 143 2 the the DT cord-001207-yjaiybwf 143 3 group group NN cord-001207-yjaiybwf 143 4 of of IN cord-001207-yjaiybwf 143 5 54 54 CD cord-001207-yjaiybwf 143 6 dayold dayold NN cord-001207-yjaiybwf 143 7 piglets piglet NNS cord-001207-yjaiybwf 143 8 , , , cord-001207-yjaiybwf 143 9 the the DT cord-001207-yjaiybwf 143 10 proportion proportion NN cord-001207-yjaiybwf 143 11 of of IN cord-001207-yjaiybwf 143 12 mammalian mammalian JJ cord-001207-yjaiybwf 143 13 viruses virus NNS cord-001207-yjaiybwf 143 14 was be VBD cord-001207-yjaiybwf 143 15 reduced reduce VBN cord-001207-yjaiybwf 143 16 to to IN cord-001207-yjaiybwf 143 17 24 24 CD cord-001207-yjaiybwf 143 18 % % NN cord-001207-yjaiybwf 143 19 ( ( -LRB- cord-001207-yjaiybwf 143 20 control control NN cord-001207-yjaiybwf 143 21 group group NN cord-001207-yjaiybwf 143 22 ) ) -RRB- cord-001207-yjaiybwf 143 23 and and CC cord-001207-yjaiybwf 143 24 30 30 CD cord-001207-yjaiybwf 143 25 % % NN cord-001207-yjaiybwf 143 26 ( ( -LRB- cord-001207-yjaiybwf 143 27 probiotic probiotic JJ cord-001207-yjaiybwf 143 28 group group NN cord-001207-yjaiybwf 143 29 ) ) -RRB- cord-001207-yjaiybwf 143 30 . . . cord-001207-yjaiybwf 144 1 Within within IN cord-001207-yjaiybwf 144 2 the the DT cord-001207-yjaiybwf 144 3 four four CD cord-001207-yjaiybwf 144 4 groups group NNS cord-001207-yjaiybwf 144 5 of of IN cord-001207-yjaiybwf 144 6 the the DT cord-001207-yjaiybwf 144 7 sows sow NNS cord-001207-yjaiybwf 144 8 ( ( -LRB- cord-001207-yjaiybwf 144 9 one one CD cord-001207-yjaiybwf 144 10 year year NN cord-001207-yjaiybwf 144 11 old old JJ cord-001207-yjaiybwf 144 12 ) ) -RRB- cord-001207-yjaiybwf 145 1 the the DT cord-001207-yjaiybwf 145 2 amount amount NN cord-001207-yjaiybwf 145 3 of of IN cord-001207-yjaiybwf 145 4 mammalian mammalian JJ cord-001207-yjaiybwf 145 5 viruses virus NNS cord-001207-yjaiybwf 145 6 ranged range VBD cord-001207-yjaiybwf 145 7 from from IN cord-001207-yjaiybwf 145 8 8 8 CD cord-001207-yjaiybwf 145 9 % % NN cord-001207-yjaiybwf 145 10 to to TO cord-001207-yjaiybwf 145 11 12 12 CD cord-001207-yjaiybwf 145 12 % % NN cord-001207-yjaiybwf 145 13 . . . cord-001207-yjaiybwf 146 1 In in IN cord-001207-yjaiybwf 146 2 contrast contrast NN cord-001207-yjaiybwf 146 3 to to IN cord-001207-yjaiybwf 146 4 those those DT cord-001207-yjaiybwf 146 5 findings finding NNS cord-001207-yjaiybwf 146 6 , , , cord-001207-yjaiybwf 146 7 the the DT cord-001207-yjaiybwf 146 8 proportion proportion NN cord-001207-yjaiybwf 146 9 of of IN cord-001207-yjaiybwf 146 10 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 146 11 increased increase VBD cord-001207-yjaiybwf 146 12 with with IN cord-001207-yjaiybwf 146 13 the the DT cord-001207-yjaiybwf 146 14 age age NN cord-001207-yjaiybwf 146 15 of of IN cord-001207-yjaiybwf 146 16 the the DT cord-001207-yjaiybwf 146 17 pigs pig NNS cord-001207-yjaiybwf 146 18 . . . cord-001207-yjaiybwf 147 1 In in IN cord-001207-yjaiybwf 147 2 the the DT cord-001207-yjaiybwf 147 3 12 12 CD cord-001207-yjaiybwf 147 4 day day NN cord-001207-yjaiybwf 147 5 - - HYPH cord-001207-yjaiybwf 147 6 old old JJ cord-001207-yjaiybwf 147 7 piglets piglet NNS cord-001207-yjaiybwf 147 8 , , , cord-001207-yjaiybwf 147 9 44 44 CD cord-001207-yjaiybwf 147 10 % % NN cord-001207-yjaiybwf 147 11 ( ( -LRB- cord-001207-yjaiybwf 147 12 control control NN cord-001207-yjaiybwf 147 13 group group NN cord-001207-yjaiybwf 147 14 ) ) -RRB- cord-001207-yjaiybwf 147 15 and and CC cord-001207-yjaiybwf 147 16 22 22 CD cord-001207-yjaiybwf 147 17 % % NN cord-001207-yjaiybwf 147 18 ( ( -LRB- cord-001207-yjaiybwf 147 19 probiotic probiotic JJ cord-001207-yjaiybwf 147 20 group group NN cord-001207-yjaiybwf 147 21 ) ) -RRB- cord-001207-yjaiybwf 147 22 of of IN cord-001207-yjaiybwf 147 23 the the DT cord-001207-yjaiybwf 147 24 reads read NNS cord-001207-yjaiybwf 147 25 relate relate VBP cord-001207-yjaiybwf 147 26 to to IN cord-001207-yjaiybwf 147 27 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 147 28 . . . cord-001207-yjaiybwf 148 1 The the DT cord-001207-yjaiybwf 148 2 percentage percentage NN cord-001207-yjaiybwf 148 3 of of IN cord-001207-yjaiybwf 148 4 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 148 5 increases increase VBZ cord-001207-yjaiybwf 148 6 in in IN cord-001207-yjaiybwf 148 7 the the DT cord-001207-yjaiybwf 148 8 54 54 CD cord-001207-yjaiybwf 148 9 day day NN cord-001207-yjaiybwf 148 10 - - HYPH cord-001207-yjaiybwf 148 11 old old JJ cord-001207-yjaiybwf 148 12 piglets piglet NNS cord-001207-yjaiybwf 148 13 to to IN cord-001207-yjaiybwf 148 14 68 68 CD cord-001207-yjaiybwf 148 15 % % NN cord-001207-yjaiybwf 148 16 ( ( -LRB- cord-001207-yjaiybwf 148 17 control control NN cord-001207-yjaiybwf 148 18 group group NN cord-001207-yjaiybwf 148 19 ) ) -RRB- cord-001207-yjaiybwf 148 20 and and CC cord-001207-yjaiybwf 148 21 72 72 CD cord-001207-yjaiybwf 148 22 % % NN cord-001207-yjaiybwf 148 23 ( ( -LRB- cord-001207-yjaiybwf 148 24 probiotic probiotic JJ cord-001207-yjaiybwf 148 25 group group NN cord-001207-yjaiybwf 148 26 ) ) -RRB- cord-001207-yjaiybwf 148 27 , , , cord-001207-yjaiybwf 148 28 whereas whereas IN cord-001207-yjaiybwf 148 29 approximately approximately RB cord-001207-yjaiybwf 148 30 90 90 CD cord-001207-yjaiybwf 148 31 % % NN cord-001207-yjaiybwf 148 32 of of IN cord-001207-yjaiybwf 148 33 the the DT cord-001207-yjaiybwf 148 34 virus virus NN cord-001207-yjaiybwf 148 35 reads read VBZ cord-001207-yjaiybwf 148 36 belong belong VBP cord-001207-yjaiybwf 148 37 to to IN cord-001207-yjaiybwf 148 38 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 148 39 in in IN cord-001207-yjaiybwf 148 40 the the DT cord-001207-yjaiybwf 148 41 four four CD cord-001207-yjaiybwf 148 42 sow sow NN cord-001207-yjaiybwf 148 43 groups group NNS cord-001207-yjaiybwf 148 44 . . . cord-001207-yjaiybwf 149 1 No no DT cord-001207-yjaiybwf 149 2 differences difference NNS cord-001207-yjaiybwf 149 3 in in IN cord-001207-yjaiybwf 149 4 the the DT cord-001207-yjaiybwf 149 5 general general JJ cord-001207-yjaiybwf 149 6 composition composition NN cord-001207-yjaiybwf 149 7 of of IN cord-001207-yjaiybwf 149 8 virus virus NN cord-001207-yjaiybwf 149 9 families family NNS cord-001207-yjaiybwf 149 10 or or CC cord-001207-yjaiybwf 149 11 the the DT cord-001207-yjaiybwf 149 12 respective respective JJ cord-001207-yjaiybwf 149 13 hosts host NNS cord-001207-yjaiybwf 149 14 were be VBD cord-001207-yjaiybwf 149 15 evident evident JJ cord-001207-yjaiybwf 149 16 , , , cord-001207-yjaiybwf 149 17 when when WRB cord-001207-yjaiybwf 149 18 the the DT cord-001207-yjaiybwf 149 19 probiotic probiotic JJ cord-001207-yjaiybwf 149 20 group group NN cord-001207-yjaiybwf 149 21 was be VBD cord-001207-yjaiybwf 149 22 compared compare VBN cord-001207-yjaiybwf 149 23 to to IN cord-001207-yjaiybwf 149 24 the the DT cord-001207-yjaiybwf 149 25 control control NN cord-001207-yjaiybwf 149 26 group group NN cord-001207-yjaiybwf 149 27 . . . cord-001207-yjaiybwf 150 1 In in IN cord-001207-yjaiybwf 150 2 overall overall JJ cord-001207-yjaiybwf 150 3 , , , cord-001207-yjaiybwf 150 4 sequences sequence NNS cord-001207-yjaiybwf 150 5 with with IN cord-001207-yjaiybwf 150 6 significant significant JJ cord-001207-yjaiybwf 150 7 identities identity NNS cord-001207-yjaiybwf 150 8 to to IN cord-001207-yjaiybwf 150 9 524 524 CD cord-001207-yjaiybwf 150 10 known know VBN cord-001207-yjaiybwf 150 11 bacteriophage bacteriophage NN cord-001207-yjaiybwf 150 12 species specie NNS cord-001207-yjaiybwf 150 13 were be VBD cord-001207-yjaiybwf 150 14 detected detect VBN cord-001207-yjaiybwf 150 15 . . . cord-001207-yjaiybwf 151 1 The the DT cord-001207-yjaiybwf 151 2 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 151 3 most most RBS cord-001207-yjaiybwf 151 4 abundant abundant JJ cord-001207-yjaiybwf 151 5 in in IN cord-001207-yjaiybwf 151 6 the the DT cord-001207-yjaiybwf 151 7 eight eight CD cord-001207-yjaiybwf 151 8 samples sample NNS cord-001207-yjaiybwf 151 9 are be VBP cord-001207-yjaiybwf 151 10 shown show VBN cord-001207-yjaiybwf 151 11 in in IN cord-001207-yjaiybwf 151 12 Figure Figure NNP cord-001207-yjaiybwf 151 13 4 4 CD cord-001207-yjaiybwf 151 14 and and CC cord-001207-yjaiybwf 151 15 Table Table NNP cord-001207-yjaiybwf 151 16 _SP cord-001207-yjaiybwf 151 17 S2 S2 NNP cord-001207-yjaiybwf 151 18 . . . cord-001207-yjaiybwf 152 1 In in IN cord-001207-yjaiybwf 152 2 all all DT cord-001207-yjaiybwf 152 3 cases case NNS cord-001207-yjaiybwf 152 4 , , , cord-001207-yjaiybwf 152 5 the the DT cord-001207-yjaiybwf 152 6 bacteriophage bacteriophage NN cord-001207-yjaiybwf 152 7 population population NN cord-001207-yjaiybwf 152 8 is be VBZ cord-001207-yjaiybwf 152 9 dominated dominate VBN cord-001207-yjaiybwf 152 10 by by IN cord-001207-yjaiybwf 152 11 9 9 CD cord-001207-yjaiybwf 152 12 to to TO cord-001207-yjaiybwf 152 13 16 16 CD cord-001207-yjaiybwf 152 14 species specie NNS cord-001207-yjaiybwf 152 15 , , , cord-001207-yjaiybwf 152 16 which which WDT cord-001207-yjaiybwf 152 17 represent represent VBP cord-001207-yjaiybwf 152 18 76 76 CD cord-001207-yjaiybwf 152 19 - - SYM cord-001207-yjaiybwf 152 20 90 90 CD cord-001207-yjaiybwf 152 21 % % NN cord-001207-yjaiybwf 152 22 of of IN cord-001207-yjaiybwf 152 23 all all DT cord-001207-yjaiybwf 152 24 bacteriophage bacteriophage NN cord-001207-yjaiybwf 152 25 reads read VBZ cord-001207-yjaiybwf 152 26 of of IN cord-001207-yjaiybwf 152 27 the the DT cord-001207-yjaiybwf 152 28 respective respective JJ cord-001207-yjaiybwf 152 29 sample sample NN cord-001207-yjaiybwf 152 30 . . . cord-001207-yjaiybwf 153 1 The the DT cord-001207-yjaiybwf 153 2 most most RBS cord-001207-yjaiybwf 153 3 abundant abundant JJ cord-001207-yjaiybwf 153 4 phages phage NNS cord-001207-yjaiybwf 153 5 as as IN cord-001207-yjaiybwf 153 6 identified identify VBN cord-001207-yjaiybwf 153 7 by by IN cord-001207-yjaiybwf 153 8 the the DT cord-001207-yjaiybwf 153 9 highest high JJS cord-001207-yjaiybwf 153 10 number number NN cord-001207-yjaiybwf 153 11 of of IN cord-001207-yjaiybwf 153 12 reads read NNS cord-001207-yjaiybwf 153 13 with with IN cord-001207-yjaiybwf 153 14 sequence sequence NN cord-001207-yjaiybwf 153 15 identities identity NNS cord-001207-yjaiybwf 153 16 to to IN cord-001207-yjaiybwf 153 17 known know VBN cord-001207-yjaiybwf 153 18 bacteriophage bacteriophage NN cord-001207-yjaiybwf 153 19 genomes genome NNS cord-001207-yjaiybwf 153 20 are be VBP cord-001207-yjaiybwf 153 21 Lactococcus Lactococcus NNP cord-001207-yjaiybwf 153 22 phage phage NN cord-001207-yjaiybwf 153 23 1706 1706 CD cord-001207-yjaiybwf 153 24 , , , cord-001207-yjaiybwf 153 25 Dragonflyassociated Dragonflyassociated NNP cord-001207-yjaiybwf 153 26 microphage microphage NN cord-001207-yjaiybwf 153 27 1 1 CD cord-001207-yjaiybwf 153 28 , , , cord-001207-yjaiybwf 153 29 Chlamydia Chlamydia NNP cord-001207-yjaiybwf 153 30 phages phage NNS cord-001207-yjaiybwf 153 31 4 4 CD cord-001207-yjaiybwf 153 32 , , , cord-001207-yjaiybwf 153 33 Chp1 Chp1 NNP cord-001207-yjaiybwf 153 34 and and CC cord-001207-yjaiybwf 153 35 Chp2 Chp2 NNP cord-001207-yjaiybwf 153 36 , , , cord-001207-yjaiybwf 153 37 Bdellovibrio Bdellovibrio NNP cord-001207-yjaiybwf 153 38 phage phage NN cord-001207-yjaiybwf 153 39 phiMH2 phimh2 CD cord-001207-yjaiybwf 153 40 K K NNP cord-001207-yjaiybwf 153 41 , , , cord-001207-yjaiybwf 153 42 Spiroplasma Spiroplasma NNP cord-001207-yjaiybwf 153 43 phage phage NN cord-001207-yjaiybwf 153 44 4 4 CD cord-001207-yjaiybwf 153 45 , , , cord-001207-yjaiybwf 153 46 Microvirus Microvirus NNP cord-001207-yjaiybwf 153 47 CA82 CA82 NNP cord-001207-yjaiybwf 153 48 as as RB cord-001207-yjaiybwf 153 49 well well RB cord-001207-yjaiybwf 153 50 as as IN cord-001207-yjaiybwf 153 51 Enterococcous Enterococcous NNP cord-001207-yjaiybwf 153 52 phages phage NNS cord-001207-yjaiybwf 153 53 EFAP-1 EFAP-1 NNP cord-001207-yjaiybwf 153 54 and and CC cord-001207-yjaiybwf 154 1 EFRM31 EFRM31 NNP cord-001207-yjaiybwf 154 2 . . . cord-001207-yjaiybwf 155 1 A a DT cord-001207-yjaiybwf 155 2 comparison comparison NN cord-001207-yjaiybwf 155 3 between between IN cord-001207-yjaiybwf 155 4 the the DT cord-001207-yjaiybwf 155 5 bacteriophage bacteriophage NN cord-001207-yjaiybwf 155 6 populations population NNS cord-001207-yjaiybwf 155 7 of of IN cord-001207-yjaiybwf 155 8 the the DT cord-001207-yjaiybwf 155 9 specific specific JJ cord-001207-yjaiybwf 155 10 samples sample NNS cord-001207-yjaiybwf 155 11 indicated indicate VBD cord-001207-yjaiybwf 155 12 that that IN cord-001207-yjaiybwf 155 13 many many JJ cord-001207-yjaiybwf 155 14 of of IN cord-001207-yjaiybwf 155 15 the the DT cord-001207-yjaiybwf 155 16 most most RBS cord-001207-yjaiybwf 155 17 abundant abundant JJ cord-001207-yjaiybwf 155 18 bacteriophage bacteriophage NN cord-001207-yjaiybwf 155 19 species specie NNS cord-001207-yjaiybwf 155 20 are be VBP cord-001207-yjaiybwf 155 21 present present JJ cord-001207-yjaiybwf 155 22 in in IN cord-001207-yjaiybwf 155 23 all all DT cord-001207-yjaiybwf 155 24 samples sample NNS cord-001207-yjaiybwf 155 25 , , , cord-001207-yjaiybwf 155 26 however however RB cord-001207-yjaiybwf 155 27 , , , cord-001207-yjaiybwf 155 28 with with IN cord-001207-yjaiybwf 155 29 different different JJ cord-001207-yjaiybwf 155 30 relative relative JJ cord-001207-yjaiybwf 155 31 frequency frequency NN cord-001207-yjaiybwf 155 32 . . . cord-001207-yjaiybwf 156 1 Apart apart RB cord-001207-yjaiybwf 156 2 from from IN cord-001207-yjaiybwf 156 3 that that DT cord-001207-yjaiybwf 156 4 , , , cord-001207-yjaiybwf 156 5 the the DT cord-001207-yjaiybwf 156 6 composition composition NN cord-001207-yjaiybwf 156 7 of of IN cord-001207-yjaiybwf 156 8 the the DT cord-001207-yjaiybwf 156 9 faecal faecal JJ cord-001207-yjaiybwf 156 10 virome virome NN cord-001207-yjaiybwf 156 11 with with IN cord-001207-yjaiybwf 156 12 regard regard NN cord-001207-yjaiybwf 156 13 to to IN cord-001207-yjaiybwf 156 14 bacteriophage bacteriophage NN cord-001207-yjaiybwf 156 15 species specie NNS cord-001207-yjaiybwf 156 16 was be VBD cord-001207-yjaiybwf 156 17 relatively relatively RB cord-001207-yjaiybwf 156 18 variable variable JJ cord-001207-yjaiybwf 156 19 between between IN cord-001207-yjaiybwf 156 20 the the DT cord-001207-yjaiybwf 156 21 samples sample NNS cord-001207-yjaiybwf 156 22 and and CC cord-001207-yjaiybwf 156 23 every every DT cord-001207-yjaiybwf 156 24 sample sample NN cord-001207-yjaiybwf 156 25 contained contain VBD cord-001207-yjaiybwf 156 26 its -PRON- PRP$ cord-001207-yjaiybwf 156 27 unique unique JJ cord-001207-yjaiybwf 156 28 collection collection NN cord-001207-yjaiybwf 156 29 of of IN cord-001207-yjaiybwf 156 30 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 156 31 . . . cord-001207-yjaiybwf 157 1 No no DT cord-001207-yjaiybwf 157 2 consistent consistent JJ cord-001207-yjaiybwf 157 3 differences difference NNS cord-001207-yjaiybwf 157 4 between between IN cord-001207-yjaiybwf 157 5 age age NN cord-001207-yjaiybwf 157 6 groups group NNS cord-001207-yjaiybwf 157 7 and and CC cord-001207-yjaiybwf 157 8 feeding feed VBG cord-001207-yjaiybwf 157 9 groups group NNS cord-001207-yjaiybwf 157 10 were be VBD cord-001207-yjaiybwf 157 11 obvious obvious JJ cord-001207-yjaiybwf 157 12 when when WRB cord-001207-yjaiybwf 157 13 the the DT cord-001207-yjaiybwf 157 14 abundance abundance NN cord-001207-yjaiybwf 157 15 of of IN cord-001207-yjaiybwf 157 16 bacteriophage bacteriophage NN cord-001207-yjaiybwf 157 17 species specie NNS cord-001207-yjaiybwf 157 18 was be VBD cord-001207-yjaiybwf 157 19 analyzed analyze VBN cord-001207-yjaiybwf 157 20 . . . cord-001207-yjaiybwf 158 1 Interestingly interestingly RB cord-001207-yjaiybwf 158 2 , , , cord-001207-yjaiybwf 158 3 the the DT cord-001207-yjaiybwf 158 4 sample sample NN cord-001207-yjaiybwf 158 5 taken take VBN cord-001207-yjaiybwf 158 6 at at IN cord-001207-yjaiybwf 158 7 day day NN cord-001207-yjaiybwf 158 8 14 14 CD cord-001207-yjaiybwf 158 9 post post NN cord-001207-yjaiybwf 158 10 partum partum NN cord-001207-yjaiybwf 158 11 from from IN cord-001207-yjaiybwf 158 12 the the DT cord-001207-yjaiybwf 158 13 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 158 14 faecium faecium NN cord-001207-yjaiybwf 158 15 - - HYPH cord-001207-yjaiybwf 158 16 fed fed NNP cord-001207-yjaiybwf 158 17 sows sow NNS cord-001207-yjaiybwf 158 18 contained contain VBD cord-001207-yjaiybwf 158 19 relatively relatively RB cord-001207-yjaiybwf 158 20 high high JJ cord-001207-yjaiybwf 158 21 amounts amount NNS cord-001207-yjaiybwf 158 22 of of IN cord-001207-yjaiybwf 158 23 the the DT cord-001207-yjaiybwf 158 24 Enterococcous Enterococcous NNP cord-001207-yjaiybwf 158 25 phages phage NNS cord-001207-yjaiybwf 158 26 EFAP-1 EFAP-1 NNP cord-001207-yjaiybwf 158 27 ( ( -LRB- cord-001207-yjaiybwf 158 28 10.8 10.8 CD cord-001207-yjaiybwf 158 29 % % NN cord-001207-yjaiybwf 158 30 ) ) -RRB- cord-001207-yjaiybwf 158 31 and and CC cord-001207-yjaiybwf 158 32 EFRM31 EFRM31 NNP cord-001207-yjaiybwf 158 33 ( ( -LRB- cord-001207-yjaiybwf 158 34 7.0 7.0 CD cord-001207-yjaiybwf 158 35 % % NN cord-001207-yjaiybwf 158 36 ) ) -RRB- cord-001207-yjaiybwf 158 37 , , , cord-001207-yjaiybwf 158 38 which which WDT cord-001207-yjaiybwf 158 39 were be VBD cord-001207-yjaiybwf 158 40 only only RB cord-001207-yjaiybwf 158 41 sporadically sporadically RB cord-001207-yjaiybwf 158 42 detected detect VBN cord-001207-yjaiybwf 158 43 in in IN cord-001207-yjaiybwf 158 44 the the DT cord-001207-yjaiybwf 158 45 other other JJ cord-001207-yjaiybwf 158 46 groups group NNS cord-001207-yjaiybwf 158 47 ( ( -LRB- cord-001207-yjaiybwf 158 48 0.02 0.02 CD cord-001207-yjaiybwf 158 49 % % NN cord-001207-yjaiybwf 158 50 to to TO cord-001207-yjaiybwf 158 51 0.6 0.6 CD cord-001207-yjaiybwf 158 52 % % NN cord-001207-yjaiybwf 158 53 ) ) -RRB- cord-001207-yjaiybwf 158 54 . . . cord-001207-yjaiybwf 159 1 By by IN cord-001207-yjaiybwf 159 2 analysis analysis NN cord-001207-yjaiybwf 159 3 of of IN cord-001207-yjaiybwf 159 4 all all DT cord-001207-yjaiybwf 159 5 virus virus NN cord-001207-yjaiybwf 159 6 reads read VBZ cord-001207-yjaiybwf 159 7 excluding exclude VBG cord-001207-yjaiybwf 159 8 the the DT cord-001207-yjaiybwf 159 9 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 159 10 , , , cord-001207-yjaiybwf 159 11 sequences sequence NNS cord-001207-yjaiybwf 159 12 with with IN cord-001207-yjaiybwf 159 13 significant significant JJ cord-001207-yjaiybwf 159 14 identities identity NNS cord-001207-yjaiybwf 159 15 to to IN cord-001207-yjaiybwf 159 16 205 205 CD cord-001207-yjaiybwf 159 17 known know VBN cord-001207-yjaiybwf 159 18 virus virus NN cord-001207-yjaiybwf 159 19 species specie NNS cord-001207-yjaiybwf 159 20 were be VBD cord-001207-yjaiybwf 159 21 detected detect VBN cord-001207-yjaiybwf 159 22 . . . cord-001207-yjaiybwf 160 1 Among among IN cord-001207-yjaiybwf 160 2 that that DT cord-001207-yjaiybwf 160 3 , , , cord-001207-yjaiybwf 160 4 92.9 92.9 CD cord-001207-yjaiybwf 160 5 % % NN cord-001207-yjaiybwf 160 6 of of IN cord-001207-yjaiybwf 160 7 the the DT cord-001207-yjaiybwf 160 8 sequences sequence NNS cord-001207-yjaiybwf 160 9 belonged belong VBD cord-001207-yjaiybwf 160 10 to to IN cord-001207-yjaiybwf 160 11 viruses virus NNS cord-001207-yjaiybwf 160 12 infecting infect VBG cord-001207-yjaiybwf 160 13 mammalian mammalian JJ cord-001207-yjaiybwf 160 14 animals animal NNS cord-001207-yjaiybwf 160 15 . . . cord-001207-yjaiybwf 161 1 This this DT cord-001207-yjaiybwf 161 2 percentage percentage NN cord-001207-yjaiybwf 161 3 of of IN cord-001207-yjaiybwf 161 4 mam- mam- JJ cord-001207-yjaiybwf 161 5 malian malian JJ cord-001207-yjaiybwf 161 6 viruses virus NNS cord-001207-yjaiybwf 161 7 decreased decrease VBD cord-001207-yjaiybwf 161 8 with with IN cord-001207-yjaiybwf 161 9 age age NN cord-001207-yjaiybwf 161 10 , , , cord-001207-yjaiybwf 161 11 with with IN cord-001207-yjaiybwf 161 12 an an DT cord-001207-yjaiybwf 161 13 average average NN cord-001207-yjaiybwf 161 14 of of IN cord-001207-yjaiybwf 161 15 99.1 99.1 CD cord-001207-yjaiybwf 161 16 % % NN cord-001207-yjaiybwf 161 17 in in IN cord-001207-yjaiybwf 161 18 the the DT cord-001207-yjaiybwf 161 19 12 12 CD cord-001207-yjaiybwf 161 20 day day NN cord-001207-yjaiybwf 161 21 - - HYPH cord-001207-yjaiybwf 161 22 old old JJ cord-001207-yjaiybwf 161 23 piglet piglet NN cord-001207-yjaiybwf 161 24 group group NN cord-001207-yjaiybwf 161 25 , , , cord-001207-yjaiybwf 161 26 91.8 91.8 CD cord-001207-yjaiybwf 161 27 % % NN cord-001207-yjaiybwf 161 28 in in IN cord-001207-yjaiybwf 161 29 the the DT cord-001207-yjaiybwf 161 30 54 54 CD cord-001207-yjaiybwf 161 31 day day NN cord-001207-yjaiybwf 161 32 - - HYPH cord-001207-yjaiybwf 161 33 old old JJ cord-001207-yjaiybwf 161 34 piglet piglet NN cord-001207-yjaiybwf 161 35 group group NN cord-001207-yjaiybwf 161 36 and and CC cord-001207-yjaiybwf 161 37 79.0 79.0 CD cord-001207-yjaiybwf 161 38 % % NN cord-001207-yjaiybwf 161 39 in in IN cord-001207-yjaiybwf 161 40 the the DT cord-001207-yjaiybwf 161 41 sows sow NNS cord-001207-yjaiybwf 161 42 . . . cord-001207-yjaiybwf 162 1 The the DT cord-001207-yjaiybwf 162 2 relative relative JJ cord-001207-yjaiybwf 162 3 percentage percentage NN cord-001207-yjaiybwf 162 4 of of IN cord-001207-yjaiybwf 162 5 the the DT cord-001207-yjaiybwf 162 6 most most RBS cord-001207-yjaiybwf 162 7 abundant abundant JJ cord-001207-yjaiybwf 162 8 mammalian mammalian JJ cord-001207-yjaiybwf 162 9 virus virus NN cord-001207-yjaiybwf 162 10 genera genera VBP cord-001207-yjaiybwf 162 11 in in IN cord-001207-yjaiybwf 162 12 the the DT cord-001207-yjaiybwf 162 13 eight eight CD cord-001207-yjaiybwf 162 14 samples sample NNS cord-001207-yjaiybwf 162 15 is be VBZ cord-001207-yjaiybwf 162 16 shown show VBN cord-001207-yjaiybwf 162 17 in in IN cord-001207-yjaiybwf 162 18 Figure Figure NNP cord-001207-yjaiybwf 162 19 5 5 CD cord-001207-yjaiybwf 162 20 and and CC cord-001207-yjaiybwf 162 21 dant dant NNP cord-001207-yjaiybwf 162 22 mammalian mammalian JJ cord-001207-yjaiybwf 162 23 viruses virus NNS cord-001207-yjaiybwf 162 24 . . . cord-001207-yjaiybwf 163 1 Among among IN cord-001207-yjaiybwf 163 2 the the DT cord-001207-yjaiybwf 163 3 ' ' `` cord-001207-yjaiybwf 163 4 ' ' `` cord-001207-yjaiybwf 163 5 circovirus circovirus JJ cord-001207-yjaiybwf 163 6 - - HYPH cord-001207-yjaiybwf 163 7 like like JJ cord-001207-yjaiybwf 163 8 ' ' '' cord-001207-yjaiybwf 163 9 ' ' '' cord-001207-yjaiybwf 163 10 viruses virus NNS cord-001207-yjaiybwf 163 11 , , , cord-001207-yjaiybwf 163 12 sequences sequence NNS cord-001207-yjaiybwf 163 13 with with IN cord-001207-yjaiybwf 163 14 highest high JJS cord-001207-yjaiybwf 163 15 identities identity NNS cord-001207-yjaiybwf 163 16 to to IN cord-001207-yjaiybwf 163 17 the the DT cord-001207-yjaiybwf 163 18 viruses virus NNS cord-001207-yjaiybwf 163 19 CB CB NNP cord-001207-yjaiybwf 164 1 -A -A : cord-001207-yjaiybwf 164 2 and and CC cord-001207-yjaiybwf 164 3 RW RW NNP cord-001207-yjaiybwf 164 4 - - HYPH cord-001207-yjaiybwf 164 5 A a NN cord-001207-yjaiybwf 164 6 were be VBD cord-001207-yjaiybwf 164 7 most most RBS cord-001207-yjaiybwf 164 8 often often RB cord-001207-yjaiybwf 164 9 detected detect VBN cord-001207-yjaiybwf 164 10 . . . cord-001207-yjaiybwf 165 1 No no DT cord-001207-yjaiybwf 165 2 consistent consistent JJ cord-001207-yjaiybwf 165 3 differences difference NNS cord-001207-yjaiybwf 165 4 were be VBD cord-001207-yjaiybwf 165 5 obvious obvious JJ cord-001207-yjaiybwf 165 6 between between IN cord-001207-yjaiybwf 165 7 the the DT cord-001207-yjaiybwf 165 8 group group NN cord-001207-yjaiybwf 165 9 fed feed VBN cord-001207-yjaiybwf 165 10 with with IN cord-001207-yjaiybwf 165 11 the the DT cord-001207-yjaiybwf 165 12 probiotic probiotic JJ cord-001207-yjaiybwf 165 13 bacterium bacterium NN cord-001207-yjaiybwf 165 14 and and CC cord-001207-yjaiybwf 165 15 the the DT cord-001207-yjaiybwf 165 16 control control NN cord-001207-yjaiybwf 165 17 group group NN cord-001207-yjaiybwf 165 18 . . . cord-001207-yjaiybwf 166 1 However however RB cord-001207-yjaiybwf 166 2 , , , cord-001207-yjaiybwf 166 3 a a DT cord-001207-yjaiybwf 166 4 relatively relatively RB cord-001207-yjaiybwf 166 5 high high JJ cord-001207-yjaiybwf 166 6 proportion proportion NN cord-001207-yjaiybwf 166 7 of of IN cord-001207-yjaiybwf 166 8 mamastrovirus mamastrovirus NNP cord-001207-yjaiybwf 166 9 sequences sequence NNS cord-001207-yjaiybwf 166 10 ( ( -LRB- cord-001207-yjaiybwf 166 11 16.3 16.3 CD cord-001207-yjaiybwf 166 12 % % NN cord-001207-yjaiybwf 166 13 ) ) -RRB- cord-001207-yjaiybwf 166 14 was be VBD cord-001207-yjaiybwf 166 15 detected detect VBN cord-001207-yjaiybwf 166 16 in in IN cord-001207-yjaiybwf 166 17 the the DT cord-001207-yjaiybwf 166 18 sample sample NN cord-001207-yjaiybwf 166 19 derived derive VBN cord-001207-yjaiybwf 166 20 from from IN cord-001207-yjaiybwf 166 21 the the DT cord-001207-yjaiybwf 166 22 54 54 CD cord-001207-yjaiybwf 166 23 day day NN cord-001207-yjaiybwf 166 24 - - HYPH cord-001207-yjaiybwf 166 25 old old JJ cord-001207-yjaiybwf 166 26 piglets piglet NNS cord-001207-yjaiybwf 166 27 ; ; : cord-001207-yjaiybwf 166 28 while while IN cord-001207-yjaiybwf 166 29 this this DT cord-001207-yjaiybwf 166 30 virus virus NN cord-001207-yjaiybwf 166 31 was be VBD cord-001207-yjaiybwf 166 32 not not RB cord-001207-yjaiybwf 166 33 detected detect VBN cord-001207-yjaiybwf 166 34 in in IN cord-001207-yjaiybwf 166 35 the the DT cord-001207-yjaiybwf 166 36 other other JJ cord-001207-yjaiybwf 166 37 groups group NNS cord-001207-yjaiybwf 166 38 ( ( -LRB- cord-001207-yjaiybwf 166 39 less less JJR cord-001207-yjaiybwf 166 40 than than IN cord-001207-yjaiybwf 166 41 2 2 CD cord-001207-yjaiybwf 166 42 reads read NNS cord-001207-yjaiybwf 166 43 per per IN cord-001207-yjaiybwf 166 44 sample sample NN cord-001207-yjaiybwf 166 45 ) ) -RRB- cord-001207-yjaiybwf 166 46 . . . cord-001207-yjaiybwf 167 1 The the DT cord-001207-yjaiybwf 167 2 calculation calculation NN cord-001207-yjaiybwf 167 3 of of IN cord-001207-yjaiybwf 167 4 the the DT cord-001207-yjaiybwf 167 5 Shannon Shannon NNP cord-001207-yjaiybwf 167 6 index index NN cord-001207-yjaiybwf 167 7 was be VBD cord-001207-yjaiybwf 167 8 used use VBN cord-001207-yjaiybwf 167 9 to to TO cord-001207-yjaiybwf 167 10 assess assess VB cord-001207-yjaiybwf 167 11 the the DT cord-001207-yjaiybwf 167 12 diversity diversity NN cord-001207-yjaiybwf 167 13 of of IN cord-001207-yjaiybwf 167 14 the the DT cord-001207-yjaiybwf 167 15 sequences sequence NNS cord-001207-yjaiybwf 167 16 detected detect VBN cord-001207-yjaiybwf 167 17 in in IN cord-001207-yjaiybwf 167 18 the the DT cord-001207-yjaiybwf 167 19 specific specific JJ cord-001207-yjaiybwf 167 20 samples sample NNS cord-001207-yjaiybwf 167 21 ( ( -LRB- cord-001207-yjaiybwf 167 22 Table Table NNP cord-001207-yjaiybwf 167 23 3 3 CD cord-001207-yjaiybwf 167 24 ) ) -RRB- cord-001207-yjaiybwf 167 25 . . . cord-001207-yjaiybwf 168 1 Generally generally RB cord-001207-yjaiybwf 168 2 , , , cord-001207-yjaiybwf 168 3 comparison comparison NN cord-001207-yjaiybwf 168 4 of of IN cord-001207-yjaiybwf 168 5 Shannon Shannon NNP cord-001207-yjaiybwf 168 6 indexes index NNS cord-001207-yjaiybwf 168 7 between between IN cord-001207-yjaiybwf 168 8 piglets piglet NNS cord-001207-yjaiybwf 168 9 and and CC cord-001207-yjaiybwf 168 10 sows sow NNS cord-001207-yjaiybwf 168 11 indicated indicate VBD cord-001207-yjaiybwf 168 12 that that IN cord-001207-yjaiybwf 168 13 the the DT cord-001207-yjaiybwf 168 14 diversity diversity NN cord-001207-yjaiybwf 168 15 increased increase VBD cord-001207-yjaiybwf 168 16 with with IN cord-001207-yjaiybwf 168 17 age age NN cord-001207-yjaiybwf 168 18 . . . cord-001207-yjaiybwf 169 1 When when WRB cord-001207-yjaiybwf 169 2 only only RB cord-001207-yjaiybwf 169 3 the the DT cord-001207-yjaiybwf 169 4 bacteriophage bacteriophage NN cord-001207-yjaiybwf 169 5 sequences sequence NNS cord-001207-yjaiybwf 169 6 were be VBD cord-001207-yjaiybwf 169 7 analysed analyse VBN cord-001207-yjaiybwf 169 8 , , , cord-001207-yjaiybwf 169 9 the the DT cord-001207-yjaiybwf 169 10 average average JJ cord-001207-yjaiybwf 169 11 Shannon Shannon NNP cord-001207-yjaiybwf 169 12 index index NN cord-001207-yjaiybwf 169 13 of of IN cord-001207-yjaiybwf 169 14 the the DT cord-001207-yjaiybwf 169 15 piglet piglet NN cord-001207-yjaiybwf 169 16 groups group NNS cord-001207-yjaiybwf 169 17 was be VBD cord-001207-yjaiybwf 169 18 1.3 1.3 CD cord-001207-yjaiybwf 169 19 and and CC cord-001207-yjaiybwf 169 20 that that DT cord-001207-yjaiybwf 169 21 of of IN cord-001207-yjaiybwf 169 22 the the DT cord-001207-yjaiybwf 169 23 sows sow NNS cord-001207-yjaiybwf 169 24 1.7 1.7 CD cord-001207-yjaiybwf 169 25 . . . cord-001207-yjaiybwf 170 1 For for IN cord-001207-yjaiybwf 170 2 the the DT cord-001207-yjaiybwf 170 3 mammalian mammalian JJ cord-001207-yjaiybwf 170 4 virus virus NN cord-001207-yjaiybwf 170 5 sequences sequence NNS cord-001207-yjaiybwf 170 6 , , , cord-001207-yjaiybwf 170 7 the the DT cord-001207-yjaiybwf 170 8 average average JJ cord-001207-yjaiybwf 170 9 Shannon Shannon NNP cord-001207-yjaiybwf 170 10 index index NN cord-001207-yjaiybwf 170 11 for for IN cord-001207-yjaiybwf 170 12 the the DT cord-001207-yjaiybwf 170 13 piglets piglet NNS cord-001207-yjaiybwf 170 14 was be VBD cord-001207-yjaiybwf 170 15 1.9 1.9 CD cord-001207-yjaiybwf 170 16 and and CC cord-001207-yjaiybwf 170 17 that that IN cord-001207-yjaiybwf 170 18 for for IN cord-001207-yjaiybwf 170 19 the the DT cord-001207-yjaiybwf 170 20 sows sow NNS cord-001207-yjaiybwf 170 21 3.0 3.0 CD cord-001207-yjaiybwf 170 22 . . . cord-001207-yjaiybwf 171 1 Calculation calculation NN cord-001207-yjaiybwf 171 2 of of IN cord-001207-yjaiybwf 171 3 Bray Bray NNP cord-001207-yjaiybwf 171 4 - - HYPH cord-001207-yjaiybwf 171 5 Curtis Curtis NNP cord-001207-yjaiybwf 171 6 distances distance NNS cord-001207-yjaiybwf 171 7 determined determine VBD cord-001207-yjaiybwf 171 8 similarities similarity NNS cord-001207-yjaiybwf 171 9 of of IN cord-001207-yjaiybwf 171 10 the the DT cord-001207-yjaiybwf 171 11 faecal faecal JJ cord-001207-yjaiybwf 171 12 viromes virome NNS cord-001207-yjaiybwf 171 13 detected detect VBN cord-001207-yjaiybwf 171 14 in in IN cord-001207-yjaiybwf 171 15 the the DT cord-001207-yjaiybwf 171 16 specific specific JJ cord-001207-yjaiybwf 171 17 samples sample NNS cord-001207-yjaiybwf 171 18 . . . cord-001207-yjaiybwf 172 1 Figure figure NN cord-001207-yjaiybwf 172 2 6 6 CD cord-001207-yjaiybwf 172 3 illustrates illustrate NNS cord-001207-yjaiybwf 172 4 clustering clustering NN cord-001207-yjaiybwf 172 5 of of IN cord-001207-yjaiybwf 172 6 samples sample NNS cord-001207-yjaiybwf 172 7 on on IN cord-001207-yjaiybwf 172 8 the the DT cord-001207-yjaiybwf 172 9 basis basis NN cord-001207-yjaiybwf 172 10 of of IN cord-001207-yjaiybwf 172 11 Bray Bray NNP cord-001207-yjaiybwf 172 12 Curtis Curtis NNP cord-001207-yjaiybwf 172 13 distance distance NN cord-001207-yjaiybwf 172 14 calculated calculate VBN cord-001207-yjaiybwf 172 15 by by IN cord-001207-yjaiybwf 172 16 abundances abundance NNS cord-001207-yjaiybwf 172 17 of of IN cord-001207-yjaiybwf 172 18 species species NN cord-001207-yjaiybwf 172 19 - - HYPH cord-001207-yjaiybwf 172 20 specific specific JJ cord-001207-yjaiybwf 172 21 subsets subset NNS cord-001207-yjaiybwf 172 22 . . . cord-001207-yjaiybwf 173 1 As as IN cord-001207-yjaiybwf 173 2 shown show VBN cord-001207-yjaiybwf 173 3 in in IN cord-001207-yjaiybwf 173 4 the the DT cord-001207-yjaiybwf 173 5 dendrogram dendrogram NN cord-001207-yjaiybwf 173 6 based base VBN cord-001207-yjaiybwf 173 7 on on IN cord-001207-yjaiybwf 173 8 abundances abundance NNS cord-001207-yjaiybwf 173 9 of of IN cord-001207-yjaiybwf 173 10 all all DT cord-001207-yjaiybwf 173 11 virus virus NN cord-001207-yjaiybwf 173 12 species species NN cord-001207-yjaiybwf 173 13 ( ( -LRB- cord-001207-yjaiybwf 173 14 including include VBG cord-001207-yjaiybwf 173 15 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 173 16 ) ) -RRB- cord-001207-yjaiybwf 173 17 , , , cord-001207-yjaiybwf 173 18 a a DT cord-001207-yjaiybwf 173 19 grouping grouping NN cord-001207-yjaiybwf 173 20 according accord VBG cord-001207-yjaiybwf 173 21 to to IN cord-001207-yjaiybwf 173 22 age age NN cord-001207-yjaiybwf 173 23 is be VBZ cord-001207-yjaiybwf 173 24 evident evident JJ cord-001207-yjaiybwf 173 25 ( ( -LRB- cord-001207-yjaiybwf 173 26 Fig fig NN cord-001207-yjaiybwf 173 27 . . . cord-001207-yjaiybwf 173 28 6A 6a CD cord-001207-yjaiybwf 173 29 ) ) -RRB- cord-001207-yjaiybwf 173 30 . . . cord-001207-yjaiybwf 174 1 The the DT cord-001207-yjaiybwf 174 2 two two CD cord-001207-yjaiybwf 174 3 samples sample NNS cord-001207-yjaiybwf 174 4 taken take VBN cord-001207-yjaiybwf 174 5 from from IN cord-001207-yjaiybwf 174 6 the the DT cord-001207-yjaiybwf 174 7 12 12 CD cord-001207-yjaiybwf 174 8 day day NN cord-001207-yjaiybwf 174 9 - - HYPH cord-001207-yjaiybwf 174 10 old old JJ cord-001207-yjaiybwf 174 11 piglets piglet NNS cord-001207-yjaiybwf 174 12 cluster cluster NN cord-001207-yjaiybwf 174 13 closely closely RB cord-001207-yjaiybwf 174 14 together together RB cord-001207-yjaiybwf 174 15 and and CC cord-001207-yjaiybwf 174 16 are be VBP cord-001207-yjaiybwf 174 17 separated separate VBN cord-001207-yjaiybwf 174 18 from from IN cord-001207-yjaiybwf 174 19 the the DT cord-001207-yjaiybwf 174 20 other other JJ cord-001207-yjaiybwf 174 21 samples sample NNS cord-001207-yjaiybwf 174 22 . . . cord-001207-yjaiybwf 175 1 Among among IN cord-001207-yjaiybwf 175 2 these these DT cord-001207-yjaiybwf 175 3 other other JJ cord-001207-yjaiybwf 175 4 samples sample NNS cord-001207-yjaiybwf 175 5 , , , cord-001207-yjaiybwf 175 6 the the DT cord-001207-yjaiybwf 175 7 two two CD cord-001207-yjaiybwf 175 8 samples sample NNS cord-001207-yjaiybwf 175 9 taken take VBN cord-001207-yjaiybwf 175 10 from from IN cord-001207-yjaiybwf 175 11 the the DT cord-001207-yjaiybwf 175 12 54 54 CD cord-001207-yjaiybwf 175 13 day day NN cord-001207-yjaiybwf 175 14 - - HYPH cord-001207-yjaiybwf 175 15 old old JJ cord-001207-yjaiybwf 175 16 piglets piglet NNS cord-001207-yjaiybwf 175 17 form form VBP cord-001207-yjaiybwf 175 18 one one CD cord-001207-yjaiybwf 175 19 separate separate JJ cord-001207-yjaiybwf 175 20 branch branch NN cord-001207-yjaiybwf 175 21 , , , cord-001207-yjaiybwf 175 22 whereas whereas IN cord-001207-yjaiybwf 175 23 the the DT cord-001207-yjaiybwf 175 24 four four CD cord-001207-yjaiybwf 175 25 samples sample NNS cord-001207-yjaiybwf 175 26 of of IN cord-001207-yjaiybwf 175 27 the the DT cord-001207-yjaiybwf 175 28 sows sow NNS cord-001207-yjaiybwf 175 29 are be VBP cord-001207-yjaiybwf 175 30 all all DT cord-001207-yjaiybwf 175 31 contained contain VBN cord-001207-yjaiybwf 175 32 in in IN cord-001207-yjaiybwf 175 33 the the DT cord-001207-yjaiybwf 175 34 other other JJ cord-001207-yjaiybwf 175 35 branch branch NN cord-001207-yjaiybwf 175 36 . . . cord-001207-yjaiybwf 176 1 A a DT cord-001207-yjaiybwf 176 2 branching branching NN cord-001207-yjaiybwf 176 3 according accord VBG cord-001207-yjaiybwf 176 4 to to IN cord-001207-yjaiybwf 176 5 the the DT cord-001207-yjaiybwf 176 6 feeding feeding NN cord-001207-yjaiybwf 176 7 group group NN cord-001207-yjaiybwf 176 8 is be VBZ cord-001207-yjaiybwf 176 9 not not RB cord-001207-yjaiybwf 176 10 evident evident JJ cord-001207-yjaiybwf 176 11 from from IN cord-001207-yjaiybwf 176 12 this this DT cord-001207-yjaiybwf 176 13 dendrogram dendrogram NN cord-001207-yjaiybwf 176 14 . . . cord-001207-yjaiybwf 177 1 The the DT cord-001207-yjaiybwf 177 2 same same JJ cord-001207-yjaiybwf 177 3 grouping grouping NN cord-001207-yjaiybwf 177 4 is be VBZ cord-001207-yjaiybwf 177 5 evident evident JJ cord-001207-yjaiybwf 177 6 , , , cord-001207-yjaiybwf 177 7 when when WRB cord-001207-yjaiybwf 177 8 only only RB cord-001207-yjaiybwf 177 9 the the DT cord-001207-yjaiybwf 177 10 mammalian mammalian JJ cord-001207-yjaiybwf 177 11 virus virus NN cord-001207-yjaiybwf 177 12 sequences sequence NNS cord-001207-yjaiybwf 177 13 are be VBP cord-001207-yjaiybwf 177 14 analysed analyse VBN cord-001207-yjaiybwf 178 1 ( ( -LRB- cord-001207-yjaiybwf 178 2 Fig Fig NNP cord-001207-yjaiybwf 178 3 . . . cord-001207-yjaiybwf 178 4 6B 6b CD cord-001207-yjaiybwf 178 5 ) ) -RRB- cord-001207-yjaiybwf 178 6 . . . cord-001207-yjaiybwf 179 1 The the DT cord-001207-yjaiybwf 179 2 analysis analysis NN cord-001207-yjaiybwf 179 3 of of IN cord-001207-yjaiybwf 179 4 the the DT cord-001207-yjaiybwf 179 5 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 179 6 shows show VBZ cord-001207-yjaiybwf 179 7 no no DT cord-001207-yjaiybwf 179 8 evident evident JJ cord-001207-yjaiybwf 179 9 grouping grouping NN cord-001207-yjaiybwf 179 10 according accord VBG cord-001207-yjaiybwf 179 11 to to IN cord-001207-yjaiybwf 179 12 age age NN cord-001207-yjaiybwf 179 13 or or CC cord-001207-yjaiybwf 179 14 feeding feeding NN cord-001207-yjaiybwf 179 15 group group NN cord-001207-yjaiybwf 179 16 ( ( -LRB- cord-001207-yjaiybwf 179 17 Fig Fig NNP cord-001207-yjaiybwf 179 18 . . . cord-001207-yjaiybwf 179 19 6C 6C NNP cord-001207-yjaiybwf 179 20 ) ) -RRB- cord-001207-yjaiybwf 179 21 . . . cord-001207-yjaiybwf 180 1 Also also RB cord-001207-yjaiybwf 180 2 , , , cord-001207-yjaiybwf 180 3 no no DT cord-001207-yjaiybwf 180 4 grouping grouping NN cord-001207-yjaiybwf 180 5 according accord VBG cord-001207-yjaiybwf 180 6 to to IN cord-001207-yjaiybwf 180 7 age age NN cord-001207-yjaiybwf 180 8 or or CC cord-001207-yjaiybwf 180 9 feeding feeding NN cord-001207-yjaiybwf 180 10 group group NN cord-001207-yjaiybwf 180 11 was be VBD cord-001207-yjaiybwf 180 12 evident evident JJ cord-001207-yjaiybwf 180 13 , , , cord-001207-yjaiybwf 180 14 when when WRB cord-001207-yjaiybwf 180 15 only only RB cord-001207-yjaiybwf 180 16 the the DT cord-001207-yjaiybwf 180 17 sequences sequence NNS cord-001207-yjaiybwf 180 18 of of IN cord-001207-yjaiybwf 180 19 the the DT cord-001207-yjaiybwf 180 20 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 180 21 phages phage NNS cord-001207-yjaiybwf 180 22 were be VBD cord-001207-yjaiybwf 180 23 used use VBN cord-001207-yjaiybwf 180 24 for for IN cord-001207-yjaiybwf 180 25 the the DT cord-001207-yjaiybwf 180 26 analysis analysis NN cord-001207-yjaiybwf 180 27 ( ( -LRB- cord-001207-yjaiybwf 180 28 Fig Fig NNP cord-001207-yjaiybwf 180 29 . . . cord-001207-yjaiybwf 180 30 6D 6D NNP cord-001207-yjaiybwf 180 31 ) ) -RRB- cord-001207-yjaiybwf 180 32 . . . cord-001207-yjaiybwf 181 1 Comparisons comparison NNS cord-001207-yjaiybwf 181 2 of of IN cord-001207-yjaiybwf 181 3 the the DT cord-001207-yjaiybwf 181 4 composition composition NN cord-001207-yjaiybwf 181 5 of of IN cord-001207-yjaiybwf 181 6 intestinal intestinal JJ cord-001207-yjaiybwf 181 7 viromes virome NNS cord-001207-yjaiybwf 181 8 from from IN cord-001207-yjaiybwf 181 9 different different JJ cord-001207-yjaiybwf 181 10 samples sample NNS cord-001207-yjaiybwf 181 11 have have VBP cord-001207-yjaiybwf 181 12 been be VBN cord-001207-yjaiybwf 181 13 only only RB cord-001207-yjaiybwf 181 14 scarcely scarcely RB cord-001207-yjaiybwf 181 15 described describe VBN cord-001207-yjaiybwf 181 16 so so RB cord-001207-yjaiybwf 181 17 far far RB cord-001207-yjaiybwf 181 18 . . . cord-001207-yjaiybwf 182 1 A a DT cord-001207-yjaiybwf 182 2 few few JJ cord-001207-yjaiybwf 182 3 studies study NNS cord-001207-yjaiybwf 182 4 investigated investigate VBD cord-001207-yjaiybwf 182 5 individual individual JJ cord-001207-yjaiybwf 182 6 differences difference NNS cord-001207-yjaiybwf 182 7 of of IN cord-001207-yjaiybwf 182 8 faecal faecal JJ cord-001207-yjaiybwf 182 9 viromes virome NNS cord-001207-yjaiybwf 182 10 and and CC cord-001207-yjaiybwf 182 11 the the DT cord-001207-yjaiybwf 182 12 influence influence NN cord-001207-yjaiybwf 182 13 of of IN cord-001207-yjaiybwf 182 14 diet diet NN cord-001207-yjaiybwf 182 15 and and CC cord-001207-yjaiybwf 182 16 age age NN cord-001207-yjaiybwf 182 17 in in IN cord-001207-yjaiybwf 182 18 humans human NNS cord-001207-yjaiybwf 182 19 [ [ -LRB- cord-001207-yjaiybwf 182 20 1 1 CD cord-001207-yjaiybwf 182 21 , , , cord-001207-yjaiybwf 182 22 9 9 CD cord-001207-yjaiybwf 182 23 , , , cord-001207-yjaiybwf 182 24 24 24 CD cord-001207-yjaiybwf 182 25 ] ] -RRB- cord-001207-yjaiybwf 182 26 , , , cord-001207-yjaiybwf 182 27 whereas whereas IN cord-001207-yjaiybwf 182 28 similar similar JJ cord-001207-yjaiybwf 182 29 studies study NNS cord-001207-yjaiybwf 182 30 on on IN cord-001207-yjaiybwf 182 31 faecal faecal JJ cord-001207-yjaiybwf 182 32 viromes virome NNS cord-001207-yjaiybwf 182 33 of of IN cord-001207-yjaiybwf 182 34 pigs pig NNS cord-001207-yjaiybwf 182 35 are be VBP cord-001207-yjaiybwf 182 36 almost almost RB cord-001207-yjaiybwf 182 37 missing missing JJ cord-001207-yjaiybwf 182 38 . . . cord-001207-yjaiybwf 183 1 Technical technical JJ cord-001207-yjaiybwf 183 2 problems problem NNS cord-001207-yjaiybwf 183 3 with with IN cord-001207-yjaiybwf 183 4 the the DT cord-001207-yjaiybwf 183 5 use use NN cord-001207-yjaiybwf 183 6 of of IN cord-001207-yjaiybwf 183 7 deep deep JJ cord-001207-yjaiybwf 183 8 sequencing sequencing NN cord-001207-yjaiybwf 183 9 methods method NNS cord-001207-yjaiybwf 183 10 for for IN cord-001207-yjaiybwf 183 11 comparative comparative JJ cord-001207-yjaiybwf 183 12 virome virome NN cord-001207-yjaiybwf 183 13 analyses analysis NNS cord-001207-yjaiybwf 183 14 may may MD cord-001207-yjaiybwf 183 15 represent represent VB cord-001207-yjaiybwf 183 16 one one CD cord-001207-yjaiybwf 183 17 major major JJ cord-001207-yjaiybwf 183 18 problem problem NN cord-001207-yjaiybwf 183 19 in in IN cord-001207-yjaiybwf 183 20 this this DT cord-001207-yjaiybwf 183 21 context context NN cord-001207-yjaiybwf 183 22 [ [ -LRB- cord-001207-yjaiybwf 183 23 10 10 CD cord-001207-yjaiybwf 183 24 , , , cord-001207-yjaiybwf 183 25 48 48 CD cord-001207-yjaiybwf 183 26 ] ] -RRB- cord-001207-yjaiybwf 183 27 . . . cord-001207-yjaiybwf 184 1 Here here RB cord-001207-yjaiybwf 184 2 , , , cord-001207-yjaiybwf 184 3 we -PRON- PRP cord-001207-yjaiybwf 184 4 tried try VBD cord-001207-yjaiybwf 184 5 to to TO cord-001207-yjaiybwf 184 6 overcome overcome VB cord-001207-yjaiybwf 184 7 some some DT cord-001207-yjaiybwf 184 8 of of IN cord-001207-yjaiybwf 184 9 these these DT cord-001207-yjaiybwf 184 10 problems problem NNS cord-001207-yjaiybwf 184 11 by by IN cord-001207-yjaiybwf 184 12 using use VBG cord-001207-yjaiybwf 184 13 a a DT cord-001207-yjaiybwf 184 14 process process NN cord-001207-yjaiybwf 184 15 - - HYPH cord-001207-yjaiybwf 184 16 controlled control VBN cord-001207-yjaiybwf 184 17 deep deep JJ cord-001207-yjaiybwf 184 18 sequencing sequencing NN cord-001207-yjaiybwf 184 19 approach approach NN cord-001207-yjaiybwf 184 20 [ [ -LRB- cord-001207-yjaiybwf 184 21 10 10 CD cord-001207-yjaiybwf 184 22 ] ] -RRB- cord-001207-yjaiybwf 184 23 . . . cord-001207-yjaiybwf 185 1 By by IN cord-001207-yjaiybwf 185 2 this this DT cord-001207-yjaiybwf 185 3 , , , cord-001207-yjaiybwf 185 4 the the DT cord-001207-yjaiybwf 185 5 efficiency efficiency NN cord-001207-yjaiybwf 185 6 of of IN cord-001207-yjaiybwf 185 7 the the DT cord-001207-yjaiybwf 185 8 analysis analysis NN cord-001207-yjaiybwf 185 9 can can MD cord-001207-yjaiybwf 185 10 be be VB cord-001207-yjaiybwf 185 11 estimated estimate VBN cord-001207-yjaiybwf 185 12 for for IN cord-001207-yjaiybwf 185 13 each each DT cord-001207-yjaiybwf 185 14 sample sample NN cord-001207-yjaiybwf 185 15 , , , cord-001207-yjaiybwf 185 16 thereby thereby RB cord-001207-yjaiybwf 185 17 enabling enable VBG cord-001207-yjaiybwf 185 18 identification identification NN cord-001207-yjaiybwf 185 19 of of IN cord-001207-yjaiybwf 185 20 major major JJ cord-001207-yjaiybwf 185 21 differences difference NNS cord-001207-yjaiybwf 185 22 due due JJ cord-001207-yjaiybwf 185 23 to to IN cord-001207-yjaiybwf 185 24 different different JJ cord-001207-yjaiybwf 185 25 performances performance NNS cord-001207-yjaiybwf 185 26 of of IN cord-001207-yjaiybwf 185 27 the the DT cord-001207-yjaiybwf 185 28 method method NN cord-001207-yjaiybwf 185 29 . . . cord-001207-yjaiybwf 186 1 We -PRON- PRP cord-001207-yjaiybwf 186 2 could could MD cord-001207-yjaiybwf 186 3 show show VB cord-001207-yjaiybwf 186 4 here here RB cord-001207-yjaiybwf 186 5 , , , cord-001207-yjaiybwf 186 6 that that IN cord-001207-yjaiybwf 186 7 all all DT cord-001207-yjaiybwf 186 8 types type NNS cord-001207-yjaiybwf 186 9 of of IN cord-001207-yjaiybwf 186 10 the the DT cord-001207-yjaiybwf 186 11 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 186 12 used use VBN cord-001207-yjaiybwf 186 13 as as IN cord-001207-yjaiybwf 186 14 process process NN cord-001207-yjaiybwf 186 15 control control NN cord-001207-yjaiybwf 186 16 could could MD cord-001207-yjaiybwf 186 17 be be VB cord-001207-yjaiybwf 186 18 detected detect VBN cord-001207-yjaiybwf 186 19 in in IN cord-001207-yjaiybwf 186 20 the the DT cord-001207-yjaiybwf 186 21 final final JJ cord-001207-yjaiybwf 186 22 data data NN cord-001207-yjaiybwf 186 23 sets set NNS cord-001207-yjaiybwf 186 24 of of IN cord-001207-yjaiybwf 186 25 all all DT cord-001207-yjaiybwf 186 26 samples sample NNS cord-001207-yjaiybwf 186 27 . . . cord-001207-yjaiybwf 187 1 This this DT cord-001207-yjaiybwf 187 2 indicates indicate VBZ cord-001207-yjaiybwf 187 3 that that IN cord-001207-yjaiybwf 187 4 the the DT cord-001207-yjaiybwf 187 5 method method NN cord-001207-yjaiybwf 187 6 has have VBZ cord-001207-yjaiybwf 187 7 a a DT cord-001207-yjaiybwf 187 8 reproducible reproducible JJ cord-001207-yjaiybwf 187 9 performance performance NN cord-001207-yjaiybwf 187 10 and and CC cord-001207-yjaiybwf 187 11 the the DT cord-001207-yjaiybwf 187 12 generated generate VBN cord-001207-yjaiybwf 187 13 data datum NNS cord-001207-yjaiybwf 187 14 can can MD cord-001207-yjaiybwf 187 15 generally generally RB cord-001207-yjaiybwf 187 16 be be VB cord-001207-yjaiybwf 187 17 used use VBN cord-001207-yjaiybwf 187 18 for for IN cord-001207-yjaiybwf 187 19 comparative comparative JJ cord-001207-yjaiybwf 187 20 analyses analysis NNS cord-001207-yjaiybwf 187 21 . . . cord-001207-yjaiybwf 188 1 However however RB cord-001207-yjaiybwf 188 2 , , , cord-001207-yjaiybwf 188 3 the the DT cord-001207-yjaiybwf 188 4 detection detection NN cord-001207-yjaiybwf 188 5 rates rate NNS cord-001207-yjaiybwf 188 6 of of IN cord-001207-yjaiybwf 188 7 the the DT cord-001207-yjaiybwf 188 8 process process NN cord-001207-yjaiybwf 188 9 control control NN cord-001207-yjaiybwf 188 10 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 188 11 varied varied JJ cord-001207-yjaiybwf 188 12 between between IN cord-001207-yjaiybwf 188 13 the the DT cord-001207-yjaiybwf 188 14 samples sample NNS cord-001207-yjaiybwf 188 15 from from IN cord-001207-yjaiybwf 188 16 0.9 0.9 CD cord-001207-yjaiybwf 188 17 % % NN cord-001207-yjaiybwf 188 18 to to IN cord-001207-yjaiybwf 188 19 3.4 3.4 CD cord-001207-yjaiybwf 188 20 % % NN cord-001207-yjaiybwf 188 21 . . . cord-001207-yjaiybwf 189 1 As as IN cord-001207-yjaiybwf 189 2 the the DT cord-001207-yjaiybwf 189 3 detection detection NN cord-001207-yjaiybwf 189 4 rate rate NN cord-001207-yjaiybwf 189 5 of of IN cord-001207-yjaiybwf 189 6 the the DT cord-001207-yjaiybwf 189 7 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 189 8 is be VBZ cord-001207-yjaiybwf 189 9 -besides -besides : cord-001207-yjaiybwf 189 10 technical technical JJ cord-001207-yjaiybwf 189 11 factors factor NNS cord-001207-yjaiybwf 189 12 -also -also RB cord-001207-yjaiybwf 189 13 dependent dependent JJ cord-001207-yjaiybwf 189 14 on on IN cord-001207-yjaiybwf 189 15 the the DT cord-001207-yjaiybwf 189 16 amount amount NN cord-001207-yjaiybwf 189 17 of of IN cord-001207-yjaiybwf 189 18 viruses virus NNS cord-001207-yjaiybwf 189 19 initially initially RB cord-001207-yjaiybwf 189 20 present present JJ cord-001207-yjaiybwf 189 21 in in IN cord-001207-yjaiybwf 189 22 the the DT cord-001207-yjaiybwf 189 23 analyzed analyze VBN cord-001207-yjaiybwf 189 24 sample sample NN cord-001207-yjaiybwf 189 25 , , , cord-001207-yjaiybwf 189 26 improved improve VBN cord-001207-yjaiybwf 189 27 deep deep JJ cord-001207-yjaiybwf 189 28 sequencing sequencing NN cord-001207-yjaiybwf 189 29 methods method NNS cord-001207-yjaiybwf 189 30 enabling enable VBG cord-001207-yjaiybwf 189 31 quantitative quantitative JJ cord-001207-yjaiybwf 189 32 analyses analysis NNS cord-001207-yjaiybwf 189 33 should should MD cord-001207-yjaiybwf 189 34 be be VB cord-001207-yjaiybwf 189 35 developed develop VBN cord-001207-yjaiybwf 189 36 in in IN cord-001207-yjaiybwf 189 37 future future NN cord-001207-yjaiybwf 189 38 for for IN cord-001207-yjaiybwf 189 39 comparative comparative JJ cord-001207-yjaiybwf 189 40 virome virome NN cord-001207-yjaiybwf 189 41 investigations investigation NNS cord-001207-yjaiybwf 189 42 . . . cord-001207-yjaiybwf 190 1 In in IN cord-001207-yjaiybwf 190 2 the the DT cord-001207-yjaiybwf 190 3 eight eight CD cord-001207-yjaiybwf 190 4 investigated investigate VBN cord-001207-yjaiybwf 190 5 pooled pool VBN cord-001207-yjaiybwf 190 6 samples sample NNS cord-001207-yjaiybwf 190 7 , , , cord-001207-yjaiybwf 190 8 the the DT cord-001207-yjaiybwf 190 9 overall overall JJ cord-001207-yjaiybwf 190 10 composition composition NN cord-001207-yjaiybwf 190 11 of of IN cord-001207-yjaiybwf 190 12 the the DT cord-001207-yjaiybwf 190 13 virus virus NN cord-001207-yjaiybwf 190 14 community community NN cord-001207-yjaiybwf 190 15 was be VBD cord-001207-yjaiybwf 190 16 similar similar JJ cord-001207-yjaiybwf 190 17 to to IN cord-001207-yjaiybwf 190 18 that that DT cord-001207-yjaiybwf 190 19 described describe VBN cord-001207-yjaiybwf 190 20 for for IN cord-001207-yjaiybwf 190 21 other other JJ cord-001207-yjaiybwf 190 22 pig pig NN cord-001207-yjaiybwf 190 23 faecal faecal JJ cord-001207-yjaiybwf 190 24 viromes viromes NNP cord-001207-yjaiybwf 190 25 [ [ -LRB- cord-001207-yjaiybwf 190 26 2 2 CD cord-001207-yjaiybwf 190 27 , , , cord-001207-yjaiybwf 190 28 10 10 CD cord-001207-yjaiybwf 190 29 , , , cord-001207-yjaiybwf 190 30 11 11 CD cord-001207-yjaiybwf 190 31 ] ] -RRB- cord-001207-yjaiybwf 190 32 . . . cord-001207-yjaiybwf 191 1 The the DT cord-001207-yjaiybwf 191 2 two two CD cord-001207-yjaiybwf 191 3 major major JJ cord-001207-yjaiybwf 191 4 virus virus NN cord-001207-yjaiybwf 191 5 groups group NNS cord-001207-yjaiybwf 191 6 were be VBD cord-001207-yjaiybwf 191 7 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 191 8 and and CC cord-001207-yjaiybwf 191 9 porcine porcine JJ cord-001207-yjaiybwf 191 10 viruses virus NNS cord-001207-yjaiybwf 191 11 , , , cord-001207-yjaiybwf 191 12 whereas whereas IN cord-001207-yjaiybwf 191 13 plant plant NN cord-001207-yjaiybwf 191 14 viruses virus NNS cord-001207-yjaiybwf 191 15 and and CC cord-001207-yjaiybwf 191 16 viruses virus NNS cord-001207-yjaiybwf 191 17 with with IN cord-001207-yjaiybwf 191 18 other other JJ cord-001207-yjaiybwf 191 19 hosts host NNS cord-001207-yjaiybwf 191 20 were be VBD cord-001207-yjaiybwf 191 21 only only RB cord-001207-yjaiybwf 191 22 rarely rarely RB cord-001207-yjaiybwf 191 23 detected detect VBN cord-001207-yjaiybwf 191 24 . . . cord-001207-yjaiybwf 192 1 However however RB cord-001207-yjaiybwf 192 2 , , , cord-001207-yjaiybwf 192 3 large large JJ cord-001207-yjaiybwf 192 4 differences difference NNS cord-001207-yjaiybwf 192 5 were be VBD cord-001207-yjaiybwf 192 6 detected detect VBN cord-001207-yjaiybwf 192 7 in in IN cord-001207-yjaiybwf 192 8 the the DT cord-001207-yjaiybwf 192 9 ratio ratio NN cord-001207-yjaiybwf 192 10 between between IN cord-001207-yjaiybwf 192 11 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 192 12 and and CC cord-001207-yjaiybwf 192 13 mammalian mammalian JJ cord-001207-yjaiybwf 192 14 viruses virus NNS cord-001207-yjaiybwf 192 15 in in IN cord-001207-yjaiybwf 192 16 the the DT cord-001207-yjaiybwf 192 17 distinct distinct JJ cord-001207-yjaiybwf 192 18 samples sample NNS cord-001207-yjaiybwf 192 19 ; ; : cord-001207-yjaiybwf 192 20 in in IN cord-001207-yjaiybwf 192 21 addition addition NN cord-001207-yjaiybwf 192 22 , , , cord-001207-yjaiybwf 192 23 the the DT cord-001207-yjaiybwf 192 24 diversity diversity NN cord-001207-yjaiybwf 192 25 of of IN cord-001207-yjaiybwf 192 26 detected detect VBN cord-001207-yjaiybwf 192 27 virus virus NN cord-001207-yjaiybwf 192 28 species specie NNS cord-001207-yjaiybwf 192 29 varied varied JJ cord-001207-yjaiybwf 192 30 between between IN cord-001207-yjaiybwf 192 31 the the DT cord-001207-yjaiybwf 192 32 analysed analyse VBN cord-001207-yjaiybwf 192 33 viromes virome NNS cord-001207-yjaiybwf 192 34 . . . cord-001207-yjaiybwf 193 1 These these DT cord-001207-yjaiybwf 193 2 data datum NNS cord-001207-yjaiybwf 193 3 indicate indicate VBP cord-001207-yjaiybwf 193 4 that that IN cord-001207-yjaiybwf 193 5 the the DT cord-001207-yjaiybwf 193 6 faecal faecal JJ cord-001207-yjaiybwf 193 7 virome virome NN cord-001207-yjaiybwf 193 8 of of IN cord-001207-yjaiybwf 193 9 pigs pig NNS cord-001207-yjaiybwf 193 10 is be VBZ cord-001207-yjaiybwf 193 11 not not RB cord-001207-yjaiybwf 193 12 uniform uniform JJ cord-001207-yjaiybwf 193 13 and and CC cord-001207-yjaiybwf 193 14 static static JJ cord-001207-yjaiybwf 193 15 , , , cord-001207-yjaiybwf 193 16 but but CC cord-001207-yjaiybwf 193 17 shows show VBZ cord-001207-yjaiybwf 193 18 a a DT cord-001207-yjaiybwf 193 19 remarkable remarkable JJ cord-001207-yjaiybwf 193 20 variability variability NN cord-001207-yjaiybwf 193 21 . . . cord-001207-yjaiybwf 194 1 For for IN cord-001207-yjaiybwf 194 2 human human JJ cord-001207-yjaiybwf 194 3 faecal faecal JJ cord-001207-yjaiybwf 194 4 viromes virome NNS cord-001207-yjaiybwf 194 5 , , , cord-001207-yjaiybwf 194 6 a a DT cord-001207-yjaiybwf 194 7 high high JJ cord-001207-yjaiybwf 194 8 variability variability NN cord-001207-yjaiybwf 194 9 even even RB cord-001207-yjaiybwf 194 10 between between IN cord-001207-yjaiybwf 194 11 the the DT cord-001207-yjaiybwf 194 12 analyzed analyze VBN cord-001207-yjaiybwf 194 13 individuals individual NNS cord-001207-yjaiybwf 194 14 has have VBZ cord-001207-yjaiybwf 194 15 been be VBN cord-001207-yjaiybwf 194 16 described describe VBN cord-001207-yjaiybwf 194 17 [ [ -LRB- cord-001207-yjaiybwf 194 18 1 1 CD cord-001207-yjaiybwf 194 19 , , , cord-001207-yjaiybwf 194 20 9 9 CD cord-001207-yjaiybwf 194 21 ] ] -RRB- cord-001207-yjaiybwf 194 22 . . . cord-001207-yjaiybwf 195 1 As as IN cord-001207-yjaiybwf 195 2 only only RB cord-001207-yjaiybwf 195 3 pooled pool VBN cord-001207-yjaiybwf 195 4 faecal faecal JJ cord-001207-yjaiybwf 195 5 samples sample NNS cord-001207-yjaiybwf 195 6 have have VBP cord-001207-yjaiybwf 195 7 been be VBN cord-001207-yjaiybwf 195 8 analyzed analyze VBN cord-001207-yjaiybwf 195 9 in in IN cord-001207-yjaiybwf 195 10 the the DT cord-001207-yjaiybwf 195 11 study study NN cord-001207-yjaiybwf 195 12 presented present VBN cord-001207-yjaiybwf 195 13 here here RB cord-001207-yjaiybwf 195 14 , , , cord-001207-yjaiybwf 195 15 future future JJ cord-001207-yjaiybwf 195 16 investigations investigation NNS cord-001207-yjaiybwf 195 17 are be VBP cord-001207-yjaiybwf 195 18 necessary necessary JJ cord-001207-yjaiybwf 195 19 in in IN cord-001207-yjaiybwf 195 20 order order NN cord-001207-yjaiybwf 195 21 to to TO cord-001207-yjaiybwf 195 22 assess assess VB cord-001207-yjaiybwf 195 23 the the DT cord-001207-yjaiybwf 195 24 inter inter JJ cord-001207-yjaiybwf 195 25 - - JJ cord-001207-yjaiybwf 195 26 individual individual JJ cord-001207-yjaiybwf 195 27 variability variability NN cord-001207-yjaiybwf 195 28 of of IN cord-001207-yjaiybwf 195 29 faecal faecal JJ cord-001207-yjaiybwf 195 30 viromes virome NNS cord-001207-yjaiybwf 195 31 of of IN cord-001207-yjaiybwf 195 32 pigs pig NNS cord-001207-yjaiybwf 195 33 . . . cord-001207-yjaiybwf 196 1 The the DT cord-001207-yjaiybwf 196 2 most most RBS cord-001207-yjaiybwf 196 3 obvious obvious JJ cord-001207-yjaiybwf 196 4 factor factor NN cord-001207-yjaiybwf 196 5 influencing influence VBG cord-001207-yjaiybwf 196 6 the the DT cord-001207-yjaiybwf 196 7 composition composition NN cord-001207-yjaiybwf 196 8 of of IN cord-001207-yjaiybwf 196 9 the the DT cord-001207-yjaiybwf 196 10 pig pig NN cord-001207-yjaiybwf 196 11 faecal faecal JJ cord-001207-yjaiybwf 196 12 virome virome NNP cord-001207-yjaiybwf 196 13 was be VBD cord-001207-yjaiybwf 196 14 the the DT cord-001207-yjaiybwf 196 15 age age NN cord-001207-yjaiybwf 196 16 . . . cord-001207-yjaiybwf 197 1 The the DT cord-001207-yjaiybwf 197 2 percentage percentage NN cord-001207-yjaiybwf 197 3 of of IN cord-001207-yjaiybwf 197 4 porcine porcine JJ cord-001207-yjaiybwf 197 5 viruses virus NNS cord-001207-yjaiybwf 197 6 , , , cord-001207-yjaiybwf 197 7 which which WDT cord-001207-yjaiybwf 197 8 comprised comprise VBD cord-001207-yjaiybwf 197 9 the the DT cord-001207-yjaiybwf 197 10 most most RBS cord-001207-yjaiybwf 197 11 abundant abundant JJ cord-001207-yjaiybwf 197 12 group group NN cord-001207-yjaiybwf 197 13 in in IN cord-001207-yjaiybwf 197 14 the the DT cord-001207-yjaiybwf 197 15 youngest young JJS cord-001207-yjaiybwf 197 16 piglet piglet NN cord-001207-yjaiybwf 197 17 samples sample NNS cord-001207-yjaiybwf 197 18 , , , cord-001207-yjaiybwf 197 19 decreased decrease VBD cord-001207-yjaiybwf 197 20 dramatically dramatically RB cord-001207-yjaiybwf 197 21 in in IN cord-001207-yjaiybwf 197 22 the the DT cord-001207-yjaiybwf 197 23 samples sample NNS cord-001207-yjaiybwf 197 24 from from IN cord-001207-yjaiybwf 197 25 the the DT cord-001207-yjaiybwf 197 26 older old JJR cord-001207-yjaiybwf 197 27 pigs pig NNS cord-001207-yjaiybwf 197 28 . . . cord-001207-yjaiybwf 198 1 In in IN cord-001207-yjaiybwf 198 2 parallel parallel NN cord-001207-yjaiybwf 198 3 , , , cord-001207-yjaiybwf 198 4 the the DT cord-001207-yjaiybwf 198 5 percentage percentage NN cord-001207-yjaiybwf 198 6 of of IN cord-001207-yjaiybwf 198 7 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 198 8 as as RB cord-001207-yjaiybwf 198 9 well well RB cord-001207-yjaiybwf 198 10 as as IN cord-001207-yjaiybwf 198 11 the the DT cord-001207-yjaiybwf 198 12 diversity diversity NN cord-001207-yjaiybwf 198 13 of of IN cord-001207-yjaiybwf 198 14 detected detect VBN cord-001207-yjaiybwf 198 15 virus virus NN cord-001207-yjaiybwf 198 16 species specie NNS cord-001207-yjaiybwf 198 17 increased increase VBN cord-001207-yjaiybwf 198 18 by by IN cord-001207-yjaiybwf 198 19 age age NN cord-001207-yjaiybwf 198 20 . . . cord-001207-yjaiybwf 199 1 Interestingly interestingly RB cord-001207-yjaiybwf 199 2 , , , cord-001207-yjaiybwf 199 3 porcine porcine JJ cord-001207-yjaiybwf 199 4 kobuvirus kobuvirus NN cord-001207-yjaiybwf 199 5 and and CC cord-001207-yjaiybwf 199 6 pig pig NN cord-001207-yjaiybwf 199 7 SCV SCV NNP cord-001207-yjaiybwf 199 8 , , , cord-001207-yjaiybwf 199 9 which which WDT cord-001207-yjaiybwf 199 10 both both DT cord-001207-yjaiybwf 199 11 had have VBD cord-001207-yjaiybwf 199 12 been be VBN cord-001207-yjaiybwf 199 13 discovered discover VBN cord-001207-yjaiybwf 199 14 only only RB cord-001207-yjaiybwf 199 15 recently recently RB cord-001207-yjaiybwf 199 16 [ [ -LRB- cord-001207-yjaiybwf 199 17 10 10 CD cord-001207-yjaiybwf 199 18 , , , cord-001207-yjaiybwf 199 19 49 49 CD cord-001207-yjaiybwf 199 20 ] ] -RRB- cord-001207-yjaiybwf 199 21 , , , cord-001207-yjaiybwf 199 22 were be VBD cord-001207-yjaiybwf 199 23 among among IN cord-001207-yjaiybwf 199 24 the the DT cord-001207-yjaiybwf 199 25 most most RBS cord-001207-yjaiybwf 199 26 frequently frequently RB cord-001207-yjaiybwf 199 27 detected detect VBN cord-001207-yjaiybwf 199 28 viruses virus NNS cord-001207-yjaiybwf 199 29 in in IN cord-001207-yjaiybwf 199 30 the the DT cord-001207-yjaiybwf 199 31 faecal faecal JJ cord-001207-yjaiybwf 199 32 viromes virome NNS cord-001207-yjaiybwf 199 33 of of IN cord-001207-yjaiybwf 199 34 the the DT cord-001207-yjaiybwf 199 35 youngest young JJS cord-001207-yjaiybwf 199 36 and and CC cord-001207-yjaiybwf 199 37 oldest old JJS cord-001207-yjaiybwf 199 38 age age NN cord-001207-yjaiybwf 199 39 groups group NNS cord-001207-yjaiybwf 199 40 , , , cord-001207-yjaiybwf 199 41 respectively respectively RB cord-001207-yjaiybwf 199 42 . . . cord-001207-yjaiybwf 200 1 This this DT cord-001207-yjaiybwf 200 2 underlines underline VBZ cord-001207-yjaiybwf 200 3 the the DT cord-001207-yjaiybwf 200 4 importance importance NN cord-001207-yjaiybwf 200 5 of of IN cord-001207-yjaiybwf 200 6 unfocused unfocused JJ cord-001207-yjaiybwf 200 7 detection detection NN cord-001207-yjaiybwf 200 8 systems system NNS cord-001207-yjaiybwf 200 9 in in IN cord-001207-yjaiybwf 200 10 order order NN cord-001207-yjaiybwf 200 11 to to TO cord-001207-yjaiybwf 200 12 get get VB cord-001207-yjaiybwf 200 13 an an DT cord-001207-yjaiybwf 200 14 undistorted undistorted JJ cord-001207-yjaiybwf 200 15 picture picture NN cord-001207-yjaiybwf 200 16 of of IN cord-001207-yjaiybwf 200 17 the the DT cord-001207-yjaiybwf 200 18 abundance abundance NN cord-001207-yjaiybwf 200 19 of of IN cord-001207-yjaiybwf 200 20 viruses virus NNS cord-001207-yjaiybwf 200 21 in in IN cord-001207-yjaiybwf 200 22 a a DT cord-001207-yjaiybwf 200 23 sample sample NN cord-001207-yjaiybwf 200 24 . . . cord-001207-yjaiybwf 201 1 As as IN cord-001207-yjaiybwf 201 2 all all DT cord-001207-yjaiybwf 201 3 samples sample NNS cord-001207-yjaiybwf 201 4 analyzed analyze VBN cord-001207-yjaiybwf 201 5 here here RB cord-001207-yjaiybwf 201 6 originated originate VBD cord-001207-yjaiybwf 201 7 from from IN cord-001207-yjaiybwf 201 8 an an DT cord-001207-yjaiybwf 201 9 experimental experimental JJ cord-001207-yjaiybwf 201 10 feeding feeding NN cord-001207-yjaiybwf 201 11 trial trial NN cord-001207-yjaiybwf 201 12 , , , cord-001207-yjaiybwf 201 13 the the DT cord-001207-yjaiybwf 201 14 detected detect VBN cord-001207-yjaiybwf 201 15 virus virus NN cord-001207-yjaiybwf 201 16 composition composition NN cord-001207-yjaiybwf 201 17 may may MD cord-001207-yjaiybwf 201 18 vary vary VB cord-001207-yjaiybwf 201 19 in in IN cord-001207-yjaiybwf 201 20 comparison comparison NN cord-001207-yjaiybwf 201 21 to to IN cord-001207-yjaiybwf 201 22 field field NN cord-001207-yjaiybwf 201 23 - - HYPH cord-001207-yjaiybwf 201 24 origin origin NN cord-001207-yjaiybwf 201 25 samples sample NNS cord-001207-yjaiybwf 201 26 . . . cord-001207-yjaiybwf 202 1 However however RB cord-001207-yjaiybwf 202 2 , , , cord-001207-yjaiybwf 202 3 the the DT cord-001207-yjaiybwf 202 4 age age NN cord-001207-yjaiybwf 202 5 - - HYPH cord-001207-yjaiybwf 202 6 specific specific JJ cord-001207-yjaiybwf 202 7 effect effect NN cord-001207-yjaiybwf 202 8 was be VBD cord-001207-yjaiybwf 202 9 strong strong JJ cord-001207-yjaiybwf 202 10 and and CC cord-001207-yjaiybwf 202 11 very very RB cord-001207-yjaiybwf 202 12 similar similar JJ cord-001207-yjaiybwf 202 13 in in IN cord-001207-yjaiybwf 202 14 both both DT cord-001207-yjaiybwf 202 15 analyzed analyze VBN cord-001207-yjaiybwf 202 16 groups group NNS cord-001207-yjaiybwf 202 17 , , , cord-001207-yjaiybwf 202 18 which which WDT cord-001207-yjaiybwf 202 19 were be VBD cord-001207-yjaiybwf 202 20 held hold VBN cord-001207-yjaiybwf 202 21 completely completely RB cord-001207-yjaiybwf 202 22 separate separate JJ cord-001207-yjaiybwf 202 23 during during IN cord-001207-yjaiybwf 202 24 the the DT cord-001207-yjaiybwf 202 25 whole whole JJ cord-001207-yjaiybwf 202 26 period period NN cord-001207-yjaiybwf 202 27 of of IN cord-001207-yjaiybwf 202 28 the the DT cord-001207-yjaiybwf 202 29 experiment experiment NN cord-001207-yjaiybwf 202 30 . . . cord-001207-yjaiybwf 203 1 The the DT cord-001207-yjaiybwf 203 2 differences difference NNS cord-001207-yjaiybwf 203 3 may may MD cord-001207-yjaiybwf 203 4 be be VB cord-001207-yjaiybwf 203 5 explained explain VBN cord-001207-yjaiybwf 203 6 by by IN cord-001207-yjaiybwf 203 7 an an DT cord-001207-yjaiybwf 203 8 age age NN cord-001207-yjaiybwf 203 9 - - HYPH cord-001207-yjaiybwf 203 10 related relate VBN cord-001207-yjaiybwf 203 11 susceptibility susceptibility NN cord-001207-yjaiybwf 203 12 to to IN cord-001207-yjaiybwf 203 13 specific specific JJ cord-001207-yjaiybwf 203 14 virus virus NN cord-001207-yjaiybwf 203 15 infections infection NNS cord-001207-yjaiybwf 203 16 as as RB cord-001207-yjaiybwf 203 17 well well RB cord-001207-yjaiybwf 203 18 as as IN cord-001207-yjaiybwf 203 19 by by IN cord-001207-yjaiybwf 203 20 an an DT cord-001207-yjaiybwf 203 21 increasing increase VBG cord-001207-yjaiybwf 203 22 immunity immunity NN cord-001207-yjaiybwf 203 23 to to IN cord-001207-yjaiybwf 203 24 porcine porcine JJ cord-001207-yjaiybwf 203 25 viruses virus NNS cord-001207-yjaiybwf 203 26 due due JJ cord-001207-yjaiybwf 203 27 to to IN cord-001207-yjaiybwf 203 28 completed complete VBN cord-001207-yjaiybwf 203 29 virus virus NN cord-001207-yjaiybwf 203 30 infections infection NNS cord-001207-yjaiybwf 203 31 with with IN cord-001207-yjaiybwf 203 32 higher high JJR cord-001207-yjaiybwf 203 33 age age NN cord-001207-yjaiybwf 203 34 . . . cord-001207-yjaiybwf 204 1 In in IN cord-001207-yjaiybwf 204 2 addition addition NN cord-001207-yjaiybwf 204 3 , , , cord-001207-yjaiybwf 204 4 the the DT cord-001207-yjaiybwf 204 5 progressive progressive JJ cord-001207-yjaiybwf 204 6 diversification diversification NN cord-001207-yjaiybwf 204 7 of of IN cord-001207-yjaiybwf 204 8 the the DT cord-001207-yjaiybwf 204 9 bacterial bacterial JJ cord-001207-yjaiybwf 204 10 enteric enteric JJ cord-001207-yjaiybwf 204 11 flora flora NNS cord-001207-yjaiybwf 204 12 , , , cord-001207-yjaiybwf 204 13 which which WDT cord-001207-yjaiybwf 204 14 serves serve VBZ cord-001207-yjaiybwf 204 15 as as IN cord-001207-yjaiybwf 204 16 the the DT cord-001207-yjaiybwf 204 17 host host NN cord-001207-yjaiybwf 204 18 pool pool NN cord-001207-yjaiybwf 204 19 for for IN cord-001207-yjaiybwf 204 20 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 204 21 , , , cord-001207-yjaiybwf 204 22 would would MD cord-001207-yjaiybwf 204 23 also also RB cord-001207-yjaiybwf 204 24 explain explain VB cord-001207-yjaiybwf 204 25 the the DT cord-001207-yjaiybwf 204 26 increasing increase VBG cord-001207-yjaiybwf 204 27 diversification diversification NN cord-001207-yjaiybwf 204 28 of of IN cord-001207-yjaiybwf 204 29 the the DT cord-001207-yjaiybwf 204 30 virus virus NN cord-001207-yjaiybwf 204 31 flora flora NNS cord-001207-yjaiybwf 204 32 by by IN cord-001207-yjaiybwf 204 33 age age NN cord-001207-yjaiybwf 204 34 . . . cord-001207-yjaiybwf 205 1 An an DT cord-001207-yjaiybwf 205 2 increasing increase VBG cord-001207-yjaiybwf 205 3 diversity diversity NN cord-001207-yjaiybwf 205 4 of of IN cord-001207-yjaiybwf 205 5 the the DT cord-001207-yjaiybwf 205 6 virus virus NN cord-001207-yjaiybwf 205 7 species species NN cord-001207-yjaiybwf 205 8 in in IN cord-001207-yjaiybwf 205 9 faeces faece NNS cord-001207-yjaiybwf 205 10 of of IN cord-001207-yjaiybwf 205 11 humans human NNS cord-001207-yjaiybwf 205 12 has have VBZ cord-001207-yjaiybwf 205 13 already already RB cord-001207-yjaiybwf 205 14 been be VBN cord-001207-yjaiybwf 205 15 described describe VBN cord-001207-yjaiybwf 205 16 [ [ -LRB- cord-001207-yjaiybwf 205 17 24 24 CD cord-001207-yjaiybwf 205 18 ] ] -RRB- cord-001207-yjaiybwf 205 19 . . . cord-001207-yjaiybwf 206 1 In in IN cord-001207-yjaiybwf 206 2 contrast contrast NN cord-001207-yjaiybwf 206 3 to to IN cord-001207-yjaiybwf 206 4 the the DT cord-001207-yjaiybwf 206 5 age age NN cord-001207-yjaiybwf 206 6 - - HYPH cord-001207-yjaiybwf 206 7 related relate VBN cord-001207-yjaiybwf 206 8 effect effect NN cord-001207-yjaiybwf 206 9 , , , cord-001207-yjaiybwf 206 10 no no DT cord-001207-yjaiybwf 206 11 clear clear JJ cord-001207-yjaiybwf 206 12 differences difference NNS cord-001207-yjaiybwf 206 13 could could MD cord-001207-yjaiybwf 206 14 be be VB cord-001207-yjaiybwf 206 15 detected detect VBN cord-001207-yjaiybwf 206 16 in in IN cord-001207-yjaiybwf 206 17 the the DT cord-001207-yjaiybwf 206 18 composition composition NN cord-001207-yjaiybwf 206 19 of of IN cord-001207-yjaiybwf 206 20 the the DT cord-001207-yjaiybwf 206 21 faecal faecal JJ cord-001207-yjaiybwf 206 22 viromes virome NNS cord-001207-yjaiybwf 206 23 according accord VBG cord-001207-yjaiybwf 206 24 to to IN cord-001207-yjaiybwf 206 25 feeding feed VBG cord-001207-yjaiybwf 206 26 with with IN cord-001207-yjaiybwf 206 27 the the DT cord-001207-yjaiybwf 206 28 probiotic probiotic JJ cord-001207-yjaiybwf 206 29 bacterium bacterium NN cord-001207-yjaiybwf 206 30 E. E. NNP cord-001207-yjaiybwf 206 31 faecium faecium NN cord-001207-yjaiybwf 207 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 207 2 10415 10415 CD cord-001207-yjaiybwf 207 3 . . . cord-001207-yjaiybwf 208 1 A a DT cord-001207-yjaiybwf 208 2 relatively relatively RB cord-001207-yjaiybwf 208 3 high high JJ cord-001207-yjaiybwf 208 4 percentage percentage NN cord-001207-yjaiybwf 208 5 of of IN cord-001207-yjaiybwf 208 6 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 208 7 phages phage NNS cord-001207-yjaiybwf 208 8 in in IN cord-001207-yjaiybwf 208 9 the the DT cord-001207-yjaiybwf 208 10 sample sample NN cord-001207-yjaiybwf 208 11 derived derive VBN cord-001207-yjaiybwf 208 12 from from IN cord-001207-yjaiybwf 208 13 an an DT cord-001207-yjaiybwf 208 14 E. E. NNP cord-001207-yjaiybwf 208 15 faecium faecium NN cord-001207-yjaiybwf 208 16 - - HYPH cord-001207-yjaiybwf 208 17 feeded feed VBN cord-001207-yjaiybwf 208 18 group group NN cord-001207-yjaiybwf 208 19 may may MD cord-001207-yjaiybwf 208 20 indicate indicate VB cord-001207-yjaiybwf 208 21 multiplication multiplication NN cord-001207-yjaiybwf 208 22 of of IN cord-001207-yjaiybwf 208 23 the the DT cord-001207-yjaiybwf 208 24 phage phage NN cord-001207-yjaiybwf 208 25 due due IN cord-001207-yjaiybwf 208 26 to to IN cord-001207-yjaiybwf 208 27 the the DT cord-001207-yjaiybwf 208 28 application application NN cord-001207-yjaiybwf 208 29 of of IN cord-001207-yjaiybwf 208 30 its -PRON- PRP$ cord-001207-yjaiybwf 208 31 host host NN cord-001207-yjaiybwf 208 32 . . . cord-001207-yjaiybwf 209 1 This this DT cord-001207-yjaiybwf 209 2 explanation explanation NN cord-001207-yjaiybwf 209 3 may may MD cord-001207-yjaiybwf 209 4 indicate indicate VB cord-001207-yjaiybwf 209 5 that that IN cord-001207-yjaiybwf 209 6 a a DT cord-001207-yjaiybwf 209 7 larger large JJR cord-001207-yjaiybwf 209 8 amount amount NN cord-001207-yjaiybwf 209 9 of of IN cord-001207-yjaiybwf 209 10 the the DT cord-001207-yjaiybwf 209 11 probiotic probiotic JJ cord-001207-yjaiybwf 209 12 bacteria bacteria NNS cord-001207-yjaiybwf 209 13 may may MD cord-001207-yjaiybwf 209 14 be be VB cord-001207-yjaiybwf 209 15 lysed lyse VBN cord-001207-yjaiybwf 209 16 by by IN cord-001207-yjaiybwf 209 17 the the DT cord-001207-yjaiybwf 209 18 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 209 19 and and CC cord-001207-yjaiybwf 209 20 are be VBP cord-001207-yjaiybwf 209 21 therefore therefore RB cord-001207-yjaiybwf 209 22 not not RB cord-001207-yjaiybwf 209 23 available available JJ cord-001207-yjaiybwf 209 24 for for IN cord-001207-yjaiybwf 209 25 the the DT cord-001207-yjaiybwf 209 26 probiotic probiotic JJ cord-001207-yjaiybwf 209 27 therapy therapy NN cord-001207-yjaiybwf 209 28 ; ; : cord-001207-yjaiybwf 209 29 however however RB cord-001207-yjaiybwf 209 30 , , , cord-001207-yjaiybwf 209 31 this this DT cord-001207-yjaiybwf 209 32 interpretation interpretation NN cord-001207-yjaiybwf 209 33 is be VBZ cord-001207-yjaiybwf 209 34 questionable questionable JJ cord-001207-yjaiybwf 209 35 as as IN cord-001207-yjaiybwf 209 36 the the DT cord-001207-yjaiybwf 209 37 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 209 38 were be VBD cord-001207-yjaiybwf 209 39 only only RB cord-001207-yjaiybwf 209 40 found find VBN cord-001207-yjaiybwf 209 41 in in IN cord-001207-yjaiybwf 209 42 one one CD cord-001207-yjaiybwf 209 43 of of IN cord-001207-yjaiybwf 209 44 the the DT cord-001207-yjaiybwf 209 45 samples sample NNS cord-001207-yjaiybwf 209 46 . . . cord-001207-yjaiybwf 210 1 Also also RB cord-001207-yjaiybwf 210 2 , , , cord-001207-yjaiybwf 210 3 a a DT cord-001207-yjaiybwf 210 4 relative relative JJ cord-001207-yjaiybwf 210 5 high high JJ cord-001207-yjaiybwf 210 6 proportion proportion NN cord-001207-yjaiybwf 210 7 of of IN cord-001207-yjaiybwf 210 8 astrovirus astrovirus NNP cord-001207-yjaiybwf 210 9 was be VBD cord-001207-yjaiybwf 210 10 found find VBN cord-001207-yjaiybwf 210 11 in in IN cord-001207-yjaiybwf 210 12 one one CD cord-001207-yjaiybwf 210 13 of of IN cord-001207-yjaiybwf 210 14 the the DT cord-001207-yjaiybwf 210 15 samples sample NNS cord-001207-yjaiybwf 210 16 of of IN cord-001207-yjaiybwf 210 17 the the DT cord-001207-yjaiybwf 210 18 control control NN cord-001207-yjaiybwf 210 19 group group NN cord-001207-yjaiybwf 210 20 . . . cord-001207-yjaiybwf 211 1 Interestingly interestingly RB cord-001207-yjaiybwf 211 2 , , , cord-001207-yjaiybwf 211 3 real real JJ cord-001207-yjaiybwf 211 4 - - HYPH cord-001207-yjaiybwf 211 5 time time NN cord-001207-yjaiybwf 211 6 RT rt NN cord-001207-yjaiybwf 211 7 - - HYPH cord-001207-yjaiybwf 211 8 PCR PCR NNP cord-001207-yjaiybwf 211 9 analyses analysis NNS cord-001207-yjaiybwf 211 10 of of IN cord-001207-yjaiybwf 211 11 samples sample NNS cord-001207-yjaiybwf 211 12 derived derive VBN cord-001207-yjaiybwf 211 13 from from IN cord-001207-yjaiybwf 211 14 the the DT cord-001207-yjaiybwf 211 15 same same JJ cord-001207-yjaiybwf 211 16 feeding feeding NN cord-001207-yjaiybwf 211 17 trial trial NN cord-001207-yjaiybwf 211 18 confirmed confirm VBD cord-001207-yjaiybwf 211 19 the the DT cord-001207-yjaiybwf 211 20 presence presence NN cord-001207-yjaiybwf 211 21 of of IN cord-001207-yjaiybwf 211 22 astrovirus astrovirus NNP cord-001207-yjaiybwf 211 23 exclusively exclusively RB cord-001207-yjaiybwf 211 24 in in IN cord-001207-yjaiybwf 211 25 the the DT cord-001207-yjaiybwf 211 26 control control NN cord-001207-yjaiybwf 211 27 group group NN cord-001207-yjaiybwf 211 28 [ [ -LRB- cord-001207-yjaiybwf 211 29 30 30 CD cord-001207-yjaiybwf 211 30 ] ] -RRB- cord-001207-yjaiybwf 211 31 . . . cord-001207-yjaiybwf 212 1 However however RB cord-001207-yjaiybwf 212 2 , , , cord-001207-yjaiybwf 212 3 the the DT cord-001207-yjaiybwf 212 4 same same JJ cord-001207-yjaiybwf 212 5 study study NN cord-001207-yjaiybwf 212 6 indicated indicate VBD cord-001207-yjaiybwf 212 7 later later RB cord-001207-yjaiybwf 212 8 shedding shed VBG cord-001207-yjaiybwf 212 9 of of IN cord-001207-yjaiybwf 212 10 rotaviruses rotavirus NNS cord-001207-yjaiybwf 212 11 with with IN cord-001207-yjaiybwf 212 12 lower low JJR cord-001207-yjaiybwf 212 13 amounts amount NNS cord-001207-yjaiybwf 212 14 in in IN cord-001207-yjaiybwf 212 15 the the DT cord-001207-yjaiybwf 212 16 probiotic probiotic JJ cord-001207-yjaiybwf 212 17 group group NN cord-001207-yjaiybwf 212 18 as as IN cord-001207-yjaiybwf 212 19 compared compare VBN cord-001207-yjaiybwf 212 20 to to IN cord-001207-yjaiybwf 212 21 the the DT cord-001207-yjaiybwf 212 22 control control NN cord-001207-yjaiybwf 212 23 group group NN cord-001207-yjaiybwf 212 24 , , , cord-001207-yjaiybwf 212 25 which which WDT cord-001207-yjaiybwf 212 26 was be VBD cord-001207-yjaiybwf 212 27 not not RB cord-001207-yjaiybwf 212 28 detected detect VBN cord-001207-yjaiybwf 212 29 by by IN cord-001207-yjaiybwf 212 30 our -PRON- PRP$ cord-001207-yjaiybwf 212 31 virome virome NN cord-001207-yjaiybwf 212 32 analysis analysis NN cord-001207-yjaiybwf 212 33 . . . cord-001207-yjaiybwf 213 1 A a DT cord-001207-yjaiybwf 213 2 closer close JJR cord-001207-yjaiybwf 213 3 inspection inspection NN cord-001207-yjaiybwf 213 4 of of IN cord-001207-yjaiybwf 213 5 the the DT cord-001207-yjaiybwf 213 6 data datum NNS cord-001207-yjaiybwf 213 7 shows show VBZ cord-001207-yjaiybwf 213 8 that that IN cord-001207-yjaiybwf 213 9 up up IN cord-001207-yjaiybwf 213 10 to to TO cord-001207-yjaiybwf 213 11 10 10 CD cord-001207-yjaiybwf 213 12 7 7 CD cord-001207-yjaiybwf 213 13 astroviruses astroviruse NNS cord-001207-yjaiybwf 213 14 per per IN cord-001207-yjaiybwf 213 15 gram gram NN cord-001207-yjaiybwf 213 16 faeces faece NNS cord-001207-yjaiybwf 213 17 were be VBD cord-001207-yjaiybwf 213 18 present present JJ cord-001207-yjaiybwf 213 19 in in IN cord-001207-yjaiybwf 213 20 the the DT cord-001207-yjaiybwf 213 21 samples sample NNS cord-001207-yjaiybwf 213 22 , , , cord-001207-yjaiybwf 213 23 whereas whereas IN cord-001207-yjaiybwf 213 24 only only RB cord-001207-yjaiybwf 213 25 up up IN cord-001207-yjaiybwf 213 26 to to TO cord-001207-yjaiybwf 213 27 10 10 CD cord-001207-yjaiybwf 213 28 5 5 CD cord-001207-yjaiybwf 213 29 rotaviruses rotavirus NNS cord-001207-yjaiybwf 213 30 per per IN cord-001207-yjaiybwf 213 31 gram gram NN cord-001207-yjaiybwf 213 32 were be VBD cord-001207-yjaiybwf 213 33 detected detect VBN cord-001207-yjaiybwf 213 34 [ [ -LRB- cord-001207-yjaiybwf 213 35 30 30 CD cord-001207-yjaiybwf 213 36 ] ] -RRB- cord-001207-yjaiybwf 213 37 . . . cord-001207-yjaiybwf 214 1 Therefore therefore RB cord-001207-yjaiybwf 214 2 , , , cord-001207-yjaiybwf 214 3 a a DT cord-001207-yjaiybwf 214 4 lower low JJR cord-001207-yjaiybwf 214 5 sensitivity sensitivity NN cord-001207-yjaiybwf 214 6 of of IN cord-001207-yjaiybwf 214 7 the the DT cord-001207-yjaiybwf 214 8 virome virome NNP cord-001207-yjaiybwf 214 9 analysis analysis NN cord-001207-yjaiybwf 214 10 method method NN cord-001207-yjaiybwf 214 11 may may MD cord-001207-yjaiybwf 214 12 explain explain VB cord-001207-yjaiybwf 214 13 the the DT cord-001207-yjaiybwf 214 14 discrepancies discrepancy NNS cord-001207-yjaiybwf 214 15 and and CC cord-001207-yjaiybwf 214 16 still still RB cord-001207-yjaiybwf 214 17 deeper deep JJR cord-001207-yjaiybwf 214 18 sequencings sequencing NNS cord-001207-yjaiybwf 214 19 may may MD cord-001207-yjaiybwf 214 20 be be VB cord-001207-yjaiybwf 214 21 necessary necessary JJ cord-001207-yjaiybwf 214 22 in in IN cord-001207-yjaiybwf 214 23 future future NN cord-001207-yjaiybwf 214 24 to to TO cord-001207-yjaiybwf 214 25 detect detect VB cord-001207-yjaiybwf 214 26 more more RBR cord-001207-yjaiybwf 214 27 subtle subtle JJ cord-001207-yjaiybwf 214 28 changes change NNS cord-001207-yjaiybwf 214 29 in in IN cord-001207-yjaiybwf 214 30 the the DT cord-001207-yjaiybwf 214 31 faecal faecal JJ cord-001207-yjaiybwf 214 32 virome virome NN cord-001207-yjaiybwf 214 33 composition composition NN cord-001207-yjaiybwf 214 34 due due IN cord-001207-yjaiybwf 214 35 to to IN cord-001207-yjaiybwf 214 36 probiotic probiotic JJ cord-001207-yjaiybwf 214 37 feeding feeding NN cord-001207-yjaiybwf 214 38 . . . cord-001207-yjaiybwf 215 1 The the DT cord-001207-yjaiybwf 215 2 composition composition NN cord-001207-yjaiybwf 215 3 of of IN cord-001207-yjaiybwf 215 4 the the DT cord-001207-yjaiybwf 215 5 identified identify VBN cord-001207-yjaiybwf 215 6 bacteriophage bacteriophage NN cord-001207-yjaiybwf 215 7 species specie NNS cord-001207-yjaiybwf 215 8 in in IN cord-001207-yjaiybwf 215 9 the the DT cord-001207-yjaiybwf 215 10 different different JJ cord-001207-yjaiybwf 215 11 samples sample NNS cord-001207-yjaiybwf 215 12 revealed reveal VBD cord-001207-yjaiybwf 215 13 no no DT cord-001207-yjaiybwf 215 14 consistent consistent JJ cord-001207-yjaiybwf 215 15 pattern pattern NN cord-001207-yjaiybwf 215 16 . . . cord-001207-yjaiybwf 216 1 However however RB cord-001207-yjaiybwf 216 2 , , , cord-001207-yjaiybwf 216 3 most most JJS cord-001207-yjaiybwf 216 4 of of IN cord-001207-yjaiybwf 216 5 the the DT cord-001207-yjaiybwf 216 6 detected detect VBN cord-001207-yjaiybwf 216 7 sequence sequence NN cord-001207-yjaiybwf 216 8 reads read NNS cord-001207-yjaiybwf 216 9 showed show VBD cord-001207-yjaiybwf 216 10 only only RB cord-001207-yjaiybwf 216 11 moderate moderate JJ cord-001207-yjaiybwf 216 12 identities identity NNS cord-001207-yjaiybwf 216 13 to to IN cord-001207-yjaiybwf 216 14 the the DT cord-001207-yjaiybwf 216 15 known know VBN cord-001207-yjaiybwf 216 16 bacteriophage bacteriophage NN cord-001207-yjaiybwf 216 17 sequences sequence NNS cord-001207-yjaiybwf 216 18 present present JJ cord-001207-yjaiybwf 216 19 in in IN cord-001207-yjaiybwf 216 20 the the DT cord-001207-yjaiybwf 216 21 database database NN cord-001207-yjaiybwf 216 22 . . . cord-001207-yjaiybwf 217 1 Therefore therefore RB cord-001207-yjaiybwf 217 2 , , , cord-001207-yjaiybwf 217 3 it -PRON- PRP cord-001207-yjaiybwf 217 4 has have VBZ cord-001207-yjaiybwf 217 5 to to TO cord-001207-yjaiybwf 217 6 be be VB cord-001207-yjaiybwf 217 7 considered consider VBN cord-001207-yjaiybwf 217 8 that that IN cord-001207-yjaiybwf 217 9 the the DT cord-001207-yjaiybwf 217 10 majority majority NN cord-001207-yjaiybwf 217 11 of of IN cord-001207-yjaiybwf 217 12 the the DT cord-001207-yjaiybwf 217 13 detected detect VBN cord-001207-yjaiybwf 217 14 sequences sequence NNS cord-001207-yjaiybwf 217 15 belong belong VBP cord-001207-yjaiybwf 217 16 to to IN cord-001207-yjaiybwf 217 17 so so RB cord-001207-yjaiybwf 217 18 far far RB cord-001207-yjaiybwf 217 19 unknown unknown JJ cord-001207-yjaiybwf 217 20 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 217 21 and and CC cord-001207-yjaiybwf 217 22 that that IN cord-001207-yjaiybwf 217 23 the the DT cord-001207-yjaiybwf 217 24 identified identify VBN cord-001207-yjaiybwf 217 25 bacteriophage bacteriophage NN cord-001207-yjaiybwf 217 26 species specie NNS cord-001207-yjaiybwf 217 27 represent represent VBP cord-001207-yjaiybwf 217 28 only only RB cord-001207-yjaiybwf 217 29 their -PRON- PRP$ cord-001207-yjaiybwf 217 30 next next JJ cord-001207-yjaiybwf 217 31 relatives relative NNS cord-001207-yjaiybwf 217 32 . . . cord-001207-yjaiybwf 218 1 A a DT cord-001207-yjaiybwf 218 2 definitive definitive JJ cord-001207-yjaiybwf 218 3 assignment assignment NN cord-001207-yjaiybwf 218 4 of of IN cord-001207-yjaiybwf 218 5 a a DT cord-001207-yjaiybwf 218 6 host host NN cord-001207-yjaiybwf 218 7 to to IN cord-001207-yjaiybwf 218 8 these these DT cord-001207-yjaiybwf 218 9 sequences sequence NNS cord-001207-yjaiybwf 218 10 is be VBZ cord-001207-yjaiybwf 218 11 therefore therefore RB cord-001207-yjaiybwf 218 12 currently currently RB cord-001207-yjaiybwf 218 13 not not RB cord-001207-yjaiybwf 218 14 possible possible JJ cord-001207-yjaiybwf 218 15 . . . cord-001207-yjaiybwf 219 1 The the DT cord-001207-yjaiybwf 219 2 quality quality NN cord-001207-yjaiybwf 219 3 of of IN cord-001207-yjaiybwf 219 4 the the DT cord-001207-yjaiybwf 219 5 database database NN cord-001207-yjaiybwf 219 6 with with IN cord-001207-yjaiybwf 219 7 regard regard NN cord-001207-yjaiybwf 219 8 to to IN cord-001207-yjaiybwf 219 9 genomic genomic JJ cord-001207-yjaiybwf 219 10 sequences sequence NNS cord-001207-yjaiybwf 219 11 of of IN cord-001207-yjaiybwf 219 12 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 219 13 is be VBZ cord-001207-yjaiybwf 219 14 crucial crucial JJ cord-001207-yjaiybwf 219 15 for for IN cord-001207-yjaiybwf 219 16 virome virome NN cord-001207-yjaiybwf 219 17 analyses analysis NNS cord-001207-yjaiybwf 219 18 . . . cord-001207-yjaiybwf 220 1 For for IN cord-001207-yjaiybwf 220 2 example example NN cord-001207-yjaiybwf 220 3 , , , cord-001207-yjaiybwf 220 4 the the DT cord-001207-yjaiybwf 220 5 high high JJ cord-001207-yjaiybwf 220 6 proportion proportion NN cord-001207-yjaiybwf 220 7 of of IN cord-001207-yjaiybwf 220 8 the the DT cord-001207-yjaiybwf 220 9 detected detect VBN cord-001207-yjaiybwf 220 10 Lactococcus Lactococcus NNP cord-001207-yjaiybwf 220 11 phage phage NN cord-001207-yjaiybwf 220 12 1706 1706 CD cord-001207-yjaiybwf 220 13 may may MD cord-001207-yjaiybwf 220 14 reflect reflect VB cord-001207-yjaiybwf 220 15 the the DT cord-001207-yjaiybwf 220 16 disproportionately disproportionately RB cord-001207-yjaiybwf 220 17 high high JJ cord-001207-yjaiybwf 220 18 abundance abundance NN cord-001207-yjaiybwf 220 19 of of IN cord-001207-yjaiybwf 220 20 those those DT cord-001207-yjaiybwf 220 21 phage phage NN cord-001207-yjaiybwf 220 22 sequences sequence NNS cord-001207-yjaiybwf 220 23 in in IN cord-001207-yjaiybwf 220 24 the the DT cord-001207-yjaiybwf 220 25 database database NN cord-001207-yjaiybwf 220 26 as as IN cord-001207-yjaiybwf 220 27 a a DT cord-001207-yjaiybwf 220 28 consequence consequence NN cord-001207-yjaiybwf 220 29 of of IN cord-001207-yjaiybwf 220 30 intensive intensive JJ cord-001207-yjaiybwf 220 31 research research NN cord-001207-yjaiybwf 220 32 on on IN cord-001207-yjaiybwf 220 33 these these DT cord-001207-yjaiybwf 220 34 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 220 35 , , , cord-001207-yjaiybwf 220 36 which which WDT cord-001207-yjaiybwf 220 37 are be VBP cord-001207-yjaiybwf 220 38 problematic problematic JJ cord-001207-yjaiybwf 220 39 agents agent NNS cord-001207-yjaiybwf 220 40 for for IN cord-001207-yjaiybwf 220 41 the the DT cord-001207-yjaiybwf 220 42 diary diary NN cord-001207-yjaiybwf 220 43 cheese cheese NN cord-001207-yjaiybwf 220 44 product product NN cord-001207-yjaiybwf 220 45 industry industry NN cord-001207-yjaiybwf 220 46 [ [ -LRB- cord-001207-yjaiybwf 220 47 50 50 CD cord-001207-yjaiybwf 220 48 ] ] -RRB- cord-001207-yjaiybwf 220 49 . . . cord-001207-yjaiybwf 221 1 In in IN cord-001207-yjaiybwf 221 2 contrast contrast NN cord-001207-yjaiybwf 221 3 , , , cord-001207-yjaiybwf 221 4 for for IN cord-001207-yjaiybwf 221 5 another another DT cord-001207-yjaiybwf 221 6 highly highly RB cord-001207-yjaiybwf 221 7 abundant abundant JJ cord-001207-yjaiybwf 221 8 bacteriophage bacteriophage NN cord-001207-yjaiybwf 221 9 , , , cord-001207-yjaiybwf 221 10 the the DT cord-001207-yjaiybwf 221 11 dragonfly dragonfly NN cord-001207-yjaiybwf 221 12 - - HYPH cord-001207-yjaiybwf 221 13 associated associate VBN cord-001207-yjaiybwf 221 14 microphage microphage NN cord-001207-yjaiybwf 221 15 , , , cord-001207-yjaiybwf 221 16 the the DT cord-001207-yjaiybwf 221 17 specific specific JJ cord-001207-yjaiybwf 221 18 bacterial bacterial JJ cord-001207-yjaiybwf 221 19 host host NN cord-001207-yjaiybwf 221 20 is be VBZ cord-001207-yjaiybwf 221 21 still still RB cord-001207-yjaiybwf 221 22 unknown unknown JJ cord-001207-yjaiybwf 221 23 [ [ -LRB- cord-001207-yjaiybwf 221 24 51 51 CD cord-001207-yjaiybwf 221 25 ] ] -RRB- cord-001207-yjaiybwf 221 26 . . . cord-001207-yjaiybwf 222 1 An an DT cord-001207-yjaiybwf 222 2 increase increase NN cord-001207-yjaiybwf 222 3 of of IN cord-001207-yjaiybwf 222 4 annotated annotate VBN cord-001207-yjaiybwf 222 5 bacteriophage bacteriophage NN cord-001207-yjaiybwf 222 6 sequences sequence NNS cord-001207-yjaiybwf 222 7 in in IN cord-001207-yjaiybwf 222 8 the the DT cord-001207-yjaiybwf 222 9 databases database NNS cord-001207-yjaiybwf 222 10 is be VBZ cord-001207-yjaiybwf 222 11 therefore therefore RB cord-001207-yjaiybwf 222 12 a a DT cord-001207-yjaiybwf 222 13 prerequisite prerequisite NN cord-001207-yjaiybwf 222 14 for for IN cord-001207-yjaiybwf 222 15 studies study NNS cord-001207-yjaiybwf 222 16 on on IN cord-001207-yjaiybwf 222 17 the the DT cord-001207-yjaiybwf 222 18 interactions interaction NNS cord-001207-yjaiybwf 222 19 between between IN cord-001207-yjaiybwf 222 20 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 222 21 and and CC cord-001207-yjaiybwf 222 22 their -PRON- PRP$ cord-001207-yjaiybwf 222 23 host host NN cord-001207-yjaiybwf 222 24 bacteria bacteria NNS cord-001207-yjaiybwf 222 25 in in IN cord-001207-yjaiybwf 222 26 the the DT cord-001207-yjaiybwf 222 27 gut gut NN cord-001207-yjaiybwf 222 28 in in IN cord-001207-yjaiybwf 222 29 future future NN cord-001207-yjaiybwf 222 30 . . . cord-001207-yjaiybwf 223 1 Alternatively alternatively RB cord-001207-yjaiybwf 223 2 , , , cord-001207-yjaiybwf 223 3 a a DT cord-001207-yjaiybwf 223 4 deeper deep JJR cord-001207-yjaiybwf 223 5 sequencing sequencing NN cord-001207-yjaiybwf 223 6 may may MD cord-001207-yjaiybwf 223 7 enable enable VB cord-001207-yjaiybwf 223 8 the the DT cord-001207-yjaiybwf 223 9 assembly assembly NN cord-001207-yjaiybwf 223 10 of of IN cord-001207-yjaiybwf 223 11 complete complete JJ cord-001207-yjaiybwf 223 12 bacteriophage bacteriophage NN cord-001207-yjaiybwf 223 13 genome genome NN cord-001207-yjaiybwf 223 14 sequences sequence NNS cord-001207-yjaiybwf 223 15 from from IN cord-001207-yjaiybwf 223 16 the the DT cord-001207-yjaiybwf 223 17 metagenomic metagenomic NNP cord-001207-yjaiybwf 223 18 data data NNP cord-001207-yjaiybwf 223 19 set set NN cord-001207-yjaiybwf 223 20 . . . cord-001207-yjaiybwf 224 1 By by IN cord-001207-yjaiybwf 224 2 this this DT cord-001207-yjaiybwf 224 3 , , , cord-001207-yjaiybwf 224 4 an an DT cord-001207-yjaiybwf 224 5 assignment assignment NN cord-001207-yjaiybwf 224 6 to to IN cord-001207-yjaiybwf 224 7 their -PRON- PRP$ cord-001207-yjaiybwf 224 8 hosts host NNS cord-001207-yjaiybwf 224 9 was be VBD cord-001207-yjaiybwf 224 10 possible possible JJ cord-001207-yjaiybwf 224 11 by by IN cord-001207-yjaiybwf 224 12 identification identification NN cord-001207-yjaiybwf 224 13 of of IN cord-001207-yjaiybwf 224 14 inserted insert VBN cord-001207-yjaiybwf 224 15 host host NN cord-001207-yjaiybwf 224 16 - - HYPH cord-001207-yjaiybwf 224 17 related relate VBN cord-001207-yjaiybwf 224 18 sequences sequence NNS cord-001207-yjaiybwf 224 19 as as IN cord-001207-yjaiybwf 224 20 recently recently RB cord-001207-yjaiybwf 224 21 described describe VBD cord-001207-yjaiybwf 224 22 [ [ -LRB- cord-001207-yjaiybwf 224 23 3 3 CD cord-001207-yjaiybwf 224 24 ] ] -RRB- cord-001207-yjaiybwf 224 25 . . . cord-001207-yjaiybwf 225 1 In in IN cord-001207-yjaiybwf 225 2 summary summary NN cord-001207-yjaiybwf 225 3 the the DT cord-001207-yjaiybwf 225 4 data datum NNS cord-001207-yjaiybwf 225 5 show show VBP cord-001207-yjaiybwf 225 6 a a DT cord-001207-yjaiybwf 225 7 high high JJ cord-001207-yjaiybwf 225 8 variability variability NN cord-001207-yjaiybwf 225 9 of of IN cord-001207-yjaiybwf 225 10 the the DT cord-001207-yjaiybwf 225 11 pig pig NN cord-001207-yjaiybwf 225 12 faecal faecal JJ cord-001207-yjaiybwf 225 13 virome virome NNP cord-001207-yjaiybwf 225 14 . . . cord-001207-yjaiybwf 226 1 Most most RBS cord-001207-yjaiybwf 226 2 obvious obvious JJ cord-001207-yjaiybwf 226 3 are be VBP cord-001207-yjaiybwf 226 4 age age NN cord-001207-yjaiybwf 226 5 - - HYPH cord-001207-yjaiybwf 226 6 related relate VBN cord-001207-yjaiybwf 226 7 differences difference NNS cord-001207-yjaiybwf 226 8 in in IN cord-001207-yjaiybwf 226 9 the the DT cord-001207-yjaiybwf 226 10 proportion proportion NN cord-001207-yjaiybwf 226 11 between between IN cord-001207-yjaiybwf 226 12 pig pig NN cord-001207-yjaiybwf 226 13 viruses virus NNS cord-001207-yjaiybwf 226 14 and and CC cord-001207-yjaiybwf 226 15 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 226 16 as as RB cord-001207-yjaiybwf 226 17 well well RB cord-001207-yjaiybwf 226 18 as as IN cord-001207-yjaiybwf 226 19 an an DT cord-001207-yjaiybwf 226 20 increasing increase VBG cord-001207-yjaiybwf 226 21 diversification diversification NN cord-001207-yjaiybwf 226 22 of of IN cord-001207-yjaiybwf 226 23 virus virus NN cord-001207-yjaiybwf 226 24 species specie NNS cord-001207-yjaiybwf 226 25 by by IN cord-001207-yjaiybwf 226 26 age age NN cord-001207-yjaiybwf 226 27 . . . cord-001207-yjaiybwf 227 1 Consistent consistent JJ cord-001207-yjaiybwf 227 2 differences difference NNS cord-001207-yjaiybwf 227 3 due due JJ cord-001207-yjaiybwf 227 4 to to IN cord-001207-yjaiybwf 227 5 probiotic probiotic JJ cord-001207-yjaiybwf 227 6 feeding feeding NN cord-001207-yjaiybwf 227 7 could could MD cord-001207-yjaiybwf 227 8 not not RB cord-001207-yjaiybwf 227 9 be be VB cord-001207-yjaiybwf 227 10 identified identify VBN cord-001207-yjaiybwf 227 11 by by IN cord-001207-yjaiybwf 227 12 our -PRON- PRP$ cord-001207-yjaiybwf 227 13 metagenomic metagenomic NNP cord-001207-yjaiybwf 227 14 analysis analysis NN cord-001207-yjaiybwf 227 15 . . . cord-001207-yjaiybwf 228 1 The the DT cord-001207-yjaiybwf 228 2 results result NNS cord-001207-yjaiybwf 228 3 of of IN cord-001207-yjaiybwf 228 4 comparative comparative JJ cord-001207-yjaiybwf 228 5 pig pig NN cord-001207-yjaiybwf 228 6 virome virome NNP cord-001207-yjaiybwf 228 7 analyses analysis NNS cord-001207-yjaiybwf 228 8 may may MD cord-001207-yjaiybwf 228 9 help help VB cord-001207-yjaiybwf 228 10 to to TO cord-001207-yjaiybwf 228 11 understand understand VB cord-001207-yjaiybwf 228 12 the the DT cord-001207-yjaiybwf 228 13 complex complex JJ cord-001207-yjaiybwf 228 14 interactions interaction NNS cord-001207-yjaiybwf 228 15 between between IN cord-001207-yjaiybwf 228 16 viruses virus NNS cord-001207-yjaiybwf 228 17 , , , cord-001207-yjaiybwf 228 18 bacteria bacteria NNS cord-001207-yjaiybwf 228 19 and and CC cord-001207-yjaiybwf 228 20 the the DT cord-001207-yjaiybwf 228 21 pig pig NN cord-001207-yjaiybwf 228 22 within within IN cord-001207-yjaiybwf 228 23 the the DT cord-001207-yjaiybwf 228 24 intestinal intestinal JJ cord-001207-yjaiybwf 228 25 tract tract NN cord-001207-yjaiybwf 228 26 . . . cord-001207-yjaiybwf 229 1 Future future JJ cord-001207-yjaiybwf 229 2 research research NN cord-001207-yjaiybwf 229 3 should should MD cord-001207-yjaiybwf 229 4 focus focus VB cord-001207-yjaiybwf 229 5 on on IN cord-001207-yjaiybwf 229 6 the the DT cord-001207-yjaiybwf 229 7 optimization optimization NN cord-001207-yjaiybwf 229 8 of of IN cord-001207-yjaiybwf 229 9 the the DT cord-001207-yjaiybwf 229 10 method method NN cord-001207-yjaiybwf 229 11 in in IN cord-001207-yjaiybwf 229 12 order order NN cord-001207-yjaiybwf 229 13 to to TO cord-001207-yjaiybwf 229 14 increase increase VB cord-001207-yjaiybwf 229 15 its -PRON- PRP$ cord-001207-yjaiybwf 229 16 sensitivity sensitivity NN cord-001207-yjaiybwf 229 17 and and CC cord-001207-yjaiybwf 229 18 on on IN cord-001207-yjaiybwf 229 19 the the DT cord-001207-yjaiybwf 229 20 improvement improvement NN cord-001207-yjaiybwf 229 21 of of IN cord-001207-yjaiybwf 229 22 the the DT cord-001207-yjaiybwf 229 23 sequence sequence NN cord-001207-yjaiybwf 229 24 databases database NNS cord-001207-yjaiybwf 229 25 , , , cord-001207-yjaiybwf 229 26 especially especially RB cord-001207-yjaiybwf 229 27 regarding regard VBG cord-001207-yjaiybwf 229 28 annotated annotate VBN cord-001207-yjaiybwf 229 29 bacteriophage bacteriophage NN cord-001207-yjaiybwf 229 30 sequences sequence NNS cord-001207-yjaiybwf 229 31 . . . cord-001207-yjaiybwf 230 1 It -PRON- PRP cord-001207-yjaiybwf 230 2 will will MD cord-001207-yjaiybwf 230 3 be be VB cord-001207-yjaiybwf 230 4 interesting interesting JJ cord-001207-yjaiybwf 230 5 to to TO cord-001207-yjaiybwf 230 6 apply apply VB cord-001207-yjaiybwf 230 7 the the DT cord-001207-yjaiybwf 230 8 optimized optimize VBN cord-001207-yjaiybwf 230 9 techniques technique NNS cord-001207-yjaiybwf 230 10 to to TO cord-001207-yjaiybwf 230 11 analyse analyse VB cord-001207-yjaiybwf 230 12 the the DT cord-001207-yjaiybwf 230 13 diversity diversity NN cord-001207-yjaiybwf 230 14 of of IN cord-001207-yjaiybwf 230 15 faecal faecal JJ cord-001207-yjaiybwf 230 16 viromes virome NNS cord-001207-yjaiybwf 230 17 in in IN cord-001207-yjaiybwf 230 18 individuals individual NNS cord-001207-yjaiybwf 230 19 and and CC cord-001207-yjaiybwf 230 20 to to TO cord-001207-yjaiybwf 230 21 identify identify VB cord-001207-yjaiybwf 230 22 further further JJ cord-001207-yjaiybwf 230 23 factors factor NNS cord-001207-yjaiybwf 230 24 like like IN cord-001207-yjaiybwf 230 25 geographical geographical JJ cord-001207-yjaiybwf 230 26 origin origin NN cord-001207-yjaiybwf 230 27 or or CC cord-001207-yjaiybwf 230 28 disease disease NN cord-001207-yjaiybwf 230 29 - - HYPH cord-001207-yjaiybwf 230 30 related relate VBN cord-001207-yjaiybwf 230 31 changes change NNS cord-001207-yjaiybwf 230 32 influencing influence VBG cord-001207-yjaiybwf 230 33 its -PRON- PRP$ cord-001207-yjaiybwf 230 34 composition composition NN cord-001207-yjaiybwf 230 35 . . . cord-001207-yjaiybwf 231 1 Table table NN cord-001207-yjaiybwf 231 2 S1 S1 NNP cord-001207-yjaiybwf 231 3 Relative relative JJ cord-001207-yjaiybwf 231 4 abundance abundance NN cord-001207-yjaiybwf 231 5 of of IN cord-001207-yjaiybwf 231 6 virus virus NN cord-001207-yjaiybwf 231 7 families family NNS cord-001207-yjaiybwf 231 8 in in IN cord-001207-yjaiybwf 231 9 the the DT cord-001207-yjaiybwf 231 10 analyzed analyze VBN cord-001207-yjaiybwf 231 11 faecal faecal JJ cord-001207-yjaiybwf 231 12 viromes virome NNS cord-001207-yjaiybwf 231 13 . . . cord-001207-yjaiybwf 232 1 The the DT cord-001207-yjaiybwf 232 2 table table NN cord-001207-yjaiybwf 232 3 shows show VBZ cord-001207-yjaiybwf 232 4 the the DT cord-001207-yjaiybwf 232 5 number number NN cord-001207-yjaiybwf 232 6 of of IN cord-001207-yjaiybwf 232 7 reads read NNS cord-001207-yjaiybwf 232 8 with with IN cord-001207-yjaiybwf 232 9 sequence sequence NN cord-001207-yjaiybwf 232 10 identities identity NNS cord-001207-yjaiybwf 232 11 to to IN cord-001207-yjaiybwf 232 12 a a DT cord-001207-yjaiybwf 232 13 certain certain JJ cord-001207-yjaiybwf 232 14 virus virus NN cord-001207-yjaiybwf 232 15 family family NN cord-001207-yjaiybwf 232 16 in in IN cord-001207-yjaiybwf 232 17 relation relation NN cord-001207-yjaiybwf 232 18 to to IN cord-001207-yjaiybwf 232 19 all all DT cord-001207-yjaiybwf 232 20 virus virus NN cord-001207-yjaiybwf 232 21 reads read VBZ cord-001207-yjaiybwf 232 22 ( ( -LRB- cord-001207-yjaiybwf 232 23 in in IN cord-001207-yjaiybwf 232 24 % % NN cord-001207-yjaiybwf 232 25 ) ) -RRB- cord-001207-yjaiybwf 232 26 . . . cord-001207-yjaiybwf 233 1 Families family NNS cord-001207-yjaiybwf 233 2 showing show VBG cord-001207-yjaiybwf 233 3 an an DT cord-001207-yjaiybwf 233 4 abundance abundance NN cord-001207-yjaiybwf 233 5 of of IN cord-001207-yjaiybwf 233 6 less less JJR cord-001207-yjaiybwf 233 7 than than IN cord-001207-yjaiybwf 233 8 1 1 CD cord-001207-yjaiybwf 233 9 % % NN cord-001207-yjaiybwf 233 10 in in IN cord-001207-yjaiybwf 233 11 a a DT cord-001207-yjaiybwf 233 12 distinct distinct JJ cord-001207-yjaiybwf 233 13 faecal faecal JJ cord-001207-yjaiybwf 233 14 virome virome NN cord-001207-yjaiybwf 233 15 are be VBP cord-001207-yjaiybwf 233 16 subsumed subsume VBN cord-001207-yjaiybwf 233 17 to to IN cord-001207-yjaiybwf 233 18 other other JJ cord-001207-yjaiybwf 233 19 families family NNS cord-001207-yjaiybwf 233 20 . . . cord-001207-yjaiybwf 234 1 Families family NNS cord-001207-yjaiybwf 234 2 which which WDT cord-001207-yjaiybwf 234 3 were be VBD cord-001207-yjaiybwf 234 4 not not RB cord-001207-yjaiybwf 234 5 classified classify VBN cord-001207-yjaiybwf 234 6 by by IN cord-001207-yjaiybwf 234 7 the the DT cord-001207-yjaiybwf 234 8 International International NNP cord-001207-yjaiybwf 234 9 Committee Committee NNP cord-001207-yjaiybwf 234 10 on on IN cord-001207-yjaiybwf 234 11 Taxonomy Taxonomy NNP cord-001207-yjaiybwf 234 12 of of IN cord-001207-yjaiybwf 234 13 Viruses Viruses NNPS cord-001207-yjaiybwf 234 14 ( ( -LRB- cord-001207-yjaiybwf 234 15 ICTV ICTV NNP cord-001207-yjaiybwf 234 16 ) ) -RRB- cord-001207-yjaiybwf 234 17 are be VBP cord-001207-yjaiybwf 234 18 subsumed subsume VBN cord-001207-yjaiybwf 234 19 to to IN cord-001207-yjaiybwf 234 20 not not RB cord-001207-yjaiybwf 234 21 assigned assign VBN cord-001207-yjaiybwf 234 22 . . . cord-001207-yjaiybwf 235 1 The the DT cord-001207-yjaiybwf 235 2 group group NN cord-001207-yjaiybwf 235 3 P p NN cord-001207-yjaiybwf 235 4 received receive VBD cord-001207-yjaiybwf 235 5 the the DT cord-001207-yjaiybwf 235 6 probiotic probiotic JJ cord-001207-yjaiybwf 235 7 bacterium bacterium NN cord-001207-yjaiybwf 235 8 E. E. NNP cord-001207-yjaiybwf 235 9 faecium faecium NN cord-001207-yjaiybwf 236 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 236 2 10415 10415 CD cord-001207-yjaiybwf 236 3 ( ( -LRB- cord-001207-yjaiybwf 236 4 P p NN cord-001207-yjaiybwf 236 5 ) ) -RRB- cord-001207-yjaiybwf 236 6 and and CC cord-001207-yjaiybwf 236 7 the the DT cord-001207-yjaiybwf 236 8 group group NN cord-001207-yjaiybwf 236 9 C C NNP cord-001207-yjaiybwf 236 10 ( ( -LRB- cord-001207-yjaiybwf 236 11 C C NNP cord-001207-yjaiybwf 236 12 ) ) -RRB- cord-001207-yjaiybwf 236 13 received receive VBD cord-001207-yjaiybwf 236 14 no no DT cord-001207-yjaiybwf 236 15 probiotic probiotic NN cord-001207-yjaiybwf 236 16 . . . cord-001207-yjaiybwf 237 1 Table table NN cord-001207-yjaiybwf 237 2 S2 s2 NN cord-001207-yjaiybwf 237 3 Relative relative JJ cord-001207-yjaiybwf 237 4 abundance abundance NN cord-001207-yjaiybwf 237 5 of of IN cord-001207-yjaiybwf 237 6 bacteriophage bacteriophage NN cord-001207-yjaiybwf 237 7 species specie NNS cord-001207-yjaiybwf 237 8 among among IN cord-001207-yjaiybwf 237 9 all all DT cord-001207-yjaiybwf 237 10 bacteriophages bacteriophage NNS cord-001207-yjaiybwf 237 11 detected detect VBN cord-001207-yjaiybwf 237 12 in in IN cord-001207-yjaiybwf 237 13 the the DT cord-001207-yjaiybwf 237 14 analyzed analyze VBN cord-001207-yjaiybwf 237 15 faecal faecal JJ cord-001207-yjaiybwf 237 16 viromes virome NNS cord-001207-yjaiybwf 237 17 . . . cord-001207-yjaiybwf 238 1 The the DT cord-001207-yjaiybwf 238 2 table table NN cord-001207-yjaiybwf 238 3 shows show VBZ cord-001207-yjaiybwf 238 4 the the DT cord-001207-yjaiybwf 238 5 number number NN cord-001207-yjaiybwf 238 6 of of IN cord-001207-yjaiybwf 238 7 reads read NNS cord-001207-yjaiybwf 238 8 with with IN cord-001207-yjaiybwf 238 9 sequence sequence NN cord-001207-yjaiybwf 238 10 identities identity NNS cord-001207-yjaiybwf 238 11 to to IN cord-001207-yjaiybwf 238 12 a a DT cord-001207-yjaiybwf 238 13 certain certain JJ cord-001207-yjaiybwf 238 14 bacteriophage bacteriophage NN cord-001207-yjaiybwf 238 15 species specie NNS cord-001207-yjaiybwf 238 16 in in IN cord-001207-yjaiybwf 238 17 relation relation NN cord-001207-yjaiybwf 238 18 to to IN cord-001207-yjaiybwf 238 19 all all DT cord-001207-yjaiybwf 238 20 bacteriophage bacteriophage NN cord-001207-yjaiybwf 238 21 reads read VBZ cord-001207-yjaiybwf 238 22 ( ( -LRB- cord-001207-yjaiybwf 238 23 in in IN cord-001207-yjaiybwf 238 24 % % NN cord-001207-yjaiybwf 238 25 ) ) -RRB- cord-001207-yjaiybwf 238 26 . . . cord-001207-yjaiybwf 239 1 Bacteriophage bacteriophage NN cord-001207-yjaiybwf 239 2 species specie NNS cord-001207-yjaiybwf 239 3 showing show VBG cord-001207-yjaiybwf 239 4 an an DT cord-001207-yjaiybwf 239 5 abundance abundance NN cord-001207-yjaiybwf 239 6 of of IN cord-001207-yjaiybwf 239 7 less less JJR cord-001207-yjaiybwf 239 8 than than IN cord-001207-yjaiybwf 239 9 1 1 CD cord-001207-yjaiybwf 239 10 % % NN cord-001207-yjaiybwf 239 11 in in IN cord-001207-yjaiybwf 239 12 a a DT cord-001207-yjaiybwf 239 13 distinct distinct JJ cord-001207-yjaiybwf 239 14 faecal faecal JJ cord-001207-yjaiybwf 239 15 virome virome NN cord-001207-yjaiybwf 239 16 are be VBP cord-001207-yjaiybwf 239 17 subsumed subsume VBN cord-001207-yjaiybwf 239 18 ( ( -LRB- cord-001207-yjaiybwf 239 19 , , , cord-001207-yjaiybwf 239 20 1 1 CD cord-001207-yjaiybwf 239 21 % % NN cord-001207-yjaiybwf 239 22 ) ) -RRB- cord-001207-yjaiybwf 239 23 . . . cord-001207-yjaiybwf 240 1 The the DT cord-001207-yjaiybwf 240 2 group group NN cord-001207-yjaiybwf 240 3 P p NN cord-001207-yjaiybwf 240 4 received receive VBD cord-001207-yjaiybwf 240 5 the the DT cord-001207-yjaiybwf 240 6 probiotic probiotic JJ cord-001207-yjaiybwf 240 7 bacterium bacterium NN cord-001207-yjaiybwf 240 8 E. E. NNP cord-001207-yjaiybwf 240 9 faecium faecium NN cord-001207-yjaiybwf 241 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 241 2 10415 10415 CD cord-001207-yjaiybwf 241 3 ( ( -LRB- cord-001207-yjaiybwf 241 4 P p NN cord-001207-yjaiybwf 241 5 ) ) -RRB- cord-001207-yjaiybwf 241 6 and and CC cord-001207-yjaiybwf 241 7 the the DT cord-001207-yjaiybwf 241 8 group group NN cord-001207-yjaiybwf 241 9 C C NNP cord-001207-yjaiybwf 241 10 ( ( -LRB- cord-001207-yjaiybwf 241 11 C C NNP cord-001207-yjaiybwf 241 12 ) ) -RRB- cord-001207-yjaiybwf 241 13 received receive VBD cord-001207-yjaiybwf 241 14 no no DT cord-001207-yjaiybwf 241 15 probiotic probiotic NN cord-001207-yjaiybwf 241 16 . . . cord-001207-yjaiybwf 242 1 ( ( -LRB- cord-001207-yjaiybwf 242 2 PDF PDF NNP cord-001207-yjaiybwf 242 3 ) ) -RRB- cord-001207-yjaiybwf 242 4 _SP cord-001207-yjaiybwf 242 5 Table table NN cord-001207-yjaiybwf 242 6 S3 S3 NNP cord-001207-yjaiybwf 242 7 Relative relative JJ cord-001207-yjaiybwf 242 8 abundance abundance NN cord-001207-yjaiybwf 242 9 of of IN cord-001207-yjaiybwf 242 10 mammalian mammalian JJ cord-001207-yjaiybwf 242 11 virus virus NN cord-001207-yjaiybwf 242 12 genera genera VBP cord-001207-yjaiybwf 242 13 among among IN cord-001207-yjaiybwf 242 14 all all DT cord-001207-yjaiybwf 242 15 animal animal NN cord-001207-yjaiybwf 242 16 viruses virus NNS cord-001207-yjaiybwf 242 17 detected detect VBN cord-001207-yjaiybwf 242 18 in in IN cord-001207-yjaiybwf 242 19 the the DT cord-001207-yjaiybwf 242 20 analyzed analyze VBN cord-001207-yjaiybwf 242 21 faecal faecal JJ cord-001207-yjaiybwf 242 22 viromes virome NNS cord-001207-yjaiybwf 242 23 . . . cord-001207-yjaiybwf 243 1 The the DT cord-001207-yjaiybwf 243 2 table table NN cord-001207-yjaiybwf 243 3 shows show VBZ cord-001207-yjaiybwf 243 4 the the DT cord-001207-yjaiybwf 243 5 number number NN cord-001207-yjaiybwf 243 6 of of IN cord-001207-yjaiybwf 243 7 reads read NNS cord-001207-yjaiybwf 243 8 with with IN cord-001207-yjaiybwf 243 9 sequence sequence NN cord-001207-yjaiybwf 243 10 identities identity NNS cord-001207-yjaiybwf 243 11 to to IN cord-001207-yjaiybwf 243 12 a a DT cord-001207-yjaiybwf 243 13 certain certain JJ cord-001207-yjaiybwf 243 14 mammalian mammalian JJ cord-001207-yjaiybwf 243 15 virus virus NN cord-001207-yjaiybwf 243 16 genus genus NN cord-001207-yjaiybwf 243 17 in in IN cord-001207-yjaiybwf 243 18 relation relation NN cord-001207-yjaiybwf 243 19 to to IN cord-001207-yjaiybwf 243 20 all all DT cord-001207-yjaiybwf 243 21 animal animal NN cord-001207-yjaiybwf 243 22 virus virus NN cord-001207-yjaiybwf 243 23 reads read VBZ cord-001207-yjaiybwf 243 24 ( ( -LRB- cord-001207-yjaiybwf 243 25 in in IN cord-001207-yjaiybwf 243 26 % % NN cord-001207-yjaiybwf 243 27 ) ) -RRB- cord-001207-yjaiybwf 243 28 . . . cord-001207-yjaiybwf 244 1 Mammalian mammalian JJ cord-001207-yjaiybwf 244 2 viruses virus NNS cord-001207-yjaiybwf 244 3 , , , cord-001207-yjaiybwf 244 4 which which WDT cord-001207-yjaiybwf 244 5 are be VBP cord-001207-yjaiybwf 244 6 so so RB cord-001207-yjaiybwf 244 7 far far RB cord-001207-yjaiybwf 244 8 not not RB cord-001207-yjaiybwf 244 9 assigned assign VBN cord-001207-yjaiybwf 244 10 to to IN cord-001207-yjaiybwf 244 11 a a DT cord-001207-yjaiybwf 244 12 certain certain JJ cord-001207-yjaiybwf 244 13 genus genus NN cord-001207-yjaiybwf 244 14 , , , cord-001207-yjaiybwf 244 15 are be VBP cord-001207-yjaiybwf 244 16 indicated indicate VBN cord-001207-yjaiybwf 244 17 in in IN cord-001207-yjaiybwf 244 18 apostrophes apostrophe NNS cord-001207-yjaiybwf 244 19 . . . cord-001207-yjaiybwf 245 1 Mammalian mammalian JJ cord-001207-yjaiybwf 245 2 virus virus NN cord-001207-yjaiybwf 245 3 genera genera VBP cord-001207-yjaiybwf 245 4 showing show VBG cord-001207-yjaiybwf 245 5 an an DT cord-001207-yjaiybwf 245 6 abundance abundance NN cord-001207-yjaiybwf 245 7 of of IN cord-001207-yjaiybwf 245 8 less less JJR cord-001207-yjaiybwf 245 9 than than IN cord-001207-yjaiybwf 245 10 1 1 CD cord-001207-yjaiybwf 245 11 % % NN cord-001207-yjaiybwf 245 12 in in IN cord-001207-yjaiybwf 245 13 a a DT cord-001207-yjaiybwf 245 14 distinct distinct JJ cord-001207-yjaiybwf 245 15 faecal faecal JJ cord-001207-yjaiybwf 245 16 virome virome NN cord-001207-yjaiybwf 245 17 are be VBP cord-001207-yjaiybwf 245 18 subsumed subsume VBN cord-001207-yjaiybwf 245 19 ( ( -LRB- cord-001207-yjaiybwf 245 20 genera genus NNS cord-001207-yjaiybwf 245 21 , , , cord-001207-yjaiybwf 245 22 1 1 CD cord-001207-yjaiybwf 245 23 % % NN cord-001207-yjaiybwf 245 24 ) ) -RRB- cord-001207-yjaiybwf 245 25 . . . cord-001207-yjaiybwf 246 1 Viruses virus NNS cord-001207-yjaiybwf 246 2 from from IN cord-001207-yjaiybwf 246 3 non non JJ cord-001207-yjaiybwf 246 4 - - JJ cord-001207-yjaiybwf 246 5 mammalian mammalian JJ cord-001207-yjaiybwf 246 6 hosts host NNS cord-001207-yjaiybwf 246 7 are be VBP cord-001207-yjaiybwf 246 8 subsumed subsume VBN cord-001207-yjaiybwf 246 9 to to IN cord-001207-yjaiybwf 246 10 non non JJ cord-001207-yjaiybwf 246 11 mammalian mammalian JJ cord-001207-yjaiybwf 246 12 viruses virus NNS cord-001207-yjaiybwf 246 13 . . . cord-001207-yjaiybwf 247 1 The the DT cord-001207-yjaiybwf 247 2 group group NN cord-001207-yjaiybwf 247 3 P p NN cord-001207-yjaiybwf 247 4 received receive VBD cord-001207-yjaiybwf 247 5 the the DT cord-001207-yjaiybwf 247 6 probiotic probiotic JJ cord-001207-yjaiybwf 247 7 bacterium bacterium NN cord-001207-yjaiybwf 247 8 E. E. NNP cord-001207-yjaiybwf 247 9 faecium faecium NN cord-001207-yjaiybwf 248 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 248 2 10415 10415 CD cord-001207-yjaiybwf 248 3 ( ( -LRB- cord-001207-yjaiybwf 248 4 P p NN cord-001207-yjaiybwf 248 5 ) ) -RRB- cord-001207-yjaiybwf 248 6 and and CC cord-001207-yjaiybwf 248 7 the the DT cord-001207-yjaiybwf 248 8 group group NN cord-001207-yjaiybwf 248 9 C C NNP cord-001207-yjaiybwf 248 10 ( ( -LRB- cord-001207-yjaiybwf 248 11 C C NNP cord-001207-yjaiybwf 248 12 ) ) -RRB- cord-001207-yjaiybwf 248 13 received receive VBD cord-001207-yjaiybwf 248 14 no no DT cord-001207-yjaiybwf 248 15 probiotic probiotic NN cord-001207-yjaiybwf 248 16 . . . cord-001207-yjaiybwf 249 1 ( ( -LRB- cord-001207-yjaiybwf 249 2 PDF PDF NNP cord-001207-yjaiybwf 249 3 ) ) -RRB- cord-001207-yjaiybwf 250 1 The the DT cord-001207-yjaiybwf 250 2 human human JJ cord-001207-yjaiybwf 250 3 gut gut NN cord-001207-yjaiybwf 250 4 virome virome NNP cord-001207-yjaiybwf 250 5 : : : cord-001207-yjaiybwf 251 1 Inter inter JJ cord-001207-yjaiybwf 251 2 - - JJ cord-001207-yjaiybwf 251 3 individual individual JJ cord-001207-yjaiybwf 251 4 variation variation NN cord-001207-yjaiybwf 251 5 and and CC cord-001207-yjaiybwf 251 6 dynamic dynamic JJ cord-001207-yjaiybwf 251 7 response response NN cord-001207-yjaiybwf 251 8 to to IN cord-001207-yjaiybwf 251 9 diet diet NN cord-001207-yjaiybwf 252 1 The the DT cord-001207-yjaiybwf 252 2 fecal fecal JJ cord-001207-yjaiybwf 252 3 virome virome NN cord-001207-yjaiybwf 252 4 of of IN cord-001207-yjaiybwf 252 5 pigs pig NNS cord-001207-yjaiybwf 252 6 on on IN cord-001207-yjaiybwf 252 7 a a DT cord-001207-yjaiybwf 252 8 high high JJ cord-001207-yjaiybwf 252 9 - - HYPH cord-001207-yjaiybwf 252 10 density density NN cord-001207-yjaiybwf 252 11 farm farm NN cord-001207-yjaiybwf 252 12 Antibiotic antibiotic JJ cord-001207-yjaiybwf 252 13 treatment treatment NN cord-001207-yjaiybwf 252 14 expands expand VBZ cord-001207-yjaiybwf 252 15 the the DT cord-001207-yjaiybwf 252 16 resistance resistance NN cord-001207-yjaiybwf 252 17 reservoir reservoir NN cord-001207-yjaiybwf 252 18 and and CC cord-001207-yjaiybwf 252 19 ecological ecological JJ cord-001207-yjaiybwf 252 20 network network NN cord-001207-yjaiybwf 252 21 of of IN cord-001207-yjaiybwf 252 22 the the DT cord-001207-yjaiybwf 252 23 phage phage NN cord-001207-yjaiybwf 252 24 metagenome metagenome NNP cord-001207-yjaiybwf 252 25 Genome Genome NNP cord-001207-yjaiybwf 252 26 signature signature NN cord-001207-yjaiybwf 252 27 - - HYPH cord-001207-yjaiybwf 252 28 based base VBN cord-001207-yjaiybwf 252 29 dissection dissection NN cord-001207-yjaiybwf 252 30 of of IN cord-001207-yjaiybwf 252 31 human human JJ cord-001207-yjaiybwf 252 32 gut gut NN cord-001207-yjaiybwf 252 33 metagenomes metagenome NNS cord-001207-yjaiybwf 252 34 to to TO cord-001207-yjaiybwf 252 35 extract extract VB cord-001207-yjaiybwf 252 36 subliminal subliminal JJ cord-001207-yjaiybwf 252 37 viral viral JJ cord-001207-yjaiybwf 252 38 sequences sequence NNS cord-001207-yjaiybwf 252 39 Analysis Analysis NNP cord-001207-yjaiybwf 252 40 of of IN cord-001207-yjaiybwf 252 41 a a DT cord-001207-yjaiybwf 252 42 viral viral JJ cord-001207-yjaiybwf 252 43 metagenomic metagenomic JJ cord-001207-yjaiybwf 252 44 library library NN cord-001207-yjaiybwf 252 45 from from IN cord-001207-yjaiybwf 252 46 200 200 CD cord-001207-yjaiybwf 252 47 m m CD cord-001207-yjaiybwf 252 48 depth depth NN cord-001207-yjaiybwf 252 49 in in IN cord-001207-yjaiybwf 252 50 Monterey Monterey NNP cord-001207-yjaiybwf 252 51 Bay Bay NNP cord-001207-yjaiybwf 252 52 , , , cord-001207-yjaiybwf 252 53 California California NNP cord-001207-yjaiybwf 252 54 constructed construct VBN cord-001207-yjaiybwf 252 55 by by IN cord-001207-yjaiybwf 252 56 direct direct JJ cord-001207-yjaiybwf 252 57 shotgun shotgun NN cord-001207-yjaiybwf 252 58 cloning clone VBG cord-001207-yjaiybwf 252 59 Prevention prevention NN cord-001207-yjaiybwf 252 60 and and CC cord-001207-yjaiybwf 252 61 treatment treatment NN cord-001207-yjaiybwf 252 62 of of IN cord-001207-yjaiybwf 252 63 enteric enteric JJ cord-001207-yjaiybwf 252 64 viral viral JJ cord-001207-yjaiybwf 252 65 infections infection NNS cord-001207-yjaiybwf 252 66 : : : cord-001207-yjaiybwf 252 67 possible possible JJ cord-001207-yjaiybwf 252 68 benefits benefit NNS cord-001207-yjaiybwf 252 69 of of IN cord-001207-yjaiybwf 252 70 probiotic probiotic JJ cord-001207-yjaiybwf 252 71 bacteria bacteria NNS cord-001207-yjaiybwf 252 72 . . . cord-001207-yjaiybwf 253 1 Microbes microbe NNS cord-001207-yjaiybwf 253 2 Infect infect VBP cord-001207-yjaiybwf 253 3 RNA RNA NNP cord-001207-yjaiybwf 253 4 Viral Viral NNP cord-001207-yjaiybwf 253 5 Community Community NNP cord-001207-yjaiybwf 253 6 in in IN cord-001207-yjaiybwf 253 7 Human Human NNP cord-001207-yjaiybwf 253 8 Feces fece NNS cord-001207-yjaiybwf 253 9 : : : cord-001207-yjaiybwf 254 1 Prevalence prevalence NN cord-001207-yjaiybwf 254 2 of of IN cord-001207-yjaiybwf 254 3 Plant Plant NNP cord-001207-yjaiybwf 254 4 Pathogenic Pathogenic NNP cord-001207-yjaiybwf 254 5 Viruses Viruses NNPS cord-001207-yjaiybwf 254 6 Metagenomic Metagenomic NNP cord-001207-yjaiybwf 254 7 analyses analysis NNS cord-001207-yjaiybwf 254 8 of of IN cord-001207-yjaiybwf 254 9 an an DT cord-001207-yjaiybwf 254 10 uncultured uncultured JJ cord-001207-yjaiybwf 254 11 viral viral JJ cord-001207-yjaiybwf 254 12 community community NN cord-001207-yjaiybwf 254 13 from from IN cord-001207-yjaiybwf 254 14 human human JJ cord-001207-yjaiybwf 254 15 feces fece NNS cord-001207-yjaiybwf 254 16 Viruses virus NNS cord-001207-yjaiybwf 254 17 in in IN cord-001207-yjaiybwf 254 18 the the DT cord-001207-yjaiybwf 254 19 faecal faecal JJ cord-001207-yjaiybwf 254 20 microbiota microbiota NN cord-001207-yjaiybwf 254 21 of of IN cord-001207-yjaiybwf 254 22 monozygotic monozygotic JJ cord-001207-yjaiybwf 254 23 twins twin NNS cord-001207-yjaiybwf 254 24 and and CC cord-001207-yjaiybwf 254 25 their -PRON- PRP$ cord-001207-yjaiybwf 254 26 mothers mother NNS cord-001207-yjaiybwf 254 27 Simultaneous simultaneous JJ cord-001207-yjaiybwf 254 28 identification identification NN cord-001207-yjaiybwf 254 29 of of IN cord-001207-yjaiybwf 254 30 DNA DNA NNP cord-001207-yjaiybwf 254 31 and and CC cord-001207-yjaiybwf 254 32 RNA RNA NNP cord-001207-yjaiybwf 254 33 viruses virus NNS cord-001207-yjaiybwf 254 34 present present JJ cord-001207-yjaiybwf 254 35 in in IN cord-001207-yjaiybwf 254 36 pig pig NN cord-001207-yjaiybwf 254 37 faeces faece NNS cord-001207-yjaiybwf 254 38 using use VBG cord-001207-yjaiybwf 254 39 process process NN cord-001207-yjaiybwf 254 40 - - HYPH cord-001207-yjaiybwf 254 41 controlled control VBN cord-001207-yjaiybwf 254 42 deep deep JJ cord-001207-yjaiybwf 254 43 sequencing sequencing NN cord-001207-yjaiybwf 254 44 Diversity diversity NN cord-001207-yjaiybwf 254 45 of of IN cord-001207-yjaiybwf 254 46 viruses virus NNS cord-001207-yjaiybwf 254 47 detected detect VBN cord-001207-yjaiybwf 254 48 by by IN cord-001207-yjaiybwf 254 49 deep deep JJ cord-001207-yjaiybwf 254 50 sequencing sequencing NN cord-001207-yjaiybwf 254 51 in in IN cord-001207-yjaiybwf 254 52 pigs pig NNS cord-001207-yjaiybwf 254 53 from from IN cord-001207-yjaiybwf 254 54 a a DT cord-001207-yjaiybwf 254 55 common common JJ cord-001207-yjaiybwf 254 56 background background NN cord-001207-yjaiybwf 254 57 Different different JJ cord-001207-yjaiybwf 254 58 virulence virulence NN cord-001207-yjaiybwf 254 59 of of IN cord-001207-yjaiybwf 254 60 porcine porcine JJ cord-001207-yjaiybwf 254 61 and and CC cord-001207-yjaiybwf 254 62 porcine porcine JJ cord-001207-yjaiybwf 254 63 - - HYPH cord-001207-yjaiybwf 254 64 like like JJ cord-001207-yjaiybwf 254 65 bovine bovine JJ cord-001207-yjaiybwf 254 66 rotavirus rotavirus NN cord-001207-yjaiybwf 254 67 strains strain NNS cord-001207-yjaiybwf 254 68 with with IN cord-001207-yjaiybwf 254 69 genetically genetically RB cord-001207-yjaiybwf 254 70 nearly nearly RB cord-001207-yjaiybwf 254 71 identical identical JJ cord-001207-yjaiybwf 254 72 genomes genome NNS cord-001207-yjaiybwf 254 73 in in IN cord-001207-yjaiybwf 254 74 piglets piglet NNS cord-001207-yjaiybwf 254 75 and and CC cord-001207-yjaiybwf 254 76 calves calf NNS cord-001207-yjaiybwf 254 77 Diversity diversity NN cord-001207-yjaiybwf 254 78 and and CC cord-001207-yjaiybwf 254 79 zoonotic zoonotic JJ cord-001207-yjaiybwf 254 80 potential potential NN cord-001207-yjaiybwf 254 81 of of IN cord-001207-yjaiybwf 254 82 rotaviruses rotavirus NNS cord-001207-yjaiybwf 254 83 in in IN cord-001207-yjaiybwf 254 84 swine swine NN cord-001207-yjaiybwf 254 85 and and CC cord-001207-yjaiybwf 254 86 cattle cattle NNS cord-001207-yjaiybwf 254 87 across across IN cord-001207-yjaiybwf 254 88 Europe Europe NNP cord-001207-yjaiybwf 254 89 Zoonotic Zoonotic NNP cord-001207-yjaiybwf 254 90 aspects aspect NNS cord-001207-yjaiybwf 254 91 of of IN cord-001207-yjaiybwf 254 92 rotaviruses rotaviruses NNP cord-001207-yjaiybwf 254 93 Occurrence occurrence NN cord-001207-yjaiybwf 254 94 and and CC cord-001207-yjaiybwf 254 95 investigation investigation NN cord-001207-yjaiybwf 254 96 of of IN cord-001207-yjaiybwf 254 97 enteric enteric JJ cord-001207-yjaiybwf 254 98 viral viral JJ cord-001207-yjaiybwf 254 99 infections infection NNS cord-001207-yjaiybwf 254 100 in in IN cord-001207-yjaiybwf 254 101 pigs pig NNS cord-001207-yjaiybwf 254 102 with with IN cord-001207-yjaiybwf 254 103 diarrhea diarrhea NN cord-001207-yjaiybwf 254 104 in in IN cord-001207-yjaiybwf 254 105 China China NNP cord-001207-yjaiybwf 254 106 Molecular Molecular NNP cord-001207-yjaiybwf 254 107 detection detection NN cord-001207-yjaiybwf 254 108 of of IN cord-001207-yjaiybwf 254 109 porcine porcine JJ cord-001207-yjaiybwf 254 110 kobuviruses kobuviruse NNS cord-001207-yjaiybwf 254 111 in in IN cord-001207-yjaiybwf 254 112 Italian italian JJ cord-001207-yjaiybwf 254 113 swine swine NN cord-001207-yjaiybwf 254 114 Identification identification NN cord-001207-yjaiybwf 254 115 and and CC cord-001207-yjaiybwf 254 116 molecular molecular JJ cord-001207-yjaiybwf 254 117 characterization characterization NN cord-001207-yjaiybwf 254 118 of of IN cord-001207-yjaiybwf 254 119 porcine porcine JJ cord-001207-yjaiybwf 254 120 kobuvirus kobuvirus NN cord-001207-yjaiybwf 254 121 in in IN cord-001207-yjaiybwf 254 122 U. U. NNP cord-001207-yjaiybwf 254 123 S. S. NNP cord-001207-yjaiybwf 254 124 swine swine NN cord-001207-yjaiybwf 254 125 . . . cord-001207-yjaiybwf 255 1 Virus virus NN cord-001207-yjaiybwf 255 2 Genes gene NNS cord-001207-yjaiybwf 256 1 A a DT cord-001207-yjaiybwf 256 2 divergent divergent JJ cord-001207-yjaiybwf 256 3 clade clade NN cord-001207-yjaiybwf 256 4 of of IN cord-001207-yjaiybwf 256 5 circular circular JJ cord-001207-yjaiybwf 256 6 single single RB cord-001207-yjaiybwf 256 7 - - HYPH cord-001207-yjaiybwf 256 8 stranded strand VBN cord-001207-yjaiybwf 256 9 DNA dna NN cord-001207-yjaiybwf 256 10 viruses virus NNS cord-001207-yjaiybwf 256 11 from from IN cord-001207-yjaiybwf 256 12 pig pig NN cord-001207-yjaiybwf 256 13 feces fece NNS cord-001207-yjaiybwf 257 1 Emerging emerge VBG cord-001207-yjaiybwf 257 2 and and CC cord-001207-yjaiybwf 257 3 Re Re NNS cord-001207-yjaiybwf 257 4 - - JJ cord-001207-yjaiybwf 257 5 emerging emerge VBG cord-001207-yjaiybwf 257 6 Swine swine NN cord-001207-yjaiybwf 257 7 Viruses virus NNS cord-001207-yjaiybwf 257 8 Complete complete VBP cord-001207-yjaiybwf 257 9 genome genome NN cord-001207-yjaiybwf 257 10 analysis analysis NN cord-001207-yjaiybwf 257 11 of of IN cord-001207-yjaiybwf 257 12 porcine porcine JJ cord-001207-yjaiybwf 257 13 enterovirus enterovirus NN cord-001207-yjaiybwf 257 14 B b NN cord-001207-yjaiybwf 257 15 isolated isolate VBN cord-001207-yjaiybwf 257 16 in in IN cord-001207-yjaiybwf 257 17 Korea Korea NNP cord-001207-yjaiybwf 257 18 Characterization Characterization NNP cord-001207-yjaiybwf 257 19 of of IN cord-001207-yjaiybwf 257 20 a a DT cord-001207-yjaiybwf 257 21 novel novel JJ cord-001207-yjaiybwf 257 22 porcine porcine JJ cord-001207-yjaiybwf 257 23 enterovirus enterovirus NN cord-001207-yjaiybwf 257 24 in in IN cord-001207-yjaiybwf 257 25 domestic domestic JJ cord-001207-yjaiybwf 257 26 pig pig NN cord-001207-yjaiybwf 257 27 in in IN cord-001207-yjaiybwf 257 28 Hungary Hungary NNP cord-001207-yjaiybwf 257 29 Astrovirus Astrovirus NNP cord-001207-yjaiybwf 257 30 infections infection NNS cord-001207-yjaiybwf 257 31 in in IN cord-001207-yjaiybwf 257 32 humans human NNS cord-001207-yjaiybwf 257 33 and and CC cord-001207-yjaiybwf 257 34 animals animal NNS cord-001207-yjaiybwf 258 1 -molecular -molecular JJ cord-001207-yjaiybwf 258 2 biology biology NN cord-001207-yjaiybwf 258 3 , , , cord-001207-yjaiybwf 258 4 genetic genetic JJ cord-001207-yjaiybwf 258 5 diversity diversity NN cord-001207-yjaiybwf 258 6 , , , cord-001207-yjaiybwf 258 7 and and CC cord-001207-yjaiybwf 258 8 interspecies interspecies NN cord-001207-yjaiybwf 258 9 transmissions transmission NNS cord-001207-yjaiybwf 259 1 Rapid rapid JJ cord-001207-yjaiybwf 259 2 evolution evolution NN cord-001207-yjaiybwf 259 3 of of IN cord-001207-yjaiybwf 259 4 the the DT cord-001207-yjaiybwf 259 5 human human JJ cord-001207-yjaiybwf 259 6 gut gut NN cord-001207-yjaiybwf 259 7 virome virome NN cord-001207-yjaiybwf 259 8 Viral viral JJ cord-001207-yjaiybwf 259 9 diversity diversity NN cord-001207-yjaiybwf 259 10 and and CC cord-001207-yjaiybwf 259 11 dynamics dynamic NNS cord-001207-yjaiybwf 259 12 in in IN cord-001207-yjaiybwf 259 13 an an DT cord-001207-yjaiybwf 259 14 infant infant NN cord-001207-yjaiybwf 259 15 gut gut NN cord-001207-yjaiybwf 259 16 Current current JJ cord-001207-yjaiybwf 259 17 level level NN cord-001207-yjaiybwf 259 18 of of IN cord-001207-yjaiybwf 259 19 consensus consensus NN cord-001207-yjaiybwf 259 20 on on IN cord-001207-yjaiybwf 259 21 probiotic probiotic JJ cord-001207-yjaiybwf 259 22 science science NN cord-001207-yjaiybwf 259 23 - - HYPH cord-001207-yjaiybwf 259 24 report report NN cord-001207-yjaiybwf 259 25 of of IN cord-001207-yjaiybwf 259 26 an an DT cord-001207-yjaiybwf 259 27 expert expert JJ cord-001207-yjaiybwf 259 28 meeting meeting NN cord-001207-yjaiybwf 259 29 - - : cord-001207-yjaiybwf 259 30 London London NNP cord-001207-yjaiybwf 259 31 . . . cord-001207-yjaiybwf 260 1 Gut Gut NNP cord-001207-yjaiybwf 260 2 Microbes Microbes NNPS cord-001207-yjaiybwf 260 3 Meta Meta NNP cord-001207-yjaiybwf 260 4 - - HYPH cord-001207-yjaiybwf 260 5 analysis analysis NN cord-001207-yjaiybwf 260 6 : : : cord-001207-yjaiybwf 260 7 the the DT cord-001207-yjaiybwf 260 8 effects effect NNS cord-001207-yjaiybwf 260 9 of of IN cord-001207-yjaiybwf 260 10 Lactobacillus lactobacillus NN cord-001207-yjaiybwf 260 11 rhamnosus rhamnosus NN cord-001207-yjaiybwf 260 12 GG GG NNP cord-001207-yjaiybwf 260 13 supplementation supplementation NN cord-001207-yjaiybwf 260 14 for for IN cord-001207-yjaiybwf 260 15 the the DT cord-001207-yjaiybwf 260 16 prevention prevention NN cord-001207-yjaiybwf 260 17 of of IN cord-001207-yjaiybwf 260 18 healthcare healthcare NN cord-001207-yjaiybwf 260 19 - - HYPH cord-001207-yjaiybwf 260 20 associated associate VBN cord-001207-yjaiybwf 260 21 diarrhoea diarrhoea NN cord-001207-yjaiybwf 260 22 in in IN cord-001207-yjaiybwf 260 23 children child NNS cord-001207-yjaiybwf 260 24 Probiotics probiotic NNS cord-001207-yjaiybwf 260 25 for for IN cord-001207-yjaiybwf 260 26 prevention prevention NN cord-001207-yjaiybwf 260 27 and and CC cord-001207-yjaiybwf 260 28 treatment treatment NN cord-001207-yjaiybwf 260 29 of of IN cord-001207-yjaiybwf 260 30 diarrhea diarrhea NN cord-001207-yjaiybwf 261 1 The the DT cord-001207-yjaiybwf 261 2 comparition comparition NN cord-001207-yjaiybwf 261 3 of of IN cord-001207-yjaiybwf 261 4 the the DT cord-001207-yjaiybwf 261 5 efficacy efficacy NN cord-001207-yjaiybwf 261 6 of of IN cord-001207-yjaiybwf 261 7 two two CD cord-001207-yjaiybwf 261 8 different different JJ cord-001207-yjaiybwf 261 9 probiotics probiotic NNS cord-001207-yjaiybwf 261 10 in in IN cord-001207-yjaiybwf 261 11 rotavirus rotavirus JJ cord-001207-yjaiybwf 261 12 gastroenteritis gastroenteritis NN cord-001207-yjaiybwf 261 13 in in IN cord-001207-yjaiybwf 261 14 children child NNS cord-001207-yjaiybwf 261 15 Dose dose NN cord-001207-yjaiybwf 261 16 - - HYPH cord-001207-yjaiybwf 261 17 dependent dependent JJ cord-001207-yjaiybwf 261 18 effect effect NN cord-001207-yjaiybwf 261 19 of of IN cord-001207-yjaiybwf 261 20 Lactobacillus lactobacillus NN cord-001207-yjaiybwf 261 21 rhamnosus rhamnosus NN cord-001207-yjaiybwf 261 22 on on IN cord-001207-yjaiybwf 261 23 quantitative quantitative JJ cord-001207-yjaiybwf 261 24 reduction reduction NN cord-001207-yjaiybwf 261 25 of of IN cord-001207-yjaiybwf 261 26 faecal faecal JJ cord-001207-yjaiybwf 261 27 rotavirus rotavirus NN cord-001207-yjaiybwf 261 28 shedding shed VBG cord-001207-yjaiybwf 261 29 in in IN cord-001207-yjaiybwf 261 30 children child NNS cord-001207-yjaiybwf 261 31 Feeding feed VBG cord-001207-yjaiybwf 261 32 of of IN cord-001207-yjaiybwf 261 33 the the DT cord-001207-yjaiybwf 261 34 probiotic probiotic JJ cord-001207-yjaiybwf 261 35 bacterium bacterium NN cord-001207-yjaiybwf 261 36 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 261 37 faecium faecium NN cord-001207-yjaiybwf 261 38 NCIMB NCIMB NNP cord-001207-yjaiybwf 261 39 10415 10415 CD cord-001207-yjaiybwf 261 40 differentially differentially RB cord-001207-yjaiybwf 261 41 affects affect VBZ cord-001207-yjaiybwf 261 42 shedding shedding NN cord-001207-yjaiybwf 261 43 of of IN cord-001207-yjaiybwf 261 44 enteric enteric JJ cord-001207-yjaiybwf 261 45 viruses virus NNS cord-001207-yjaiybwf 261 46 in in IN cord-001207-yjaiybwf 261 47 pigs pig NNS cord-001207-yjaiybwf 262 1 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 262 2 faecium faecium NN cord-001207-yjaiybwf 263 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 264 1 10415 10415 CD cord-001207-yjaiybwf 264 2 supplementation supplementation NN cord-001207-yjaiybwf 264 3 affects affect VBZ cord-001207-yjaiybwf 264 4 intestinal intestinal JJ cord-001207-yjaiybwf 264 5 immuneassociated immuneassociate VBN cord-001207-yjaiybwf 264 6 gene gene NN cord-001207-yjaiybwf 264 7 expression expression NN cord-001207-yjaiybwf 264 8 in in IN cord-001207-yjaiybwf 264 9 post post JJ cord-001207-yjaiybwf 264 10 - - JJ cord-001207-yjaiybwf 264 11 weaning weaning JJ cord-001207-yjaiybwf 264 12 piglets piglet NNS cord-001207-yjaiybwf 264 13 . . . cord-001207-yjaiybwf 265 1 Manuscript Manuscript NNP cord-001207-yjaiybwf 265 2 Number number NN cord-001207-yjaiybwf 265 3 : : : cord-001207-yjaiybwf 265 4 accepted accept VBN cord-001207-yjaiybwf 265 5 but but CC cord-001207-yjaiybwf 265 6 unpublished unpublished JJ cord-001207-yjaiybwf 265 7 so so RB cord-001207-yjaiybwf 265 8 far far RB cord-001207-yjaiybwf 265 9 Impact Impact NNP cord-001207-yjaiybwf 265 10 of of IN cord-001207-yjaiybwf 265 11 the the DT cord-001207-yjaiybwf 265 12 probiotic probiotic JJ cord-001207-yjaiybwf 265 13 bacteria bacteria NNS cord-001207-yjaiybwf 265 14 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 265 15 faecium faecium NN cord-001207-yjaiybwf 266 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 266 2 10415 10415 CD cord-001207-yjaiybwf 267 1 ( ( -LRB- cord-001207-yjaiybwf 267 2 SF68 SF68 NNP cord-001207-yjaiybwf 267 3 ) ) -RRB- cord-001207-yjaiybwf 267 4 and and CC cord-001207-yjaiybwf 267 5 Bacillus Bacillus NNP cord-001207-yjaiybwf 267 6 cereus cereus NN cord-001207-yjaiybwf 267 7 var var NN cord-001207-yjaiybwf 267 8 . . . cord-001207-yjaiybwf 267 9 toyoi toyoi NNP cord-001207-yjaiybwf 268 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 268 2 40112 40112 CD cord-001207-yjaiybwf 268 3 on on IN cord-001207-yjaiybwf 268 4 the the DT cord-001207-yjaiybwf 268 5 development development NN cord-001207-yjaiybwf 268 6 of of IN cord-001207-yjaiybwf 268 7 serum serum NN cord-001207-yjaiybwf 268 8 IgG IgG NNP cord-001207-yjaiybwf 268 9 and and CC cord-001207-yjaiybwf 268 10 faecal faecal JJ cord-001207-yjaiybwf 268 11 IgA IgA NNP cord-001207-yjaiybwf 268 12 of of IN cord-001207-yjaiybwf 268 13 sows sow NNS cord-001207-yjaiybwf 268 14 and and CC cord-001207-yjaiybwf 268 15 their -PRON- PRP$ cord-001207-yjaiybwf 268 16 piglets piglet NNS cord-001207-yjaiybwf 268 17 Influence influence NN cord-001207-yjaiybwf 268 18 of of IN cord-001207-yjaiybwf 268 19 a a DT cord-001207-yjaiybwf 268 20 probiotic probiotic JJ cord-001207-yjaiybwf 268 21 Enterococcus enterococcus NN cord-001207-yjaiybwf 268 22 faecium faecium NN cord-001207-yjaiybwf 269 1 strain strain VB cord-001207-yjaiybwf 269 2 on on IN cord-001207-yjaiybwf 269 3 development development NN cord-001207-yjaiybwf 269 4 of of IN cord-001207-yjaiybwf 269 5 the the DT cord-001207-yjaiybwf 269 6 immune immune JJ cord-001207-yjaiybwf 269 7 system system NN cord-001207-yjaiybwf 269 8 of of IN cord-001207-yjaiybwf 269 9 sows sow NNS cord-001207-yjaiybwf 269 10 and and CC cord-001207-yjaiybwf 269 11 piglets piglet NNS cord-001207-yjaiybwf 269 12 Modulatory modulatory JJ cord-001207-yjaiybwf 269 13 effects effect NNS cord-001207-yjaiybwf 269 14 of of IN cord-001207-yjaiybwf 269 15 Lactobacillus lactobacillus NN cord-001207-yjaiybwf 269 16 salivarius salivarius NN cord-001207-yjaiybwf 269 17 on on IN cord-001207-yjaiybwf 269 18 intestinal intestinal JJ cord-001207-yjaiybwf 269 19 mucosal mucosal JJ cord-001207-yjaiybwf 269 20 immunity immunity NN cord-001207-yjaiybwf 269 21 of of IN cord-001207-yjaiybwf 269 22 piglets piglet NNS cord-001207-yjaiybwf 270 1 Antiviral antiviral JJ cord-001207-yjaiybwf 270 2 effects effect NNS cord-001207-yjaiybwf 270 3 of of IN cord-001207-yjaiybwf 270 4 a a DT cord-001207-yjaiybwf 270 5 probiotic probiotic JJ cord-001207-yjaiybwf 270 6 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 270 7 faecium faecium NN cord-001207-yjaiybwf 270 8 strain strain NN cord-001207-yjaiybwf 270 9 against against IN cord-001207-yjaiybwf 270 10 transmissible transmissible JJ cord-001207-yjaiybwf 270 11 gastroenteritis gastroenteritis NN cord-001207-yjaiybwf 270 12 coronavirus coronavirus NN cord-001207-yjaiybwf 270 13 Influence influence NN cord-001207-yjaiybwf 270 14 of of IN cord-001207-yjaiybwf 270 15 age age NN cord-001207-yjaiybwf 270 16 and and CC cord-001207-yjaiybwf 270 17 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 270 18 faecium faecium NN cord-001207-yjaiybwf 271 1 NCIMB NCIMB NNP cord-001207-yjaiybwf 271 2 10415 10415 CD cord-001207-yjaiybwf 271 3 on on IN cord-001207-yjaiybwf 271 4 development development NN cord-001207-yjaiybwf 271 5 of of IN cord-001207-yjaiybwf 271 6 small small JJ cord-001207-yjaiybwf 271 7 intestinal intestinal JJ cord-001207-yjaiybwf 271 8 digestive digestive JJ cord-001207-yjaiybwf 271 9 physiology physiology NN cord-001207-yjaiybwf 271 10 in in IN cord-001207-yjaiybwf 271 11 piglets piglet NNS cord-001207-yjaiybwf 272 1 Individual individual JJ cord-001207-yjaiybwf 272 2 response response NN cord-001207-yjaiybwf 272 3 of of IN cord-001207-yjaiybwf 272 4 mother mother NN cord-001207-yjaiybwf 272 5 sows sow VBZ cord-001207-yjaiybwf 272 6 to to IN cord-001207-yjaiybwf 272 7 a a DT cord-001207-yjaiybwf 272 8 probiotic probiotic JJ cord-001207-yjaiybwf 272 9 E. E. NNP cord-001207-yjaiybwf 272 10 faecium faecium NN cord-001207-yjaiybwf 272 11 strain strain NN cord-001207-yjaiybwf 272 12 lead lead NN cord-001207-yjaiybwf 272 13 to to IN cord-001207-yjaiybwf 272 14 different different JJ cord-001207-yjaiybwf 272 15 microbiota microbiota NN cord-001207-yjaiybwf 272 16 composition composition NN cord-001207-yjaiybwf 272 17 in in IN cord-001207-yjaiybwf 272 18 their -PRON- PRP$ cord-001207-yjaiybwf 272 19 offspring offspring NN cord-001207-yjaiybwf 273 1 accepted accept VBN cord-001207-yjaiybwf 273 2 but but CC cord-001207-yjaiybwf 273 3 unpublished unpublished JJ cord-001207-yjaiybwf 273 4 so so RB cord-001207-yjaiybwf 273 5 far far JJ cord-001207-yjaiybwf 273 6 Effect effect NN cord-001207-yjaiybwf 273 7 of of IN cord-001207-yjaiybwf 273 8 the the DT cord-001207-yjaiybwf 273 9 probiotic probiotic JJ cord-001207-yjaiybwf 273 10 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 273 11 faecium faecium VBP cord-001207-yjaiybwf 273 12 NCIMB10415 ncimb10415 NN cord-001207-yjaiybwf 273 13 on on IN cord-001207-yjaiybwf 273 14 cell cell NN cord-001207-yjaiybwf 273 15 numbers number NNS cord-001207-yjaiybwf 273 16 of of IN cord-001207-yjaiybwf 273 17 total total JJ cord-001207-yjaiybwf 273 18 Enterococcus Enterococcus NNP cord-001207-yjaiybwf 273 19 spp spp NNS cord-001207-yjaiybwf 273 20 . . . cord-001207-yjaiybwf 274 1 , , , cord-001207-yjaiybwf 274 2 E. E. NNP cord-001207-yjaiybwf 274 3 faecium faecium NNP cord-001207-yjaiybwf 274 4 and and CC cord-001207-yjaiybwf 274 5 E. E. NNP cord-001207-yjaiybwf 274 6 faecalis faecalis NNP cord-001207-yjaiybwf 274 7 in in IN cord-001207-yjaiybwf 274 8 the the DT cord-001207-yjaiybwf 274 9 intestine intestine NN cord-001207-yjaiybwf 274 10 of of IN cord-001207-yjaiybwf 274 11 piglets piglet NNS cord-001207-yjaiybwf 275 1 Laboratory laboratory NN cord-001207-yjaiybwf 275 2 procedures procedure NNS cord-001207-yjaiybwf 275 3 to to TO cord-001207-yjaiybwf 275 4 generate generate VB cord-001207-yjaiybwf 275 5 viral viral JJ cord-001207-yjaiybwf 275 6 metagenomes metagenomes NNP cord-001207-yjaiybwf 275 7 Assembly assembly NN cord-001207-yjaiybwf 275 8 algorithms algorithm NNS cord-001207-yjaiybwf 275 9 for for IN cord-001207-yjaiybwf 275 10 next next JJ cord-001207-yjaiybwf 275 11 - - HYPH cord-001207-yjaiybwf 275 12 generation generation NN cord-001207-yjaiybwf 275 13 sequencing sequencing NN cord-001207-yjaiybwf 275 14 data datum NNS cord-001207-yjaiybwf 275 15 Basic Basic NNP cord-001207-yjaiybwf 275 16 Local Local NNP cord-001207-yjaiybwf 275 17 Alignment Alignment NNP cord-001207-yjaiybwf 275 18 Search Search NNP cord-001207-yjaiybwf 275 19 Tool Tool NNP cord-001207-yjaiybwf 275 20 Langmead Langmead NNP cord-001207-yjaiybwf 275 21 B B NNP cord-001207-yjaiybwf 275 22 , , , cord-001207-yjaiybwf 275 23 Salzberg Salzberg NNP cord-001207-yjaiybwf 275 24 SL SL NNP cord-001207-yjaiybwf 275 25 ( ( -LRB- cord-001207-yjaiybwf 275 26 2012 2012 CD cord-001207-yjaiybwf 275 27 ) ) -RRB- cord-001207-yjaiybwf 276 1 Fast fast JJ cord-001207-yjaiybwf 276 2 gapped gap VBN cord-001207-yjaiybwf 276 3 - - HYPH cord-001207-yjaiybwf 276 4 read read VBN cord-001207-yjaiybwf 276 5 alignment alignment NN cord-001207-yjaiybwf 276 6 with with IN cord-001207-yjaiybwf 276 7 Bowtie Bowtie NNP cord-001207-yjaiybwf 276 8 2 2 CD cord-001207-yjaiybwf 277 1 A a DT cord-001207-yjaiybwf 277 2 mathematical mathematical JJ cord-001207-yjaiybwf 277 3 theory theory NN cord-001207-yjaiybwf 277 4 of of IN cord-001207-yjaiybwf 277 5 communication communication NN cord-001207-yjaiybwf 277 6 An an DT cord-001207-yjaiybwf 277 7 Ordination Ordination NNP cord-001207-yjaiybwf 277 8 of of IN cord-001207-yjaiybwf 277 9 the the DT cord-001207-yjaiybwf 277 10 Upland Upland NNP cord-001207-yjaiybwf 277 11 Forest Forest NNP cord-001207-yjaiybwf 277 12 Communities Communities NNPS cord-001207-yjaiybwf 277 13 of of IN cord-001207-yjaiybwf 277 14 Southern Southern NNP cord-001207-yjaiybwf 277 15 Wisconsin Wisconsin NNP cord-001207-yjaiybwf 277 16 Metagenomic Metagenomic NNP cord-001207-yjaiybwf 277 17 study study NN cord-001207-yjaiybwf 277 18 of of IN cord-001207-yjaiybwf 277 19 the the DT cord-001207-yjaiybwf 277 20 viruses virus NNS cord-001207-yjaiybwf 277 21 of of IN cord-001207-yjaiybwf 277 22 African african JJ cord-001207-yjaiybwf 277 23 straw straw NN cord-001207-yjaiybwf 277 24 - - HYPH cord-001207-yjaiybwf 277 25 coloured colour VBN cord-001207-yjaiybwf 277 26 fruit fruit NN cord-001207-yjaiybwf 277 27 bats bat NNS cord-001207-yjaiybwf 277 28 : : : cord-001207-yjaiybwf 277 29 detection detection NN cord-001207-yjaiybwf 277 30 of of IN cord-001207-yjaiybwf 277 31 a a DT cord-001207-yjaiybwf 277 32 chiropteran chiropteran JJ cord-001207-yjaiybwf 277 33 poxvirus poxvirus NNP cord-001207-yjaiybwf 277 34 and and CC cord-001207-yjaiybwf 277 35 isolation isolation NN cord-001207-yjaiybwf 277 36 of of IN cord-001207-yjaiybwf 277 37 a a DT cord-001207-yjaiybwf 277 38 novel novel JJ cord-001207-yjaiybwf 277 39 adenovirus adenovirus NN cord-001207-yjaiybwf 277 40 Candidate candidate NN cord-001207-yjaiybwf 277 41 new new JJ cord-001207-yjaiybwf 277 42 species specie NNS cord-001207-yjaiybwf 277 43 of of IN cord-001207-yjaiybwf 277 44 Kobuvirus Kobuvirus NNP cord-001207-yjaiybwf 277 45 in in IN cord-001207-yjaiybwf 277 46 porcine porcine JJ cord-001207-yjaiybwf 277 47 hosts host NNS cord-001207-yjaiybwf 277 48 Characterization characterization NN cord-001207-yjaiybwf 277 49 of of IN cord-001207-yjaiybwf 277 50 1706 1706 CD cord-001207-yjaiybwf 277 51 , , , cord-001207-yjaiybwf 277 52 a a DT cord-001207-yjaiybwf 277 53 virulent virulent JJ cord-001207-yjaiybwf 277 54 phage phage NN cord-001207-yjaiybwf 277 55 from from IN cord-001207-yjaiybwf 277 56 Lactococcus Lactococcus NNP cord-001207-yjaiybwf 277 57 lactis lactis NN cord-001207-yjaiybwf 277 58 with with IN cord-001207-yjaiybwf 277 59 similarities similarity NNS cord-001207-yjaiybwf 277 60 to to IN cord-001207-yjaiybwf 277 61 prophages prophage NNS cord-001207-yjaiybwf 277 62 from from IN cord-001207-yjaiybwf 277 63 other other JJ cord-001207-yjaiybwf 277 64 Firmicutes Firmicutes NNPS cord-001207-yjaiybwf 277 65 Diverse diverse JJ cord-001207-yjaiybwf 278 1 circular circular JJ cord-001207-yjaiybwf 278 2 ssDNA ssdna JJ cord-001207-yjaiybwf 278 3 viruses virus NNS cord-001207-yjaiybwf 278 4 discovered discover VBN cord-001207-yjaiybwf 278 5 in in IN cord-001207-yjaiybwf 278 6 dragonflies dragonfly NNS cord-001207-yjaiybwf 278 7 ( ( -LRB- cord-001207-yjaiybwf 278 8 Odonata Odonata NNS cord-001207-yjaiybwf 278 9 : : : cord-001207-yjaiybwf 278 10 Epiprocta Epiprocta NNP cord-001207-yjaiybwf 278 11 ) ) -RRB- cord-001207-yjaiybwf 279 1 We -PRON- PRP cord-001207-yjaiybwf 279 2 thank thank VBP cord-001207-yjaiybwf 279 3 Robert Robert NNP cord-001207-yjaiybwf 279 4 Pieper Pieper NNP cord-001207-yjaiybwf 279 5 and and CC cord-001207-yjaiybwf 279 6 his -PRON- PRP$ cord-001207-yjaiybwf 279 7 colleagues colleague NNS cord-001207-yjaiybwf 279 8 at at IN cord-001207-yjaiybwf 279 9 the the DT cord-001207-yjaiybwf 279 10 Institute Institute NNP cord-001207-yjaiybwf 279 11 for for IN cord-001207-yjaiybwf 279 12 Animal Animal NNP cord-001207-yjaiybwf 279 13 Nutrition Nutrition NNP cord-001207-yjaiybwf 279 14 ( ( -LRB- cord-001207-yjaiybwf 279 15 Free Free NNP cord-001207-yjaiybwf 279 16 University University NNP cord-001207-yjaiybwf 279 17 Berlin Berlin NNP cord-001207-yjaiybwf 279 18 , , , cord-001207-yjaiybwf 279 19 Germany Germany NNP cord-001207-yjaiybwf 279 20 ) ) -RRB- cord-001207-yjaiybwf 279 21 for for IN cord-001207-yjaiybwf 279 22 the the DT cord-001207-yjaiybwf 279 23 coordination coordination NN cord-001207-yjaiybwf 279 24 of of IN cord-001207-yjaiybwf 279 25 the the DT cord-001207-yjaiybwf 279 26 animal animal NN cord-001207-yjaiybwf 279 27 experiment experiment NN cord-001207-yjaiybwf 279 28 and and CC cord-001207-yjaiybwf 279 29 Paul Paul NNP cord-001207-yjaiybwf 279 30 Wrede Wrede NNP cord-001207-yjaiybwf 279 31 ( ( -LRB- cord-001207-yjaiybwf 279 32 Charité Charité NNP cord-001207-yjaiybwf 279 33 , , , cord-001207-yjaiybwf 279 34 Berlin Berlin NNP cord-001207-yjaiybwf 279 35 , , , cord-001207-yjaiybwf 279 36 Germany Germany NNP cord-001207-yjaiybwf 279 37 ) ) -RRB- cord-001207-yjaiybwf 279 38 for for IN cord-001207-yjaiybwf 279 39 helpful helpful JJ cord-001207-yjaiybwf 279 40 discussion discussion NN cord-001207-yjaiybwf 279 41 . . . cord-001207-yjaiybwf 280 1 We -PRON- PRP cord-001207-yjaiybwf 280 2 also also RB cord-001207-yjaiybwf 280 3 thank thank VBP cord-001207-yjaiybwf 280 4 Wilfried Wilfried NNP cord-001207-yjaiybwf 280 5 Vahjen Vahjen NNP cord-001207-yjaiybwf 280 6 and and CC cord-001207-yjaiybwf 280 7 Ingo Ingo NNP cord-001207-yjaiybwf 280 8 Starke Starke NNP cord-001207-yjaiybwf 280 9 ( ( -LRB- cord-001207-yjaiybwf 280 10 Institute Institute NNP cord-001207-yjaiybwf 280 11 for for IN cord-001207-yjaiybwf 280 12 Animal Animal NNP cord-001207-yjaiybwf 280 13 Nutrition Nutrition NNP cord-001207-yjaiybwf 280 14 , , , cord-001207-yjaiybwf 280 15 Free Free NNP cord-001207-yjaiybwf 280 16 University University NNP cord-001207-yjaiybwf 280 17 Berlin Berlin NNP cord-001207-yjaiybwf 280 18 , , , cord-001207-yjaiybwf 280 19 Germany Germany NNP cord-001207-yjaiybwf 280 20 ) ) -RRB- cord-001207-yjaiybwf 280 21 for for IN cord-001207-yjaiybwf 280 22 their -PRON- PRP$ cord-001207-yjaiybwf 280 23 support support NN cord-001207-yjaiybwf 280 24 in in IN cord-001207-yjaiybwf 280 25 detection detection NN cord-001207-yjaiybwf 280 26 of of IN cord-001207-yjaiybwf 280 27 E. E. NNP cord-001207-yjaiybwf 280 28 faecium faecium NN cord-001207-yjaiybwf 280 29 NCIMB NCIMB NNP cord-001207-yjaiybwf 280 30 10415 10415 CD cord-001207-yjaiybwf 280 31 in in IN cord-001207-yjaiybwf 280 32 the the DT cord-001207-yjaiybwf 280 33 samples sample NNS cord-001207-yjaiybwf 280 34 . . . cord-001207-yjaiybwf 280 35 _SP