id author title date pages extension mime words sentences flesch summary cache txt cord-344131-e7phs0jd Ford, Richard B. Section 4 Diagnostic and Therapeutic Procedures 2012-12-31 .txt text/plain 40123 2277 51 Before actually collecting and submitting a sample to a laboratory for bacterial culture, it is appropriate (whenever feasible to do so) to prepare, stain, and examine, under direct microscopy, exudates or fluid from the suspect material or tissue. Fine-needle aspiration, the use of needle and syringe to remove cells from normal and abnormal tissue, apply them to a glass slide, stain the smear, and review the results immediately is among the most useful, cost-effective procedures available in clinical practice. Do not remove the syringe from the tissue while maintaining negative pressure, because this can Enlargement of nucleus or nuclei larger than 10 nm Decreased nuclear/cytoplasmic ratio Multinucleation because of abnormal mitosis Abnormal or frequent mitosis Variations in size and shape of nuclei Increase in size and number of nucleoli Increased basophilia of cellular cytoplasm; increased RNA content Anisokaryosis or pleomorphism Multinucleated giant cells box 4-4 cytologic feAtuRes of mAlignAncy 4 result in the aspiration of significant amounts of blood from the skin, thereby significantly diluting the sample with peripheral blood. ./cache/cord-344131-e7phs0jd.txt ./txt/cord-344131-e7phs0jd.txt