id author title date pages extension mime words sentences flesch summary cache txt cord-323973-wszo9s3d Zhu, Hanliang The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond 2020-07-20 .txt text/plain 9784 493 50 [9] The analysis of larger volumes of biological fluids with a low viral load is likely to reduce the risk of false-negative results, but microfluidic point-of-care (POC) devices are typically unable to handle mL-scale volumes in a short time due to the requirement of slow flow rates. [15] The PCR test on samples prepared from blood and urine specimens is capable of detecting the virus in the early stages of the disease, resulting in early diagnosis and subsequent isolation of infected patients to block transmission. The total reaction time depends on a series of parameters, such as the chip size, the PCR master mix volume determining the value of C, the thermal conductivity of the substrate (G), and the temperature cycling rate. A number of fully integrated systems have so far been developed, starting with the non-portable GenExpert from Cepheid, which was first utilized for anthrax detection by the United States Postal Service, [64] and then with different primers to perform HIV and tuberculosis diagnostics in South Africa. ./cache/cord-323973-wszo9s3d.txt ./txt/cord-323973-wszo9s3d.txt