id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-281916-v6u5mr2i	Bonnin, Paul	Study and interest of cellular load in respiratory samples for the optimization of molecular virological diagnosis in clinical practice	2016-08-09		.txt	text/plain	4124	229	46	METHODS: Our study included 800 upper respiratory tract specimens of which 400 negative and 400 positive for viral detection in multiplex PCR. If a rich cell collection appears to be an important prerequisite for the quality of respiratory viral diagnosis, there is currently no information on a possible cellularity threshold that would validate the result of the viral molecular detection. These 800 aliquots were selected in the laboratory samples bank according to their results in virological diagnosis: 400 Positive and 400 Negative for molecular detection of respiratory panel using the RespiFinder ® Smart_22_Fast technique (Pathofinder, Maastricht, Netherlands). The main objectives of this work have been to study the cellularity of these clinical respiratory specimens, to propose a possible definition of what is commonly called "cellular richness," and to measure the impact of this marker on the molecular viral diagnosis. (2014) performed a molecular cell quantification using real time PCR in order to validate viral detection on nasal swabs.	./cache/cord-281916-v6u5mr2i.txt	./txt/cord-281916-v6u5mr2i.txt