id	sid	tid	token	lemma	pos
cord-271972-qhr6iir6	1	1	key	key	JJ
cord-271972-qhr6iir6	2	1	:	:	:
cord-271972-qhr6iir6	2	2	cord-271972-qhr6iir6	cord-271972-qhr6iir6	NN
cord-271972-qhr6iir6	2	3	authors	author	NNS
cord-271972-qhr6iir6	2	4	:	:	:
cord-271972-qhr6iir6	2	5	Gaglia	Gaglia	NNP
cord-271972-qhr6iir6	2	6	,	,	,
cord-271972-qhr6iir6	2	7	Marta	Marta	NNP
cord-271972-qhr6iir6	2	8	Maria	Maria	NNP
cord-271972-qhr6iir6	2	9	;	;	:
cord-271972-qhr6iir6	2	10	Glaunsinger	Glaunsinger	NNP
cord-271972-qhr6iir6	2	11	,	,	,
cord-271972-qhr6iir6	2	12	Britt	Britt	NNP
cord-271972-qhr6iir6	2	13	A.	a.	NN
cord-271972-qhr6iir6	2	14	title	title	NN
cord-271972-qhr6iir6	2	15	:	:	:
cord-271972-qhr6iir6	2	16	Viruses	virus	NNS
cord-271972-qhr6iir6	2	17	and	and	CC
cord-271972-qhr6iir6	2	18	the	the	DT
cord-271972-qhr6iir6	2	19	cellular	cellular	JJ
cord-271972-qhr6iir6	2	20	RNA	RNA	NNP
cord-271972-qhr6iir6	2	21	decay	decay	NN
cord-271972-qhr6iir6	2	22	machinery	machinery	NN
cord-271972-qhr6iir6	2	23	date	date	NN
cord-271972-qhr6iir6	2	24	:	:	:
cord-271972-qhr6iir6	3	1	2010	2010	CD
cord-271972-qhr6iir6	3	2	-	-	SYM
cord-271972-qhr6iir6	3	3	05	05	CD
cord-271972-qhr6iir6	3	4	-	-	HYPH
cord-271972-qhr6iir6	3	5	06	06	CD
cord-271972-qhr6iir6	3	6	journal	journal	NN
cord-271972-qhr6iir6	3	7	:	:	:
cord-271972-qhr6iir6	4	1	Wiley	Wiley	NNP
cord-271972-qhr6iir6	4	2	Interdiscip	Interdiscip	NNP
cord-271972-qhr6iir6	4	3	Rev	Rev	NNP
cord-271972-qhr6iir6	4	4	RNA	RNA	NNP
cord-271972-qhr6iir6	4	5	DOI	DOI	NNP
cord-271972-qhr6iir6	4	6	:	:	:
cord-271972-qhr6iir6	5	1	10.1002	10.1002	CD
cord-271972-qhr6iir6	5	2	/	/	SYM
cord-271972-qhr6iir6	5	3	wrna.3	wrna.3	NNP
cord-271972-qhr6iir6	5	4	sha	sha	NNP
cord-271972-qhr6iir6	5	5	:	:	:
cord-271972-qhr6iir6	5	6	3a0f299c427b6bc9ad7be9dc0aa9d5a12ec7880e	3a0f299c427b6bc9ad7be9dc0aa9d5a12ec7880e	CD
cord-271972-qhr6iir6	5	7	doc_id	doc_id	CD
cord-271972-qhr6iir6	5	8	:	:	:
cord-271972-qhr6iir6	5	9	271972	271972	CD
cord-271972-qhr6iir6	5	10	cord_uid	cord_uid	NNS
cord-271972-qhr6iir6	5	11	:	:	:
cord-271972-qhr6iir6	5	12	qhr6iir6	qhr6iir6	NNP
cord-271972-qhr6iir6	6	1	The	the	DT
cord-271972-qhr6iir6	6	2	ability	ability	NN
cord-271972-qhr6iir6	6	3	to	to	TO
cord-271972-qhr6iir6	6	4	control	control	VB
cord-271972-qhr6iir6	6	5	cellular	cellular	JJ
cord-271972-qhr6iir6	6	6	and	and	CC
cord-271972-qhr6iir6	6	7	viral	viral	JJ
cord-271972-qhr6iir6	6	8	gene	gene	NN
cord-271972-qhr6iir6	6	9	expression	expression	NN
cord-271972-qhr6iir6	6	10	,	,	,
cord-271972-qhr6iir6	6	11	either	either	CC
cord-271972-qhr6iir6	6	12	globally	globally	RB
cord-271972-qhr6iir6	6	13	or	or	CC
cord-271972-qhr6iir6	6	14	selectively	selectively	RB
cord-271972-qhr6iir6	6	15	,	,	,
cord-271972-qhr6iir6	6	16	is	be	VBZ
cord-271972-qhr6iir6	6	17	central	central	JJ
cord-271972-qhr6iir6	6	18	to	to	IN
cord-271972-qhr6iir6	6	19	a	a	DT
cord-271972-qhr6iir6	6	20	successful	successful	JJ
cord-271972-qhr6iir6	6	21	viral	viral	JJ
cord-271972-qhr6iir6	6	22	infection	infection	NN
cord-271972-qhr6iir6	6	23	,	,	,
cord-271972-qhr6iir6	6	24	and	and	CC
cord-271972-qhr6iir6	6	25	it	-PRON-	PRP
cord-271972-qhr6iir6	6	26	is	be	VBZ
cord-271972-qhr6iir6	6	27	also	also	RB
cord-271972-qhr6iir6	6	28	crucial	crucial	JJ
cord-271972-qhr6iir6	6	29	for	for	IN
cord-271972-qhr6iir6	6	30	the	the	DT
cord-271972-qhr6iir6	6	31	host	host	NN
cord-271972-qhr6iir6	6	32	to	to	TO
cord-271972-qhr6iir6	6	33	respond	respond	VB
cord-271972-qhr6iir6	6	34	and	and	CC
cord-271972-qhr6iir6	6	35	eradicate	eradicate	VB
cord-271972-qhr6iir6	6	36	pathogens	pathogen	NNS
cord-271972-qhr6iir6	6	37	.	.	.
cord-271972-qhr6iir6	7	1	In	in	IN
cord-271972-qhr6iir6	7	2	eukaryotes	eukaryote	NNS
cord-271972-qhr6iir6	7	3	,	,	,
cord-271972-qhr6iir6	7	4	regulation	regulation	NN
cord-271972-qhr6iir6	7	5	of	of	IN
cord-271972-qhr6iir6	7	6	message	message	NN
cord-271972-qhr6iir6	7	7	stability	stability	NN
cord-271972-qhr6iir6	7	8	contributes	contribute	VBZ
cord-271972-qhr6iir6	7	9	significantly	significantly	RB
cord-271972-qhr6iir6	7	10	to	to	IN
cord-271972-qhr6iir6	7	11	the	the	DT
cord-271972-qhr6iir6	7	12	control	control	NN
cord-271972-qhr6iir6	7	13	of	of	IN
cord-271972-qhr6iir6	7	14	gene	gene	NN
cord-271972-qhr6iir6	7	15	expression	expression	NN
cord-271972-qhr6iir6	7	16	and	and	CC
cord-271972-qhr6iir6	7	17	plays	play	VBZ
cord-271972-qhr6iir6	7	18	a	a	DT
cord-271972-qhr6iir6	7	19	prominent	prominent	JJ
cord-271972-qhr6iir6	7	20	role	role	NN
cord-271972-qhr6iir6	7	21	in	in	IN
cord-271972-qhr6iir6	7	22	the	the	DT
cord-271972-qhr6iir6	7	23	normal	normal	JJ
cord-271972-qhr6iir6	7	24	physiology	physiology	NN
cord-271972-qhr6iir6	7	25	of	of	IN
cord-271972-qhr6iir6	7	26	a	a	DT
cord-271972-qhr6iir6	7	27	cell	cell	NN
cord-271972-qhr6iir6	7	28	as	as	RB
cord-271972-qhr6iir6	7	29	well	well	RB
cord-271972-qhr6iir6	7	30	as	as	IN
cord-271972-qhr6iir6	7	31	in	in	IN
cord-271972-qhr6iir6	7	32	its	-PRON-	PRP$
cord-271972-qhr6iir6	7	33	response	response	NN
cord-271972-qhr6iir6	7	34	to	to	IN
cord-271972-qhr6iir6	7	35	environmental	environmental	JJ
cord-271972-qhr6iir6	7	36	and	and	CC
cord-271972-qhr6iir6	7	37	pathogenic	pathogenic	JJ
cord-271972-qhr6iir6	7	38	stresses	stress	NNS
cord-271972-qhr6iir6	7	39	.	.	.
cord-271972-qhr6iir6	8	1	Not	not	RB
cord-271972-qhr6iir6	8	2	surprisingly	surprisingly	RB
cord-271972-qhr6iir6	8	3	,	,	,
cord-271972-qhr6iir6	8	4	emerging	emerge	VBG
cord-271972-qhr6iir6	8	5	evidence	evidence	NN
cord-271972-qhr6iir6	8	6	indicates	indicate	VBZ
cord-271972-qhr6iir6	8	7	that	that	IN
cord-271972-qhr6iir6	8	8	there	there	EX
cord-271972-qhr6iir6	8	9	are	be	VBP
cord-271972-qhr6iir6	8	10	significant	significant	JJ
cord-271972-qhr6iir6	8	11	interactions	interaction	NNS
cord-271972-qhr6iir6	8	12	between	between	IN
cord-271972-qhr6iir6	8	13	the	the	DT
cord-271972-qhr6iir6	8	14	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	8	15	RNA	RNA	NNP
cord-271972-qhr6iir6	8	16	turnover	turnover	NN
cord-271972-qhr6iir6	8	17	machinery	machinery	NN
cord-271972-qhr6iir6	8	18	and	and	CC
cord-271972-qhr6iir6	8	19	a	a	DT
cord-271972-qhr6iir6	8	20	wide	wide	JJ
cord-271972-qhr6iir6	8	21	variety	variety	NN
cord-271972-qhr6iir6	8	22	of	of	IN
cord-271972-qhr6iir6	8	23	viruses	virus	NNS
cord-271972-qhr6iir6	8	24	.	.	.
cord-271972-qhr6iir6	9	1	Interestingly	interestingly	RB
cord-271972-qhr6iir6	9	2	,	,	,
cord-271972-qhr6iir6	9	3	in	in	IN
cord-271972-qhr6iir6	9	4	many	many	JJ
cord-271972-qhr6iir6	9	5	cases	case	NNS
cord-271972-qhr6iir6	9	6	viruses	virus	NNS
cord-271972-qhr6iir6	9	7	have	have	VBP
cord-271972-qhr6iir6	9	8	evolved	evolve	VBN
cord-271972-qhr6iir6	9	9	mechanisms	mechanism	NNS
cord-271972-qhr6iir6	9	10	not	not	RB
cord-271972-qhr6iir6	9	11	only	only	RB
cord-271972-qhr6iir6	9	12	to	to	TO
cord-271972-qhr6iir6	9	13	evade	evade	VB
cord-271972-qhr6iir6	9	14	eradication	eradication	NN
cord-271972-qhr6iir6	9	15	by	by	IN
cord-271972-qhr6iir6	9	16	these	these	DT
cord-271972-qhr6iir6	9	17	pathways	pathway	NNS
cord-271972-qhr6iir6	9	18	,	,	,
cord-271972-qhr6iir6	9	19	but	but	CC
cord-271972-qhr6iir6	9	20	also	also	RB
cord-271972-qhr6iir6	9	21	to	to	TO
cord-271972-qhr6iir6	9	22	manipulate	manipulate	VB
cord-271972-qhr6iir6	9	23	them	-PRON-	PRP
cord-271972-qhr6iir6	9	24	for	for	IN
cord-271972-qhr6iir6	9	25	enhanced	enhance	VBN
cord-271972-qhr6iir6	9	26	viral	viral	JJ
cord-271972-qhr6iir6	9	27	replication	replication	NN
cord-271972-qhr6iir6	9	28	and	and	CC
cord-271972-qhr6iir6	9	29	gene	gene	NN
cord-271972-qhr6iir6	9	30	expression	expression	NN
cord-271972-qhr6iir6	9	31	.	.	.
cord-271972-qhr6iir6	10	1	Given	give	VBN
cord-271972-qhr6iir6	10	2	our	-PRON-	PRP$
cord-271972-qhr6iir6	10	3	incomplete	incomplete	JJ
cord-271972-qhr6iir6	10	4	understanding	understanding	NN
cord-271972-qhr6iir6	10	5	of	of	IN
cord-271972-qhr6iir6	10	6	how	how	WRB
cord-271972-qhr6iir6	10	7	many	many	JJ
cord-271972-qhr6iir6	10	8	of	of	IN
cord-271972-qhr6iir6	10	9	these	these	DT
cord-271972-qhr6iir6	10	10	pathways	pathway	NNS
cord-271972-qhr6iir6	10	11	are	be	VBP
cord-271972-qhr6iir6	10	12	normally	normally	RB
cord-271972-qhr6iir6	10	13	regulated	regulate	VBN
cord-271972-qhr6iir6	10	14	,	,	,
cord-271972-qhr6iir6	10	15	viruses	virus	NNS
cord-271972-qhr6iir6	10	16	should	should	MD
cord-271972-qhr6iir6	10	17	be	be	VB
cord-271972-qhr6iir6	10	18	powerful	powerful	JJ
cord-271972-qhr6iir6	10	19	tools	tool	NNS
cord-271972-qhr6iir6	10	20	to	to	TO
cord-271972-qhr6iir6	10	21	help	help	VB
cord-271972-qhr6iir6	10	22	deconstruct	deconstruct	VB
cord-271972-qhr6iir6	10	23	the	the	DT
cord-271972-qhr6iir6	10	24	complex	complex	JJ
cord-271972-qhr6iir6	10	25	networks	network	NNS
cord-271972-qhr6iir6	10	26	and	and	CC
cord-271972-qhr6iir6	10	27	events	event	NNS
cord-271972-qhr6iir6	10	28	governing	govern	VBG
cord-271972-qhr6iir6	10	29	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	10	30	RNA	RNA	NNP
cord-271972-qhr6iir6	10	31	stability	stability	NN
cord-271972-qhr6iir6	10	32	.	.	.
cord-271972-qhr6iir6	11	1	Copyright	copyright	NN
cord-271972-qhr6iir6	11	2	©	©	NNP
cord-271972-qhr6iir6	11	3	2010	2010	CD
cord-271972-qhr6iir6	11	4	John	John	NNP
cord-271972-qhr6iir6	11	5	Wiley	Wiley	NNP
cord-271972-qhr6iir6	11	6	&	&	CC
cord-271972-qhr6iir6	11	7	Sons	Sons	NNPS
cord-271972-qhr6iir6	11	8	,	,	,
cord-271972-qhr6iir6	11	9	Ltd.	Ltd.	NNP
cord-271972-qhr6iir6	11	10	1	1	CD
cord-271972-qhr6iir6	11	11	..	..	.
cord-271972-qhr6iir6	12	1	RNA	RNA	NNP
cord-271972-qhr6iir6	12	2	Turnover	Turnover	NNP
cord-271972-qhr6iir6	12	3	and	and	CC
cord-271972-qhr6iir6	12	4	Surveillance	surveillance	NN
cord-271972-qhr6iir6	13	1	>	>	XX
cord-271972-qhr6iir6	14	1	Turnover	turnover	NN
cord-271972-qhr6iir6	14	2	/	/	SYM
cord-271972-qhr6iir6	14	3	Surveillance	Surveillance	NNP
cord-271972-qhr6iir6	14	4	Mechanisms	Mechanisms	NNPS
cord-271972-qhr6iir6	14	5	;	;	:
cord-271972-qhr6iir6	15	1	2	2	LS
cord-271972-qhr6iir6	15	2	..	..	NFP
cord-271972-qhr6iir6	15	3	RNA	RNA	NNP
cord-271972-qhr6iir6	15	4	in	in	IN
cord-271972-qhr6iir6	15	5	Disease	Disease	NNP
cord-271972-qhr6iir6	15	6	and	and	CC
cord-271972-qhr6iir6	15	7	Development	Development	NNP
cord-271972-qhr6iir6	16	1	>	>	XX
cord-271972-qhr6iir6	17	1	RNA	RNA	NNP
cord-271972-qhr6iir6	17	2	in	in	IN
cord-271972-qhr6iir6	17	3	Disease	Disease	NNP
cord-271972-qhr6iir6	17	4	.	.	.
cord-271972-qhr6iir6	18	1	T	T	NNP
cord-271972-qhr6iir6	18	2	he	-PRON-	PRP
cord-271972-qhr6iir6	18	3	virus	virus	NN
cord-271972-qhr6iir6	18	4	-	-	HYPH
cord-271972-qhr6iir6	18	5	host	host	NN
cord-271972-qhr6iir6	18	6	interaction	interaction	NN
cord-271972-qhr6iir6	18	7	is	be	VBZ
cord-271972-qhr6iir6	18	8	akin	akin	JJ
cord-271972-qhr6iir6	18	9	to	to	IN
cord-271972-qhr6iir6	18	10	an	an	DT
cord-271972-qhr6iir6	18	11	evolutionary	evolutionary	JJ
cord-271972-qhr6iir6	18	12	arms	arm	NNS
cord-271972-qhr6iir6	18	13	race	race	NN
cord-271972-qhr6iir6	18	14	;	;	:
cord-271972-qhr6iir6	18	15	viruses	virus	NNS
cord-271972-qhr6iir6	18	16	continually	continually	RB
cord-271972-qhr6iir6	18	17	evolve	evolve	VBP
cord-271972-qhr6iir6	18	18	and	and	CC
cord-271972-qhr6iir6	18	19	finetune	finetune	VB
cord-271972-qhr6iir6	18	20	mechanisms	mechanism	NNS
cord-271972-qhr6iir6	18	21	to	to	TO
cord-271972-qhr6iir6	18	22	exploit	exploit	VB
cord-271972-qhr6iir6	18	23	the	the	DT
cord-271972-qhr6iir6	18	24	cellular	cellular	JJ
cord-271972-qhr6iir6	18	25	machinery	machinery	NN
cord-271972-qhr6iir6	18	26	for	for	IN
cord-271972-qhr6iir6	18	27	their	-PRON-	PRP$
cord-271972-qhr6iir6	18	28	own	own	JJ
cord-271972-qhr6iir6	18	29	replication	replication	NN
cord-271972-qhr6iir6	18	30	,	,	,
cord-271972-qhr6iir6	18	31	while	while	IN
cord-271972-qhr6iir6	18	32	the	the	DT
cord-271972-qhr6iir6	18	33	host	host	NN
cord-271972-qhr6iir6	18	34	counter	counter	NN
cord-271972-qhr6iir6	18	35	-	-	NNS
cord-271972-qhr6iir6	18	36	attacks	attack	NNS
cord-271972-qhr6iir6	18	37	using	use	VBG
cord-271972-qhr6iir6	18	38	a	a	DT
cord-271972-qhr6iir6	18	39	multitude	multitude	NN
cord-271972-qhr6iir6	18	40	of	of	IN
cord-271972-qhr6iir6	18	41	strategies	strategy	NNS
cord-271972-qhr6iir6	18	42	to	to	TO
cord-271972-qhr6iir6	18	43	detect	detect	VB
cord-271972-qhr6iir6	18	44	and	and	CC
cord-271972-qhr6iir6	18	45	destroy	destroy	VB
cord-271972-qhr6iir6	18	46	foreign	foreign	JJ
cord-271972-qhr6iir6	18	47	invaders	invader	NNS
cord-271972-qhr6iir6	18	48	.	.	.
cord-271972-qhr6iir6	19	1	Many	many	JJ
cord-271972-qhr6iir6	19	2	such	such	JJ
cord-271972-qhr6iir6	19	3	'	'	``
cord-271972-qhr6iir6	19	4	molecular	molecular	JJ
cord-271972-qhr6iir6	19	5	battles	battle	NNS
cord-271972-qhr6iir6	19	6	'	'	POS
cord-271972-qhr6iir6	19	7	are	be	VBP
cord-271972-qhr6iir6	19	8	waged	wage	VBN
cord-271972-qhr6iir6	19	9	to	to	TO
cord-271972-qhr6iir6	19	10	control	control	VB
cord-271972-qhr6iir6	19	11	gene	gene	NN
cord-271972-qhr6iir6	19	12	expression	expression	NN
cord-271972-qhr6iir6	19	13	,	,	,
cord-271972-qhr6iir6	19	14	as	as	IN
cord-271972-qhr6iir6	19	15	commandeering	commandeer	VBG
cord-271972-qhr6iir6	19	16	this	this	DT
cord-271972-qhr6iir6	19	17	machinery	machinery	NN
cord-271972-qhr6iir6	19	18	is	be	VBZ
cord-271972-qhr6iir6	19	19	crucial	crucial	JJ
cord-271972-qhr6iir6	19	20	to	to	IN
cord-271972-qhr6iir6	19	21	the	the	DT
cord-271972-qhr6iir6	19	22	success	success	NN
cord-271972-qhr6iir6	19	23	of	of	IN
cord-271972-qhr6iir6	19	24	all	all	DT
cord-271972-qhr6iir6	19	25	viral	viral	JJ
cord-271972-qhr6iir6	19	26	infections	infection	NNS
cord-271972-qhr6iir6	19	27	.	.	.
cord-271972-qhr6iir6	20	1	Given	give	VBN
cord-271972-qhr6iir6	20	2	that	that	IN
cord-271972-qhr6iir6	20	3	the	the	DT
cord-271972-qhr6iir6	20	4	regulation	regulation	NN
cord-271972-qhr6iir6	20	5	of	of	IN
cord-271972-qhr6iir6	20	6	cellular	cellular	JJ
cord-271972-qhr6iir6	20	7	gene	gene	NN
cord-271972-qhr6iir6	20	8	expression	expression	NN
cord-271972-qhr6iir6	20	9	is	be	VBZ
cord-271972-qhr6iir6	20	10	orchestrated	orchestrate	VBN
cord-271972-qhr6iir6	20	11	in	in	IN
cord-271972-qhr6iir6	20	12	large	large	JJ
cord-271972-qhr6iir6	20	13	measure	measure	NN
cord-271972-qhr6iir6	20	14	by	by	IN
cord-271972-qhr6iir6	20	15	changes	change	NNS
cord-271972-qhr6iir6	20	16	in	in	IN
cord-271972-qhr6iir6	20	17	messenger	messenger	NN
cord-271972-qhr6iir6	20	18	RNA	RNA	NNP
cord-271972-qhr6iir6	20	19	(	(	-LRB-
cord-271972-qhr6iir6	20	20	mRNA	mrna	NN
cord-271972-qhr6iir6	20	21	)	)	-RRB-
cord-271972-qhr6iir6	20	22	stability	stability	NN
cord-271972-qhr6iir6	20	23	,	,	,
cord-271972-qhr6iir6	20	24	viruses	virus	NNS
cord-271972-qhr6iir6	20	25	must	must	MD
cord-271972-qhr6iir6	20	26	interface	interface	VB
cord-271972-qhr6iir6	20	27	with	with	IN
cord-271972-qhr6iir6	20	28	the	the	DT
cord-271972-qhr6iir6	20	29	cellular	cellular	JJ
cord-271972-qhr6iir6	20	30	RNA	RNA	NNP
cord-271972-qhr6iir6	20	31	decay	decay	NN
cord-271972-qhr6iir6	20	32	pathways	pathway	NNS
cord-271972-qhr6iir6	20	33	to	to	TO
cord-271972-qhr6iir6	20	34	control	control	VB
cord-271972-qhr6iir6	20	35	the	the	DT
cord-271972-qhr6iir6	20	36	levels	level	NNS
cord-271972-qhr6iir6	20	37	of	of	IN
cord-271972-qhr6iir6	20	38	cellular	cellular	JJ
cord-271972-qhr6iir6	20	39	and	and	CC
cord-271972-qhr6iir6	20	40	viral	viral	JJ
cord-271972-qhr6iir6	20	41	RNAs	rna	NNS
cord-271972-qhr6iir6	20	42	.	.	.
cord-271972-qhr6iir6	21	1	In	in	IN
cord-271972-qhr6iir6	21	2	addition	addition	NN
cord-271972-qhr6iir6	21	3	,	,	,
cord-271972-qhr6iir6	21	4	the	the	DT
cord-271972-qhr6iir6	21	5	cellular	cellular	JJ
cord-271972-qhr6iir6	21	6	RNA	RNA	NNP
cord-271972-qhr6iir6	21	7	destruction	destruction	NN
cord-271972-qhr6iir6	21	8	machinery	machinery	NN
cord-271972-qhr6iir6	21	9	likely	likely	RB
cord-271972-qhr6iir6	21	10	represents	represent	VBZ
cord-271972-qhr6iir6	21	11	a	a	DT
cord-271972-qhr6iir6	21	12	formidable	formidable	JJ
cord-271972-qhr6iir6	21	13	obstacle	obstacle	NN
cord-271972-qhr6iir6	21	14	to	to	IN
cord-271972-qhr6iir6	21	15	viral	viral	JJ
cord-271972-qhr6iir6	21	16	genomic	genomic	NN
cord-271972-qhr6iir6	21	17	and/or	and/or	CC
cord-271972-qhr6iir6	21	18	mRNA	mRNA	NNP
cord-271972-qhr6iir6	21	19	accumulation	accumulation	NN
cord-271972-qhr6iir6	21	20	and	and	CC
cord-271972-qhr6iir6	21	21	integrity	integrity	NN
cord-271972-qhr6iir6	21	22	.	.	.
cord-271972-qhr6iir6	22	1	Therefore	therefore	RB
cord-271972-qhr6iir6	22	2	,	,	,
cord-271972-qhr6iir6	22	3	while	while	IN
cord-271972-qhr6iir6	22	4	viral	viral	JJ
cord-271972-qhr6iir6	22	5	RNAs	rna	NNS
cord-271972-qhr6iir6	22	6	can	can	MD
cord-271972-qhr6iir6	22	7	be	be	VB
cord-271972-qhr6iir6	22	8	targeted	target	VBN
cord-271972-qhr6iir6	22	9	for	for	IN
cord-271972-qhr6iir6	22	10	turnover	turnover	NN
cord-271972-qhr6iir6	22	11	by	by	IN
cord-271972-qhr6iir6	22	12	the	the	DT
cord-271972-qhr6iir6	22	13	host	host	NN
cord-271972-qhr6iir6	22	14	machinery	machinery	NN
cord-271972-qhr6iir6	22	15	,	,	,
cord-271972-qhr6iir6	22	16	in	in	IN
cord-271972-qhr6iir6	22	17	many	many	JJ
cord-271972-qhr6iir6	22	18	cases	case	NNS
cord-271972-qhr6iir6	22	19	viruses	virus	NNS
cord-271972-qhr6iir6	22	20	have	have	VBP
cord-271972-qhr6iir6	22	21	evolved	evolve	VBN
cord-271972-qhr6iir6	22	22	to	to	TO
cord-271972-qhr6iir6	22	23	circumvent	circumvent	VB
cord-271972-qhr6iir6	22	24	and	and	CC
cord-271972-qhr6iir6	22	25	even	even	RB
cord-271972-qhr6iir6	22	26	subvert	subvert	VB
cord-271972-qhr6iir6	22	27	these	these	DT
cord-271972-qhr6iir6	22	28	pathways	pathway	NNS
cord-271972-qhr6iir6	22	29	to	to	TO
cord-271972-qhr6iir6	22	30	facilitate	facilitate	VB
cord-271972-qhr6iir6	22	31	their	-PRON-	PRP$
cord-271972-qhr6iir6	22	32	own	own	JJ
cord-271972-qhr6iir6	22	33	replication	replication	NN
cord-271972-qhr6iir6	22	34	.	.	.
cord-271972-qhr6iir6	23	1	This	this	DT
cord-271972-qhr6iir6	23	2	review	review	NN
cord-271972-qhr6iir6	23	3	will	will	MD
cord-271972-qhr6iir6	23	4	highlight	highlight	VB
cord-271972-qhr6iir6	23	5	both	both	PDT
cord-271972-qhr6iir6	23	6	these	these	DT
cord-271972-qhr6iir6	23	7	themes	theme	NNS
cord-271972-qhr6iir6	23	8	in	in	IN
cord-271972-qhr6iir6	23	9	relation	relation	NN
cord-271972-qhr6iir6	23	10	to	to	IN
cord-271972-qhr6iir6	23	11	the	the	DT
cord-271972-qhr6iir6	23	12	variety	variety	NN
cord-271972-qhr6iir6	23	13	of	of	IN
cord-271972-qhr6iir6	23	14	cellular	cellular	JJ
cord-271972-qhr6iir6	23	15	regulators	regulator	NNS
cord-271972-qhr6iir6	23	16	and	and	CC
cord-271972-qhr6iir6	23	17	effectors	effector	NNS
cord-271972-qhr6iir6	23	18	controlling	control	VBG
cord-271972-qhr6iir6	23	19	the	the	DT
cord-271972-qhr6iir6	23	20	ultimate	ultimate	JJ
cord-271972-qhr6iir6	23	21	fate	fate	NN
cord-271972-qhr6iir6	23	22	of	of	IN
cord-271972-qhr6iir6	23	23	RNA	RNA	NNP
cord-271972-qhr6iir6	23	24	in	in	IN
cord-271972-qhr6iir6	23	25	an	an	DT
cord-271972-qhr6iir6	23	26	infected	infected	JJ
cord-271972-qhr6iir6	23	27	cell	cell	NN
cord-271972-qhr6iir6	23	28	.	.	.
cord-271972-qhr6iir6	24	1	We	-PRON-	PRP
cord-271972-qhr6iir6	24	2	will	will	MD
cord-271972-qhr6iir6	24	3	focus	focus	VB
cord-271972-qhr6iir6	24	4	on	on	IN
cord-271972-qhr6iir6	24	5	how	how	WRB
cord-271972-qhr6iir6	24	6	viruses	virus	NNS
cord-271972-qhr6iir6	24	7	are	be	VBP
cord-271972-qhr6iir6	24	8	influenced	influence	VBN
cord-271972-qhr6iir6	24	9	by	by	IN
cord-271972-qhr6iir6	24	10	the	the	DT
cord-271972-qhr6iir6	24	11	basal	basal	NN
cord-271972-qhr6iir6	24	12	mRNA	mRNA	NNP
cord-271972-qhr6iir6	24	13	decay	decay	NN
cord-271972-qhr6iir6	24	14	machinery	machinery	NN
cord-271972-qhr6iir6	24	15	,	,	,
cord-271972-qhr6iir6	24	16	DEADENYLATION	DEADENYLATION	NNP
cord-271972-qhr6iir6	24	17	Cellular	Cellular	NNP
cord-271972-qhr6iir6	24	18	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	24	19	are	be	VBP
cord-271972-qhr6iir6	24	20	protected	protect	VBN
cord-271972-qhr6iir6	24	21	at	at	IN
cord-271972-qhr6iir6	24	22	their	-PRON-	PRP$
cord-271972-qhr6iir6	24	23	termini	terminus	NNS
cord-271972-qhr6iir6	24	24	by	by	IN
cord-271972-qhr6iir6	24	25	a	a	DT
cord-271972-qhr6iir6	24	26	5	5	CD
cord-271972-qhr6iir6	24	27	7-methylguanosine	7-methylguanosine	CD
cord-271972-qhr6iir6	24	28	cap	cap	NN
cord-271972-qhr6iir6	24	29	and	and	CC
cord-271972-qhr6iir6	24	30	a	a	DT
cord-271972-qhr6iir6	24	31	3	3	CD
cord-271972-qhr6iir6	24	32	nontemplated	nontemplate	VBN
cord-271972-qhr6iir6	24	33	poly(A	poly(A	NNP
cord-271972-qhr6iir6	24	34	)	)	-RRB-
cord-271972-qhr6iir6	24	35	tail	tail	NN
cord-271972-qhr6iir6	24	36	,	,	,
cord-271972-qhr6iir6	24	37	which	which	WDT
cord-271972-qhr6iir6	24	38	facilitate	facilitate	VBP
cord-271972-qhr6iir6	24	39	translation	translation	NN
cord-271972-qhr6iir6	24	40	and	and	CC
cord-271972-qhr6iir6	24	41	restrict	restrict	VB
cord-271972-qhr6iir6	24	42	access	access	NN
cord-271972-qhr6iir6	24	43	of	of	IN
cord-271972-qhr6iir6	24	44	exonucleases	exonuclease	NNS
cord-271972-qhr6iir6	24	45	.	.	.
cord-271972-qhr6iir6	25	1	Within	within	IN
cord-271972-qhr6iir6	25	2	the	the	DT
cord-271972-qhr6iir6	25	3	nucleus	nucleus	NN
cord-271972-qhr6iir6	25	4	,	,	,
cord-271972-qhr6iir6	25	5	deadenylases	deadenylases	NNP
cord-271972-qhr6iir6	25	6	trim	trim	VBP
cord-271972-qhr6iir6	25	7	poly(A	poly(a	NN
cord-271972-qhr6iir6	25	8	)	)	-RRB-
cord-271972-qhr6iir6	26	1	tails	tail	NNS
cord-271972-qhr6iir6	26	2	for	for	IN
cord-271972-qhr6iir6	26	3	mRNA	mRNA	NNP
cord-271972-qhr6iir6	26	4	export	export	NN
cord-271972-qhr6iir6	26	5	and	and	CC
cord-271972-qhr6iir6	26	6	participate	participate	VB
cord-271972-qhr6iir6	26	7	in	in	IN
cord-271972-qhr6iir6	26	8	the	the	DT
cord-271972-qhr6iir6	26	9	destruction	destruction	NN
cord-271972-qhr6iir6	26	10	of	of	IN
cord-271972-qhr6iir6	26	11	non	non	JJ
cord-271972-qhr6iir6	26	12	-	-	JJ
cord-271972-qhr6iir6	26	13	coding	coding	JJ
cord-271972-qhr6iir6	26	14	or	or	CC
cord-271972-qhr6iir6	26	15	aberrant	aberrant	JJ
cord-271972-qhr6iir6	26	16	transcripts	transcript	NNS
cord-271972-qhr6iir6	26	17	.	.	.
cord-271972-qhr6iir6	27	1	1	1	LS
cord-271972-qhr6iir6	28	1	In	in	IN
cord-271972-qhr6iir6	28	2	the	the	DT
cord-271972-qhr6iir6	28	3	cytoplasm	cytoplasm	NN
cord-271972-qhr6iir6	28	4	,	,	,
cord-271972-qhr6iir6	28	5	poly(A	poly(a	JJ
cord-271972-qhr6iir6	28	6	)	)	-RRB-
cord-271972-qhr6iir6	29	1	tail	tail	NN
cord-271972-qhr6iir6	29	2	removal	removal	NN
cord-271972-qhr6iir6	29	3	is	be	VBZ
cord-271972-qhr6iir6	29	4	the	the	DT
cord-271972-qhr6iir6	29	5	first	first	JJ
cord-271972-qhr6iir6	29	6	and	and	CC
cord-271972-qhr6iir6	29	7	often	often	RB
cord-271972-qhr6iir6	29	8	the	the	DT
cord-271972-qhr6iir6	29	9	rate	rate	NN
cord-271972-qhr6iir6	29	10	-	-	HYPH
cord-271972-qhr6iir6	29	11	limiting	limit	VBG
cord-271972-qhr6iir6	29	12	step	step	NN
cord-271972-qhr6iir6	29	13	of	of	IN
cord-271972-qhr6iir6	29	14	general	general	NNP
cord-271972-qhr6iir6	29	15	mRNA	mRNA	NNP
cord-271972-qhr6iir6	29	16	turnover	turnover	NN
cord-271972-qhr6iir6	29	17	and	and	CC
cord-271972-qhr6iir6	29	18	is	be	VBZ
cord-271972-qhr6iir6	29	19	usually	usually	RB
cord-271972-qhr6iir6	29	20	required	require	VBN
cord-271972-qhr6iir6	29	21	both	both	CC
cord-271972-qhr6iir6	29	22	for	for	IN
cord-271972-qhr6iir6	29	23	subsequent	subsequent	JJ
cord-271972-qhr6iir6	29	24	decapping	decapping	NN
cord-271972-qhr6iir6	29	25	and	and	CC
cord-271972-qhr6iir6	29	26	degradation	degradation	NN
cord-271972-qhr6iir6	29	27	of	of	IN
cord-271972-qhr6iir6	29	28	the	the	DT
cord-271972-qhr6iir6	29	29	message	message	NN
cord-271972-qhr6iir6	29	30	body	body	NN
cord-271972-qhr6iir6	29	31	2	2	CD
cord-271972-qhr6iir6	29	32	(	(	-LRB-
cord-271972-qhr6iir6	29	33	Figure	figure	NN
cord-271972-qhr6iir6	29	34	1	1	CD
cord-271972-qhr6iir6	29	35	)	)	-RRB-
cord-271972-qhr6iir6	29	36	.	.	.
cord-271972-qhr6iir6	30	1	Several	several	JJ
cord-271972-qhr6iir6	30	2	deadenylase	deadenylase	NNP
cord-271972-qhr6iir6	30	3	complexes	complex	NNS
cord-271972-qhr6iir6	30	4	have	have	VBP
cord-271972-qhr6iir6	30	5	been	be	VBN
cord-271972-qhr6iir6	30	6	identified	identify	VBN
cord-271972-qhr6iir6	30	7	,	,	,
cord-271972-qhr6iir6	30	8	including	include	VBG
cord-271972-qhr6iir6	30	9	Ccr4-Caf1-Not1	Ccr4-Caf1-Not1	NNP
cord-271972-qhr6iir6	30	10	,	,	,
cord-271972-qhr6iir6	30	11	PAN2-PAN3	PAN2-PAN3	NNP
cord-271972-qhr6iir6	30	12	,	,	,
cord-271972-qhr6iir6	30	13	and	and	CC
cord-271972-qhr6iir6	30	14	PARN	PARN	NNP
cord-271972-qhr6iir6	30	15	.	.	.
cord-271972-qhr6iir6	31	1	3	3	LS
cord-271972-qhr6iir6	32	1	While	while	IN
cord-271972-qhr6iir6	32	2	to	to	IN
cord-271972-qhr6iir6	32	3	date	date	NN
cord-271972-qhr6iir6	32	4	no	no	DT
cord-271972-qhr6iir6	32	5	viruses	virus	NNS
cord-271972-qhr6iir6	32	6	have	have	VBP
cord-271972-qhr6iir6	32	7	been	be	VBN
cord-271972-qhr6iir6	32	8	shown	show	VBN
cord-271972-qhr6iir6	32	9	to	to	TO
cord-271972-qhr6iir6	32	10	directly	directly	RB
cord-271972-qhr6iir6	32	11	interfere	interfere	VB
cord-271972-qhr6iir6	32	12	with	with	IN
cord-271972-qhr6iir6	32	13	specific	specific	JJ
cord-271972-qhr6iir6	32	14	deadenylases	deadenylase	NNS
cord-271972-qhr6iir6	32	15	,	,	,
cord-271972-qhr6iir6	32	16	several	several	JJ
cord-271972-qhr6iir6	32	17	examples	example	NNS
cord-271972-qhr6iir6	32	18	exist	exist	VBP
cord-271972-qhr6iir6	32	19	of	of	IN
cord-271972-qhr6iir6	32	20	viral	viral	JJ
cord-271972-qhr6iir6	32	21	RNAs	rna	NNS
cord-271972-qhr6iir6	32	22	evading	evade	VBG
cord-271972-qhr6iir6	32	23	the	the	DT
cord-271972-qhr6iir6	32	24	general	general	JJ
cord-271972-qhr6iir6	32	25	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	32	26	process	process	NN
cord-271972-qhr6iir6	32	27	.	.	.
cord-271972-qhr6iir6	33	1	Alphaviruses	Alphaviruses	NNP
cord-271972-qhr6iir6	33	2	such	such	JJ
cord-271972-qhr6iir6	33	3	as	as	IN
cord-271972-qhr6iir6	33	4	Sindbis	Sindbis	NNP
cord-271972-qhr6iir6	33	5	virus	virus	NN
cord-271972-qhr6iir6	33	6	(	(	-LRB-
cord-271972-qhr6iir6	33	7	SINV	SINV	NNP
cord-271972-qhr6iir6	33	8	)	)	-RRB-
cord-271972-qhr6iir6	33	9	and	and	CC
cord-271972-qhr6iir6	33	10	Venezuelan	venezuelan	JJ
cord-271972-qhr6iir6	33	11	equine	equine	NN
cord-271972-qhr6iir6	33	12	encephalitis	encephalitis	NN
cord-271972-qhr6iir6	33	13	virus	virus	NN
cord-271972-qhr6iir6	33	14	(	(	-LRB-
cord-271972-qhr6iir6	33	15	VEEV	VEEV	NNP
cord-271972-qhr6iir6	33	16	)	)	-RRB-
cord-271972-qhr6iir6	33	17	are	be	VBP
cord-271972-qhr6iir6	33	18	positive	positive	JJ
cord-271972-qhr6iir6	33	19	-	-	HYPH
cord-271972-qhr6iir6	33	20	sense	sense	NN
cord-271972-qhr6iir6	33	21	single	single	JJ
cord-271972-qhr6iir6	33	22	-	-	HYPH
cord-271972-qhr6iir6	33	23	stranded	strand	VBN
cord-271972-qhr6iir6	33	24	RNA	RNA	NNP
cord-271972-qhr6iir6	33	25	[	[	-LRB-
cord-271972-qhr6iir6	33	26	(	(	-LRB-
cord-271972-qhr6iir6	33	27	+	+	JJ
cord-271972-qhr6iir6	33	28	)	)	-RRB-
cord-271972-qhr6iir6	33	29	RNA	RNA	NNP
cord-271972-qhr6iir6	33	30	]	]	-RRB-
cord-271972-qhr6iir6	33	31	viruses	virus	NNS
cord-271972-qhr6iir6	33	32	whose	whose	WP$
cord-271972-qhr6iir6	33	33	genomic	genomic	JJ
cord-271972-qhr6iir6	33	34	RNAs	rna	NNS
cord-271972-qhr6iir6	33	35	are	be	VBP
cord-271972-qhr6iir6	33	36	both	both	DT
cord-271972-qhr6iir6	33	37	capped	cap	VBN
cord-271972-qhr6iir6	33	38	FIGURE	figure	NN
cord-271972-qhr6iir6	33	39	1	1	CD
cord-271972-qhr6iir6	33	40	|	|	NNP
cord-271972-qhr6iir6	33	41	Basal	Basal	NNP
cord-271972-qhr6iir6	33	42	pathways	pathway	NNS
cord-271972-qhr6iir6	33	43	of	of	IN
cord-271972-qhr6iir6	33	44	cellular	cellular	JJ
cord-271972-qhr6iir6	33	45	mRNA	mrna	NN
cord-271972-qhr6iir6	33	46	decay	decay	NN
cord-271972-qhr6iir6	33	47	.	.	.
cord-271972-qhr6iir6	34	1	Degradation	degradation	NN
cord-271972-qhr6iir6	34	2	of	of	IN
cord-271972-qhr6iir6	34	3	normal	normal	JJ
cord-271972-qhr6iir6	34	4	cellular	cellular	JJ
cord-271972-qhr6iir6	34	5	mRNA	mrna	NN
cord-271972-qhr6iir6	34	6	initiates	initiate	VBZ
cord-271972-qhr6iir6	34	7	with	with	IN
cord-271972-qhr6iir6	34	8	removal	removal	NN
cord-271972-qhr6iir6	34	9	of	of	IN
cord-271972-qhr6iir6	34	10	the	the	DT
cord-271972-qhr6iir6	34	11	poly(A	poly(a	JJ
cord-271972-qhr6iir6	34	12	)	)	-RRB-
cord-271972-qhr6iir6	34	13	tail	tail	NN
cord-271972-qhr6iir6	34	14	by	by	IN
cord-271972-qhr6iir6	34	15	one	one	CD
cord-271972-qhr6iir6	34	16	of	of	IN
cord-271972-qhr6iir6	34	17	the	the	DT
cord-271972-qhr6iir6	34	18	cellular	cellular	JJ
cord-271972-qhr6iir6	34	19	deadenylases	deadenylase	NNS
cord-271972-qhr6iir6	34	20	.	.	.
cord-271972-qhr6iir6	35	1	Subsequently	subsequently	RB
cord-271972-qhr6iir6	35	2	,	,	,
cord-271972-qhr6iir6	35	3	the	the	DT
cord-271972-qhr6iir6	35	4	Lsm1	Lsm1	NNP
cord-271972-qhr6iir6	35	5	-	-	HYPH
cord-271972-qhr6iir6	35	6	7	7	CD
cord-271972-qhr6iir6	35	7	protein	protein	NN
cord-271972-qhr6iir6	35	8	complex	complex	NN
cord-271972-qhr6iir6	35	9	binds	bind	VBZ
cord-271972-qhr6iir6	35	10	the	the	DT
cord-271972-qhr6iir6	35	11	3	3	CD
cord-271972-qhr6iir6	35	12	untranslated	untranslated	JJ
cord-271972-qhr6iir6	35	13	region	region	NN
cord-271972-qhr6iir6	35	14	(	(	-LRB-
cord-271972-qhr6iir6	35	15	UTR	UTR	NNP
cord-271972-qhr6iir6	35	16	)	)	-RRB-
cord-271972-qhr6iir6	35	17	of	of	IN
cord-271972-qhr6iir6	35	18	the	the	DT
cord-271972-qhr6iir6	35	19	deadenylated	deadenylate	VBN
cord-271972-qhr6iir6	35	20	messages	message	NNS
cord-271972-qhr6iir6	35	21	and	and	CC
cord-271972-qhr6iir6	35	22	stimulates	stimulate	VBZ
cord-271972-qhr6iir6	35	23	decapping	decapping	NN
cord-271972-qhr6iir6	35	24	by	by	IN
cord-271972-qhr6iir6	35	25	the	the	DT
cord-271972-qhr6iir6	35	26	Dcp2	Dcp2	NNP
cord-271972-qhr6iir6	35	27	enzyme	enzyme	NN
cord-271972-qhr6iir6	35	28	and	and	CC
cord-271972-qhr6iir6	35	29	its	-PRON-	PRP$
cord-271972-qhr6iir6	35	30	activator	activator	NN
cord-271972-qhr6iir6	35	31	protein	protein	NN
cord-271972-qhr6iir6	35	32	Dcp1	Dcp1	NNP
cord-271972-qhr6iir6	35	33	.	.	.
cord-271972-qhr6iir6	36	1	The	the	DT
cord-271972-qhr6iir6	36	2	message	message	NN
cord-271972-qhr6iir6	36	3	body	body	NN
cord-271972-qhr6iir6	36	4	is	be	VBZ
cord-271972-qhr6iir6	36	5	subject	subject	JJ
cord-271972-qhr6iir6	36	6	to	to	IN
cord-271972-qhr6iir6	36	7	3	3	CD
cord-271972-qhr6iir6	36	8	→5	→5	JJ
cord-271972-qhr6iir6	36	9	exonucleolytic	exonucleolytic	VBN
cord-271972-qhr6iir6	36	10	decay	decay	NN
cord-271972-qhr6iir6	36	11	by	by	IN
cord-271972-qhr6iir6	36	12	the	the	DT
cord-271972-qhr6iir6	36	13	exosome	exosome	NN
cord-271972-qhr6iir6	36	14	or	or	CC
cord-271972-qhr6iir6	37	1	5	5	CD
cord-271972-qhr6iir6	37	2	→3	→3	NNS
cord-271972-qhr6iir6	37	3	decay	decay	VBP
cord-271972-qhr6iir6	37	4	by	by	IN
cord-271972-qhr6iir6	37	5	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	37	6	.	.	.
cord-271972-qhr6iir6	38	1	and	and	CC
cord-271972-qhr6iir6	38	2	polyadenylated	polyadenylate	VBD
cord-271972-qhr6iir6	38	3	,	,	,
cord-271972-qhr6iir6	38	4	resembling	resemble	VBG
cord-271972-qhr6iir6	38	5	cellular	cellular	JJ
cord-271972-qhr6iir6	38	6	mRNAs	mrna	NNS
cord-271972-qhr6iir6	38	7	.	.	.
cord-271972-qhr6iir6	39	1	Consequently	consequently	RB
cord-271972-qhr6iir6	39	2	,	,	,
cord-271972-qhr6iir6	39	3	to	to	TO
cord-271972-qhr6iir6	39	4	avoid	avoid	VB
cord-271972-qhr6iir6	39	5	degradation	degradation	NN
cord-271972-qhr6iir6	39	6	,	,	,
cord-271972-qhr6iir6	39	7	SINV	SINV	NNP
cord-271972-qhr6iir6	39	8	and	and	CC
cord-271972-qhr6iir6	39	9	VEEV	VEEV	NNP
cord-271972-qhr6iir6	39	10	RNAs	rna	NNS
cord-271972-qhr6iir6	39	11	have	have	VBP
cord-271972-qhr6iir6	39	12	evolved	evolve	VBN
cord-271972-qhr6iir6	39	13	sequences	sequence	NNS
cord-271972-qhr6iir6	39	14	that	that	WDT
cord-271972-qhr6iir6	39	15	can	can	MD
cord-271972-qhr6iir6	39	16	stall	stall	VB
cord-271972-qhr6iir6	39	17	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	39	18	4	4	CD
cord-271972-qhr6iir6	39	19	(	(	-LRB-
cord-271972-qhr6iir6	39	20	Figure	figure	NN
cord-271972-qhr6iir6	39	21	2	2	CD
cord-271972-qhr6iir6	39	22	(	(	-LRB-
cord-271972-qhr6iir6	39	23	a	a	NN
cord-271972-qhr6iir6	39	24	)	)	-RRB-
cord-271972-qhr6iir6	39	25	)	)	-RRB-
cord-271972-qhr6iir6	39	26	.	.	.
cord-271972-qhr6iir6	40	1	A	a	DT
cord-271972-qhr6iir6	40	2	combination	combination	NN
cord-271972-qhr6iir6	40	3	of	of	IN
cord-271972-qhr6iir6	40	4	conserved	conserved	JJ
cord-271972-qhr6iir6	40	5	sequences	sequence	NNS
cord-271972-qhr6iir6	40	6	in	in	IN
cord-271972-qhr6iir6	40	7	the	the	DT
cord-271972-qhr6iir6	40	8	3	3	CD
cord-271972-qhr6iir6	40	9	untranslated	untranslated	JJ
cord-271972-qhr6iir6	40	10	region	region	NN
cord-271972-qhr6iir6	40	11	(	(	-LRB-
cord-271972-qhr6iir6	40	12	UTR	UTR	NNP
cord-271972-qhr6iir6	40	13	)	)	-RRB-
cord-271972-qhr6iir6	40	14	of	of	IN
cord-271972-qhr6iir6	40	15	the	the	DT
cord-271972-qhr6iir6	40	16	viral	viral	JJ
cord-271972-qhr6iir6	40	17	genomes	genome	NNS
cord-271972-qhr6iir6	40	18	act	act	VBP
cord-271972-qhr6iir6	40	19	in	in	IN
cord-271972-qhr6iir6	40	20	cis	cis	NNP
cord-271972-qhr6iir6	40	21	to	to	TO
cord-271972-qhr6iir6	40	22	repress	repress	VB
cord-271972-qhr6iir6	40	23	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	40	24	in	in	IN
cord-271972-qhr6iir6	40	25	mosquito	mosquito	NN
cord-271972-qhr6iir6	40	26	cell	cell	NN
cord-271972-qhr6iir6	40	27	extracts	extract	NNS
cord-271972-qhr6iir6	40	28	,	,	,
cord-271972-qhr6iir6	40	29	presumably	presumably	RB
cord-271972-qhr6iir6	40	30	by	by	IN
cord-271972-qhr6iir6	40	31	mediating	mediate	VBG
cord-271972-qhr6iir6	40	32	interaction	interaction	NN
cord-271972-qhr6iir6	40	33	with	with	IN
cord-271972-qhr6iir6	40	34	a	a	DT
cord-271972-qhr6iir6	40	35	protective	protective	JJ
cord-271972-qhr6iir6	40	36	cellular	cellular	JJ
cord-271972-qhr6iir6	40	37	factor	factor	NN
cord-271972-qhr6iir6	40	38	.	.	.
cord-271972-qhr6iir6	41	1	4	4	LS
cord-271972-qhr6iir6	42	1	A	a	DT
cord-271972-qhr6iir6	42	2	38-kDa	38-kda	CD
cord-271972-qhr6iir6	42	3	mosquito	mosquito	NN
cord-271972-qhr6iir6	42	4	protein	protein	NN
cord-271972-qhr6iir6	42	5	binds	bind	VBZ
cord-271972-qhr6iir6	42	6	both	both	CC
cord-271972-qhr6iir6	42	7	the	the	DT
cord-271972-qhr6iir6	42	8	SINV	SINV	NNP
cord-271972-qhr6iir6	42	9	and	and	CC
cord-271972-qhr6iir6	42	10	the	the	DT
cord-271972-qhr6iir6	42	11	VEEV	VEEV	NNP
cord-271972-qhr6iir6	42	12	3	3	CD
cord-271972-qhr6iir6	42	13	UTRs	utr	NNS
cord-271972-qhr6iir6	42	14	and	and	CC
cord-271972-qhr6iir6	42	15	can	can	MD
cord-271972-qhr6iir6	42	16	be	be	VB
cord-271972-qhr6iir6	42	17	specifically	specifically	RB
cord-271972-qhr6iir6	42	18	titrated	titrate	VBN
cord-271972-qhr6iir6	42	19	away	away	RB
cord-271972-qhr6iir6	42	20	in	in	IN
cord-271972-qhr6iir6	42	21	the	the	DT
cord-271972-qhr6iir6	42	22	presence	presence	NN
cord-271972-qhr6iir6	42	23	of	of	IN
cord-271972-qhr6iir6	42	24	excess	excess	JJ
cord-271972-qhr6iir6	42	25	viral	viral	JJ
cord-271972-qhr6iir6	42	26	UTR	UTR	NNP
cord-271972-qhr6iir6	42	27	sequences	sequence	NNS
cord-271972-qhr6iir6	42	28	,	,	,
cord-271972-qhr6iir6	42	29	leading	lead	VBG
cord-271972-qhr6iir6	42	30	to	to	IN
cord-271972-qhr6iir6	42	31	decreased	decrease	VBN
cord-271972-qhr6iir6	42	32	viral	viral	JJ
cord-271972-qhr6iir6	42	33	RNA	rna	NN
cord-271972-qhr6iir6	42	34	stability	stability	NN
cord-271972-qhr6iir6	42	35	.	.	.
cord-271972-qhr6iir6	43	1	Interestingly	interestingly	RB
cord-271972-qhr6iir6	43	2	,	,	,
cord-271972-qhr6iir6	43	3	removal	removal	NN
cord-271972-qhr6iir6	43	4	of	of	IN
cord-271972-qhr6iir6	43	5	the	the	DT
cord-271972-qhr6iir6	43	6	38-kDa	38-kda	CD
cord-271972-qhr6iir6	43	7	protein	protein	NN
cord-271972-qhr6iir6	43	8	from	from	IN
cord-271972-qhr6iir6	43	9	SINV	SINV	NNP
cord-271972-qhr6iir6	43	10	RNA	RNA	NNP
cord-271972-qhr6iir6	43	11	leads	lead	VBZ
cord-271972-qhr6iir6	43	12	to	to	IN
cord-271972-qhr6iir6	43	13	increased	increase	VBN
cord-271972-qhr6iir6	43	14	binding	binding	NN
cord-271972-qhr6iir6	43	15	of	of	IN
cord-271972-qhr6iir6	43	16	a	a	DT
cord-271972-qhr6iir6	43	17	32-kDa	32-kda	CD
cord-271972-qhr6iir6	43	18	mosquito	mosquito	NN
cord-271972-qhr6iir6	43	19	protein	protein	NN
cord-271972-qhr6iir6	43	20	.	.	.
cord-271972-qhr6iir6	44	1	This	this	DT
cord-271972-qhr6iir6	44	2	suggests	suggest	VBZ
cord-271972-qhr6iir6	44	3	a	a	DT
cord-271972-qhr6iir6	44	4	mechanism	mechanism	NN
cord-271972-qhr6iir6	44	5	whereby	whereby	WRB
cord-271972-qhr6iir6	44	6	the	the	DT
cord-271972-qhr6iir6	44	7	viral	viral	JJ
cord-271972-qhr6iir6	44	8	UTRs	utr	NNS
cord-271972-qhr6iir6	44	9	may	may	MD
cord-271972-qhr6iir6	44	10	be	be	VB
cord-271972-qhr6iir6	44	11	stabilized	stabilize	VBN
cord-271972-qhr6iir6	44	12	by	by	IN
cord-271972-qhr6iir6	44	13	displacing	displace	VBG
cord-271972-qhr6iir6	44	14	a	a	DT
cord-271972-qhr6iir6	44	15	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	44	16	-	-	HYPH
cord-271972-qhr6iir6	44	17	promoting	promote	VBG
cord-271972-qhr6iir6	44	18	factor	factor	NN
cord-271972-qhr6iir6	44	19	via	via	IN
cord-271972-qhr6iir6	44	20	preferential	preferential	JJ
cord-271972-qhr6iir6	44	21	binding	binding	NN
cord-271972-qhr6iir6	44	22	to	to	IN
cord-271972-qhr6iir6	44	23	a	a	DT
cord-271972-qhr6iir6	44	24	protective	protective	JJ
cord-271972-qhr6iir6	44	25	factor	factor	NN
cord-271972-qhr6iir6	44	26	.	.	.
cord-271972-qhr6iir6	45	1	The	the	DT
cord-271972-qhr6iir6	45	2	identity	identity	NN
cord-271972-qhr6iir6	45	3	of	of	IN
cord-271972-qhr6iir6	45	4	these	these	DT
cord-271972-qhr6iir6	45	5	two	two	CD
cord-271972-qhr6iir6	45	6	cellular	cellular	JJ
cord-271972-qhr6iir6	45	7	proteins	protein	NNS
cord-271972-qhr6iir6	45	8	and	and	CC
cord-271972-qhr6iir6	45	9	their	-PRON-	PRP$
cord-271972-qhr6iir6	45	10	conservation	conservation	NN
cord-271972-qhr6iir6	45	11	across	across	IN
cord-271972-qhr6iir6	45	12	species	specie	NNS
cord-271972-qhr6iir6	45	13	is	be	VBZ
cord-271972-qhr6iir6	45	14	currently	currently	RB
cord-271972-qhr6iir6	45	15	unknown	unknown	JJ
cord-271972-qhr6iir6	45	16	.	.	.
cord-271972-qhr6iir6	46	1	However	however	RB
cord-271972-qhr6iir6	46	2	,	,	,
cord-271972-qhr6iir6	46	3	in	in	IN
cord-271972-qhr6iir6	46	4	the	the	DT
cord-271972-qhr6iir6	46	5	future	future	NN
cord-271972-qhr6iir6	46	6	their	-PRON-	PRP$
cord-271972-qhr6iir6	46	7	characterization	characterization	NN
cord-271972-qhr6iir6	46	8	will	will	MD
cord-271972-qhr6iir6	46	9	likely	likely	RB
cord-271972-qhr6iir6	46	10	provide	provide	VB
cord-271972-qhr6iir6	46	11	insight	insight	NN
cord-271972-qhr6iir6	46	12	both	both	DT
cord-271972-qhr6iir6	46	13	into	into	IN
cord-271972-qhr6iir6	46	14	how	how	WRB
cord-271972-qhr6iir6	46	15	both	both	DT
cord-271972-qhr6iir6	46	16	cellular	cellular	JJ
cord-271972-qhr6iir6	46	17	mRNA	mrna	NN
cord-271972-qhr6iir6	46	18	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	46	19	and	and	CC
cord-271972-qhr6iir6	46	20	viral	viral	JJ
cord-271972-qhr6iir6	46	21	RNA	RNA	NNP
cord-271972-qhr6iir6	46	22	stabilization	stabilization	NN
cord-271972-qhr6iir6	46	23	are	be	VBP
cord-271972-qhr6iir6	46	24	orchestrated	orchestrate	VBN
cord-271972-qhr6iir6	46	25	.	.	.
cord-271972-qhr6iir6	47	1	A	a	DT
cord-271972-qhr6iir6	47	2	second	second	JJ
cord-271972-qhr6iir6	47	3	mechanism	mechanism	NN
cord-271972-qhr6iir6	47	4	of	of	IN
cord-271972-qhr6iir6	47	5	protection	protection	NN
cord-271972-qhr6iir6	47	6	from	from	IN
cord-271972-qhr6iir6	47	7	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	47	8	is	be	VBZ
cord-271972-qhr6iir6	47	9	used	use	VBN
cord-271972-qhr6iir6	47	10	by	by	IN
cord-271972-qhr6iir6	47	11	a	a	DT
cord-271972-qhr6iir6	47	12	highly	highly	RB
cord-271972-qhr6iir6	47	13	abundant	abundant	JJ
cord-271972-qhr6iir6	47	14	non	non	JJ
cord-271972-qhr6iir6	47	15	-	-	JJ
cord-271972-qhr6iir6	47	16	coding	coding	JJ
cord-271972-qhr6iir6	47	17	nuclear	nuclear	JJ
cord-271972-qhr6iir6	47	18	RNA	RNA	NNP
cord-271972-qhr6iir6	47	19	of	of	IN
cord-271972-qhr6iir6	47	20	Kaposi	Kaposi	NNP
cord-271972-qhr6iir6	47	21	's	's	POS
cord-271972-qhr6iir6	47	22	sarcoma	sarcoma	NN
cord-271972-qhr6iir6	47	23	-	-	HYPH
cord-271972-qhr6iir6	47	24	associated	associate	VBN
cord-271972-qhr6iir6	47	25	herpesvirus	herpesvirus	NN
cord-271972-qhr6iir6	47	26	(	(	-LRB-
cord-271972-qhr6iir6	47	27	KSHV	KSHV	NNP
cord-271972-qhr6iir6	47	28	)	)	-RRB-
cord-271972-qhr6iir6	47	29	,	,	,
cord-271972-qhr6iir6	47	30	termed	term	VBN
cord-271972-qhr6iir6	47	31	PAN	PAN	NNP
cord-271972-qhr6iir6	47	32	(	(	-LRB-
cord-271972-qhr6iir6	47	33	Figure	figure	NN
cord-271972-qhr6iir6	47	34	2(a	2(a	CD
cord-271972-qhr6iir6	47	35	)	)	-RRB-
cord-271972-qhr6iir6	47	36	)	)	-RRB-
cord-271972-qhr6iir6	47	37	.	.	.
cord-271972-qhr6iir6	48	1	PAN	PAN	NNP
cord-271972-qhr6iir6	48	2	contains	contain	VBZ
cord-271972-qhr6iir6	48	3	a	a	DT
cord-271972-qhr6iir6	48	4	79-nt	79-nt	CD
cord-271972-qhr6iir6	48	5	element	element	NN
cord-271972-qhr6iir6	48	6	(	(	-LRB-
cord-271972-qhr6iir6	48	7	ENE	ENE	NNP
cord-271972-qhr6iir6	48	8	)	)	-RRB-
cord-271972-qhr6iir6	48	9	near	near	IN
cord-271972-qhr6iir6	48	10	its	-PRON-	PRP$
cord-271972-qhr6iir6	48	11	3	3	CD
cord-271972-qhr6iir6	48	12	end	end	NN
cord-271972-qhr6iir6	48	13	that	that	WDT
cord-271972-qhr6iir6	48	14	acts	act	VBZ
cord-271972-qhr6iir6	48	15	post	post	NN
cord-271972-qhr6iir6	48	16	-	-	NN
cord-271972-qhr6iir6	48	17	transcriptionally	transcriptionally	RB
cord-271972-qhr6iir6	48	18	to	to	TO
cord-271972-qhr6iir6	48	19	stabilize	stabilize	VB
cord-271972-qhr6iir6	48	20	the	the	DT
cord-271972-qhr6iir6	48	21	RNA	RNA	NNP
cord-271972-qhr6iir6	48	22	and	and	CC
cord-271972-qhr6iir6	48	23	promote	promote	VB
cord-271972-qhr6iir6	48	24	its	-PRON-	PRP$
cord-271972-qhr6iir6	48	25	nuclear	nuclear	JJ
cord-271972-qhr6iir6	48	26	retention	retention	NN
cord-271972-qhr6iir6	48	27	.	.	.
cord-271972-qhr6iir6	49	1	5	5	LS
cord-271972-qhr6iir6	50	1	The	the	DT
cord-271972-qhr6iir6	50	2	ENE	ENE	NNP
cord-271972-qhr6iir6	50	3	forms	form	VBZ
cord-271972-qhr6iir6	50	4	a	a	DT
cord-271972-qhr6iir6	50	5	stem	stem	NN
cord-271972-qhr6iir6	50	6	-	-	HYPH
cord-271972-qhr6iir6	50	7	loop	loop	NN
cord-271972-qhr6iir6	50	8	structure	structure	NN
cord-271972-qhr6iir6	50	9	containing	contain	VBG
cord-271972-qhr6iir6	50	10	a	a	DT
cord-271972-qhr6iir6	50	11	U	u	NN
cord-271972-qhr6iir6	50	12	-	-	HYPH
cord-271972-qhr6iir6	50	13	rich	rich	JJ
cord-271972-qhr6iir6	50	14	loop	loop	NN
cord-271972-qhr6iir6	50	15	.	.	.
cord-271972-qhr6iir6	51	1	This	this	DT
cord-271972-qhr6iir6	51	2	loop	loop	NN
cord-271972-qhr6iir6	51	3	makes	make	VBZ
cord-271972-qhr6iir6	51	4	intramolecular	intramolecular	JJ
cord-271972-qhr6iir6	51	5	contacts	contact	NNS
cord-271972-qhr6iir6	51	6	with	with	IN
cord-271972-qhr6iir6	51	7	the	the	DT
cord-271972-qhr6iir6	51	8	PAN	PAN	NNP
cord-271972-qhr6iir6	51	9	poly(A	poly(A	NNP
cord-271972-qhr6iir6	51	10	)	)	-RRB-
cord-271972-qhr6iir6	51	11	tail	tail	NN
cord-271972-qhr6iir6	51	12	and	and	CC
cord-271972-qhr6iir6	51	13	blocks	block	VBZ
cord-271972-qhr6iir6	51	14	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	51	15	,	,	,
cord-271972-qhr6iir6	51	16	presumably	presumably	RB
cord-271972-qhr6iir6	51	17	in	in	IN
cord-271972-qhr6iir6	51	18	part	part	NN
cord-271972-qhr6iir6	51	19	by	by	IN
cord-271972-qhr6iir6	51	20	preventing	prevent	VBG
cord-271972-qhr6iir6	51	21	access	access	NN
cord-271972-qhr6iir6	51	22	of	of	IN
cord-271972-qhr6iir6	51	23	deadenylases	deadenylase	NNS
cord-271972-qhr6iir6	51	24	to	to	IN
cord-271972-qhr6iir6	51	25	the	the	DT
cord-271972-qhr6iir6	51	26	RNA	RNA	NNP
cord-271972-qhr6iir6	51	27	.	.	.
cord-271972-qhr6iir6	52	1	6	6	CD
cord-271972-qhr6iir6	53	1	However	however	RB
cord-271972-qhr6iir6	53	2	,	,	,
cord-271972-qhr6iir6	53	3	a	a	DT
cord-271972-qhr6iir6	53	4	simple	simple	JJ
cord-271972-qhr6iir6	53	5	U	u	NN
cord-271972-qhr6iir6	53	6	-	-	HYPH
cord-271972-qhr6iir6	53	7	rich	rich	JJ
cord-271972-qhr6iir6	53	8	stretch	stretch	NN
cord-271972-qhr6iir6	53	9	is	be	VBZ
cord-271972-qhr6iir6	53	10	not	not	RB
cord-271972-qhr6iir6	53	11	sufficient	sufficient	JJ
cord-271972-qhr6iir6	53	12	to	to	TO
cord-271972-qhr6iir6	53	13	recapitulate	recapitulate	VB
cord-271972-qhr6iir6	53	14	the	the	DT
cord-271972-qhr6iir6	53	15	effects	effect	NNS
cord-271972-qhr6iir6	53	16	of	of	IN
cord-271972-qhr6iir6	53	17	PAN	PAN	NNP
cord-271972-qhr6iir6	53	18	-	-	HYPH
cord-271972-qhr6iir6	53	19	ENE	ENE	NNP
cord-271972-qhr6iir6	53	20	,	,	,
cord-271972-qhr6iir6	53	21	6	6	CD
cord-271972-qhr6iir6	53	22	and	and	CC
cord-271972-qhr6iir6	53	23	mutations	mutation	NNS
cord-271972-qhr6iir6	53	24	in	in	IN
cord-271972-qhr6iir6	53	25	the	the	DT
cord-271972-qhr6iir6	53	26	stem	stem	NN
cord-271972-qhr6iir6	53	27	region	region	NN
cord-271972-qhr6iir6	53	28	of	of	IN
cord-271972-qhr6iir6	53	29	PAN	PAN	NNP
cord-271972-qhr6iir6	53	30	-	-	HYPH
cord-271972-qhr6iir6	53	31	ENE	ENE	NNP
cord-271972-qhr6iir6	53	32	can	can	MD
cord-271972-qhr6iir6	53	33	also	also	RB
cord-271972-qhr6iir6	53	34	abolish	abolish	VB
cord-271972-qhr6iir6	53	35	its	-PRON-	PRP$
cord-271972-qhr6iir6	53	36	function	function	NN
cord-271972-qhr6iir6	53	37	.	.	.
cord-271972-qhr6iir6	54	1	7	7	CD
cord-271972-qhr6iir6	55	1	These	these	DT
cord-271972-qhr6iir6	55	2	observations	observation	NNS
cord-271972-qhr6iir6	55	3	suggest	suggest	VBP
cord-271972-qhr6iir6	55	4	that	that	IN
cord-271972-qhr6iir6	55	5	the	the	DT
cord-271972-qhr6iir6	55	6	entire	entire	JJ
cord-271972-qhr6iir6	55	7	structure	structure	NN
cord-271972-qhr6iir6	55	8	is	be	VBZ
cord-271972-qhr6iir6	55	9	required	require	VBN
cord-271972-qhr6iir6	55	10	for	for	IN
cord-271972-qhr6iir6	55	11	efficient	efficient	JJ
cord-271972-qhr6iir6	55	12	interaction	interaction	NN
cord-271972-qhr6iir6	55	13	and	and	CC
cord-271972-qhr6iir6	55	14	potentially	potentially	RB
cord-271972-qhr6iir6	55	15	for	for	IN
cord-271972-qhr6iir6	55	16	the	the	DT
cord-271972-qhr6iir6	55	17	recruitment	recruitment	NN
cord-271972-qhr6iir6	55	18	of	of	IN
cord-271972-qhr6iir6	55	19	additional	additional	JJ
cord-271972-qhr6iir6	55	20	protective	protective	JJ
cord-271972-qhr6iir6	55	21	factors	factor	NNS
cord-271972-qhr6iir6	55	22	.	.	.
cord-271972-qhr6iir6	56	1	As	as	IN
cord-271972-qhr6iir6	56	2	the	the	DT
cord-271972-qhr6iir6	56	3	function	function	NN
cord-271972-qhr6iir6	56	4	of	of	IN
cord-271972-qhr6iir6	56	5	PAN	PAN	NNP
cord-271972-qhr6iir6	56	6	remains	remain	VBZ
cord-271972-qhr6iir6	56	7	unknown	unknown	JJ
cord-271972-qhr6iir6	56	8	,	,	,
cord-271972-qhr6iir6	56	9	at	at	IN
cord-271972-qhr6iir6	56	10	present	present	JJ
cord-271972-qhr6iir6	56	11	the	the	DT
cord-271972-qhr6iir6	56	12	importance	importance	NN
cord-271972-qhr6iir6	56	13	of	of	IN
cord-271972-qhr6iir6	56	14	the	the	DT
cord-271972-qhr6iir6	56	15	PAN	PAN	NNP
cord-271972-qhr6iir6	56	16	-	-	HYPH
cord-271972-qhr6iir6	56	17	ENE	ENE	NNP
cord-271972-qhr6iir6	56	18	in	in	IN
cord-271972-qhr6iir6	56	19	KSHV	KSHV	NNP
cord-271972-qhr6iir6	56	20	infection	infection	NN
cord-271972-qhr6iir6	56	21	can	can	MD
cord-271972-qhr6iir6	56	22	not	not	RB
cord-271972-qhr6iir6	56	23	be	be	VB
cord-271972-qhr6iir6	56	24	assessed	assess	VBN
cord-271972-qhr6iir6	56	25	.	.	.
cord-271972-qhr6iir6	57	1	The	the	DT
cord-271972-qhr6iir6	57	2	fact	fact	NN
cord-271972-qhr6iir6	57	3	that	that	IN
cord-271972-qhr6iir6	57	4	the	the	DT
cord-271972-qhr6iir6	57	5	decay	decay	NN
cord-271972-qhr6iir6	57	6	kinetics	kinetic	NNS
cord-271972-qhr6iir6	57	7	of	of	IN
cord-271972-qhr6iir6	57	8	PAN	PAN	NNP
cord-271972-qhr6iir6	57	9	are	be	VBP
cord-271972-qhr6iir6	57	10	different	different	JJ
cord-271972-qhr6iir6	57	11	from	from	IN
cord-271972-qhr6iir6	57	12	those	those	DT
cord-271972-qhr6iir6	57	13	of	of	IN
cord-271972-qhr6iir6	57	14	cytoplasmic	cytoplasmic	JJ
cord-271972-qhr6iir6	57	15	polyadenylated	polyadenylated	JJ
cord-271972-qhr6iir6	57	16	RNAs	rna	NNS
cord-271972-qhr6iir6	57	17	has	have	VBZ
cord-271972-qhr6iir6	57	18	led	lead	VBN
cord-271972-qhr6iir6	57	19	to	to	IN
cord-271972-qhr6iir6	57	20	the	the	DT
cord-271972-qhr6iir6	57	21	speculation	speculation	NN
cord-271972-qhr6iir6	57	22	that	that	IN
cord-271972-qhr6iir6	57	23	PAN	PAN	NNP
cord-271972-qhr6iir6	57	24	RNA	RNA	NNP
cord-271972-qhr6iir6	57	25	degradation	degradation	NN
cord-271972-qhr6iir6	57	26	,	,	,
cord-271972-qhr6iir6	57	27	particularly	particularly	RB
cord-271972-qhr6iir6	57	28	at	at	IN
cord-271972-qhr6iir6	57	29	the	the	DT
cord-271972-qhr6iir6	57	30	stage	stage	NN
cord-271972-qhr6iir6	57	31	of	of	IN
cord-271972-qhr6iir6	57	32	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	57	33	,	,	,
cord-271972-qhr6iir6	57	34	may	may	MD
cord-271972-qhr6iir6	57	35	be	be	VB
cord-271972-qhr6iir6	57	36	carried	carry	VBN
cord-271972-qhr6iir6	57	37	out	out	RP
cord-271972-qhr6iir6	57	38	by	by	IN
cord-271972-qhr6iir6	57	39	a	a	DT
cord-271972-qhr6iir6	57	40	dedicated	dedicated	JJ
cord-271972-qhr6iir6	57	41	nuclear	nuclear	JJ
cord-271972-qhr6iir6	57	42	pathway	pathway	NN
cord-271972-qhr6iir6	57	43	that	that	WDT
cord-271972-qhr6iir6	57	44	normally	normally	RB
cord-271972-qhr6iir6	57	45	disposes	dispose	VBZ
cord-271972-qhr6iir6	57	46	of	of	IN
cord-271972-qhr6iir6	57	47	incorrectly	incorrectly	RB
cord-271972-qhr6iir6	57	48	processed	process	VBN
cord-271972-qhr6iir6	57	49	RNAs	rna	NNS
cord-271972-qhr6iir6	57	50	.	.	.
cord-271972-qhr6iir6	58	1	6	6	CD
cord-271972-qhr6iir6	59	1	Thus	thus	RB
cord-271972-qhr6iir6	59	2	,	,	,
cord-271972-qhr6iir6	59	3	the	the	DT
cord-271972-qhr6iir6	59	4	study	study	NN
cord-271972-qhr6iir6	59	5	of	of	IN
cord-271972-qhr6iir6	59	6	PAN	PAN	NNP
cord-271972-qhr6iir6	59	7	RNA	RNA	NNP
cord-271972-qhr6iir6	59	8	protection	protection	NN
cord-271972-qhr6iir6	59	9	from	from	IN
cord-271972-qhr6iir6	59	10	nuclear	nuclear	JJ
cord-271972-qhr6iir6	59	11	degradation	degradation	NN
cord-271972-qhr6iir6	59	12	may	may	MD
cord-271972-qhr6iir6	59	13	provide	provide	VB
cord-271972-qhr6iir6	59	14	information	information	NN
cord-271972-qhr6iir6	59	15	as	as	IN
cord-271972-qhr6iir6	59	16	to	to	IN
cord-271972-qhr6iir6	59	17	how	how	WRB
cord-271972-qhr6iir6	59	18	polyadenylation	polyadenylation	NN
cord-271972-qhr6iir6	59	19	and	and	CC
cord-271972-qhr6iir6	59	20	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	59	21	are	be	VBP
cord-271972-qhr6iir6	59	22	carried	carry	VBN
cord-271972-qhr6iir6	59	23	out	out	RP
cord-271972-qhr6iir6	59	24	in	in	IN
cord-271972-qhr6iir6	59	25	the	the	DT
cord-271972-qhr6iir6	59	26	nucleus	nucleus	NN
cord-271972-qhr6iir6	59	27	of	of	IN
cord-271972-qhr6iir6	59	28	mammalian	mammalian	JJ
cord-271972-qhr6iir6	59	29	cells	cell	NNS
cord-271972-qhr6iir6	59	30	and	and	CC
cord-271972-qhr6iir6	59	31	how	how	WRB
cord-271972-qhr6iir6	59	32	they	-PRON-	PRP
cord-271972-qhr6iir6	59	33	contribute	contribute	VBP
cord-271972-qhr6iir6	59	34	to	to	IN
cord-271972-qhr6iir6	59	35	nuclear	nuclear	JJ
cord-271972-qhr6iir6	59	36	RNA	RNA	NNP
cord-271972-qhr6iir6	59	37	quality	quality	NN
cord-271972-qhr6iir6	59	38	control	control	NN
cord-271972-qhr6iir6	59	39	.	.	.
cord-271972-qhr6iir6	60	1	As	as	IN
cord-271972-qhr6iir6	60	2	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	60	3	is	be	VBZ
cord-271972-qhr6iir6	60	4	completed	complete	VBN
cord-271972-qhr6iir6	60	5	,	,	,
cord-271972-qhr6iir6	60	6	a	a	DT
cord-271972-qhr6iir6	60	7	ring	ring	NN
cord-271972-qhr6iir6	60	8	-	-	HYPH
cord-271972-qhr6iir6	60	9	shaped	shape	VBN
cord-271972-qhr6iir6	60	10	heptameric	heptameric	NN
cord-271972-qhr6iir6	60	11	complex	complex	NN
cord-271972-qhr6iir6	60	12	of	of	IN
cord-271972-qhr6iir6	60	13	Sm	sm	NN
cord-271972-qhr6iir6	60	14	-	-	HYPH
cord-271972-qhr6iir6	60	15	like	like	JJ
cord-271972-qhr6iir6	60	16	proteins	protein	NNS
cord-271972-qhr6iir6	61	1	(	(	-LRB-
cord-271972-qhr6iir6	61	2	Lsm1	Lsm1	NNP
cord-271972-qhr6iir6	61	3	-	-	HYPH
cord-271972-qhr6iir6	61	4	7	7	NNP
cord-271972-qhr6iir6	61	5	)	)	-RRB-
cord-271972-qhr6iir6	61	6	binds	bind	VBZ
cord-271972-qhr6iir6	61	7	to	to	IN
cord-271972-qhr6iir6	61	8	the	the	DT
cord-271972-qhr6iir6	61	9	3	3	CD
cord-271972-qhr6iir6	61	10	end	end	NN
cord-271972-qhr6iir6	61	11	of	of	IN
cord-271972-qhr6iir6	61	12	the	the	DT
cord-271972-qhr6iir6	61	13	message	message	NN
cord-271972-qhr6iir6	61	14	and	and	CC
cord-271972-qhr6iir6	61	15	recruits	recruit	VBZ
cord-271972-qhr6iir6	61	16	the	the	DT
cord-271972-qhr6iir6	61	17	cellular	cellular	JJ
cord-271972-qhr6iir6	61	18	decapping	decapping	NN
cord-271972-qhr6iir6	61	19	enzymes	enzyme	NNS
cord-271972-qhr6iir6	61	20	Dcp1	Dcp1	NNP
cord-271972-qhr6iir6	61	21	and	and	CC
cord-271972-qhr6iir6	61	22	Dcp2	Dcp2	NNP
cord-271972-qhr6iir6	61	23	,	,	,
cord-271972-qhr6iir6	61	24	which	which	WDT
cord-271972-qhr6iir6	61	25	promote	promote	VBP
cord-271972-qhr6iir6	61	26	cap	cap	NN
cord-271972-qhr6iir6	61	27	hydrolysis	hydrolysis	NN
cord-271972-qhr6iir6	61	28	[	[	-LRB-
cord-271972-qhr6iir6	61	29	8	8	CD
cord-271972-qhr6iir6	61	30	]	]	-RRB-
cord-271972-qhr6iir6	62	1	[	[	-LRB-
cord-271972-qhr6iir6	62	2	9	9	CD
cord-271972-qhr6iir6	62	3	]	]	-RRB-
cord-271972-qhr6iir6	62	4	[	[	-LRB-
cord-271972-qhr6iir6	62	5	10	10	CD
cord-271972-qhr6iir6	62	6	]	]	-RRB-
cord-271972-qhr6iir6	63	1	[	[	-LRB-
cord-271972-qhr6iir6	63	2	11	11	CD
cord-271972-qhr6iir6	63	3	]	]	-RRB-
cord-271972-qhr6iir6	63	4	(	(	-LRB-
cord-271972-qhr6iir6	63	5	Figure	figure	NN
cord-271972-qhr6iir6	63	6	1	1	CD
cord-271972-qhr6iir6	63	7	)	)	-RRB-
cord-271972-qhr6iir6	63	8	.	.	.
cord-271972-qhr6iir6	64	1	The	the	DT
cord-271972-qhr6iir6	64	2	Lsm	Lsm	NNP
cord-271972-qhr6iir6	64	3	complex	complex	NN
cord-271972-qhr6iir6	64	4	is	be	VBZ
cord-271972-qhr6iir6	64	5	highly	highly	RB
cord-271972-qhr6iir6	64	6	conserved	conserve	VBN
cord-271972-qhr6iir6	64	7	in	in	IN
cord-271972-qhr6iir6	64	8	eukaryotes	eukaryote	NNS
cord-271972-qhr6iir6	64	9	,	,	,
cord-271972-qhr6iir6	64	10	and	and	CC
cord-271972-qhr6iir6	64	11	in	in	IN
cord-271972-qhr6iir6	64	12	yeast	yeast	NN
cord-271972-qhr6iir6	64	13	it	-PRON-	PRP
cord-271972-qhr6iir6	64	14	has	have	VBZ
cord-271972-qhr6iir6	64	15	been	be	VBN
cord-271972-qhr6iir6	64	16	shown	show	VBN
cord-271972-qhr6iir6	64	17	to	to	TO
cord-271972-qhr6iir6	64	18	associate	associate	VB
cord-271972-qhr6iir6	64	19	with	with	IN
cord-271972-qhr6iir6	64	20	several	several	JJ
cord-271972-qhr6iir6	64	21	additional	additional	JJ
cord-271972-qhr6iir6	64	22	components	component	NNS
cord-271972-qhr6iir6	64	23	of	of	IN
cord-271972-qhr6iir6	64	24	the	the	DT
cord-271972-qhr6iir6	64	25	RNA	RNA	NNP
cord-271972-qhr6iir6	64	26	decay	decay	NN
cord-271972-qhr6iir6	64	27	machinery	machinery	NN
cord-271972-qhr6iir6	64	28	,	,	,
cord-271972-qhr6iir6	64	29	including	include	VBG
cord-271972-qhr6iir6	64	30	decapping	decappe	VBG
cord-271972-qhr6iir6	64	31	activators	activator	NNS
cord-271972-qhr6iir6	64	32	and	and	CC
cord-271972-qhr6iir6	64	33	the	the	DT
cord-271972-qhr6iir6	64	34	5	5	CD
cord-271972-qhr6iir6	64	35	→3	→3	NNS
cord-271972-qhr6iir6	64	36	exonuclease	exonuclease	NN
cord-271972-qhr6iir6	64	37	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	64	38	.	.	.
cord-271972-qhr6iir6	65	1	[	[	-LRB-
cord-271972-qhr6iir6	65	2	10	10	CD
cord-271972-qhr6iir6	65	3	]	]	-RRB-
cord-271972-qhr6iir6	65	4	[	[	-LRB-
cord-271972-qhr6iir6	65	5	11	11	CD
cord-271972-qhr6iir6	65	6	]	]	-RRB-
cord-271972-qhr6iir6	65	7	[	[	-LRB-
cord-271972-qhr6iir6	65	8	12	12	CD
cord-271972-qhr6iir6	65	9	]	]	-RRB-
cord-271972-qhr6iir6	65	10	[	[	-LRB-
cord-271972-qhr6iir6	65	11	13	13	CD
cord-271972-qhr6iir6	65	12	]	]	-RRB-
cord-271972-qhr6iir6	66	1	[	[	-LRB-
cord-271972-qhr6iir6	66	2	14	14	CD
cord-271972-qhr6iir6	66	3	]	]	-RRB-
cord-271972-qhr6iir6	67	1	While	while	IN
cord-271972-qhr6iir6	67	2	the	the	DT
cord-271972-qhr6iir6	67	3	role	role	NN
cord-271972-qhr6iir6	67	4	of	of	IN
cord-271972-qhr6iir6	67	5	the	the	DT
cord-271972-qhr6iir6	67	6	Lsm	Lsm	NNP
cord-271972-qhr6iir6	67	7	proteins	protein	NNS
cord-271972-qhr6iir6	67	8	in	in	IN
cord-271972-qhr6iir6	67	9	eukaryotes	eukaryote	NNS
cord-271972-qhr6iir6	67	10	is	be	VBZ
cord-271972-qhr6iir6	67	11	closely	closely	RB
cord-271972-qhr6iir6	67	12	linked	link	VBN
cord-271972-qhr6iir6	67	13	to	to	IN
cord-271972-qhr6iir6	67	14	mRNA	mRNA	NNP
cord-271972-qhr6iir6	67	15	degradation	degradation	NN
cord-271972-qhr6iir6	67	16	,	,	,
cord-271972-qhr6iir6	67	17	several	several	JJ
cord-271972-qhr6iir6	67	18	viruses	virus	NNS
cord-271972-qhr6iir6	67	19	use	use	VBP
cord-271972-qhr6iir6	67	20	this	this	DT
cord-271972-qhr6iir6	67	21	complex	complex	NN
cord-271972-qhr6iir6	67	22	instead	instead	RB
cord-271972-qhr6iir6	67	23	to	to	TO
cord-271972-qhr6iir6	67	24	facilitate	facilitate	VB
cord-271972-qhr6iir6	67	25	viral	viral	JJ
cord-271972-qhr6iir6	67	26	replication	replication	NN
cord-271972-qhr6iir6	67	27	and	and	CC
cord-271972-qhr6iir6	67	28	,	,	,
cord-271972-qhr6iir6	67	29	surprisingly	surprisingly	RB
cord-271972-qhr6iir6	67	30	,	,	,
cord-271972-qhr6iir6	67	31	to	to	TO
cord-271972-qhr6iir6	67	32	enhance	enhance	VB
cord-271972-qhr6iir6	67	33	viral	viral	JJ
cord-271972-qhr6iir6	67	34	RNA	rna	NN
cord-271972-qhr6iir6	67	35	stability	stability	NN
cord-271972-qhr6iir6	67	36	.	.	.
cord-271972-qhr6iir6	68	1	The	the	DT
cord-271972-qhr6iir6	68	2	Lsm	Lsm	NNP
cord-271972-qhr6iir6	68	3	complex	complex	NN
cord-271972-qhr6iir6	68	4	has	have	VBZ
cord-271972-qhr6iir6	68	5	been	be	VBN
cord-271972-qhr6iir6	68	6	shown	show	VBN
cord-271972-qhr6iir6	68	7	to	to	TO
cord-271972-qhr6iir6	68	8	participate	participate	VB
cord-271972-qhr6iir6	68	9	in	in	IN
cord-271972-qhr6iir6	68	10	both	both	DT
cord-271972-qhr6iir6	68	11	viral	viral	JJ
cord-271972-qhr6iir6	68	12	replication	replication	NN
cord-271972-qhr6iir6	68	13	and	and	CC
cord-271972-qhr6iir6	68	14	translation	translation	NN
cord-271972-qhr6iir6	68	15	of	of	IN
cord-271972-qhr6iir6	68	16	Brome	Brome	NNP
cord-271972-qhr6iir6	68	17	mosaic	mosaic	JJ
cord-271972-qhr6iir6	68	18	virus	virus	NN
cord-271972-qhr6iir6	68	19	(	(	-LRB-
cord-271972-qhr6iir6	68	20	BMV	BMV	NNP
cord-271972-qhr6iir6	68	21	)	)	-RRB-
cord-271972-qhr6iir6	68	22	[	[	-LRB-
cord-271972-qhr6iir6	68	23	15	15	CD
cord-271972-qhr6iir6	68	24	]	]	-RRB-
cord-271972-qhr6iir6	68	25	[	[	-LRB-
cord-271972-qhr6iir6	68	26	16	16	CD
cord-271972-qhr6iir6	68	27	]	]	-RRB-
cord-271972-qhr6iir6	68	28	[	[	-LRB-
cord-271972-qhr6iir6	68	29	17	17	CD
cord-271972-qhr6iir6	68	30	]	]	-RRB-
cord-271972-qhr6iir6	68	31	and	and	CC
cord-271972-qhr6iir6	68	32	hepatitis	hepatitis	NNP
cord-271972-qhr6iir6	68	33	C	C	NNP
cord-271972-qhr6iir6	68	34	virus	virus	NN
cord-271972-qhr6iir6	68	35	(	(	-LRB-
cord-271972-qhr6iir6	68	36	HCV	HCV	NNP
cord-271972-qhr6iir6	68	37	)	)	-RRB-
cord-271972-qhr6iir6	68	38	18	18	CD
cord-271972-qhr6iir6	68	39	(	(	-LRB-
cord-271972-qhr6iir6	68	40	Figure	figure	NN
cord-271972-qhr6iir6	68	41	2(b	2(b	CD
cord-271972-qhr6iir6	68	42	)	)	-RRB-
cord-271972-qhr6iir6	68	43	)	)	-RRB-
cord-271972-qhr6iir6	68	44	.	.	.
cord-271972-qhr6iir6	69	1	Like	like	IN
cord-271972-qhr6iir6	69	2	those	those	DT
cord-271972-qhr6iir6	69	3	of	of	IN
cord-271972-qhr6iir6	69	4	all	all	DT
cord-271972-qhr6iir6	69	5	other	other	JJ
cord-271972-qhr6iir6	69	6	(	(	-LRB-
cord-271972-qhr6iir6	69	7	+	+	CD
cord-271972-qhr6iir6	69	8	)	)	-RRB-
cord-271972-qhr6iir6	69	9	RNA	RNA	NNP
cord-271972-qhr6iir6	69	10	viruses	virus	NNS
cord-271972-qhr6iir6	69	11	,	,	,
cord-271972-qhr6iir6	69	12	the	the	DT
cord-271972-qhr6iir6	69	13	genomes	genome	NNS
cord-271972-qhr6iir6	69	14	of	of	IN
cord-271972-qhr6iir6	69	15	BMV	BMV	NNP
cord-271972-qhr6iir6	69	16	and	and	CC
cord-271972-qhr6iir6	69	17	HCV	HCV	NNP
cord-271972-qhr6iir6	69	18	are	be	VBP
cord-271972-qhr6iir6	69	19	used	use	VBN
cord-271972-qhr6iir6	69	20	first	first	RB
cord-271972-qhr6iir6	69	21	as	as	IN
cord-271972-qhr6iir6	69	22	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	69	23	for	for	IN
cord-271972-qhr6iir6	69	24	protein	protein	NN
cord-271972-qhr6iir6	69	25	production	production	NN
cord-271972-qhr6iir6	69	26	,	,	,
cord-271972-qhr6iir6	69	27	and	and	CC
cord-271972-qhr6iir6	69	28	subsequently	subsequently	RB
cord-271972-qhr6iir6	69	29	as	as	IN
cord-271972-qhr6iir6	69	30	templates	template	NNS
cord-271972-qhr6iir6	69	31	for	for	IN
cord-271972-qhr6iir6	69	32	replication	replication	NN
cord-271972-qhr6iir6	69	33	.	.	.
cord-271972-qhr6iir6	70	1	These	these	DT
cord-271972-qhr6iir6	70	2	two	two	CD
cord-271972-qhr6iir6	70	3	processes	process	NNS
cord-271972-qhr6iir6	70	4	are	be	VBP
cord-271972-qhr6iir6	70	5	considered	consider	VBN
cord-271972-qhr6iir6	70	6	mutually	mutually	RB
cord-271972-qhr6iir6	70	7	exclusive	exclusive	JJ
cord-271972-qhr6iir6	70	8	and	and	CC
cord-271972-qhr6iir6	70	9	often	often	RB
cord-271972-qhr6iir6	70	10	require	require	VBP
cord-271972-qhr6iir6	70	11	different	different	JJ
cord-271972-qhr6iir6	70	12	cis	cis	NNP
cord-271972-qhr6iir6	70	13	-	-	HYPH
cord-271972-qhr6iir6	70	14	acting	acting	NN
cord-271972-qhr6iir6	70	15	sequences	sequence	NNS
cord-271972-qhr6iir6	70	16	.	.	.
cord-271972-qhr6iir6	71	1	The	the	DT
cord-271972-qhr6iir6	71	2	genome	genome	NN
cord-271972-qhr6iir6	71	3	of	of	IN
cord-271972-qhr6iir6	71	4	BMV	BMV	NNP
cord-271972-qhr6iir6	71	5	consists	consist	VBZ
cord-271972-qhr6iir6	71	6	of	of	IN
cord-271972-qhr6iir6	71	7	three	three	CD
cord-271972-qhr6iir6	71	8	RNA	RNA	NNP
cord-271972-qhr6iir6	71	9	segments	segment	NNS
cord-271972-qhr6iir6	71	10	that	that	WDT
cord-271972-qhr6iir6	71	11	are	be	VBP
cord-271972-qhr6iir6	71	12	5	5	CD
cord-271972-qhr6iir6	71	13	capped	cap	VBN
cord-271972-qhr6iir6	71	14	,	,	,
cord-271972-qhr6iir6	71	15	but	but	CC
cord-271972-qhr6iir6	71	16	terminate	terminate	VB
cord-271972-qhr6iir6	71	17	in	in	IN
cord-271972-qhr6iir6	71	18	a	a	DT
cord-271972-qhr6iir6	71	19	3	3	CD
cord-271972-qhr6iir6	71	20	tRNA	trna	NN
cord-271972-qhr6iir6	71	21	-	-	HYPH
cord-271972-qhr6iir6	71	22	like	like	JJ
cord-271972-qhr6iir6	71	23	structure	structure	NN
cord-271972-qhr6iir6	71	24	rather	rather	RB
cord-271972-qhr6iir6	71	25	than	than	IN
cord-271972-qhr6iir6	71	26	a	a	DT
cord-271972-qhr6iir6	71	27	poly(A	poly(a	JJ
cord-271972-qhr6iir6	71	28	)	)	-RRB-
cord-271972-qhr6iir6	71	29	tail	tail	NN
cord-271972-qhr6iir6	71	30	.	.	.
cord-271972-qhr6iir6	72	1	Although	although	IN
cord-271972-qhr6iir6	72	2	plants	plant	NNS
cord-271972-qhr6iir6	72	3	are	be	VBP
cord-271972-qhr6iir6	72	4	its	-PRON-	PRP$
cord-271972-qhr6iir6	72	5	natural	natural	JJ
cord-271972-qhr6iir6	72	6	host	host	NN
cord-271972-qhr6iir6	72	7	,	,	,
cord-271972-qhr6iir6	72	8	BMV	BMV	NNP
cord-271972-qhr6iir6	72	9	can	can	MD
cord-271972-qhr6iir6	72	10	also	also	RB
cord-271972-qhr6iir6	72	11	replicate	replicate	VB
cord-271972-qhr6iir6	72	12	in	in	IN
cord-271972-qhr6iir6	72	13	yeast	yeast	NN
cord-271972-qhr6iir6	72	14	,	,	,
cord-271972-qhr6iir6	72	15	which	which	WDT
cord-271972-qhr6iir6	72	16	has	have	VBZ
cord-271972-qhr6iir6	72	17	greatly	greatly	RB
cord-271972-qhr6iir6	72	18	facilitated	facilitate	VBN
cord-271972-qhr6iir6	72	19	genetic	genetic	JJ
cord-271972-qhr6iir6	72	20	dissection	dissection	NN
cord-271972-qhr6iir6	72	21	of	of	IN
cord-271972-qhr6iir6	72	22	host	host	NN
cord-271972-qhr6iir6	72	23	factors	factor	NNS
cord-271972-qhr6iir6	72	24	involved	involve	VBN
cord-271972-qhr6iir6	72	25	in	in	IN
cord-271972-qhr6iir6	72	26	its	-PRON-	PRP$
cord-271972-qhr6iir6	72	27	replication	replication	NN
cord-271972-qhr6iir6	72	28	cycle	cycle	NN
cord-271972-qhr6iir6	72	29	.	.	.
cord-271972-qhr6iir6	73	1	A	a	DT
cord-271972-qhr6iir6	73	2	mutagenesis	mutagenesis	NN
cord-271972-qhr6iir6	73	3	screen	screen	NN
cord-271972-qhr6iir6	73	4	in	in	IN
cord-271972-qhr6iir6	73	5	yeast	yeast	NN
cord-271972-qhr6iir6	73	6	identified	identify	VBN
cord-271972-qhr6iir6	73	7	Lsm1p	Lsm1p	NNPS
cord-271972-qhr6iir6	73	8	as	as	IN
cord-271972-qhr6iir6	73	9	a	a	DT
cord-271972-qhr6iir6	73	10	host	host	NN
cord-271972-qhr6iir6	73	11	factor	factor	NN
cord-271972-qhr6iir6	73	12	required	require	VBN
cord-271972-qhr6iir6	73	13	for	for	IN
cord-271972-qhr6iir6	73	14	BMV	BMV	NNP
cord-271972-qhr6iir6	73	15	RNA	RNA	NNP
cord-271972-qhr6iir6	73	16	replication	replication	NN
cord-271972-qhr6iir6	73	17	.	.	.
cord-271972-qhr6iir6	74	1	15	15	CD
cord-271972-qhr6iir6	75	1	Subsequent	subsequent	JJ
cord-271972-qhr6iir6	75	2	studies	study	NNS
cord-271972-qhr6iir6	75	3	showed	show	VBD
cord-271972-qhr6iir6	75	4	that	that	IN
cord-271972-qhr6iir6	75	5	Lsm1p	Lsm1p	NNPS
cord-271972-qhr6iir6	75	6	,	,	,
cord-271972-qhr6iir6	75	7	together	together	RB
cord-271972-qhr6iir6	75	8	with	with	IN
cord-271972-qhr6iir6	75	9	other	other	JJ
cord-271972-qhr6iir6	75	10	components	component	NNS
cord-271972-qhr6iir6	75	11	of	of	IN
cord-271972-qhr6iir6	75	12	the	the	DT
cord-271972-qhr6iir6	75	13	Lsm	Lsm	NNP
cord-271972-qhr6iir6	75	14	complex	complex	NN
cord-271972-qhr6iir6	75	15	,	,	,
cord-271972-qhr6iir6	75	16	is	be	VBZ
cord-271972-qhr6iir6	75	17	also	also	RB
cord-271972-qhr6iir6	75	18	required	require	VBN
cord-271972-qhr6iir6	75	19	for	for	IN
cord-271972-qhr6iir6	75	20	efficient	efficient	JJ
cord-271972-qhr6iir6	75	21	BMV	BMV	NNP
cord-271972-qhr6iir6	75	22	genomic	genomic	JJ
cord-271972-qhr6iir6	75	23	RNA	rna	NN
cord-271972-qhr6iir6	75	24	translation	translation	NN
cord-271972-qhr6iir6	75	25	elongation	elongation	NN
cord-271972-qhr6iir6	75	26	,	,	,
cord-271972-qhr6iir6	75	27	but	but	CC
cord-271972-qhr6iir6	75	28	not	not	RB
cord-271972-qhr6iir6	75	29	initiation	initiation	NN
cord-271972-qhr6iir6	75	30	.	.	.
cord-271972-qhr6iir6	76	1	17	17	CD
cord-271972-qhr6iir6	77	1	While	while	IN
cord-271972-qhr6iir6	77	2	Lsm	Lsm	NNP
cord-271972-qhr6iir6	77	3	-	-	HYPH
cord-271972-qhr6iir6	77	4	stimulated	stimulate	VBN
cord-271972-qhr6iir6	77	5	BMV	BMV	NNP
cord-271972-qhr6iir6	77	6	translation	translation	NN
cord-271972-qhr6iir6	77	7	requires	require	VBZ
cord-271972-qhr6iir6	77	8	multiple	multiple	JJ
cord-271972-qhr6iir6	77	9	regions	region	NNS
cord-271972-qhr6iir6	77	10	of	of	IN
cord-271972-qhr6iir6	77	11	the	the	DT
cord-271972-qhr6iir6	77	12	viral	viral	JJ
cord-271972-qhr6iir6	77	13	RNAs	rna	NNS
cord-271972-qhr6iir6	77	14	,	,	,
cord-271972-qhr6iir6	77	15	the	the	DT
cord-271972-qhr6iir6	77	16	effect	effect	NN
cord-271972-qhr6iir6	77	17	of	of	IN
cord-271972-qhr6iir6	77	18	Lsm	Lsm	NNP
cord-271972-qhr6iir6	77	19	on	on	IN
cord-271972-qhr6iir6	77	20	BMV	BMV	NNP
cord-271972-qhr6iir6	77	21	RNA	RNA	NNP
cord-271972-qhr6iir6	77	22	replication	replication	NN
cord-271972-qhr6iir6	77	23	is	be	VBZ
cord-271972-qhr6iir6	77	24	specifically	specifically	RB
cord-271972-qhr6iir6	77	25	dependent	dependent	JJ
cord-271972-qhr6iir6	77	26	on	on	IN
cord-271972-qhr6iir6	77	27	3	3	CD
cord-271972-qhr6iir6	77	28	UTR	UTR	NNP
cord-271972-qhr6iir6	77	29	elements	element	NNS
cord-271972-qhr6iir6	77	30	.	.	.
cord-271972-qhr6iir6	78	1	16	16	CD
cord-271972-qhr6iir6	78	2	,	,	,
cord-271972-qhr6iir6	78	3	17	17	CD
cord-271972-qhr6iir6	79	1	Thus	thus	RB
cord-271972-qhr6iir6	79	2	,	,	,
cord-271972-qhr6iir6	79	3	partially	partially	RB
cord-271972-qhr6iir6	79	4	overlapping	overlap	VBG
cord-271972-qhr6iir6	79	5	signals	signal	NNS
cord-271972-qhr6iir6	79	6	appear	appear	VBP
cord-271972-qhr6iir6	79	7	to	to	TO
cord-271972-qhr6iir6	79	8	participate	participate	VB
cord-271972-qhr6iir6	79	9	in	in	IN
cord-271972-qhr6iir6	79	10	the	the	DT
cord-271972-qhr6iir6	79	11	seemingly	seemingly	RB
cord-271972-qhr6iir6	79	12	opposing	opposing	JJ
cord-271972-qhr6iir6	79	13	activities	activity	NNS
cord-271972-qhr6iir6	79	14	of	of	IN
cord-271972-qhr6iir6	79	15	translational	translational	JJ
cord-271972-qhr6iir6	79	16	enhancement	enhancement	NN
cord-271972-qhr6iir6	79	17	and	and	CC
cord-271972-qhr6iir6	79	18	redirection	redirection	NN
cord-271972-qhr6iir6	79	19	of	of	IN
cord-271972-qhr6iir6	79	20	RNAs	rna	NNS
cord-271972-qhr6iir6	79	21	from	from	IN
cord-271972-qhr6iir6	79	22	the	the	DT
cord-271972-qhr6iir6	79	23	translational	translational	JJ
cord-271972-qhr6iir6	79	24	pool	pool	NN
cord-271972-qhr6iir6	79	25	into	into	IN
cord-271972-qhr6iir6	79	26	replication	replication	NN
cord-271972-qhr6iir6	79	27	complexes	complex	NNS
cord-271972-qhr6iir6	79	28	.	.	.
cord-271972-qhr6iir6	80	1	Notably	notably	RB
cord-271972-qhr6iir6	80	2	,	,	,
cord-271972-qhr6iir6	80	3	Lsm	Lsm	NNP
cord-271972-qhr6iir6	80	4	proteins	protein	NNS
cord-271972-qhr6iir6	80	5	do	do	VBP
cord-271972-qhr6iir6	80	6	not	not	RB
cord-271972-qhr6iir6	80	7	regulate	regulate	VB
cord-271972-qhr6iir6	80	8	the	the	DT
cord-271972-qhr6iir6	80	9	translation	translation	NN
cord-271972-qhr6iir6	80	10	of	of	IN
cord-271972-qhr6iir6	80	11	the	the	DT
cord-271972-qhr6iir6	80	12	BMV	BMV	NNP
cord-271972-qhr6iir6	80	13	coat	coat	NN
cord-271972-qhr6iir6	80	14	protein	protein	NN
cord-271972-qhr6iir6	80	15	from	from	IN
cord-271972-qhr6iir6	80	16	a	a	DT
cord-271972-qhr6iir6	80	17	fourth	fourth	JJ
cord-271972-qhr6iir6	80	18	subgenomic	subgenomic	NNP
cord-271972-qhr6iir6	80	19	RNA	RNA	NNP
cord-271972-qhr6iir6	80	20	segment	segment	NN
cord-271972-qhr6iir6	80	21	,	,	,
cord-271972-qhr6iir6	80	22	RNA4	RNA4	NNP
cord-271972-qhr6iir6	80	23	,	,	,
cord-271972-qhr6iir6	80	24	which	which	WDT
cord-271972-qhr6iir6	80	25	is	be	VBZ
cord-271972-qhr6iir6	80	26	generated	generate	VBN
cord-271972-qhr6iir6	80	27	during	during	IN
cord-271972-qhr6iir6	80	28	BMV	BMV	NNP
cord-271972-qhr6iir6	80	29	replication	replication	NN
cord-271972-qhr6iir6	80	30	,	,	,
cord-271972-qhr6iir6	80	31	suggesting	suggest	VBG
cord-271972-qhr6iir6	80	32	that	that	IN
cord-271972-qhr6iir6	80	33	the	the	DT
cord-271972-qhr6iir6	80	34	effects	effect	NNS
cord-271972-qhr6iir6	80	35	of	of	IN
cord-271972-qhr6iir6	80	36	Lsm	Lsm	NNP
cord-271972-qhr6iir6	80	37	proteins	protein	NNS
cord-271972-qhr6iir6	80	38	on	on	IN
cord-271972-qhr6iir6	80	39	BMV	BMV	NNP
cord-271972-qhr6iir6	80	40	RNA	RNA	NNP
cord-271972-qhr6iir6	80	41	translation	translation	NN
cord-271972-qhr6iir6	80	42	and	and	CC
cord-271972-qhr6iir6	80	43	replication	replication	NN
cord-271972-qhr6iir6	80	44	are	be	VBP
cord-271972-qhr6iir6	80	45	tightly	tightly	RB
cord-271972-qhr6iir6	80	46	linked	link	VBN
cord-271972-qhr6iir6	80	47	.	.	.
cord-271972-qhr6iir6	81	1	17	17	CD
cord-271972-qhr6iir6	82	1	As	as	IN
cord-271972-qhr6iir6	82	2	mentioned	mention	VBN
cord-271972-qhr6iir6	82	3	before	before	RB
cord-271972-qhr6iir6	82	4	,	,	,
cord-271972-qhr6iir6	82	5	the	the	DT
cord-271972-qhr6iir6	82	6	Lsm	Lsm	NNP
cord-271972-qhr6iir6	82	7	complex	complex	NN
cord-271972-qhr6iir6	82	8	is	be	VBZ
cord-271972-qhr6iir6	82	9	similarly	similarly	RB
cord-271972-qhr6iir6	82	10	important	important	JJ
cord-271972-qhr6iir6	82	11	for	for	IN
cord-271972-qhr6iir6	82	12	the	the	DT
cord-271972-qhr6iir6	82	13	HCV	HCV	NNP
cord-271972-qhr6iir6	82	14	lifecycle	lifecycle	NN
cord-271972-qhr6iir6	82	15	,	,	,
cord-271972-qhr6iir6	82	16	suggesting	suggest	VBG
cord-271972-qhr6iir6	82	17	that	that	IN
cord-271972-qhr6iir6	82	18	the	the	DT
cord-271972-qhr6iir6	82	19	observations	observation	NNS
cord-271972-qhr6iir6	82	20	on	on	IN
cord-271972-qhr6iir6	82	21	the	the	DT
cord-271972-qhr6iir6	82	22	role	role	NN
cord-271972-qhr6iir6	82	23	of	of	IN
cord-271972-qhr6iir6	82	24	Lsm	Lsm	NNP
cord-271972-qhr6iir6	82	25	in	in	IN
cord-271972-qhr6iir6	82	26	BMV	BMV	NNP
cord-271972-qhr6iir6	82	27	replication	replication	NN
cord-271972-qhr6iir6	82	28	and	and	CC
cord-271972-qhr6iir6	82	29	translation	translation	NN
cord-271972-qhr6iir6	82	30	may	may	MD
cord-271972-qhr6iir6	82	31	generalize	generalize	VB
cord-271972-qhr6iir6	82	32	to	to	IN
cord-271972-qhr6iir6	82	33	many	many	JJ
cord-271972-qhr6iir6	82	34	(	(	-LRB-
cord-271972-qhr6iir6	82	35	+	+	CC
cord-271972-qhr6iir6	82	36	)	)	-RRB-
cord-271972-qhr6iir6	82	37	RNA	RNA	NNP
cord-271972-qhr6iir6	82	38	viruses	virus	NNS
cord-271972-qhr6iir6	82	39	.	.	.
cord-271972-qhr6iir6	83	1	Indeed	indeed	RB
cord-271972-qhr6iir6	83	2	,	,	,
cord-271972-qhr6iir6	83	3	siRNA	sirna	NN
cord-271972-qhr6iir6	83	4	-	-	HYPH
cord-271972-qhr6iir6	83	5	mediated	mediate	VBN
cord-271972-qhr6iir6	83	6	knockdown	knockdown	NN
cord-271972-qhr6iir6	83	7	of	of	IN
cord-271972-qhr6iir6	83	8	Lsm1	Lsm1	NNP
cord-271972-qhr6iir6	83	9	and	and	CC
cord-271972-qhr6iir6	83	10	its	-PRON-	PRP$
cord-271972-qhr6iir6	83	11	co	co	NNS
cord-271972-qhr6iir6	83	12	-	-	NNS
cord-271972-qhr6iir6	83	13	activators	activator	NNS
cord-271972-qhr6iir6	83	14	PatL1	PatL1	NNP
cord-271972-qhr6iir6	83	15	and	and	CC
cord-271972-qhr6iir6	83	16	Rck	Rck	NNP
cord-271972-qhr6iir6	83	17	/	/	SYM
cord-271972-qhr6iir6	83	18	p54	p54	NN
cord-271972-qhr6iir6	83	19	decreases	decrease	VBZ
cord-271972-qhr6iir6	83	20	HCV	HCV	NNP
cord-271972-qhr6iir6	83	21	intracellular	intracellular	JJ
cord-271972-qhr6iir6	83	22	RNA	RNA	NNP
cord-271972-qhr6iir6	83	23	levels	level	NNS
cord-271972-qhr6iir6	83	24	,	,	,
cord-271972-qhr6iir6	83	25	translation	translation	NN
cord-271972-qhr6iir6	83	26	,	,	,
cord-271972-qhr6iir6	83	27	and	and	CC
cord-271972-qhr6iir6	83	28	viral	viral	JJ
cord-271972-qhr6iir6	83	29	particle	particle	NN
cord-271972-qhr6iir6	83	30	production	production	NN
cord-271972-qhr6iir6	83	31	.	.	.
cord-271972-qhr6iir6	84	1	18	18	CD
cord-271972-qhr6iir6	85	1	Using	use	VBG
cord-271972-qhr6iir6	85	2	gel	gel	NN
cord-271972-qhr6iir6	85	3	shift	shift	NN
cord-271972-qhr6iir6	85	4	assays	assay	NNS
cord-271972-qhr6iir6	85	5	,	,	,
cord-271972-qhr6iir6	85	6	the	the	DT
cord-271972-qhr6iir6	85	7	Lsm1	Lsm1	NNP
cord-271972-qhr6iir6	85	8	-	-	HYPH
cord-271972-qhr6iir6	85	9	7	7	CD
cord-271972-qhr6iir6	85	10	ring	ring	NN
cord-271972-qhr6iir6	85	11	was	be	VBD
cord-271972-qhr6iir6	85	12	shown	show	VBN
cord-271972-qhr6iir6	85	13	to	to	TO
cord-271972-qhr6iir6	85	14	interact	interact	VB
cord-271972-qhr6iir6	85	15	with	with	IN
cord-271972-qhr6iir6	85	16	select	select	JJ
cord-271972-qhr6iir6	85	17	HCV	HCV	NNP
cord-271972-qhr6iir6	85	18	5	5	CD
cord-271972-qhr6iir6	85	19	and	and	CC
cord-271972-qhr6iir6	85	20	3	3	CD
cord-271972-qhr6iir6	85	21	UTR	UTR	NNP
cord-271972-qhr6iir6	85	22	sequences	sequence	NNS
cord-271972-qhr6iir6	85	23	necessary	necessary	JJ
cord-271972-qhr6iir6	85	24	for	for	IN
cord-271972-qhr6iir6	85	25	translation	translation	NN
cord-271972-qhr6iir6	85	26	and	and	CC
cord-271972-qhr6iir6	85	27	replication	replication	NN
cord-271972-qhr6iir6	85	28	,	,	,
cord-271972-qhr6iir6	85	29	suggesting	suggest	VBG
cord-271972-qhr6iir6	85	30	that	that	IN
cord-271972-qhr6iir6	85	31	it	-PRON-	PRP
cord-271972-qhr6iir6	85	32	may	may	MD
cord-271972-qhr6iir6	85	33	play	play	VB
cord-271972-qhr6iir6	85	34	a	a	DT
cord-271972-qhr6iir6	85	35	direct	direct	JJ
cord-271972-qhr6iir6	85	36	role	role	NN
cord-271972-qhr6iir6	85	37	in	in	IN
cord-271972-qhr6iir6	85	38	modulating	modulate	VBG
cord-271972-qhr6iir6	85	39	these	these	DT
cord-271972-qhr6iir6	85	40	processes	process	NNS
cord-271972-qhr6iir6	85	41	during	during	IN
cord-271972-qhr6iir6	85	42	infection	infection	NN
cord-271972-qhr6iir6	85	43	.	.	.
cord-271972-qhr6iir6	86	1	It	-PRON-	PRP
cord-271972-qhr6iir6	86	2	has	have	VBZ
cord-271972-qhr6iir6	86	3	been	be	VBN
cord-271972-qhr6iir6	86	4	suggested	suggest	VBN
cord-271972-qhr6iir6	86	5	that	that	IN
cord-271972-qhr6iir6	86	6	the	the	DT
cord-271972-qhr6iir6	86	7	Lsm	Lsm	NNP
cord-271972-qhr6iir6	86	8	proteins	protein	NNS
cord-271972-qhr6iir6	86	9	may	may	MD
cord-271972-qhr6iir6	86	10	direct	direct	VB
cord-271972-qhr6iir6	86	11	BMV	BMV	NNP
cord-271972-qhr6iir6	86	12	RNAs	rna	NNS
cord-271972-qhr6iir6	86	13	to	to	IN
cord-271972-qhr6iir6	86	14	replication	replication	NN
cord-271972-qhr6iir6	86	15	complexes	complex	NNS
cord-271972-qhr6iir6	86	16	by	by	IN
cord-271972-qhr6iir6	86	17	recruiting	recruit	VBG
cord-271972-qhr6iir6	86	18	them	-PRON-	PRP
cord-271972-qhr6iir6	86	19	to	to	IN
cord-271972-qhr6iir6	86	20	P	p	NN
cord-271972-qhr6iir6	86	21	bodies	body	NNS
cord-271972-qhr6iir6	86	22	,	,	,
cord-271972-qhr6iir6	86	23	which	which	WDT
cord-271972-qhr6iir6	86	24	are	be	VBP
cord-271972-qhr6iir6	86	25	sites	site	NNS
cord-271972-qhr6iir6	86	26	of	of	IN
cord-271972-qhr6iir6	86	27	RNA	RNA	NNP
cord-271972-qhr6iir6	86	28	storage	storage	NN
cord-271972-qhr6iir6	86	29	and/or	and/or	CC
cord-271972-qhr6iir6	86	30	decay	decay	VB
cord-271972-qhr6iir6	86	31	19	19	CD
cord-271972-qhr6iir6	87	1	(	(	-LRB-
cord-271972-qhr6iir6	87	2	Figure	figure	NN
cord-271972-qhr6iir6	87	3	2	2	CD
cord-271972-qhr6iir6	87	4	(	(	-LRB-
cord-271972-qhr6iir6	87	5	b	b	NN
cord-271972-qhr6iir6	87	6	)	)	-RRB-
cord-271972-qhr6iir6	87	7	)	)	-RRB-
cord-271972-qhr6iir6	87	8	.	.	.
cord-271972-qhr6iir6	88	1	Because	because	IN
cord-271972-qhr6iir6	88	2	P	p	NN
cord-271972-qhr6iir6	88	3	bodies	body	NNS
cord-271972-qhr6iir6	88	4	are	be	VBP
cord-271972-qhr6iir6	88	5	thought	think	VBN
cord-271972-qhr6iir6	88	6	to	to	TO
cord-271972-qhr6iir6	88	7	hold	hold	VB
cord-271972-qhr6iir6	88	8	mRNAs	mrna	NNS
cord-271972-qhr6iir6	88	9	in	in	IN
cord-271972-qhr6iir6	88	10	a	a	DT
cord-271972-qhr6iir6	88	11	translationally	translationally	RB
cord-271972-qhr6iir6	88	12	repressed	repress	VBN
cord-271972-qhr6iir6	88	13	state	state	NN
cord-271972-qhr6iir6	88	14	,	,	,
cord-271972-qhr6iir6	88	15	20	20	CD
cord-271972-qhr6iir6	88	16	,	,	,
cord-271972-qhr6iir6	88	17	21	21	CD
cord-271972-qhr6iir6	88	18	in	in	IN
cord-271972-qhr6iir6	88	19	principle	principle	NN
cord-271972-qhr6iir6	88	20	they	-PRON-	PRP
cord-271972-qhr6iir6	88	21	could	could	MD
cord-271972-qhr6iir6	88	22	be	be	VB
cord-271972-qhr6iir6	88	23	ideal	ideal	JJ
cord-271972-qhr6iir6	88	24	sites	site	NNS
cord-271972-qhr6iir6	88	25	for	for	IN
cord-271972-qhr6iir6	88	26	viral	viral	JJ
cord-271972-qhr6iir6	88	27	genome	genome	NN
cord-271972-qhr6iir6	88	28	replication	replication	NN
cord-271972-qhr6iir6	88	29	.	.	.
cord-271972-qhr6iir6	89	1	19	19	CD
cord-271972-qhr6iir6	90	1	Surprisingly	surprisingly	RB
cord-271972-qhr6iir6	90	2	,	,	,
cord-271972-qhr6iir6	90	3	when	when	WRB
cord-271972-qhr6iir6	90	4	the	the	DT
cord-271972-qhr6iir6	90	5	BMV	BMV	NNP
cord-271972-qhr6iir6	90	6	and	and	CC
cord-271972-qhr6iir6	90	7	HCV	HCV	NNP
cord-271972-qhr6iir6	90	8	3	3	CD
cord-271972-qhr6iir6	90	9	tRNA	tRNA	NNP
cord-271972-qhr6iir6	90	10	-	-	HYPH
cord-271972-qhr6iir6	90	11	like	like	JJ
cord-271972-qhr6iir6	90	12	structure	structure	NN
cord-271972-qhr6iir6	90	13	are	be	VBP
cord-271972-qhr6iir6	90	14	replaced	replace	VBN
cord-271972-qhr6iir6	90	15	with	with	IN
cord-271972-qhr6iir6	90	16	a	a	DT
cord-271972-qhr6iir6	90	17	poly(A	poly(a	JJ
cord-271972-qhr6iir6	90	18	)	)	-RRB-
cord-271972-qhr6iir6	90	19	tail	tail	NN
cord-271972-qhr6iir6	90	20	,	,	,
cord-271972-qhr6iir6	90	21	the	the	DT
cord-271972-qhr6iir6	90	22	Lsm	Lsm	NNP
cord-271972-qhr6iir6	90	23	complex	complex	NN
cord-271972-qhr6iir6	90	24	is	be	VBZ
cord-271972-qhr6iir6	90	25	no	no	DT
cord-271972-qhr6iir6	90	26	longer	long	RBR
cord-271972-qhr6iir6	90	27	required	require	VBN
cord-271972-qhr6iir6	90	28	for	for	IN
cord-271972-qhr6iir6	90	29	viral	viral	JJ
cord-271972-qhr6iir6	90	30	RNA	RNA	NNP
cord-271972-qhr6iir6	90	31	accumulation	accumulation	NN
cord-271972-qhr6iir6	90	32	and	and	CC
cord-271972-qhr6iir6	90	33	translation	translation	NN
cord-271972-qhr6iir6	90	34	.	.	.
cord-271972-qhr6iir6	91	1	[	[	-LRB-
cord-271972-qhr6iir6	91	2	16	16	CD
cord-271972-qhr6iir6	91	3	]	]	-RRB-
cord-271972-qhr6iir6	91	4	[	[	-LRB-
cord-271972-qhr6iir6	91	5	17	17	CD
cord-271972-qhr6iir6	91	6	]	]	-RRB-
cord-271972-qhr6iir6	91	7	[	[	-LRB-
cord-271972-qhr6iir6	91	8	18	18	CD
cord-271972-qhr6iir6	91	9	]	]	-RRB-
cord-271972-qhr6iir6	92	1	One	one	CD
cord-271972-qhr6iir6	92	2	hypothesis	hypothesis	NN
cord-271972-qhr6iir6	92	3	is	be	VBZ
cord-271972-qhr6iir6	92	4	that	that	IN
cord-271972-qhr6iir6	92	5	these	these	DT
cord-271972-qhr6iir6	92	6	viruses	virus	NNS
cord-271972-qhr6iir6	92	7	co	co	VBP
cord-271972-qhr6iir6	92	8	-	-	VB
cord-271972-qhr6iir6	92	9	opt	opt	VB
cord-271972-qhr6iir6	92	10	Lsm	Lsm	NNP
cord-271972-qhr6iir6	92	11	to	to	TO
cord-271972-qhr6iir6	92	12	compensate	compensate	VB
cord-271972-qhr6iir6	92	13	for	for	IN
cord-271972-qhr6iir6	92	14	the	the	DT
cord-271972-qhr6iir6	92	15	RNA	RNA	NNP
cord-271972-qhr6iir6	92	16	stabilizing	stabilizing	NN
cord-271972-qhr6iir6	92	17	functions	function	NNS
cord-271972-qhr6iir6	92	18	normally	normally	RB
cord-271972-qhr6iir6	92	19	provided	provide	VBN
cord-271972-qhr6iir6	92	20	by	by	IN
cord-271972-qhr6iir6	92	21	polyadenylation	polyadenylation	NN
cord-271972-qhr6iir6	92	22	and	and	CC
cord-271972-qhr6iir6	92	23	its	-PRON-	PRP$
cord-271972-qhr6iir6	92	24	associated	associate	VBN
cord-271972-qhr6iir6	92	25	poly(A	poly(A	NNP
cord-271972-qhr6iir6	92	26	)	)	-RRB-
cord-271972-qhr6iir6	93	1	binding	bind	VBG
cord-271972-qhr6iir6	93	2	protein	protein	NN
cord-271972-qhr6iir6	93	3	(	(	-LRB-
cord-271972-qhr6iir6	93	4	PABP	PABP	NNP
cord-271972-qhr6iir6	93	5	)	)	-RRB-
cord-271972-qhr6iir6	93	6	.	.	.
cord-271972-qhr6iir6	94	1	However	however	RB
cord-271972-qhr6iir6	94	2	,	,	,
cord-271972-qhr6iir6	94	3	association	association	NN
cord-271972-qhr6iir6	94	4	with	with	IN
cord-271972-qhr6iir6	94	5	PABP	PABP	NNP
cord-271972-qhr6iir6	94	6	should	should	MD
cord-271972-qhr6iir6	94	7	not	not	RB
cord-271972-qhr6iir6	94	8	result	result	VB
cord-271972-qhr6iir6	94	9	in	in	IN
cord-271972-qhr6iir6	94	10	RNA	rna	NN
cord-271972-qhr6iir6	94	11	recruitment	recruitment	NN
cord-271972-qhr6iir6	94	12	to	to	IN
cord-271972-qhr6iir6	94	13	P	p	NN
cord-271972-qhr6iir6	94	14	bodies	body	NNS
cord-271972-qhr6iir6	94	15	,	,	,
cord-271972-qhr6iir6	94	16	as	as	IN
cord-271972-qhr6iir6	94	17	PABP	PABP	NNP
cord-271972-qhr6iir6	94	18	is	be	VBZ
cord-271972-qhr6iir6	94	19	not	not	RB
cord-271972-qhr6iir6	94	20	a	a	DT
cord-271972-qhr6iir6	94	21	component	component	NN
cord-271972-qhr6iir6	94	22	of	of	IN
cord-271972-qhr6iir6	94	23	P	p	NN
cord-271972-qhr6iir6	94	24	bodies	body	NNS
cord-271972-qhr6iir6	94	25	.	.	.
cord-271972-qhr6iir6	95	1	22	22	CD
cord-271972-qhr6iir6	96	1	In	in	IN
cord-271972-qhr6iir6	96	2	addition	addition	NN
cord-271972-qhr6iir6	96	3	,	,	,
cord-271972-qhr6iir6	96	4	the	the	DT
cord-271972-qhr6iir6	96	5	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	96	6	associated	associate	VBN
cord-271972-qhr6iir6	96	7	with	with	IN
cord-271972-qhr6iir6	96	8	P	p	NN
cord-271972-qhr6iir6	96	9	bodies	body	NNS
cord-271972-qhr6iir6	96	10	are	be	VBP
cord-271972-qhr6iir6	96	11	generally	generally	RB
cord-271972-qhr6iir6	96	12	believed	believe	VBN
cord-271972-qhr6iir6	96	13	to	to	TO
cord-271972-qhr6iir6	96	14	be	be	VB
cord-271972-qhr6iir6	96	15	deadenylated	deadenylate	VBN
cord-271972-qhr6iir6	96	16	.	.	.
cord-271972-qhr6iir6	97	1	23	23	CD
cord-271972-qhr6iir6	98	1	Therefore	therefore	RB
cord-271972-qhr6iir6	98	2	,	,	,
cord-271972-qhr6iir6	98	3	it	-PRON-	PRP
cord-271972-qhr6iir6	98	4	is	be	VBZ
cord-271972-qhr6iir6	98	5	not	not	RB
cord-271972-qhr6iir6	98	6	clear	clear	JJ
cord-271972-qhr6iir6	98	7	that	that	IN
cord-271972-qhr6iir6	98	8	PABP	PABP	NNP
cord-271972-qhr6iir6	98	9	and	and	CC
cord-271972-qhr6iir6	98	10	Lsm	Lsm	NNP
cord-271972-qhr6iir6	98	11	association	association	NN
cord-271972-qhr6iir6	98	12	could	could	MD
cord-271972-qhr6iir6	98	13	substitute	substitute	VB
cord-271972-qhr6iir6	98	14	for	for	IN
cord-271972-qhr6iir6	98	15	each	each	DT
cord-271972-qhr6iir6	98	16	other	other	JJ
cord-271972-qhr6iir6	98	17	in	in	IN
cord-271972-qhr6iir6	98	18	this	this	DT
cord-271972-qhr6iir6	98	19	system	system	NN
cord-271972-qhr6iir6	98	20	.	.	.
cord-271972-qhr6iir6	99	1	Further	further	JJ
cord-271972-qhr6iir6	99	2	studies	study	NNS
cord-271972-qhr6iir6	99	3	are	be	VBP
cord-271972-qhr6iir6	99	4	therefore	therefore	RB
cord-271972-qhr6iir6	99	5	needed	need	VBN
cord-271972-qhr6iir6	99	6	to	to	TO
cord-271972-qhr6iir6	99	7	delineate	delineate	VB
cord-271972-qhr6iir6	99	8	how	how	WRB
cord-271972-qhr6iir6	99	9	and	and	CC
cord-271972-qhr6iir6	99	10	why	why	WRB
cord-271972-qhr6iir6	99	11	the	the	DT
cord-271972-qhr6iir6	99	12	Lsm	Lsm	NNP
cord-271972-qhr6iir6	99	13	complex	complex	NN
cord-271972-qhr6iir6	99	14	is	be	VBZ
cord-271972-qhr6iir6	99	15	required	require	VBN
cord-271972-qhr6iir6	99	16	for	for	IN
cord-271972-qhr6iir6	99	17	viral	viral	JJ
cord-271972-qhr6iir6	99	18	RNA	RNA	NNP
cord-271972-qhr6iir6	99	19	replication	replication	NN
cord-271972-qhr6iir6	99	20	only	only	RB
cord-271972-qhr6iir6	99	21	in	in	IN
cord-271972-qhr6iir6	99	22	the	the	DT
cord-271972-qhr6iir6	99	23	absence	absence	NN
cord-271972-qhr6iir6	99	24	of	of	IN
cord-271972-qhr6iir6	99	25	polyadenylation	polyadenylation	NN
cord-271972-qhr6iir6	99	26	.	.	.
cord-271972-qhr6iir6	100	1	Cellular	cellular	JJ
cord-271972-qhr6iir6	100	2	Lsm	Lsm	NNP
cord-271972-qhr6iir6	100	3	proteins	protein	NNS
cord-271972-qhr6iir6	100	4	may	may	MD
cord-271972-qhr6iir6	100	5	also	also	RB
cord-271972-qhr6iir6	100	6	play	play	VB
cord-271972-qhr6iir6	100	7	a	a	DT
cord-271972-qhr6iir6	100	8	role	role	NN
cord-271972-qhr6iir6	100	9	in	in	IN
cord-271972-qhr6iir6	100	10	the	the	DT
cord-271972-qhr6iir6	100	11	stability	stability	NN
cord-271972-qhr6iir6	100	12	of	of	IN
cord-271972-qhr6iir6	100	13	mRNAs	mrnas	CD
cord-271972-qhr6iir6	100	14	of	of	IN
cord-271972-qhr6iir6	100	15	poxviruses	poxvirus	NNS
cord-271972-qhr6iir6	100	16	,	,	,
cord-271972-qhr6iir6	100	17	which	which	WDT
cord-271972-qhr6iir6	100	18	are	be	VBP
cord-271972-qhr6iir6	100	19	large	large	JJ
cord-271972-qhr6iir6	100	20	DNA	dna	NN
cord-271972-qhr6iir6	100	21	viruses	virus	NNS
cord-271972-qhr6iir6	100	22	that	that	WDT
cord-271972-qhr6iir6	100	23	replicate	replicate	VBP
cord-271972-qhr6iir6	100	24	in	in	IN
cord-271972-qhr6iir6	100	25	the	the	DT
cord-271972-qhr6iir6	100	26	cytoplasm	cytoplasm	NN
cord-271972-qhr6iir6	101	1	(	(	-LRB-
cord-271972-qhr6iir6	101	2	Figure	figure	NN
cord-271972-qhr6iir6	101	3	2	2	CD
cord-271972-qhr6iir6	101	4	(	(	-LRB-
cord-271972-qhr6iir6	101	5	b	b	NN
cord-271972-qhr6iir6	101	6	)	)	-RRB-
cord-271972-qhr6iir6	101	7	)	)	-RRB-
cord-271972-qhr6iir6	101	8	.	.	.
cord-271972-qhr6iir6	102	1	Transcripts	transcript	NNS
cord-271972-qhr6iir6	102	2	from	from	IN
cord-271972-qhr6iir6	102	3	orthopoxviridae	orthopoxviridae	NN
cord-271972-qhr6iir6	102	4	,	,	,
cord-271972-qhr6iir6	102	5	particularly	particularly	RB
cord-271972-qhr6iir6	102	6	those	those	DT
cord-271972-qhr6iir6	102	7	expressed	express	VBN
cord-271972-qhr6iir6	102	8	later	later	RB
cord-271972-qhr6iir6	102	9	in	in	IN
cord-271972-qhr6iir6	102	10	infection	infection	NN
cord-271972-qhr6iir6	102	11	,	,	,
cord-271972-qhr6iir6	102	12	often	often	RB
cord-271972-qhr6iir6	102	13	contain	contain	VBP
cord-271972-qhr6iir6	102	14	non	non	JJ
cord-271972-qhr6iir6	102	15	-	-	JJ
cord-271972-qhr6iir6	102	16	templated	templated	JJ
cord-271972-qhr6iir6	102	17	adenosine	adenosine	NN
cord-271972-qhr6iir6	102	18	stretches	stretch	NNS
cord-271972-qhr6iir6	102	19	of	of	IN
cord-271972-qhr6iir6	102	20	5	5	CD
cord-271972-qhr6iir6	102	21	-	-	SYM
cord-271972-qhr6iir6	102	22	40	40	CD
cord-271972-qhr6iir6	102	23	nucleotides	nucleotide	NNS
cord-271972-qhr6iir6	102	24	within	within	IN
cord-271972-qhr6iir6	102	25	their	-PRON-	PRP$
cord-271972-qhr6iir6	102	26	5	5	CD
cord-271972-qhr6iir6	102	27	UTRs	utr	NNS
cord-271972-qhr6iir6	102	28	,	,	,
cord-271972-qhr6iir6	102	29	thought	think	VBN
cord-271972-qhr6iir6	102	30	to	to	TO
cord-271972-qhr6iir6	102	31	be	be	VB
cord-271972-qhr6iir6	102	32	generated	generate	VBN
cord-271972-qhr6iir6	102	33	by	by	IN
cord-271972-qhr6iir6	102	34	polymerase	polymerase	NN
cord-271972-qhr6iir6	102	35	stuttering	stuttering	NN
cord-271972-qhr6iir6	102	36	.	.	.
cord-271972-qhr6iir6	103	1	24	24	CD
cord-271972-qhr6iir6	103	2	5	5	CD
cord-271972-qhr6iir6	103	3	adenosine	adenosine	NN
cord-271972-qhr6iir6	103	4	tracts	tract	NNS
cord-271972-qhr6iir6	103	5	of	of	IN
cord-271972-qhr6iir6	103	6	at	at	RB
cord-271972-qhr6iir6	103	7	least	least	JJS
cord-271972-qhr6iir6	103	8	10	10	CD
cord-271972-qhr6iir6	103	9	nt	nt	RB
cord-271972-qhr6iir6	103	10	were	be	VBD
cord-271972-qhr6iir6	103	11	shown	show	VBN
cord-271972-qhr6iir6	103	12	to	to	TO
cord-271972-qhr6iir6	103	13	promote	promote	VB
cord-271972-qhr6iir6	103	14	mRNA	mRNA	NNP
cord-271972-qhr6iir6	103	15	stabilization	stabilization	NN
cord-271972-qhr6iir6	103	16	in	in	IN
cord-271972-qhr6iir6	103	17	cells	cell	NNS
cord-271972-qhr6iir6	103	18	and	and	CC
cord-271972-qhr6iir6	103	19	in	in	IN
cord-271972-qhr6iir6	103	20	cytoplasmic	cytoplasmic	JJ
cord-271972-qhr6iir6	103	21	extracts	extract	NNS
cord-271972-qhr6iir6	103	22	by	by	IN
cord-271972-qhr6iir6	103	23	inhibiting	inhibit	VBG
cord-271972-qhr6iir6	103	24	both	both	CC
cord-271972-qhr6iir6	103	25	decapping	decapping	NN
cord-271972-qhr6iir6	103	26	and	and	CC
cord-271972-qhr6iir6	103	27	3	3	CD
cord-271972-qhr6iir6	103	28	→5	→5	JJ
cord-271972-qhr6iir6	103	29	exonucleolytic	exonucleolytic	JJ
cord-271972-qhr6iir6	103	30	decay	decay	NN
cord-271972-qhr6iir6	103	31	of	of	IN
cord-271972-qhr6iir6	103	32	the	the	DT
cord-271972-qhr6iir6	103	33	RNA	RNA	NNP
cord-271972-qhr6iir6	103	34	.	.	.
cord-271972-qhr6iir6	104	1	25	25	CD
cord-271972-qhr6iir6	105	1	Although	although	IN
cord-271972-qhr6iir6	105	2	these	these	DT
cord-271972-qhr6iir6	105	3	adenosine	adenosine	NN
cord-271972-qhr6iir6	105	4	stretches	stretch	NNS
cord-271972-qhr6iir6	105	5	bind	bind	VBP
cord-271972-qhr6iir6	105	6	PABP	PABP	NNP
cord-271972-qhr6iir6	105	7	,	,	,
cord-271972-qhr6iir6	105	8	titrating	titrate	VBG
cord-271972-qhr6iir6	105	9	away	away	RP
cord-271972-qhr6iir6	105	10	PABP	PABP	NNP
cord-271972-qhr6iir6	105	11	with	with	IN
cord-271972-qhr6iir6	105	12	excess	excess	JJ
cord-271972-qhr6iir6	105	13	poly(A	poly(a	NN
cord-271972-qhr6iir6	105	14	)	)	-RRB-
cord-271972-qhr6iir6	106	1	RNA	RNA	NNP
cord-271972-qhr6iir6	106	2	does	do	VBZ
cord-271972-qhr6iir6	106	3	not	not	RB
cord-271972-qhr6iir6	106	4	affect	affect	VB
cord-271972-qhr6iir6	106	5	the	the	DT
cord-271972-qhr6iir6	106	6	stability	stability	NN
cord-271972-qhr6iir6	106	7	of	of	IN
cord-271972-qhr6iir6	106	8	the	the	DT
cord-271972-qhr6iir6	106	9	5	5	CD
cord-271972-qhr6iir6	106	10	adenosine	adenosine	NN
cord-271972-qhr6iir6	106	11	tractcontaining	tractcontaine	VBG
cord-271972-qhr6iir6	106	12	transcripts	transcript	NNS
cord-271972-qhr6iir6	106	13	.	.	.
cord-271972-qhr6iir6	107	1	Their	-PRON-	PRP$
cord-271972-qhr6iir6	107	2	stabilization	stabilization	NN
cord-271972-qhr6iir6	107	3	instead	instead	RB
cord-271972-qhr6iir6	107	4	correlates	correlate	VBZ
cord-271972-qhr6iir6	107	5	with	with	IN
cord-271972-qhr6iir6	107	6	direct	direct	JJ
cord-271972-qhr6iir6	107	7	binding	binding	NN
cord-271972-qhr6iir6	107	8	of	of	IN
cord-271972-qhr6iir6	107	9	the	the	DT
cord-271972-qhr6iir6	107	10	Lsm1	Lsm1	NNP
cord-271972-qhr6iir6	107	11	-	-	HYPH
cord-271972-qhr6iir6	107	12	7	7	CD
cord-271972-qhr6iir6	107	13	complex	complex	NN
cord-271972-qhr6iir6	107	14	.	.	.
cord-271972-qhr6iir6	108	1	25	25	CD
cord-271972-qhr6iir6	108	2	Poxviruses	Poxviruses	NNPS
cord-271972-qhr6iir6	108	3	encode	encode	VBP
cord-271972-qhr6iir6	108	4	two	two	CD
cord-271972-qhr6iir6	108	5	decapping	decapping	NN
cord-271972-qhr6iir6	108	6	proteins	protein	NNS
cord-271972-qhr6iir6	108	7	,	,	,
cord-271972-qhr6iir6	108	8	D9	D9	NNP
cord-271972-qhr6iir6	108	9	and	and	CC
cord-271972-qhr6iir6	108	10	D10	D10	NNP
cord-271972-qhr6iir6	108	11	,	,	,
cord-271972-qhr6iir6	108	12	which	which	WDT
cord-271972-qhr6iir6	108	13	contribute	contribute	VBP
cord-271972-qhr6iir6	108	14	to	to	IN
cord-271972-qhr6iir6	108	15	the	the	DT
cord-271972-qhr6iir6	108	16	global	global	JJ
cord-271972-qhr6iir6	108	17	cellular	cellular	JJ
cord-271972-qhr6iir6	108	18	mRNA	mRNA	NNP
cord-271972-qhr6iir6	108	19	turnover	turnover	NN
cord-271972-qhr6iir6	108	20	that	that	WDT
cord-271972-qhr6iir6	108	21	occurs	occur	VBZ
cord-271972-qhr6iir6	108	22	during	during	IN
cord-271972-qhr6iir6	108	23	poxvirus	poxvirus	NNP
cord-271972-qhr6iir6	108	24	infection	infection	NN
cord-271972-qhr6iir6	108	25	.	.	.
cord-271972-qhr6iir6	109	1	However	however	RB
cord-271972-qhr6iir6	109	2	,	,	,
cord-271972-qhr6iir6	109	3	D9	D9	NNP
cord-271972-qhr6iir6	109	4	/	/	SYM
cord-271972-qhr6iir6	109	5	D10	D10	NNP
cord-271972-qhr6iir6	109	6	can	can	MD
cord-271972-qhr6iir6	109	7	also	also	RB
cord-271972-qhr6iir6	109	8	target	target	VB
cord-271972-qhr6iir6	109	9	viral	viral	JJ
cord-271972-qhr6iir6	109	10	transcripts	transcript	NNS
cord-271972-qhr6iir6	109	11	and	and	CC
cord-271972-qhr6iir6	109	12	may	may	MD
cord-271972-qhr6iir6	109	13	restrict	restrict	VB
cord-271972-qhr6iir6	109	14	expression	expression	NN
cord-271972-qhr6iir6	109	15	of	of	IN
cord-271972-qhr6iir6	109	16	early	early	JJ
cord-271972-qhr6iir6	109	17	viral	viral	JJ
cord-271972-qhr6iir6	109	18	genes	gene	NNS
cord-271972-qhr6iir6	109	19	.	.	.
cord-271972-qhr6iir6	110	1	[	[	-LRB-
cord-271972-qhr6iir6	110	2	26	26	CD
cord-271972-qhr6iir6	110	3	]	]	-RRB-
cord-271972-qhr6iir6	110	4	[	[	-LRB-
cord-271972-qhr6iir6	110	5	27	27	CD
cord-271972-qhr6iir6	110	6	]	]	-RRB-
cord-271972-qhr6iir6	110	7	[	[	-LRB-
cord-271972-qhr6iir6	110	8	28	28	CD
cord-271972-qhr6iir6	110	9	]	]	-RRB-
cord-271972-qhr6iir6	111	1	Thus	thus	RB
cord-271972-qhr6iir6	111	2	,	,	,
cord-271972-qhr6iir6	111	3	Lsm	Lsm	NNP
cord-271972-qhr6iir6	111	4	proteins	protein	NNS
cord-271972-qhr6iir6	111	5	may	may	MD
cord-271972-qhr6iir6	111	6	participate	participate	VB
cord-271972-qhr6iir6	111	7	in	in	IN
cord-271972-qhr6iir6	111	8	the	the	DT
cord-271972-qhr6iir6	111	9	protection	protection	NN
cord-271972-qhr6iir6	111	10	of	of	IN
cord-271972-qhr6iir6	111	11	late	late	JJ
cord-271972-qhr6iir6	111	12	viral	viral	JJ
cord-271972-qhr6iir6	111	13	messages	message	NNS
cord-271972-qhr6iir6	111	14	from	from	IN
cord-271972-qhr6iir6	111	15	the	the	DT
cord-271972-qhr6iir6	111	16	viral	viral	JJ
cord-271972-qhr6iir6	111	17	decapping	decapping	NN
cord-271972-qhr6iir6	111	18	proteins	protein	NNS
cord-271972-qhr6iir6	111	19	,	,	,
cord-271972-qhr6iir6	111	20	although	although	IN
cord-271972-qhr6iir6	111	21	it	-PRON-	PRP
cord-271972-qhr6iir6	111	22	has	have	VBZ
cord-271972-qhr6iir6	111	23	yet	yet	RB
cord-271972-qhr6iir6	111	24	to	to	TO
cord-271972-qhr6iir6	111	25	be	be	VB
cord-271972-qhr6iir6	111	26	directly	directly	RB
cord-271972-qhr6iir6	111	27	proven	prove	VBN
cord-271972-qhr6iir6	111	28	that	that	IN
cord-271972-qhr6iir6	111	29	this	this	DT
cord-271972-qhr6iir6	111	30	complex	complex	NN
cord-271972-qhr6iir6	111	31	protects	protect	VBZ
cord-271972-qhr6iir6	111	32	viral	viral	JJ
cord-271972-qhr6iir6	111	33	messages	message	NNS
cord-271972-qhr6iir6	111	34	during	during	IN
cord-271972-qhr6iir6	111	35	infection	infection	NN
cord-271972-qhr6iir6	111	36	or	or	CC
cord-271972-qhr6iir6	111	37	that	that	IN
cord-271972-qhr6iir6	111	38	it	-PRON-	PRP
cord-271972-qhr6iir6	111	39	blocks	block	VBZ
cord-271972-qhr6iir6	111	40	D9	D9	NNP
cord-271972-qhr6iir6	111	41	/	/	SYM
cord-271972-qhr6iir6	111	42	D10	D10	NNP
cord-271972-qhr6iir6	111	43	decapping	decapping	NN
cord-271972-qhr6iir6	111	44	activity	activity	NN
cord-271972-qhr6iir6	111	45	.	.	.
cord-271972-qhr6iir6	112	1	25	25	CD
cord-271972-qhr6iir6	113	1	It	-PRON-	PRP
cord-271972-qhr6iir6	113	2	is	be	VBZ
cord-271972-qhr6iir6	113	3	notable	notable	JJ
cord-271972-qhr6iir6	113	4	that	that	IN
cord-271972-qhr6iir6	113	5	the	the	DT
cord-271972-qhr6iir6	113	6	virus	virus	NN
cord-271972-qhr6iir6	113	7	-	-	HYPH
cord-271972-qhr6iir6	113	8	associated	associate	VBN
cord-271972-qhr6iir6	113	9	roles	role	NNS
cord-271972-qhr6iir6	113	10	of	of	IN
cord-271972-qhr6iir6	113	11	the	the	DT
cord-271972-qhr6iir6	113	12	Lsm	Lsm	NNP
cord-271972-qhr6iir6	113	13	complex	complex	NN
cord-271972-qhr6iir6	113	14	in	in	IN
cord-271972-qhr6iir6	113	15	mRNA	mRNA	NNP
cord-271972-qhr6iir6	113	16	stabilization	stabilization	NN
cord-271972-qhr6iir6	113	17	,	,	,
cord-271972-qhr6iir6	113	18	enhanced	enhanced	JJ
cord-271972-qhr6iir6	113	19	translation	translation	NN
cord-271972-qhr6iir6	113	20	,	,	,
cord-271972-qhr6iir6	113	21	and	and	CC
cord-271972-qhr6iir6	113	22	replication	replication	NN
cord-271972-qhr6iir6	113	23	are	be	VBP
cord-271972-qhr6iir6	113	24	at	at	IN
cord-271972-qhr6iir6	113	25	odds	odd	NNS
cord-271972-qhr6iir6	113	26	with	with	IN
cord-271972-qhr6iir6	113	27	its	-PRON-	PRP$
cord-271972-qhr6iir6	113	28	established	establish	VBN
cord-271972-qhr6iir6	113	29	cellular	cellular	JJ
cord-271972-qhr6iir6	113	30	function	function	NN
cord-271972-qhr6iir6	113	31	in	in	IN
cord-271972-qhr6iir6	113	32	activating	activate	VBG
cord-271972-qhr6iir6	113	33	mRNA	mRNA	NNP
cord-271972-qhr6iir6	113	34	decapping	decappe	VBG
cord-271972-qhr6iir6	113	35	to	to	TO
cord-271972-qhr6iir6	113	36	facilitate	facilitate	VB
cord-271972-qhr6iir6	113	37	message	message	NN
cord-271972-qhr6iir6	113	38	degradation	degradation	NN
cord-271972-qhr6iir6	113	39	.	.	.
cord-271972-qhr6iir6	114	1	While	while	IN
cord-271972-qhr6iir6	114	2	it	-PRON-	PRP
cord-271972-qhr6iir6	114	3	is	be	VBZ
cord-271972-qhr6iir6	114	4	formally	formally	RB
cord-271972-qhr6iir6	114	5	possible	possible	JJ
cord-271972-qhr6iir6	114	6	that	that	IN
cord-271972-qhr6iir6	114	7	these	these	DT
cord-271972-qhr6iir6	114	8	viruses	virus	NNS
cord-271972-qhr6iir6	114	9	are	be	VBP
cord-271972-qhr6iir6	114	10	manipulating	manipulate	VBG
cord-271972-qhr6iir6	114	11	the	the	DT
cord-271972-qhr6iir6	114	12	Lsm	Lsm	NNP
cord-271972-qhr6iir6	114	13	complex	complex	NN
cord-271972-qhr6iir6	114	14	to	to	TO
cord-271972-qhr6iir6	114	15	induce	induce	VB
cord-271972-qhr6iir6	114	16	novel	novel	JJ
cord-271972-qhr6iir6	114	17	activities	activity	NNS
cord-271972-qhr6iir6	114	18	,	,	,
cord-271972-qhr6iir6	114	19	a	a	DT
cord-271972-qhr6iir6	114	20	more	more	RBR
cord-271972-qhr6iir6	114	21	likely	likely	JJ
cord-271972-qhr6iir6	114	22	explanation	explanation	NN
cord-271972-qhr6iir6	114	23	is	be	VBZ
cord-271972-qhr6iir6	114	24	that	that	IN
cord-271972-qhr6iir6	114	25	the	the	DT
cord-271972-qhr6iir6	114	26	Lsm	Lsm	NNP
cord-271972-qhr6iir6	114	27	proteins	protein	NNS
cord-271972-qhr6iir6	114	28	have	have	VBP
cord-271972-qhr6iir6	114	29	multifaceted	multifacete	VBN
cord-271972-qhr6iir6	114	30	roles	role	NNS
cord-271972-qhr6iir6	114	31	in	in	IN
cord-271972-qhr6iir6	114	32	cellular	cellular	JJ
cord-271972-qhr6iir6	114	33	gene	gene	NN
cord-271972-qhr6iir6	114	34	expression	expression	NN
cord-271972-qhr6iir6	114	35	,	,	,
cord-271972-qhr6iir6	114	36	which	which	WDT
cord-271972-qhr6iir6	114	37	are	be	VBP
cord-271972-qhr6iir6	114	38	being	be	VBG
cord-271972-qhr6iir6	114	39	revealed	reveal	VBN
cord-271972-qhr6iir6	114	40	and	and	CC
cord-271972-qhr6iir6	114	41	exploited	exploit	VBN
cord-271972-qhr6iir6	114	42	by	by	IN
cord-271972-qhr6iir6	114	43	viruses	virus	NNS
cord-271972-qhr6iir6	114	44	.	.	.
cord-271972-qhr6iir6	115	1	Decapping	decapping	NN
cord-271972-qhr6iir6	115	2	exposes	expose	VBZ
cord-271972-qhr6iir6	115	3	the	the	DT
cord-271972-qhr6iir6	115	4	mRNA	mrna	NN
cord-271972-qhr6iir6	115	5	5	5	CD
cord-271972-qhr6iir6	115	6	end	end	NN
cord-271972-qhr6iir6	115	7	,	,	,
cord-271972-qhr6iir6	115	8	triggering	trigger	VBG
cord-271972-qhr6iir6	115	9	rapid	rapid	JJ
cord-271972-qhr6iir6	115	10	exonucleolytic	exonucleolytic	JJ
cord-271972-qhr6iir6	115	11	destruction	destruction	NN
cord-271972-qhr6iir6	115	12	of	of	IN
cord-271972-qhr6iir6	115	13	the	the	DT
cord-271972-qhr6iir6	115	14	message	message	NN
cord-271972-qhr6iir6	115	15	body	body	NN
cord-271972-qhr6iir6	115	16	predominantly	predominantly	RB
cord-271972-qhr6iir6	115	17	via	via	IN
cord-271972-qhr6iir6	115	18	the	the	DT
cord-271972-qhr6iir6	115	19	5	5	CD
cord-271972-qhr6iir6	115	20	→3	→3	NNS
cord-271972-qhr6iir6	115	21	nuclease	nuclease	FW
cord-271972-qhr6iir6	115	22	Xrn1	xrn1	NN
cord-271972-qhr6iir6	115	23	(	(	-LRB-
cord-271972-qhr6iir6	115	24	Figure	figure	NN
cord-271972-qhr6iir6	115	25	1	1	CD
cord-271972-qhr6iir6	115	26	)	)	-RRB-
cord-271972-qhr6iir6	115	27	.	.	.
cord-271972-qhr6iir6	116	1	Viruses	virus	NNS
cord-271972-qhr6iir6	116	2	lacking	lack	VBG
cord-271972-qhr6iir6	116	3	a	a	DT
cord-271972-qhr6iir6	116	4	5	5	CD
cord-271972-qhr6iir6	116	5	cap	cap	NN
cord-271972-qhr6iir6	116	6	might	may	MD
cord-271972-qhr6iir6	116	7	therefore	therefore	RB
cord-271972-qhr6iir6	116	8	be	be	VB
cord-271972-qhr6iir6	116	9	particularly	particularly	RB
cord-271972-qhr6iir6	116	10	susceptible	susceptible	JJ
cord-271972-qhr6iir6	116	11	to	to	IN
cord-271972-qhr6iir6	116	12	Xrn1-mediated	xrn1-mediated	JJ
cord-271972-qhr6iir6	116	13	degradation	degradation	NN
cord-271972-qhr6iir6	116	14	.	.	.
cord-271972-qhr6iir6	117	1	Indeed	indeed	RB
cord-271972-qhr6iir6	117	2	,	,	,
cord-271972-qhr6iir6	117	3	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	117	4	was	be	VBD
cord-271972-qhr6iir6	117	5	initially	initially	RB
cord-271972-qhr6iir6	117	6	discovered	discover	VBN
cord-271972-qhr6iir6	117	7	in	in	IN
cord-271972-qhr6iir6	117	8	the	the	DT
cord-271972-qhr6iir6	117	9	yeast	yeast	NN
cord-271972-qhr6iir6	117	10	Saccharomyces	Saccharomyces	NNP
cord-271972-qhr6iir6	117	11	cerevisiae	cerevisiae	NNS
cord-271972-qhr6iir6	117	12	for	for	IN
cord-271972-qhr6iir6	117	13	its	-PRON-	PRP$
cord-271972-qhr6iir6	117	14	'	'	``
cord-271972-qhr6iir6	117	15	Superkiller	Superkiller	NNP
cord-271972-qhr6iir6	117	16	'	'	''
cord-271972-qhr6iir6	117	17	(	(	-LRB-
cord-271972-qhr6iir6	117	18	Ski	ski	NN
cord-271972-qhr6iir6	117	19	)	)	-RRB-
cord-271972-qhr6iir6	117	20	phenotype	phenotype	NN
cord-271972-qhr6iir6	117	21	:	:	:
cord-271972-qhr6iir6	117	22	loss	loss	NN
cord-271972-qhr6iir6	117	23	of	of	IN
cord-271972-qhr6iir6	117	24	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	117	25	resulted	result	VBD
cord-271972-qhr6iir6	117	26	in	in	IN
cord-271972-qhr6iir6	117	27	cell	cell	NN
cord-271972-qhr6iir6	117	28	death	death	NN
cord-271972-qhr6iir6	117	29	as	as	IN
cord-271972-qhr6iir6	117	30	a	a	DT
cord-271972-qhr6iir6	117	31	consequence	consequence	NN
cord-271972-qhr6iir6	117	32	of	of	IN
cord-271972-qhr6iir6	117	33	increased	increase	VBN
cord-271972-qhr6iir6	117	34	levels	level	NNS
cord-271972-qhr6iir6	117	35	of	of	IN
cord-271972-qhr6iir6	117	36	the	the	DT
cord-271972-qhr6iir6	117	37	toxin	toxin	NN
cord-271972-qhr6iir6	117	38	-	-	HYPH
cord-271972-qhr6iir6	117	39	encoding	encode	VBG
cord-271972-qhr6iir6	117	40	uncapped	uncapped	JJ
cord-271972-qhr6iir6	117	41	M	M	NNP
cord-271972-qhr6iir6	117	42	satellite	satellite	NN
cord-271972-qhr6iir6	117	43	double	double	RB
cord-271972-qhr6iir6	117	44	-	-	HYPH
cord-271972-qhr6iir6	117	45	stranded	strand	VBN
cord-271972-qhr6iir6	117	46	RNA	RNA	NNP
cord-271972-qhr6iir6	117	47	(	(	-LRB-
cord-271972-qhr6iir6	117	48	dsRNA	dsrna	NN
cord-271972-qhr6iir6	117	49	)	)	-RRB-
cord-271972-qhr6iir6	117	50	of	of	IN
cord-271972-qhr6iir6	117	51	the	the	DT
cord-271972-qhr6iir6	117	52	L	L	NNP
cord-271972-qhr6iir6	117	53	-	-	HYPH
cord-271972-qhr6iir6	117	54	A	A	NNP
cord-271972-qhr6iir6	117	55	virus	virus	NN
cord-271972-qhr6iir6	117	56	.	.	.
cord-271972-qhr6iir6	118	1	29	29	CD
cord-271972-qhr6iir6	119	1	In	in	IN
cord-271972-qhr6iir6	119	2	addition	addition	NN
cord-271972-qhr6iir6	119	3	,	,	,
cord-271972-qhr6iir6	119	4	both	both	DT
cord-271972-qhr6iir6	119	5	in	in	IN
cord-271972-qhr6iir6	119	6	yeast	yeast	NN
cord-271972-qhr6iir6	119	7	30	30	CD
cord-271972-qhr6iir6	119	8	and	and	CC
cord-271972-qhr6iir6	119	9	in	in	IN
cord-271972-qhr6iir6	119	10	the	the	DT
cord-271972-qhr6iir6	119	11	plant	plant	NN
cord-271972-qhr6iir6	119	12	Nicotiana	Nicotiana	NNP
cord-271972-qhr6iir6	119	13	benthamiana	benthamiana	NNP
cord-271972-qhr6iir6	119	14	,	,	,
cord-271972-qhr6iir6	119	15	31	31	CD
cord-271972-qhr6iir6	119	16	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	119	17	and	and	CC
cord-271972-qhr6iir6	119	18	its	-PRON-	PRP$
cord-271972-qhr6iir6	119	19	homolog	homolog	NN
cord-271972-qhr6iir6	119	20	Xrn4	Xrn4	NNP
cord-271972-qhr6iir6	119	21	prevent	prevent	VBP
cord-271972-qhr6iir6	119	22	the	the	DT
cord-271972-qhr6iir6	119	23	genomic	genomic	JJ
cord-271972-qhr6iir6	119	24	RNA	RNA	NNP
cord-271972-qhr6iir6	119	25	of	of	IN
cord-271972-qhr6iir6	119	26	Tomato	Tomato	NNP
cord-271972-qhr6iir6	119	27	bushy	bushy	JJ
cord-271972-qhr6iir6	119	28	stunt	stunt	NN
cord-271972-qhr6iir6	119	29	virus	virus	NN
cord-271972-qhr6iir6	119	30	from	from	IN
cord-271972-qhr6iir6	119	31	accumulating	accumulate	VBG
cord-271972-qhr6iir6	119	32	(	(	-LRB-
cord-271972-qhr6iir6	119	33	Figure	figure	NN
cord-271972-qhr6iir6	119	34	3(a	3(a	CD
cord-271972-qhr6iir6	119	35	)	)	-RRB-
cord-271972-qhr6iir6	119	36	)	)	-RRB-
cord-271972-qhr6iir6	119	37	.	.	.
cord-271972-qhr6iir6	120	1	These	these	DT
cord-271972-qhr6iir6	120	2	exonucleases	exonuclease	NNS
cord-271972-qhr6iir6	120	3	also	also	RB
cord-271972-qhr6iir6	120	4	reduce	reduce	VBP
cord-271972-qhr6iir6	120	5	the	the	DT
cord-271972-qhr6iir6	120	6	levels	level	NNS
cord-271972-qhr6iir6	120	7	of	of	IN
cord-271972-qhr6iir6	120	8	viral	viral	JJ
cord-271972-qhr6iir6	120	9	RNA	RNA	NNP
cord-271972-qhr6iir6	120	10	intermediates	intermediate	NNS
cord-271972-qhr6iir6	120	11	necessary	necessary	JJ
cord-271972-qhr6iir6	120	12	for	for	IN
cord-271972-qhr6iir6	120	13	recombination	recombination	NN
cord-271972-qhr6iir6	120	14	,	,	,
cord-271972-qhr6iir6	120	15	a	a	DT
cord-271972-qhr6iir6	120	16	process	process	NN
cord-271972-qhr6iir6	120	17	that	that	WDT
cord-271972-qhr6iir6	120	18	some	some	DT
cord-271972-qhr6iir6	120	19	RNA	RNA	NNP
cord-271972-qhr6iir6	120	20	viruses	virus	NNS
cord-271972-qhr6iir6	120	21	exploit	exploit	VBP
cord-271972-qhr6iir6	120	22	to	to	TO
cord-271972-qhr6iir6	120	23	repair	repair	VB
cord-271972-qhr6iir6	120	24	their	-PRON-	PRP$
cord-271972-qhr6iir6	120	25	genomes	genome	NNS
cord-271972-qhr6iir6	120	26	and	and	CC
cord-271972-qhr6iir6	120	27	increase	increase	VB
cord-271972-qhr6iir6	120	28	diversity	diversity	NN
cord-271972-qhr6iir6	120	29	.	.	.
cord-271972-qhr6iir6	121	1	32	32	CD
cord-271972-qhr6iir6	122	1	How	how	WRB
cord-271972-qhr6iir6	122	2	do	do	VBP
cord-271972-qhr6iir6	122	3	RNA	RNA	NNP
cord-271972-qhr6iir6	122	4	viruses	virus	NNS
cord-271972-qhr6iir6	122	5	avoid	avoid	VB
cord-271972-qhr6iir6	122	6	Xrn1-mediated	xrn1-mediated	JJ
cord-271972-qhr6iir6	122	7	degradation	degradation	NN
cord-271972-qhr6iir6	122	8	?	?	.
cord-271972-qhr6iir6	123	1	Some	some	DT
cord-271972-qhr6iir6	123	2	protect	protect	VBP
cord-271972-qhr6iir6	123	3	their	-PRON-	PRP$
cord-271972-qhr6iir6	123	4	RNAs	rna	NNS
cord-271972-qhr6iir6	123	5	by	by	IN
cord-271972-qhr6iir6	123	6	encoding	encode	VBG
cord-271972-qhr6iir6	123	7	cis	cis	NNP
cord-271972-qhr6iir6	123	8	elements	element	NNS
cord-271972-qhr6iir6	123	9	that	that	WDT
cord-271972-qhr6iir6	123	10	can	can	MD
cord-271972-qhr6iir6	123	11	physically	physically	RB
cord-271972-qhr6iir6	123	12	block	block	VB
cord-271972-qhr6iir6	123	13	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	123	14	.	.	.
cord-271972-qhr6iir6	124	1	The	the	DT
cord-271972-qhr6iir6	124	2	yeast	yeast	NN
cord-271972-qhr6iir6	124	3	20S	20S	NNP
cord-271972-qhr6iir6	124	4	RNA	RNA	NNP
cord-271972-qhr6iir6	124	5	narnavirus	narnavirus	NNP
cord-271972-qhr6iir6	124	6	,	,	,
cord-271972-qhr6iir6	124	7	for	for	IN
cord-271972-qhr6iir6	124	8	example	example	NN
cord-271972-qhr6iir6	124	9	,	,	,
cord-271972-qhr6iir6	124	10	has	have	VBZ
cord-271972-qhr6iir6	124	11	a	a	DT
cord-271972-qhr6iir6	124	12	highly	highly	RB
cord-271972-qhr6iir6	124	13	structured	structured	JJ
cord-271972-qhr6iir6	124	14	G	g	NN
cord-271972-qhr6iir6	124	15	-	-	HYPH
cord-271972-qhr6iir6	124	16	rich	rich	JJ
cord-271972-qhr6iir6	124	17	motif	motif	NN
cord-271972-qhr6iir6	124	18	in	in	IN
cord-271972-qhr6iir6	124	19	its	-PRON-	PRP$
cord-271972-qhr6iir6	124	20	5	5	CD
cord-271972-qhr6iir6	124	21	region	region	NN
cord-271972-qhr6iir6	124	22	that	that	WDT
cord-271972-qhr6iir6	124	23	can	can	MD
cord-271972-qhr6iir6	124	24	block	block	VB
cord-271972-qhr6iir6	124	25	Xrn1	xrn1	JJ
cord-271972-qhr6iir6	124	26	activity	activity	NN
cord-271972-qhr6iir6	124	27	,	,	,
cord-271972-qhr6iir6	124	28	thereby	thereby	RB
cord-271972-qhr6iir6	124	29	likely	likely	RB
cord-271972-qhr6iir6	124	30	enhancing	enhance	VBG
cord-271972-qhr6iir6	124	31	the	the	DT
cord-271972-qhr6iir6	124	32	20S	20s	CD
cord-271972-qhr6iir6	124	33	virus	virus	NN
cord-271972-qhr6iir6	124	34	persistence	persistence	NN
cord-271972-qhr6iir6	124	35	in	in	IN
cord-271972-qhr6iir6	124	36	yeast	yeast	NN
cord-271972-qhr6iir6	124	37	laboratory	laboratory	NN
cord-271972-qhr6iir6	125	1	strains	strain	NNS
cord-271972-qhr6iir6	125	2	33	33	CD
cord-271972-qhr6iir6	126	1	(	(	-LRB-
cord-271972-qhr6iir6	126	2	Figure	figure	NN
cord-271972-qhr6iir6	126	3	3(b	3(b	CD
cord-271972-qhr6iir6	126	4	)	)	-RRB-
cord-271972-qhr6iir6	126	5	)	)	-RRB-
cord-271972-qhr6iir6	126	6	.	.	.
cord-271972-qhr6iir6	127	1	In	in	IN
cord-271972-qhr6iir6	127	2	contrast	contrast	NN
cord-271972-qhr6iir6	127	3	,	,	,
cord-271972-qhr6iir6	127	4	poliovirus	poliovirus	NN
cord-271972-qhr6iir6	127	5	(	(	-LRB-
cord-271972-qhr6iir6	127	6	PV	PV	NNP
cord-271972-qhr6iir6	127	7	)	)	-RRB-
cord-271972-qhr6iir6	127	8	recruits	recruit	VBZ
cord-271972-qhr6iir6	127	9	a	a	DT
cord-271972-qhr6iir6	127	10	ribonucleoprotein	ribonucleoprotein	NN
cord-271972-qhr6iir6	127	11	(	(	-LRB-
cord-271972-qhr6iir6	127	12	RNP	RNP	NNP
cord-271972-qhr6iir6	127	13	)	)	-RRB-
cord-271972-qhr6iir6	127	14	complex	complex	NN
cord-271972-qhr6iir6	127	15	including	include	VBG
cord-271972-qhr6iir6	127	16	poly(rC	poly(rc	CD
cord-271972-qhr6iir6	127	17	)	)	-RRB-
cord-271972-qhr6iir6	128	1	binding	bind	VBG
cord-271972-qhr6iir6	128	2	proteins	protein	NNS
cord-271972-qhr6iir6	128	3	to	to	IN
cord-271972-qhr6iir6	128	4	a	a	DT
cord-271972-qhr6iir6	128	5	5	5	CD
cord-271972-qhr6iir6	128	6	cloverleaf	cloverleaf	NN
cord-271972-qhr6iir6	128	7	RNA	RNA	NNP
cord-271972-qhr6iir6	128	8	structure	structure	NN
cord-271972-qhr6iir6	128	9	34	34	CD
cord-271972-qhr6iir6	128	10	(	(	-LRB-
cord-271972-qhr6iir6	128	11	Figure	figure	NN
cord-271972-qhr6iir6	128	12	3(b	3(b	CD
cord-271972-qhr6iir6	128	13	)	)	-RRB-
cord-271972-qhr6iir6	128	14	)	)	-RRB-
cord-271972-qhr6iir6	128	15	.	.	.
cord-271972-qhr6iir6	129	1	Mutations	mutation	NNS
cord-271972-qhr6iir6	129	2	in	in	IN
cord-271972-qhr6iir6	129	3	this	this	DT
cord-271972-qhr6iir6	129	4	structure	structure	NN
cord-271972-qhr6iir6	129	5	and	and	CC
cord-271972-qhr6iir6	129	6	consequent	consequent	JJ
cord-271972-qhr6iir6	129	7	loss	loss	NN
cord-271972-qhr6iir6	129	8	of	of	IN
cord-271972-qhr6iir6	129	9	the	the	DT
cord-271972-qhr6iir6	129	10	RNP	RNP	NNP
cord-271972-qhr6iir6	129	11	adversely	adversely	RB
cord-271972-qhr6iir6	129	12	affect	affect	VBP
cord-271972-qhr6iir6	129	13	PV	PV	NNP
cord-271972-qhr6iir6	129	14	RNA	RNA	NNP
cord-271972-qhr6iir6	129	15	stability	stability	NN
cord-271972-qhr6iir6	129	16	,	,	,
cord-271972-qhr6iir6	129	17	possibly	possibly	RB
cord-271972-qhr6iir6	129	18	as	as	IN
cord-271972-qhr6iir6	129	19	a	a	DT
cord-271972-qhr6iir6	129	20	consequence	consequence	NN
cord-271972-qhr6iir6	129	21	of	of	IN
cord-271972-qhr6iir6	129	22	increasing	increase	VBG
cord-271972-qhr6iir6	129	23	susceptibility	susceptibility	NN
cord-271972-qhr6iir6	129	24	to	to	IN
cord-271972-qhr6iir6	129	25	Xrn1-mediated	xrn1-mediated	JJ
cord-271972-qhr6iir6	129	26	degradation	degradation	NN
cord-271972-qhr6iir6	129	27	.	.	.
cord-271972-qhr6iir6	130	1	35	35	CD
cord-271972-qhr6iir6	131	1	This	this	DT
cord-271972-qhr6iir6	131	2	strategy	strategy	NN
cord-271972-qhr6iir6	131	3	is	be	VBZ
cord-271972-qhr6iir6	131	4	probably	probably	RB
cord-271972-qhr6iir6	131	5	common	common	JJ
cord-271972-qhr6iir6	131	6	to	to	IN
cord-271972-qhr6iir6	131	7	many	many	JJ
cord-271972-qhr6iir6	131	8	other	other	JJ
cord-271972-qhr6iir6	131	9	members	member	NNS
cord-271972-qhr6iir6	131	10	of	of	IN
cord-271972-qhr6iir6	131	11	the	the	DT
cord-271972-qhr6iir6	131	12	Picornaviridae	Picornaviridae	NNP
cord-271972-qhr6iir6	131	13	family	family	NN
cord-271972-qhr6iir6	131	14	,	,	,
cord-271972-qhr6iir6	131	15	as	as	IN
cord-271972-qhr6iir6	131	16	the	the	DT
cord-271972-qhr6iir6	131	17	5	5	CD
cord-271972-qhr6iir6	131	18	cloverleaf	cloverleaf	NN
cord-271972-qhr6iir6	131	19	structure	structure	NN
cord-271972-qhr6iir6	131	20	is	be	VBZ
cord-271972-qhr6iir6	131	21	highly	highly	RB
cord-271972-qhr6iir6	131	22	conserved	conserve	VBN
cord-271972-qhr6iir6	131	23	.	.	.
cord-271972-qhr6iir6	132	1	36	36	CD
cord-271972-qhr6iir6	133	1	Interestingly	interestingly	RB
cord-271972-qhr6iir6	133	2	,	,	,
cord-271972-qhr6iir6	133	3	some	some	DT
cord-271972-qhr6iir6	133	4	viruses	virus	NNS
cord-271972-qhr6iir6	133	5	instead	instead	RB
cord-271972-qhr6iir6	133	6	exploit	exploit	VBP
cord-271972-qhr6iir6	133	7	the	the	DT
cord-271972-qhr6iir6	133	8	activity	activity	NN
cord-271972-qhr6iir6	133	9	of	of	IN
cord-271972-qhr6iir6	133	10	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	133	11	(	(	-LRB-
cord-271972-qhr6iir6	133	12	Figure	figure	NN
cord-271972-qhr6iir6	133	13	3(c	3(c	CD
cord-271972-qhr6iir6	133	14	)	)	-RRB-
cord-271972-qhr6iir6	133	15	)	)	-RRB-
cord-271972-qhr6iir6	133	16	.	.	.
cord-271972-qhr6iir6	134	1	Flaviviruses	flavivirus	NNS
cord-271972-qhr6iir6	134	2	such	such	JJ
cord-271972-qhr6iir6	134	3	as	as	IN
cord-271972-qhr6iir6	134	4	West	West	NNP
cord-271972-qhr6iir6	134	5	Nile	Nile	NNP
cord-271972-qhr6iir6	134	6	and	and	CC
cord-271972-qhr6iir6	134	7	Dengue	dengue	NN
cord-271972-qhr6iir6	134	8	viruses	virus	NNS
cord-271972-qhr6iir6	134	9	may	may	MD
cord-271972-qhr6iir6	134	10	appropriate	appropriate	VB
cord-271972-qhr6iir6	134	11	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	134	12	to	to	TO
cord-271972-qhr6iir6	134	13	produce	produce	VB
cord-271972-qhr6iir6	134	14	a	a	DT
cord-271972-qhr6iir6	134	15	3	3	CD
cord-271972-qhr6iir6	134	16	subgenomic	subgenomic	NNP
cord-271972-qhr6iir6	134	17	RNA	RNA	NNP
cord-271972-qhr6iir6	134	18	(	(	-LRB-
cord-271972-qhr6iir6	134	19	termed	term	VBN
cord-271972-qhr6iir6	134	20	sfRNA	sfRNA	NNS
cord-271972-qhr6iir6	134	21	)	)	-RRB-
cord-271972-qhr6iir6	134	22	that	that	WDT
cord-271972-qhr6iir6	134	23	plays	play	VBZ
cord-271972-qhr6iir6	134	24	an	an	DT
cord-271972-qhr6iir6	134	25	essential	essential	JJ
cord-271972-qhr6iir6	134	26	role	role	NN
cord-271972-qhr6iir6	134	27	in	in	IN
cord-271972-qhr6iir6	134	28	viral	viral	JJ
cord-271972-qhr6iir6	134	29	pathogenicity	pathogenicity	NN
cord-271972-qhr6iir6	134	30	in	in	IN
cord-271972-qhr6iir6	134	31	both	both	DT
cord-271972-qhr6iir6	134	32	cell	cell	NN
cord-271972-qhr6iir6	134	33	culture	culture	NN
cord-271972-qhr6iir6	134	34	and	and	CC
cord-271972-qhr6iir6	134	35	mice	mouse	NNS
cord-271972-qhr6iir6	134	36	.	.	.
cord-271972-qhr6iir6	135	1	37	37	CD
cord-271972-qhr6iir6	136	1	These	these	DT
cord-271972-qhr6iir6	136	2	viruses	virus	NNS
cord-271972-qhr6iir6	136	3	have	have	VBP
cord-271972-qhr6iir6	136	4	a	a	DT
cord-271972-qhr6iir6	136	5	highly	highly	RB
cord-271972-qhr6iir6	136	6	structured	structured	JJ
cord-271972-qhr6iir6	136	7	sequence	sequence	NN
cord-271972-qhr6iir6	136	8	(	(	-LRB-
cord-271972-qhr6iir6	136	9	stem	stem	NN
cord-271972-qhr6iir6	136	10	loop	loop	NN
cord-271972-qhr6iir6	136	11	II	II	NNP
cord-271972-qhr6iir6	136	12	or	or	CC
cord-271972-qhr6iir6	136	13	SLII	SLII	NNP
cord-271972-qhr6iir6	136	14	)	)	-RRB-
cord-271972-qhr6iir6	136	15	within	within	IN
cord-271972-qhr6iir6	136	16	the	the	DT
cord-271972-qhr6iir6	136	17	3	3	CD
cord-271972-qhr6iir6	136	18	UTR	UTR	NNP
cord-271972-qhr6iir6	136	19	of	of	IN
cord-271972-qhr6iir6	136	20	their	-PRON-	PRP$
cord-271972-qhr6iir6	136	21	genome	genome	NN
cord-271972-qhr6iir6	136	22	that	that	WDT
cord-271972-qhr6iir6	136	23	is	be	VBZ
cord-271972-qhr6iir6	136	24	necessary	necessary	JJ
cord-271972-qhr6iir6	136	25	for	for	IN
cord-271972-qhr6iir6	136	26	the	the	DT
cord-271972-qhr6iir6	136	27	production	production	NN
cord-271972-qhr6iir6	136	28	of	of	IN
cord-271972-qhr6iir6	136	29	the	the	DT
cord-271972-qhr6iir6	136	30	sfRNA	sfrna	NN
cord-271972-qhr6iir6	136	31	.	.	.
cord-271972-qhr6iir6	137	1	Depletion	depletion	NN
cord-271972-qhr6iir6	137	2	of	of	IN
cord-271972-qhr6iir6	137	3	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	137	4	prevents	prevent	VBZ
cord-271972-qhr6iir6	137	5	production	production	NN
cord-271972-qhr6iir6	137	6	of	of	IN
cord-271972-qhr6iir6	137	7	sfRNA	sfrna	NN
cord-271972-qhr6iir6	137	8	,	,	,
cord-271972-qhr6iir6	137	9	suggesting	suggest	VBG
cord-271972-qhr6iir6	137	10	that	that	IN
cord-271972-qhr6iir6	137	11	sfRNA	sfrna	NN
cord-271972-qhr6iir6	137	12	is	be	VBZ
cord-271972-qhr6iir6	137	13	a	a	DT
cord-271972-qhr6iir6	137	14	product	product	NN
cord-271972-qhr6iir6	137	15	of	of	IN
cord-271972-qhr6iir6	137	16	Xrn1-mediated	xrn1-mediated	JJ
cord-271972-qhr6iir6	137	17	degradation	degradation	NN
cord-271972-qhr6iir6	137	18	of	of	IN
cord-271972-qhr6iir6	137	19	the	the	DT
cord-271972-qhr6iir6	137	20	viral	viral	JJ
cord-271972-qhr6iir6	137	21	genomic	genomic	JJ
cord-271972-qhr6iir6	137	22	RNA	rna	NN
cord-271972-qhr6iir6	137	23	upstream	upstream	RB
cord-271972-qhr6iir6	137	24	of	of	IN
cord-271972-qhr6iir6	137	25	SLII	SLII	NNP
cord-271972-qhr6iir6	137	26	.	.	.
cord-271972-qhr6iir6	138	1	In	in	IN
cord-271972-qhr6iir6	138	2	turn	turn	NN
cord-271972-qhr6iir6	138	3	,	,	,
cord-271972-qhr6iir6	138	4	this	this	DT
cord-271972-qhr6iir6	138	5	indicates	indicate	VBZ
cord-271972-qhr6iir6	138	6	that	that	IN
cord-271972-qhr6iir6	138	7	the	the	DT
cord-271972-qhr6iir6	138	8	SLII	SLII	NNP
cord-271972-qhr6iir6	138	9	element	element	NN
cord-271972-qhr6iir6	138	10	can	can	MD
cord-271972-qhr6iir6	138	11	stall	stall	VB
cord-271972-qhr6iir6	138	12	Xrn1	xrn1	JJ
cord-271972-qhr6iir6	138	13	activity	activity	NN
cord-271972-qhr6iir6	138	14	.	.	.
cord-271972-qhr6iir6	139	1	Because	because	IN
cord-271972-qhr6iir6	139	2	no	no	DT
cord-271972-qhr6iir6	139	3	other	other	JJ
cord-271972-qhr6iir6	139	4	Xrn1-blocking	xrn1-blocking	NN
cord-271972-qhr6iir6	139	5	element	element	NN
cord-271972-qhr6iir6	139	6	has	have	VBZ
cord-271972-qhr6iir6	139	7	been	be	VBN
cord-271972-qhr6iir6	139	8	described	describe	VBN
cord-271972-qhr6iir6	139	9	in	in	IN
cord-271972-qhr6iir6	139	10	mammalian	mammalian	JJ
cord-271972-qhr6iir6	139	11	cells	cell	NNS
cord-271972-qhr6iir6	139	12	,	,	,
cord-271972-qhr6iir6	139	13	the	the	DT
cord-271972-qhr6iir6	139	14	SLII	SLII	NNP
cord-271972-qhr6iir6	139	15	element	element	NN
cord-271972-qhr6iir6	139	16	will	will	MD
cord-271972-qhr6iir6	139	17	likely	likely	RB
cord-271972-qhr6iir6	139	18	prove	prove	VB
cord-271972-qhr6iir6	139	19	a	a	DT
cord-271972-qhr6iir6	139	20	valuable	valuable	JJ
cord-271972-qhr6iir6	139	21	tool	tool	NN
cord-271972-qhr6iir6	139	22	to	to	TO
cord-271972-qhr6iir6	139	23	study	study	VB
cord-271972-qhr6iir6	139	24	Xrn1-mediated	xrn1-mediated	JJ
cord-271972-qhr6iir6	139	25	degradation	degradation	NN
cord-271972-qhr6iir6	139	26	both	both	DT
cord-271972-qhr6iir6	139	27	in	in	IN
cord-271972-qhr6iir6	139	28	the	the	DT
cord-271972-qhr6iir6	139	29	context	context	NN
cord-271972-qhr6iir6	139	30	of	of	IN
cord-271972-qhr6iir6	139	31	viral	viral	JJ
cord-271972-qhr6iir6	139	32	infections	infection	NNS
cord-271972-qhr6iir6	139	33	and	and	CC
cord-271972-qhr6iir6	139	34	in	in	IN
cord-271972-qhr6iir6	139	35	uninfected	uninfected	JJ
cord-271972-qhr6iir6	139	36	cells	cell	NNS
cord-271972-qhr6iir6	139	37	.	.	.
cord-271972-qhr6iir6	140	1	The	the	DT
cord-271972-qhr6iir6	140	2	exosome	exosome	NN
cord-271972-qhr6iir6	140	3	,	,	,
cord-271972-qhr6iir6	140	4	a	a	DT
cord-271972-qhr6iir6	140	5	multisubunit	multisubunit	NN
cord-271972-qhr6iir6	140	6	protein	protein	NN
cord-271972-qhr6iir6	140	7	complex	complex	NN
cord-271972-qhr6iir6	140	8	with	with	IN
cord-271972-qhr6iir6	140	9	3	3	CD
cord-271972-qhr6iir6	140	10	→5	→5	JJ
cord-271972-qhr6iir6	140	11	exonucleolytic	exonucleolytic	JJ
cord-271972-qhr6iir6	140	12	activity	activity	NN
cord-271972-qhr6iir6	140	13	,	,	,
cord-271972-qhr6iir6	140	14	is	be	VBZ
cord-271972-qhr6iir6	140	15	the	the	DT
cord-271972-qhr6iir6	140	16	major	major	JJ
cord-271972-qhr6iir6	140	17	driver	driver	NN
cord-271972-qhr6iir6	140	18	of	of	IN
cord-271972-qhr6iir6	140	19	RNA	RNA	NNP
cord-271972-qhr6iir6	140	20	degradation	degradation	NN
cord-271972-qhr6iir6	140	21	from	from	IN
cord-271972-qhr6iir6	140	22	the	the	DT
cord-271972-qhr6iir6	140	23	3	3	CD
cord-271972-qhr6iir6	140	24	end	end	NN
cord-271972-qhr6iir6	140	25	(	(	-LRB-
cord-271972-qhr6iir6	140	26	Figure	figure	NN
cord-271972-qhr6iir6	140	27	1	1	CD
cord-271972-qhr6iir6	140	28	)	)	-RRB-
cord-271972-qhr6iir6	140	29	.	.	.
cord-271972-qhr6iir6	141	1	In	in	IN
cord-271972-qhr6iir6	141	2	the	the	DT
cord-271972-qhr6iir6	141	3	cytoplasm	cytoplasm	NN
cord-271972-qhr6iir6	141	4	,	,	,
cord-271972-qhr6iir6	141	5	this	this	DT
cord-271972-qhr6iir6	141	6	complex	complex	NN
cord-271972-qhr6iir6	141	7	participates	participate	VBZ
cord-271972-qhr6iir6	141	8	in	in	IN
cord-271972-qhr6iir6	141	9	mRNA	mrna	NN
cord-271972-qhr6iir6	141	10	turnover	turnover	NN
cord-271972-qhr6iir6	141	11	after	after	IN
cord-271972-qhr6iir6	141	12	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	141	13	,	,	,
cord-271972-qhr6iir6	141	14	whereas	whereas	IN
cord-271972-qhr6iir6	141	15	in	in	IN
cord-271972-qhr6iir6	141	16	the	the	DT
cord-271972-qhr6iir6	141	17	nucleus	nucleus	NN
cord-271972-qhr6iir6	141	18	it	-PRON-	PRP
cord-271972-qhr6iir6	141	19	plays	play	VBZ
cord-271972-qhr6iir6	141	20	an	an	DT
cord-271972-qhr6iir6	141	21	essential	essential	JJ
cord-271972-qhr6iir6	141	22	role	role	NN
cord-271972-qhr6iir6	141	23	in	in	IN
cord-271972-qhr6iir6	141	24	RNA	RNA	NNP
cord-271972-qhr6iir6	141	25	processing	processing	NN
cord-271972-qhr6iir6	141	26	and	and	CC
cord-271972-qhr6iir6	141	27	quality	quality	NN
cord-271972-qhr6iir6	141	28	control	control	NN
cord-271972-qhr6iir6	141	29	.	.	.
cord-271972-qhr6iir6	142	1	38	38	CD
cord-271972-qhr6iir6	142	2	Little	Little	NNP
cord-271972-qhr6iir6	142	3	is	be	VBZ
cord-271972-qhr6iir6	142	4	currently	currently	RB
cord-271972-qhr6iir6	142	5	known	know	VBN
cord-271972-qhr6iir6	142	6	about	about	IN
cord-271972-qhr6iir6	142	7	the	the	DT
cord-271972-qhr6iir6	142	8	interaction	interaction	NN
cord-271972-qhr6iir6	142	9	of	of	IN
cord-271972-qhr6iir6	142	10	the	the	DT
cord-271972-qhr6iir6	142	11	exosome	exosome	NN
cord-271972-qhr6iir6	142	12	with	with	IN
cord-271972-qhr6iir6	142	13	viruses	virus	NNS
cord-271972-qhr6iir6	142	14	.	.	.
cord-271972-qhr6iir6	143	1	However	however	RB
cord-271972-qhr6iir6	143	2	,	,	,
cord-271972-qhr6iir6	143	3	the	the	DT
cord-271972-qhr6iir6	143	4	zinc	zinc	NN
cord-271972-qhr6iir6	143	5	-	-	HYPH
cord-271972-qhr6iir6	143	6	finger	finger	NN
cord-271972-qhr6iir6	143	7	antiviral	antiviral	JJ
cord-271972-qhr6iir6	143	8	protein	protein	NN
cord-271972-qhr6iir6	143	9	(	(	-LRB-
cord-271972-qhr6iir6	143	10	ZAP	ZAP	NNP
cord-271972-qhr6iir6	143	11	)	)	-RRB-
cord-271972-qhr6iir6	143	12	,	,	,
cord-271972-qhr6iir6	143	13	an	an	DT
cord-271972-qhr6iir6	143	14	important	important	JJ
cord-271972-qhr6iir6	143	15	mediator	mediator	NN
cord-271972-qhr6iir6	143	16	of	of	IN
cord-271972-qhr6iir6	143	17	cellular	cellular	JJ
cord-271972-qhr6iir6	143	18	response	response	NN
cord-271972-qhr6iir6	143	19	to	to	IN
cord-271972-qhr6iir6	143	20	retroviruses	retrovirus	NNS
cord-271972-qhr6iir6	143	21	,	,	,
cord-271972-qhr6iir6	143	22	39	39	CD
cord-271972-qhr6iir6	143	23	alphaviruses	alphavirus	NNS
cord-271972-qhr6iir6	143	24	,	,	,
cord-271972-qhr6iir6	143	25	40	40	CD
cord-271972-qhr6iir6	143	26	and	and	CC
cord-271972-qhr6iir6	143	27	filoviruses	filovirus	NNS
cord-271972-qhr6iir6	143	28	,	,	,
cord-271972-qhr6iir6	143	29	41	41	CD
cord-271972-qhr6iir6	143	30	has	have	VBZ
cord-271972-qhr6iir6	143	31	been	be	VBN
cord-271972-qhr6iir6	143	32	shown	show	VBN
cord-271972-qhr6iir6	143	33	to	to	TO
cord-271972-qhr6iir6	143	34	bind	bind	VB
cord-271972-qhr6iir6	143	35	the	the	DT
cord-271972-qhr6iir6	143	36	hRrp46	hrrp46	CD
cord-271972-qhr6iir6	143	37	component	component	NN
cord-271972-qhr6iir6	143	38	of	of	IN
cord-271972-qhr6iir6	143	39	the	the	DT
cord-271972-qhr6iir6	143	40	exosome	exosome	NN
cord-271972-qhr6iir6	143	41	and	and	CC
cord-271972-qhr6iir6	143	42	to	to	TO
cord-271972-qhr6iir6	143	43	recruit	recruit	VB
cord-271972-qhr6iir6	143	44	the	the	DT
cord-271972-qhr6iir6	143	45	complex	complex	NN
cord-271972-qhr6iir6	143	46	to	to	IN
cord-271972-qhr6iir6	143	47	viral	viral	JJ
cord-271972-qhr6iir6	143	48	mRNAs	mrnas	$
cord-271972-qhr6iir6	143	49	to	to	TO
cord-271972-qhr6iir6	143	50	promote	promote	VB
cord-271972-qhr6iir6	143	51	their	-PRON-	PRP$
cord-271972-qhr6iir6	143	52	degradation	degradation	NN
cord-271972-qhr6iir6	143	53	.	.	.
cord-271972-qhr6iir6	144	1	42	42	CD
cord-271972-qhr6iir6	144	2	Depletion	depletion	NN
cord-271972-qhr6iir6	144	3	of	of	IN
cord-271972-qhr6iir6	144	4	the	the	DT
cord-271972-qhr6iir6	144	5	exosome	exosome	NN
cord-271972-qhr6iir6	144	6	using	use	VBG
cord-271972-qhr6iir6	144	7	siRNAs	siRNAs	NNP
cord-271972-qhr6iir6	144	8	directed	direct	VBN
cord-271972-qhr6iir6	144	9	against	against	IN
cord-271972-qhr6iir6	144	10	the	the	DT
cord-271972-qhr6iir6	144	11	hRrp41	hRrp41	NNP
cord-271972-qhr6iir6	144	12	and	and	CC
cord-271972-qhr6iir6	144	13	hRrp46	hRrp46	NNP
cord-271972-qhr6iir6	144	14	subunits	subunit	NNS
cord-271972-qhr6iir6	144	15	reduces	reduce	VBZ
cord-271972-qhr6iir6	144	16	turnover	turnover	NN
cord-271972-qhr6iir6	144	17	of	of	IN
cord-271972-qhr6iir6	144	18	reporter	reporter	NN
cord-271972-qhr6iir6	144	19	RNAs	rna	NNS
cord-271972-qhr6iir6	144	20	by	by	IN
cord-271972-qhr6iir6	144	21	ZAP	ZAP	NNP
cord-271972-qhr6iir6	144	22	,	,	,
cord-271972-qhr6iir6	144	23	suggesting	suggest	VBG
cord-271972-qhr6iir6	144	24	that	that	IN
cord-271972-qhr6iir6	144	25	exosome	exosome	NN
cord-271972-qhr6iir6	144	26	activity	activity	NN
cord-271972-qhr6iir6	144	27	is	be	VBZ
cord-271972-qhr6iir6	144	28	an	an	DT
cord-271972-qhr6iir6	144	29	integral	integral	JJ
cord-271972-qhr6iir6	144	30	component	component	NN
cord-271972-qhr6iir6	144	31	of	of	IN
cord-271972-qhr6iir6	144	32	ZAP	ZAP	NNP
cord-271972-qhr6iir6	144	33	function	function	NN
cord-271972-qhr6iir6	144	34	.	.	.
cord-271972-qhr6iir6	145	1	ZAP	ZAP	NNP
cord-271972-qhr6iir6	145	2	binds	bind	VBZ
cord-271972-qhr6iir6	145	3	viral	viral	JJ
cord-271972-qhr6iir6	145	4	RNAs	rna	NNS
cord-271972-qhr6iir6	145	5	in	in	IN
cord-271972-qhr6iir6	145	6	a	a	DT
cord-271972-qhr6iir6	145	7	sequence	sequence	NN
cord-271972-qhr6iir6	145	8	-	-	HYPH
cord-271972-qhr6iir6	145	9	specific	specific	JJ
cord-271972-qhr6iir6	145	10	manner	manner	NN
cord-271972-qhr6iir6	145	11	,	,	,
cord-271972-qhr6iir6	145	12	perhaps	perhaps	RB
cord-271972-qhr6iir6	145	13	explaining	explain	VBG
cord-271972-qhr6iir6	145	14	why	why	WRB
cord-271972-qhr6iir6	145	15	this	this	DT
cord-271972-qhr6iir6	145	16	protein	protein	NN
cord-271972-qhr6iir6	145	17	is	be	VBZ
cord-271972-qhr6iir6	145	18	not	not	RB
cord-271972-qhr6iir6	145	19	a	a	DT
cord-271972-qhr6iir6	145	20	broad	broad	JJ
cord-271972-qhr6iir6	145	21	-	-	HYPH
cord-271972-qhr6iir6	145	22	spectrum	spectrum	NN
cord-271972-qhr6iir6	145	23	viral	viral	JJ
cord-271972-qhr6iir6	145	24	inhibitor	inhibitor	NN
cord-271972-qhr6iir6	145	25	.	.	.
cord-271972-qhr6iir6	146	1	43	43	CD
cord-271972-qhr6iir6	147	1	However	however	RB
cord-271972-qhr6iir6	147	2	,	,	,
cord-271972-qhr6iir6	147	3	the	the	DT
cord-271972-qhr6iir6	147	4	absence	absence	NN
cord-271972-qhr6iir6	147	5	of	of	IN
cord-271972-qhr6iir6	147	6	significant	significant	JJ
cord-271972-qhr6iir6	147	7	homology	homology	NN
cord-271972-qhr6iir6	147	8	between	between	IN
cord-271972-qhr6iir6	147	9	the	the	DT
cord-271972-qhr6iir6	147	10	various	various	JJ
cord-271972-qhr6iir6	147	11	viral	viral	JJ
cord-271972-qhr6iir6	147	12	sequences	sequence	NNS
cord-271972-qhr6iir6	147	13	bound	bind	VBN
cord-271972-qhr6iir6	147	14	by	by	IN
cord-271972-qhr6iir6	147	15	ZAP	ZAP	NNP
cord-271972-qhr6iir6	147	16	implicates	implicate	VBZ
cord-271972-qhr6iir6	147	17	RNA	RNA	NNP
cord-271972-qhr6iir6	147	18	structure	structure	NN
cord-271972-qhr6iir6	147	19	as	as	IN
cord-271972-qhr6iir6	147	20	the	the	DT
cord-271972-qhr6iir6	147	21	primary	primary	JJ
cord-271972-qhr6iir6	147	22	determinant	determinant	NN
cord-271972-qhr6iir6	147	23	for	for	IN
cord-271972-qhr6iir6	147	24	recognition	recognition	NN
cord-271972-qhr6iir6	147	25	.	.	.
cord-271972-qhr6iir6	148	1	An	an	DT
cord-271972-qhr6iir6	148	2	important	important	JJ
cord-271972-qhr6iir6	148	3	next	next	JJ
cord-271972-qhr6iir6	148	4	step	step	NN
cord-271972-qhr6iir6	148	5	will	will	MD
cord-271972-qhr6iir6	148	6	be	be	VB
cord-271972-qhr6iir6	148	7	to	to	TO
cord-271972-qhr6iir6	148	8	directly	directly	RB
cord-271972-qhr6iir6	148	9	test	test	VB
cord-271972-qhr6iir6	148	10	whether	whether	IN
cord-271972-qhr6iir6	148	11	exosome	exosome	NNP
cord-271972-qhr6iir6	148	12	depletion	depletion	NN
cord-271972-qhr6iir6	148	13	rescues	rescue	VBZ
cord-271972-qhr6iir6	148	14	viral	viral	JJ
cord-271972-qhr6iir6	148	15	replication	replication	NN
cord-271972-qhr6iir6	148	16	defects	defect	NNS
cord-271972-qhr6iir6	148	17	in	in	IN
cord-271972-qhr6iir6	148	18	ZAP	ZAP	NNP
cord-271972-qhr6iir6	148	19	-	-	HYPH
cord-271972-qhr6iir6	148	20	expressing	express	VBG
cord-271972-qhr6iir6	148	21	cells	cell	NNS
cord-271972-qhr6iir6	148	22	.	.	.
cord-271972-qhr6iir6	149	1	These	these	DT
cord-271972-qhr6iir6	149	2	findings	finding	NNS
cord-271972-qhr6iir6	149	3	suggest	suggest	VBP
cord-271972-qhr6iir6	149	4	a	a	DT
cord-271972-qhr6iir6	149	5	role	role	NN
cord-271972-qhr6iir6	149	6	for	for	IN
cord-271972-qhr6iir6	149	7	the	the	DT
cord-271972-qhr6iir6	149	8	exosome	exosome	NN
cord-271972-qhr6iir6	149	9	in	in	IN
cord-271972-qhr6iir6	149	10	controlling	control	VBG
cord-271972-qhr6iir6	149	11	viral	viral	JJ
cord-271972-qhr6iir6	149	12	infection	infection	NN
cord-271972-qhr6iir6	149	13	.	.	.
cord-271972-qhr6iir6	150	1	In	in	IN
cord-271972-qhr6iir6	150	2	contrast	contrast	NN
cord-271972-qhr6iir6	150	3	,	,	,
cord-271972-qhr6iir6	150	4	no	no	DT
cord-271972-qhr6iir6	150	5	evidence	evidence	NN
cord-271972-qhr6iir6	150	6	currently	currently	RB
cord-271972-qhr6iir6	150	7	exists	exist	VBZ
cord-271972-qhr6iir6	150	8	for	for	IN
cord-271972-qhr6iir6	150	9	viruses	virus	NNS
cord-271972-qhr6iir6	150	10	directly	directly	RB
cord-271972-qhr6iir6	150	11	co	co	VBN
cord-271972-qhr6iir6	150	12	-	-	JJ
cord-271972-qhr6iir6	150	13	opting	opt	VBG
cord-271972-qhr6iir6	150	14	this	this	DT
cord-271972-qhr6iir6	150	15	complex	complex	NN
cord-271972-qhr6iir6	150	16	.	.	.
cord-271972-qhr6iir6	151	1	Nonetheless	nonetheless	RB
cord-271972-qhr6iir6	151	2	,	,	,
cord-271972-qhr6iir6	151	3	given	give	VBN
cord-271972-qhr6iir6	151	4	the	the	DT
cord-271972-qhr6iir6	151	5	widespread	widespread	JJ
cord-271972-qhr6iir6	151	6	roles	role	NNS
cord-271972-qhr6iir6	151	7	for	for	IN
cord-271972-qhr6iir6	151	8	the	the	DT
cord-271972-qhr6iir6	151	9	exosome	exosome	NN
cord-271972-qhr6iir6	151	10	in	in	IN
cord-271972-qhr6iir6	151	11	RNA	RNA	NNP
cord-271972-qhr6iir6	151	12	quality	quality	NN
cord-271972-qhr6iir6	151	13	control	control	NN
cord-271972-qhr6iir6	151	14	and	and	CC
cord-271972-qhr6iir6	151	15	turnover	turnover	NN
cord-271972-qhr6iir6	151	16	,	,	,
cord-271972-qhr6iir6	151	17	viruses	virus	NNS
cord-271972-qhr6iir6	151	18	presumably	presumably	RB
cord-271972-qhr6iir6	151	19	activate	activate	VBP
cord-271972-qhr6iir6	151	20	this	this	DT
cord-271972-qhr6iir6	151	21	complex	complex	NN
cord-271972-qhr6iir6	151	22	at	at	IN
cord-271972-qhr6iir6	151	23	least	least	JJS
cord-271972-qhr6iir6	151	24	indirectly	indirectly	RB
cord-271972-qhr6iir6	151	25	when	when	WRB
cord-271972-qhr6iir6	151	26	triggering	trigger	VBG
cord-271972-qhr6iir6	151	27	turnover	turnover	NN
cord-271972-qhr6iir6	151	28	of	of	IN
cord-271972-qhr6iir6	151	29	cellular	cellular	JJ
cord-271972-qhr6iir6	151	30	mRNAs	mrna	NNS
cord-271972-qhr6iir6	151	31	.	.	.
cord-271972-qhr6iir6	152	1	For	for	IN
cord-271972-qhr6iir6	152	2	example	example	NN
cord-271972-qhr6iir6	152	3	,	,	,
cord-271972-qhr6iir6	152	4	infection	infection	NN
cord-271972-qhr6iir6	152	5	by	by	IN
cord-271972-qhr6iir6	152	6	select	select	JJ
cord-271972-qhr6iir6	152	7	herpes	herpe	NNS
cord-271972-qhr6iir6	152	8	and	and	CC
cord-271972-qhr6iir6	152	9	coronaviruses	coronaviruse	NNS
cord-271972-qhr6iir6	152	10	results	result	NNS
cord-271972-qhr6iir6	152	11	in	in	IN
cord-271972-qhr6iir6	152	12	a	a	DT
cord-271972-qhr6iir6	152	13	global	global	JJ
cord-271972-qhr6iir6	152	14	destruction	destruction	NN
cord-271972-qhr6iir6	152	15	of	of	IN
cord-271972-qhr6iir6	152	16	host	host	NN
cord-271972-qhr6iir6	152	17	messages	message	NNS
cord-271972-qhr6iir6	152	18	.	.	.
cord-271972-qhr6iir6	153	1	[	[	-LRB-
cord-271972-qhr6iir6	153	2	44	44	CD
cord-271972-qhr6iir6	153	3	]	]	-RRB-
cord-271972-qhr6iir6	153	4	[	[	-LRB-
cord-271972-qhr6iir6	153	5	45	45	CD
cord-271972-qhr6iir6	153	6	]	]	-RRB-
cord-271972-qhr6iir6	154	1	[	[	-LRB-
cord-271972-qhr6iir6	154	2	46	46	CD
cord-271972-qhr6iir6	154	3	]	]	-RRB-
cord-271972-qhr6iir6	155	1	[	[	-LRB-
cord-271972-qhr6iir6	155	2	47	47	CD
cord-271972-qhr6iir6	155	3	]	]	-RRB-
cord-271972-qhr6iir6	156	1	[	[	-LRB-
cord-271972-qhr6iir6	156	2	48	48	CD
cord-271972-qhr6iir6	156	3	]	]	-RRB-
cord-271972-qhr6iir6	157	1	The	the	DT
cord-271972-qhr6iir6	157	2	exosome	exosome	NN
cord-271972-qhr6iir6	157	3	,	,	,
cord-271972-qhr6iir6	157	4	as	as	RB
cord-271972-qhr6iir6	157	5	well	well	RB
cord-271972-qhr6iir6	157	6	as	as	IN
cord-271972-qhr6iir6	157	7	other	other	JJ
cord-271972-qhr6iir6	157	8	RNA	RNA	NNP
cord-271972-qhr6iir6	157	9	turnover	turnover	NN
cord-271972-qhr6iir6	157	10	pathways	pathway	NNS
cord-271972-qhr6iir6	157	11	,	,	,
cord-271972-qhr6iir6	157	12	may	may	MD
cord-271972-qhr6iir6	157	13	contribute	contribute	VB
cord-271972-qhr6iir6	157	14	to	to	IN
cord-271972-qhr6iir6	157	15	degradation	degradation	NN
cord-271972-qhr6iir6	157	16	of	of	IN
cord-271972-qhr6iir6	157	17	full	full	JJ
cord-271972-qhr6iir6	157	18	-	-	HYPH
cord-271972-qhr6iir6	157	19	length	length	NN
cord-271972-qhr6iir6	157	20	or	or	CC
cord-271972-qhr6iir6	157	21	partially	partially	RB
cord-271972-qhr6iir6	157	22	degraded	degrade	VBN
cord-271972-qhr6iir6	157	23	mRNAs	mrna	NNS
cord-271972-qhr6iir6	157	24	in	in	IN
cord-271972-qhr6iir6	157	25	these	these	DT
cord-271972-qhr6iir6	157	26	cases	case	NNS
cord-271972-qhr6iir6	157	27	.	.	.
cord-271972-qhr6iir6	158	1	Cells	cell	NNS
cord-271972-qhr6iir6	158	2	are	be	VBP
cord-271972-qhr6iir6	158	3	equipped	equip	VBN
cord-271972-qhr6iir6	158	4	with	with	IN
cord-271972-qhr6iir6	158	5	specific	specific	JJ
cord-271972-qhr6iir6	158	6	mechanisms	mechanism	NNS
cord-271972-qhr6iir6	158	7	for	for	IN
cord-271972-qhr6iir6	158	8	the	the	DT
cord-271972-qhr6iir6	158	9	recognition	recognition	NN
cord-271972-qhr6iir6	158	10	and	and	CC
cord-271972-qhr6iir6	158	11	disposal	disposal	NN
cord-271972-qhr6iir6	158	12	of	of	IN
cord-271972-qhr6iir6	158	13	defective	defective	JJ
cord-271972-qhr6iir6	158	14	mRNAs	mrna	NNS
cord-271972-qhr6iir6	158	15	generated	generate	VBN
cord-271972-qhr6iir6	158	16	by	by	IN
cord-271972-qhr6iir6	158	17	errors	error	NNS
cord-271972-qhr6iir6	158	18	introduced	introduce	VBN
cord-271972-qhr6iir6	158	19	during	during	IN
cord-271972-qhr6iir6	158	20	transcription	transcription	NN
cord-271972-qhr6iir6	158	21	and	and	CC
cord-271972-qhr6iir6	158	22	RNA	RNA	NNP
cord-271972-qhr6iir6	158	23	processing	processing	NN
cord-271972-qhr6iir6	158	24	or	or	CC
cord-271972-qhr6iir6	158	25	as	as	IN
cord-271972-qhr6iir6	158	26	a	a	DT
cord-271972-qhr6iir6	158	27	result	result	NN
cord-271972-qhr6iir6	158	28	of	of	IN
cord-271972-qhr6iir6	158	29	mutations	mutation	NNS
cord-271972-qhr6iir6	158	30	in	in	IN
cord-271972-qhr6iir6	158	31	the	the	DT
cord-271972-qhr6iir6	158	32	DNA	dna	NN
cord-271972-qhr6iir6	158	33	sequence	sequence	NN
cord-271972-qhr6iir6	158	34	.	.	.
cord-271972-qhr6iir6	159	1	The	the	DT
cord-271972-qhr6iir6	159	2	best	well	RBS
cord-271972-qhr6iir6	159	3	characterized	characterize	VBN
cord-271972-qhr6iir6	159	4	of	of	IN
cord-271972-qhr6iir6	159	5	these	these	DT
cord-271972-qhr6iir6	159	6	pathways	pathway	NNS
cord-271972-qhr6iir6	159	7	is	be	VBZ
cord-271972-qhr6iir6	159	8	nonsense	nonsense	NN
cord-271972-qhr6iir6	159	9	-	-	HYPH
cord-271972-qhr6iir6	159	10	mediated	mediate	VBN
cord-271972-qhr6iir6	159	11	decay	decay	NN
cord-271972-qhr6iir6	159	12	(	(	-LRB-
cord-271972-qhr6iir6	159	13	NMD	NMD	NNP
cord-271972-qhr6iir6	159	14	)	)	-RRB-
cord-271972-qhr6iir6	159	15	,	,	,
cord-271972-qhr6iir6	159	16	which	which	WDT
cord-271972-qhr6iir6	159	17	targets	target	VBZ
cord-271972-qhr6iir6	159	18	mRNAs	mrna	VBD
cord-271972-qhr6iir6	159	19	harboring	harbor	VBG
cord-271972-qhr6iir6	159	20	a	a	DT
cord-271972-qhr6iir6	159	21	premature	premature	JJ
cord-271972-qhr6iir6	159	22	stop	stop	NN
cord-271972-qhr6iir6	159	23	codon	codon	NN
cord-271972-qhr6iir6	159	24	(	(	-LRB-
cord-271972-qhr6iir6	159	25	PTC	PTC	NNP
cord-271972-qhr6iir6	159	26	)	)	-RRB-
cord-271972-qhr6iir6	160	1	(	(	-LRB-
cord-271972-qhr6iir6	160	2	Figure	figure	NN
cord-271972-qhr6iir6	160	3	4	4	CD
cord-271972-qhr6iir6	160	4	)	)	-RRB-
cord-271972-qhr6iir6	160	5	.	.	.
cord-271972-qhr6iir6	161	1	The	the	DT
cord-271972-qhr6iir6	161	2	core	core	NN
cord-271972-qhr6iir6	161	3	NMD	NMD	NNP
cord-271972-qhr6iir6	161	4	effectors	effector	NNS
cord-271972-qhr6iir6	161	5	are	be	VBP
cord-271972-qhr6iir6	161	6	the	the	DT
cord-271972-qhr6iir6	161	7	Upf	Upf	NNP
cord-271972-qhr6iir6	161	8	proteins	protein	NNS
cord-271972-qhr6iir6	161	9	,	,	,
cord-271972-qhr6iir6	161	10	which	which	WDT
cord-271972-qhr6iir6	161	11	associate	associate	VBP
cord-271972-qhr6iir6	161	12	with	with	IN
cord-271972-qhr6iir6	161	13	prematurely	prematurely	RB
cord-271972-qhr6iir6	161	14	terminating	terminate	VBG
cord-271972-qhr6iir6	161	15	mRNAs	mrnas	PRP
cord-271972-qhr6iir6	161	16	and	and	CC
cord-271972-qhr6iir6	161	17	trigger	trigger	VB
cord-271972-qhr6iir6	161	18	their	-PRON-	PRP$
cord-271972-qhr6iir6	161	19	rapid	rapid	JJ
cord-271972-qhr6iir6	161	20	destruction	destruction	NN
cord-271972-qhr6iir6	161	21	.	.	.
cord-271972-qhr6iir6	162	1	Current	current	JJ
cord-271972-qhr6iir6	162	2	models	model	NNS
cord-271972-qhr6iir6	162	3	for	for	IN
cord-271972-qhr6iir6	162	4	NMD	NMD	NNP
cord-271972-qhr6iir6	162	5	activation	activation	NN
cord-271972-qhr6iir6	162	6	in	in	IN
cord-271972-qhr6iir6	162	7	human	human	JJ
cord-271972-qhr6iir6	162	8	cells	cell	NNS
cord-271972-qhr6iir6	162	9	suggest	suggest	VBP
cord-271972-qhr6iir6	162	10	that	that	IN
cord-271972-qhr6iir6	162	11	Upf1	Upf1	NNP
cord-271972-qhr6iir6	162	12	is	be	VBZ
cord-271972-qhr6iir6	162	13	recruited	recruit	VBN
cord-271972-qhr6iir6	162	14	to	to	IN
cord-271972-qhr6iir6	162	15	these	these	DT
cord-271972-qhr6iir6	162	16	aberrant	aberrant	JJ
cord-271972-qhr6iir6	162	17	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	162	18	during	during	IN
cord-271972-qhr6iir6	162	19	the	the	DT
cord-271972-qhr6iir6	162	20	initial	initial	JJ
cord-271972-qhr6iir6	162	21	round	round	NN
cord-271972-qhr6iir6	162	22	of	of	IN
cord-271972-qhr6iir6	162	23	translation	translation	NN
cord-271972-qhr6iir6	162	24	via	via	IN
cord-271972-qhr6iir6	162	25	interactions	interaction	NNS
cord-271972-qhr6iir6	162	26	with	with	IN
cord-271972-qhr6iir6	162	27	the	the	DT
cord-271972-qhr6iir6	162	28	eRF1	eRF1	NNP
cord-271972-qhr6iir6	162	29	and	and	CC
cord-271972-qhr6iir6	162	30	eRF3	eRF3	NNP
cord-271972-qhr6iir6	162	31	translation	translation	NN
cord-271972-qhr6iir6	162	32	termination	termination	NN
cord-271972-qhr6iir6	162	33	factors	factor	NNS
cord-271972-qhr6iir6	162	34	,	,	,
cord-271972-qhr6iir6	162	35	whereupon	whereupon	IN
cord-271972-qhr6iir6	162	36	other	other	JJ
cord-271972-qhr6iir6	162	37	effectors	effector	NNS
cord-271972-qhr6iir6	162	38	of	of	IN
cord-271972-qhr6iir6	162	39	NMD	NMD	NNP
cord-271972-qhr6iir6	162	40	(	(	-LRB-
cord-271972-qhr6iir6	162	41	including	include	VBG
cord-271972-qhr6iir6	162	42	Upf2	Upf2	NNP
cord-271972-qhr6iir6	162	43	,	,	,
cord-271972-qhr6iir6	162	44	Upf3	Upf3	NNP
cord-271972-qhr6iir6	162	45	,	,	,
cord-271972-qhr6iir6	162	46	and	and	CC
cord-271972-qhr6iir6	162	47	Smg	Smg	NNP
cord-271972-qhr6iir6	162	48	proteins	protein	NNS
cord-271972-qhr6iir6	162	49	)	)	-RRB-
cord-271972-qhr6iir6	162	50	join	join	VBP
cord-271972-qhr6iir6	162	51	the	the	DT
cord-271972-qhr6iir6	162	52	complex	complex	NN
cord-271972-qhr6iir6	162	53	.	.	.
cord-271972-qhr6iir6	163	1	49	49	CD
cord-271972-qhr6iir6	164	1	The	the	DT
cord-271972-qhr6iir6	164	2	aberrant	aberrant	JJ
cord-271972-qhr6iir6	164	3	mRNA	mrna	NN
cord-271972-qhr6iir6	164	4	is	be	VBZ
cord-271972-qhr6iir6	164	5	then	then	RB
cord-271972-qhr6iir6	164	6	cleaved	cleave	VBN
cord-271972-qhr6iir6	164	7	endonucleolytically	endonucleolytically	RB
cord-271972-qhr6iir6	164	8	near	near	IN
cord-271972-qhr6iir6	164	9	the	the	DT
cord-271972-qhr6iir6	164	10	PTC	PTC	NNP
cord-271972-qhr6iir6	164	11	by	by	IN
cord-271972-qhr6iir6	164	12	the	the	DT
cord-271972-qhr6iir6	164	13	NMD	NMD	NNP
cord-271972-qhr6iir6	164	14	factor	factor	NN
cord-271972-qhr6iir6	164	15	Smg6	Smg6	NNP
cord-271972-qhr6iir6	164	16	,	,	,
cord-271972-qhr6iir6	164	17	and	and	CC
cord-271972-qhr6iir6	164	18	the	the	DT
cord-271972-qhr6iir6	164	19	message	message	NN
cord-271972-qhr6iir6	164	20	body	body	NN
cord-271972-qhr6iir6	164	21	is	be	VBZ
cord-271972-qhr6iir6	164	22	degraded	degrade	VBN
cord-271972-qhr6iir6	164	23	by	by	IN
cord-271972-qhr6iir6	164	24	cellular	cellular	JJ
cord-271972-qhr6iir6	164	25	exonucleases	exonuclease	NNS
cord-271972-qhr6iir6	164	26	50	50	CD
cord-271972-qhr6iir6	164	27	,	,	,
cord-271972-qhr6iir6	164	28	51	51	CD
cord-271972-qhr6iir6	165	1	(	(	-LRB-
cord-271972-qhr6iir6	165	2	Figure	figure	NN
cord-271972-qhr6iir6	165	3	4	4	CD
cord-271972-qhr6iir6	165	4	)	)	-RRB-
cord-271972-qhr6iir6	165	5	.	.	.
cord-271972-qhr6iir6	166	1	Two	two	CD
cord-271972-qhr6iir6	166	2	features	feature	NNS
cord-271972-qhr6iir6	166	3	can	can	MD
cord-271972-qhr6iir6	166	4	mark	mark	VB
cord-271972-qhr6iir6	166	5	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	166	6	for	for	IN
cord-271972-qhr6iir6	166	7	destruction	destruction	NN
cord-271972-qhr6iir6	166	8	via	via	IN
cord-271972-qhr6iir6	166	9	the	the	DT
cord-271972-qhr6iir6	166	10	NMD	NMD	NNP
cord-271972-qhr6iir6	166	11	pathway	pathway	NN
cord-271972-qhr6iir6	166	12	.	.	.
cord-271972-qhr6iir6	167	1	In	in	IN
cord-271972-qhr6iir6	167	2	human	human	JJ
cord-271972-qhr6iir6	167	3	cells	cell	NNS
cord-271972-qhr6iir6	167	4	,	,	,
cord-271972-qhr6iir6	167	5	one	one	CD
cord-271972-qhr6iir6	167	6	important	important	JJ
cord-271972-qhr6iir6	167	7	feature	feature	NN
cord-271972-qhr6iir6	167	8	is	be	VBZ
cord-271972-qhr6iir6	167	9	the	the	DT
cord-271972-qhr6iir6	167	10	presence	presence	NN
cord-271972-qhr6iir6	167	11	of	of	IN
cord-271972-qhr6iir6	167	12	exon	exon	NN
cord-271972-qhr6iir6	167	13	-	-	HYPH
cord-271972-qhr6iir6	167	14	exon	exon	NN
cord-271972-qhr6iir6	167	15	junctions	junction	NNS
cord-271972-qhr6iir6	167	16	downstream	downstream	RB
cord-271972-qhr6iir6	167	17	of	of	IN
cord-271972-qhr6iir6	167	18	the	the	DT
cord-271972-qhr6iir6	167	19	termination	termination	NN
cord-271972-qhr6iir6	167	20	codon	codon	NN
cord-271972-qhr6iir6	167	21	,	,	,
cord-271972-qhr6iir6	167	22	as	as	IN
cord-271972-qhr6iir6	167	23	determined	determine	VBN
cord-271972-qhr6iir6	167	24	by	by	IN
cord-271972-qhr6iir6	167	25	the	the	DT
cord-271972-qhr6iir6	167	26	retention	retention	NN
cord-271972-qhr6iir6	167	27	of	of	IN
cord-271972-qhr6iir6	167	28	exon	exon	JJ
cord-271972-qhr6iir6	167	29	-	-	HYPH
cord-271972-qhr6iir6	167	30	junction	junction	NN
cord-271972-qhr6iir6	167	31	complexes	complex	NNS
cord-271972-qhr6iir6	167	32	(	(	-LRB-
cord-271972-qhr6iir6	167	33	EJCs	ejc	NNS
cord-271972-qhr6iir6	167	34	)	)	-RRB-
cord-271972-qhr6iir6	167	35	at	at	IN
cord-271972-qhr6iir6	167	36	these	these	DT
cord-271972-qhr6iir6	167	37	sites	site	NNS
cord-271972-qhr6iir6	167	38	.	.	.
cord-271972-qhr6iir6	168	1	Normally	normally	RB
cord-271972-qhr6iir6	168	2	EJCs	ejc	NNS
cord-271972-qhr6iir6	168	3	,	,	,
cord-271972-qhr6iir6	168	4	which	which	WDT
cord-271972-qhr6iir6	168	5	are	be	VBP
cord-271972-qhr6iir6	168	6	deposited	deposit	VBN
cord-271972-qhr6iir6	168	7	during	during	IN
cord-271972-qhr6iir6	168	8	splicing	splicing	NN
cord-271972-qhr6iir6	168	9	,	,	,
cord-271972-qhr6iir6	168	10	are	be	VBP
cord-271972-qhr6iir6	168	11	displaced	displace	VBN
cord-271972-qhr6iir6	168	12	from	from	IN
cord-271972-qhr6iir6	168	13	the	the	DT
cord-271972-qhr6iir6	168	14	mRNA	mrna	NN
cord-271972-qhr6iir6	168	15	by	by	IN
cord-271972-qhr6iir6	168	16	translating	translate	VBG
cord-271972-qhr6iir6	168	17	ribosomes	ribosome	NNS
cord-271972-qhr6iir6	168	18	.	.	.
cord-271972-qhr6iir6	169	1	[	[	-LRB-
cord-271972-qhr6iir6	169	2	52	52	CD
cord-271972-qhr6iir6	169	3	]	]	-RRB-
cord-271972-qhr6iir6	169	4	[	[	-LRB-
cord-271972-qhr6iir6	169	5	53	53	CD
cord-271972-qhr6iir6	169	6	]	]	-RRB-
cord-271972-qhr6iir6	170	1	[	[	-LRB-
cord-271972-qhr6iir6	170	2	54	54	CD
cord-271972-qhr6iir6	170	3	]	]	-RRB-
cord-271972-qhr6iir6	171	1	However	however	RB
cord-271972-qhr6iir6	171	2	,	,	,
cord-271972-qhr6iir6	171	3	NMD	NMD	NNP
cord-271972-qhr6iir6	171	4	can	can	MD
cord-271972-qhr6iir6	171	5	also	also	RB
cord-271972-qhr6iir6	171	6	occur	occur	VB
cord-271972-qhr6iir6	171	7	in	in	IN
cord-271972-qhr6iir6	171	8	the	the	DT
cord-271972-qhr6iir6	171	9	absence	absence	NN
cord-271972-qhr6iir6	171	10	of	of	IN
cord-271972-qhr6iir6	171	11	splicing	splicing	NN
cord-271972-qhr6iir6	171	12	,	,	,
cord-271972-qhr6iir6	171	13	suggesting	suggest	VBG
cord-271972-qhr6iir6	171	14	that	that	IN
cord-271972-qhr6iir6	171	15	downstream	downstream	JJ
cord-271972-qhr6iir6	171	16	EJCs	ejc	NNS
cord-271972-qhr6iir6	171	17	are	be	VBP
cord-271972-qhr6iir6	171	18	not	not	RB
cord-271972-qhr6iir6	171	19	always	always	RB
cord-271972-qhr6iir6	171	20	required	require	VBN
cord-271972-qhr6iir6	171	21	for	for	IN
cord-271972-qhr6iir6	171	22	activation	activation	NN
cord-271972-qhr6iir6	171	23	of	of	IN
cord-271972-qhr6iir6	171	24	NMD	NMD	NNP
cord-271972-qhr6iir6	171	25	.	.	.
cord-271972-qhr6iir6	172	1	49	49	CD
cord-271972-qhr6iir6	173	1	Indeed	indeed	RB
cord-271972-qhr6iir6	173	2	,	,	,
cord-271972-qhr6iir6	173	3	a	a	DT
cord-271972-qhr6iir6	173	4	second	second	JJ
cord-271972-qhr6iir6	173	5	determinant	determinant	NN
cord-271972-qhr6iir6	173	6	is	be	VBZ
cord-271972-qhr6iir6	173	7	the	the	DT
cord-271972-qhr6iir6	173	8	length	length	NN
cord-271972-qhr6iir6	173	9	of	of	IN
cord-271972-qhr6iir6	173	10	the	the	DT
cord-271972-qhr6iir6	173	11	3	3	CD
cord-271972-qhr6iir6	173	12	UTR	UTR	NNP
cord-271972-qhr6iir6	173	13	,	,	,
cord-271972-qhr6iir6	173	14	which	which	WDT
cord-271972-qhr6iir6	173	15	is	be	VBZ
cord-271972-qhr6iir6	173	16	monitored	monitor	VBN
cord-271972-qhr6iir6	173	17	by	by	IN
cord-271972-qhr6iir6	173	18	the	the	DT
cord-271972-qhr6iir6	173	19	proximity	proximity	NN
cord-271972-qhr6iir6	173	20	of	of	IN
cord-271972-qhr6iir6	173	21	the	the	DT
cord-271972-qhr6iir6	173	22	termination	termination	NN
cord-271972-qhr6iir6	173	23	codon	codon	NN
cord-271972-qhr6iir6	173	24	to	to	IN
cord-271972-qhr6iir6	173	25	the	the	DT
cord-271972-qhr6iir6	173	26	poly(A	poly(a	JJ
cord-271972-qhr6iir6	173	27	)	)	-RRB-
cord-271972-qhr6iir6	173	28	tail	tail	NN
cord-271972-qhr6iir6	173	29	.	.	.
cord-271972-qhr6iir6	174	1	Messages	message	NNS
cord-271972-qhr6iir6	174	2	bearing	bear	VBG
cord-271972-qhr6iir6	174	3	PTCs	ptc	NNS
cord-271972-qhr6iir6	174	4	possess	possess	VBP
cord-271972-qhr6iir6	174	5	longer	long	JJR
cord-271972-qhr6iir6	174	6	3	3	CD
cord-271972-qhr6iir6	174	7	UTRs	utr	NNS
cord-271972-qhr6iir6	174	8	than	than	IN
cord-271972-qhr6iir6	174	9	their	-PRON-	PRP$
cord-271972-qhr6iir6	174	10	wild	wild	JJ
cord-271972-qhr6iir6	174	11	-	-	HYPH
cord-271972-qhr6iir6	174	12	type	type	NN
cord-271972-qhr6iir6	174	13	counterparts	counterpart	NNS
cord-271972-qhr6iir6	174	14	and	and	CC
cord-271972-qhr6iir6	174	15	this	this	DT
cord-271972-qhr6iir6	174	16	appears	appear	VBZ
cord-271972-qhr6iir6	174	17	to	to	TO
cord-271972-qhr6iir6	174	18	decrease	decrease	VB
cord-271972-qhr6iir6	174	19	the	the	DT
cord-271972-qhr6iir6	174	20	efficiency	efficiency	NN
cord-271972-qhr6iir6	174	21	of	of	IN
cord-271972-qhr6iir6	174	22	translation	translation	NN
cord-271972-qhr6iir6	174	23	termination	termination	NN
cord-271972-qhr6iir6	174	24	and	and	CC
cord-271972-qhr6iir6	174	25	facilitate	facilitate	VB
cord-271972-qhr6iir6	174	26	Upf1	Upf1	NNP
cord-271972-qhr6iir6	174	27	recruitment	recruitment	NN
cord-271972-qhr6iir6	174	28	,	,	,
cord-271972-qhr6iir6	174	29	even	even	RB
cord-271972-qhr6iir6	174	30	in	in	IN
cord-271972-qhr6iir6	174	31	the	the	DT
cord-271972-qhr6iir6	174	32	absence	absence	NN
cord-271972-qhr6iir6	174	33	of	of	IN
cord-271972-qhr6iir6	174	34	downstream	downstream	JJ
cord-271972-qhr6iir6	174	35	EJCs	ejc	NNS
cord-271972-qhr6iir6	174	36	.	.	.
cord-271972-qhr6iir6	175	1	[	[	-LRB-
cord-271972-qhr6iir6	175	2	55	55	CD
cord-271972-qhr6iir6	175	3	]	]	-RRB-
cord-271972-qhr6iir6	175	4	[	[	-LRB-
cord-271972-qhr6iir6	175	5	56	56	CD
cord-271972-qhr6iir6	175	6	]	]	-RRB-
cord-271972-qhr6iir6	176	1	[	[	-LRB-
cord-271972-qhr6iir6	176	2	57	57	CD
cord-271972-qhr6iir6	176	3	]	]	-RRB-
cord-271972-qhr6iir6	176	4	NMD	NMD	NNP
cord-271972-qhr6iir6	176	5	represents	represent	VBZ
cord-271972-qhr6iir6	176	6	a	a	DT
cord-271972-qhr6iir6	176	7	potentially	potentially	RB
cord-271972-qhr6iir6	176	8	formidable	formidable	JJ
cord-271972-qhr6iir6	176	9	obstacle	obstacle	NN
cord-271972-qhr6iir6	176	10	for	for	IN
cord-271972-qhr6iir6	176	11	viruses	virus	NNS
cord-271972-qhr6iir6	176	12	,	,	,
cord-271972-qhr6iir6	176	13	many	many	JJ
cord-271972-qhr6iir6	176	14	of	of	IN
cord-271972-qhr6iir6	176	15	which	which	WDT
cord-271972-qhr6iir6	176	16	encode	encode	VBP
cord-271972-qhr6iir6	176	17	polycistronic	polycistronic	JJ
cord-271972-qhr6iir6	176	18	transcripts	transcript	NNS
cord-271972-qhr6iir6	176	19	that	that	WDT
cord-271972-qhr6iir6	176	20	would	would	MD
cord-271972-qhr6iir6	176	21	presumably	presumably	RB
cord-271972-qhr6iir6	176	22	be	be	VB
cord-271972-qhr6iir6	176	23	viewed	view	VBN
cord-271972-qhr6iir6	176	24	by	by	IN
cord-271972-qhr6iir6	176	25	the	the	DT
cord-271972-qhr6iir6	176	26	cellular	cellular	JJ
cord-271972-qhr6iir6	176	27	NMD	NMD	NNP
cord-271972-qhr6iir6	176	28	machinery	machinery	NN
cord-271972-qhr6iir6	176	29	as	as	IN
cord-271972-qhr6iir6	176	30	having	have	VBG
cord-271972-qhr6iir6	176	31	aberrantly	aberrantly	RB
cord-271972-qhr6iir6	176	32	long	long	JJ
cord-271972-qhr6iir6	176	33	3	3	CD
cord-271972-qhr6iir6	176	34	UTRs	utr	NNS
cord-271972-qhr6iir6	176	35	.	.	.
cord-271972-qhr6iir6	177	1	Additionally	additionally	RB
cord-271972-qhr6iir6	177	2	,	,	,
cord-271972-qhr6iir6	177	3	viruses	virus	NNS
cord-271972-qhr6iir6	177	4	frequently	frequently	RB
cord-271972-qhr6iir6	177	5	use	use	VBP
cord-271972-qhr6iir6	177	6	alternative	alternative	JJ
cord-271972-qhr6iir6	177	7	splicing	splicing	NN
cord-271972-qhr6iir6	177	8	to	to	TO
cord-271972-qhr6iir6	177	9	maximize	maximize	VB
cord-271972-qhr6iir6	177	10	coding	code	VBG
cord-271972-qhr6iir6	177	11	potential	potential	NN
cord-271972-qhr6iir6	177	12	,	,	,
cord-271972-qhr6iir6	177	13	possibly	possibly	RB
cord-271972-qhr6iir6	177	14	creating	create	VBG
cord-271972-qhr6iir6	177	15	spliced	splice	VBN
cord-271972-qhr6iir6	177	16	variants	variant	NNS
cord-271972-qhr6iir6	177	17	with	with	IN
cord-271972-qhr6iir6	177	18	EJC	EJC	NNP
cord-271972-qhr6iir6	177	19	components	component	NNS
cord-271972-qhr6iir6	177	20	remaining	remain	VBG
cord-271972-qhr6iir6	177	21	downstream	downstream	NN
cord-271972-qhr6iir6	177	22	of	of	IN
cord-271972-qhr6iir6	177	23	the	the	DT
cord-271972-qhr6iir6	177	24	stop	stop	NN
cord-271972-qhr6iir6	177	25	codon	codon	NN
cord-271972-qhr6iir6	177	26	used	use	VBN
cord-271972-qhr6iir6	177	27	by	by	IN
cord-271972-qhr6iir6	177	28	the	the	DT
cord-271972-qhr6iir6	177	29	5	5	CD
cord-271972-qhr6iir6	177	30	ORF	ORF	NNP
cord-271972-qhr6iir6	177	31	.	.	.
cord-271972-qhr6iir6	178	1	One	one	CD
cord-271972-qhr6iir6	178	2	way	way	NN
cord-271972-qhr6iir6	178	3	viruses	virus	NNS
cord-271972-qhr6iir6	178	4	may	may	MD
cord-271972-qhr6iir6	178	5	escape	escape	VB
cord-271972-qhr6iir6	178	6	NMD	NMD	NNP
cord-271972-qhr6iir6	178	7	is	be	VBZ
cord-271972-qhr6iir6	178	8	by	by	IN
cord-271972-qhr6iir6	178	9	tightly	tightly	RB
cord-271972-qhr6iir6	178	10	regulating	regulate	VBG
cord-271972-qhr6iir6	178	11	their	-PRON-	PRP$
cord-271972-qhr6iir6	178	12	splicing	splicing	NN
cord-271972-qhr6iir6	178	13	pattern	pattern	NN
cord-271972-qhr6iir6	178	14	,	,	,
cord-271972-qhr6iir6	178	15	as	as	IN
cord-271972-qhr6iir6	178	16	is	be	VBZ
cord-271972-qhr6iir6	178	17	the	the	DT
cord-271972-qhr6iir6	178	18	case	case	NN
cord-271972-qhr6iir6	178	19	with	with	IN
cord-271972-qhr6iir6	178	20	human	human	JJ
cord-271972-qhr6iir6	178	21	immunodeficiency	immunodeficiency	NN
cord-271972-qhr6iir6	178	22	virus	virus	NN
cord-271972-qhr6iir6	178	23	1	1	CD
cord-271972-qhr6iir6	178	24	(	(	-LRB-
cord-271972-qhr6iir6	178	25	HIV-1	HIV-1	NNP
cord-271972-qhr6iir6	178	26	)	)	-RRB-
cord-271972-qhr6iir6	178	27	.	.	.
cord-271972-qhr6iir6	179	1	58	58	CD
cord-271972-qhr6iir6	180	1	The	the	DT
cord-271972-qhr6iir6	180	2	sole	sole	JJ
cord-271972-qhr6iir6	180	3	HIV-1	HIV-1	NNP
cord-271972-qhr6iir6	180	4	transcript	transcript	NN
cord-271972-qhr6iir6	180	5	is	be	VBZ
cord-271972-qhr6iir6	180	6	alternatively	alternatively	RB
cord-271972-qhr6iir6	180	7	spliced	splice	VBN
cord-271972-qhr6iir6	180	8	to	to	TO
cord-271972-qhr6iir6	180	9	generate	generate	VB
cord-271972-qhr6iir6	180	10	more	more	JJR
cord-271972-qhr6iir6	180	11	than	than	IN
cord-271972-qhr6iir6	180	12	30	30	CD
cord-271972-qhr6iir6	180	13	mRNAs	mrna	NNS
cord-271972-qhr6iir6	180	14	.	.	.
cord-271972-qhr6iir6	181	1	The	the	DT
cord-271972-qhr6iir6	181	2	genes	gene	NNS
cord-271972-qhr6iir6	181	3	are	be	VBP
cord-271972-qhr6iir6	181	4	always	always	RB
cord-271972-qhr6iir6	181	5	spliced	splice	VBN
cord-271972-qhr6iir6	181	6	out	out	RP
cord-271972-qhr6iir6	181	7	sequentially	sequentially	RB
cord-271972-qhr6iir6	181	8	in	in	IN
cord-271972-qhr6iir6	181	9	a	a	DT
cord-271972-qhr6iir6	181	10	5	5	CD
cord-271972-qhr6iir6	181	11	→3	→3	NNS
cord-271972-qhr6iir6	181	12	order	order	NN
cord-271972-qhr6iir6	181	13	,	,	,
cord-271972-qhr6iir6	181	14	so	so	IN
cord-271972-qhr6iir6	181	15	as	as	IN
cord-271972-qhr6iir6	181	16	to	to	TO
cord-271972-qhr6iir6	181	17	avoid	avoid	VB
cord-271972-qhr6iir6	181	18	generating	generate	VBG
cord-271972-qhr6iir6	181	19	transcripts	transcript	NNS
cord-271972-qhr6iir6	181	20	where	where	WRB
cord-271972-qhr6iir6	181	21	splicing	splicing	NN
cord-271972-qhr6iir6	181	22	of	of	IN
cord-271972-qhr6iir6	181	23	3	3	CD
cord-271972-qhr6iir6	181	24	genes	gene	NNS
cord-271972-qhr6iir6	181	25	leads	lead	VBZ
cord-271972-qhr6iir6	181	26	to	to	IN
cord-271972-qhr6iir6	181	27	deposition	deposition	NN
cord-271972-qhr6iir6	181	28	of	of	IN
cord-271972-qhr6iir6	181	29	EJCs	ejc	NNS
cord-271972-qhr6iir6	181	30	downstream	downstream	RB
cord-271972-qhr6iir6	181	31	of	of	IN
cord-271972-qhr6iir6	181	32	the	the	DT
cord-271972-qhr6iir6	181	33	termination	termination	NN
cord-271972-qhr6iir6	181	34	codons	codon	NNS
cord-271972-qhr6iir6	181	35	of	of	IN
cord-271972-qhr6iir6	181	36	the	the	DT
cord-271972-qhr6iir6	181	37	5	5	CD
cord-271972-qhr6iir6	181	38	genes	gene	NNS
cord-271972-qhr6iir6	181	39	.	.	.
cord-271972-qhr6iir6	182	1	However	however	RB
cord-271972-qhr6iir6	182	2	,	,	,
cord-271972-qhr6iir6	182	3	a	a	DT
cord-271972-qhr6iir6	182	4	consequence	consequence	NN
cord-271972-qhr6iir6	182	5	of	of	IN
cord-271972-qhr6iir6	182	6	this	this	DT
cord-271972-qhr6iir6	182	7	strategy	strategy	NN
cord-271972-qhr6iir6	182	8	is	be	VBZ
cord-271972-qhr6iir6	182	9	that	that	IN
cord-271972-qhr6iir6	182	10	the	the	DT
cord-271972-qhr6iir6	182	11	5	5	CD
cord-271972-qhr6iir6	182	12	-most	-most	NN
cord-271972-qhr6iir6	182	13	genes	gene	NNS
cord-271972-qhr6iir6	182	14	are	be	VBP
cord-271972-qhr6iir6	182	15	generally	generally	RB
cord-271972-qhr6iir6	182	16	translated	translate	VBN
cord-271972-qhr6iir6	182	17	from	from	IN
cord-271972-qhr6iir6	182	18	completely	completely	RB
cord-271972-qhr6iir6	182	19	unspliced	unspliced	JJ
cord-271972-qhr6iir6	182	20	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	182	21	,	,	,
cord-271972-qhr6iir6	182	22	which	which	WDT
cord-271972-qhr6iir6	182	23	have	have	VBP
cord-271972-qhr6iir6	182	24	very	very	RB
cord-271972-qhr6iir6	182	25	long	long	JJ
cord-271972-qhr6iir6	182	26	UTRs	utr	NNS
cord-271972-qhr6iir6	182	27	between	between	IN
cord-271972-qhr6iir6	182	28	the	the	DT
cord-271972-qhr6iir6	182	29	stop	stop	NN
cord-271972-qhr6iir6	182	30	codon	codon	NN
cord-271972-qhr6iir6	182	31	of	of	IN
cord-271972-qhr6iir6	182	32	the	the	DT
cord-271972-qhr6iir6	182	33	first	first	JJ
cord-271972-qhr6iir6	182	34	gene	gene	NN
cord-271972-qhr6iir6	182	35	and	and	CC
cord-271972-qhr6iir6	182	36	the	the	DT
cord-271972-qhr6iir6	182	37	poly(A	poly(a	JJ
cord-271972-qhr6iir6	182	38	)	)	-RRB-
cord-271972-qhr6iir6	182	39	tail	tail	NN
cord-271972-qhr6iir6	182	40	.	.	.
cord-271972-qhr6iir6	183	1	Thus	thus	RB
cord-271972-qhr6iir6	183	2	,	,	,
cord-271972-qhr6iir6	183	3	some	some	DT
cord-271972-qhr6iir6	183	4	viruses	virus	NNS
cord-271972-qhr6iir6	183	5	specifically	specifically	RB
cord-271972-qhr6iir6	183	6	avoid	avoid	VBP
cord-271972-qhr6iir6	183	7	NMD	NMD	NNP
cord-271972-qhr6iir6	183	8	by	by	IN
cord-271972-qhr6iir6	183	9	encoding	encode	VBG
cord-271972-qhr6iir6	183	10	protective	protective	JJ
cord-271972-qhr6iir6	183	11	elements	element	NNS
cord-271972-qhr6iir6	183	12	within	within	IN
cord-271972-qhr6iir6	183	13	their	-PRON-	PRP$
cord-271972-qhr6iir6	183	14	long	long	JJ
cord-271972-qhr6iir6	183	15	3	3	CD
cord-271972-qhr6iir6	183	16	UTRs	utr	NNS
cord-271972-qhr6iir6	183	17	.	.	.
cord-271972-qhr6iir6	184	1	This	this	DT
cord-271972-qhr6iir6	184	2	is	be	VBZ
cord-271972-qhr6iir6	184	3	best	well	RBS
cord-271972-qhr6iir6	184	4	illustrated	illustrate	VBN
cord-271972-qhr6iir6	184	5	by	by	IN
cord-271972-qhr6iir6	184	6	the	the	DT
cord-271972-qhr6iir6	184	7	avian	avian	JJ
cord-271972-qhr6iir6	184	8	retrovirus	retrovirus	NN
cord-271972-qhr6iir6	184	9	Rous	rous	JJ
cord-271972-qhr6iir6	184	10	sarcoma	sarcoma	NN
cord-271972-qhr6iir6	184	11	virus	virus	NN
cord-271972-qhr6iir6	184	12	(	(	-LRB-
cord-271972-qhr6iir6	184	13	RSV	RSV	NNP
cord-271972-qhr6iir6	184	14	)	)	-RRB-
cord-271972-qhr6iir6	184	15	,	,	,
cord-271972-qhr6iir6	184	16	which	which	WDT
cord-271972-qhr6iir6	184	17	contains	contain	VBZ
cord-271972-qhr6iir6	184	18	a	a	DT
cord-271972-qhr6iir6	184	19	sequence	sequence	NN
cord-271972-qhr6iir6	184	20	element	element	NN
cord-271972-qhr6iir6	184	21	(	(	-LRB-
cord-271972-qhr6iir6	184	22	RSE	RSE	NNP
cord-271972-qhr6iir6	184	23	)	)	-RRB-
cord-271972-qhr6iir6	184	24	downstream	downstream	NN
cord-271972-qhr6iir6	184	25	of	of	IN
cord-271972-qhr6iir6	184	26	the	the	DT
cord-271972-qhr6iir6	184	27	Gag	Gag	NNP
cord-271972-qhr6iir6	184	28	gene	gene	NN
cord-271972-qhr6iir6	184	29	stop	stop	NN
cord-271972-qhr6iir6	184	30	codon	codon	NN
cord-271972-qhr6iir6	184	31	that	that	WDT
cord-271972-qhr6iir6	184	32	prevents	prevent	VBZ
cord-271972-qhr6iir6	184	33	the	the	DT
cord-271972-qhr6iir6	184	34	unspliced	unspliced	JJ
cord-271972-qhr6iir6	184	35	mRNA	mrna	NN
cord-271972-qhr6iir6	184	36	from	from	IN
cord-271972-qhr6iir6	184	37	being	be	VBG
cord-271972-qhr6iir6	184	38	targeted	target	VBN
cord-271972-qhr6iir6	184	39	for	for	IN
cord-271972-qhr6iir6	184	40	degradation	degradation	NN
cord-271972-qhr6iir6	184	41	.	.	.
cord-271972-qhr6iir6	185	1	59	59	CD
cord-271972-qhr6iir6	185	2	Deletion	deletion	NN
cord-271972-qhr6iir6	185	3	of	of	IN
cord-271972-qhr6iir6	185	4	this	this	DT
cord-271972-qhr6iir6	185	5	sequence	sequence	NN
cord-271972-qhr6iir6	185	6	causes	cause	VBZ
cord-271972-qhr6iir6	185	7	a	a	DT
cord-271972-qhr6iir6	185	8	dramatic	dramatic	JJ
cord-271972-qhr6iir6	185	9	shortening	shortening	NN
cord-271972-qhr6iir6	185	10	of	of	IN
cord-271972-qhr6iir6	185	11	the	the	DT
cord-271972-qhr6iir6	185	12	half	half	JJ
cord-271972-qhr6iir6	185	13	-	-	HYPH
cord-271972-qhr6iir6	185	14	life	life	NN
cord-271972-qhr6iir6	185	15	of	of	IN
cord-271972-qhr6iir6	185	16	unspliced	unsplice	VBN
cord-271972-qhr6iir6	186	1	RSV	RSV	NNP
cord-271972-qhr6iir6	186	2	mRNA	mRNA	NNP
cord-271972-qhr6iir6	187	1	in	in	IN
cord-271972-qhr6iir6	187	2	a	a	DT
cord-271972-qhr6iir6	187	3	translation	translation	NN
cord-271972-qhr6iir6	187	4	-	-	:
cord-271972-qhr6iir6	187	5	and	and	CC
cord-271972-qhr6iir6	187	6	Upf1-dependent	upf1-dependent	JJ
cord-271972-qhr6iir6	187	7	manner	manner	NN
cord-271972-qhr6iir6	187	8	,	,	,
cord-271972-qhr6iir6	187	9	whereas	whereas	IN
cord-271972-qhr6iir6	187	10	insertion	insertion	NN
cord-271972-qhr6iir6	187	11	of	of	IN
cord-271972-qhr6iir6	187	12	the	the	DT
cord-271972-qhr6iir6	187	13	RSE	RSE	NNP
cord-271972-qhr6iir6	187	14	protects	protect	VBZ
cord-271972-qhr6iir6	187	15	PTC	PTC	NNP
cord-271972-qhr6iir6	187	16	-	-	HYPH
cord-271972-qhr6iir6	187	17	containing	contain	VBG
cord-271972-qhr6iir6	187	18	NMD	NMD	NNP
cord-271972-qhr6iir6	187	19	substrates	substrate	NNS
cord-271972-qhr6iir6	187	20	from	from	IN
cord-271972-qhr6iir6	187	21	degradation	degradation	NN
cord-271972-qhr6iir6	187	22	.	.	.
cord-271972-qhr6iir6	188	1	Analyses	analysis	NNS
cord-271972-qhr6iir6	188	2	of	of	IN
cord-271972-qhr6iir6	188	3	the	the	DT
cord-271972-qhr6iir6	188	4	RSE	RSE	NNP
cord-271972-qhr6iir6	188	5	structure	structure	NN
cord-271972-qhr6iir6	188	6	using	use	VBG
cord-271972-qhr6iir6	188	7	SHAPE	shape	NN
cord-271972-qhr6iir6	188	8	chemistry	chemistry	NN
cord-271972-qhr6iir6	188	9	and	and	CC
cord-271972-qhr6iir6	188	10	partial	partial	JJ
cord-271972-qhr6iir6	188	11	RNase	rnase	NN
cord-271972-qhr6iir6	188	12	digestion	digestion	NN
cord-271972-qhr6iir6	188	13	indicate	indicate	VBP
cord-271972-qhr6iir6	188	14	the	the	DT
cord-271972-qhr6iir6	188	15	presence	presence	NN
cord-271972-qhr6iir6	188	16	of	of	IN
cord-271972-qhr6iir6	188	17	an	an	DT
cord-271972-qhr6iir6	188	18	AU	AU	NNP
cord-271972-qhr6iir6	188	19	-	-	HYPH
cord-271972-qhr6iir6	188	20	rich	rich	JJ
cord-271972-qhr6iir6	188	21	stretch	stretch	NN
cord-271972-qhr6iir6	188	22	and	and	CC
cord-271972-qhr6iir6	188	23	stem	stem	NN
cord-271972-qhr6iir6	188	24	-	-	HYPH
cord-271972-qhr6iir6	188	25	loop	loop	NN
cord-271972-qhr6iir6	188	26	elements	element	NNS
cord-271972-qhr6iir6	188	27	that	that	WDT
cord-271972-qhr6iir6	188	28	are	be	VBP
cord-271972-qhr6iir6	188	29	conserved	conserve	VBN
cord-271972-qhr6iir6	188	30	amongst	amongst	IN
cord-271972-qhr6iir6	188	31	20	20	CD
cord-271972-qhr6iir6	188	32	different	different	JJ
cord-271972-qhr6iir6	188	33	avian	avian	JJ
cord-271972-qhr6iir6	188	34	retroviruses	retrovirus	NNS
cord-271972-qhr6iir6	188	35	.	.	.
cord-271972-qhr6iir6	189	1	60	60	CD
cord-271972-qhr6iir6	190	1	While	while	IN
cord-271972-qhr6iir6	190	2	the	the	DT
cord-271972-qhr6iir6	190	3	mechanisms	mechanism	NNS
cord-271972-qhr6iir6	190	4	by	by	IN
cord-271972-qhr6iir6	190	5	which	which	WDT
cord-271972-qhr6iir6	190	6	the	the	DT
cord-271972-qhr6iir6	190	7	RSE	RSE	NNP
cord-271972-qhr6iir6	190	8	blocks	block	VBZ
cord-271972-qhr6iir6	190	9	NMD	NMD	NNP
cord-271972-qhr6iir6	190	10	remain	remain	VBP
cord-271972-qhr6iir6	190	11	unknown	unknown	JJ
cord-271972-qhr6iir6	190	12	,	,	,
cord-271972-qhr6iir6	190	13	an	an	DT
cord-271972-qhr6iir6	190	14	intriguing	intriguing	JJ
cord-271972-qhr6iir6	190	15	preliminary	preliminary	JJ
cord-271972-qhr6iir6	190	16	observation	observation	NN
cord-271972-qhr6iir6	190	17	suggests	suggest	VBZ
cord-271972-qhr6iir6	190	18	that	that	IN
cord-271972-qhr6iir6	190	19	it	-PRON-	PRP
cord-271972-qhr6iir6	190	20	may	may	MD
cord-271972-qhr6iir6	190	21	form	form	VB
cord-271972-qhr6iir6	190	22	an	an	DT
cord-271972-qhr6iir6	190	23	RNA	RNA	NNP
cord-271972-qhr6iir6	190	24	-	-	HYPH
cord-271972-qhr6iir6	190	25	RNA	RNA	NNP
cord-271972-qhr6iir6	190	26	interaction	interaction	NN
cord-271972-qhr6iir6	190	27	with	with	IN
cord-271972-qhr6iir6	190	28	a	a	DT
cord-271972-qhr6iir6	190	29	region	region	NN
cord-271972-qhr6iir6	190	30	just	just	RB
cord-271972-qhr6iir6	190	31	upstream	upstream	RB
cord-271972-qhr6iir6	190	32	of	of	IN
cord-271972-qhr6iir6	190	33	the	the	DT
cord-271972-qhr6iir6	190	34	RSV	RSV	NNP
cord-271972-qhr6iir6	190	35	poly(A	poly(A	NNP
cord-271972-qhr6iir6	190	36	)	)	-RRB-
cord-271972-qhr6iir6	190	37	site	site	NN
cord-271972-qhr6iir6	190	38	.	.	.
cord-271972-qhr6iir6	191	1	60	60	CD
cord-271972-qhr6iir6	192	1	Given	give	VBN
cord-271972-qhr6iir6	192	2	the	the	DT
cord-271972-qhr6iir6	192	3	correlation	correlation	NN
cord-271972-qhr6iir6	192	4	between	between	IN
cord-271972-qhr6iir6	192	5	the	the	DT
cord-271972-qhr6iir6	192	6	proximity	proximity	NN
cord-271972-qhr6iir6	192	7	of	of	IN
cord-271972-qhr6iir6	192	8	the	the	DT
cord-271972-qhr6iir6	192	9	stop	stop	NN
cord-271972-qhr6iir6	192	10	codon	codon	NN
cord-271972-qhr6iir6	192	11	and	and	CC
cord-271972-qhr6iir6	192	12	poly(A	poly(a	JJ
cord-271972-qhr6iir6	192	13	)	)	-RRB-
cord-271972-qhr6iir6	192	14	tail	tail	NN
cord-271972-qhr6iir6	192	15	for	for	IN
cord-271972-qhr6iir6	192	16	NMD	NMD	NNP
cord-271972-qhr6iir6	192	17	activation	activation	NN
cord-271972-qhr6iir6	192	18	,	,	,
cord-271972-qhr6iir6	192	19	such	such	PDT
cord-271972-qhr6iir6	192	20	an	an	DT
cord-271972-qhr6iir6	192	21	interaction	interaction	NN
cord-271972-qhr6iir6	192	22	could	could	MD
cord-271972-qhr6iir6	192	23	facilitate	facilitate	VB
cord-271972-qhr6iir6	192	24	translation	translation	NN
cord-271972-qhr6iir6	192	25	termination	termination	NN
cord-271972-qhr6iir6	192	26	by	by	IN
cord-271972-qhr6iir6	192	27	bringing	bring	VBG
cord-271972-qhr6iir6	192	28	the	the	DT
cord-271972-qhr6iir6	192	29	poly(A	poly(a	JJ
cord-271972-qhr6iir6	192	30	)	)	-RRB-
cord-271972-qhr6iir6	192	31	tail	tail	NN
cord-271972-qhr6iir6	192	32	closer	close	RBR
cord-271972-qhr6iir6	192	33	to	to	IN
cord-271972-qhr6iir6	192	34	the	the	DT
cord-271972-qhr6iir6	192	35	Gag	Gag	NNP
cord-271972-qhr6iir6	192	36	stop	stop	NN
cord-271972-qhr6iir6	192	37	codon	codon	NN
cord-271972-qhr6iir6	192	38	,	,	,
cord-271972-qhr6iir6	192	39	thereby	thereby	RB
cord-271972-qhr6iir6	192	40	decreasing	decrease	VBG
cord-271972-qhr6iir6	192	41	Upf1	upf1	JJ
cord-271972-qhr6iir6	192	42	recruitment	recruitment	NN
cord-271972-qhr6iir6	192	43	(	(	-LRB-
cord-271972-qhr6iir6	192	44	Figure	figure	NN
cord-271972-qhr6iir6	192	45	4	4	CD
cord-271972-qhr6iir6	192	46	)	)	-RRB-
cord-271972-qhr6iir6	192	47	.	.	.
cord-271972-qhr6iir6	193	1	Alternatively	alternatively	RB
cord-271972-qhr6iir6	193	2	,	,	,
cord-271972-qhr6iir6	193	3	the	the	DT
cord-271972-qhr6iir6	193	4	RSE	RSE	NNP
cord-271972-qhr6iir6	193	5	may	may	MD
cord-271972-qhr6iir6	193	6	bind	bind	VB
cord-271972-qhr6iir6	193	7	proteins	protein	NNS
cord-271972-qhr6iir6	193	8	that	that	WDT
cord-271972-qhr6iir6	193	9	influence	influence	VBP
cord-271972-qhr6iir6	193	10	the	the	DT
cord-271972-qhr6iir6	193	11	stability	stability	NN
cord-271972-qhr6iir6	193	12	of	of	IN
cord-271972-qhr6iir6	193	13	the	the	DT
cord-271972-qhr6iir6	193	14	mRNA	mrna	NN
cord-271972-qhr6iir6	193	15	.	.	.
cord-271972-qhr6iir6	194	1	It	-PRON-	PRP
cord-271972-qhr6iir6	194	2	will	will	MD
cord-271972-qhr6iir6	194	3	be	be	VB
cord-271972-qhr6iir6	194	4	of	of	IN
cord-271972-qhr6iir6	194	5	interest	interest	NN
cord-271972-qhr6iir6	194	6	to	to	TO
cord-271972-qhr6iir6	194	7	examine	examine	VB
cord-271972-qhr6iir6	194	8	whether	whether	IN
cord-271972-qhr6iir6	194	9	similar	similar	JJ
cord-271972-qhr6iir6	194	10	,	,	,
cord-271972-qhr6iir6	194	11	perhaps	perhaps	RB
cord-271972-qhr6iir6	194	12	structurally	structurally	RB
cord-271972-qhr6iir6	194	13	related	related	JJ
cord-271972-qhr6iir6	194	14	elements	element	NNS
cord-271972-qhr6iir6	194	15	exist	exist	VBP
cord-271972-qhr6iir6	194	16	within	within	IN
cord-271972-qhr6iir6	194	17	other	other	JJ
cord-271972-qhr6iir6	194	18	viral	viral	JJ
cord-271972-qhr6iir6	194	19	or	or	CC
cord-271972-qhr6iir6	194	20	cellular	cellular	JJ
cord-271972-qhr6iir6	194	21	mRNAs	mrna	NNS
cord-271972-qhr6iir6	194	22	with	with	IN
cord-271972-qhr6iir6	194	23	unusually	unusually	RB
cord-271972-qhr6iir6	194	24	long	long	JJ
cord-271972-qhr6iir6	194	25	3	3	CD
cord-271972-qhr6iir6	194	26	UTRs	utr	NNS
cord-271972-qhr6iir6	194	27	,	,	,
cord-271972-qhr6iir6	194	28	as	as	IN
cord-271972-qhr6iir6	194	29	this	this	DT
cord-271972-qhr6iir6	194	30	may	may	MD
cord-271972-qhr6iir6	194	31	shed	shed	VB
cord-271972-qhr6iir6	194	32	light	light	NN
cord-271972-qhr6iir6	194	33	on	on	IN
cord-271972-qhr6iir6	194	34	how	how	WRB
cord-271972-qhr6iir6	194	35	this	this	DT
cord-271972-qhr6iir6	194	36	important	important	JJ
cord-271972-qhr6iir6	194	37	pathway	pathway	NN
cord-271972-qhr6iir6	194	38	is	be	VBZ
cord-271972-qhr6iir6	194	39	regulated	regulate	VBN
cord-271972-qhr6iir6	194	40	normally	normally	RB
cord-271972-qhr6iir6	194	41	in	in	IN
cord-271972-qhr6iir6	194	42	cells	cell	NNS
cord-271972-qhr6iir6	194	43	and	and	CC
cord-271972-qhr6iir6	194	44	in	in	IN
cord-271972-qhr6iir6	194	45	response	response	NN
cord-271972-qhr6iir6	194	46	to	to	IN
cord-271972-qhr6iir6	194	47	infection	infection	NN
cord-271972-qhr6iir6	194	48	.	.	.
cord-271972-qhr6iir6	195	1	For	for	IN
cord-271972-qhr6iir6	195	2	example	example	NN
cord-271972-qhr6iir6	195	3	,	,	,
cord-271972-qhr6iir6	195	4	both	both	DT
cord-271972-qhr6iir6	195	5	coronavirus	coronavirus	NN
cord-271972-qhr6iir6	195	6	and	and	CC
cord-271972-qhr6iir6	195	7	SINV	SINV	NNP
cord-271972-qhr6iir6	195	8	have	have	VBP
cord-271972-qhr6iir6	195	9	long	long	JJ
cord-271972-qhr6iir6	195	10	stretches	stretch	NNS
cord-271972-qhr6iir6	195	11	of	of	IN
cord-271972-qhr6iir6	195	12	coding	code	VBG
cord-271972-qhr6iir6	195	13	sequence	sequence	NN
cord-271972-qhr6iir6	195	14	at	at	IN
cord-271972-qhr6iir6	195	15	their	-PRON-	PRP$
cord-271972-qhr6iir6	195	16	3	3	CD
cord-271972-qhr6iir6	195	17	end	end	NN
cord-271972-qhr6iir6	195	18	that	that	WDT
cord-271972-qhr6iir6	195	19	are	be	VBP
cord-271972-qhr6iir6	195	20	not	not	RB
cord-271972-qhr6iir6	195	21	translated	translate	VBN
cord-271972-qhr6iir6	195	22	from	from	IN
cord-271972-qhr6iir6	195	23	the	the	DT
cord-271972-qhr6iir6	195	24	genomic	genomic	JJ
cord-271972-qhr6iir6	195	25	mRNA	mrna	NN
cord-271972-qhr6iir6	195	26	,	,	,
cord-271972-qhr6iir6	195	27	but	but	CC
cord-271972-qhr6iir6	195	28	instead	instead	RB
cord-271972-qhr6iir6	195	29	are	be	VBP
cord-271972-qhr6iir6	195	30	expressed	express	VBN
cord-271972-qhr6iir6	195	31	from	from	IN
cord-271972-qhr6iir6	195	32	subgenomic	subgenomic	NNP
cord-271972-qhr6iir6	195	33	transcripts	transcript	NNS
cord-271972-qhr6iir6	195	34	.	.	.
cord-271972-qhr6iir6	196	1	61	61	CD
cord-271972-qhr6iir6	196	2	,	,	,
cord-271972-qhr6iir6	196	3	62	62	CD
cord-271972-qhr6iir6	197	1	During	during	IN
cord-271972-qhr6iir6	197	2	the	the	DT
cord-271972-qhr6iir6	197	3	translation	translation	NN
cord-271972-qhr6iir6	197	4	of	of	IN
cord-271972-qhr6iir6	197	5	genes	gene	NNS
cord-271972-qhr6iir6	197	6	at	at	IN
cord-271972-qhr6iir6	197	7	the	the	DT
cord-271972-qhr6iir6	197	8	5	5	CD
cord-271972-qhr6iir6	197	9	end	end	NN
cord-271972-qhr6iir6	197	10	of	of	IN
cord-271972-qhr6iir6	197	11	these	these	DT
cord-271972-qhr6iir6	197	12	viral	viral	JJ
cord-271972-qhr6iir6	197	13	genomes	genome	NNS
cord-271972-qhr6iir6	197	14	such	such	JJ
cord-271972-qhr6iir6	197	15	sequences	sequence	NNS
cord-271972-qhr6iir6	197	16	would	would	MD
cord-271972-qhr6iir6	197	17	appear	appear	VB
cord-271972-qhr6iir6	197	18	as	as	RB
cord-271972-qhr6iir6	197	19	very	very	RB
cord-271972-qhr6iir6	197	20	long	long	JJ
cord-271972-qhr6iir6	197	21	3	3	CD
cord-271972-qhr6iir6	197	22	UTRs	utr	NNS
cord-271972-qhr6iir6	197	23	,	,	,
cord-271972-qhr6iir6	197	24	which	which	WDT
cord-271972-qhr6iir6	197	25	might	may	MD
cord-271972-qhr6iir6	197	26	be	be	VB
cord-271972-qhr6iir6	197	27	predicted	predict	VBN
cord-271972-qhr6iir6	197	28	to	to	TO
cord-271972-qhr6iir6	197	29	trigger	trigger	VB
cord-271972-qhr6iir6	197	30	NMD	NMD	NNP
cord-271972-qhr6iir6	197	31	even	even	RB
cord-271972-qhr6iir6	197	32	in	in	IN
cord-271972-qhr6iir6	197	33	the	the	DT
cord-271972-qhr6iir6	197	34	absence	absence	NN
cord-271972-qhr6iir6	197	35	of	of	IN
cord-271972-qhr6iir6	197	36	nuclear	nuclear	JJ
cord-271972-qhr6iir6	197	37	splicing	splicing	NN
cord-271972-qhr6iir6	197	38	and	and	CC
cord-271972-qhr6iir6	197	39	EJC	EJC	NNP
cord-271972-qhr6iir6	197	40	deposition	deposition	NN
cord-271972-qhr6iir6	197	41	.	.	.
cord-271972-qhr6iir6	198	1	Thus	thus	RB
cord-271972-qhr6iir6	198	2	,	,	,
cord-271972-qhr6iir6	198	3	a	a	DT
cord-271972-qhr6iir6	198	4	protective	protective	JJ
cord-271972-qhr6iir6	198	5	mechanism	mechanism	NN
cord-271972-qhr6iir6	198	6	may	may	MD
cord-271972-qhr6iir6	198	7	be	be	VB
cord-271972-qhr6iir6	198	8	required	require	VBN
cord-271972-qhr6iir6	198	9	to	to	TO
cord-271972-qhr6iir6	198	10	actively	actively	RB
cord-271972-qhr6iir6	198	11	stabilize	stabilize	VB
cord-271972-qhr6iir6	198	12	the	the	DT
cord-271972-qhr6iir6	198	13	RNA	RNA	NNP
cord-271972-qhr6iir6	198	14	genomes	genome	NNS
cord-271972-qhr6iir6	198	15	in	in	IN
cord-271972-qhr6iir6	198	16	such	such	JJ
cord-271972-qhr6iir6	198	17	cases	case	NNS
cord-271972-qhr6iir6	198	18	.	.	.
cord-271972-qhr6iir6	199	1	A	a	DT
cord-271972-qhr6iir6	199	2	similar	similar	JJ
cord-271972-qhr6iir6	199	3	situation	situation	NN
cord-271972-qhr6iir6	199	4	could	could	MD
cord-271972-qhr6iir6	199	5	arise	arise	VB
cord-271972-qhr6iir6	199	6	during	during	IN
cord-271972-qhr6iir6	199	7	infection	infection	NN
cord-271972-qhr6iir6	199	8	with	with	IN
cord-271972-qhr6iir6	199	9	some	some	DT
cord-271972-qhr6iir6	199	10	DNA	dna	NN
cord-271972-qhr6iir6	199	11	viruses	virus	NNS
cord-271972-qhr6iir6	199	12	such	such	JJ
cord-271972-qhr6iir6	199	13	as	as	IN
cord-271972-qhr6iir6	199	14	those	those	DT
cord-271972-qhr6iir6	199	15	of	of	IN
cord-271972-qhr6iir6	199	16	the	the	DT
cord-271972-qhr6iir6	199	17	gamma	gamma	NN
cord-271972-qhr6iir6	199	18	-	-	HYPH
cord-271972-qhr6iir6	199	19	herpesvirus	herpesvirus	NN
cord-271972-qhr6iir6	199	20	subfamily	subfamily	NN
cord-271972-qhr6iir6	199	21	,	,	,
cord-271972-qhr6iir6	199	22	which	which	WDT
cord-271972-qhr6iir6	199	23	transcribe	transcribe	VBP
cord-271972-qhr6iir6	199	24	a	a	DT
cord-271972-qhr6iir6	199	25	number	number	NN
cord-271972-qhr6iir6	199	26	of	of	IN
cord-271972-qhr6iir6	199	27	potentially	potentially	RB
cord-271972-qhr6iir6	199	28	polycistronic	polycistronic	JJ
cord-271972-qhr6iir6	199	29	messages	message	NNS
cord-271972-qhr6iir6	199	30	.	.	.
cord-271972-qhr6iir6	200	1	63	63	CD
cord-271972-qhr6iir6	200	2	Additional	Additional	NNP
cord-271972-qhr6iir6	200	3	,	,	,
cord-271972-qhr6iir6	200	4	NMD	NMD	NNP
cord-271972-qhr6iir6	200	5	-	-	HYPH
cord-271972-qhr6iir6	200	6	independent	independent	JJ
cord-271972-qhr6iir6	200	7	roles	role	NNS
cord-271972-qhr6iir6	200	8	in	in	IN
cord-271972-qhr6iir6	200	9	viral	viral	JJ
cord-271972-qhr6iir6	200	10	infection	infection	NN
cord-271972-qhr6iir6	200	11	have	have	VBP
cord-271972-qhr6iir6	200	12	been	be	VBN
cord-271972-qhr6iir6	200	13	proposed	propose	VBN
cord-271972-qhr6iir6	200	14	for	for	IN
cord-271972-qhr6iir6	200	15	Upf1	Upf1	NNP
cord-271972-qhr6iir6	200	16	.	.	.
cord-271972-qhr6iir6	201	1	For	for	IN
cord-271972-qhr6iir6	201	2	example	example	NN
cord-271972-qhr6iir6	201	3	,	,	,
cord-271972-qhr6iir6	201	4	Upf1	Upf1	NNP
cord-271972-qhr6iir6	201	5	associates	associate	NNS
cord-271972-qhr6iir6	201	6	with	with	IN
cord-271972-qhr6iir6	201	7	HIV-1	HIV-1	NNP
cord-271972-qhr6iir6	201	8	RNA	RNA	NNP
cord-271972-qhr6iir6	201	9	,	,	,
cord-271972-qhr6iir6	201	10	and	and	CC
cord-271972-qhr6iir6	201	11	its	-PRON-	PRP$
cord-271972-qhr6iir6	201	12	presence	presence	NN
cord-271972-qhr6iir6	201	13	stabilizes	stabilize	VBZ
cord-271972-qhr6iir6	201	14	the	the	DT
cord-271972-qhr6iir6	201	15	viral	viral	JJ
cord-271972-qhr6iir6	201	16	genome	genome	NN
cord-271972-qhr6iir6	201	17	and	and	CC
cord-271972-qhr6iir6	201	18	facilitates	facilitate	VBZ
cord-271972-qhr6iir6	201	19	translation	translation	NN
cord-271972-qhr6iir6	201	20	of	of	IN
cord-271972-qhr6iir6	201	21	the	the	DT
cord-271972-qhr6iir6	201	22	Gag	Gag	NNP
cord-271972-qhr6iir6	201	23	precursor	precursor	NN
cord-271972-qhr6iir6	201	24	.	.	.
cord-271972-qhr6iir6	202	1	64	64	CD
cord-271972-qhr6iir6	203	1	These	these	DT
cord-271972-qhr6iir6	203	2	functions	function	NNS
cord-271972-qhr6iir6	203	3	of	of	IN
cord-271972-qhr6iir6	203	4	Upf1	Upf1	NNP
cord-271972-qhr6iir6	203	5	are	be	VBP
cord-271972-qhr6iir6	203	6	genetically	genetically	RB
cord-271972-qhr6iir6	203	7	separable	separable	JJ
cord-271972-qhr6iir6	203	8	from	from	IN
cord-271972-qhr6iir6	203	9	its	-PRON-	PRP$
cord-271972-qhr6iir6	203	10	role	role	NN
cord-271972-qhr6iir6	203	11	in	in	IN
cord-271972-qhr6iir6	203	12	NMD	NMD	NNP
cord-271972-qhr6iir6	203	13	,	,	,
cord-271972-qhr6iir6	203	14	as	as	IN
cord-271972-qhr6iir6	203	15	they	-PRON-	PRP
cord-271972-qhr6iir6	203	16	are	be	VBP
cord-271972-qhr6iir6	203	17	observed	observe	VBN
cord-271972-qhr6iir6	203	18	even	even	RB
cord-271972-qhr6iir6	203	19	with	with	IN
cord-271972-qhr6iir6	203	20	mutants	mutant	NNS
cord-271972-qhr6iir6	203	21	of	of	IN
cord-271972-qhr6iir6	203	22	the	the	DT
cord-271972-qhr6iir6	203	23	Upf1	Upf1	NNP
cord-271972-qhr6iir6	203	24	RNA	RNA	NNP
cord-271972-qhr6iir6	203	25	helicase	helicase	NN
cord-271972-qhr6iir6	203	26	domain	domain	NN
cord-271972-qhr6iir6	203	27	that	that	WDT
cord-271972-qhr6iir6	203	28	have	have	VBP
cord-271972-qhr6iir6	203	29	dominant	dominant	JJ
cord-271972-qhr6iir6	203	30	-	-	HYPH
cord-271972-qhr6iir6	203	31	negative	negative	JJ
cord-271972-qhr6iir6	203	32	effects	effect	NNS
cord-271972-qhr6iir6	203	33	on	on	IN
cord-271972-qhr6iir6	203	34	NMD	NMD	NNP
cord-271972-qhr6iir6	203	35	.	.	.
cord-271972-qhr6iir6	204	1	An	an	DT
cord-271972-qhr6iir6	204	2	intriguing	intriguing	JJ
cord-271972-qhr6iir6	204	3	idea	idea	NN
cord-271972-qhr6iir6	204	4	is	be	VBZ
cord-271972-qhr6iir6	204	5	that	that	IN
cord-271972-qhr6iir6	204	6	cells	cell	NNS
cord-271972-qhr6iir6	204	7	may	may	MD
cord-271972-qhr6iir6	204	8	specifically	specifically	RB
cord-271972-qhr6iir6	204	9	transform	transform	VB
cord-271972-qhr6iir6	204	10	viral	viral	JJ
cord-271972-qhr6iir6	204	11	mRNAs	mrnas	TO
cord-271972-qhr6iir6	204	12	into	into	IN
cord-271972-qhr6iir6	204	13	targets	target	NNS
cord-271972-qhr6iir6	204	14	of	of	IN
cord-271972-qhr6iir6	204	15	quality	quality	NN
cord-271972-qhr6iir6	204	16	control	control	NN
cord-271972-qhr6iir6	204	17	pathways	pathway	NNS
cord-271972-qhr6iir6	204	18	as	as	IN
cord-271972-qhr6iir6	204	19	an	an	DT
cord-271972-qhr6iir6	204	20	antiviral	antiviral	JJ
cord-271972-qhr6iir6	204	21	measure	measure	NN
cord-271972-qhr6iir6	204	22	.	.	.
cord-271972-qhr6iir6	205	1	Evidence	evidence	NN
cord-271972-qhr6iir6	205	2	for	for	IN
cord-271972-qhr6iir6	205	3	this	this	DT
cord-271972-qhr6iir6	205	4	comes	come	VBZ
cord-271972-qhr6iir6	205	5	from	from	IN
cord-271972-qhr6iir6	205	6	studies	study	NNS
cord-271972-qhr6iir6	205	7	with	with	IN
cord-271972-qhr6iir6	205	8	the	the	DT
cord-271972-qhr6iir6	205	9	pokeweed	pokeweed	JJ
cord-271972-qhr6iir6	205	10	antiviral	antiviral	JJ
cord-271972-qhr6iir6	205	11	protein	protein	NN
cord-271972-qhr6iir6	205	12	(	(	-LRB-
cord-271972-qhr6iir6	205	13	PAP	PAP	NNP
cord-271972-qhr6iir6	205	14	)	)	-RRB-
cord-271972-qhr6iir6	205	15	,	,	,
cord-271972-qhr6iir6	205	16	a	a	DT
cord-271972-qhr6iir6	205	17	ribosome	ribosome	NN
cord-271972-qhr6iir6	205	18	-	-	HYPH
cord-271972-qhr6iir6	205	19	inactivating	inactivate	VBG
cord-271972-qhr6iir6	205	20	factor	factor	NN
cord-271972-qhr6iir6	205	21	isolated	isolate	VBN
cord-271972-qhr6iir6	205	22	from	from	IN
cord-271972-qhr6iir6	205	23	the	the	DT
cord-271972-qhr6iir6	205	24	pokeweed	pokeweed	JJ
cord-271972-qhr6iir6	205	25	plant	plant	NN
cord-271972-qhr6iir6	205	26	Phytolacca	Phytolacca	NNP
cord-271972-qhr6iir6	205	27	americana	americana	NNP
cord-271972-qhr6iir6	205	28	that	that	WDT
cord-271972-qhr6iir6	205	29	functions	function	VBZ
cord-271972-qhr6iir6	205	30	via	via	IN
cord-271972-qhr6iir6	205	31	RNA	RNA	NNP
cord-271972-qhr6iir6	205	32	depurination	depurination	NN
cord-271972-qhr6iir6	205	33	.	.	.
cord-271972-qhr6iir6	206	1	[	[	-LRB-
cord-271972-qhr6iir6	206	2	65	65	CD
cord-271972-qhr6iir6	206	3	]	]	-RRB-
cord-271972-qhr6iir6	206	4	[	[	-LRB-
cord-271972-qhr6iir6	206	5	66	66	CD
cord-271972-qhr6iir6	206	6	]	]	-RRB-
cord-271972-qhr6iir6	207	1	[	[	-LRB-
cord-271972-qhr6iir6	207	2	67	67	CD
cord-271972-qhr6iir6	207	3	]	]	-RRB-
cord-271972-qhr6iir6	208	1	This	this	DT
cord-271972-qhr6iir6	208	2	protein	protein	NN
cord-271972-qhr6iir6	208	3	has	have	VBZ
cord-271972-qhr6iir6	208	4	a	a	DT
cord-271972-qhr6iir6	208	5	broad	broad	JJ
cord-271972-qhr6iir6	208	6	-	-	HYPH
cord-271972-qhr6iir6	208	7	spectrum	spectrum	NN
cord-271972-qhr6iir6	208	8	antiviral	antiviral	JJ
cord-271972-qhr6iir6	208	9	activity	activity	NN
cord-271972-qhr6iir6	208	10	against	against	IN
cord-271972-qhr6iir6	208	11	both	both	DT
cord-271972-qhr6iir6	208	12	plant	plant	NN
cord-271972-qhr6iir6	208	13	and	and	CC
cord-271972-qhr6iir6	208	14	animal	animal	NN
cord-271972-qhr6iir6	208	15	viruses	virus	NNS
cord-271972-qhr6iir6	208	16	,	,	,
cord-271972-qhr6iir6	208	17	including	include	VBG
cord-271972-qhr6iir6	208	18	HIV	HIV	NNP
cord-271972-qhr6iir6	208	19	,	,	,
cord-271972-qhr6iir6	208	20	68	68	CD
cord-271972-qhr6iir6	208	21	and	and	CC
cord-271972-qhr6iir6	208	22	has	have	VBZ
cord-271972-qhr6iir6	208	23	generated	generate	VBN
cord-271972-qhr6iir6	208	24	interest	interest	NN
cord-271972-qhr6iir6	208	25	as	as	IN
cord-271972-qhr6iir6	208	26	a	a	DT
cord-271972-qhr6iir6	208	27	potential	potential	JJ
cord-271972-qhr6iir6	208	28	antiviral	antiviral	JJ
cord-271972-qhr6iir6	208	29	treatment	treatment	NN
cord-271972-qhr6iir6	208	30	.	.	.
cord-271972-qhr6iir6	209	1	69	69	CD
cord-271972-qhr6iir6	210	1	Although	although	IN
cord-271972-qhr6iir6	210	2	initially	initially	RB
cord-271972-qhr6iir6	210	3	antiviral	antiviral	JJ
cord-271972-qhr6iir6	210	4	activity	activity	NN
cord-271972-qhr6iir6	210	5	was	be	VBD
cord-271972-qhr6iir6	210	6	ascribed	ascribe	VBN
cord-271972-qhr6iir6	210	7	to	to	IN
cord-271972-qhr6iir6	210	8	the	the	DT
cord-271972-qhr6iir6	210	9	ribosome	ribosome	NN
cord-271972-qhr6iir6	210	10	-	-	HYPH
cord-271972-qhr6iir6	210	11	inactivating	inactivate	VBG
cord-271972-qhr6iir6	210	12	function	function	NN
cord-271972-qhr6iir6	210	13	of	of	IN
cord-271972-qhr6iir6	210	14	PAP	pap	NN
cord-271972-qhr6iir6	210	15	,	,	,
cord-271972-qhr6iir6	210	16	it	-PRON-	PRP
cord-271972-qhr6iir6	210	17	was	be	VBD
cord-271972-qhr6iir6	210	18	subsequently	subsequently	RB
cord-271972-qhr6iir6	210	19	found	find	VBN
cord-271972-qhr6iir6	210	20	that	that	IN
cord-271972-qhr6iir6	210	21	some	some	DT
cord-271972-qhr6iir6	210	22	of	of	IN
cord-271972-qhr6iir6	210	23	the	the	DT
cord-271972-qhr6iir6	210	24	PAP	pap	NN
cord-271972-qhr6iir6	210	25	mutants	mutant	NNS
cord-271972-qhr6iir6	210	26	that	that	WDT
cord-271972-qhr6iir6	210	27	are	be	VBP
cord-271972-qhr6iir6	210	28	unable	unable	JJ
cord-271972-qhr6iir6	210	29	to	to	TO
cord-271972-qhr6iir6	210	30	depurinate	depurinate	NNP
cord-271972-qhr6iir6	210	31	ribosomal	ribosomal	NNP
cord-271972-qhr6iir6	210	32	RNA	RNA	NNP
cord-271972-qhr6iir6	210	33	(	(	-LRB-
cord-271972-qhr6iir6	210	34	rRNA	rRNA	NNP
cord-271972-qhr6iir6	210	35	)	)	-RRB-
cord-271972-qhr6iir6	210	36	can	can	MD
cord-271972-qhr6iir6	210	37	still	still	RB
cord-271972-qhr6iir6	210	38	selectively	selectively	RB
cord-271972-qhr6iir6	210	39	inhibit	inhibit	VB
cord-271972-qhr6iir6	210	40	viral	viral	JJ
cord-271972-qhr6iir6	210	41	replication	replication	NN
cord-271972-qhr6iir6	210	42	.	.	.
cord-271972-qhr6iir6	211	1	70	70	CD
cord-271972-qhr6iir6	211	2	PAP	pap	NN
cord-271972-qhr6iir6	211	3	was	be	VBD
cord-271972-qhr6iir6	211	4	subsequently	subsequently	RB
cord-271972-qhr6iir6	211	5	shown	show	VBN
cord-271972-qhr6iir6	211	6	to	to	IN
cord-271972-qhr6iir6	211	7	depurinate	depurinate	NNP
cord-271972-qhr6iir6	211	8	capped	cap	VBN
cord-271972-qhr6iir6	211	9	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	211	10	,	,	,
cord-271972-qhr6iir6	211	11	and	and	CC
cord-271972-qhr6iir6	211	12	the	the	DT
cord-271972-qhr6iir6	211	13	aforementioned	aforementioned	JJ
cord-271972-qhr6iir6	211	14	mutants	mutant	NNS
cord-271972-qhr6iir6	211	15	were	be	VBD
cord-271972-qhr6iir6	211	16	shown	show	VBN
cord-271972-qhr6iir6	211	17	to	to	TO
cord-271972-qhr6iir6	211	18	retain	retain	VB
cord-271972-qhr6iir6	211	19	the	the	DT
cord-271972-qhr6iir6	211	20	ability	ability	NN
cord-271972-qhr6iir6	211	21	to	to	TO
cord-271972-qhr6iir6	211	22	depurinate	depurinate	VB
cord-271972-qhr6iir6	211	23	mRNAs	mrnas	CD
cord-271972-qhr6iir6	211	24	.	.	.
cord-271972-qhr6iir6	212	1	66	66	CD
cord-271972-qhr6iir6	213	1	Recent	recent	JJ
cord-271972-qhr6iir6	213	2	studies	study	NNS
cord-271972-qhr6iir6	213	3	in	in	IN
cord-271972-qhr6iir6	213	4	yeast	yeast	NN
cord-271972-qhr6iir6	213	5	using	use	VBG
cord-271972-qhr6iir6	213	6	BMV	BMV	NNP
cord-271972-qhr6iir6	213	7	have	have	VBP
cord-271972-qhr6iir6	213	8	shown	show	VBN
cord-271972-qhr6iir6	213	9	that	that	IN
cord-271972-qhr6iir6	213	10	BMV	BMV	NNP
cord-271972-qhr6iir6	213	11	RNAs	rna	NNS
cord-271972-qhr6iir6	213	12	become	become	VBP
cord-271972-qhr6iir6	213	13	depurinated	depurinate	VBN
cord-271972-qhr6iir6	213	14	upon	upon	IN
cord-271972-qhr6iir6	213	15	PAP	pap	NN
cord-271972-qhr6iir6	213	16	expression	expression	NN
cord-271972-qhr6iir6	213	17	,	,	,
cord-271972-qhr6iir6	213	18	leading	lead	VBG
cord-271972-qhr6iir6	213	19	to	to	IN
cord-271972-qhr6iir6	213	20	ribosome	ribosome	NN
cord-271972-qhr6iir6	213	21	stalling	stalling	NN
cord-271972-qhr6iir6	213	22	and	and	CC
cord-271972-qhr6iir6	213	23	enhanced	enhance	VBN
cord-271972-qhr6iir6	213	24	RNA	RNA	NNP
cord-271972-qhr6iir6	213	25	turnover	turnover	NN
cord-271972-qhr6iir6	213	26	71	71	CD
cord-271972-qhr6iir6	214	1	(	(	-LRB-
cord-271972-qhr6iir6	214	2	Figure	figure	NN
cord-271972-qhr6iir6	214	3	5	5	CD
cord-271972-qhr6iir6	214	4	)	)	-RRB-
cord-271972-qhr6iir6	214	5	.	.	.
cord-271972-qhr6iir6	215	1	Interestingly	interestingly	RB
cord-271972-qhr6iir6	215	2	,	,	,
cord-271972-qhr6iir6	215	3	PAP	pap	NN
cord-271972-qhr6iir6	215	4	-	-	HYPH
cord-271972-qhr6iir6	215	5	induced	induce	VBN
cord-271972-qhr6iir6	215	6	turnover	turnover	NN
cord-271972-qhr6iir6	215	7	of	of	IN
cord-271972-qhr6iir6	215	8	BMV	BMV	NNP
cord-271972-qhr6iir6	215	9	RNA	RNA	NNP
cord-271972-qhr6iir6	215	10	did	do	VBD
cord-271972-qhr6iir6	215	11	not	not	RB
cord-271972-qhr6iir6	215	12	occur	occur	VB
cord-271972-qhr6iir6	215	13	in	in	IN
cord-271972-qhr6iir6	215	14	yeast	yeast	NN
cord-271972-qhr6iir6	215	15	defective	defective	JJ
cord-271972-qhr6iir6	215	16	in	in	IN
cord-271972-qhr6iir6	215	17	the	the	DT
cord-271972-qhr6iir6	215	18	Dom34p	Dom34p	NNP
cord-271972-qhr6iir6	215	19	endonuclease	endonuclease	NN
cord-271972-qhr6iir6	215	20	,	,	,
cord-271972-qhr6iir6	215	21	a	a	DT
cord-271972-qhr6iir6	215	22	key	key	JJ
cord-271972-qhr6iir6	215	23	component	component	NN
cord-271972-qhr6iir6	215	24	of	of	IN
cord-271972-qhr6iir6	215	25	a	a	DT
cord-271972-qhr6iir6	215	26	quality	quality	NN
cord-271972-qhr6iir6	215	27	control	control	NN
cord-271972-qhr6iir6	215	28	pathway	pathway	NN
cord-271972-qhr6iir6	215	29	termed	term	VBN
cord-271972-qhr6iir6	215	30	No	no	DT
cord-271972-qhr6iir6	215	31	-	-	HYPH
cord-271972-qhr6iir6	215	32	go	go	JJ
cord-271972-qhr6iir6	215	33	decay	decay	NN
cord-271972-qhr6iir6	215	34	(	(	-LRB-
cord-271972-qhr6iir6	215	35	NGD	NGD	NNP
cord-271972-qhr6iir6	215	36	)	)	-RRB-
cord-271972-qhr6iir6	215	37	.	.	.
cord-271972-qhr6iir6	216	1	NGD	NGD	NNP
cord-271972-qhr6iir6	216	2	is	be	VBZ
cord-271972-qhr6iir6	216	3	a	a	DT
cord-271972-qhr6iir6	216	4	surveillance	surveillance	NN
cord-271972-qhr6iir6	216	5	mechanism	mechanism	NN
cord-271972-qhr6iir6	216	6	that	that	WDT
cord-271972-qhr6iir6	216	7	targets	target	VBZ
cord-271972-qhr6iir6	216	8	mRNAs	mrnas	RP
cord-271972-qhr6iir6	216	9	with	with	IN
cord-271972-qhr6iir6	216	10	translation	translation	NN
cord-271972-qhr6iir6	216	11	-	-	HYPH
cord-271972-qhr6iir6	216	12	elongation	elongation	NN
cord-271972-qhr6iir6	216	13	stalls	stall	NNS
cord-271972-qhr6iir6	216	14	,	,	,
cord-271972-qhr6iir6	216	15	for	for	IN
cord-271972-qhr6iir6	216	16	example	example	NN
cord-271972-qhr6iir6	216	17	as	as	IN
cord-271972-qhr6iir6	216	18	a	a	DT
cord-271972-qhr6iir6	216	19	consequence	consequence	NN
cord-271972-qhr6iir6	216	20	of	of	IN
cord-271972-qhr6iir6	216	21	rare	rare	JJ
cord-271972-qhr6iir6	216	22	codons	codon	NNS
cord-271972-qhr6iir6	216	23	or	or	CC
cord-271972-qhr6iir6	216	24	strong	strong	JJ
cord-271972-qhr6iir6	216	25	secondary	secondary	JJ
cord-271972-qhr6iir6	216	26	structures	structure	NNS
cord-271972-qhr6iir6	216	27	.	.	.
cord-271972-qhr6iir6	217	1	Following	follow	VBG
cord-271972-qhr6iir6	217	2	endonucleolytic	endonucleolytic	JJ
cord-271972-qhr6iir6	217	3	cleavage	cleavage	NN
cord-271972-qhr6iir6	217	4	by	by	IN
cord-271972-qhr6iir6	217	5	Dom34p	Dom34p	NNP
cord-271972-qhr6iir6	217	6	,	,	,
cord-271972-qhr6iir6	217	7	the	the	DT
cord-271972-qhr6iir6	217	8	resulting	result	VBG
cord-271972-qhr6iir6	217	9	RNA	rna	NN
cord-271972-qhr6iir6	217	10	fragments	fragment	NNS
cord-271972-qhr6iir6	217	11	are	be	VBP
cord-271972-qhr6iir6	217	12	degraded	degrade	VBN
cord-271972-qhr6iir6	217	13	from	from	IN
cord-271972-qhr6iir6	217	14	the	the	DT
cord-271972-qhr6iir6	217	15	5	5	CD
cord-271972-qhr6iir6	217	16	end	end	NN
cord-271972-qhr6iir6	217	17	by	by	IN
cord-271972-qhr6iir6	217	18	the	the	DT
cord-271972-qhr6iir6	217	19	exonuclease	exonuclease	NN
cord-271972-qhr6iir6	217	20	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	217	21	and	and	CC
cord-271972-qhr6iir6	217	22	from	from	IN
cord-271972-qhr6iir6	217	23	the	the	DT
cord-271972-qhr6iir6	217	24	3	3	CD
cord-271972-qhr6iir6	217	25	end	end	NN
cord-271972-qhr6iir6	217	26	by	by	IN
cord-271972-qhr6iir6	217	27	the	the	DT
cord-271972-qhr6iir6	217	28	exosome	exosome	NN
cord-271972-qhr6iir6	217	29	72	72	CD
cord-271972-qhr6iir6	217	30	(	(	-LRB-
cord-271972-qhr6iir6	217	31	Figure	figure	NN
cord-271972-qhr6iir6	217	32	5	5	CD
cord-271972-qhr6iir6	217	33	)	)	-RRB-
cord-271972-qhr6iir6	217	34	.	.	.
cord-271972-qhr6iir6	218	1	As	as	IN
cord-271972-qhr6iir6	218	2	expected	expect	VBN
cord-271972-qhr6iir6	218	3	for	for	IN
cord-271972-qhr6iir6	218	4	NGD	NGD	NNP
cord-271972-qhr6iir6	218	5	,	,	,
cord-271972-qhr6iir6	218	6	yeast	yeast	NN
cord-271972-qhr6iir6	218	7	mutants	mutant	NNS
cord-271972-qhr6iir6	218	8	defective	defective	JJ
cord-271972-qhr6iir6	218	9	in	in	IN
cord-271972-qhr6iir6	218	10	Xrn1	Xrn1	NNP
cord-271972-qhr6iir6	218	11	or	or	CC
cord-271972-qhr6iir6	218	12	exosome	exosome	JJ
cord-271972-qhr6iir6	218	13	activity	activity	NN
cord-271972-qhr6iir6	218	14	accumulate	accumulate	VBP
cord-271972-qhr6iir6	218	15	cleaved	cleave	VBN
cord-271972-qhr6iir6	218	16	BMV	BMV	NNP
cord-271972-qhr6iir6	218	17	RNA	RNA	NNP
cord-271972-qhr6iir6	218	18	intermediates	intermediate	NNS
cord-271972-qhr6iir6	218	19	.	.	.
cord-271972-qhr6iir6	219	1	While	while	IN
cord-271972-qhr6iir6	219	2	NGD	NGD	NNP
cord-271972-qhr6iir6	219	3	has	have	VBZ
cord-271972-qhr6iir6	219	4	been	be	VBN
cord-271972-qhr6iir6	219	5	demonstrated	demonstrate	VBN
cord-271972-qhr6iir6	219	6	in	in	IN
cord-271972-qhr6iir6	219	7	yeast	yeast	NN
cord-271972-qhr6iir6	219	8	,	,	,
cord-271972-qhr6iir6	219	9	an	an	DT
cord-271972-qhr6iir6	219	10	analogous	analogous	JJ
cord-271972-qhr6iir6	219	11	surveillance	surveillance	NN
cord-271972-qhr6iir6	219	12	pathway	pathway	NN
cord-271972-qhr6iir6	219	13	in	in	IN
cord-271972-qhr6iir6	219	14	mammalian	mammalian	JJ
cord-271972-qhr6iir6	219	15	cells	cell	NNS
cord-271972-qhr6iir6	219	16	has	have	VBZ
cord-271972-qhr6iir6	219	17	yet	yet	RB
cord-271972-qhr6iir6	219	18	to	to	TO
cord-271972-qhr6iir6	219	19	be	be	VB
cord-271972-qhr6iir6	219	20	identified	identify	VBN
cord-271972-qhr6iir6	219	21	.	.	.
cord-271972-qhr6iir6	220	1	Thus	thus	RB
cord-271972-qhr6iir6	220	2	,	,	,
cord-271972-qhr6iir6	220	3	it	-PRON-	PRP
cord-271972-qhr6iir6	220	4	will	will	MD
cord-271972-qhr6iir6	220	5	be	be	VB
cord-271972-qhr6iir6	220	6	especially	especially	RB
cord-271972-qhr6iir6	220	7	interesting	interesting	JJ
cord-271972-qhr6iir6	220	8	to	to	TO
cord-271972-qhr6iir6	220	9	determine	determine	VB
cord-271972-qhr6iir6	220	10	whether	whether	IN
cord-271972-qhr6iir6	220	11	PAP	pap	NN
cord-271972-qhr6iir6	220	12	antiviral	antiviral	JJ
cord-271972-qhr6iir6	220	13	activity	activity	NN
cord-271972-qhr6iir6	220	14	against	against	IN
cord-271972-qhr6iir6	220	15	mammalian	mammalian	JJ
cord-271972-qhr6iir6	220	16	viruses	virus	NNS
cord-271972-qhr6iir6	220	17	similarly	similarly	RB
cord-271972-qhr6iir6	220	18	involves	involve	VBZ
cord-271972-qhr6iir6	220	19	depurination	depurination	NN
cord-271972-qhr6iir6	220	20	followed	follow	VBN
cord-271972-qhr6iir6	220	21	by	by	IN
cord-271972-qhr6iir6	220	22	translation	translation	NN
cord-271972-qhr6iir6	220	23	-	-	HYPH
cord-271972-qhr6iir6	220	24	dependent	dependent	JJ
cord-271972-qhr6iir6	220	25	RNA	RNA	NNP
cord-271972-qhr6iir6	220	26	turnover	turnover	NN
cord-271972-qhr6iir6	220	27	,	,	,
cord-271972-qhr6iir6	220	28	as	as	IN
cord-271972-qhr6iir6	220	29	this	this	DT
cord-271972-qhr6iir6	220	30	would	would	MD
cord-271972-qhr6iir6	220	31	provide	provide	VB
cord-271972-qhr6iir6	220	32	compelling	compelling	JJ
cord-271972-qhr6iir6	220	33	evidence	evidence	NN
cord-271972-qhr6iir6	220	34	for	for	IN
cord-271972-qhr6iir6	220	35	NGD	NGD	NNP
cord-271972-qhr6iir6	220	36	in	in	IN
cord-271972-qhr6iir6	220	37	humans	human	NNS
cord-271972-qhr6iir6	220	38	.	.	.
cord-271972-qhr6iir6	221	1	Along	along	IN
cord-271972-qhr6iir6	221	2	these	these	DT
cord-271972-qhr6iir6	221	3	lines	line	NNS
cord-271972-qhr6iir6	221	4	,	,	,
cord-271972-qhr6iir6	221	5	a	a	DT
cord-271972-qhr6iir6	221	6	recent	recent	JJ
cord-271972-qhr6iir6	221	7	study	study	NN
cord-271972-qhr6iir6	221	8	found	find	VBD
cord-271972-qhr6iir6	221	9	a	a	DT
cord-271972-qhr6iir6	221	10	reduction	reduction	NN
cord-271972-qhr6iir6	221	11	in	in	IN
cord-271972-qhr6iir6	221	12	the	the	DT
cord-271972-qhr6iir6	221	13	RNA	RNA	NNP
cord-271972-qhr6iir6	221	14	levels	level	NNS
cord-271972-qhr6iir6	221	15	of	of	IN
cord-271972-qhr6iir6	221	16	human	human	JJ
cord-271972-qhr6iir6	221	17	T	t	NN
cord-271972-qhr6iir6	221	18	-	-	HYPH
cord-271972-qhr6iir6	221	19	cell	cell	NN
cord-271972-qhr6iir6	221	20	leukemia	leukemia	NN
cord-271972-qhr6iir6	221	21	virus	virus	NN
cord-271972-qhr6iir6	221	22	type	type	NN
cord-271972-qhr6iir6	221	23	I	-PRON-	PRP
cord-271972-qhr6iir6	221	24	(	(	-LRB-
cord-271972-qhr6iir6	221	25	HTLV	HTLV	NNP
cord-271972-qhr6iir6	221	26	-	-	HYPH
cord-271972-qhr6iir6	221	27	I	I	NNP
cord-271972-qhr6iir6	221	28	)	)	-RRB-
cord-271972-qhr6iir6	221	29	,	,	,
cord-271972-qhr6iir6	221	30	as	as	RB
cord-271972-qhr6iir6	221	31	well	well	RB
cord-271972-qhr6iir6	221	32	as	as	IN
cord-271972-qhr6iir6	221	33	viral	viral	JJ
cord-271972-qhr6iir6	221	34	RNA	RNA	NNP
cord-271972-qhr6iir6	221	35	depurination	depurination	NN
cord-271972-qhr6iir6	221	36	,	,	,
cord-271972-qhr6iir6	221	37	in	in	IN
cord-271972-qhr6iir6	221	38	mammalian	mammalian	JJ
cord-271972-qhr6iir6	221	39	cells	cell	NNS
cord-271972-qhr6iir6	221	40	that	that	WDT
cord-271972-qhr6iir6	221	41	ectopically	ectopically	RB
cord-271972-qhr6iir6	221	42	express	express	VBP
cord-271972-qhr6iir6	221	43	PAP	pap	NN
cord-271972-qhr6iir6	221	44	.	.	.
cord-271972-qhr6iir6	222	1	73	73	CD
cord-271972-qhr6iir6	223	1	However	however	RB
cord-271972-qhr6iir6	223	2	,	,	,
cord-271972-qhr6iir6	223	3	unlike	unlike	IN
cord-271972-qhr6iir6	223	4	the	the	DT
cord-271972-qhr6iir6	223	5	situation	situation	NN
cord-271972-qhr6iir6	223	6	in	in	IN
cord-271972-qhr6iir6	223	7	yeast	yeast	NN
cord-271972-qhr6iir6	223	8	with	with	IN
cord-271972-qhr6iir6	223	9	BMV	BMV	NNP
cord-271972-qhr6iir6	223	10	,	,	,
cord-271972-qhr6iir6	223	11	HTLV	HTLV	NNP
cord-271972-qhr6iir6	223	12	-	-	HYPH
cord-271972-qhr6iir6	223	13	I	-PRON-	PRP
cord-271972-qhr6iir6	223	14	RNAs	rna	NNS
cord-271972-qhr6iir6	223	15	were	be	VBD
cord-271972-qhr6iir6	223	16	not	not	RB
cord-271972-qhr6iir6	223	17	destabilized	destabilize	VBN
cord-271972-qhr6iir6	223	18	,	,	,
cord-271972-qhr6iir6	223	19	arguing	argue	VBG
cord-271972-qhr6iir6	223	20	against	against	IN
cord-271972-qhr6iir6	223	21	an	an	DT
cord-271972-qhr6iir6	223	22	NGD	NGD	NNP
cord-271972-qhr6iir6	223	23	-	-	HYPH
cord-271972-qhr6iir6	223	24	like	like	JJ
cord-271972-qhr6iir6	223	25	mechanism	mechanism	NN
cord-271972-qhr6iir6	223	26	of	of	IN
cord-271972-qhr6iir6	223	27	suppression	suppression	NN
cord-271972-qhr6iir6	223	28	.	.	.
cord-271972-qhr6iir6	224	1	It	-PRON-	PRP
cord-271972-qhr6iir6	224	2	is	be	VBZ
cord-271972-qhr6iir6	224	3	noteworthy	noteworthy	JJ
cord-271972-qhr6iir6	224	4	that	that	IN
cord-271972-qhr6iir6	224	5	whereas	whereas	IN
cord-271972-qhr6iir6	224	6	a	a	DT
cord-271972-qhr6iir6	224	7	number	number	NN
cord-271972-qhr6iir6	224	8	of	of	IN
cord-271972-qhr6iir6	224	9	N	N	NNP
cord-271972-qhr6iir6	224	10	-	-	HYPH
cord-271972-qhr6iir6	224	11	glycosidases	glycosidases	NNP
cord-271972-qhr6iir6	224	12	that	that	WDT
cord-271972-qhr6iir6	224	13	depurinate	depurinate	NNP
cord-271972-qhr6iir6	224	14	rRNA	rRNA	NNP
cord-271972-qhr6iir6	224	15	have	have	VBP
cord-271972-qhr6iir6	224	16	been	be	VBN
cord-271972-qhr6iir6	224	17	described	describe	VBN
cord-271972-qhr6iir6	224	18	in	in	IN
cord-271972-qhr6iir6	224	19	plants	plant	NNS
cord-271972-qhr6iir6	224	20	,	,	,
cord-271972-qhr6iir6	224	21	74	74	CD
cord-271972-qhr6iir6	224	22	no	no	DT
cord-271972-qhr6iir6	224	23	such	such	JJ
cord-271972-qhr6iir6	224	24	protein	protein	NN
cord-271972-qhr6iir6	224	25	has	have	VBZ
cord-271972-qhr6iir6	224	26	been	be	VBN
cord-271972-qhr6iir6	224	27	reported	report	VBN
cord-271972-qhr6iir6	224	28	in	in	IN
cord-271972-qhr6iir6	224	29	animal	animal	NN
cord-271972-qhr6iir6	224	30	cells	cell	NNS
cord-271972-qhr6iir6	224	31	.	.	.
cord-271972-qhr6iir6	225	1	In	in	IN
cord-271972-qhr6iir6	225	2	addition	addition	NN
cord-271972-qhr6iir6	225	3	,	,	,
cord-271972-qhr6iir6	225	4	it	-PRON-	PRP
cord-271972-qhr6iir6	225	5	will	will	MD
cord-271972-qhr6iir6	225	6	be	be	VB
cord-271972-qhr6iir6	225	7	important	important	JJ
cord-271972-qhr6iir6	225	8	to	to	TO
cord-271972-qhr6iir6	225	9	elucidate	elucidate	VB
cord-271972-qhr6iir6	225	10	which	which	WDT
cord-271972-qhr6iir6	225	11	features	feature	NNS
cord-271972-qhr6iir6	225	12	differentiate	differentiate	VBP
cord-271972-qhr6iir6	225	13	PAP	pap	NN
cord-271972-qhr6iir6	225	14	-	-	HYPH
cord-271972-qhr6iir6	225	15	susceptible	susceptible	JJ
cord-271972-qhr6iir6	225	16	versus	versus	IN
cord-271972-qhr6iir6	225	17	non	non	JJ
cord-271972-qhr6iir6	225	18	-	-	JJ
cord-271972-qhr6iir6	225	19	susceptible	susceptible	JJ
cord-271972-qhr6iir6	225	20	RNAs	rna	NNS
cord-271972-qhr6iir6	225	21	in	in	IN
cord-271972-qhr6iir6	225	22	light	light	NN
cord-271972-qhr6iir6	225	23	of	of	IN
cord-271972-qhr6iir6	225	24	potential	potential	JJ
cord-271972-qhr6iir6	225	25	antiviral	antiviral	JJ
cord-271972-qhr6iir6	225	26	uses	use	NNS
cord-271972-qhr6iir6	225	27	for	for	IN
cord-271972-qhr6iir6	225	28	PAP	pap	NN
cord-271972-qhr6iir6	225	29	.	.	.
cord-271972-qhr6iir6	226	1	In	in	IN
cord-271972-qhr6iir6	226	2	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	226	3	cells	cell	NNS
cord-271972-qhr6iir6	226	4	,	,	,
cord-271972-qhr6iir6	226	5	endonucleases	endonuclease	NNS
cord-271972-qhr6iir6	226	6	are	be	VBP
cord-271972-qhr6iir6	226	7	critical	critical	JJ
cord-271972-qhr6iir6	226	8	components	component	NNS
cord-271972-qhr6iir6	226	9	of	of	IN
cord-271972-qhr6iir6	226	10	multiple	multiple	JJ
cord-271972-qhr6iir6	226	11	cytoplasmic	cytoplasmic	JJ
cord-271972-qhr6iir6	226	12	quality	quality	NN
cord-271972-qhr6iir6	226	13	control	control	NN
cord-271972-qhr6iir6	226	14	pathways	pathway	NNS
cord-271972-qhr6iir6	226	15	but	but	CC
cord-271972-qhr6iir6	226	16	may	may	MD
cord-271972-qhr6iir6	226	17	not	not	RB
cord-271972-qhr6iir6	226	18	be	be	VB
cord-271972-qhr6iir6	226	19	major	major	JJ
cord-271972-qhr6iir6	226	20	participants	participant	NNS
cord-271972-qhr6iir6	226	21	in	in	IN
cord-271972-qhr6iir6	226	22	basal	basal	NN
cord-271972-qhr6iir6	226	23	mRNA	mrna	NN
cord-271972-qhr6iir6	226	24	decay	decay	NN
cord-271972-qhr6iir6	226	25	.	.	.
cord-271972-qhr6iir6	227	1	However	however	RB
cord-271972-qhr6iir6	227	2	,	,	,
cord-271972-qhr6iir6	227	3	an	an	DT
cord-271972-qhr6iir6	227	4	interferon	interferon	NN
cord-271972-qhr6iir6	227	5	-	-	HYPH
cord-271972-qhr6iir6	227	6	inducible	inducible	JJ
cord-271972-qhr6iir6	227	7	riboendonuclease	riboendonuclease	NN
cord-271972-qhr6iir6	227	8	,	,	,
cord-271972-qhr6iir6	227	9	RNase	RNase	NNP
cord-271972-qhr6iir6	227	10	L	L	NNP
cord-271972-qhr6iir6	227	11	,	,	,
cord-271972-qhr6iir6	227	12	has	have	VBZ
cord-271972-qhr6iir6	227	13	important	important	JJ
cord-271972-qhr6iir6	227	14	roles	role	NNS
cord-271972-qhr6iir6	227	15	in	in	IN
cord-271972-qhr6iir6	227	16	the	the	DT
cord-271972-qhr6iir6	227	17	innate	innate	JJ
cord-271972-qhr6iir6	227	18	immune	immune	JJ
cord-271972-qhr6iir6	227	19	response	response	NN
cord-271972-qhr6iir6	227	20	to	to	IN
cord-271972-qhr6iir6	227	21	pathogens	pathogen	NNS
cord-271972-qhr6iir6	227	22	.	.	.
cord-271972-qhr6iir6	228	1	RNase	RNase	NNP
cord-271972-qhr6iir6	228	2	L	L	NNP
cord-271972-qhr6iir6	228	3	is	be	VBZ
cord-271972-qhr6iir6	228	4	activated	activate	VBN
cord-271972-qhr6iir6	228	5	in	in	IN
cord-271972-qhr6iir6	228	6	the	the	DT
cord-271972-qhr6iir6	228	7	presence	presence	NN
cord-271972-qhr6iir6	228	8	of	of	IN
cord-271972-qhr6iir6	228	9	dsRNA	dsrna	NN
cord-271972-qhr6iir6	228	10	,	,	,
cord-271972-qhr6iir6	228	11	a	a	DT
cord-271972-qhr6iir6	228	12	non	non	JJ
cord-271972-qhr6iir6	228	13	-	-	JJ
cord-271972-qhr6iir6	228	14	self	self	JJ
cord-271972-qhr6iir6	228	15	species	specie	NNS
cord-271972-qhr6iir6	228	16	often	often	RB
cord-271972-qhr6iir6	228	17	present	present	JJ
cord-271972-qhr6iir6	228	18	in	in	IN
cord-271972-qhr6iir6	228	19	virally	virally	RB
cord-271972-qhr6iir6	228	20	infected	infect	VBN
cord-271972-qhr6iir6	228	21	cells	cell	NNS
cord-271972-qhr6iir6	228	22	(	(	-LRB-
cord-271972-qhr6iir6	228	23	Figure	figure	NN
cord-271972-qhr6iir6	228	24	6	6	CD
cord-271972-qhr6iir6	228	25	)	)	-RRB-
cord-271972-qhr6iir6	228	26	(	(	-LRB-
cord-271972-qhr6iir6	228	27	reviewed	review	VBN
cord-271972-qhr6iir6	228	28	in	in	IN
cord-271972-qhr6iir6	228	29	Ref	Ref	NNP
cord-271972-qhr6iir6	228	30	75	75	CD
cord-271972-qhr6iir6	228	31	)	)	-RRB-
cord-271972-qhr6iir6	228	32	.	.	.
cord-271972-qhr6iir6	229	1	dsRNAs	dsrna	NNS
cord-271972-qhr6iir6	229	2	stimulate	stimulate	VBP
cord-271972-qhr6iir6	229	3	the	the	DT
cord-271972-qhr6iir6	229	4	activity	activity	NN
cord-271972-qhr6iir6	229	5	of	of	IN
cord-271972-qhr6iir6	229	6	2	2	CD
cord-271972-qhr6iir6	229	7	,	,	,
cord-271972-qhr6iir6	229	8	5	5	CD
cord-271972-qhr6iir6	229	9	-oligoadenylate	-oligoadenylate	JJ
cord-271972-qhr6iir6	229	10	synthetase	synthetase	NN
cord-271972-qhr6iir6	229	11	(	(	-LRB-
cord-271972-qhr6iir6	229	12	OAS	OAS	NNP
cord-271972-qhr6iir6	229	13	)	)	-RRB-
cord-271972-qhr6iir6	229	14	,	,	,
cord-271972-qhr6iir6	229	15	which	which	WDT
cord-271972-qhr6iir6	229	16	produces	produce	VBZ
cord-271972-qhr6iir6	229	17	the	the	DT
cord-271972-qhr6iir6	229	18	allosteric	allosteric	JJ
cord-271972-qhr6iir6	229	19	activator	activator	NN
cord-271972-qhr6iir6	229	20	for	for	IN
cord-271972-qhr6iir6	229	21	RNase	RNase	NNP
cord-271972-qhr6iir6	229	22	L	L	NNP
cord-271972-qhr6iir6	229	23	,	,	,
cord-271972-qhr6iir6	229	24	2	2	CD
cord-271972-qhr6iir6	229	25	-5	-5	CD
cord-271972-qhr6iir6	229	26	-oligoadenylate	-oligoadenylate	:
cord-271972-qhr6iir6	229	27	(	(	-LRB-
cord-271972-qhr6iir6	229	28	2	2	CD
cord-271972-qhr6iir6	229	29	-	-	HYPH
cord-271972-qhr6iir6	229	30	5A	5a	CD
cord-271972-qhr6iir6	229	31	)	)	-RRB-
cord-271972-qhr6iir6	229	32	.	.	.
cord-271972-qhr6iir6	230	1	Activated	activate	VBN
cord-271972-qhr6iir6	230	2	RNase	RNase	NNP
cord-271972-qhr6iir6	230	3	L	L	NNP
cord-271972-qhr6iir6	230	4	cleaves	cleave	VBZ
cord-271972-qhr6iir6	230	5	at	at	IN
cord-271972-qhr6iir6	230	6	UU	UU	NNP
cord-271972-qhr6iir6	230	7	and	and	CC
cord-271972-qhr6iir6	230	8	UA	UA	NNP
cord-271972-qhr6iir6	230	9	dinucleotides	dinucleotide	VBZ
cord-271972-qhr6iir6	230	10	and	and	CC
cord-271972-qhr6iir6	230	11	contributes	contribute	VBZ
cord-271972-qhr6iir6	230	12	to	to	IN
cord-271972-qhr6iir6	230	13	the	the	DT
cord-271972-qhr6iir6	230	14	host	host	NN
cord-271972-qhr6iir6	230	15	defense	defense	NN
cord-271972-qhr6iir6	230	16	by	by	IN
cord-271972-qhr6iir6	230	17	destroying	destroy	VBG
cord-271972-qhr6iir6	230	18	not	not	RB
cord-271972-qhr6iir6	230	19	only	only	RB
cord-271972-qhr6iir6	230	20	viral	viral	JJ
cord-271972-qhr6iir6	230	21	RNAs	rna	NNS
cord-271972-qhr6iir6	230	22	,	,	,
cord-271972-qhr6iir6	230	23	but	but	CC
cord-271972-qhr6iir6	230	24	also	also	RB
cord-271972-qhr6iir6	230	25	cellular	cellular	JJ
cord-271972-qhr6iir6	230	26	mRNAs	mrnas	XX
cord-271972-qhr6iir6	231	1	and	and	CC
cord-271972-qhr6iir6	231	2	rRNAs	rRNAs	.
cord-271972-qhr6iir6	232	1	that	that	WDT
cord-271972-qhr6iir6	232	2	are	be	VBP
cord-271972-qhr6iir6	232	3	needed	need	VBN
cord-271972-qhr6iir6	232	4	for	for	IN
cord-271972-qhr6iir6	232	5	viral	viral	JJ
cord-271972-qhr6iir6	232	6	replication	replication	NN
cord-271972-qhr6iir6	232	7	,	,	,
cord-271972-qhr6iir6	232	8	and	and	CC
cord-271972-qhr6iir6	232	9	by	by	IN
cord-271972-qhr6iir6	232	10	stimulating	stimulate	VBG
cord-271972-qhr6iir6	232	11	apoptosis	apoptosis	NN
cord-271972-qhr6iir6	232	12	.	.	.
cord-271972-qhr6iir6	233	1	In	in	IN
cord-271972-qhr6iir6	233	2	addition	addition	NN
cord-271972-qhr6iir6	233	3	,	,	,
cord-271972-qhr6iir6	233	4	cleavage	cleavage	NN
cord-271972-qhr6iir6	233	5	by	by	IN
cord-271972-qhr6iir6	233	6	RNase	RNase	NNP
cord-271972-qhr6iir6	233	7	L	L	NNP
cord-271972-qhr6iir6	233	8	liberates	liberate	VBZ
cord-271972-qhr6iir6	233	9	small	small	JJ
cord-271972-qhr6iir6	233	10	dsRNA	dsrna	NN
cord-271972-qhr6iir6	233	11	species	specie	NNS
cord-271972-qhr6iir6	233	12	that	that	WDT
cord-271972-qhr6iir6	233	13	activate	activate	VBP
cord-271972-qhr6iir6	233	14	the	the	DT
cord-271972-qhr6iir6	233	15	pattern	pattern	NN
cord-271972-qhr6iir6	233	16	recognition	recognition	NN
cord-271972-qhr6iir6	233	17	receptors	receptor	NNS
cord-271972-qhr6iir6	233	18	RIG	rig	NN
cord-271972-qhr6iir6	233	19	-	-	:
cord-271972-qhr6iir6	233	20	I	I	NNP
cord-271972-qhr6iir6	233	21	and	and	CC
cord-271972-qhr6iir6	233	22	Mda-5	Mda-5	NNP
cord-271972-qhr6iir6	233	23	,	,	,
cord-271972-qhr6iir6	233	24	leading	lead	VBG
cord-271972-qhr6iir6	233	25	to	to	IN
cord-271972-qhr6iir6	233	26	IFN	IFN	NNP
cord-271972-qhr6iir6	233	27	-	-	HYPH
cord-271972-qhr6iir6	233	28	β	β	NN
cord-271972-qhr6iir6	233	29	production	production	NN
cord-271972-qhr6iir6	233	30	and	and	CC
cord-271972-qhr6iir6	233	31	amplification	amplification	NN
cord-271972-qhr6iir6	233	32	of	of	IN
cord-271972-qhr6iir6	233	33	the	the	DT
cord-271972-qhr6iir6	233	34	antiviral	antiviral	JJ
cord-271972-qhr6iir6	233	35	interferon	interferon	NN
cord-271972-qhr6iir6	233	36	response	response	NN
cord-271972-qhr6iir6	233	37	.	.	.
cord-271972-qhr6iir6	234	1	76	76	CD
cord-271972-qhr6iir6	234	2	dsRNA	dsrna	NN
cord-271972-qhr6iir6	234	3	is	be	VBZ
cord-271972-qhr6iir6	234	4	most	most	RBS
cord-271972-qhr6iir6	234	5	often	often	RB
cord-271972-qhr6iir6	234	6	found	find	VBN
cord-271972-qhr6iir6	234	7	upon	upon	IN
cord-271972-qhr6iir6	234	8	infection	infection	NN
cord-271972-qhr6iir6	234	9	with	with	IN
cord-271972-qhr6iir6	234	10	RNA	RNA	NNP
cord-271972-qhr6iir6	234	11	viruses	virus	NNS
cord-271972-qhr6iir6	234	12	that	that	WDT
cord-271972-qhr6iir6	234	13	produce	produce	VBP
cord-271972-qhr6iir6	234	14	dsRNA	dsrna	NN
cord-271972-qhr6iir6	234	15	intermediates	intermediate	NNS
cord-271972-qhr6iir6	234	16	during	during	IN
cord-271972-qhr6iir6	234	17	genome	genome	NN
cord-271972-qhr6iir6	234	18	replication	replication	NN
cord-271972-qhr6iir6	234	19	,	,	,
cord-271972-qhr6iir6	234	20	although	although	IN
cord-271972-qhr6iir6	234	21	dsDNA	dsdna	JJ
cord-271972-qhr6iir6	234	22	viruses	virus	NNS
cord-271972-qhr6iir6	234	23	can	can	MD
cord-271972-qhr6iir6	234	24	also	also	RB
cord-271972-qhr6iir6	234	25	produce	produce	VB
cord-271972-qhr6iir6	234	26	dsRNA	dsrna	NN
cord-271972-qhr6iir6	234	27	due	due	IN
cord-271972-qhr6iir6	234	28	to	to	IN
cord-271972-qhr6iir6	234	29	annealing	anneal	VBG
cord-271972-qhr6iir6	234	30	of	of	IN
cord-271972-qhr6iir6	234	31	complementary	complementary	JJ
cord-271972-qhr6iir6	234	32	RNAs	rna	NNS
cord-271972-qhr6iir6	234	33	transcribed	transcribe	VBN
cord-271972-qhr6iir6	234	34	from	from	IN
cord-271972-qhr6iir6	234	35	opposite	opposite	JJ
cord-271972-qhr6iir6	234	36	strands	strand	NNS
cord-271972-qhr6iir6	234	37	of	of	IN
cord-271972-qhr6iir6	234	38	the	the	DT
cord-271972-qhr6iir6	234	39	genome	genome	NN
cord-271972-qhr6iir6	234	40	.	.	.
cord-271972-qhr6iir6	235	1	RNase	RNase	NNP
cord-271972-qhr6iir6	235	2	L	l	NN
cord-271972-qhr6iir6	235	3	-	-	HYPH
cord-271972-qhr6iir6	235	4	deficient	deficient	JJ
cord-271972-qhr6iir6	235	5	cells	cell	NNS
cord-271972-qhr6iir6	235	6	and	and	CC
cord-271972-qhr6iir6	235	7	mice	mouse	NNS
cord-271972-qhr6iir6	235	8	thus	thus	RB
cord-271972-qhr6iir6	235	9	exhibit	exhibit	VBP
cord-271972-qhr6iir6	235	10	increased	increase	VBN
cord-271972-qhr6iir6	235	11	susceptibility	susceptibility	NN
cord-271972-qhr6iir6	235	12	to	to	IN
cord-271972-qhr6iir6	235	13	infection	infection	NN
cord-271972-qhr6iir6	235	14	by	by	IN
cord-271972-qhr6iir6	235	15	several	several	JJ
cord-271972-qhr6iir6	235	16	viruses	virus	NNS
cord-271972-qhr6iir6	235	17	(	(	-LRB-
cord-271972-qhr6iir6	235	18	reviewed	review	VBN
cord-271972-qhr6iir6	235	19	in	in	IN
cord-271972-qhr6iir6	235	20	Ref	Ref	NNP
cord-271972-qhr6iir6	235	21	75	75	CD
cord-271972-qhr6iir6	235	22	)	)	-RRB-
cord-271972-qhr6iir6	235	23	including	include	VBG
cord-271972-qhr6iir6	235	24	encephalomyocarditis	encephalomyocarditis	NNP
cord-271972-qhr6iir6	235	25	virus	virus	NN
cord-271972-qhr6iir6	235	26	,	,	,
cord-271972-qhr6iir6	235	27	77	77	CD
cord-271972-qhr6iir6	235	28	SINV	SINV	NNP
cord-271972-qhr6iir6	235	29	,	,	,
cord-271972-qhr6iir6	235	30	78	78	CD
cord-271972-qhr6iir6	235	31	and	and	CC
cord-271972-qhr6iir6	235	32	Coxsackievirus	Coxsackievirus	NNP
cord-271972-qhr6iir6	235	33	B4	B4	NNP
cord-271972-qhr6iir6	235	34	.	.	.
cord-271972-qhr6iir6	236	1	79	79	CD
cord-271972-qhr6iir6	237	1	It	-PRON-	PRP
cord-271972-qhr6iir6	237	2	has	have	VBZ
cord-271972-qhr6iir6	237	3	also	also	RB
cord-271972-qhr6iir6	237	4	been	be	VBN
cord-271972-qhr6iir6	237	5	proposed	propose	VBN
cord-271972-qhr6iir6	237	6	that	that	IN
cord-271972-qhr6iir6	237	7	a	a	DT
cord-271972-qhr6iir6	237	8	human	human	JJ
cord-271972-qhr6iir6	237	9	reduction	reduction	NN
cord-271972-qhr6iir6	237	10	-	-	HYPH
cord-271972-qhr6iir6	237	11	of	of	IN
cord-271972-qhr6iir6	237	12	-	-	HYPH
cord-271972-qhr6iir6	237	13	function	function	NN
cord-271972-qhr6iir6	237	14	mutation	mutation	NN
cord-271972-qhr6iir6	237	15	in	in	IN
cord-271972-qhr6iir6	237	16	RNase	RNase	NNP
cord-271972-qhr6iir6	237	17	L	L	NNP
cord-271972-qhr6iir6	237	18	renders	render	VBZ
cord-271972-qhr6iir6	237	19	individuals	individual	NNS
cord-271972-qhr6iir6	237	20	more	more	RBR
cord-271972-qhr6iir6	237	21	susceptible	susceptible	JJ
cord-271972-qhr6iir6	237	22	to	to	IN
cord-271972-qhr6iir6	237	23	xenotropic	xenotropic	NNP
cord-271972-qhr6iir6	237	24	murine	murine	JJ
cord-271972-qhr6iir6	237	25	leukemia	leukemia	NN
cord-271972-qhr6iir6	237	26	-	-	HYPH
cord-271972-qhr6iir6	237	27	related	relate	VBN
cord-271972-qhr6iir6	237	28	virus	virus	NN
cord-271972-qhr6iir6	237	29	,	,	,
cord-271972-qhr6iir6	237	30	a	a	DT
cord-271972-qhr6iir6	237	31	retrovirus	retrovirus	NN
cord-271972-qhr6iir6	237	32	that	that	WDT
cord-271972-qhr6iir6	237	33	has	have	VBZ
cord-271972-qhr6iir6	237	34	been	be	VBN
cord-271972-qhr6iir6	237	35	linked	link	VBN
cord-271972-qhr6iir6	237	36	to	to	IN
cord-271972-qhr6iir6	237	37	prostate	prostate	NN
cord-271972-qhr6iir6	237	38	cancer	cancer	NN
cord-271972-qhr6iir6	237	39	and	and	CC
cord-271972-qhr6iir6	237	40	chronic	chronic	JJ
cord-271972-qhr6iir6	237	41	fatigue	fatigue	NN
cord-271972-qhr6iir6	237	42	syndrome	syndrome	NN
cord-271972-qhr6iir6	237	43	.	.	.
cord-271972-qhr6iir6	238	1	80	80	CD
cord-271972-qhr6iir6	238	2	,	,	,
cord-271972-qhr6iir6	238	3	81	81	CD
cord-271972-qhr6iir6	238	4	A	a	DT
cord-271972-qhr6iir6	238	5	recent	recent	JJ
cord-271972-qhr6iir6	238	6	report	report	NN
cord-271972-qhr6iir6	238	7	has	have	VBZ
cord-271972-qhr6iir6	238	8	shown	show	VBN
cord-271972-qhr6iir6	238	9	that	that	IN
cord-271972-qhr6iir6	238	10	in	in	IN
cord-271972-qhr6iir6	238	11	the	the	DT
cord-271972-qhr6iir6	238	12	absence	absence	NN
cord-271972-qhr6iir6	238	13	of	of	IN
cord-271972-qhr6iir6	238	14	RNase	RNase	NNP
cord-271972-qhr6iir6	238	15	L	L	NNP
cord-271972-qhr6iir6	238	16	,	,	,
cord-271972-qhr6iir6	238	17	mice	mouse	NNS
cord-271972-qhr6iir6	238	18	infected	infect	VBN
cord-271972-qhr6iir6	238	19	with	with	IN
cord-271972-qhr6iir6	238	20	a	a	DT
cord-271972-qhr6iir6	238	21	neurotropic	neurotropic	JJ
cord-271972-qhr6iir6	238	22	demyelinating	demyelinating	NN
cord-271972-qhr6iir6	238	23	strain	strain	NN
cord-271972-qhr6iir6	238	24	of	of	IN
cord-271972-qhr6iir6	238	25	mouse	mouse	NN
cord-271972-qhr6iir6	238	26	hepatitis	hepatitis	NN
cord-271972-qhr6iir6	238	27	virus	virus	NN
cord-271972-qhr6iir6	238	28	(	(	-LRB-
cord-271972-qhr6iir6	238	29	MHV	MHV	NNP
cord-271972-qhr6iir6	238	30	)	)	-RRB-
cord-271972-qhr6iir6	238	31	succumb	succumb	VBP
cord-271972-qhr6iir6	238	32	to	to	IN
cord-271972-qhr6iir6	238	33	CNS	CNS	NNP
cord-271972-qhr6iir6	238	34	encephalomyelitis	encephalomyelitis	NN
cord-271972-qhr6iir6	238	35	.	.	.
cord-271972-qhr6iir6	239	1	82	82	CD
cord-271972-qhr6iir6	240	1	Notably	notably	RB
cord-271972-qhr6iir6	240	2	,	,	,
cord-271972-qhr6iir6	240	3	the	the	DT
cord-271972-qhr6iir6	240	4	infected	infected	JJ
cord-271972-qhr6iir6	240	5	RNase	RNase	NNP
cord-271972-qhr6iir6	240	6	L-/-mice	L-/-mice	NNP
cord-271972-qhr6iir6	240	7	did	do	VBD
cord-271972-qhr6iir6	240	8	not	not	RB
cord-271972-qhr6iir6	240	9	exhibit	exhibit	VB
cord-271972-qhr6iir6	240	10	increased	increase	VBN
cord-271972-qhr6iir6	240	11	neuronal	neuronal	JJ
cord-271972-qhr6iir6	240	12	infection	infection	NN
cord-271972-qhr6iir6	240	13	,	,	,
cord-271972-qhr6iir6	240	14	interferon	interferon	NN
cord-271972-qhr6iir6	240	15	induction	induction	NN
cord-271972-qhr6iir6	240	16	,	,	,
cord-271972-qhr6iir6	240	17	or	or	CC
cord-271972-qhr6iir6	240	18	viral	viral	JJ
cord-271972-qhr6iir6	240	19	titers	titer	NNS
cord-271972-qhr6iir6	240	20	;	;	:
cord-271972-qhr6iir6	240	21	mortality	mortality	NN
cord-271972-qhr6iir6	240	22	upon	upon	IN
cord-271972-qhr6iir6	240	23	infection	infection	NN
cord-271972-qhr6iir6	240	24	correlated	correlate	VBN
cord-271972-qhr6iir6	240	25	instead	instead	RB
cord-271972-qhr6iir6	240	26	with	with	IN
cord-271972-qhr6iir6	240	27	advanced	advanced	JJ
cord-271972-qhr6iir6	240	28	demyelination	demyelination	NN
cord-271972-qhr6iir6	240	29	and	and	CC
cord-271972-qhr6iir6	240	30	CNS	cns	JJ
cord-271972-qhr6iir6	240	31	tissue	tissue	NN
cord-271972-qhr6iir6	240	32	damage	damage	NN
cord-271972-qhr6iir6	240	33	.	.	.
cord-271972-qhr6iir6	241	1	Thus	thus	RB
cord-271972-qhr6iir6	241	2	,	,	,
cord-271972-qhr6iir6	241	3	RNase	RNase	NNP
cord-271972-qhr6iir6	241	4	L	L	NNP
cord-271972-qhr6iir6	241	5	somehow	somehow	RB
cord-271972-qhr6iir6	241	6	prevents	prevent	VBZ
cord-271972-qhr6iir6	241	7	extended	extend	VBN
cord-271972-qhr6iir6	241	8	and	and	CC
cord-271972-qhr6iir6	241	9	sustained	sustain	VBN
cord-271972-qhr6iir6	241	10	CNS	CNS	NNP
cord-271972-qhr6iir6	241	11	tropism	tropism	NN
cord-271972-qhr6iir6	241	12	of	of	IN
cord-271972-qhr6iir6	241	13	MHV	MHV	NNP
cord-271972-qhr6iir6	241	14	.	.	.
cord-271972-qhr6iir6	242	1	The	the	DT
cord-271972-qhr6iir6	242	2	dramatic	dramatic	JJ
cord-271972-qhr6iir6	242	3	effects	effect	NNS
cord-271972-qhr6iir6	242	4	of	of	IN
cord-271972-qhr6iir6	242	5	such	such	JJ
cord-271972-qhr6iir6	242	6	subtle	subtle	JJ
cord-271972-qhr6iir6	242	7	tropism	tropism	NN
cord-271972-qhr6iir6	242	8	alterations	alteration	NNS
cord-271972-qhr6iir6	242	9	highlight	highlight	VBP
cord-271972-qhr6iir6	242	10	both	both	CC
cord-271972-qhr6iir6	242	11	the	the	DT
cord-271972-qhr6iir6	242	12	diversity	diversity	NN
cord-271972-qhr6iir6	242	13	of	of	IN
cord-271972-qhr6iir6	242	14	RNase	RNase	NNP
cord-271972-qhr6iir6	242	15	L	L	NNP
cord-271972-qhr6iir6	242	16	functions	function	NNS
cord-271972-qhr6iir6	242	17	as	as	RB
cord-271972-qhr6iir6	242	18	well	well	RB
cord-271972-qhr6iir6	242	19	as	as	IN
cord-271972-qhr6iir6	242	20	its	-PRON-	PRP$
cord-271972-qhr6iir6	242	21	complex	complex	JJ
cord-271972-qhr6iir6	242	22	interactions	interaction	NNS
cord-271972-qhr6iir6	242	23	with	with	IN
cord-271972-qhr6iir6	242	24	infecting	infect	VBG
cord-271972-qhr6iir6	242	25	viruses	virus	NNS
cord-271972-qhr6iir6	242	26	.	.	.
cord-271972-qhr6iir6	243	1	Not	not	RB
cord-271972-qhr6iir6	243	2	surprisingly	surprisingly	RB
cord-271972-qhr6iir6	243	3	,	,	,
cord-271972-qhr6iir6	243	4	many	many	JJ
cord-271972-qhr6iir6	243	5	viruses	virus	NNS
cord-271972-qhr6iir6	243	6	have	have	VBP
cord-271972-qhr6iir6	243	7	evolved	evolve	VBN
cord-271972-qhr6iir6	243	8	mechanisms	mechanism	NNS
cord-271972-qhr6iir6	243	9	to	to	TO
cord-271972-qhr6iir6	243	10	blunt	blunt	VB
cord-271972-qhr6iir6	243	11	the	the	DT
cord-271972-qhr6iir6	243	12	activation	activation	NN
cord-271972-qhr6iir6	243	13	of	of	IN
cord-271972-qhr6iir6	243	14	RNase	RNase	NNP
cord-271972-qhr6iir6	243	15	L	L	NNP
cord-271972-qhr6iir6	243	16	,	,	,
cord-271972-qhr6iir6	243	17	and	and	CC
cord-271972-qhr6iir6	243	18	such	such	JJ
cord-271972-qhr6iir6	243	19	inactivation	inactivation	NN
cord-271972-qhr6iir6	243	20	occurs	occur	VBZ
cord-271972-qhr6iir6	243	21	at	at	IN
cord-271972-qhr6iir6	243	22	a	a	DT
cord-271972-qhr6iir6	243	23	variety	variety	NN
cord-271972-qhr6iir6	243	24	of	of	IN
cord-271972-qhr6iir6	243	25	different	different	JJ
cord-271972-qhr6iir6	243	26	steps	step	NNS
cord-271972-qhr6iir6	243	27	in	in	IN
cord-271972-qhr6iir6	243	28	the	the	DT
cord-271972-qhr6iir6	243	29	RNase	RNase	NNP
cord-271972-qhr6iir6	243	30	L	L	NNP
cord-271972-qhr6iir6	243	31	pathway	pathway	NN
cord-271972-qhr6iir6	243	32	(	(	-LRB-
cord-271972-qhr6iir6	243	33	Figure	Figure	NNP
cord-271972-qhr6iir6	243	34	6	6	CD
cord-271972-qhr6iir6	243	35	)	)	-RRB-
cord-271972-qhr6iir6	243	36	.	.	.
cord-271972-qhr6iir6	244	1	The	the	DT
cord-271972-qhr6iir6	244	2	NS1	ns1	NN
cord-271972-qhr6iir6	244	3	protein	protein	NN
cord-271972-qhr6iir6	244	4	of	of	IN
cord-271972-qhr6iir6	244	5	influenza	influenza	NN
cord-271972-qhr6iir6	244	6	A	a	DT
cord-271972-qhr6iir6	244	7	virus	virus	NN
cord-271972-qhr6iir6	244	8	,	,	,
cord-271972-qhr6iir6	244	9	for	for	IN
cord-271972-qhr6iir6	244	10	example	example	NN
cord-271972-qhr6iir6	244	11	,	,	,
cord-271972-qhr6iir6	244	12	acts	act	VBZ
cord-271972-qhr6iir6	244	13	at	at	IN
cord-271972-qhr6iir6	244	14	a	a	DT
cord-271972-qhr6iir6	244	15	very	very	RB
cord-271972-qhr6iir6	244	16	early	early	JJ
cord-271972-qhr6iir6	244	17	step	step	NN
cord-271972-qhr6iir6	244	18	by	by	IN
cord-271972-qhr6iir6	244	19	coating	coat	VBG
cord-271972-qhr6iir6	244	20	dsRNA	dsRNA	NNS
cord-271972-qhr6iir6	244	21	and	and	CC
cord-271972-qhr6iir6	244	22	thereby	thereby	RB
cord-271972-qhr6iir6	244	23	preventing	prevent	VBG
cord-271972-qhr6iir6	244	24	these	these	DT
cord-271972-qhr6iir6	244	25	species	specie	NNS
cord-271972-qhr6iir6	244	26	from	from	IN
cord-271972-qhr6iir6	244	27	activating	activate	VBG
cord-271972-qhr6iir6	244	28	OAS	OAS	NNP
cord-271972-qhr6iir6	244	29	.	.	.
cord-271972-qhr6iir6	245	1	83	83	CD
cord-271972-qhr6iir6	245	2	potently	potently	RB
cord-271972-qhr6iir6	245	3	induces	induce	VBZ
cord-271972-qhr6iir6	245	4	2	2	CD
cord-271972-qhr6iir6	245	5	-	-	HYPH
cord-271972-qhr6iir6	245	6	5A	5a	CD
cord-271972-qhr6iir6	245	7	production	production	NN
cord-271972-qhr6iir6	245	8	,	,	,
cord-271972-qhr6iir6	245	9	but	but	CC
cord-271972-qhr6iir6	245	10	subsequent	subsequent	JJ
cord-271972-qhr6iir6	245	11	RNase	RNase	NNP
cord-271972-qhr6iir6	245	12	L	L	NNP
cord-271972-qhr6iir6	245	13	activation	activation	NN
cord-271972-qhr6iir6	245	14	is	be	VBZ
cord-271972-qhr6iir6	245	15	blocked	block	VBN
cord-271972-qhr6iir6	245	16	.	.	.
cord-271972-qhr6iir6	246	1	75	75	CD
cord-271972-qhr6iir6	246	2	,	,	,
cord-271972-qhr6iir6	246	3	85	85	CD
cord-271972-qhr6iir6	246	4	,	,	,
cord-271972-qhr6iir6	246	5	86	86	CD
cord-271972-qhr6iir6	247	1	In	in	IN
cord-271972-qhr6iir6	247	2	the	the	DT
cord-271972-qhr6iir6	247	3	case	case	NN
cord-271972-qhr6iir6	247	4	of	of	IN
cord-271972-qhr6iir6	247	5	HIV-1	HIV-1	NNP
cord-271972-qhr6iir6	247	6	,	,	,
cord-271972-qhr6iir6	247	7	it	-PRON-	PRP
cord-271972-qhr6iir6	247	8	appears	appear	VBZ
cord-271972-qhr6iir6	247	9	that	that	IN
cord-271972-qhr6iir6	247	10	this	this	DT
cord-271972-qhr6iir6	247	11	is	be	VBZ
cord-271972-qhr6iir6	247	12	accomplished	accomplish	VBN
cord-271972-qhr6iir6	247	13	by	by	IN
cord-271972-qhr6iir6	247	14	somehow	somehow	RB
cord-271972-qhr6iir6	247	15	decreasing	decrease	VBG
cord-271972-qhr6iir6	247	16	the	the	DT
cord-271972-qhr6iir6	247	17	affinity	affinity	NN
cord-271972-qhr6iir6	247	18	of	of	IN
cord-271972-qhr6iir6	247	19	RNase	RNase	NNP
cord-271972-qhr6iir6	247	20	L	l	NN
cord-271972-qhr6iir6	247	21	for	for	IN
cord-271972-qhr6iir6	247	22	2	2	CD
cord-271972-qhr6iir6	247	23	-	-	HYPH
cord-271972-qhr6iir6	247	24	5A	5a	NN
cord-271972-qhr6iir6	247	25	(	(	-LRB-
cord-271972-qhr6iir6	247	26	reviewed	review	VBN
cord-271972-qhr6iir6	247	27	in	in	IN
cord-271972-qhr6iir6	247	28	Ref	Ref	NNP
cord-271972-qhr6iir6	247	29	85	85	CD
cord-271972-qhr6iir6	247	30	)	)	-RRB-
cord-271972-qhr6iir6	247	31	.	.	.
cord-271972-qhr6iir6	248	1	Some	some	DT
cord-271972-qhr6iir6	248	2	viruses	virus	NNS
cord-271972-qhr6iir6	248	3	,	,	,
cord-271972-qhr6iir6	248	4	like	like	IN
cord-271972-qhr6iir6	248	5	HCV	HCV	NNP
cord-271972-qhr6iir6	248	6	and	and	CC
cord-271972-qhr6iir6	248	7	PV	PV	NNP
cord-271972-qhr6iir6	248	8	,	,	,
cord-271972-qhr6iir6	248	9	do	do	VBP
cord-271972-qhr6iir6	248	10	not	not	RB
cord-271972-qhr6iir6	248	11	block	block	VB
cord-271972-qhr6iir6	248	12	RNase	RNase	NNP
cord-271972-qhr6iir6	248	13	L	L	NNP
cord-271972-qhr6iir6	248	14	activation	activation	NN
cord-271972-qhr6iir6	248	15	,	,	,
cord-271972-qhr6iir6	248	16	but	but	CC
cord-271972-qhr6iir6	248	17	their	-PRON-	PRP$
cord-271972-qhr6iir6	248	18	RNAs	rna	NNS
cord-271972-qhr6iir6	248	19	still	still	RB
cord-271972-qhr6iir6	248	20	escape	escape	VBP
cord-271972-qhr6iir6	248	21	degradation	degradation	NN
cord-271972-qhr6iir6	248	22	by	by	IN
cord-271972-qhr6iir6	248	23	this	this	DT
cord-271972-qhr6iir6	248	24	endonuclease	endonuclease	NN
cord-271972-qhr6iir6	248	25	.	.	.
cord-271972-qhr6iir6	249	1	It	-PRON-	PRP
cord-271972-qhr6iir6	249	2	has	have	VBZ
cord-271972-qhr6iir6	249	3	been	be	VBN
cord-271972-qhr6iir6	249	4	shown	show	VBN
cord-271972-qhr6iir6	249	5	that	that	IN
cord-271972-qhr6iir6	249	6	select	select	JJ
cord-271972-qhr6iir6	249	7	genotypes	genotype	NNS
cord-271972-qhr6iir6	249	8	of	of	IN
cord-271972-qhr6iir6	249	9	HCV	HCV	NNP
cord-271972-qhr6iir6	249	10	avoid	avoid	VB
cord-271972-qhr6iir6	249	11	RNase	RNase	NNP
cord-271972-qhr6iir6	249	12	L	L	NNP
cord-271972-qhr6iir6	249	13	cleavage	cleavage	NN
cord-271972-qhr6iir6	249	14	by	by	IN
cord-271972-qhr6iir6	249	15	suppressing	suppress	VBG
cord-271972-qhr6iir6	249	16	the	the	DT
cord-271972-qhr6iir6	249	17	frequency	frequency	NN
cord-271972-qhr6iir6	249	18	of	of	IN
cord-271972-qhr6iir6	249	19	UU	UU	NNP
cord-271972-qhr6iir6	249	20	and	and	CC
cord-271972-qhr6iir6	249	21	UA	UA	NNP
cord-271972-qhr6iir6	249	22	sequences	sequence	NNS
cord-271972-qhr6iir6	249	23	in	in	IN
cord-271972-qhr6iir6	249	24	their	-PRON-	PRP$
cord-271972-qhr6iir6	249	25	genome	genome	NN
cord-271972-qhr6iir6	249	26	,	,	,
cord-271972-qhr6iir6	249	27	perhaps	perhaps	RB
cord-271972-qhr6iir6	249	28	as	as	IN
cord-271972-qhr6iir6	249	29	a	a	DT
cord-271972-qhr6iir6	249	30	consequence	consequence	NN
cord-271972-qhr6iir6	249	31	of	of	IN
cord-271972-qhr6iir6	249	32	selective	selective	JJ
cord-271972-qhr6iir6	249	33	evolutionary	evolutionary	JJ
cord-271972-qhr6iir6	249	34	pressure	pressure	NN
cord-271972-qhr6iir6	249	35	.	.	.
cord-271972-qhr6iir6	250	1	87	87	CD
cord-271972-qhr6iir6	250	2	HCV	HCV	NNP
cord-271972-qhr6iir6	250	3	genotypes	genotype	NNS
cord-271972-qhr6iir6	250	4	in	in	IN
cord-271972-qhr6iir6	250	5	the	the	DT
cord-271972-qhr6iir6	250	6	human	human	JJ
cord-271972-qhr6iir6	250	7	population	population	NN
cord-271972-qhr6iir6	250	8	that	that	WDT
cord-271972-qhr6iir6	250	9	are	be	VBP
cord-271972-qhr6iir6	250	10	less	less	RBR
cord-271972-qhr6iir6	250	11	sensitive	sensitive	JJ
cord-271972-qhr6iir6	250	12	to	to	IN
cord-271972-qhr6iir6	250	13	RNase	RNase	NNP
cord-271972-qhr6iir6	250	14	L	L	NNP
cord-271972-qhr6iir6	250	15	also	also	RB
cord-271972-qhr6iir6	250	16	show	show	VB
cord-271972-qhr6iir6	250	17	increased	increase	VBN
cord-271972-qhr6iir6	250	18	interferon	interferon	NN
cord-271972-qhr6iir6	250	19	resistance	resistance	NN
cord-271972-qhr6iir6	250	20	.	.	.
cord-271972-qhr6iir6	251	1	87	87	CD
cord-271972-qhr6iir6	252	1	Conversely	conversely	RB
cord-271972-qhr6iir6	252	2	,	,	,
cord-271972-qhr6iir6	252	3	the	the	DT
cord-271972-qhr6iir6	252	4	PV	PV	NNP
cord-271972-qhr6iir6	252	5	genome	genome	NN
cord-271972-qhr6iir6	252	6	is	be	VBZ
cord-271972-qhr6iir6	252	7	very	very	RB
cord-271972-qhr6iir6	252	8	UU	UU	NNP
cord-271972-qhr6iir6	252	9	/	/	SYM
cord-271972-qhr6iir6	252	10	UA	UA	NNP
cord-271972-qhr6iir6	252	11	rich	rich	JJ
cord-271972-qhr6iir6	252	12	,	,	,
cord-271972-qhr6iir6	252	13	but	but	CC
cord-271972-qhr6iir6	252	14	is	be	VBZ
cord-271972-qhr6iir6	252	15	still	still	RB
cord-271972-qhr6iir6	252	16	surprisingly	surprisingly	RB
cord-271972-qhr6iir6	252	17	resistant	resistant	JJ
cord-271972-qhr6iir6	252	18	to	to	IN
cord-271972-qhr6iir6	252	19	RNase	RNase	NNP
cord-271972-qhr6iir6	252	20	L	L	NNP
cord-271972-qhr6iir6	252	21	cleavage	cleavage	NN
cord-271972-qhr6iir6	252	22	because	because	IN
cord-271972-qhr6iir6	252	23	of	of	IN
cord-271972-qhr6iir6	252	24	a	a	DT
cord-271972-qhr6iir6	252	25	structural	structural	JJ
cord-271972-qhr6iir6	252	26	element	element	NN
cord-271972-qhr6iir6	252	27	present	present	JJ
cord-271972-qhr6iir6	252	28	within	within	IN
cord-271972-qhr6iir6	252	29	the	the	DT
cord-271972-qhr6iir6	252	30	PV	PV	NNP
cord-271972-qhr6iir6	252	31	RNA2	RNA2	NNP
cord-271972-qhr6iir6	252	32	ORF	ORF	NNP
cord-271972-qhr6iir6	252	33	.	.	.
cord-271972-qhr6iir6	253	1	88	88	CD
cord-271972-qhr6iir6	254	1	This	this	DT
cord-271972-qhr6iir6	254	2	element	element	NN
cord-271972-qhr6iir6	254	3	functions	function	VBZ
cord-271972-qhr6iir6	254	4	as	as	IN
cord-271972-qhr6iir6	254	5	a	a	DT
cord-271972-qhr6iir6	254	6	competitive	competitive	JJ
cord-271972-qhr6iir6	254	7	inhibitor	inhibitor	NN
cord-271972-qhr6iir6	254	8	of	of	IN
cord-271972-qhr6iir6	254	9	RNase	RNase	NNP
cord-271972-qhr6iir6	254	10	L	L	NNP
cord-271972-qhr6iir6	254	11	thereby	thereby	RB
cord-271972-qhr6iir6	254	12	directly	directly	RB
cord-271972-qhr6iir6	254	13	blocking	block	VBG
cord-271972-qhr6iir6	254	14	its	-PRON-	PRP$
cord-271972-qhr6iir6	254	15	enzymatic	enzymatic	JJ
cord-271972-qhr6iir6	254	16	activity	activity	NN
cord-271972-qhr6iir6	254	17	.	.	.
cord-271972-qhr6iir6	255	1	89	89	CD
cord-271972-qhr6iir6	256	1	The	the	DT
cord-271972-qhr6iir6	256	2	role	role	NN
cord-271972-qhr6iir6	256	3	of	of	IN
cord-271972-qhr6iir6	256	4	RNase	RNase	NNP
cord-271972-qhr6iir6	256	5	L	L	NNP
cord-271972-qhr6iir6	256	6	inhibition	inhibition	NN
cord-271972-qhr6iir6	256	7	during	during	IN
cord-271972-qhr6iir6	256	8	PV	PV	NNP
cord-271972-qhr6iir6	256	9	infection	infection	NN
cord-271972-qhr6iir6	256	10	remains	remain	VBZ
cord-271972-qhr6iir6	256	11	unclear	unclear	JJ
cord-271972-qhr6iir6	256	12	,	,	,
cord-271972-qhr6iir6	256	13	however	however	RB
cord-271972-qhr6iir6	256	14	,	,	,
cord-271972-qhr6iir6	256	15	as	as	IN
cord-271972-qhr6iir6	256	16	PV	pv	NN
cord-271972-qhr6iir6	256	17	carrying	carrying	NN
cord-271972-qhr6iir6	256	18	mutations	mutation	NNS
cord-271972-qhr6iir6	256	19	that	that	WDT
cord-271972-qhr6iir6	256	20	prevent	prevent	VBP
cord-271972-qhr6iir6	256	21	the	the	DT
cord-271972-qhr6iir6	256	22	formation	formation	NN
cord-271972-qhr6iir6	256	23	of	of	IN
cord-271972-qhr6iir6	256	24	the	the	DT
cord-271972-qhr6iir6	256	25	inhibitory	inhibitory	JJ
cord-271972-qhr6iir6	256	26	structural	structural	JJ
cord-271972-qhr6iir6	256	27	element	element	NN
cord-271972-qhr6iir6	256	28	replicate	replicate	VBP
cord-271972-qhr6iir6	256	29	to	to	IN
cord-271972-qhr6iir6	256	30	wild	wild	JJ
cord-271972-qhr6iir6	256	31	-	-	HYPH
cord-271972-qhr6iir6	256	32	type	type	NN
cord-271972-qhr6iir6	256	33	levels	level	NNS
cord-271972-qhr6iir6	256	34	in	in	IN
cord-271972-qhr6iir6	256	35	cell	cell	NN
cord-271972-qhr6iir6	256	36	culture	culture	NN
cord-271972-qhr6iir6	256	37	,	,	,
cord-271972-qhr6iir6	256	38	and	and	CC
cord-271972-qhr6iir6	256	39	do	do	VBP
cord-271972-qhr6iir6	256	40	not	not	RB
cord-271972-qhr6iir6	256	41	exhibit	exhibit	VB
cord-271972-qhr6iir6	256	42	increased	increase	VBN
cord-271972-qhr6iir6	256	43	sensitivity	sensitivity	NN
cord-271972-qhr6iir6	256	44	to	to	IN
cord-271972-qhr6iir6	256	45	interferon	interferon	NN
cord-271972-qhr6iir6	256	46	.	.	.
cord-271972-qhr6iir6	257	1	88	88	CD
cord-271972-qhr6iir6	258	1	Although	although	IN
cord-271972-qhr6iir6	258	2	the	the	DT
cord-271972-qhr6iir6	258	3	above	above	JJ
cord-271972-qhr6iir6	258	4	examples	example	NNS
cord-271972-qhr6iir6	258	5	highlight	highlight	VBP
cord-271972-qhr6iir6	258	6	RNase	RNase	NNP
cord-271972-qhr6iir6	258	7	L	L	NNP
cord-271972-qhr6iir6	258	8	as	as	IN
cord-271972-qhr6iir6	258	9	an	an	DT
cord-271972-qhr6iir6	258	10	antiviral	antiviral	JJ
cord-271972-qhr6iir6	258	11	protein	protein	NN
cord-271972-qhr6iir6	258	12	,	,	,
cord-271972-qhr6iir6	258	13	in	in	IN
cord-271972-qhr6iir6	258	14	some	some	DT
cord-271972-qhr6iir6	258	15	cases	case	NNS
cord-271972-qhr6iir6	258	16	it	-PRON-	PRP
cord-271972-qhr6iir6	258	17	may	may	MD
cord-271972-qhr6iir6	258	18	facilitate	facilitate	VB
cord-271972-qhr6iir6	258	19	viral	viral	JJ
cord-271972-qhr6iir6	258	20	replication	replication	NN
cord-271972-qhr6iir6	258	21	and/or	and/or	CC
cord-271972-qhr6iir6	258	22	dissemination	dissemination	NN
cord-271972-qhr6iir6	258	23	.	.	.
cord-271972-qhr6iir6	259	1	For	for	IN
cord-271972-qhr6iir6	259	2	example	example	NN
cord-271972-qhr6iir6	259	3	,	,	,
cord-271972-qhr6iir6	259	4	PV	PV	NNP
cord-271972-qhr6iir6	259	5	forms	form	VBZ
cord-271972-qhr6iir6	259	6	larger	large	JJR
cord-271972-qhr6iir6	259	7	plaques	plaque	NNS
cord-271972-qhr6iir6	259	8	if	if	IN
cord-271972-qhr6iir6	259	9	cultured	culture	VBN
cord-271972-qhr6iir6	259	10	in	in	IN
cord-271972-qhr6iir6	259	11	cells	cell	NNS
cord-271972-qhr6iir6	259	12	overexpressing	overexpresse	VBG
cord-271972-qhr6iir6	259	13	wild	wild	JJ
cord-271972-qhr6iir6	259	14	-	-	HYPH
cord-271972-qhr6iir6	259	15	type	type	NN
cord-271972-qhr6iir6	259	16	RNase	rnase	NN
cord-271972-qhr6iir6	259	17	L	l	NN
cord-271972-qhr6iir6	259	18	,	,	,
cord-271972-qhr6iir6	259	19	and	and	CC
cord-271972-qhr6iir6	259	20	smaller	small	JJR
cord-271972-qhr6iir6	259	21	plaques	plaque	NNS
cord-271972-qhr6iir6	259	22	in	in	IN
cord-271972-qhr6iir6	259	23	cells	cell	NNS
cord-271972-qhr6iir6	259	24	overexpressing	overexpresse	VBG
cord-271972-qhr6iir6	259	25	a	a	DT
cord-271972-qhr6iir6	259	26	dominant	dominant	JJ
cord-271972-qhr6iir6	259	27	-	-	HYPH
cord-271972-qhr6iir6	259	28	negative	negative	JJ
cord-271972-qhr6iir6	259	29	form	form	NN
cord-271972-qhr6iir6	259	30	of	of	IN
cord-271972-qhr6iir6	259	31	the	the	DT
cord-271972-qhr6iir6	259	32	protein	protein	NN
cord-271972-qhr6iir6	259	33	.	.	.
cord-271972-qhr6iir6	260	1	88	88	CD
cord-271972-qhr6iir6	261	1	It	-PRON-	PRP
cord-271972-qhr6iir6	261	2	has	have	VBZ
cord-271972-qhr6iir6	261	3	been	be	VBN
cord-271972-qhr6iir6	261	4	hypothesized	hypothesize	VBN
cord-271972-qhr6iir6	261	5	that	that	IN
cord-271972-qhr6iir6	261	6	PV	PV	NNP
cord-271972-qhr6iir6	261	7	selectively	selectively	RB
cord-271972-qhr6iir6	261	8	inhibits	inhibit	VBZ
cord-271972-qhr6iir6	261	9	RNase	RNase	NNP
cord-271972-qhr6iir6	261	10	L	L	NNP
cord-271972-qhr6iir6	261	11	early	early	RB
cord-271972-qhr6iir6	261	12	in	in	IN
cord-271972-qhr6iir6	261	13	infection	infection	NN
cord-271972-qhr6iir6	261	14	,	,	,
cord-271972-qhr6iir6	261	15	but	but	CC
cord-271972-qhr6iir6	261	16	then	then	RB
cord-271972-qhr6iir6	261	17	uses	use	VBZ
cord-271972-qhr6iir6	261	18	RNase	RNase	NNP
cord-271972-qhr6iir6	261	19	L	l	NN
cord-271972-qhr6iir6	261	20	-	-	HYPH
cord-271972-qhr6iir6	261	21	induced	induce	VBN
cord-271972-qhr6iir6	261	22	apoptosis	apoptosis	NN
cord-271972-qhr6iir6	261	23	to	to	TO
cord-271972-qhr6iir6	261	24	enhance	enhance	VB
cord-271972-qhr6iir6	261	25	viral	viral	JJ
cord-271972-qhr6iir6	261	26	release	release	NN
cord-271972-qhr6iir6	261	27	and	and	CC
cord-271972-qhr6iir6	261	28	spread	spread	VB
cord-271972-qhr6iir6	261	29	.	.	.
cord-271972-qhr6iir6	262	1	Mammalian	mammalian	JJ
cord-271972-qhr6iir6	262	2	reoviruses	reovirus	NNS
cord-271972-qhr6iir6	262	3	may	may	MD
cord-271972-qhr6iir6	262	4	subvert	subvert	VB
cord-271972-qhr6iir6	262	5	the	the	DT
cord-271972-qhr6iir6	262	6	host	host	NN
cord-271972-qhr6iir6	262	7	shutoff	shutoff	NN
cord-271972-qhr6iir6	262	8	activity	activity	NN
cord-271972-qhr6iir6	262	9	of	of	IN
cord-271972-qhr6iir6	262	10	RNase	RNase	NNP
cord-271972-qhr6iir6	262	11	L	L	NNP
cord-271972-qhr6iir6	262	12	to	to	TO
cord-271972-qhr6iir6	262	13	dispose	dispose	VB
cord-271972-qhr6iir6	262	14	of	of	IN
cord-271972-qhr6iir6	262	15	cellular	cellular	NN
cord-271972-qhr6iir6	262	16	mRNAs	mrna	NNS
cord-271972-qhr6iir6	262	17	and	and	CC
cord-271972-qhr6iir6	262	18	clear	clear	VB
cord-271972-qhr6iir6	262	19	the	the	DT
cord-271972-qhr6iir6	262	20	gene	gene	NN
cord-271972-qhr6iir6	262	21	expression	expression	NN
cord-271972-qhr6iir6	262	22	machinery	machinery	NN
cord-271972-qhr6iir6	262	23	for	for	IN
cord-271972-qhr6iir6	262	24	viral	viral	JJ
cord-271972-qhr6iir6	262	25	use	use	NN
cord-271972-qhr6iir6	262	26	.	.	.
cord-271972-qhr6iir6	263	1	90	90	CD
cord-271972-qhr6iir6	263	2	Replication	replication	NN
cord-271972-qhr6iir6	263	3	of	of	IN
cord-271972-qhr6iir6	263	4	both	both	CC
cord-271972-qhr6iir6	263	5	the	the	DT
cord-271972-qhr6iir6	263	6	Jones	Jones	NNP
cord-271972-qhr6iir6	263	7	and	and	CC
cord-271972-qhr6iir6	263	8	Dearing	Dearing	NNP
cord-271972-qhr6iir6	263	9	reovirus	reovirus	NN
cord-271972-qhr6iir6	263	10	strains	strain	NNS
cord-271972-qhr6iir6	263	11	was	be	VBD
cord-271972-qhr6iir6	263	12	reduced	reduce	VBN
cord-271972-qhr6iir6	263	13	by	by	IN
cord-271972-qhr6iir6	263	14	∼1	∼1	NNS
cord-271972-qhr6iir6	263	15	log	log	VBP
cord-271972-qhr6iir6	263	16	in	in	IN
cord-271972-qhr6iir6	263	17	RNase	RNase	NNP
cord-271972-qhr6iir6	263	18	L	l	NN
cord-271972-qhr6iir6	263	19	knockout	knockout	NN
cord-271972-qhr6iir6	263	20	relative	relative	NN
cord-271972-qhr6iir6	263	21	to	to	IN
cord-271972-qhr6iir6	263	22	wild	wild	JJ
cord-271972-qhr6iir6	263	23	-	-	HYPH
cord-271972-qhr6iir6	263	24	type	type	NN
cord-271972-qhr6iir6	263	25	mouse	mouse	NN
cord-271972-qhr6iir6	263	26	embryo	embryo	NN
cord-271972-qhr6iir6	263	27	fibroblasts	fibroblast	NNS
cord-271972-qhr6iir6	263	28	,	,	,
cord-271972-qhr6iir6	263	29	supporting	support	VBG
cord-271972-qhr6iir6	263	30	the	the	DT
cord-271972-qhr6iir6	263	31	idea	idea	NN
cord-271972-qhr6iir6	263	32	that	that	IN
cord-271972-qhr6iir6	263	33	the	the	DT
cord-271972-qhr6iir6	263	34	virus	virus	NN
cord-271972-qhr6iir6	263	35	partially	partially	RB
cord-271972-qhr6iir6	263	36	co	co	VBD
cord-271972-qhr6iir6	263	37	-	-	NN
cord-271972-qhr6iir6	263	38	opts	opt	VBZ
cord-271972-qhr6iir6	263	39	this	this	DT
cord-271972-qhr6iir6	263	40	pathway	pathway	NN
cord-271972-qhr6iir6	263	41	to	to	TO
cord-271972-qhr6iir6	263	42	facilitate	facilitate	VB
cord-271972-qhr6iir6	263	43	infection	infection	NN
cord-271972-qhr6iir6	263	44	.	.	.
cord-271972-qhr6iir6	264	1	90	90	CD
cord-271972-qhr6iir6	265	1	Interestingly	interestingly	RB
cord-271972-qhr6iir6	265	2	,	,	,
cord-271972-qhr6iir6	265	3	minimal	minimal	JJ
cord-271972-qhr6iir6	265	4	degradation	degradation	NN
cord-271972-qhr6iir6	265	5	of	of	IN
cord-271972-qhr6iir6	265	6	rRNAs	rrna	NNS
cord-271972-qhr6iir6	265	7	was	be	VBD
cord-271972-qhr6iir6	265	8	observed	observe	VBN
cord-271972-qhr6iir6	265	9	,	,	,
cord-271972-qhr6iir6	265	10	suggesting	suggest	VBG
cord-271972-qhr6iir6	265	11	that	that	IN
cord-271972-qhr6iir6	265	12	RNase	RNase	NNP
cord-271972-qhr6iir6	265	13	L	L	NNP
cord-271972-qhr6iir6	265	14	may	may	MD
cord-271972-qhr6iir6	265	15	not	not	RB
cord-271972-qhr6iir6	265	16	act	act	VB
cord-271972-qhr6iir6	265	17	indiscriminately	indiscriminately	RB
cord-271972-qhr6iir6	265	18	as	as	RB
cord-271972-qhr6iir6	265	19	originally	originally	RB
cord-271972-qhr6iir6	265	20	thought	think	VBN
cord-271972-qhr6iir6	265	21	,	,	,
cord-271972-qhr6iir6	265	22	but	but	CC
cord-271972-qhr6iir6	265	23	rather	rather	RB
cord-271972-qhr6iir6	265	24	target	target	VB
cord-271972-qhr6iir6	265	25	specific	specific	JJ
cord-271972-qhr6iir6	265	26	sequences	sequence	NNS
cord-271972-qhr6iir6	265	27	.	.	.
cord-271972-qhr6iir6	266	1	[	[	-LRB-
cord-271972-qhr6iir6	266	2	91	91	CD
cord-271972-qhr6iir6	266	3	]	]	-RRB-
cord-271972-qhr6iir6	266	4	[	[	-LRB-
cord-271972-qhr6iir6	266	5	92	92	CD
cord-271972-qhr6iir6	266	6	]	]	-RRB-
cord-271972-qhr6iir6	267	1	[	[	-LRB-
cord-271972-qhr6iir6	267	2	93	93	CD
cord-271972-qhr6iir6	267	3	]	]	-RRB-
cord-271972-qhr6iir6	268	1	The	the	DT
cord-271972-qhr6iir6	268	2	mechanism	mechanism	NN
cord-271972-qhr6iir6	268	3	of	of	IN
cord-271972-qhr6iir6	268	4	viral	viral	JJ
cord-271972-qhr6iir6	268	5	escape	escape	NN
cord-271972-qhr6iir6	268	6	from	from	IN
cord-271972-qhr6iir6	268	7	these	these	DT
cord-271972-qhr6iir6	268	8	pathways	pathway	NNS
cord-271972-qhr6iir6	268	9	remains	remain	VBZ
cord-271972-qhr6iir6	268	10	unknown	unknown	JJ
cord-271972-qhr6iir6	268	11	,	,	,
cord-271972-qhr6iir6	268	12	although	although	IN
cord-271972-qhr6iir6	268	13	the	the	DT
cord-271972-qhr6iir6	268	14	reovirus	reovirus	NNP
cord-271972-qhr6iir6	268	15	σ	σ	NNP
cord-271972-qhr6iir6	268	16	3	3	CD
cord-271972-qhr6iir6	268	17	protein	protein	NN
cord-271972-qhr6iir6	268	18	has	have	VBZ
cord-271972-qhr6iir6	268	19	been	be	VBN
cord-271972-qhr6iir6	268	20	proposed	propose	VBN
cord-271972-qhr6iir6	268	21	to	to	TO
cord-271972-qhr6iir6	268	22	coat	coat	VB
cord-271972-qhr6iir6	268	23	viral	viral	JJ
cord-271972-qhr6iir6	268	24	dsRNAs	dsRNAs	NNP
cord-271972-qhr6iir6	268	25	,	,	,
cord-271972-qhr6iir6	268	26	thereby	thereby	RB
cord-271972-qhr6iir6	268	27	selectively	selectively	RB
cord-271972-qhr6iir6	268	28	inhibiting	inhibit	VBG
cord-271972-qhr6iir6	268	29	RNase	RNase	NNP
cord-271972-qhr6iir6	268	30	L	L	NNP
cord-271972-qhr6iir6	268	31	activation	activation	NN
cord-271972-qhr6iir6	268	32	in	in	IN
cord-271972-qhr6iir6	268	33	cytoplasmic	cytoplasmic	JJ
cord-271972-qhr6iir6	268	34	locales	locale	NNS
cord-271972-qhr6iir6	268	35	where	where	WRB
cord-271972-qhr6iir6	268	36	viral	viral	JJ
cord-271972-qhr6iir6	268	37	RNA	RNA	NNP
cord-271972-qhr6iir6	268	38	replication	replication	NN
cord-271972-qhr6iir6	268	39	occurs	occur	VBZ
cord-271972-qhr6iir6	268	40	,	,	,
cord-271972-qhr6iir6	268	41	i.e.	i.e.	FW
cord-271972-qhr6iir6	268	42	,	,	,
cord-271972-qhr6iir6	268	43	'	'	''
cord-271972-qhr6iir6	268	44	replication	replication	NN
cord-271972-qhr6iir6	268	45	factories	factory	NNS
cord-271972-qhr6iir6	268	46	'	'	''
cord-271972-qhr6iir6	268	47	.	.	.
cord-271972-qhr6iir6	269	1	94	94	CD
cord-271972-qhr6iir6	270	1	However	however	RB
cord-271972-qhr6iir6	270	2	,	,	,
cord-271972-qhr6iir6	270	3	it	-PRON-	PRP
cord-271972-qhr6iir6	270	4	should	should	MD
cord-271972-qhr6iir6	270	5	be	be	VB
cord-271972-qhr6iir6	270	6	noted	note	VBN
cord-271972-qhr6iir6	270	7	that	that	IN
cord-271972-qhr6iir6	270	8	the	the	DT
cord-271972-qhr6iir6	270	9	results	result	NNS
cord-271972-qhr6iir6	270	10	mentioned	mention	VBN
cord-271972-qhr6iir6	270	11	above	above	IN
cord-271972-qhr6iir6	270	12	contrast	contrast	NN
cord-271972-qhr6iir6	270	13	with	with	IN
cord-271972-qhr6iir6	270	14	earlier	early	JJR
cord-271972-qhr6iir6	270	15	findings	finding	NNS
cord-271972-qhr6iir6	270	16	implicating	implicate	VBG
cord-271972-qhr6iir6	270	17	RNase	RNase	NNP
cord-271972-qhr6iir6	270	18	L	L	NNP
cord-271972-qhr6iir6	270	19	in	in	IN
cord-271972-qhr6iir6	270	20	restricting	restrict	VBG
cord-271972-qhr6iir6	270	21	reovirus	reovirus	NN
cord-271972-qhr6iir6	270	22	replication	replication	NN
cord-271972-qhr6iir6	270	23	,	,	,
cord-271972-qhr6iir6	270	24	which	which	WDT
cord-271972-qhr6iir6	270	25	may	may	MD
cord-271972-qhr6iir6	270	26	be	be	VB
cord-271972-qhr6iir6	270	27	due	due	JJ
cord-271972-qhr6iir6	270	28	to	to	IN
cord-271972-qhr6iir6	270	29	the	the	DT
cord-271972-qhr6iir6	270	30	use	use	NN
cord-271972-qhr6iir6	270	31	of	of	IN
cord-271972-qhr6iir6	270	32	different	different	JJ
cord-271972-qhr6iir6	270	33	cell	cell	NN
cord-271972-qhr6iir6	270	34	types	type	NNS
cord-271972-qhr6iir6	270	35	in	in	IN
cord-271972-qhr6iir6	270	36	these	these	DT
cord-271972-qhr6iir6	270	37	studies	study	NNS
cord-271972-qhr6iir6	270	38	.	.	.
cord-271972-qhr6iir6	271	1	95	95	CD
cord-271972-qhr6iir6	271	2	,	,	,
cord-271972-qhr6iir6	271	3	96	96	CD
cord-271972-qhr6iir6	271	4	 	 	_SP
cord-271972-qhr6iir6	272	1	In	in	IN
cord-271972-qhr6iir6	272	2	addition	addition	NN
cord-271972-qhr6iir6	272	3	to	to	IN
cord-271972-qhr6iir6	272	4	the	the	DT
cord-271972-qhr6iir6	272	5	examples	example	NNS
cord-271972-qhr6iir6	272	6	highlighted	highlight	VBN
cord-271972-qhr6iir6	272	7	herein	herein	RB
cord-271972-qhr6iir6	272	8	,	,	,
cord-271972-qhr6iir6	272	9	in	in	IN
cord-271972-qhr6iir6	272	10	many	many	JJ
cord-271972-qhr6iir6	272	11	other	other	JJ
cord-271972-qhr6iir6	272	12	cases	case	NNS
cord-271972-qhr6iir6	272	13	viral	viral	JJ
cord-271972-qhr6iir6	272	14	infection	infection	NN
cord-271972-qhr6iir6	272	15	presumably	presumably	RB
cord-271972-qhr6iir6	272	16	leads	lead	VBZ
cord-271972-qhr6iir6	272	17	to	to	IN
cord-271972-qhr6iir6	272	18	robust	robust	JJ
cord-271972-qhr6iir6	272	19	engagement	engagement	NN
cord-271972-qhr6iir6	272	20	of	of	IN
cord-271972-qhr6iir6	272	21	cellular	cellular	JJ
cord-271972-qhr6iir6	272	22	mRNA	mrna	NN
cord-271972-qhr6iir6	272	23	turnover	turnover	NN
cord-271972-qhr6iir6	272	24	machinery	machinery	NN
cord-271972-qhr6iir6	272	25	.	.	.
cord-271972-qhr6iir6	273	1	For	for	IN
cord-271972-qhr6iir6	273	2	example	example	NN
cord-271972-qhr6iir6	273	3	,	,	,
cord-271972-qhr6iir6	273	4	several	several	JJ
cord-271972-qhr6iir6	273	5	viruses	virus	NNS
cord-271972-qhr6iir6	273	6	remove	remove	VBP
cord-271972-qhr6iir6	273	7	the	the	DT
cord-271972-qhr6iir6	273	8	7-methylguanosine	7-methylguanosine	CD
cord-271972-qhr6iir6	273	9	caps	cap	NNS
cord-271972-qhr6iir6	273	10	from	from	IN
cord-271972-qhr6iir6	273	11	cellular	cellular	JJ
cord-271972-qhr6iir6	273	12	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	273	13	,	,	,
cord-271972-qhr6iir6	273	14	prevent	prevent	VB
cord-271972-qhr6iir6	273	15	appropriate	appropriate	JJ
cord-271972-qhr6iir6	273	16	cellular	cellular	JJ
cord-271972-qhr6iir6	273	17	mRNA	mrna	NN
cord-271972-qhr6iir6	273	18	splicing	splicing	NN
cord-271972-qhr6iir6	273	19	,	,	,
cord-271972-qhr6iir6	273	20	3	3	CD
cord-271972-qhr6iir6	273	21	processing	processing	NN
cord-271972-qhr6iir6	273	22	,	,	,
cord-271972-qhr6iir6	273	23	or	or	CC
cord-271972-qhr6iir6	273	24	polyadenylation	polyadenylation	NN
cord-271972-qhr6iir6	273	25	,	,	,
cord-271972-qhr6iir6	273	26	or	or	CC
cord-271972-qhr6iir6	273	27	directly	directly	RB
cord-271972-qhr6iir6	273	28	cleave	cleave	VB
cord-271972-qhr6iir6	273	29	cellular	cellular	JJ
cord-271972-qhr6iir6	273	30	messages	message	NNS
cord-271972-qhr6iir6	273	31	.	.	.
cord-271972-qhr6iir6	274	1	27	27	CD
cord-271972-qhr6iir6	274	2	,	,	,
cord-271972-qhr6iir6	274	3	46	46	CD
cord-271972-qhr6iir6	274	4	,	,	,
cord-271972-qhr6iir6	274	5	[	[	-LRB-
cord-271972-qhr6iir6	274	6	97	97	CD
cord-271972-qhr6iir6	274	7	]	]	-RRB-
cord-271972-qhr6iir6	274	8	[	[	-LRB-
cord-271972-qhr6iir6	274	9	98	98	CD
cord-271972-qhr6iir6	274	10	]	]	-RRB-
cord-271972-qhr6iir6	274	11	[	[	-LRB-
cord-271972-qhr6iir6	274	12	99	99	CD
cord-271972-qhr6iir6	274	13	]	]	-RRB-
cord-271972-qhr6iir6	275	1	[	[	-LRB-
cord-271972-qhr6iir6	275	2	100	100	CD
cord-271972-qhr6iir6	275	3	]	]	-RRB-
cord-271972-qhr6iir6	276	1	Presumably	presumably	RB
cord-271972-qhr6iir6	276	2	these	these	DT
cord-271972-qhr6iir6	276	3	events	event	NNS
cord-271972-qhr6iir6	276	4	lead	lead	VBP
cord-271972-qhr6iir6	276	5	to	to	IN
cord-271972-qhr6iir6	276	6	destruction	destruction	NN
cord-271972-qhr6iir6	276	7	of	of	IN
cord-271972-qhr6iir6	276	8	the	the	DT
cord-271972-qhr6iir6	276	9	impaired	impaired	JJ
cord-271972-qhr6iir6	276	10	cellular	cellular	JJ
cord-271972-qhr6iir6	276	11	transcripts	transcript	NNS
cord-271972-qhr6iir6	276	12	through	through	IN
cord-271972-qhr6iir6	276	13	both	both	CC
cord-271972-qhr6iir6	276	14	basal	basal	NN
cord-271972-qhr6iir6	276	15	and	and	CC
cord-271972-qhr6iir6	276	16	quality	quality	NN
cord-271972-qhr6iir6	276	17	control	control	NN
cord-271972-qhr6iir6	276	18	machinery	machinery	NN
cord-271972-qhr6iir6	276	19	operating	operate	VBG
cord-271972-qhr6iir6	276	20	in	in	IN
cord-271972-qhr6iir6	276	21	the	the	DT
cord-271972-qhr6iir6	276	22	nucleus	nucleus	NN
cord-271972-qhr6iir6	276	23	and	and	CC
cord-271972-qhr6iir6	276	24	in	in	IN
cord-271972-qhr6iir6	276	25	the	the	DT
cord-271972-qhr6iir6	276	26	cytoplasm	cytoplasm	NN
cord-271972-qhr6iir6	276	27	.	.	.
cord-271972-qhr6iir6	277	1	Such	such	JJ
cord-271972-qhr6iir6	277	2	elevated	elevated	JJ
cord-271972-qhr6iir6	277	3	global	global	JJ
cord-271972-qhr6iir6	277	4	RNA	RNA	NNP
cord-271972-qhr6iir6	277	5	degradation	degradation	NN
cord-271972-qhr6iir6	277	6	may	may	MD
cord-271972-qhr6iir6	277	7	overload	overload	VB
cord-271972-qhr6iir6	277	8	the	the	DT
cord-271972-qhr6iir6	277	9	RNA	RNA	NNP
cord-271972-qhr6iir6	277	10	turnover	turnover	NN
cord-271972-qhr6iir6	277	11	machinery	machinery	NN
cord-271972-qhr6iir6	277	12	,	,	,
cord-271972-qhr6iir6	277	13	potentially	potentially	RB
cord-271972-qhr6iir6	277	14	indirectly	indirectly	RB
cord-271972-qhr6iir6	277	15	stabilizing	stabilize	VBG
cord-271972-qhr6iir6	277	16	viral	viral	JJ
cord-271972-qhr6iir6	277	17	transcripts	transcript	NNS
cord-271972-qhr6iir6	277	18	.	.	.
cord-271972-qhr6iir6	278	1	Aside	aside	RB
cord-271972-qhr6iir6	278	2	from	from	IN
cord-271972-qhr6iir6	278	3	affecting	affect	VBG
cord-271972-qhr6iir6	278	4	global	global	JJ
cord-271972-qhr6iir6	278	5	RNA	RNA	NNP
cord-271972-qhr6iir6	278	6	levels	level	NNS
cord-271972-qhr6iir6	278	7	,	,	,
cord-271972-qhr6iir6	278	8	viruses	virus	NNS
cord-271972-qhr6iir6	278	9	can	can	MD
cord-271972-qhr6iir6	278	10	also	also	RB
cord-271972-qhr6iir6	278	11	selectively	selectively	RB
cord-271972-qhr6iir6	278	12	alter	alter	VB
cord-271972-qhr6iir6	278	13	the	the	DT
cord-271972-qhr6iir6	278	14	stability	stability	NN
cord-271972-qhr6iir6	278	15	of	of	IN
cord-271972-qhr6iir6	278	16	specific	specific	JJ
cord-271972-qhr6iir6	278	17	messages	message	NNS
cord-271972-qhr6iir6	278	18	through	through	IN
cord-271972-qhr6iir6	278	19	the	the	DT
cord-271972-qhr6iir6	278	20	induction	induction	NN
cord-271972-qhr6iir6	278	21	of	of	IN
cord-271972-qhr6iir6	278	22	cellular	cellular	JJ
cord-271972-qhr6iir6	278	23	signaling	signal	VBG
cord-271972-qhr6iir6	278	24	pathways	pathway	NNS
cord-271972-qhr6iir6	278	25	.	.	.
cord-271972-qhr6iir6	279	1	For	for	IN
cord-271972-qhr6iir6	279	2	example	example	NN
cord-271972-qhr6iir6	279	3	,	,	,
cord-271972-qhr6iir6	279	4	the	the	DT
cord-271972-qhr6iir6	279	5	activation	activation	NN
cord-271972-qhr6iir6	279	6	of	of	IN
cord-271972-qhr6iir6	279	7	the	the	DT
cord-271972-qhr6iir6	279	8	MK2	MK2	NNP
cord-271972-qhr6iir6	279	9	/	/	SYM
cord-271972-qhr6iir6	279	10	p38	p38	CD
cord-271972-qhr6iir6	279	11	pathway	pathway	NN
cord-271972-qhr6iir6	279	12	by	by	IN
cord-271972-qhr6iir6	279	13	the	the	DT
cord-271972-qhr6iir6	279	14	kaposin	kaposin	NNP
cord-271972-qhr6iir6	279	15	B	B	NNP
cord-271972-qhr6iir6	279	16	protein	protein	NN
cord-271972-qhr6iir6	279	17	of	of	IN
cord-271972-qhr6iir6	279	18	KSHV	KSHV	NNP
cord-271972-qhr6iir6	279	19	leads	lead	VBZ
cord-271972-qhr6iir6	279	20	to	to	IN
cord-271972-qhr6iir6	279	21	stabilization	stabilization	NN
cord-271972-qhr6iir6	279	22	of	of	IN
cord-271972-qhr6iir6	279	23	cytokine	cytokine	NN
cord-271972-qhr6iir6	279	24	mRNAs	mrna	VBD
cord-271972-qhr6iir6	279	25	bearing	bear	VBG
cord-271972-qhr6iir6	279	26	AU	AU	NNP
cord-271972-qhr6iir6	279	27	-	-	HYPH
cord-271972-qhr6iir6	279	28	rich	rich	JJ
cord-271972-qhr6iir6	279	29	elements	element	NNS
cord-271972-qhr6iir6	279	30	in	in	IN
cord-271972-qhr6iir6	279	31	their	-PRON-	PRP$
cord-271972-qhr6iir6	279	32	3	3	CD
cord-271972-qhr6iir6	279	33	UTRs	utr	NNS
cord-271972-qhr6iir6	279	34	.	.	.
cord-271972-qhr6iir6	280	1	101	101	CD
cord-271972-qhr6iir6	281	1	In	in	IN
cord-271972-qhr6iir6	281	2	these	these	DT
cord-271972-qhr6iir6	281	3	cases	case	NNS
cord-271972-qhr6iir6	281	4	,	,	,
cord-271972-qhr6iir6	281	5	viral	viral	JJ
cord-271972-qhr6iir6	281	6	manipulation	manipulation	NN
cord-271972-qhr6iir6	281	7	of	of	IN
cord-271972-qhr6iir6	281	8	select	select	JJ
cord-271972-qhr6iir6	281	9	transcript	transcript	NN
cord-271972-qhr6iir6	281	10	stability	stability	NN
cord-271972-qhr6iir6	281	11	likely	likely	RB
cord-271972-qhr6iir6	281	12	has	have	VBZ
cord-271972-qhr6iir6	281	13	important	important	JJ
cord-271972-qhr6iir6	281	14	consequences	consequence	NNS
cord-271972-qhr6iir6	281	15	for	for	IN
cord-271972-qhr6iir6	281	16	overall	overall	JJ
cord-271972-qhr6iir6	281	17	pathogenesis	pathogenesis	NN
cord-271972-qhr6iir6	281	18	.	.	.
cord-271972-qhr6iir6	282	1	Our	-PRON-	PRP$
cord-271972-qhr6iir6	282	2	understanding	understanding	NN
cord-271972-qhr6iir6	282	3	of	of	IN
cord-271972-qhr6iir6	282	4	the	the	DT
cord-271972-qhr6iir6	282	5	multitude	multitude	NN
cord-271972-qhr6iir6	282	6	of	of	IN
cord-271972-qhr6iir6	282	7	ways	way	NNS
cord-271972-qhr6iir6	282	8	in	in	IN
cord-271972-qhr6iir6	282	9	which	which	WDT
cord-271972-qhr6iir6	282	10	viruses	virus	NNS
cord-271972-qhr6iir6	282	11	either	either	CC
cord-271972-qhr6iir6	282	12	commandeer	commandeer	VBP
cord-271972-qhr6iir6	282	13	or	or	CC
cord-271972-qhr6iir6	282	14	are	be	VBP
cord-271972-qhr6iir6	282	15	controlled	control	VBN
cord-271972-qhr6iir6	282	16	by	by	IN
cord-271972-qhr6iir6	282	17	cellular	cellular	JJ
cord-271972-qhr6iir6	282	18	mRNA	mRNA	NNP
cord-271972-qhr6iir6	282	19	turnover	turnover	NN
cord-271972-qhr6iir6	282	20	pathways	pathway	NNS
cord-271972-qhr6iir6	282	21	is	be	VBZ
cord-271972-qhr6iir6	282	22	constantly	constantly	RB
cord-271972-qhr6iir6	282	23	evolving	evolve	VBG
cord-271972-qhr6iir6	282	24	,	,	,
cord-271972-qhr6iir6	282	25	and	and	CC
cord-271972-qhr6iir6	282	26	far	far	RB
cord-271972-qhr6iir6	282	27	from	from	IN
cord-271972-qhr6iir6	282	28	complete	complete	JJ
cord-271972-qhr6iir6	282	29	.	.	.
cord-271972-qhr6iir6	283	1	Moreover	moreover	RB
cord-271972-qhr6iir6	283	2	,	,	,
cord-271972-qhr6iir6	283	3	many	many	JJ
cord-271972-qhr6iir6	283	4	of	of	IN
cord-271972-qhr6iir6	283	5	the	the	DT
cord-271972-qhr6iir6	283	6	pathways	pathway	NNS
cord-271972-qhr6iir6	283	7	governing	govern	VBG
cord-271972-qhr6iir6	283	8	cellular	cellular	JJ
cord-271972-qhr6iir6	283	9	mRNA	mrna	NN
cord-271972-qhr6iir6	283	10	decay	decay	NN
cord-271972-qhr6iir6	283	11	remain	remain	VBP
cord-271972-qhr6iir6	283	12	incompletely	incompletely	RB
cord-271972-qhr6iir6	283	13	understood	understand	VBN
cord-271972-qhr6iir6	283	14	even	even	RB
cord-271972-qhr6iir6	283	15	in	in	IN
cord-271972-qhr6iir6	283	16	uninfected	uninfected	JJ
cord-271972-qhr6iir6	283	17	cells	cell	NNS
cord-271972-qhr6iir6	283	18	,	,	,
cord-271972-qhr6iir6	283	19	and	and	CC
cord-271972-qhr6iir6	283	20	new	new	JJ
cord-271972-qhr6iir6	283	21	components	component	NNS
cord-271972-qhr6iir6	283	22	and	and	CC
cord-271972-qhr6iir6	283	23	mechanisms	mechanism	NNS
cord-271972-qhr6iir6	283	24	are	be	VBP
cord-271972-qhr6iir6	283	25	constantly	constantly	RB
cord-271972-qhr6iir6	283	26	described	describe	VBN
cord-271972-qhr6iir6	283	27	.	.	.
cord-271972-qhr6iir6	284	1	Thus	thus	RB
cord-271972-qhr6iir6	284	2	,	,	,
cord-271972-qhr6iir6	284	3	as	as	IN
cord-271972-qhr6iir6	284	4	in	in	IN
cord-271972-qhr6iir6	284	5	many	many	JJ
cord-271972-qhr6iir6	284	6	other	other	JJ
cord-271972-qhr6iir6	284	7	fields	field	NNS
cord-271972-qhr6iir6	284	8	of	of	IN
cord-271972-qhr6iir6	284	9	biology	biology	NN
cord-271972-qhr6iir6	284	10	,	,	,
cord-271972-qhr6iir6	284	11	viruses	virus	NNS
cord-271972-qhr6iir6	284	12	will	will	MD
cord-271972-qhr6iir6	284	13	continue	continue	VB
cord-271972-qhr6iir6	284	14	to	to	TO
cord-271972-qhr6iir6	284	15	be	be	VB
cord-271972-qhr6iir6	284	16	invaluable	invaluable	JJ
cord-271972-qhr6iir6	284	17	tools	tool	NNS
cord-271972-qhr6iir6	284	18	for	for	IN
cord-271972-qhr6iir6	284	19	revealing	reveal	VBG
cord-271972-qhr6iir6	284	20	key	key	JJ
cord-271972-qhr6iir6	284	21	modulators	modulator	NNS
cord-271972-qhr6iir6	284	22	of	of	IN
cord-271972-qhr6iir6	284	23	mRNA	mrna	NN
cord-271972-qhr6iir6	284	24	stability	stability	NN
cord-271972-qhr6iir6	284	25	and	and	CC
cord-271972-qhr6iir6	284	26	destruction	destruction	NN
cord-271972-qhr6iir6	284	27	both	both	DT
cord-271972-qhr6iir6	284	28	in	in	IN
cord-271972-qhr6iir6	284	29	normal	normal	JJ
cord-271972-qhr6iir6	284	30	and	and	CC
cord-271972-qhr6iir6	284	31	pathogenic	pathogenic	JJ
cord-271972-qhr6iir6	284	32	states	state	NNS
cord-271972-qhr6iir6	284	33	.	.	.
cord-271972-qhr6iir6	285	1	RNA	RNA	NNP
cord-271972-qhr6iir6	285	2	quality	quality	NN
cord-271972-qhr6iir6	285	3	control	control	NN
cord-271972-qhr6iir6	285	4	in	in	IN
cord-271972-qhr6iir6	285	5	eukaryotes	eukaryote	NNS
cord-271972-qhr6iir6	286	1	Multifunctional	Multifunctional	NNP
cord-271972-qhr6iir6	286	2	deadenylase	deadenylase	NNP
cord-271972-qhr6iir6	286	3	complexes	complex	NNS
cord-271972-qhr6iir6	286	4	diversify	diversify	VBP
cord-271972-qhr6iir6	286	5	mRNA	mrna	NN
cord-271972-qhr6iir6	287	1	control	control	NNP
cord-271972-qhr6iir6	288	1	The	the	DT
cord-271972-qhr6iir6	288	2	enzymes	enzyme	NNS
cord-271972-qhr6iir6	288	3	and	and	CC
cord-271972-qhr6iir6	288	4	control	control	NN
cord-271972-qhr6iir6	288	5	of	of	IN
cord-271972-qhr6iir6	288	6	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	288	7	mRNA	mRNA	NNP
cord-271972-qhr6iir6	288	8	turnover	turnover	NN
cord-271972-qhr6iir6	289	1	The	the	DT
cord-271972-qhr6iir6	289	2	3	3	CD
cord-271972-qhr6iir6	289	3	untranslated	untranslated	JJ
cord-271972-qhr6iir6	289	4	region	region	NN
cord-271972-qhr6iir6	289	5	of	of	IN
cord-271972-qhr6iir6	289	6	sindbis	sindbis	NNP
cord-271972-qhr6iir6	289	7	virus	virus	NN
cord-271972-qhr6iir6	289	8	represses	repress	VBZ
cord-271972-qhr6iir6	289	9	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	289	10	of	of	IN
cord-271972-qhr6iir6	289	11	viral	viral	JJ
cord-271972-qhr6iir6	289	12	transcripts	transcript	NNS
cord-271972-qhr6iir6	289	13	in	in	IN
cord-271972-qhr6iir6	289	14	mosquito	mosquito	NN
cord-271972-qhr6iir6	289	15	and	and	CC
cord-271972-qhr6iir6	289	16	Mammalian	mammalian	JJ
cord-271972-qhr6iir6	289	17	cells	cell	NNS
cord-271972-qhr6iir6	290	1	A	a	DT
cord-271972-qhr6iir6	290	2	Kaposi	Kaposi	NNP
cord-271972-qhr6iir6	290	3	's	's	POS
cord-271972-qhr6iir6	290	4	sarcoma	sarcoma	NN
cord-271972-qhr6iir6	290	5	virus	virus	NN
cord-271972-qhr6iir6	290	6	RNA	rna	NN
cord-271972-qhr6iir6	290	7	element	element	NN
cord-271972-qhr6iir6	290	8	that	that	WDT
cord-271972-qhr6iir6	290	9	increases	increase	VBZ
cord-271972-qhr6iir6	290	10	the	the	DT
cord-271972-qhr6iir6	290	11	nuclear	nuclear	JJ
cord-271972-qhr6iir6	290	12	abundance	abundance	NN
cord-271972-qhr6iir6	290	13	of	of	IN
cord-271972-qhr6iir6	290	14	intronless	intronless	NN
cord-271972-qhr6iir6	290	15	transcripts	transcript	NNS
cord-271972-qhr6iir6	290	16	Identification	Identification	NNP
cord-271972-qhr6iir6	290	17	of	of	IN
cord-271972-qhr6iir6	290	18	a	a	DT
cord-271972-qhr6iir6	290	19	rapid	rapid	JJ
cord-271972-qhr6iir6	290	20	mammalian	mammalian	JJ
cord-271972-qhr6iir6	290	21	deadenylationdependent	deadenylationdependent	NN
cord-271972-qhr6iir6	290	22	decay	decay	NN
cord-271972-qhr6iir6	290	23	pathway	pathway	NN
cord-271972-qhr6iir6	290	24	and	and	CC
cord-271972-qhr6iir6	290	25	its	-PRON-	PRP$
cord-271972-qhr6iir6	290	26	inhibition	inhibition	NN
cord-271972-qhr6iir6	290	27	by	by	IN
cord-271972-qhr6iir6	290	28	a	a	DT
cord-271972-qhr6iir6	290	29	viral	viral	JJ
cord-271972-qhr6iir6	290	30	RNA	RNA	NNP
cord-271972-qhr6iir6	290	31	element	element	NN
cord-271972-qhr6iir6	290	32	Mutational	Mutational	NNP
cord-271972-qhr6iir6	290	33	analysis	analysis	NN
cord-271972-qhr6iir6	290	34	of	of	IN
cord-271972-qhr6iir6	290	35	a	a	DT
cord-271972-qhr6iir6	290	36	viral	viral	JJ
cord-271972-qhr6iir6	290	37	RNA	rna	NN
cord-271972-qhr6iir6	290	38	element	element	NN
cord-271972-qhr6iir6	290	39	that	that	WDT
cord-271972-qhr6iir6	290	40	counteracts	counteract	VBZ
cord-271972-qhr6iir6	290	41	rapid	rapid	JJ
cord-271972-qhr6iir6	290	42	RNA	RNA	NNP
cord-271972-qhr6iir6	290	43	decay	decay	NN
cord-271972-qhr6iir6	290	44	by	by	IN
cord-271972-qhr6iir6	290	45	interaction	interaction	NN
cord-271972-qhr6iir6	290	46	with	with	IN
cord-271972-qhr6iir6	290	47	the	the	DT
cord-271972-qhr6iir6	290	48	polyadenylate	polyadenylate	NN
cord-271972-qhr6iir6	290	49	tail	tail	NN
cord-271972-qhr6iir6	291	1	An	an	DT
cord-271972-qhr6iir6	291	2	essential	essential	JJ
cord-271972-qhr6iir6	291	3	component	component	NN
cord-271972-qhr6iir6	291	4	of	of	IN
cord-271972-qhr6iir6	291	5	the	the	DT
cord-271972-qhr6iir6	291	6	decapping	decapping	NN
cord-271972-qhr6iir6	291	7	enzyme	enzyme	NN
cord-271972-qhr6iir6	291	8	required	require	VBN
cord-271972-qhr6iir6	291	9	for	for	IN
cord-271972-qhr6iir6	291	10	normal	normal	JJ
cord-271972-qhr6iir6	291	11	rates	rate	NNS
cord-271972-qhr6iir6	291	12	of	of	IN
cord-271972-qhr6iir6	291	13	mRNA	mrna	NN
cord-271972-qhr6iir6	291	14	turnover	turnover	NN
cord-271972-qhr6iir6	292	1	The	the	DT
cord-271972-qhr6iir6	292	2	DCP2	DCP2	NNP
cord-271972-qhr6iir6	292	3	protein	protein	NN
cord-271972-qhr6iir6	292	4	is	be	VBZ
cord-271972-qhr6iir6	292	5	required	require	VBN
cord-271972-qhr6iir6	292	6	for	for	IN
cord-271972-qhr6iir6	292	7	mRNA	mrna	NN
cord-271972-qhr6iir6	292	8	decapping	decappe	VBG
cord-271972-qhr6iir6	292	9	in	in	IN
cord-271972-qhr6iir6	292	10	Saccharomyces	Saccharomyces	NNP
cord-271972-qhr6iir6	292	11	cerevisiae	cerevisiae	NNS
cord-271972-qhr6iir6	292	12	and	and	CC
cord-271972-qhr6iir6	292	13	contains	contain	VBZ
cord-271972-qhr6iir6	292	14	a	a	DT
cord-271972-qhr6iir6	292	15	functional	functional	JJ
cord-271972-qhr6iir6	292	16	MutT	MutT	NNP
cord-271972-qhr6iir6	292	17	motif	motif	NN
cord-271972-qhr6iir6	292	18	Yeast	Yeast	NNP
cord-271972-qhr6iir6	292	19	Sm	Sm	NNP
cord-271972-qhr6iir6	292	20	-	-	HYPH
cord-271972-qhr6iir6	292	21	like	like	JJ
cord-271972-qhr6iir6	292	22	proteins	protein	NNS
cord-271972-qhr6iir6	292	23	function	function	VBP
cord-271972-qhr6iir6	292	24	in	in	IN
cord-271972-qhr6iir6	292	25	mRNA	mRNA	NNP
cord-271972-qhr6iir6	292	26	decapping	decapping	NN
cord-271972-qhr6iir6	292	27	and	and	CC
cord-271972-qhr6iir6	292	28	decay	decay	VB
cord-271972-qhr6iir6	293	1	Targeting	target	VBG
cord-271972-qhr6iir6	293	2	an	an	DT
cord-271972-qhr6iir6	293	3	mRNA	mrna	NN
cord-271972-qhr6iir6	293	4	for	for	IN
cord-271972-qhr6iir6	293	5	decapping	decapping	NN
cord-271972-qhr6iir6	293	6	:	:	:
cord-271972-qhr6iir6	293	7	displacement	displacement	NN
cord-271972-qhr6iir6	293	8	of	of	IN
cord-271972-qhr6iir6	293	9	translation	translation	NN
cord-271972-qhr6iir6	293	10	factors	factor	NNS
cord-271972-qhr6iir6	293	11	and	and	CC
cord-271972-qhr6iir6	293	12	association	association	NN
cord-271972-qhr6iir6	293	13	of	of	IN
cord-271972-qhr6iir6	293	14	the	the	DT
cord-271972-qhr6iir6	293	15	Lsm1p-7p	Lsm1p-7p	NNP
cord-271972-qhr6iir6	293	16	complex	complex	NN
cord-271972-qhr6iir6	293	17	on	on	IN
cord-271972-qhr6iir6	293	18	deadenylated	deadenylate	VBN
cord-271972-qhr6iir6	293	19	yeast	yeast	NN
cord-271972-qhr6iir6	294	1	mRNAs	mRNAs	.
cord-271972-qhr6iir6	295	1	The	the	DT
cord-271972-qhr6iir6	295	2	two	two	CD
cord-271972-qhr6iir6	295	3	proteins	protein	NNS
cord-271972-qhr6iir6	295	4	Pat1p	pat1p	JJ
cord-271972-qhr6iir6	295	5	(	(	-LRB-
cord-271972-qhr6iir6	295	6	Mrt1p	Mrt1p	NNP
cord-271972-qhr6iir6	295	7	)	)	-RRB-
cord-271972-qhr6iir6	295	8	and	and	CC
cord-271972-qhr6iir6	295	9	Spb8p	Spb8p	NNPS
cord-271972-qhr6iir6	295	10	interact	interact	VB
cord-271972-qhr6iir6	295	11	in	in	IN
cord-271972-qhr6iir6	295	12	vivo	vivo	NN
cord-271972-qhr6iir6	295	13	,	,	,
cord-271972-qhr6iir6	295	14	are	be	VBP
cord-271972-qhr6iir6	295	15	required	require	VBN
cord-271972-qhr6iir6	295	16	for	for	IN
cord-271972-qhr6iir6	295	17	mRNA	mRNA	NNP
cord-271972-qhr6iir6	295	18	decay	decay	NN
cord-271972-qhr6iir6	295	19	,	,	,
cord-271972-qhr6iir6	295	20	and	and	CC
cord-271972-qhr6iir6	295	21	are	be	VBP
cord-271972-qhr6iir6	295	22	functionally	functionally	RB
cord-271972-qhr6iir6	295	23	linked	link	VBN
cord-271972-qhr6iir6	295	24	to	to	IN
cord-271972-qhr6iir6	295	25	Pab1p	Pab1p	NNP
cord-271972-qhr6iir6	296	1	A	a	DT
cord-271972-qhr6iir6	296	2	Sm	sm	NN
cord-271972-qhr6iir6	296	3	-	-	HYPH
cord-271972-qhr6iir6	296	4	like	like	JJ
cord-271972-qhr6iir6	296	5	protein	protein	NN
cord-271972-qhr6iir6	296	6	complex	complex	NN
cord-271972-qhr6iir6	296	7	that	that	WDT
cord-271972-qhr6iir6	296	8	participates	participate	VBZ
cord-271972-qhr6iir6	296	9	in	in	IN
cord-271972-qhr6iir6	296	10	mRNA	mRNA	NNP
cord-271972-qhr6iir6	296	11	degradation	degradation	NN
cord-271972-qhr6iir6	297	1	The	the	DT
cord-271972-qhr6iir6	297	2	DEAD	dead	JJ
cord-271972-qhr6iir6	297	3	box	box	NN
cord-271972-qhr6iir6	297	4	helicase	helicase	NN
cord-271972-qhr6iir6	297	5	,	,	,
cord-271972-qhr6iir6	297	6	Dhh1p	Dhh1p	NNS
cord-271972-qhr6iir6	297	7	,	,	,
cord-271972-qhr6iir6	297	8	functions	function	NNS
cord-271972-qhr6iir6	297	9	in	in	IN
cord-271972-qhr6iir6	297	10	mRNA	mRNA	NNP
cord-271972-qhr6iir6	297	11	decapping	decapping	NNP
cord-271972-qhr6iir6	297	12	and	and	CC
cord-271972-qhr6iir6	297	13	interacts	interact	VBZ
cord-271972-qhr6iir6	297	14	with	with	IN
cord-271972-qhr6iir6	297	15	both	both	CC
cord-271972-qhr6iir6	297	16	the	the	DT
cord-271972-qhr6iir6	297	17	decapping	decapping	NN
cord-271972-qhr6iir6	297	18	and	and	CC
cord-271972-qhr6iir6	297	19	deadenylase	deadenylase	NNP
cord-271972-qhr6iir6	297	20	complexes	complex	NNS
cord-271972-qhr6iir6	297	21	Identification	identification	NN
cord-271972-qhr6iir6	297	22	and	and	CC
cord-271972-qhr6iir6	297	23	characterization	characterization	NN
cord-271972-qhr6iir6	297	24	of	of	IN
cord-271972-qhr6iir6	297	25	a	a	DT
cord-271972-qhr6iir6	297	26	host	host	NN
cord-271972-qhr6iir6	297	27	protein	protein	NN
cord-271972-qhr6iir6	297	28	required	require	VBN
cord-271972-qhr6iir6	297	29	for	for	IN
cord-271972-qhr6iir6	297	30	efficient	efficient	JJ
cord-271972-qhr6iir6	297	31	template	template	NN
cord-271972-qhr6iir6	297	32	selection	selection	NN
cord-271972-qhr6iir6	297	33	in	in	IN
cord-271972-qhr6iir6	297	34	viral	viral	JJ
cord-271972-qhr6iir6	297	35	RNA	RNA	NNP
cord-271972-qhr6iir6	297	36	replication	replication	NN
cord-271972-qhr6iir6	297	37	Host	Host	NNP
cord-271972-qhr6iir6	297	38	deadenylation	deadenylation	NN
cord-271972-qhr6iir6	297	39	-	-	HYPH
cord-271972-qhr6iir6	297	40	dependent	dependent	JJ
cord-271972-qhr6iir6	297	41	mRNA	mrna	NN
cord-271972-qhr6iir6	297	42	decapping	decapping	NN
cord-271972-qhr6iir6	297	43	factors	factor	NNS
cord-271972-qhr6iir6	297	44	are	be	VBP
cord-271972-qhr6iir6	297	45	required	require	VBN
cord-271972-qhr6iir6	297	46	for	for	IN
cord-271972-qhr6iir6	297	47	a	a	DT
cord-271972-qhr6iir6	297	48	key	key	JJ
cord-271972-qhr6iir6	297	49	step	step	NN
cord-271972-qhr6iir6	297	50	in	in	IN
cord-271972-qhr6iir6	297	51	brome	brome	NNP
cord-271972-qhr6iir6	297	52	mosaic	mosaic	NNP
cord-271972-qhr6iir6	297	53	virus	virus	NN
cord-271972-qhr6iir6	297	54	RNA	RNA	NNP
cord-271972-qhr6iir6	297	55	replication	replication	NN
cord-271972-qhr6iir6	297	56	Yeast	Yeast	NNP
cord-271972-qhr6iir6	297	57	Lsm1p-7p	Lsm1p-7p	NNP
cord-271972-qhr6iir6	297	58	/	/	SYM
cord-271972-qhr6iir6	297	59	Pat1p	pat1p	CC
cord-271972-qhr6iir6	297	60	dead	dead	JJ
cord-271972-qhr6iir6	297	61	-	-	HYPH
cord-271972-qhr6iir6	297	62	enylation	enylation	NN
cord-271972-qhr6iir6	297	63	-	-	HYPH
cord-271972-qhr6iir6	297	64	dependent	dependent	JJ
cord-271972-qhr6iir6	297	65	mRNAdecapping	mrnadecapping	NN
cord-271972-qhr6iir6	297	66	factors	factor	NNS
cord-271972-qhr6iir6	297	67	are	be	VBP
cord-271972-qhr6iir6	297	68	required	require	VBN
cord-271972-qhr6iir6	297	69	for	for	IN
cord-271972-qhr6iir6	297	70	brome	brome	NNP
cord-271972-qhr6iir6	297	71	mosaic	mosaic	NNP
cord-271972-qhr6iir6	297	72	virus	virus	NN
cord-271972-qhr6iir6	297	73	genomic	genomic	NNP
cord-271972-qhr6iir6	297	74	RNA	RNA	NNP
cord-271972-qhr6iir6	297	75	translation	translation	NN
cord-271972-qhr6iir6	297	76	Translation	translation	NN
cord-271972-qhr6iir6	297	77	and	and	CC
cord-271972-qhr6iir6	297	78	replication	replication	NN
cord-271972-qhr6iir6	297	79	of	of	IN
cord-271972-qhr6iir6	297	80	hepatitis	hepatitis	NN
cord-271972-qhr6iir6	297	81	C	C	NNP
cord-271972-qhr6iir6	297	82	virus	virus	NN
cord-271972-qhr6iir6	297	83	genomic	genomic	JJ
cord-271972-qhr6iir6	297	84	RNA	RNA	NNP
cord-271972-qhr6iir6	297	85	depends	depend	VBZ
cord-271972-qhr6iir6	297	86	on	on	IN
cord-271972-qhr6iir6	297	87	ancient	ancient	JJ
cord-271972-qhr6iir6	297	88	cellular	cellular	JJ
cord-271972-qhr6iir6	297	89	proteins	protein	NNS
cord-271972-qhr6iir6	297	90	that	that	WDT
cord-271972-qhr6iir6	297	91	control	control	VBP
cord-271972-qhr6iir6	297	92	mRNA	mrna	NN
cord-271972-qhr6iir6	297	93	fates	fate	NNS
cord-271972-qhr6iir6	297	94	Interactions	Interactions	NNPS
cord-271972-qhr6iir6	297	95	between	between	IN
cord-271972-qhr6iir6	297	96	brome	brome	NNP
cord-271972-qhr6iir6	297	97	mosaic	mosaic	NNP
cord-271972-qhr6iir6	297	98	virus	virus	NN
cord-271972-qhr6iir6	297	99	RNAs	rna	NNS
cord-271972-qhr6iir6	297	100	and	and	CC
cord-271972-qhr6iir6	297	101	cytoplasmic	cytoplasmic	JJ
cord-271972-qhr6iir6	297	102	processing	processing	NN
cord-271972-qhr6iir6	297	103	bodies	body	NNS
cord-271972-qhr6iir6	297	104	P	p	NN
cord-271972-qhr6iir6	297	105	bodies	body	NNS
cord-271972-qhr6iir6	297	106	:	:	:
cord-271972-qhr6iir6	297	107	at	at	IN
cord-271972-qhr6iir6	297	108	the	the	DT
cord-271972-qhr6iir6	297	109	crossroads	crossroad	NNS
cord-271972-qhr6iir6	297	110	of	of	IN
cord-271972-qhr6iir6	297	111	post	post	JJ
cord-271972-qhr6iir6	297	112	-	-	JJ
cord-271972-qhr6iir6	297	113	transcriptional	transcriptional	JJ
cord-271972-qhr6iir6	297	114	pathways	pathway	NNS
cord-271972-qhr6iir6	297	115	P	p	NN
cord-271972-qhr6iir6	297	116	bodies	body	NNS
cord-271972-qhr6iir6	297	117	and	and	CC
cord-271972-qhr6iir6	297	118	the	the	DT
cord-271972-qhr6iir6	297	119	control	control	NN
cord-271972-qhr6iir6	297	120	of	of	IN
cord-271972-qhr6iir6	297	121	mRNA	mRNA	NNP
cord-271972-qhr6iir6	297	122	translation	translation	NN
cord-271972-qhr6iir6	297	123	and	and	CC
cord-271972-qhr6iir6	297	124	degradation	degradation	NN
cord-271972-qhr6iir6	297	125	Stress	stress	NN
cord-271972-qhr6iir6	297	126	granules	granule	NNS
cord-271972-qhr6iir6	297	127	and	and	CC
cord-271972-qhr6iir6	297	128	processing	processing	NN
cord-271972-qhr6iir6	297	129	bodies	body	NNS
cord-271972-qhr6iir6	297	130	are	be	VBP
cord-271972-qhr6iir6	297	131	dynamically	dynamically	RB
cord-271972-qhr6iir6	297	132	linked	link	VBN
cord-271972-qhr6iir6	297	133	sites	site	NNS
cord-271972-qhr6iir6	297	134	of	of	IN
cord-271972-qhr6iir6	297	135	mRNP	mRNP	``
cord-271972-qhr6iir6	297	136	remodeling	remodel	VBG
cord-271972-qhr6iir6	297	137	Deadenylation	Deadenylation	NNP
cord-271972-qhr6iir6	297	138	is	be	VBZ
cord-271972-qhr6iir6	297	139	prerequisite	prerequisite	JJ
cord-271972-qhr6iir6	297	140	for	for	IN
cord-271972-qhr6iir6	297	141	P	p	NN
cord-271972-qhr6iir6	297	142	-	-	HYPH
cord-271972-qhr6iir6	297	143	body	body	NN
cord-271972-qhr6iir6	297	144	formation	formation	NN
cord-271972-qhr6iir6	297	145	and	and	CC
cord-271972-qhr6iir6	297	146	mRNA	mrna	NN
cord-271972-qhr6iir6	297	147	decay	decay	NN
cord-271972-qhr6iir6	297	148	in	in	IN
cord-271972-qhr6iir6	297	149	mammalian	mammalian	JJ
cord-271972-qhr6iir6	297	150	cells	cell	NNS
cord-271972-qhr6iir6	297	151	Discontinuous	discontinuous	JJ
cord-271972-qhr6iir6	297	152	transcription	transcription	NN
cord-271972-qhr6iir6	297	153	or	or	CC
cord-271972-qhr6iir6	297	154	RNA	RNA	NNP
cord-271972-qhr6iir6	297	155	processing	processing	NN
cord-271972-qhr6iir6	297	156	of	of	IN
cord-271972-qhr6iir6	297	157	vaccinia	vaccinia	NN
cord-271972-qhr6iir6	297	158	virus	virus	NN
cord-271972-qhr6iir6	297	159	late	late	JJ
cord-271972-qhr6iir6	297	160	messengers	messenger	NNS
cord-271972-qhr6iir6	297	161	results	result	VBZ
cord-271972-qhr6iir6	297	162	in	in	IN
cord-271972-qhr6iir6	297	163	a	a	DT
cord-271972-qhr6iir6	297	164	5	5	CD
cord-271972-qhr6iir6	297	165	poly(A	poly(a	NN
cord-271972-qhr6iir6	297	166	)	)	-RRB-
cord-271972-qhr6iir6	298	1	leader	leader	NN
cord-271972-qhr6iir6	298	2	Lsm	Lsm	NNP
cord-271972-qhr6iir6	298	3	proteins	protein	NNS
cord-271972-qhr6iir6	298	4	bind	bind	VBP
cord-271972-qhr6iir6	298	5	and	and	CC
cord-271972-qhr6iir6	298	6	stabilize	stabilize	VBP
cord-271972-qhr6iir6	298	7	RNAs	rna	NNS
cord-271972-qhr6iir6	298	8	containing	contain	VBG
cord-271972-qhr6iir6	298	9	5	5	CD
cord-271972-qhr6iir6	298	10	poly(A	poly(a	JJ
cord-271972-qhr6iir6	298	11	)	)	-RRB-
cord-271972-qhr6iir6	298	12	tracts	tract	NNS
cord-271972-qhr6iir6	298	13	Characterization	characterization	NN
cord-271972-qhr6iir6	298	14	of	of	IN
cord-271972-qhr6iir6	298	15	a	a	DT
cord-271972-qhr6iir6	298	16	vaccinia	vaccinia	NN
cord-271972-qhr6iir6	298	17	virus	virus	NN
cord-271972-qhr6iir6	298	18	mutant	mutant	JJ
cord-271972-qhr6iir6	298	19	with	with	IN
cord-271972-qhr6iir6	298	20	a	a	DT
cord-271972-qhr6iir6	298	21	deletion	deletion	NN
cord-271972-qhr6iir6	298	22	of	of	IN
cord-271972-qhr6iir6	298	23	the	the	DT
cord-271972-qhr6iir6	298	24	D10R	d10r	NN
cord-271972-qhr6iir6	298	25	gene	gene	NN
cord-271972-qhr6iir6	298	26	encoding	encode	VBG
cord-271972-qhr6iir6	298	27	a	a	DT
cord-271972-qhr6iir6	298	28	putative	putative	JJ
cord-271972-qhr6iir6	298	29	negative	negative	JJ
cord-271972-qhr6iir6	298	30	regulator	regulator	NN
cord-271972-qhr6iir6	298	31	of	of	IN
cord-271972-qhr6iir6	298	32	gene	gene	NN
cord-271972-qhr6iir6	298	33	expression	expression	NN
cord-271972-qhr6iir6	299	1	Vaccinia	vaccinia	NN
cord-271972-qhr6iir6	299	2	virus	virus	NN
cord-271972-qhr6iir6	299	3	D10	D10	NNP
cord-271972-qhr6iir6	299	4	protein	protein	NN
cord-271972-qhr6iir6	299	5	has	have	VBZ
cord-271972-qhr6iir6	299	6	mRNA	mrna	NN
cord-271972-qhr6iir6	299	7	decapping	decapping	NN
cord-271972-qhr6iir6	299	8	activity	activity	NN
cord-271972-qhr6iir6	299	9	,	,	,
cord-271972-qhr6iir6	299	10	providing	provide	VBG
cord-271972-qhr6iir6	299	11	a	a	DT
cord-271972-qhr6iir6	299	12	mechanism	mechanism	NN
cord-271972-qhr6iir6	299	13	for	for	IN
cord-271972-qhr6iir6	299	14	control	control	NN
cord-271972-qhr6iir6	299	15	of	of	IN
cord-271972-qhr6iir6	299	16	host	host	NN
cord-271972-qhr6iir6	299	17	and	and	CC
cord-271972-qhr6iir6	299	18	viral	viral	JJ
cord-271972-qhr6iir6	299	19	gene	gene	NN
cord-271972-qhr6iir6	299	20	expression	expression	NN
cord-271972-qhr6iir6	299	21	Down	down	IN
cord-271972-qhr6iir6	299	22	regulation	regulation	NN
cord-271972-qhr6iir6	299	23	of	of	IN
cord-271972-qhr6iir6	299	24	gene	gene	NN
cord-271972-qhr6iir6	299	25	expression	expression	NN
cord-271972-qhr6iir6	299	26	by	by	IN
cord-271972-qhr6iir6	299	27	the	the	DT
cord-271972-qhr6iir6	299	28	vaccinia	vaccinia	NN
cord-271972-qhr6iir6	299	29	virus	virus	NN
cord-271972-qhr6iir6	299	30	D10	D10	NNP
cord-271972-qhr6iir6	299	31	protein	protein	NN
cord-271972-qhr6iir6	299	32	Chromosomal	chromosomal	JJ
cord-271972-qhr6iir6	299	33	superkiller	superkiller	NN
cord-271972-qhr6iir6	299	34	mutants	mutant	NNS
cord-271972-qhr6iir6	299	35	of	of	IN
cord-271972-qhr6iir6	299	36	Saccharomyces	saccharomyce	NNS
cord-271972-qhr6iir6	299	37	cerevisiae	cerevisiae	VBZ
cord-271972-qhr6iir6	299	38	Suppression	suppression	NN
cord-271972-qhr6iir6	299	39	of	of	IN
cord-271972-qhr6iir6	299	40	viral	viral	JJ
cord-271972-qhr6iir6	299	41	RNA	RNA	NNP
cord-271972-qhr6iir6	299	42	recombination	recombination	NN
cord-271972-qhr6iir6	299	43	by	by	IN
cord-271972-qhr6iir6	299	44	a	a	DT
cord-271972-qhr6iir6	299	45	host	host	NN
cord-271972-qhr6iir6	299	46	exoribonuclease	exoribonuclease	NN
cord-271972-qhr6iir6	299	47	Silencing	silencing	NN
cord-271972-qhr6iir6	299	48	of	of	IN
cord-271972-qhr6iir6	299	49	Nicotiana	Nicotiana	NNP
cord-271972-qhr6iir6	299	50	benthamiana	benthamiana	NNP
cord-271972-qhr6iir6	300	1	Xrn4p	Xrn4p	NNP
cord-271972-qhr6iir6	300	2	exoribonuclease	exoribonuclease	NNP
cord-271972-qhr6iir6	300	3	promotes	promote	VBZ
cord-271972-qhr6iir6	300	4	tombusvirus	tombusvirus	NNP
cord-271972-qhr6iir6	300	5	RNA	RNA	NNP
cord-271972-qhr6iir6	300	6	accumulation	accumulation	NN
cord-271972-qhr6iir6	300	7	and	and	CC
cord-271972-qhr6iir6	300	8	recombination	recombination	NN
cord-271972-qhr6iir6	300	9	Virus	virus	NN
cord-271972-qhr6iir6	300	10	evolution	evolution	NN
cord-271972-qhr6iir6	301	1	20S	20S	NNP
cord-271972-qhr6iir6	301	2	RNA	RNA	NNP
cord-271972-qhr6iir6	301	3	narnavirus	narnavirus	NNP
cord-271972-qhr6iir6	301	4	defies	defy	VBZ
cord-271972-qhr6iir6	301	5	the	the	DT
cord-271972-qhr6iir6	301	6	antiviral	antiviral	JJ
cord-271972-qhr6iir6	301	7	activity	activity	NN
cord-271972-qhr6iir6	301	8	of	of	IN
cord-271972-qhr6iir6	301	9	SKI1	SKI1	NNP
cord-271972-qhr6iir6	301	10	/	/	SYM
cord-271972-qhr6iir6	301	11	XRN1	XRN1	NNP
cord-271972-qhr6iir6	301	12	in	in	IN
cord-271972-qhr6iir6	301	13	Saccharomyces	Saccharomyces	NNP
cord-271972-qhr6iir6	301	14	cerevisiae	cerevisiae	VBZ
cord-271972-qhr6iir6	301	15	Poly(rC	poly(rc	CD
cord-271972-qhr6iir6	301	16	)	)	-RRB-
cord-271972-qhr6iir6	302	1	binding	bind	VBG
cord-271972-qhr6iir6	302	2	proteins	protein	NNS
cord-271972-qhr6iir6	302	3	mediate	mediate	VBP
cord-271972-qhr6iir6	302	4	poliovirus	poliovirus	NN
cord-271972-qhr6iir6	302	5	mRNA	mrna	NN
cord-271972-qhr6iir6	302	6	stability	stability	NN
cord-271972-qhr6iir6	302	7	Poly(rC	poly(rc	CD
cord-271972-qhr6iir6	302	8	)	)	-RRB-
cord-271972-qhr6iir6	303	1	binding	bind	VBG
cord-271972-qhr6iir6	303	2	proteins	protein	NNS
cord-271972-qhr6iir6	303	3	and	and	CC
cord-271972-qhr6iir6	303	4	the	the	DT
cord-271972-qhr6iir6	303	5	5	5	CD
cord-271972-qhr6iir6	303	6	cloverleaf	cloverleaf	NN
cord-271972-qhr6iir6	303	7	of	of	IN
cord-271972-qhr6iir6	304	1	uncapped	uncapped	JJ
cord-271972-qhr6iir6	304	2	poliovirus	poliovirus	NN
cord-271972-qhr6iir6	304	3	mRNA	mRNA	NNP
cord-271972-qhr6iir6	304	4	function	function	NN
cord-271972-qhr6iir6	304	5	during	during	IN
cord-271972-qhr6iir6	304	6	de	de	NNP
cord-271972-qhr6iir6	304	7	novo	novo	NNP
cord-271972-qhr6iir6	304	8	assembly	assembly	NNP
cord-271972-qhr6iir6	304	9	of	of	IN
cord-271972-qhr6iir6	304	10	polysomes	polysomes	NNP
cord-271972-qhr6iir6	304	11	Application	Application	NNP
cord-271972-qhr6iir6	304	12	of	of	IN
cord-271972-qhr6iir6	304	13	genome	genome	NN
cord-271972-qhr6iir6	304	14	sequence	sequence	NN
cord-271972-qhr6iir6	304	15	information	information	NN
cord-271972-qhr6iir6	304	16	to	to	IN
cord-271972-qhr6iir6	304	17	the	the	DT
cord-271972-qhr6iir6	304	18	classification	classification	NN
cord-271972-qhr6iir6	304	19	of	of	IN
cord-271972-qhr6iir6	304	20	bovine	bovine	JJ
cord-271972-qhr6iir6	304	21	enteroviruses	enterovirus	NNS
cord-271972-qhr6iir6	304	22	:	:	:
cord-271972-qhr6iir6	304	23	the	the	DT
cord-271972-qhr6iir6	304	24	importance	importance	NN
cord-271972-qhr6iir6	304	25	of	of	IN
cord-271972-qhr6iir6	304	26	5	5	CD
cord-271972-qhr6iir6	304	27	-and	-and	SYM
cord-271972-qhr6iir6	304	28	3	3	CD
cord-271972-qhr6iir6	304	29	-nontranslated	-nontranslated	JJ
cord-271972-qhr6iir6	304	30	regions	region	NNS
cord-271972-qhr6iir6	305	1	A	a	DT
cord-271972-qhr6iir6	305	2	highly	highly	RB
cord-271972-qhr6iir6	305	3	structured	structure	VBN
cord-271972-qhr6iir6	305	4	,	,	,
cord-271972-qhr6iir6	305	5	nucleaseresistant	nucleaseresistant	NNP
cord-271972-qhr6iir6	305	6	,	,	,
cord-271972-qhr6iir6	305	7	noncoding	noncoding	NNP
cord-271972-qhr6iir6	305	8	RNA	RNA	NNP
cord-271972-qhr6iir6	305	9	produced	produce	VBN
cord-271972-qhr6iir6	305	10	by	by	IN
cord-271972-qhr6iir6	305	11	flaviviruses	flavivirus	NNS
cord-271972-qhr6iir6	305	12	is	be	VBZ
cord-271972-qhr6iir6	305	13	required	require	VBN
cord-271972-qhr6iir6	305	14	for	for	IN
cord-271972-qhr6iir6	305	15	pathogenicity	pathogenicity	NN
cord-271972-qhr6iir6	306	1	The	the	DT
cord-271972-qhr6iir6	306	2	exosome	exosome	NN
cord-271972-qhr6iir6	306	3	:	:	:
cord-271972-qhr6iir6	306	4	a	a	DT
cord-271972-qhr6iir6	306	5	multipurpose	multipurpose	JJ
cord-271972-qhr6iir6	306	6	RNA	rna	NN
cord-271972-qhr6iir6	306	7	-	-	HYPH
cord-271972-qhr6iir6	306	8	decay	decay	NN
cord-271972-qhr6iir6	306	9	machine	machine	NN
cord-271972-qhr6iir6	306	10	Inhibition	inhibition	NN
cord-271972-qhr6iir6	306	11	of	of	IN
cord-271972-qhr6iir6	306	12	retroviral	retroviral	JJ
cord-271972-qhr6iir6	306	13	RNA	rna	NN
cord-271972-qhr6iir6	306	14	production	production	NN
cord-271972-qhr6iir6	306	15	by	by	IN
cord-271972-qhr6iir6	306	16	ZAP	ZAP	NNP
cord-271972-qhr6iir6	306	17	,	,	,
cord-271972-qhr6iir6	306	18	a	a	DT
cord-271972-qhr6iir6	306	19	CCCH	CCCH	NNP
cord-271972-qhr6iir6	306	20	-	-	HYPH
cord-271972-qhr6iir6	306	21	type	type	NN
cord-271972-qhr6iir6	306	22	zinc	zinc	NN
cord-271972-qhr6iir6	306	23	finger	finger	NN
cord-271972-qhr6iir6	306	24	protein	protein	NN
cord-271972-qhr6iir6	306	25	Expression	expression	NN
cord-271972-qhr6iir6	306	26	of	of	IN
cord-271972-qhr6iir6	306	27	the	the	DT
cord-271972-qhr6iir6	306	28	zinc	zinc	NN
cord-271972-qhr6iir6	306	29	-	-	HYPH
cord-271972-qhr6iir6	306	30	finger	finger	NN
cord-271972-qhr6iir6	306	31	antiviral	antiviral	JJ
cord-271972-qhr6iir6	306	32	protein	protein	NN
cord-271972-qhr6iir6	307	1	inhibits	inhibit	VBZ
cord-271972-qhr6iir6	307	2	alphavirus	alphavirus	NNP
cord-271972-qhr6iir6	307	3	replication	replication	NN
cord-271972-qhr6iir6	307	4	Inhibition	inhibition	NN
cord-271972-qhr6iir6	307	5	of	of	IN
cord-271972-qhr6iir6	307	6	filovirus	filovirus	NN
cord-271972-qhr6iir6	307	7	replication	replication	NN
cord-271972-qhr6iir6	307	8	by	by	IN
cord-271972-qhr6iir6	307	9	the	the	DT
cord-271972-qhr6iir6	307	10	zinc	zinc	NN
cord-271972-qhr6iir6	307	11	finger	finger	NN
cord-271972-qhr6iir6	307	12	antiviral	antiviral	JJ
cord-271972-qhr6iir6	307	13	protein	protein	NN
cord-271972-qhr6iir6	308	1	The	the	DT
cord-271972-qhr6iir6	308	2	zinc	zinc	NN
cord-271972-qhr6iir6	308	3	-	-	HYPH
cord-271972-qhr6iir6	308	4	finger	finger	NN
cord-271972-qhr6iir6	308	5	antiviral	antiviral	JJ
cord-271972-qhr6iir6	308	6	protein	protein	NN
cord-271972-qhr6iir6	308	7	recruits	recruit	VBZ
cord-271972-qhr6iir6	308	8	the	the	DT
cord-271972-qhr6iir6	308	9	RNA	RNA	NNP
cord-271972-qhr6iir6	308	10	processing	processing	NN
cord-271972-qhr6iir6	308	11	exosome	exosome	NN
cord-271972-qhr6iir6	308	12	to	to	TO
cord-271972-qhr6iir6	308	13	degrade	degrade	VB
cord-271972-qhr6iir6	308	14	the	the	DT
cord-271972-qhr6iir6	308	15	target	target	NN
cord-271972-qhr6iir6	309	1	mRNA	mRNA	NNP
cord-271972-qhr6iir6	310	1	The	the	DT
cord-271972-qhr6iir6	310	2	zinc	zinc	NN
cord-271972-qhr6iir6	310	3	finger	finger	NN
cord-271972-qhr6iir6	310	4	antiviral	antiviral	JJ
cord-271972-qhr6iir6	310	5	protein	protein	NN
cord-271972-qhr6iir6	310	6	directly	directly	RB
cord-271972-qhr6iir6	310	7	binds	bind	VBZ
cord-271972-qhr6iir6	310	8	to	to	IN
cord-271972-qhr6iir6	310	9	specific	specific	JJ
cord-271972-qhr6iir6	310	10	viral	viral	NN
cord-271972-qhr6iir6	310	11	mRNAs	mrnas	TO
cord-271972-qhr6iir6	310	12	through	through	IN
cord-271972-qhr6iir6	310	13	the	the	DT
cord-271972-qhr6iir6	310	14	CCCH	CCCH	NNP
cord-271972-qhr6iir6	310	15	zinc	zinc	NN
cord-271972-qhr6iir6	310	16	finger	finger	NN
cord-271972-qhr6iir6	310	17	motifs	motif	NNS
cord-271972-qhr6iir6	311	1	Lytic	lytic	JJ
cord-271972-qhr6iir6	311	2	KSHV	KSHV	NNP
cord-271972-qhr6iir6	311	3	infection	infection	NN
cord-271972-qhr6iir6	311	4	inhibits	inhibit	VBZ
cord-271972-qhr6iir6	311	5	host	host	NN
cord-271972-qhr6iir6	311	6	gene	gene	NN
cord-271972-qhr6iir6	311	7	expression	expression	NN
cord-271972-qhr6iir6	311	8	by	by	IN
cord-271972-qhr6iir6	311	9	accelerating	accelerate	VBG
cord-271972-qhr6iir6	311	10	global	global	JJ
cord-271972-qhr6iir6	311	11	mRNA	mRNA	NNP
cord-271972-qhr6iir6	311	12	turnover	turnover	NN
cord-271972-qhr6iir6	311	13	Herpes	Herpes	NNP
cord-271972-qhr6iir6	311	14	simplex	simplex	NN
cord-271972-qhr6iir6	311	15	virus	virus	NN
cord-271972-qhr6iir6	311	16	-	-	HYPH
cord-271972-qhr6iir6	311	17	infected	infect	VBN
cord-271972-qhr6iir6	311	18	cells	cell	NNS
cord-271972-qhr6iir6	311	19	contain	contain	VBP
cord-271972-qhr6iir6	311	20	a	a	DT
cord-271972-qhr6iir6	311	21	function(s	function(s	NNP
cord-271972-qhr6iir6	311	22	)	)	-RRB-
cord-271972-qhr6iir6	311	23	that	that	WDT
cord-271972-qhr6iir6	311	24	destabilizes	destabilize	VBZ
cord-271972-qhr6iir6	311	25	both	both	DT
cord-271972-qhr6iir6	311	26	host	host	NN
cord-271972-qhr6iir6	311	27	and	and	CC
cord-271972-qhr6iir6	311	28	viral	viral	JJ
cord-271972-qhr6iir6	312	1	mRNAs	mRNAs	.
cord-271972-qhr6iir6	313	1	Aberrant	aberrant	JJ
cord-271972-qhr6iir6	313	2	herpesvirusinduced	herpesvirusinduced	JJ
cord-271972-qhr6iir6	313	3	polyadenylation	polyadenylation	NN
cord-271972-qhr6iir6	313	4	correlates	correlate	VBZ
cord-271972-qhr6iir6	313	5	with	with	IN
cord-271972-qhr6iir6	313	6	cellular	cellular	JJ
cord-271972-qhr6iir6	313	7	messenger	messenger	NN
cord-271972-qhr6iir6	313	8	RNA	RNA	NNP
cord-271972-qhr6iir6	314	1	destruction	destruction	NN
cord-271972-qhr6iir6	314	2	Severe	severe	JJ
cord-271972-qhr6iir6	314	3	acute	acute	JJ
cord-271972-qhr6iir6	314	4	respiratory	respiratory	JJ
cord-271972-qhr6iir6	314	5	syndrome	syndrome	NN
cord-271972-qhr6iir6	314	6	coronavirus	coronavirus	NN
cord-271972-qhr6iir6	314	7	nsp1	nsp1	CD
cord-271972-qhr6iir6	314	8	suppresses	suppress	VBZ
cord-271972-qhr6iir6	314	9	host	host	NN
cord-271972-qhr6iir6	314	10	gene	gene	NN
cord-271972-qhr6iir6	314	11	expression	expression	NN
cord-271972-qhr6iir6	314	12	,	,	,
cord-271972-qhr6iir6	314	13	including	include	VBG
cord-271972-qhr6iir6	314	14	that	that	DT
cord-271972-qhr6iir6	314	15	of	of	IN
cord-271972-qhr6iir6	314	16	type	type	NN
cord-271972-qhr6iir6	315	1	I	-PRON-	PRP
cord-271972-qhr6iir6	315	2	interferon	interferon	VBD
cord-271972-qhr6iir6	315	3	,	,	,
cord-271972-qhr6iir6	315	4	in	in	IN
cord-271972-qhr6iir6	315	5	infected	infected	JJ
cord-271972-qhr6iir6	315	6	cells	cell	NNS
cord-271972-qhr6iir6	315	7	Suppression	Suppression	NNP
cord-271972-qhr6iir6	315	8	of	of	IN
cord-271972-qhr6iir6	315	9	host	host	NN
cord-271972-qhr6iir6	315	10	gene	gene	NN
cord-271972-qhr6iir6	315	11	expression	expression	NN
cord-271972-qhr6iir6	315	12	by	by	IN
cord-271972-qhr6iir6	315	13	nsp1	nsp1	NNS
cord-271972-qhr6iir6	315	14	proteins	protein	NNS
cord-271972-qhr6iir6	315	15	of	of	IN
cord-271972-qhr6iir6	315	16	group	group	NN
cord-271972-qhr6iir6	315	17	2	2	CD
cord-271972-qhr6iir6	315	18	bat	bat	NN
cord-271972-qhr6iir6	315	19	coronaviruses	coronaviruse	VBZ
cord-271972-qhr6iir6	315	20	Recognition	recognition	NN
cord-271972-qhr6iir6	315	21	and	and	CC
cord-271972-qhr6iir6	315	22	elimination	elimination	NN
cord-271972-qhr6iir6	315	23	of	of	IN
cord-271972-qhr6iir6	315	24	nonsense	nonsense	NN
cord-271972-qhr6iir6	316	1	mRNA	mRNA	NNP
cord-271972-qhr6iir6	317	1	SMG6	SMG6	NNP
cord-271972-qhr6iir6	317	2	promotes	promote	VBZ
cord-271972-qhr6iir6	317	3	endonucleolytic	endonucleolytic	JJ
cord-271972-qhr6iir6	317	4	cleavage	cleavage	NN
cord-271972-qhr6iir6	317	5	of	of	IN
cord-271972-qhr6iir6	317	6	nonsense	nonsense	NN
cord-271972-qhr6iir6	318	1	mRNA	mrna	NN
cord-271972-qhr6iir6	318	2	in	in	IN
cord-271972-qhr6iir6	318	3	human	human	JJ
cord-271972-qhr6iir6	318	4	cells	cell	NNS
cord-271972-qhr6iir6	319	1	Izaurralde	Izaurralde	NNP
cord-271972-qhr6iir6	319	2	E.	E.	NNP
cord-271972-qhr6iir6	319	3	SMG6	SMG6	NNP
cord-271972-qhr6iir6	319	4	is	be	VBZ
cord-271972-qhr6iir6	319	5	the	the	DT
cord-271972-qhr6iir6	319	6	catalytic	catalytic	JJ
cord-271972-qhr6iir6	319	7	endonuclease	endonuclease	NN
cord-271972-qhr6iir6	319	8	that	that	WDT
cord-271972-qhr6iir6	319	9	cleaves	cleave	VBZ
cord-271972-qhr6iir6	319	10	mRNAs	mrnas	XX
cord-271972-qhr6iir6	319	11	containing	contain	VBG
cord-271972-qhr6iir6	319	12	nonsense	nonsense	NN
cord-271972-qhr6iir6	319	13	codons	codon	NNS
cord-271972-qhr6iir6	319	14	in	in	IN
cord-271972-qhr6iir6	319	15	metazoan	metazoan	NN
cord-271972-qhr6iir6	319	16	Quality	Quality	NNP
cord-271972-qhr6iir6	319	17	control	control	NN
cord-271972-qhr6iir6	319	18	of	of	IN
cord-271972-qhr6iir6	319	19	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	319	20	mRNA	mrna	NN
cord-271972-qhr6iir6	319	21	:	:	:
cord-271972-qhr6iir6	319	22	safeguarding	safeguard	VBG
cord-271972-qhr6iir6	319	23	cells	cell	NNS
cord-271972-qhr6iir6	319	24	from	from	IN
cord-271972-qhr6iir6	319	25	abnormal	abnormal	JJ
cord-271972-qhr6iir6	319	26	mRNA	mrna	NN
cord-271972-qhr6iir6	319	27	function	function	NN
cord-271972-qhr6iir6	320	1	At	at	RB
cord-271972-qhr6iir6	320	2	least	least	RBS
cord-271972-qhr6iir6	320	3	one	one	CD
cord-271972-qhr6iir6	320	4	intron	intron	NN
cord-271972-qhr6iir6	320	5	is	be	VBZ
cord-271972-qhr6iir6	320	6	required	require	VBN
cord-271972-qhr6iir6	320	7	for	for	IN
cord-271972-qhr6iir6	320	8	the	the	DT
cord-271972-qhr6iir6	320	9	nonsensemediated	nonsensemediated	JJ
cord-271972-qhr6iir6	320	10	decay	decay	NN
cord-271972-qhr6iir6	320	11	of	of	IN
cord-271972-qhr6iir6	320	12	triosephosphate	triosephosphate	NNP
cord-271972-qhr6iir6	320	13	isomerase	isomerase	NN
cord-271972-qhr6iir6	320	14	mRNA	mRNA	NNP
cord-271972-qhr6iir6	320	15	:	:	:
cord-271972-qhr6iir6	320	16	a	a	DT
cord-271972-qhr6iir6	320	17	possible	possible	JJ
cord-271972-qhr6iir6	320	18	link	link	NN
cord-271972-qhr6iir6	320	19	between	between	IN
cord-271972-qhr6iir6	320	20	nuclear	nuclear	JJ
cord-271972-qhr6iir6	320	21	splicing	splicing	NN
cord-271972-qhr6iir6	320	22	and	and	CC
cord-271972-qhr6iir6	320	23	cytoplasmic	cytoplasmic	JJ
cord-271972-qhr6iir6	320	24	translation	translation	NN
cord-271972-qhr6iir6	321	1	Intron	intron	NN
cord-271972-qhr6iir6	321	2	function	function	NN
cord-271972-qhr6iir6	321	3	in	in	IN
cord-271972-qhr6iir6	321	4	the	the	DT
cord-271972-qhr6iir6	321	5	nonsense	nonsense	NN
cord-271972-qhr6iir6	321	6	-	-	HYPH
cord-271972-qhr6iir6	321	7	mediated	mediate	VBN
cord-271972-qhr6iir6	321	8	decay	decay	NN
cord-271972-qhr6iir6	321	9	of	of	IN
cord-271972-qhr6iir6	321	10	beta	beta	NN
cord-271972-qhr6iir6	321	11	-	-	HYPH
cord-271972-qhr6iir6	321	12	globin	globin	NN
cord-271972-qhr6iir6	322	1	mRNA	mrna	NN
cord-271972-qhr6iir6	322	2	:	:	:
cord-271972-qhr6iir6	322	3	indications	indication	NNS
cord-271972-qhr6iir6	322	4	that	that	IN
cord-271972-qhr6iir6	322	5	pre	pre	JJ
cord-271972-qhr6iir6	322	6	-	-	JJ
cord-271972-qhr6iir6	322	7	mRNA	mrna	JJ
cord-271972-qhr6iir6	322	8	splicing	splicing	NN
cord-271972-qhr6iir6	322	9	in	in	IN
cord-271972-qhr6iir6	322	10	the	the	DT
cord-271972-qhr6iir6	322	11	nucleus	nucleus	NN
cord-271972-qhr6iir6	322	12	can	can	MD
cord-271972-qhr6iir6	322	13	influence	influence	VB
cord-271972-qhr6iir6	322	14	mRNA	mRNA	NNP
cord-271972-qhr6iir6	322	15	translation	translation	NN
cord-271972-qhr6iir6	322	16	in	in	IN
cord-271972-qhr6iir6	322	17	the	the	DT
cord-271972-qhr6iir6	322	18	cytoplasm	cytoplasm	JJ
cord-271972-qhr6iir6	322	19	Posttranscriptional	Posttranscriptional	NNP
cord-271972-qhr6iir6	322	20	gene	gene	NN
cord-271972-qhr6iir6	322	21	regulation	regulation	NN
cord-271972-qhr6iir6	322	22	by	by	IN
cord-271972-qhr6iir6	322	23	spatial	spatial	JJ
cord-271972-qhr6iir6	322	24	rearrangement	rearrangement	NN
cord-271972-qhr6iir6	322	25	of	of	IN
cord-271972-qhr6iir6	322	26	the	the	DT
cord-271972-qhr6iir6	322	27	3	3	CD
cord-271972-qhr6iir6	322	28	untranslated	untranslated	JJ
cord-271972-qhr6iir6	322	29	region	region	NN
cord-271972-qhr6iir6	322	30	Interactions	Interactions	NNPS
cord-271972-qhr6iir6	322	31	between	between	IN
cord-271972-qhr6iir6	322	32	UPF1	UPF1	NNP
cord-271972-qhr6iir6	322	33	,	,	,
cord-271972-qhr6iir6	322	34	eRFs	erfs	ADD
cord-271972-qhr6iir6	322	35	PABP	PABP	NNP
cord-271972-qhr6iir6	322	36	and	and	CC
cord-271972-qhr6iir6	322	37	the	the	DT
cord-271972-qhr6iir6	322	38	exon	exon	NN
cord-271972-qhr6iir6	322	39	junction	junction	NN
cord-271972-qhr6iir6	322	40	complex	complex	NN
cord-271972-qhr6iir6	322	41	suggest	suggest	VBP
cord-271972-qhr6iir6	322	42	an	an	DT
cord-271972-qhr6iir6	322	43	integrated	integrated	JJ
cord-271972-qhr6iir6	322	44	model	model	NN
cord-271972-qhr6iir6	322	45	for	for	IN
cord-271972-qhr6iir6	322	46	mammalian	mammalian	JJ
cord-271972-qhr6iir6	322	47	NMD	NMD	NNP
cord-271972-qhr6iir6	322	48	pathways	pathway	NNS
cord-271972-qhr6iir6	323	1	A	a	DT
cord-271972-qhr6iir6	323	2	competition	competition	NN
cord-271972-qhr6iir6	323	3	between	between	IN
cord-271972-qhr6iir6	323	4	stimulators	stimulator	NNS
cord-271972-qhr6iir6	323	5	and	and	CC
cord-271972-qhr6iir6	323	6	antagonists	antagonist	NNS
cord-271972-qhr6iir6	323	7	of	of	IN
cord-271972-qhr6iir6	323	8	Upf	Upf	NNP
cord-271972-qhr6iir6	323	9	complex	complex	JJ
cord-271972-qhr6iir6	323	10	recruitment	recruitment	NN
cord-271972-qhr6iir6	323	11	governs	govern	VBZ
cord-271972-qhr6iir6	323	12	human	human	JJ
cord-271972-qhr6iir6	323	13	nonsensemediated	nonsensemediated	JJ
cord-271972-qhr6iir6	323	14	mRNA	mRNA	NNP
cord-271972-qhr6iir6	323	15	decay	decay	NN
cord-271972-qhr6iir6	323	16	Splicing	Splicing	NNP
cord-271972-qhr6iir6	323	17	of	of	IN
cord-271972-qhr6iir6	323	18	human	human	JJ
cord-271972-qhr6iir6	323	19	immunodeficiency	immunodeficiency	NN
cord-271972-qhr6iir6	323	20	virus	virus	NN
cord-271972-qhr6iir6	323	21	RNA	RNA	NNP
cord-271972-qhr6iir6	324	1	is	be	VBZ
cord-271972-qhr6iir6	324	2	positiondependent	positiondependent	NNP
cord-271972-qhr6iir6	324	3	suggesting	suggest	VBG
cord-271972-qhr6iir6	324	4	sequential	sequential	JJ
cord-271972-qhr6iir6	324	5	removal	removal	NN
cord-271972-qhr6iir6	324	6	of	of	IN
cord-271972-qhr6iir6	324	7	introns	intron	NNS
cord-271972-qhr6iir6	324	8	from	from	IN
cord-271972-qhr6iir6	324	9	the	the	DT
cord-271972-qhr6iir6	324	10	5	5	CD
cord-271972-qhr6iir6	324	11	end	end	NN
cord-271972-qhr6iir6	325	1	A	a	DT
cord-271972-qhr6iir6	325	2	3	3	CD
cord-271972-qhr6iir6	325	3	UTR	UTR	NNP
cord-271972-qhr6iir6	325	4	sequence	sequence	NN
cord-271972-qhr6iir6	325	5	stabilizes	stabilize	VBZ
cord-271972-qhr6iir6	325	6	termination	termination	NN
cord-271972-qhr6iir6	325	7	codons	codon	NNS
cord-271972-qhr6iir6	325	8	in	in	IN
cord-271972-qhr6iir6	325	9	the	the	DT
cord-271972-qhr6iir6	325	10	unspliced	unspliced	NNP
cord-271972-qhr6iir6	325	11	RNA	RNA	NNP
cord-271972-qhr6iir6	325	12	of	of	IN
cord-271972-qhr6iir6	325	13	Rous	rous	JJ
cord-271972-qhr6iir6	325	14	sarcoma	sarcoma	NN
cord-271972-qhr6iir6	325	15	virus	virus	NN
cord-271972-qhr6iir6	325	16	Structural	structural	JJ
cord-271972-qhr6iir6	325	17	characterization	characterization	NN
cord-271972-qhr6iir6	325	18	of	of	IN
cord-271972-qhr6iir6	325	19	the	the	DT
cord-271972-qhr6iir6	325	20	Rous	rous	JJ
cord-271972-qhr6iir6	325	21	sarcoma	sarcoma	NN
cord-271972-qhr6iir6	325	22	virus	virus	NN
cord-271972-qhr6iir6	325	23	RNA	rna	NN
cord-271972-qhr6iir6	325	24	stability	stability	NN
cord-271972-qhr6iir6	325	25	element	element	NN
cord-271972-qhr6iir6	325	26	Togaviridiae	Togaviridiae	NNP
cord-271972-qhr6iir6	325	27	:	:	:
cord-271972-qhr6iir6	325	28	the	the	DT
cord-271972-qhr6iir6	325	29	viruses	virus	NNS
cord-271972-qhr6iir6	325	30	and	and	CC
cord-271972-qhr6iir6	325	31	their	-PRON-	PRP$
cord-271972-qhr6iir6	325	32	replication	replication	NN
cord-271972-qhr6iir6	325	33	Kaposi	Kaposi	NNP
cord-271972-qhr6iir6	325	34	's	's	POS
cord-271972-qhr6iir6	325	35	Sarcoma	Sarcoma	NNP
cord-271972-qhr6iir6	325	36	-	-	HYPH
cord-271972-qhr6iir6	325	37	associated	associate	VBN
cord-271972-qhr6iir6	325	38	herpesvirus	herpesvirus	NN
cord-271972-qhr6iir6	325	39	Unexpected	unexpected	JJ
cord-271972-qhr6iir6	325	40	roles	role	NNS
cord-271972-qhr6iir6	325	41	for	for	IN
cord-271972-qhr6iir6	325	42	UPF1	UPF1	NNP
cord-271972-qhr6iir6	325	43	in	in	IN
cord-271972-qhr6iir6	325	44	HIV-1	HIV-1	NNP
cord-271972-qhr6iir6	325	45	RNA	RNA	NNP
cord-271972-qhr6iir6	325	46	metabolism	metabolism	NN
cord-271972-qhr6iir6	325	47	and	and	CC
cord-271972-qhr6iir6	325	48	translation	translation	NN
cord-271972-qhr6iir6	325	49	Mechanism	Mechanism	NNP
cord-271972-qhr6iir6	325	50	of	of	IN
cord-271972-qhr6iir6	325	51	action	action	NN
cord-271972-qhr6iir6	325	52	of	of	IN
cord-271972-qhr6iir6	325	53	the	the	DT
cord-271972-qhr6iir6	325	54	toxic	toxic	JJ
cord-271972-qhr6iir6	325	55	lectin	lectin	NN
cord-271972-qhr6iir6	325	56	ricin	ricin	NN
cord-271972-qhr6iir6	325	57	on	on	IN
cord-271972-qhr6iir6	325	58	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	325	59	ribosomes	ribosome	NNS
cord-271972-qhr6iir6	325	60	A	a	DT
cord-271972-qhr6iir6	325	61	novel	novel	JJ
cord-271972-qhr6iir6	325	62	mechanism	mechanism	NN
cord-271972-qhr6iir6	325	63	for	for	IN
cord-271972-qhr6iir6	325	64	inhibition	inhibition	NN
cord-271972-qhr6iir6	325	65	of	of	IN
cord-271972-qhr6iir6	325	66	translation	translation	NN
cord-271972-qhr6iir6	325	67	by	by	IN
cord-271972-qhr6iir6	325	68	pokeweed	pokeweed	JJ
cord-271972-qhr6iir6	325	69	antiviral	antiviral	JJ
cord-271972-qhr6iir6	325	70	protein	protein	NN
cord-271972-qhr6iir6	325	71	:	:	:
cord-271972-qhr6iir6	325	72	depurination	depurination	NN
cord-271972-qhr6iir6	325	73	of	of	IN
cord-271972-qhr6iir6	325	74	the	the	DT
cord-271972-qhr6iir6	325	75	capped	cap	VBN
cord-271972-qhr6iir6	325	76	RNA	rna	NN
cord-271972-qhr6iir6	325	77	template	template	NN
cord-271972-qhr6iir6	325	78	Purification	purification	NN
cord-271972-qhr6iir6	325	79	and	and	CC
cord-271972-qhr6iir6	325	80	partial	partial	JJ
cord-271972-qhr6iir6	325	81	characterization	characterization	NN
cord-271972-qhr6iir6	325	82	of	of	IN
cord-271972-qhr6iir6	325	83	the	the	DT
cord-271972-qhr6iir6	325	84	antiviral	antiviral	JJ
cord-271972-qhr6iir6	325	85	protein	protein	NN
cord-271972-qhr6iir6	325	86	from	from	IN
cord-271972-qhr6iir6	325	87	Phytolacca	Phytolacca	NNP
cord-271972-qhr6iir6	325	88	americana	americana	NNP
cord-271972-qhr6iir6	325	89	which	which	WDT
cord-271972-qhr6iir6	325	90	inhibits	inhibit	VBZ
cord-271972-qhr6iir6	325	91	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	325	92	protein	protein	NN
cord-271972-qhr6iir6	325	93	synthesis	synthesis	NN
cord-271972-qhr6iir6	325	94	Inhibition	inhibition	NN
cord-271972-qhr6iir6	325	95	of	of	IN
cord-271972-qhr6iir6	325	96	HIV-1	HIV-1	NNP
cord-271972-qhr6iir6	325	97	replication	replication	NN
cord-271972-qhr6iir6	325	98	in	in	IN
cord-271972-qhr6iir6	325	99	seropositive	seropositive	JJ
cord-271972-qhr6iir6	325	100	patients	patient	NNS
cord-271972-qhr6iir6	325	101	'	'	POS
cord-271972-qhr6iir6	325	102	CD4	CD4	NNP
cord-271972-qhr6iir6	325	103	+	+	CC
cord-271972-qhr6iir6	325	104	T	t	NN
cord-271972-qhr6iir6	325	105	-	-	HYPH
cord-271972-qhr6iir6	325	106	cells	cell	NNS
cord-271972-qhr6iir6	325	107	by	by	IN
cord-271972-qhr6iir6	325	108	pokeweed	pokeweed	JJ
cord-271972-qhr6iir6	325	109	antiviral	antiviral	JJ
cord-271972-qhr6iir6	325	110	protein	protein	NN
cord-271972-qhr6iir6	325	111	-	-	HYPH
cord-271972-qhr6iir6	325	112	monoclonal	monoclonal	JJ
cord-271972-qhr6iir6	325	113	antibody	antibody	NN
cord-271972-qhr6iir6	325	114	conjugates	conjugate	VBZ
cord-271972-qhr6iir6	325	115	Antiviral	antiviral	JJ
cord-271972-qhr6iir6	325	116	activity	activity	NN
cord-271972-qhr6iir6	325	117	of	of	IN
cord-271972-qhr6iir6	325	118	ribosome	ribosome	NN
cord-271972-qhr6iir6	325	119	inactivating	inactivate	VBG
cord-271972-qhr6iir6	325	120	proteins	protein	NNS
cord-271972-qhr6iir6	325	121	in	in	IN
cord-271972-qhr6iir6	325	122	medicine	medicine	NN
cord-271972-qhr6iir6	325	123	C	c	NN
cord-271972-qhr6iir6	325	124	-	-	HYPH
cord-271972-qhr6iir6	325	125	terminal	terminal	NN
cord-271972-qhr6iir6	325	126	deletion	deletion	NN
cord-271972-qhr6iir6	325	127	mutant	mutant	NN
cord-271972-qhr6iir6	325	128	of	of	IN
cord-271972-qhr6iir6	325	129	pokeweed	pokeweed	JJ
cord-271972-qhr6iir6	325	130	antiviral	antiviral	JJ
cord-271972-qhr6iir6	325	131	protein	protein	NN
cord-271972-qhr6iir6	325	132	inhibits	inhibit	VBZ
cord-271972-qhr6iir6	325	133	viral	viral	JJ
cord-271972-qhr6iir6	325	134	infection	infection	NN
cord-271972-qhr6iir6	325	135	but	but	CC
cord-271972-qhr6iir6	325	136	does	do	VBZ
cord-271972-qhr6iir6	325	137	not	not	RB
cord-271972-qhr6iir6	325	138	depurinate	depurinate	NNP
cord-271972-qhr6iir6	325	139	host	host	NN
cord-271972-qhr6iir6	325	140	ribosomes	ribosome	NNS
cord-271972-qhr6iir6	325	141	Depurination	Depurination	NNP
cord-271972-qhr6iir6	325	142	of	of	IN
cord-271972-qhr6iir6	325	143	Brome	Brome	NNP
cord-271972-qhr6iir6	325	144	mosaic	mosaic	JJ
cord-271972-qhr6iir6	325	145	virus	virus	NN
cord-271972-qhr6iir6	325	146	RNA3	RNA3	NNP
cord-271972-qhr6iir6	325	147	in	in	IN
cord-271972-qhr6iir6	325	148	vivo	vivo	NN
cord-271972-qhr6iir6	325	149	results	result	NNS
cord-271972-qhr6iir6	325	150	in	in	IN
cord-271972-qhr6iir6	325	151	translation	translation	NN
cord-271972-qhr6iir6	325	152	-	-	HYPH
cord-271972-qhr6iir6	325	153	dependent	dependent	JJ
cord-271972-qhr6iir6	325	154	accelerated	accelerate	VBN
cord-271972-qhr6iir6	325	155	degradation	degradation	NN
cord-271972-qhr6iir6	325	156	of	of	IN
cord-271972-qhr6iir6	325	157	the	the	DT
cord-271972-qhr6iir6	325	158	viral	viral	JJ
cord-271972-qhr6iir6	325	159	RNA	RNA	NNP
cord-271972-qhr6iir6	325	160	Endonucleolytic	Endonucleolytic	NNP
cord-271972-qhr6iir6	325	161	cleavage	cleavage	NN
cord-271972-qhr6iir6	325	162	of	of	IN
cord-271972-qhr6iir6	325	163	eukaryotic	eukaryotic	JJ
cord-271972-qhr6iir6	325	164	mRNAs	mRNAs	NNPS
cord-271972-qhr6iir6	325	165	with	with	IN
cord-271972-qhr6iir6	325	166	stalls	stall	NNS
cord-271972-qhr6iir6	325	167	in	in	IN
cord-271972-qhr6iir6	325	168	translation	translation	NN
cord-271972-qhr6iir6	325	169	elongation	elongation	NN
cord-271972-qhr6iir6	325	170	Suppression	Suppression	NNP
cord-271972-qhr6iir6	325	171	of	of	IN
cord-271972-qhr6iir6	325	172	human	human	JJ
cord-271972-qhr6iir6	325	173	T	t	NN
cord-271972-qhr6iir6	325	174	-	-	HYPH
cord-271972-qhr6iir6	325	175	cell	cell	NN
cord-271972-qhr6iir6	325	176	leukemia	leukemia	NN
cord-271972-qhr6iir6	325	177	virus	virus	NN
cord-271972-qhr6iir6	326	1	I	-PRON-	PRP
cord-271972-qhr6iir6	326	2	gene	gene	NN
cord-271972-qhr6iir6	326	3	expression	expression	NN
cord-271972-qhr6iir6	326	4	by	by	IN
cord-271972-qhr6iir6	326	5	pokeweed	pokeweed	JJ
cord-271972-qhr6iir6	326	6	antiviral	antiviral	JJ
cord-271972-qhr6iir6	326	7	protein	protein	NN
cord-271972-qhr6iir6	326	8	Isolation	isolation	NN
cord-271972-qhr6iir6	326	9	and	and	CC
cord-271972-qhr6iir6	326	10	purification	purification	NN
cord-271972-qhr6iir6	326	11	of	of	IN
cord-271972-qhr6iir6	326	12	ribosome	ribosome	NN
cord-271972-qhr6iir6	326	13	-	-	HYPH
cord-271972-qhr6iir6	326	14	inactivating	inactivate	VBG
cord-271972-qhr6iir6	326	15	proteins	protein	NNS
cord-271972-qhr6iir6	327	1	Viral	viral	JJ
cord-271972-qhr6iir6	327	2	encounters	encounter	VBZ
cord-271972-qhr6iir6	327	3	with	with	IN
cord-271972-qhr6iir6	327	4	2	2	CD
cord-271972-qhr6iir6	327	5	,	,	,
cord-271972-qhr6iir6	327	6	5	5	CD
cord-271972-qhr6iir6	327	7	-oligoadenylate	-oligoadenylate	NN
cord-271972-qhr6iir6	327	8	synthetase	synthetase	NN
cord-271972-qhr6iir6	327	9	and	and	CC
cord-271972-qhr6iir6	327	10	RNase	RNase	NNP
cord-271972-qhr6iir6	327	11	L	L	NNP
cord-271972-qhr6iir6	327	12	during	during	IN
cord-271972-qhr6iir6	327	13	the	the	DT
cord-271972-qhr6iir6	327	14	interferon	interferon	NN
cord-271972-qhr6iir6	327	15	antiviral	antiviral	JJ
cord-271972-qhr6iir6	327	16	response	response	NN
cord-271972-qhr6iir6	327	17	Small	small	JJ
cord-271972-qhr6iir6	327	18	self	self	NN
cord-271972-qhr6iir6	327	19	-	-	HYPH
cord-271972-qhr6iir6	327	20	RNA	RNA	NNP
cord-271972-qhr6iir6	327	21	generated	generate	VBN
cord-271972-qhr6iir6	327	22	by	by	IN
cord-271972-qhr6iir6	327	23	RNase	RNase	NNP
cord-271972-qhr6iir6	327	24	L	L	NNP
cord-271972-qhr6iir6	327	25	amplifies	amplify	VBZ
cord-271972-qhr6iir6	327	26	antiviral	antiviral	JJ
cord-271972-qhr6iir6	327	27	innate	innate	JJ
cord-271972-qhr6iir6	327	28	immunity	immunity	NN
cord-271972-qhr6iir6	327	29	Interferon	Interferon	NNP
cord-271972-qhr6iir6	327	30	action	action	NN
cord-271972-qhr6iir6	327	31	and	and	CC
cord-271972-qhr6iir6	327	32	apoptosis	apoptosis	NN
cord-271972-qhr6iir6	327	33	are	be	VBP
cord-271972-qhr6iir6	327	34	defective	defective	JJ
cord-271972-qhr6iir6	327	35	in	in	IN
cord-271972-qhr6iir6	327	36	mice	mice	NN
cord-271972-qhr6iir6	327	37	devoid	devoid	JJ
cord-271972-qhr6iir6	327	38	of	of	IN
cord-271972-qhr6iir6	327	39	2	2	CD
cord-271972-qhr6iir6	327	40	,	,	,
cord-271972-qhr6iir6	327	41	5	5	CD
cord-271972-qhr6iir6	327	42	-oligoadenylate	-oligoadenylate	HYPH
cord-271972-qhr6iir6	327	43	-	-	HYPH
cord-271972-qhr6iir6	327	44	dependent	dependent	JJ
cord-271972-qhr6iir6	327	45	RNase	rnase	NN
cord-271972-qhr6iir6	327	46	L	L	NNP
cord-271972-qhr6iir6	327	47	Alphavirus	Alphavirus	NNP
cord-271972-qhr6iir6	327	48	minus	minus	JJ
cord-271972-qhr6iir6	327	49	-	-	HYPH
cord-271972-qhr6iir6	327	50	strand	strand	NN
cord-271972-qhr6iir6	327	51	synthesis	synthesis	NN
cord-271972-qhr6iir6	327	52	and	and	CC
cord-271972-qhr6iir6	327	53	persistence	persistence	NN
cord-271972-qhr6iir6	327	54	in	in	IN
cord-271972-qhr6iir6	327	55	mouse	mouse	NN
cord-271972-qhr6iir6	327	56	embryo	embryo	NN
cord-271972-qhr6iir6	327	57	fibroblasts	fibroblast	NNS
cord-271972-qhr6iir6	327	58	derived	derive	VBN
cord-271972-qhr6iir6	327	59	from	from	IN
cord-271972-qhr6iir6	327	60	mice	mouse	NNS
cord-271972-qhr6iir6	327	61	lacking	lack	VBG
cord-271972-qhr6iir6	327	62	RNase	RNase	NNP
cord-271972-qhr6iir6	327	63	L	l	NN
cord-271972-qhr6iir6	327	64	and	and	CC
cord-271972-qhr6iir6	327	65	protein	protein	NN
cord-271972-qhr6iir6	327	66	kinase	kinase	NN
cord-271972-qhr6iir6	327	67	R	r	NN
cord-271972-qhr6iir6	327	68	RNase	rnase	NN
cord-271972-qhr6iir6	327	69	L	l	NN
cord-271972-qhr6iir6	327	70	and	and	CC
cord-271972-qhr6iir6	327	71	double	double	RB
cord-271972-qhr6iir6	327	72	-	-	HYPH
cord-271972-qhr6iir6	327	73	stranded	strand	VBN
cord-271972-qhr6iir6	327	74	RNA	rna	NN
cord-271972-qhr6iir6	327	75	-	-	HYPH
cord-271972-qhr6iir6	327	76	dependent	dependent	JJ
cord-271972-qhr6iir6	327	77	protein	protein	NN
cord-271972-qhr6iir6	327	78	kinase	kinase	NN
cord-271972-qhr6iir6	327	79	exert	exert	VBP
cord-271972-qhr6iir6	327	80	complementary	complementary	JJ
cord-271972-qhr6iir6	327	81	roles	role	NNS
cord-271972-qhr6iir6	327	82	in	in	IN
cord-271972-qhr6iir6	327	83	islet	islet	NN
cord-271972-qhr6iir6	327	84	cell	cell	NN
cord-271972-qhr6iir6	327	85	defense	defense	NN
cord-271972-qhr6iir6	327	86	during	during	IN
cord-271972-qhr6iir6	327	87	coxsackievirus	coxsackievirus	NNP
cord-271972-qhr6iir6	327	88	infection	infection	NN
cord-271972-qhr6iir6	327	89	Detection	Detection	NNP
cord-271972-qhr6iir6	327	90	of	of	IN
cord-271972-qhr6iir6	327	91	an	an	DT
cord-271972-qhr6iir6	327	92	infectious	infectious	JJ
cord-271972-qhr6iir6	327	93	retrovirus	retrovirus	NN
cord-271972-qhr6iir6	327	94	,	,	,
cord-271972-qhr6iir6	327	95	XMRV	XMRV	NNP
cord-271972-qhr6iir6	327	96	,	,	,
cord-271972-qhr6iir6	327	97	in	in	IN
cord-271972-qhr6iir6	327	98	blood	blood	NN
cord-271972-qhr6iir6	327	99	cells	cell	NNS
cord-271972-qhr6iir6	327	100	of	of	IN
cord-271972-qhr6iir6	327	101	patients	patient	NNS
cord-271972-qhr6iir6	327	102	with	with	IN
cord-271972-qhr6iir6	327	103	chronic	chronic	JJ
cord-271972-qhr6iir6	327	104	fatigue	fatigue	NN
cord-271972-qhr6iir6	327	105	syndrome	syndrome	NN
cord-271972-qhr6iir6	327	106	Identification	identification	NN
cord-271972-qhr6iir6	327	107	of	of	IN
cord-271972-qhr6iir6	327	108	a	a	DT
cord-271972-qhr6iir6	327	109	novel	novel	NN
cord-271972-qhr6iir6	327	110	Gammaretrovirus	Gammaretrovirus	NNP
cord-271972-qhr6iir6	327	111	in	in	IN
cord-271972-qhr6iir6	327	112	prostate	prostate	NN
cord-271972-qhr6iir6	327	113	tumors	tumor	NNS
cord-271972-qhr6iir6	327	114	of	of	IN
cord-271972-qhr6iir6	327	115	patients	patient	NNS
cord-271972-qhr6iir6	327	116	homozygous	homozygous	JJ
cord-271972-qhr6iir6	327	117	for	for	IN
cord-271972-qhr6iir6	327	118	R462Q	R462Q	NNP
cord-271972-qhr6iir6	327	119	RNASEL	RNASEL	NNP
cord-271972-qhr6iir6	327	120	variant	variant	NN
cord-271972-qhr6iir6	327	121	RNase	RNase	NNP
cord-271972-qhr6iir6	327	122	L	L	NNP
cord-271972-qhr6iir6	327	123	mediated	mediate	VBD
cord-271972-qhr6iir6	327	124	protection	protection	NN
cord-271972-qhr6iir6	327	125	from	from	IN
cord-271972-qhr6iir6	327	126	virus	virus	NN
cord-271972-qhr6iir6	327	127	induced	induce	VBN
cord-271972-qhr6iir6	327	128	demyelination	demyelination	NN
cord-271972-qhr6iir6	328	1	The	the	DT
cord-271972-qhr6iir6	328	2	multifunctional	multifunctional	JJ
cord-271972-qhr6iir6	328	3	NS1	ns1	NN
cord-271972-qhr6iir6	328	4	protein	protein	NN
cord-271972-qhr6iir6	328	5	of	of	IN
cord-271972-qhr6iir6	328	6	influenza	influenza	NN
cord-271972-qhr6iir6	328	7	A	a	DT
cord-271972-qhr6iir6	328	8	viruses	virus	NNS
cord-271972-qhr6iir6	329	1	The	the	DT
cord-271972-qhr6iir6	329	2	primary	primary	JJ
cord-271972-qhr6iir6	329	3	function	function	NN
cord-271972-qhr6iir6	329	4	of	of	IN
cord-271972-qhr6iir6	329	5	RNA	RNA	NNP
cord-271972-qhr6iir6	329	6	binding	bind	VBG
cord-271972-qhr6iir6	329	7	by	by	IN
cord-271972-qhr6iir6	329	8	the	the	DT
cord-271972-qhr6iir6	329	9	influenza	influenza	NN
cord-271972-qhr6iir6	329	10	A	a	DT
cord-271972-qhr6iir6	329	11	virus	virus	NN
cord-271972-qhr6iir6	329	12	NS1	ns1	CD
cord-271972-qhr6iir6	329	13	protein	protein	NN
cord-271972-qhr6iir6	329	14	in	in	IN
cord-271972-qhr6iir6	329	15	infected	infected	JJ
cord-271972-qhr6iir6	329	16	cells	cell	NNS
cord-271972-qhr6iir6	329	17	:	:	:
cord-271972-qhr6iir6	329	18	inhibiting	inhibit	VBG
cord-271972-qhr6iir6	329	19	the	the	DT
cord-271972-qhr6iir6	329	20	2	2	CD
cord-271972-qhr6iir6	329	21	-5	-5	CD
cord-271972-qhr6iir6	329	22	oligo	oligo	NNP
cord-271972-qhr6iir6	329	23	(	(	-LRB-
cord-271972-qhr6iir6	329	24	A	a	NN
cord-271972-qhr6iir6	329	25	)	)	-RRB-
cord-271972-qhr6iir6	329	26	synthetase	synthetase	NN
cord-271972-qhr6iir6	329	27	/	/	SYM
cord-271972-qhr6iir6	329	28	RNase	rnase	NN
cord-271972-qhr6iir6	329	29	L	L	NNP
cord-271972-qhr6iir6	329	30	pathway	pathway	NN
cord-271972-qhr6iir6	329	31	Mechanisms	mechanism	NNS
cord-271972-qhr6iir6	329	32	employed	employ	VBN
cord-271972-qhr6iir6	329	33	by	by	IN
cord-271972-qhr6iir6	329	34	retroviruses	retrovirus	NNS
cord-271972-qhr6iir6	329	35	to	to	TO
cord-271972-qhr6iir6	329	36	exploit	exploit	VB
cord-271972-qhr6iir6	329	37	host	host	NN
cord-271972-qhr6iir6	329	38	factors	factor	NNS
cord-271972-qhr6iir6	329	39	for	for	IN
cord-271972-qhr6iir6	329	40	translational	translational	JJ
cord-271972-qhr6iir6	329	41	control	control	NN
cord-271972-qhr6iir6	329	42	of	of	IN
cord-271972-qhr6iir6	329	43	a	a	DT
cord-271972-qhr6iir6	329	44	complicated	complicated	JJ
cord-271972-qhr6iir6	329	45	proteome	proteome	NN
cord-271972-qhr6iir6	329	46	2	2	CD
cord-271972-qhr6iir6	329	47	-	-	HYPH
cord-271972-qhr6iir6	329	48	5A	5a	NN
cord-271972-qhr6iir6	329	49	accumulates	accumulate	VBZ
cord-271972-qhr6iir6	329	50	to	to	IN
cord-271972-qhr6iir6	329	51	high	high	JJ
cord-271972-qhr6iir6	329	52	levels	level	NNS
cord-271972-qhr6iir6	329	53	in	in	IN
cord-271972-qhr6iir6	329	54	interferon	interferon	NN
cord-271972-qhr6iir6	329	55	-	-	HYPH
cord-271972-qhr6iir6	329	56	treated	treat	VBN
cord-271972-qhr6iir6	329	57	,	,	,
cord-271972-qhr6iir6	329	58	vaccinia	vaccinia	NN
cord-271972-qhr6iir6	329	59	virusinfected	virusinfecte	VBN
cord-271972-qhr6iir6	329	60	cells	cell	NNS
cord-271972-qhr6iir6	329	61	in	in	IN
cord-271972-qhr6iir6	329	62	the	the	DT
cord-271972-qhr6iir6	329	63	absence	absence	NN
cord-271972-qhr6iir6	329	64	of	of	IN
cord-271972-qhr6iir6	329	65	any	any	DT
cord-271972-qhr6iir6	329	66	inhibition	inhibition	NN
cord-271972-qhr6iir6	329	67	of	of	IN
cord-271972-qhr6iir6	329	68	virus	virus	NN
cord-271972-qhr6iir6	329	69	replication	replication	NN
cord-271972-qhr6iir6	329	70	Activation	activation	NN
cord-271972-qhr6iir6	329	71	and	and	CC
cord-271972-qhr6iir6	329	72	evasion	evasion	NN
cord-271972-qhr6iir6	329	73	of	of	IN
cord-271972-qhr6iir6	329	74	the	the	DT
cord-271972-qhr6iir6	329	75	antiviral	antiviral	JJ
cord-271972-qhr6iir6	329	76	2	2	CD
cord-271972-qhr6iir6	329	77	-5	-5	NNP
cord-271972-qhr6iir6	329	78	oligoadenylate	oligoadenylate	NNP
cord-271972-qhr6iir6	329	79	synthetase	synthetase	NN
cord-271972-qhr6iir6	329	80	/	/	SYM
cord-271972-qhr6iir6	329	81	ribonuclease	ribonuclease	NN
cord-271972-qhr6iir6	329	82	L	L	NNP
cord-271972-qhr6iir6	329	83	pathway	pathway	NN
cord-271972-qhr6iir6	329	84	by	by	IN
cord-271972-qhr6iir6	329	85	hepatitis	hepatitis	NN
cord-271972-qhr6iir6	329	86	C	C	NNP
cord-271972-qhr6iir6	329	87	virus	virus	NN
cord-271972-qhr6iir6	330	1	mRNA	mRNA	NNP
cord-271972-qhr6iir6	331	1	A	a	DT
cord-271972-qhr6iir6	331	2	phylogenetically	phylogenetically	RB
cord-271972-qhr6iir6	331	3	conserved	conserve	VBN
cord-271972-qhr6iir6	331	4	RNA	RNA	NNP
cord-271972-qhr6iir6	331	5	structure	structure	NN
cord-271972-qhr6iir6	331	6	in	in	IN
cord-271972-qhr6iir6	331	7	the	the	DT
cord-271972-qhr6iir6	331	8	poliovirus	poliovirus	NN
cord-271972-qhr6iir6	331	9	open	open	JJ
cord-271972-qhr6iir6	331	10	reading	reading	NN
cord-271972-qhr6iir6	331	11	frame	frame	NN
cord-271972-qhr6iir6	331	12	inhibits	inhibit	VBZ
cord-271972-qhr6iir6	331	13	the	the	DT
cord-271972-qhr6iir6	331	14	antiviral	antiviral	JJ
cord-271972-qhr6iir6	331	15	endoribonuclease	endoribonuclease	NN
cord-271972-qhr6iir6	332	1	RNase	RNase	NNP
cord-271972-qhr6iir6	332	2	L	L	NNP
cord-271972-qhr6iir6	332	3	A	A	NNP
cord-271972-qhr6iir6	332	4	viral	viral	JJ
cord-271972-qhr6iir6	332	5	RNA	rna	NN
cord-271972-qhr6iir6	332	6	competitively	competitively	RB
cord-271972-qhr6iir6	332	7	inhibits	inhibit	VBZ
cord-271972-qhr6iir6	332	8	the	the	DT
cord-271972-qhr6iir6	332	9	antiviral	antiviral	JJ
cord-271972-qhr6iir6	332	10	endoribonuclease	endoribonuclease	NN
cord-271972-qhr6iir6	332	11	domain	domain	NN
cord-271972-qhr6iir6	332	12	of	of	IN
cord-271972-qhr6iir6	332	13	RNase	RNase	NNP
cord-271972-qhr6iir6	332	14	L	L	NNP
cord-271972-qhr6iir6	332	15	Involvement	Involvement	NNP
cord-271972-qhr6iir6	332	16	of	of	IN
cord-271972-qhr6iir6	332	17	the	the	DT
cord-271972-qhr6iir6	332	18	interferonregulated	interferonregulate	VBN
cord-271972-qhr6iir6	332	19	antiviral	antiviral	JJ
cord-271972-qhr6iir6	332	20	proteins	protein	NNS
cord-271972-qhr6iir6	332	21	PKR	PKR	NNP
cord-271972-qhr6iir6	332	22	and	and	CC
cord-271972-qhr6iir6	332	23	RNase	RNase	NNP
cord-271972-qhr6iir6	332	24	L	L	NNP
cord-271972-qhr6iir6	332	25	in	in	IN
cord-271972-qhr6iir6	332	26	reovirus	reovirus	NNP
cord-271972-qhr6iir6	332	27	-	-	HYPH
cord-271972-qhr6iir6	332	28	induced	induce	VBN
cord-271972-qhr6iir6	332	29	shutoff	shutoff	NN
cord-271972-qhr6iir6	332	30	of	of	IN
cord-271972-qhr6iir6	332	31	cellular	cellular	JJ
cord-271972-qhr6iir6	332	32	translation	translation	NN
cord-271972-qhr6iir6	333	1	The	the	DT
cord-271972-qhr6iir6	333	2	2	2	CD
cord-271972-qhr6iir6	333	3	-5	-5	CD
cord-271972-qhr6iir6	333	4	oligoadenylate	oligoadenylate	NNP
cord-271972-qhr6iir6	333	5	/	/	SYM
cord-271972-qhr6iir6	333	6	RNase	RNase	NNP
cord-271972-qhr6iir6	333	7	L	L	NNP
cord-271972-qhr6iir6	333	8	/	/	SYM
cord-271972-qhr6iir6	333	9	RNase	RNase	NNP
cord-271972-qhr6iir6	333	10	L	L	NNP
cord-271972-qhr6iir6	333	11	inhibitor	inhibitor	NN
cord-271972-qhr6iir6	333	12	pathway	pathway	NN
cord-271972-qhr6iir6	333	13	regulates	regulate	VBZ
cord-271972-qhr6iir6	333	14	both	both	CC
cord-271972-qhr6iir6	333	15	MyoD	MyoD	NNP
cord-271972-qhr6iir6	333	16	mRNA	mrna	NN
cord-271972-qhr6iir6	333	17	stability	stability	NN
cord-271972-qhr6iir6	333	18	and	and	CC
cord-271972-qhr6iir6	333	19	muscle	muscle	NN
cord-271972-qhr6iir6	333	20	cell	cell	NN
cord-271972-qhr6iir6	333	21	differentiation	differentiation	NN
cord-271972-qhr6iir6	334	1	RNase	RNase	NNP
cord-271972-qhr6iir6	334	2	L	L	NNP
cord-271972-qhr6iir6	334	3	mediates	mediate	VBZ
cord-271972-qhr6iir6	334	4	transient	transient	JJ
cord-271972-qhr6iir6	334	5	control	control	NN
cord-271972-qhr6iir6	334	6	of	of	IN
cord-271972-qhr6iir6	334	7	the	the	DT
cord-271972-qhr6iir6	334	8	interferon	interferon	NN
cord-271972-qhr6iir6	334	9	response	response	NN
cord-271972-qhr6iir6	334	10	through	through	IN
cord-271972-qhr6iir6	334	11	modulation	modulation	NN
cord-271972-qhr6iir6	334	12	of	of	IN
cord-271972-qhr6iir6	334	13	the	the	DT
cord-271972-qhr6iir6	334	14	double	double	RB
cord-271972-qhr6iir6	334	15	-	-	HYPH
cord-271972-qhr6iir6	334	16	stranded	strand	VBN
cord-271972-qhr6iir6	334	17	RNA	rna	NN
cord-271972-qhr6iir6	334	18	-	-	HYPH
cord-271972-qhr6iir6	334	19	dependent	dependent	JJ
cord-271972-qhr6iir6	334	20	protein	protein	NN
cord-271972-qhr6iir6	334	21	kinase	kinase	VBZ
cord-271972-qhr6iir6	334	22	PKR	PKR	NNP
cord-271972-qhr6iir6	334	23	RNase	RNase	NNP
cord-271972-qhr6iir6	334	24	-	-	HYPH
cord-271972-qhr6iir6	334	25	L	l	NN
cord-271972-qhr6iir6	334	26	-	-	HYPH
cord-271972-qhr6iir6	334	27	dependent	dependent	JJ
cord-271972-qhr6iir6	334	28	destabilization	destabilization	NN
cord-271972-qhr6iir6	334	29	of	of	IN
cord-271972-qhr6iir6	334	30	interferoninduced	interferoninduced	NNP
cord-271972-qhr6iir6	334	31	mRNAs	mrnas	CD
cord-271972-qhr6iir6	334	32	.	.	.
cord-271972-qhr6iir6	335	1	A	a	DT
cord-271972-qhr6iir6	335	2	role	role	NN
cord-271972-qhr6iir6	335	3	for	for	IN
cord-271972-qhr6iir6	335	4	the	the	DT
cord-271972-qhr6iir6	335	5	2	2	CD
cord-271972-qhr6iir6	335	6	-	-	HYPH
cord-271972-qhr6iir6	335	7	5A	5a	CD
cord-271972-qhr6iir6	335	8	system	system	NN
cord-271972-qhr6iir6	335	9	in	in	IN
cord-271972-qhr6iir6	335	10	attenuation	attenuation	NN
cord-271972-qhr6iir6	335	11	of	of	IN
cord-271972-qhr6iir6	335	12	the	the	DT
cord-271972-qhr6iir6	335	13	interferon	interferon	NN
cord-271972-qhr6iir6	335	14	response	response	NN
cord-271972-qhr6iir6	335	15	Preferential	preferential	JJ
cord-271972-qhr6iir6	335	16	translation	translation	NN
cord-271972-qhr6iir6	335	17	of	of	IN
cord-271972-qhr6iir6	335	18	reovirus	reovirus	NNP
cord-271972-qhr6iir6	335	19	mRNA	mRNA	NNP
cord-271972-qhr6iir6	335	20	by	by	IN
cord-271972-qhr6iir6	335	21	a	a	DT
cord-271972-qhr6iir6	335	22	sigma3-dependent	sigma3-dependent	NN
cord-271972-qhr6iir6	335	23	mechanism	mechanism	NN
cord-271972-qhr6iir6	335	24	Synthesis	Synthesis	NNP
cord-271972-qhr6iir6	335	25	of	of	IN
cord-271972-qhr6iir6	335	26	(	(	-LRB-
cord-271972-qhr6iir6	335	27	2	2	CD
cord-271972-qhr6iir6	335	28	-5	-5	NNP
cord-271972-qhr6iir6	335	29	)	)	-RRB-
cord-271972-qhr6iir6	335	30	oligoadenylate	oligoadenylate	NN
cord-271972-qhr6iir6	335	31	and	and	CC
cord-271972-qhr6iir6	335	32	activation	activation	NN
cord-271972-qhr6iir6	335	33	of	of	IN
cord-271972-qhr6iir6	335	34	an	an	DT
cord-271972-qhr6iir6	335	35	endoribonuclease	endoribonuclease	NN
cord-271972-qhr6iir6	335	36	in	in	IN
cord-271972-qhr6iir6	335	37	interferon	interferon	NN
cord-271972-qhr6iir6	335	38	-	-	HYPH
cord-271972-qhr6iir6	335	39	treated	treat	VBN
cord-271972-qhr6iir6	335	40	HeLa	HeLa	NNP
cord-271972-qhr6iir6	335	41	cells	cell	NNS
cord-271972-qhr6iir6	335	42	infected	infect	VBN
cord-271972-qhr6iir6	335	43	with	with	IN
cord-271972-qhr6iir6	335	44	reovirus	reovirus	NNP
cord-271972-qhr6iir6	335	45	The	the	DT
cord-271972-qhr6iir6	335	46	molecular	molecular	JJ
cord-271972-qhr6iir6	335	47	basis	basis	NN
cord-271972-qhr6iir6	335	48	of	of	IN
cord-271972-qhr6iir6	335	49	viral	viral	JJ
cord-271972-qhr6iir6	335	50	oncolysis	oncolysis	NN
cord-271972-qhr6iir6	335	51	:	:	:
cord-271972-qhr6iir6	335	52	usurpation	usurpation	NN
cord-271972-qhr6iir6	335	53	of	of	IN
cord-271972-qhr6iir6	335	54	the	the	DT
cord-271972-qhr6iir6	335	55	Ras	Ras	NNP
cord-271972-qhr6iir6	335	56	signaling	signal	VBG
cord-271972-qhr6iir6	335	57	pathway	pathway	NN
cord-271972-qhr6iir6	335	58	by	by	IN
cord-271972-qhr6iir6	335	59	reovirus	reovirus	NNP
cord-271972-qhr6iir6	335	60	Influenza	Influenza	NNP
cord-271972-qhr6iir6	335	61	A	A	NNP
cord-271972-qhr6iir6	336	1	virus	virus	NN
cord-271972-qhr6iir6	336	2	NS1	NS1	NNP
cord-271972-qhr6iir6	336	3	protein	protein	NN
cord-271972-qhr6iir6	336	4	targets	target	NNS
cord-271972-qhr6iir6	337	1	poly(A)-binding	poly(A)-binding	NNP
cord-271972-qhr6iir6	338	1	protein	protein	NNP
cord-271972-qhr6iir6	338	2	II	II	NNP
cord-271972-qhr6iir6	338	3	of	of	IN
cord-271972-qhr6iir6	338	4	the	the	DT
cord-271972-qhr6iir6	338	5	cellular	cellular	JJ
cord-271972-qhr6iir6	338	6	3	3	CD
cord-271972-qhr6iir6	338	7	-end	-end	SYM
cord-271972-qhr6iir6	338	8	processing	process	VBG
cord-271972-qhr6iir6	338	9	machinery	machinery	NN
cord-271972-qhr6iir6	339	1	The	the	DT
cord-271972-qhr6iir6	339	2	cap	cap	NN
cord-271972-qhr6iir6	339	3	-	-	HYPH
cord-271972-qhr6iir6	339	4	snatching	snatch	VBG
cord-271972-qhr6iir6	339	5	endonuclease	endonuclease	NN
cord-271972-qhr6iir6	339	6	of	of	IN
cord-271972-qhr6iir6	339	7	influenza	influenza	NN
cord-271972-qhr6iir6	339	8	virus	virus	NN
cord-271972-qhr6iir6	339	9	polymerase	polymerase	NN
cord-271972-qhr6iir6	339	10	resides	reside	VBZ
cord-271972-qhr6iir6	339	11	in	in	IN
cord-271972-qhr6iir6	339	12	the	the	DT
cord-271972-qhr6iir6	339	13	PA	PA	NNP
cord-271972-qhr6iir6	339	14	subunit	subunit	NN
cord-271972-qhr6iir6	339	15	A	a	DT
cord-271972-qhr6iir6	339	16	two	two	CD
cord-271972-qhr6iir6	339	17	-	-	HYPH
cord-271972-qhr6iir6	339	18	pronged	pronged	JJ
cord-271972-qhr6iir6	339	19	strategy	strategy	NN
cord-271972-qhr6iir6	339	20	to	to	TO
cord-271972-qhr6iir6	339	21	suppress	suppress	VB
cord-271972-qhr6iir6	339	22	host	host	NN
cord-271972-qhr6iir6	339	23	protein	protein	NN
cord-271972-qhr6iir6	339	24	synthesis	synthesis	NN
cord-271972-qhr6iir6	339	25	by	by	IN
cord-271972-qhr6iir6	339	26	SARS	SARS	NNP
cord-271972-qhr6iir6	339	27	coronavirus	coronavirus	NN
cord-271972-qhr6iir6	340	1	Nsp1	nsp1	NN
cord-271972-qhr6iir6	340	2	protein	protein	NN
cord-271972-qhr6iir6	340	3	Functional	functional	JJ
cord-271972-qhr6iir6	340	4	interplay	interplay	NN
cord-271972-qhr6iir6	340	5	between	between	IN
cord-271972-qhr6iir6	340	6	viral	viral	JJ
cord-271972-qhr6iir6	340	7	and	and	CC
cord-271972-qhr6iir6	340	8	cellular	cellular	JJ
cord-271972-qhr6iir6	340	9	SR	SR	NNP
cord-271972-qhr6iir6	340	10	proteins	protein	NNS
cord-271972-qhr6iir6	340	11	in	in	IN
cord-271972-qhr6iir6	340	12	control	control	NN
cord-271972-qhr6iir6	340	13	of	of	IN
cord-271972-qhr6iir6	340	14	post	post	JJ
cord-271972-qhr6iir6	340	15	-	-	JJ
cord-271972-qhr6iir6	340	16	transcriptional	transcriptional	JJ
cord-271972-qhr6iir6	340	17	gene	gene	NN
cord-271972-qhr6iir6	340	18	regulation	regulation	NN
cord-271972-qhr6iir6	341	1	We	-PRON-	PRP
cord-271972-qhr6iir6	341	2	thank	thank	VBP
cord-271972-qhr6iir6	341	3	all	all	DT
cord-271972-qhr6iir6	341	4	members	member	NNS
cord-271972-qhr6iir6	341	5	of	of	IN
cord-271972-qhr6iir6	341	6	the	the	DT
cord-271972-qhr6iir6	341	7	Glaunsinger	Glaunsinger	NNP
cord-271972-qhr6iir6	341	8	lab	lab	NN
cord-271972-qhr6iir6	341	9	for	for	IN
cord-271972-qhr6iir6	341	10	helpful	helpful	JJ
cord-271972-qhr6iir6	341	11	discussions	discussion	NNS
cord-271972-qhr6iir6	341	12	and	and	CC
cord-271972-qhr6iir6	341	13	critical	critical	JJ
cord-271972-qhr6iir6	341	14	reading	reading	NN
cord-271972-qhr6iir6	341	15	of	of	IN
cord-271972-qhr6iir6	341	16	the	the	DT
cord-271972-qhr6iir6	341	17	manuscript	manuscript	NN
cord-271972-qhr6iir6	341	18	.	.	.
cord-271972-qhr6iir6	342	1	Funding	fund	VBG
cord-271972-qhr6iir6	342	2	to	to	IN
cord-271972-qhr6iir6	342	3	B.G.	B.G.	NNP
cord-271972-qhr6iir6	342	4	was	be	VBD
cord-271972-qhr6iir6	342	5	provided	provide	VBN
cord-271972-qhr6iir6	342	6	by	by	IN
cord-271972-qhr6iir6	342	7	a	a	DT
cord-271972-qhr6iir6	342	8	Burroughs	Burroughs	NNP
cord-271972-qhr6iir6	342	9	Wellcome	Wellcome	NNP
cord-271972-qhr6iir6	342	10	Foundation	Foundation	NNP
cord-271972-qhr6iir6	342	11	Investigators	Investigators	NNPS
cord-271972-qhr6iir6	342	12	in	in	IN
cord-271972-qhr6iir6	342	13	the	the	DT
cord-271972-qhr6iir6	342	14	Pathogenesis	Pathogenesis	NNP
cord-271972-qhr6iir6	342	15	of	of	IN
cord-271972-qhr6iir6	342	16	Infectious	Infectious	NNP
cord-271972-qhr6iir6	342	17	Disease	Disease	NNP
cord-271972-qhr6iir6	342	18	award	award	NN
cord-271972-qhr6iir6	342	19	.	.	.