id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-342649-ysossker	Scagnolari, Carolina	Evaluation of viral load in infants hospitalized with bronchiolitis caused by respiratory syncytial virus	2012-03-10		.txt	text/plain	3759	161	42	The relationship between viral load, disease severity and antiviral immune activation in infants suffering from respiratory syncytial virus (RSV)-associated bronchiolitis has not been well identified. The main objective of this study was to determine the existence of a correlation between RSV load and disease severity and also between different clinical markers and mRNA levels of the interferon stimulated gene (ISG)56 in infants hospitalized for bronchiolitis. Results indicated that viral load was positively related to the clinical severity of bronchiolitis, the length of hospital stay, the levels of glycemia and the relative gene expression of ISG56, whereas an inverse correlation was observed with the levels of hemoglobin. In the framework of a study aimed at understanding the pathogenesis of RSV infection and at further characterizing viral and host factors involved in determining the severity of bronchiolitis, we addressed whether any diVerences in RSV-RNA levels in the airway tracts of infants with bronchiolitis might explain the broad clinical spectrum of RSVassociated bronchiolitis.	./cache/cord-342649-ysossker.txt	./txt/cord-342649-ysossker.txt