id author title date pages extension mime words sentences flesch summary cache txt cord-340189-jo38hjqa Bar-On, Yinon M SARS-CoV-2 (COVID-19) by the numbers 2020-04-02 .txt text/plain 7246 458 58 If you are infectious for 4 days, then you will infect four others on average, which is on the high end of the R 0 values for SARS-CoV-2 in the absence of physical distancing. Assuming entry of the virus to the cells is rapid (we estimate 10 min for SARS-CoV-2), the time it takes to produce progeny can be estimated by quantifying the lag between inoculation and the appearance of new intracellular virions, also known as the 'eclipse period'. While both the time to complete a replication cycle and the burst size may vary significantly in an animal host due to factors including the type of cell infected or the action of the immune system, these numbers provide us with an approximate quantitative view of the viral life-cycle at the cellular level. (Hirano et al., 1976) : "The average per-cell yield of active virus was estimated to be about 6-7 Â 10 2 plaque-forming units." This data is for MHV, so more research is needed to verify these values for SARS-CoV-2. ./cache/cord-340189-jo38hjqa.txt ./txt/cord-340189-jo38hjqa.txt