id author title date pages extension mime words sentences flesch summary cache txt cord-327518-yilv9z2m nan Coronaviridae 2011-11-23 .txt text/plain 7123 351 49 In coronaviruses, proteolytic processing results in the production of 15 (in viruses belonging to the species Avian coronavirus) or 16 mature products, commonly referred to as non-structural proteins (nsp's) and numbered according to their position -from N-to C-terminus -in the viral polyproteins ( Figure 1 ). Apart from their relatively close phylogenetic relationship, the only general characteristics that would set them apart from other coronaviruses are (i) a unique type of nsp1, distinct in size and sequence from betacoronavirus nsp1 and without apparent counterpart in the gammacoronaviruses, and (ii) the presence of a commonly-shared accessory gene (designated ORF3 in most alphacoronavirus species, ORF3b and 3c in TGEV and in FCoV/CCoV, respectively) for a dispensable multi-spanning alphacoronavirus membrane protein (αmp). The structural proteins are expressed from three sg mRNA species that are 3 co-terminal with the genome and believed to be produced via a process of discontinuous minus-strand RNA synthesis similar to that of coronaviruses ( Figure 12 ). ./cache/cord-327518-yilv9z2m.txt ./txt/cord-327518-yilv9z2m.txt