id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-301904-mjfbvl5n	Schultz-Cherry, S.	Astroviruses	2014-11-28		.txt	text/plain	5493	270	39	Astrovirus as a cause of hospital-acquired viral diarrhea in young children is second only to rotavirus and norovirus, occurring at rates of 4.5-6%, and, in some studies, surpasses rotavirus in rates of nosocomial infections. Recent studies reported that an HAstV-VA1-like strain was detected in a patient with new-onset celiac disease and associated with extra-intestinal dissemination (including neural tissue) in immunocompromised children. Given the susceptibility of different cell lines for HAstV infection (depending on the serotype and genotype) it is possible that astroviruses use a variety of attachment proteins or receptors including carbohydrate moieties. The immunological response to astrovirus infection is poorly defined; however, observations in humans and animal models suggest that both the adaptive and innate responses play important roles in controlling and eliminating the virus. While astrovirus antibodies protected individuals from symptoms associated with infection, virus was identified in the feces, suggesting that such antibodies do not necessarily prevent viral replication.	./cache/cord-301904-mjfbvl5n.txt	./txt/cord-301904-mjfbvl5n.txt