id author title date pages extension mime words sentences flesch summary cache txt cord-298820-nogoqyxl Zhang, Qi Transcriptome altered by latent human cytomegalovirus infection on THP-1 cells using RNA-seq 2016-12-05 .txt text/plain 4670 261 45 Here, we profiled the expression of mRNAs and long noncoding RNAs (lncRNAs) in THP-1 cells using the emerging RNA-seq to investigate the transcriptional changes during HCMV latent infection. These studies identified a subset of differently expressed genes, which are involved in a variety of biological functions including innate immunity response, inflammation pathway, cell cycle regulation, cellular metabolism and cell adhesion, during lytic HCMV infection. The present study adopted RNA-seq to identify global changes of mRNAs and lncRNAs in host cell during HCMV experimental latent infection of THP-1 cells, in an attempt to derive insights into the mechanism underlying alterations in response to infection. In this study, we profiled the expression of mRNAs and lncRNAs in host cell using the emerging RNA-seq to investigate the transcriptional changes in HCMV latent infection. ./cache/cord-298820-nogoqyxl.txt ./txt/cord-298820-nogoqyxl.txt