id author title date pages extension mime words sentences flesch summary cache txt cord-291749-revhbd0q Mongan, Arthur Elia Portable sequencer in the fight against infectious disease 2019-10-03 .txt text/plain 3735 222 40 Diagnosis can be upheld by observing the cause of disease under the microscope or detecting the presence of nucleic acid and proteins of the pathogens. Sequencing of PCR amplicons or whole pathogen genomic DNA can be applied to comprehensively screen for infecting agents and their drug resistance phenotype, if exists, at the same time. Sequencing ensures detection of DNA composition unique to an organism, the presence of antimicrobials-destroying genes, or mutation that can change the function or conformation of proteins related to drug resistance. Targeted sequencing with MinION is powerful and fast to detect pathogens in clinical samples. A novel diagnostic method for malaria using loopmediated isothermal amplification (LAMP) and MinION TM nanopore sequencer Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis MinION nanopore sequencing of multiple displacement amplified Mycobacteria DNA direct from sputum. ./cache/cord-291749-revhbd0q.txt ./txt/cord-291749-revhbd0q.txt