id author title date pages extension mime words sentences flesch summary cache txt cord-274569-jh0dyyz7 Alenquer, Marta Exosome Biogenesis, Regulation, and Function in Viral Infection 2015-09-17 .txt text/plain 7844 447 43 These routes require maturation of the EE into recycling endosomes or multivesicular bodies (MVBs), which can either fuse with lysosomes (L) to generate endolysosomes (EL) or with the plasma membrane to release intraluminal vesicles to the milieu as exosomes. These routes require maturation of the EE into recycling endosomes or multivesicular bodies (MVBs), which can either fuse with lysosomes (L) to generate endolysosomes (EL) or with the plasma membrane to release intraluminal vesicles to the milieu as exosomes. This mechanism was recently reported for HCV [113] , where exosomes derived from infected human hepatoma cells containing full-length viral RNA, along with core and envelope proteins [115] , were shown to be infectious and a major route of transmission. demonstrated that B lymphocytes infected with Epstein-Barr virus (EBV), a human gammaherpesvirus associated with a variety of lymphoblastoid and epithelial cancers, released exosomes containing MHC II molecules, and that these vesicles were capable of activating specific CD4 + T cell clones in vitro [122] . ./cache/cord-274569-jh0dyyz7.txt ./txt/cord-274569-jh0dyyz7.txt