id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-263580-zxnmylkw	Pyle, Anna Marie	RNA helicases and remodeling proteins	2011-08-20		.txt	text/plain	2650	131	50	New studies have revealed molecular mechanisms for coupling between ATP hydrolysis and unwinding, the physical basis for regulatory control by cofactors, and novel functions for RNA remodeling proteins. For DEAD-box proteins where the mechanochemical cycle has been studied, ATP hydrolysis (specifically, at the stage of Pi release) stimulates the dissociation of bound RNA molecules [46 ,47] , allowing recycling of these 'single-use' proteins [7] . Like many DEAD-box proteins, Mss116 is capable of unwinding short RNA duplexes [46 ,52,53] , however, studies of Mss116 mutants in vivo and in vitro show that its role in splicing is not necessarily dependent on helicase activity [52, 54 ] . This structure reveals the Dbp5 export motor imbedded within the complex containing other proteins involved in its function, revealing roles for small molecule activators and a conserved mechanism for ATP hydrolysis in RNA release	./cache/cord-263580-zxnmylkw.txt	./txt/cord-263580-zxnmylkw.txt