id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017732-1pwa6zsk	Miller, W. Allen	Ribosomal Frameshifting in Decoding Plant Viral RNAs	2009-07-21		.txt	text/plain	10588	477	56	As in animal viruses, the −1 ribosomal frameshift site in the viral mRNA consists of a canonical shifty heptanucleotide followed by a highly structured frameshift stimulatory element, and the gene translated as a result of frameshifting usually encodes the RNA-dependent RNA polymerase. We suggest that these experiments may not have revealed all of the sequence requirements for frameshifting on the full-length viral RNA because the frameshifting constructs tested contained a very short (10 codon) first (zero frame) ORF from the start codon through the shifty site which is followed immediately by a stop codon. The 25-kDa protein that could be generated by a frameshift followed by cleavage at the HC-Pro/P3 cleavage site is indicated (Chung et al., 2008) anticipate results of future research and structural analysis to determine how these diverse plant viral RNAs induce ribosomes to change reading frames by what may be novel mechanisms.	./cache/cord-017732-1pwa6zsk.txt	./txt/cord-017732-1pwa6zsk.txt