id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-012484-c9ajmbw2	Wahlund, Martina	The Feasibility of Host Transcriptome Profiling as a Diagnostic Tool for Microbial Etiology in Childhood Cancer Patients with Febrile Neutropenia	2020-07-26		.txt	text/plain	5085	241	45	The blood transcriptome of the children (n = 63) was investigated at time of FN diagnosed as viral, bacterial, co-infection or unknown etiology, respectively, and compared to control samples derived from 12 of the patients following the FN episode. In the present study of children during cancer treatment, the blood transcriptome was not suitable for determining the etiology of FN because of too few circulating immune cells for reliable gene expression analysis. To determine whether it is possible to detect pathogen-specific immune responses on the basis of gene expression in immunosuppressed children, we compared the blood transcriptomes of samples with viral infection, bacterial infection, co-infection, or unknown etiology with those of the control samples. To determine whether it is possible to detect pathogen-specific immune responses on the basis of gene expression in immunosuppressed children, we compared the blood transcriptomes of samples with viral infection, bacterial infection, co-infection, or unknown etiology with those of the control samples.	./cache/cord-012484-c9ajmbw2.txt	./txt/cord-012484-c9ajmbw2.txt