id author title date pages extension mime words sentences flesch summary cache txt cord-000295-ft5wl70x Tomankova, Tereza Involvement of microRNAs in physiological and pathological processes in the lung 2010-11-23 .txt text/plain 4778 318 46 These short, single-stranded RNA molecules originate from larger precursor molecules that fold to produce hairpin structures, which are subsequently processed by ribonucleases Drosha/Pasha and Dicer to form mature miRNAs. MiRNAs play role in the posttranscriptional regulation of about one third of human genes, mainly via degradation of target mRNAs. Whereas the target mRNAs are often involved in the regulation of diverse physiological processes ranging from developmental timing to apoptosis, miRNAs have a strong potential to regulate fundamental biological processes also in the lung compartment. Small non-coding RNAs (miRNAs) play pivotal role in the posttranscriptional regulation of numerous human genes, mainly via degradation of target mRNAs. There is evidence that the lung has a very specific miRNA expression profile undergoing changes during the lung development. ./cache/cord-000295-ft5wl70x.txt ./txt/cord-000295-ft5wl70x.txt