id sid tid token lemma pos cord-292559-b21j9sf3 1 1 key key JJ cord-292559-b21j9sf3 1 2 : : : cord-292559-b21j9sf3 1 3 cord-292559-b21j9sf3 cord-292559-b21j9sf3 NNP cord-292559-b21j9sf3 1 4 authors author NNS cord-292559-b21j9sf3 1 5 : : : cord-292559-b21j9sf3 1 6 Karcher Karcher NNP cord-292559-b21j9sf3 1 7 , , , cord-292559-b21j9sf3 1 8 Nicole Nicole NNP cord-292559-b21j9sf3 1 9 R. R. NNP cord-292559-b21j9sf3 1 10 ; ; : cord-292559-b21j9sf3 1 11 Barch Barch NNP cord-292559-b21j9sf3 1 12 , , , cord-292559-b21j9sf3 1 13 Deanna Deanna NNP cord-292559-b21j9sf3 1 14 M. M. NNP cord-292559-b21j9sf3 1 15 title title NN cord-292559-b21j9sf3 1 16 : : : cord-292559-b21j9sf3 2 1 The the DT cord-292559-b21j9sf3 2 2 ABCD ABCD NNP cord-292559-b21j9sf3 2 3 study study NN cord-292559-b21j9sf3 2 4 : : : cord-292559-b21j9sf3 2 5 understanding understand VBG cord-292559-b21j9sf3 2 6 the the DT cord-292559-b21j9sf3 2 7 development development NN cord-292559-b21j9sf3 2 8 of of IN cord-292559-b21j9sf3 2 9 risk risk NN cord-292559-b21j9sf3 2 10 for for IN cord-292559-b21j9sf3 2 11 mental mental JJ cord-292559-b21j9sf3 2 12 and and CC cord-292559-b21j9sf3 2 13 physical physical JJ cord-292559-b21j9sf3 2 14 health health NN cord-292559-b21j9sf3 2 15 outcomes outcome NNS cord-292559-b21j9sf3 2 16 date date NN cord-292559-b21j9sf3 2 17 : : : cord-292559-b21j9sf3 2 18 2020 2020 CD cord-292559-b21j9sf3 2 19 - - HYPH cord-292559-b21j9sf3 2 20 06 06 CD cord-292559-b21j9sf3 2 21 - - SYM cord-292559-b21j9sf3 2 22 15 15 CD cord-292559-b21j9sf3 2 23 journal journal NN cord-292559-b21j9sf3 2 24 : : : cord-292559-b21j9sf3 3 1 Neuropsychopharmacology Neuropsychopharmacology NNP cord-292559-b21j9sf3 3 2 DOI doi NN cord-292559-b21j9sf3 3 3 : : : cord-292559-b21j9sf3 4 1 10.1038 10.1038 CD cord-292559-b21j9sf3 4 2 / / SYM cord-292559-b21j9sf3 4 3 s41386 s41386 CD cord-292559-b21j9sf3 4 4 - - HYPH cord-292559-b21j9sf3 4 5 020 020 CD cord-292559-b21j9sf3 4 6 - - HYPH cord-292559-b21j9sf3 4 7 0736 0736 CD cord-292559-b21j9sf3 4 8 - - SYM cord-292559-b21j9sf3 4 9 6 6 CD cord-292559-b21j9sf3 4 10 sha sha NN cord-292559-b21j9sf3 4 11 : : : cord-292559-b21j9sf3 4 12 3fc8978a182c4f6031bb2ab3f6eae343070750de 3fc8978a182c4f6031bb2ab3f6eae343070750de CD cord-292559-b21j9sf3 4 13 doc_id doc_id CD cord-292559-b21j9sf3 4 14 : : : cord-292559-b21j9sf3 5 1 292559 292559 CD cord-292559-b21j9sf3 5 2 cord_uid cord_uid NNS cord-292559-b21j9sf3 5 3 : : : cord-292559-b21j9sf3 5 4 b21j9sf3 b21j9sf3 NNP cord-292559-b21j9sf3 5 5 Following follow VBG cord-292559-b21j9sf3 5 6 in in IN cord-292559-b21j9sf3 5 7 the the DT cord-292559-b21j9sf3 5 8 footsteps footstep NNS cord-292559-b21j9sf3 5 9 of of IN cord-292559-b21j9sf3 5 10 other other JJ cord-292559-b21j9sf3 5 11 large large JJ cord-292559-b21j9sf3 5 12 “ " `` cord-292559-b21j9sf3 5 13 population population NN cord-292559-b21j9sf3 5 14 neuroscience neuroscience NN cord-292559-b21j9sf3 5 15 ” " '' cord-292559-b21j9sf3 5 16 studies study NNS cord-292559-b21j9sf3 5 17 , , , cord-292559-b21j9sf3 5 18 the the DT cord-292559-b21j9sf3 5 19 Adolescent Adolescent NNP cord-292559-b21j9sf3 5 20 Brain Brain NNP cord-292559-b21j9sf3 5 21 Cognitive Cognitive NNP cord-292559-b21j9sf3 5 22 Development Development NNP cord-292559-b21j9sf3 5 23 ℠ ℠ NNP cord-292559-b21j9sf3 5 24 ( ( -LRB- cord-292559-b21j9sf3 5 25 ABCD ABCD NNP cord-292559-b21j9sf3 5 26 ) ) -RRB- cord-292559-b21j9sf3 5 27 study study NN cord-292559-b21j9sf3 5 28 is be VBZ cord-292559-b21j9sf3 5 29 the the DT cord-292559-b21j9sf3 5 30 largest large JJS cord-292559-b21j9sf3 5 31 in in IN cord-292559-b21j9sf3 5 32 the the DT cord-292559-b21j9sf3 5 33 U.S. U.S. NNP cord-292559-b21j9sf3 5 34 assessing assess VBG cord-292559-b21j9sf3 5 35 brain brain NN cord-292559-b21j9sf3 5 36 development development NN cord-292559-b21j9sf3 5 37 . . . cord-292559-b21j9sf3 6 1 The the DT cord-292559-b21j9sf3 6 2 study study NN cord-292559-b21j9sf3 6 3 is be VBZ cord-292559-b21j9sf3 6 4 examining examine VBG cord-292559-b21j9sf3 6 5 approximately approximately RB cord-292559-b21j9sf3 6 6 11,875 11,875 CD cord-292559-b21j9sf3 6 7 youth youth NN cord-292559-b21j9sf3 6 8 from from IN cord-292559-b21j9sf3 6 9 21 21 CD cord-292559-b21j9sf3 6 10 sites site NNS cord-292559-b21j9sf3 6 11 from from IN cord-292559-b21j9sf3 6 12 age age NN cord-292559-b21j9sf3 6 13 9 9 CD cord-292559-b21j9sf3 6 14 to to TO cord-292559-b21j9sf3 6 15 10 10 CD cord-292559-b21j9sf3 6 16 for for IN cord-292559-b21j9sf3 6 17 approximately approximately RB cord-292559-b21j9sf3 6 18 ten ten CD cord-292559-b21j9sf3 6 19 years year NNS cord-292559-b21j9sf3 6 20 into into IN cord-292559-b21j9sf3 6 21 young young JJ cord-292559-b21j9sf3 6 22 adulthood adulthood NN cord-292559-b21j9sf3 6 23 . . . cord-292559-b21j9sf3 7 1 The the DT cord-292559-b21j9sf3 7 2 ABCD ABCD NNP cord-292559-b21j9sf3 7 3 Study Study NNP cord-292559-b21j9sf3 7 4 ® ® NNP cord-292559-b21j9sf3 7 5 has have VBZ cord-292559-b21j9sf3 7 6 completed complete VBN cord-292559-b21j9sf3 7 7 recruitment recruitment NN cord-292559-b21j9sf3 7 8 for for IN cord-292559-b21j9sf3 7 9 the the DT cord-292559-b21j9sf3 7 10 baseline baseline JJ cord-292559-b21j9sf3 7 11 sample sample NN cord-292559-b21j9sf3 7 12 generally generally RB cord-292559-b21j9sf3 7 13 using use VBG cord-292559-b21j9sf3 7 14 a a DT cord-292559-b21j9sf3 7 15 multi multi JJ cord-292559-b21j9sf3 7 16 - - JJ cord-292559-b21j9sf3 7 17 stage stage JJ cord-292559-b21j9sf3 7 18 probability probability NN cord-292559-b21j9sf3 7 19 sample sample NN cord-292559-b21j9sf3 7 20 including include VBG cord-292559-b21j9sf3 7 21 a a DT cord-292559-b21j9sf3 7 22 stratified stratified JJ cord-292559-b21j9sf3 7 23 random random JJ cord-292559-b21j9sf3 7 24 sample sample NN cord-292559-b21j9sf3 7 25 of of IN cord-292559-b21j9sf3 7 26 schools school NNS cord-292559-b21j9sf3 7 27 . . . cord-292559-b21j9sf3 8 1 The the DT cord-292559-b21j9sf3 8 2 dataset dataset NN cord-292559-b21j9sf3 8 3 has have VBZ cord-292559-b21j9sf3 8 4 a a DT cord-292559-b21j9sf3 8 5 wealth wealth NN cord-292559-b21j9sf3 8 6 of of IN cord-292559-b21j9sf3 8 7 measured measure VBN cord-292559-b21j9sf3 8 8 attributes attribute NNS cord-292559-b21j9sf3 8 9 of of IN cord-292559-b21j9sf3 8 10 youths youth NNS cord-292559-b21j9sf3 8 11 and and CC cord-292559-b21j9sf3 8 12 their -PRON- PRP$ cord-292559-b21j9sf3 8 13 environment environment NN cord-292559-b21j9sf3 8 14 , , , cord-292559-b21j9sf3 8 15 including include VBG cord-292559-b21j9sf3 8 16 neuroimaging neuroimage VBG cord-292559-b21j9sf3 8 17 , , , cord-292559-b21j9sf3 8 18 cognitive cognitive NNP cord-292559-b21j9sf3 8 19 , , , cord-292559-b21j9sf3 8 20 biospecimen biospecimen NNP cord-292559-b21j9sf3 8 21 , , , cord-292559-b21j9sf3 8 22 behavioral behavioral JJ cord-292559-b21j9sf3 8 23 , , , cord-292559-b21j9sf3 8 24 youth youth NN cord-292559-b21j9sf3 8 25 self self NN cord-292559-b21j9sf3 8 26 - - HYPH cord-292559-b21j9sf3 8 27 report report NN cord-292559-b21j9sf3 8 28 and and CC cord-292559-b21j9sf3 8 29 parent parent NN cord-292559-b21j9sf3 8 30 self self NN cord-292559-b21j9sf3 8 31 - - HYPH cord-292559-b21j9sf3 8 32 report report NN cord-292559-b21j9sf3 8 33 metrics metric NNS cord-292559-b21j9sf3 8 34 , , , cord-292559-b21j9sf3 8 35 and and CC cord-292559-b21j9sf3 8 36 environmental environmental JJ cord-292559-b21j9sf3 8 37 measures measure NNS cord-292559-b21j9sf3 8 38 . . . cord-292559-b21j9sf3 9 1 The the DT cord-292559-b21j9sf3 9 2 initial initial JJ cord-292559-b21j9sf3 9 3 goal goal NN cord-292559-b21j9sf3 9 4 of of IN cord-292559-b21j9sf3 9 5 the the DT cord-292559-b21j9sf3 9 6 ABCD ABCD NNP cord-292559-b21j9sf3 9 7 Study Study NNP cord-292559-b21j9sf3 9 8 was be VBD cord-292559-b21j9sf3 9 9 to to TO cord-292559-b21j9sf3 9 10 examine examine VB cord-292559-b21j9sf3 9 11 risk risk NN cord-292559-b21j9sf3 9 12 and and CC cord-292559-b21j9sf3 9 13 resiliency resiliency NN cord-292559-b21j9sf3 9 14 factors factor NNS cord-292559-b21j9sf3 9 15 associated associate VBN cord-292559-b21j9sf3 9 16 with with IN cord-292559-b21j9sf3 9 17 the the DT cord-292559-b21j9sf3 9 18 development development NN cord-292559-b21j9sf3 9 19 of of IN cord-292559-b21j9sf3 9 20 substance substance NN cord-292559-b21j9sf3 9 21 use use NN cord-292559-b21j9sf3 9 22 , , , cord-292559-b21j9sf3 9 23 but but CC cord-292559-b21j9sf3 9 24 the the DT cord-292559-b21j9sf3 9 25 project project NN cord-292559-b21j9sf3 9 26 has have VBZ cord-292559-b21j9sf3 9 27 expanded expand VBN cord-292559-b21j9sf3 9 28 far far RB cord-292559-b21j9sf3 9 29 beyond beyond IN cord-292559-b21j9sf3 9 30 this this DT cord-292559-b21j9sf3 9 31 initial initial JJ cord-292559-b21j9sf3 9 32 set set NN cord-292559-b21j9sf3 9 33 of of IN cord-292559-b21j9sf3 9 34 questions question NNS cord-292559-b21j9sf3 9 35 and and CC cord-292559-b21j9sf3 9 36 will will MD cord-292559-b21j9sf3 9 37 also also RB cord-292559-b21j9sf3 9 38 greatly greatly RB cord-292559-b21j9sf3 9 39 inform inform VB cord-292559-b21j9sf3 9 40 our -PRON- PRP$ cord-292559-b21j9sf3 9 41 understanding understanding NN cord-292559-b21j9sf3 9 42 of of IN cord-292559-b21j9sf3 9 43 the the DT cord-292559-b21j9sf3 9 44 contributions contribution NNS cord-292559-b21j9sf3 9 45 of of IN cord-292559-b21j9sf3 9 46 biospecimens biospecimen NNS cord-292559-b21j9sf3 9 47 ( ( -LRB- cord-292559-b21j9sf3 9 48 e.g. e.g. RB cord-292559-b21j9sf3 9 49 , , , cord-292559-b21j9sf3 9 50 pubertal pubertal JJ cord-292559-b21j9sf3 9 51 hormones hormone NNS cord-292559-b21j9sf3 9 52 ) ) -RRB- cord-292559-b21j9sf3 9 53 , , , cord-292559-b21j9sf3 9 54 neural neural JJ cord-292559-b21j9sf3 9 55 alterations alteration NNS cord-292559-b21j9sf3 9 56 , , , cord-292559-b21j9sf3 9 57 and and CC cord-292559-b21j9sf3 9 58 environmental environmental JJ cord-292559-b21j9sf3 9 59 factors factor NNS cord-292559-b21j9sf3 9 60 to to IN cord-292559-b21j9sf3 9 61 the the DT cord-292559-b21j9sf3 9 62 development development NN cord-292559-b21j9sf3 9 63 of of IN cord-292559-b21j9sf3 9 64 both both DT cord-292559-b21j9sf3 9 65 healthy healthy JJ cord-292559-b21j9sf3 9 66 behavior behavior NN cord-292559-b21j9sf3 9 67 and and CC cord-292559-b21j9sf3 9 68 brain brain NN cord-292559-b21j9sf3 9 69 function function NN cord-292559-b21j9sf3 9 70 as as RB cord-292559-b21j9sf3 9 71 well well RB cord-292559-b21j9sf3 9 72 as as IN cord-292559-b21j9sf3 9 73 risk risk NN cord-292559-b21j9sf3 9 74 for for IN cord-292559-b21j9sf3 9 75 poor poor JJ cord-292559-b21j9sf3 9 76 mental mental JJ cord-292559-b21j9sf3 9 77 and and CC cord-292559-b21j9sf3 9 78 physical physical JJ cord-292559-b21j9sf3 9 79 outcomes outcome NNS cord-292559-b21j9sf3 9 80 . . . cord-292559-b21j9sf3 10 1 This this DT cord-292559-b21j9sf3 10 2 review review NN cord-292559-b21j9sf3 10 3 outlines outline VBZ cord-292559-b21j9sf3 10 4 how how WRB cord-292559-b21j9sf3 10 5 the the DT cord-292559-b21j9sf3 10 6 ABCD ABCD NNP cord-292559-b21j9sf3 10 7 Study Study NNP cord-292559-b21j9sf3 10 8 was be VBD cord-292559-b21j9sf3 10 9 designed design VBN cord-292559-b21j9sf3 10 10 to to TO cord-292559-b21j9sf3 10 11 elucidate elucidate VB cord-292559-b21j9sf3 10 12 factors factor NNS cord-292559-b21j9sf3 10 13 associated associate VBN cord-292559-b21j9sf3 10 14 with with IN cord-292559-b21j9sf3 10 15 the the DT cord-292559-b21j9sf3 10 16 development development NN cord-292559-b21j9sf3 10 17 of of IN cord-292559-b21j9sf3 10 18 negative negative JJ cord-292559-b21j9sf3 10 19 mental mental JJ cord-292559-b21j9sf3 10 20 and and CC cord-292559-b21j9sf3 10 21 physical physical JJ cord-292559-b21j9sf3 10 22 health health NN cord-292559-b21j9sf3 10 23 outcomes outcome NNS cord-292559-b21j9sf3 10 24 and and CC cord-292559-b21j9sf3 10 25 will will MD cord-292559-b21j9sf3 10 26 provide provide VB cord-292559-b21j9sf3 10 27 a a DT cord-292559-b21j9sf3 10 28 selective selective JJ cord-292559-b21j9sf3 10 29 overview overview NN cord-292559-b21j9sf3 10 30 of of IN cord-292559-b21j9sf3 10 31 results result NNS cord-292559-b21j9sf3 10 32 emerging emerge VBG cord-292559-b21j9sf3 10 33 from from IN cord-292559-b21j9sf3 10 34 the the DT cord-292559-b21j9sf3 10 35 ABCD ABCD NNP cord-292559-b21j9sf3 10 36 Study Study NNP cord-292559-b21j9sf3 10 37 . . . cord-292559-b21j9sf3 11 1 Such such JJ cord-292559-b21j9sf3 11 2 emerging emerge VBG cord-292559-b21j9sf3 11 3 data data NN cord-292559-b21j9sf3 11 4 includes include VBZ cord-292559-b21j9sf3 11 5 initial initial JJ cord-292559-b21j9sf3 11 6 validation validation NN cord-292559-b21j9sf3 11 7 of of IN cord-292559-b21j9sf3 11 8 new new JJ cord-292559-b21j9sf3 11 9 instruments instrument NNS cord-292559-b21j9sf3 11 10 , , , cord-292559-b21j9sf3 11 11 important important JJ cord-292559-b21j9sf3 11 12 new new JJ cord-292559-b21j9sf3 11 13 information information NN cord-292559-b21j9sf3 11 14 about about IN cord-292559-b21j9sf3 11 15 the the DT cord-292559-b21j9sf3 11 16 prevalence prevalence NN cord-292559-b21j9sf3 11 17 and and CC cord-292559-b21j9sf3 11 18 correlates correlate NNS cord-292559-b21j9sf3 11 19 of of IN cord-292559-b21j9sf3 11 20 mental mental JJ cord-292559-b21j9sf3 11 21 health health NN cord-292559-b21j9sf3 11 22 challenges challenge NNS cord-292559-b21j9sf3 11 23 in in IN cord-292559-b21j9sf3 11 24 middle middle JJ cord-292559-b21j9sf3 11 25 childhood childhood NN cord-292559-b21j9sf3 11 26 , , , cord-292559-b21j9sf3 11 27 and and CC cord-292559-b21j9sf3 11 28 promising promising JJ cord-292559-b21j9sf3 11 29 data datum NNS cord-292559-b21j9sf3 11 30 regarding regard VBG cord-292559-b21j9sf3 11 31 neural neural JJ cord-292559-b21j9sf3 11 32 correlates correlate NNS cord-292559-b21j9sf3 11 33 of of IN cord-292559-b21j9sf3 11 34 both both DT cord-292559-b21j9sf3 11 35 healthy healthy JJ cord-292559-b21j9sf3 11 36 and and CC cord-292559-b21j9sf3 11 37 disordered disordered JJ cord-292559-b21j9sf3 11 38 behavior behavior NN cord-292559-b21j9sf3 11 39 . . . cord-292559-b21j9sf3 12 1 In in IN cord-292559-b21j9sf3 12 2 addition addition NN cord-292559-b21j9sf3 12 3 , , , cord-292559-b21j9sf3 12 4 we -PRON- PRP cord-292559-b21j9sf3 12 5 will will MD cord-292559-b21j9sf3 12 6 discuss discuss VB cord-292559-b21j9sf3 12 7 the the DT cord-292559-b21j9sf3 12 8 challenges challenge NNS cord-292559-b21j9sf3 12 9 and and CC cord-292559-b21j9sf3 12 10 opportunities opportunity NNS cord-292559-b21j9sf3 12 11 to to IN cord-292559-b21j9sf3 12 12 understanding understand VBG cord-292559-b21j9sf3 12 13 both both DT cord-292559-b21j9sf3 12 14 healthy healthy JJ cord-292559-b21j9sf3 12 15 development development NN cord-292559-b21j9sf3 12 16 and and CC cord-292559-b21j9sf3 12 17 the the DT cord-292559-b21j9sf3 12 18 emergence emergence NN cord-292559-b21j9sf3 12 19 of of IN cord-292559-b21j9sf3 12 20 risk risk NN cord-292559-b21j9sf3 12 21 from from IN cord-292559-b21j9sf3 12 22 ABCD ABCD NNP cord-292559-b21j9sf3 12 23 Study Study NNP cord-292559-b21j9sf3 12 24 data datum NNS cord-292559-b21j9sf3 12 25 . . . cord-292559-b21j9sf3 13 1 Finally finally RB cord-292559-b21j9sf3 13 2 , , , cord-292559-b21j9sf3 13 3 we -PRON- PRP cord-292559-b21j9sf3 13 4 will will MD cord-292559-b21j9sf3 13 5 overview overview VB cord-292559-b21j9sf3 13 6 the the DT cord-292559-b21j9sf3 13 7 future future JJ cord-292559-b21j9sf3 13 8 directions direction NNS cord-292559-b21j9sf3 13 9 of of IN cord-292559-b21j9sf3 13 10 this this DT cord-292559-b21j9sf3 13 11 large large JJ cord-292559-b21j9sf3 13 12 undertaking undertaking NN cord-292559-b21j9sf3 13 13 and and CC cord-292559-b21j9sf3 13 14 the the DT cord-292559-b21j9sf3 13 15 ways way NNS cord-292559-b21j9sf3 13 16 in in IN cord-292559-b21j9sf3 13 17 which which WDT cord-292559-b21j9sf3 13 18 it -PRON- PRP cord-292559-b21j9sf3 13 19 will will MD cord-292559-b21j9sf3 13 20 shape shape VB cord-292559-b21j9sf3 13 21 our -PRON- PRP$ cord-292559-b21j9sf3 13 22 understanding understanding NN cord-292559-b21j9sf3 13 23 of of IN cord-292559-b21j9sf3 13 24 the the DT cord-292559-b21j9sf3 13 25 development development NN cord-292559-b21j9sf3 13 26 of of IN cord-292559-b21j9sf3 13 27 risk risk NN cord-292559-b21j9sf3 13 28 for for IN cord-292559-b21j9sf3 13 29 poor poor JJ cord-292559-b21j9sf3 13 30 mental mental JJ cord-292559-b21j9sf3 13 31 and and CC cord-292559-b21j9sf3 13 32 physical physical JJ cord-292559-b21j9sf3 13 33 health health NN cord-292559-b21j9sf3 13 34 outcomes outcome NNS cord-292559-b21j9sf3 13 35 . . . cord-292559-b21j9sf3 14 1 A a DT cord-292559-b21j9sf3 14 2 number number NN cord-292559-b21j9sf3 14 3 of of IN cord-292559-b21j9sf3 14 4 large large JJ cord-292559-b21j9sf3 14 5 " " `` cord-292559-b21j9sf3 14 6 population population NN cord-292559-b21j9sf3 14 7 neuroscience neuroscience NN cord-292559-b21j9sf3 14 8 " " '' cord-292559-b21j9sf3 14 9 studies study NNS cord-292559-b21j9sf3 14 10 have have VBP cord-292559-b21j9sf3 14 11 been be VBN cord-292559-b21j9sf3 14 12 undertaken undertake VBN cord-292559-b21j9sf3 14 13 over over IN cord-292559-b21j9sf3 14 14 the the DT cord-292559-b21j9sf3 14 15 past past JJ cord-292559-b21j9sf3 14 16 two two CD cord-292559-b21j9sf3 14 17 decades decade NNS cord-292559-b21j9sf3 14 18 , , , cord-292559-b21j9sf3 14 19 both both CC cord-292559-b21j9sf3 14 20 in in IN cord-292559-b21j9sf3 14 21 the the DT cord-292559-b21j9sf3 14 22 U.S. U.S. NNP cord-292559-b21j9sf3 14 23 and and CC cord-292559-b21j9sf3 14 24 internationally internationally RB cord-292559-b21j9sf3 14 25 , , , cord-292559-b21j9sf3 14 26 ushering usher VBG cord-292559-b21j9sf3 14 27 in in RP cord-292559-b21j9sf3 14 28 an an DT cord-292559-b21j9sf3 14 29 exciting exciting JJ cord-292559-b21j9sf3 14 30 new new JJ cord-292559-b21j9sf3 14 31 era era NN cord-292559-b21j9sf3 14 32 in in IN cord-292559-b21j9sf3 14 33 understanding understand VBG cord-292559-b21j9sf3 14 34 the the DT cord-292559-b21j9sf3 14 35 development development NN cord-292559-b21j9sf3 14 36 of of IN cord-292559-b21j9sf3 14 37 risk risk NN cord-292559-b21j9sf3 14 38 for for IN cord-292559-b21j9sf3 14 39 negative negative JJ cord-292559-b21j9sf3 14 40 physical physical JJ cord-292559-b21j9sf3 14 41 and and CC cord-292559-b21j9sf3 14 42 mental mental JJ cord-292559-b21j9sf3 14 43 health health NN cord-292559-b21j9sf3 14 44 outcomes outcome NNS cord-292559-b21j9sf3 14 45 . . . cord-292559-b21j9sf3 15 1 For for IN cord-292559-b21j9sf3 15 2 example example NN cord-292559-b21j9sf3 15 3 , , , cord-292559-b21j9sf3 15 4 the the DT cord-292559-b21j9sf3 15 5 Adolescent Adolescent NNP cord-292559-b21j9sf3 15 6 Brain Brain NNP cord-292559-b21j9sf3 15 7 Cognitive Cognitive NNP cord-292559-b21j9sf3 15 8 Develop develop VB cord-292559-b21j9sf3 15 9 - - HYPH cord-292559-b21j9sf3 15 10 ment ment NN cord-292559-b21j9sf3 15 11 ℠ ℠ NNP cord-292559-b21j9sf3 15 12 ( ( -LRB- cord-292559-b21j9sf3 15 13 ABCD ABCD NNP cord-292559-b21j9sf3 15 14 ) ) -RRB- cord-292559-b21j9sf3 15 15 study study NN cord-292559-b21j9sf3 15 16 is be VBZ cord-292559-b21j9sf3 15 17 currently currently RB cord-292559-b21j9sf3 15 18 underway underway JJ cord-292559-b21j9sf3 15 19 and and CC cord-292559-b21j9sf3 15 20 was be VBD cord-292559-b21j9sf3 15 21 devised devise VBN cord-292559-b21j9sf3 15 22 to to TO cord-292559-b21j9sf3 15 23 better better RB cord-292559-b21j9sf3 15 24 understand understand VB cord-292559-b21j9sf3 15 25 the the DT cord-292559-b21j9sf3 15 26 development development NN cord-292559-b21j9sf3 15 27 of of IN cord-292559-b21j9sf3 15 28 both both CC cord-292559-b21j9sf3 15 29 healthy healthy JJ cord-292559-b21j9sf3 15 30 and and CC cord-292559-b21j9sf3 15 31 disrupted disrupted JJ cord-292559-b21j9sf3 15 32 brain brain NN cord-292559-b21j9sf3 15 33 and and CC cord-292559-b21j9sf3 15 34 behavioral behavioral JJ cord-292559-b21j9sf3 15 35 development development NN cord-292559-b21j9sf3 15 36 [ [ -LRB- cord-292559-b21j9sf3 15 37 1 1 CD cord-292559-b21j9sf3 15 38 ] ] -RRB- cord-292559-b21j9sf3 15 39 [ [ -LRB- cord-292559-b21j9sf3 15 40 2 2 CD cord-292559-b21j9sf3 15 41 ] ] -RRB- cord-292559-b21j9sf3 15 42 [ [ -LRB- cord-292559-b21j9sf3 15 43 3 3 CD cord-292559-b21j9sf3 15 44 ] ] -RRB- cord-292559-b21j9sf3 15 45 . . . cord-292559-b21j9sf3 16 1 The the DT cord-292559-b21j9sf3 16 2 ABCD ABCD NNP cord-292559-b21j9sf3 16 3 Study Study NNP cord-292559-b21j9sf3 16 4 ® ® NNP cord-292559-b21j9sf3 16 5 was be VBD cord-292559-b21j9sf3 16 6 begun begin VBN cord-292559-b21j9sf3 16 7 in in IN cord-292559-b21j9sf3 16 8 the the DT cord-292559-b21j9sf3 16 9 footsteps footstep NNS cord-292559-b21j9sf3 16 10 of of IN cord-292559-b21j9sf3 16 11 several several JJ cord-292559-b21j9sf3 16 12 other other JJ cord-292559-b21j9sf3 16 13 studies study NNS cord-292559-b21j9sf3 16 14 pioneering pioneer VBG cord-292559-b21j9sf3 16 15 open open JJ cord-292559-b21j9sf3 16 16 access access NN cord-292559-b21j9sf3 16 17 techniques technique NNS cord-292559-b21j9sf3 16 18 , , , cord-292559-b21j9sf3 16 19 non non JJ cord-292559-b21j9sf3 16 20 - - JJ cord-292559-b21j9sf3 16 21 convenience convenience JJ cord-292559-b21j9sf3 16 22 study study NN cord-292559-b21j9sf3 16 23 samples sample NNS cord-292559-b21j9sf3 16 24 , , , cord-292559-b21j9sf3 16 25 and and CC cord-292559-b21j9sf3 16 26 including include VBG cord-292559-b21j9sf3 16 27 longitudinal longitudinal JJ cord-292559-b21j9sf3 16 28 and and CC cord-292559-b21j9sf3 16 29 neuroimaging neuroimage VBG cord-292559-b21j9sf3 16 30 components component NNS cord-292559-b21j9sf3 16 31 ( ( -LRB- cord-292559-b21j9sf3 16 32 for for IN cord-292559-b21j9sf3 16 33 e.g. e.g. RB cord-292559-b21j9sf3 16 34 , , , cord-292559-b21j9sf3 16 35 see see VB cord-292559-b21j9sf3 16 36 ref ref NN cord-292559-b21j9sf3 16 37 . . . cord-292559-b21j9sf3 17 1 [ [ -LRB- cord-292559-b21j9sf3 17 2 4 4 CD cord-292559-b21j9sf3 17 3 ] ] -RRB- cord-292559-b21j9sf3 17 4 [ [ -LRB- cord-292559-b21j9sf3 17 5 5 5 CD cord-292559-b21j9sf3 17 6 ] ] -RRB- cord-292559-b21j9sf3 17 7 [ [ -LRB- cord-292559-b21j9sf3 17 8 6 6 CD cord-292559-b21j9sf3 17 9 ] ] -RRB- cord-292559-b21j9sf3 17 10 ) ) -RRB- cord-292559-b21j9sf3 17 11 . . . cord-292559-b21j9sf3 18 1 The the DT cord-292559-b21j9sf3 18 2 ABCD ABCD NNP cord-292559-b21j9sf3 18 3 Study Study NNP cord-292559-b21j9sf3 18 4 is be VBZ cord-292559-b21j9sf3 18 5 the the DT cord-292559-b21j9sf3 18 6 largest large JJS cord-292559-b21j9sf3 18 7 study study NN cord-292559-b21j9sf3 18 8 in in IN cord-292559-b21j9sf3 18 9 the the DT cord-292559-b21j9sf3 18 10 U.S. U.S. NNP cord-292559-b21j9sf3 18 11 to to IN cord-292559-b21j9sf3 18 12 date date NN cord-292559-b21j9sf3 18 13 assessing assess VBG cord-292559-b21j9sf3 18 14 brain brain NN cord-292559-b21j9sf3 18 15 development development NN cord-292559-b21j9sf3 18 16 , , , cord-292559-b21j9sf3 18 17 examining examine VBG cord-292559-b21j9sf3 18 18 youth youth NN cord-292559-b21j9sf3 18 19 from from IN cord-292559-b21j9sf3 18 20 age age NN cord-292559-b21j9sf3 18 21 9 9 CD cord-292559-b21j9sf3 18 22 to to TO cord-292559-b21j9sf3 18 23 10 10 CD cord-292559-b21j9sf3 18 24 for for IN cord-292559-b21j9sf3 18 25 approximately approximately RB cord-292559-b21j9sf3 18 26 ten ten CD cord-292559-b21j9sf3 18 27 years year NNS cord-292559-b21j9sf3 18 28 into into IN cord-292559-b21j9sf3 18 29 young young JJ cord-292559-b21j9sf3 18 30 adulthood adulthood NN cord-292559-b21j9sf3 18 31 . . . cord-292559-b21j9sf3 19 1 The the DT cord-292559-b21j9sf3 19 2 ABCD ABCD NNP cord-292559-b21j9sf3 19 3 Study Study NNP cord-292559-b21j9sf3 19 4 dataset dataset NN cord-292559-b21j9sf3 19 5 has have VBZ cord-292559-b21j9sf3 19 6 a a DT cord-292559-b21j9sf3 19 7 wealth wealth NN cord-292559-b21j9sf3 19 8 of of IN cord-292559-b21j9sf3 19 9 measured measure VBN cord-292559-b21j9sf3 19 10 attributes attribute NNS cord-292559-b21j9sf3 19 11 of of IN cord-292559-b21j9sf3 19 12 youths youth NNS cord-292559-b21j9sf3 19 13 and and CC cord-292559-b21j9sf3 19 14 their -PRON- PRP$ cord-292559-b21j9sf3 19 15 environment environment NN cord-292559-b21j9sf3 19 16 , , , cord-292559-b21j9sf3 19 17 which which WDT cord-292559-b21j9sf3 19 18 will will MD cord-292559-b21j9sf3 19 19 be be VB cord-292559-b21j9sf3 19 20 described describe VBN cord-292559-b21j9sf3 19 21 below below RB cord-292559-b21j9sf3 19 22 , , , cord-292559-b21j9sf3 19 23 including include VBG cord-292559-b21j9sf3 19 24 neuroimaging neuroimage VBG cord-292559-b21j9sf3 19 25 , , , cord-292559-b21j9sf3 19 26 cognitive cognitive NNP cord-292559-b21j9sf3 19 27 , , , cord-292559-b21j9sf3 19 28 biospecimen biospecimen NNP cord-292559-b21j9sf3 19 29 , , , cord-292559-b21j9sf3 19 30 behavioral behavioral JJ cord-292559-b21j9sf3 19 31 , , , cord-292559-b21j9sf3 19 32 youth youth NN cord-292559-b21j9sf3 19 33 self self NN cord-292559-b21j9sf3 19 34 report report NN cord-292559-b21j9sf3 19 35 and and CC cord-292559-b21j9sf3 19 36 parent parent NN cord-292559-b21j9sf3 19 37 self self NN cord-292559-b21j9sf3 19 38 - - HYPH cord-292559-b21j9sf3 19 39 report report NN cord-292559-b21j9sf3 19 40 metrics metric NNS cord-292559-b21j9sf3 19 41 , , , cord-292559-b21j9sf3 19 42 and and CC cord-292559-b21j9sf3 19 43 environmental environmental JJ cord-292559-b21j9sf3 19 44 measures measure NNS cord-292559-b21j9sf3 19 45 . . . cord-292559-b21j9sf3 20 1 Initial initial JJ cord-292559-b21j9sf3 20 2 driving drive VBG cord-292559-b21j9sf3 20 3 questions question NNS cord-292559-b21j9sf3 20 4 of of IN cord-292559-b21j9sf3 20 5 the the DT cord-292559-b21j9sf3 20 6 ABCD ABCD NNP cord-292559-b21j9sf3 20 7 Study Study NNP cord-292559-b21j9sf3 20 8 included include VBD cord-292559-b21j9sf3 20 9 examining examine VBG cord-292559-b21j9sf3 20 10 risk risk NN cord-292559-b21j9sf3 20 11 and and CC cord-292559-b21j9sf3 20 12 resiliency resiliency NN cord-292559-b21j9sf3 20 13 factors factor NNS cord-292559-b21j9sf3 20 14 associated associate VBN cord-292559-b21j9sf3 20 15 with with IN cord-292559-b21j9sf3 20 16 the the DT cord-292559-b21j9sf3 20 17 development development NN cord-292559-b21j9sf3 20 18 of of IN cord-292559-b21j9sf3 20 19 substance substance NN cord-292559-b21j9sf3 20 20 use use NN cord-292559-b21j9sf3 20 21 [ [ -LRB- cord-292559-b21j9sf3 20 22 3 3 CD cord-292559-b21j9sf3 20 23 , , , cord-292559-b21j9sf3 20 24 7 7 CD cord-292559-b21j9sf3 20 25 , , , cord-292559-b21j9sf3 20 26 8 8 CD cord-292559-b21j9sf3 20 27 ] ] -RRB- cord-292559-b21j9sf3 20 28 . . . cord-292559-b21j9sf3 21 1 However however RB cord-292559-b21j9sf3 21 2 , , , cord-292559-b21j9sf3 21 3 the the DT cord-292559-b21j9sf3 21 4 ABCD ABCD NNP cord-292559-b21j9sf3 21 5 Study Study NNP cord-292559-b21j9sf3 21 6 has have VBZ cord-292559-b21j9sf3 21 7 expanded expand VBN cord-292559-b21j9sf3 21 8 beyond beyond IN cord-292559-b21j9sf3 21 9 this this DT cord-292559-b21j9sf3 21 10 initial initial JJ cord-292559-b21j9sf3 21 11 set set NN cord-292559-b21j9sf3 21 12 of of IN cord-292559-b21j9sf3 21 13 questions question NNS cord-292559-b21j9sf3 21 14 and and CC cord-292559-b21j9sf3 21 15 will will MD cord-292559-b21j9sf3 21 16 also also RB cord-292559-b21j9sf3 21 17 greatly greatly RB cord-292559-b21j9sf3 21 18 inform inform VB cord-292559-b21j9sf3 21 19 our -PRON- PRP$ cord-292559-b21j9sf3 21 20 understanding understanding NN cord-292559-b21j9sf3 21 21 of of IN cord-292559-b21j9sf3 21 22 the the DT cord-292559-b21j9sf3 21 23 contributions contribution NNS cord-292559-b21j9sf3 21 24 of of IN cord-292559-b21j9sf3 21 25 biospecimen biospecimen NN cord-292559-b21j9sf3 21 26 - - HYPH cord-292559-b21j9sf3 21 27 derived derive VBN cord-292559-b21j9sf3 21 28 ( ( -LRB- cord-292559-b21j9sf3 21 29 e.g. e.g. RB cord-292559-b21j9sf3 21 30 , , , cord-292559-b21j9sf3 21 31 pubertal pubertal JJ cord-292559-b21j9sf3 21 32 hormones hormone NNS cord-292559-b21j9sf3 21 33 , , , cord-292559-b21j9sf3 21 34 genomic genomic JJ cord-292559-b21j9sf3 21 35 , , , cord-292559-b21j9sf3 21 36 and and CC cord-292559-b21j9sf3 21 37 epigenetic epigenetic JJ cord-292559-b21j9sf3 21 38 factors factor NNS cord-292559-b21j9sf3 21 39 ) ) -RRB- cord-292559-b21j9sf3 21 40 , , , cord-292559-b21j9sf3 21 41 neural neural JJ cord-292559-b21j9sf3 21 42 , , , cord-292559-b21j9sf3 21 43 and and CC cord-292559-b21j9sf3 21 44 environmental environmental JJ cord-292559-b21j9sf3 21 45 factors factor NNS cord-292559-b21j9sf3 21 46 to to IN cord-292559-b21j9sf3 21 47 the the DT cord-292559-b21j9sf3 21 48 etiology etiology NN cord-292559-b21j9sf3 21 49 of of IN cord-292559-b21j9sf3 21 50 mental mental JJ cord-292559-b21j9sf3 21 51 and and CC cord-292559-b21j9sf3 21 52 physical physical JJ cord-292559-b21j9sf3 21 53 outcomes outcome NNS cord-292559-b21j9sf3 21 54 from from IN cord-292559-b21j9sf3 21 55 middle middle JJ cord-292559-b21j9sf3 21 56 childhood childhood NN cord-292559-b21j9sf3 21 57 through through IN cord-292559-b21j9sf3 21 58 early early JJ cord-292559-b21j9sf3 21 59 adulthood adulthood NN cord-292559-b21j9sf3 21 60 [ [ -LRB- cord-292559-b21j9sf3 21 61 9 9 CD cord-292559-b21j9sf3 21 62 ] ] -RRB- cord-292559-b21j9sf3 21 63 . . . cord-292559-b21j9sf3 22 1 The the DT cord-292559-b21j9sf3 22 2 ABCD ABCD NNP cord-292559-b21j9sf3 22 3 Study Study NNP cord-292559-b21j9sf3 22 4 provides provide VBZ cord-292559-b21j9sf3 22 5 many many JJ cord-292559-b21j9sf3 22 6 unique unique JJ cord-292559-b21j9sf3 22 7 opportunities opportunity NNS cord-292559-b21j9sf3 22 8 for for IN cord-292559-b21j9sf3 22 9 understanding understand VBG cord-292559-b21j9sf3 22 10 the the DT cord-292559-b21j9sf3 22 11 development development NN cord-292559-b21j9sf3 22 12 of of IN cord-292559-b21j9sf3 22 13 both both DT cord-292559-b21j9sf3 22 14 healthy healthy JJ cord-292559-b21j9sf3 22 15 behaviors behavior NNS cord-292559-b21j9sf3 22 16 and and CC cord-292559-b21j9sf3 22 17 risk risk NN cord-292559-b21j9sf3 22 18 for for IN cord-292559-b21j9sf3 22 19 mental mental JJ cord-292559-b21j9sf3 22 20 health health NN cord-292559-b21j9sf3 22 21 challenges challenge NNS cord-292559-b21j9sf3 22 22 . . . cord-292559-b21j9sf3 23 1 First first RB cord-292559-b21j9sf3 23 2 , , , cord-292559-b21j9sf3 23 3 the the DT cord-292559-b21j9sf3 23 4 ABCD ABCD NNP cord-292559-b21j9sf3 23 5 Study Study NNP cord-292559-b21j9sf3 23 6 utilized utilize VBD cord-292559-b21j9sf3 23 7 a a DT cord-292559-b21j9sf3 23 8 school school NN cord-292559-b21j9sf3 23 9 - - HYPH cord-292559-b21j9sf3 23 10 based base VBN cord-292559-b21j9sf3 23 11 national national JJ cord-292559-b21j9sf3 23 12 recruitment recruitment NN cord-292559-b21j9sf3 23 13 strategy strategy NN cord-292559-b21j9sf3 23 14 with with IN cord-292559-b21j9sf3 23 15 limited limited JJ cord-292559-b21j9sf3 23 16 exclusion exclusion NN cord-292559-b21j9sf3 23 17 criteria criterion NNS cord-292559-b21j9sf3 23 18 , , , cord-292559-b21j9sf3 23 19 helping help VBG cord-292559-b21j9sf3 23 20 to to TO cord-292559-b21j9sf3 23 21 overcome overcome VB cord-292559-b21j9sf3 23 22 challenges challenge NNS cord-292559-b21j9sf3 23 23 to to IN cord-292559-b21j9sf3 23 24 previous previous JJ cord-292559-b21j9sf3 23 25 general general JJ cord-292559-b21j9sf3 23 26 population population NN cord-292559-b21j9sf3 23 27 studies study NNS cord-292559-b21j9sf3 23 28 that that WDT cord-292559-b21j9sf3 23 29 generally generally RB cord-292559-b21j9sf3 23 30 did do VBD cord-292559-b21j9sf3 23 31 not not RB cord-292559-b21j9sf3 23 32 include include VB cord-292559-b21j9sf3 23 33 neuroimaging neuroimage VBG cord-292559-b21j9sf3 23 34 [ [ -LRB- cord-292559-b21j9sf3 23 35 10 10 CD cord-292559-b21j9sf3 23 36 ] ] -RRB- cord-292559-b21j9sf3 23 37 as as RB cord-292559-b21j9sf3 23 38 well well RB cord-292559-b21j9sf3 23 39 as as IN cord-292559-b21j9sf3 23 40 attempts attempt NNS cord-292559-b21j9sf3 23 41 to to TO cord-292559-b21j9sf3 23 42 understand understand VB cord-292559-b21j9sf3 23 43 the the DT cord-292559-b21j9sf3 23 44 risk risk NN cord-292559-b21j9sf3 23 45 factors factor NNS cord-292559-b21j9sf3 23 46 associated associate VBN cord-292559-b21j9sf3 23 47 with with IN cord-292559-b21j9sf3 23 48 negative negative JJ cord-292559-b21j9sf3 23 49 outcomes outcome NNS cord-292559-b21j9sf3 23 50 that that WDT cord-292559-b21j9sf3 23 51 relied rely VBD cord-292559-b21j9sf3 23 52 on on IN cord-292559-b21j9sf3 23 53 convenience convenience NN cord-292559-b21j9sf3 23 54 samples sample NNS cord-292559-b21j9sf3 23 55 [ [ -LRB- cord-292559-b21j9sf3 23 56 11 11 CD cord-292559-b21j9sf3 23 57 ] ] -RRB- cord-292559-b21j9sf3 23 58 . . . cord-292559-b21j9sf3 24 1 Second second RB cord-292559-b21j9sf3 24 2 , , , cord-292559-b21j9sf3 24 3 the the DT cord-292559-b21j9sf3 24 4 ABCD ABCD NNP cord-292559-b21j9sf3 24 5 Study Study NNP cord-292559-b21j9sf3 24 6 also also RB cord-292559-b21j9sf3 24 7 includes include VBZ cord-292559-b21j9sf3 24 8 an an DT cord-292559-b21j9sf3 24 9 embedded embed VBN cord-292559-b21j9sf3 24 10 twin twin NN cord-292559-b21j9sf3 24 11 sample sample NN cord-292559-b21j9sf3 24 12 . . . cord-292559-b21j9sf3 25 1 This this DT cord-292559-b21j9sf3 25 2 will will MD cord-292559-b21j9sf3 25 3 allow allow VB cord-292559-b21j9sf3 25 4 researchers researcher NNS cord-292559-b21j9sf3 25 5 to to TO cord-292559-b21j9sf3 25 6 better better RB cord-292559-b21j9sf3 25 7 disentangle disentangle VB cord-292559-b21j9sf3 25 8 the the DT cord-292559-b21j9sf3 25 9 influences influence NNS cord-292559-b21j9sf3 25 10 of of IN cord-292559-b21j9sf3 25 11 genetic genetic JJ cord-292559-b21j9sf3 25 12 versus versus IN cord-292559-b21j9sf3 25 13 environmental environmental JJ cord-292559-b21j9sf3 25 14 factors factor NNS cord-292559-b21j9sf3 25 15 on on IN cord-292559-b21j9sf3 25 16 development development NN cord-292559-b21j9sf3 25 17 [ [ -LRB- cord-292559-b21j9sf3 25 18 12 12 CD cord-292559-b21j9sf3 25 19 ] ] -RRB- cord-292559-b21j9sf3 25 20 . . . cord-292559-b21j9sf3 26 1 Third third RB cord-292559-b21j9sf3 26 2 , , , cord-292559-b21j9sf3 26 3 the the DT cord-292559-b21j9sf3 26 4 ABCD ABCD NNP cord-292559-b21j9sf3 26 5 Study Study NNP cord-292559-b21j9sf3 26 6 has have VBZ cord-292559-b21j9sf3 26 7 an an DT cord-292559-b21j9sf3 26 8 unprecedented unprecedented JJ cord-292559-b21j9sf3 26 9 sample sample NN cord-292559-b21j9sf3 26 10 size size NN cord-292559-b21j9sf3 26 11 ( ( -LRB- cord-292559-b21j9sf3 26 12 i.e. i.e. FW cord-292559-b21j9sf3 26 13 , , , cord-292559-b21j9sf3 26 14 11,875 11,875 CD cord-292559-b21j9sf3 26 15 youth youth NN cord-292559-b21j9sf3 26 16 at at IN cord-292559-b21j9sf3 26 17 baseline baseline NN cord-292559-b21j9sf3 26 18 ) ) -RRB- cord-292559-b21j9sf3 26 19 . . . cord-292559-b21j9sf3 27 1 This this DT cord-292559-b21j9sf3 27 2 enables enable VBZ cord-292559-b21j9sf3 27 3 the the DT cord-292559-b21j9sf3 27 4 development development NN cord-292559-b21j9sf3 27 5 of of IN cord-292559-b21j9sf3 27 6 reliable reliable JJ cord-292559-b21j9sf3 27 7 standards standard NNS cord-292559-b21j9sf3 27 8 of of IN cord-292559-b21j9sf3 27 9 development development NN cord-292559-b21j9sf3 27 10 across across IN cord-292559-b21j9sf3 27 11 a a DT cord-292559-b21j9sf3 27 12 number number NN cord-292559-b21j9sf3 27 13 of of IN cord-292559-b21j9sf3 27 14 metrics metric NNS cord-292559-b21j9sf3 27 15 , , , cord-292559-b21j9sf3 27 16 including include VBG cord-292559-b21j9sf3 27 17 the the DT cord-292559-b21j9sf3 27 18 brain brain NN cord-292559-b21j9sf3 27 19 , , , cord-292559-b21j9sf3 27 20 biospecimens biospecimens NNP cord-292559-b21j9sf3 27 21 ( ( -LRB- cord-292559-b21j9sf3 27 22 e.g. e.g. RB cord-292559-b21j9sf3 27 23 , , , cord-292559-b21j9sf3 27 24 pubertal pubertal JJ cord-292559-b21j9sf3 27 25 hormones hormone NNS cord-292559-b21j9sf3 27 26 ) ) -RRB- cord-292559-b21j9sf3 27 27 , , , cord-292559-b21j9sf3 27 28 and and CC cord-292559-b21j9sf3 27 29 cognition cognition NN cord-292559-b21j9sf3 27 30 . . . cord-292559-b21j9sf3 28 1 Fourth fourth RB cord-292559-b21j9sf3 28 2 , , , cord-292559-b21j9sf3 28 3 the the DT cord-292559-b21j9sf3 28 4 ABCD ABCD NNP cord-292559-b21j9sf3 28 5 Study Study NNP cord-292559-b21j9sf3 28 6 focuses focus VBZ cord-292559-b21j9sf3 28 7 on on IN cord-292559-b21j9sf3 28 8 adolescence adolescence NN cord-292559-b21j9sf3 28 9 . . . cord-292559-b21j9sf3 29 1 Adolescence adolescence NN cord-292559-b21j9sf3 29 2 is be VBZ cord-292559-b21j9sf3 29 3 arguably arguably RB cord-292559-b21j9sf3 29 4 a a DT cord-292559-b21j9sf3 29 5 critical critical JJ cord-292559-b21j9sf3 29 6 and and CC cord-292559-b21j9sf3 29 7 unique unique JJ cord-292559-b21j9sf3 29 8 period period NN cord-292559-b21j9sf3 29 9 for for IN cord-292559-b21j9sf3 29 10 understanding understand VBG cord-292559-b21j9sf3 29 11 the the DT cord-292559-b21j9sf3 29 12 evolution evolution NN cord-292559-b21j9sf3 29 13 of of IN cord-292559-b21j9sf3 29 14 risk risk NN cord-292559-b21j9sf3 29 15 and and CC cord-292559-b21j9sf3 29 16 resiliency resiliency NN cord-292559-b21j9sf3 29 17 [ [ -LRB- cord-292559-b21j9sf3 29 18 13 13 CD cord-292559-b21j9sf3 29 19 ] ] -RRB- cord-292559-b21j9sf3 29 20 . . . cord-292559-b21j9sf3 30 1 Fifth fifth JJ cord-292559-b21j9sf3 30 2 , , , cord-292559-b21j9sf3 30 3 the the DT cord-292559-b21j9sf3 30 4 ABCD ABCD NNP cord-292559-b21j9sf3 30 5 Study Study NNP cord-292559-b21j9sf3 30 6 will will MD cord-292559-b21j9sf3 30 7 follow follow VB cord-292559-b21j9sf3 30 8 youth youth NN cord-292559-b21j9sf3 30 9 longitudinally longitudinally RB cord-292559-b21j9sf3 30 10 throughout throughout IN cord-292559-b21j9sf3 30 11 adolescence adolescence NN cord-292559-b21j9sf3 30 12 . . . cord-292559-b21j9sf3 31 1 This this DT cord-292559-b21j9sf3 31 2 will will MD cord-292559-b21j9sf3 31 3 enable enable VB cord-292559-b21j9sf3 31 4 examining examine VBG cord-292559-b21j9sf3 31 5 which which WDT cord-292559-b21j9sf3 31 6 factors factor NNS cord-292559-b21j9sf3 31 7 most most RBS cord-292559-b21j9sf3 31 8 strongly strongly RB cord-292559-b21j9sf3 31 9 predict predict VBP cord-292559-b21j9sf3 31 10 the the DT cord-292559-b21j9sf3 31 11 emergence emergence NN cord-292559-b21j9sf3 31 12 and and CC cord-292559-b21j9sf3 31 13 progression progression NN cord-292559-b21j9sf3 31 14 of of IN cord-292559-b21j9sf3 31 15 both both CC cord-292559-b21j9sf3 31 16 positive positive JJ cord-292559-b21j9sf3 31 17 and and CC cord-292559-b21j9sf3 31 18 negative negative JJ cord-292559-b21j9sf3 31 19 physical physical JJ cord-292559-b21j9sf3 31 20 and and CC cord-292559-b21j9sf3 31 21 mental mental JJ cord-292559-b21j9sf3 31 22 health health NN cord-292559-b21j9sf3 31 23 outcomes outcome NNS cord-292559-b21j9sf3 31 24 . . . cord-292559-b21j9sf3 32 1 The the DT cord-292559-b21j9sf3 32 2 current current JJ cord-292559-b21j9sf3 32 3 review review NN cord-292559-b21j9sf3 32 4 will will MD cord-292559-b21j9sf3 32 5 describe describe VB cord-292559-b21j9sf3 32 6 how how WRB cord-292559-b21j9sf3 32 7 the the DT cord-292559-b21j9sf3 32 8 ABCD ABCD NNP cord-292559-b21j9sf3 32 9 Study Study NNP cord-292559-b21j9sf3 32 10 was be VBD cord-292559-b21j9sf3 32 11 designed design VBN cord-292559-b21j9sf3 32 12 to to TO cord-292559-b21j9sf3 32 13 elucidate elucidate VB cord-292559-b21j9sf3 32 14 factors factor NNS cord-292559-b21j9sf3 32 15 associated associate VBN cord-292559-b21j9sf3 32 16 with with IN cord-292559-b21j9sf3 32 17 the the DT cord-292559-b21j9sf3 32 18 development development NN cord-292559-b21j9sf3 32 19 of of IN cord-292559-b21j9sf3 32 20 negative negative JJ cord-292559-b21j9sf3 32 21 mental mental JJ cord-292559-b21j9sf3 32 22 and and CC cord-292559-b21j9sf3 32 23 physical physical JJ cord-292559-b21j9sf3 32 24 health health NN cord-292559-b21j9sf3 32 25 outcomes outcome NNS cord-292559-b21j9sf3 32 26 . . . cord-292559-b21j9sf3 33 1 This this DT cord-292559-b21j9sf3 33 2 review review NN cord-292559-b21j9sf3 33 3 will will MD cord-292559-b21j9sf3 33 4 also also RB cord-292559-b21j9sf3 33 5 provide provide VB cord-292559-b21j9sf3 33 6 a a DT cord-292559-b21j9sf3 33 7 selective selective JJ cord-292559-b21j9sf3 33 8 overview overview NN cord-292559-b21j9sf3 33 9 of of IN cord-292559-b21j9sf3 33 10 results result NNS cord-292559-b21j9sf3 33 11 already already RB cord-292559-b21j9sf3 33 12 emerging emerge VBG cord-292559-b21j9sf3 33 13 from from IN cord-292559-b21j9sf3 33 14 the the DT cord-292559-b21j9sf3 33 15 ABCD ABCD NNP cord-292559-b21j9sf3 33 16 Study Study NNP cord-292559-b21j9sf3 33 17 . . . cord-292559-b21j9sf3 34 1 This this DT cord-292559-b21j9sf3 34 2 review review NN cord-292559-b21j9sf3 34 3 will will MD cord-292559-b21j9sf3 34 4 discuss discuss VB cord-292559-b21j9sf3 34 5 the the DT cord-292559-b21j9sf3 34 6 challenges challenge NNS cord-292559-b21j9sf3 34 7 and and CC cord-292559-b21j9sf3 34 8 opportunities opportunity NNS cord-292559-b21j9sf3 34 9 to to IN cord-292559-b21j9sf3 34 10 understanding understand VBG cord-292559-b21j9sf3 34 11 the the DT cord-292559-b21j9sf3 34 12 development development NN cord-292559-b21j9sf3 34 13 of of IN cord-292559-b21j9sf3 34 14 risk risk NN cord-292559-b21j9sf3 34 15 using use VBG cord-292559-b21j9sf3 34 16 the the DT cord-292559-b21j9sf3 34 17 ABCD ABCD NNP cord-292559-b21j9sf3 34 18 Study Study NNP cord-292559-b21j9sf3 34 19 . . . cord-292559-b21j9sf3 35 1 Lastly lastly RB cord-292559-b21j9sf3 35 2 , , , cord-292559-b21j9sf3 35 3 we -PRON- PRP cord-292559-b21j9sf3 35 4 will will MD cord-292559-b21j9sf3 35 5 discuss discuss VB cord-292559-b21j9sf3 35 6 the the DT cord-292559-b21j9sf3 35 7 future future JJ cord-292559-b21j9sf3 35 8 directions direction NNS cord-292559-b21j9sf3 35 9 of of IN cord-292559-b21j9sf3 35 10 this this DT cord-292559-b21j9sf3 35 11 massive massive JJ cord-292559-b21j9sf3 35 12 undertaking undertaking NN cord-292559-b21j9sf3 35 13 that that WDT cord-292559-b21j9sf3 35 14 will will MD cord-292559-b21j9sf3 35 15 shape shape VB cord-292559-b21j9sf3 35 16 our -PRON- PRP$ cord-292559-b21j9sf3 35 17 understanding understanding NN cord-292559-b21j9sf3 35 18 of of IN cord-292559-b21j9sf3 35 19 the the DT cord-292559-b21j9sf3 35 20 development development NN cord-292559-b21j9sf3 35 21 of of IN cord-292559-b21j9sf3 35 22 risk risk NN cord-292559-b21j9sf3 35 23 in in IN cord-292559-b21j9sf3 35 24 adolescence adolescence NN cord-292559-b21j9sf3 35 25 . . . cord-292559-b21j9sf3 36 1 The the DT cord-292559-b21j9sf3 36 2 ABCD ABCD NNP cord-292559-b21j9sf3 36 3 Study Study NNP cord-292559-b21j9sf3 36 4 has have VBZ cord-292559-b21j9sf3 36 5 completed complete VBN cord-292559-b21j9sf3 36 6 recruitment recruitment NN cord-292559-b21j9sf3 36 7 for for IN cord-292559-b21j9sf3 36 8 the the DT cord-292559-b21j9sf3 36 9 baseline baseline JJ cord-292559-b21j9sf3 36 10 study study NN cord-292559-b21j9sf3 36 11 sample sample NN cord-292559-b21j9sf3 36 12 ( ( -LRB- cord-292559-b21j9sf3 36 13 N n NN cord-292559-b21j9sf3 36 14 = = SYM cord-292559-b21j9sf3 36 15 11,875 11,875 CD cord-292559-b21j9sf3 36 16 ; ; : cord-292559-b21j9sf3 36 17 youth youth NN cord-292559-b21j9sf3 36 18 = = SYM cord-292559-b21j9sf3 36 19 9 9 CD cord-292559-b21j9sf3 36 20 - - HYPH cord-292559-b21j9sf3 36 21 10-years 10-years CD cord-292559-b21j9sf3 36 22 - - HYPH cord-292559-b21j9sf3 36 23 old old JJ cord-292559-b21j9sf3 36 24 ; ; : cord-292559-b21j9sf3 36 25 47.8 47.8 CD cord-292559-b21j9sf3 36 26 % % NN cord-292559-b21j9sf3 36 27 female female NN cord-292559-b21j9sf3 36 28 ; ; : cord-292559-b21j9sf3 36 29 52.1 52.1 CD cord-292559-b21j9sf3 36 30 % % NN cord-292559-b21j9sf3 36 31 White White NNP cord-292559-b21j9sf3 36 32 , , , cord-292559-b21j9sf3 36 33 15 15 CD cord-292559-b21j9sf3 36 34 .0 .0 CD cord-292559-b21j9sf3 36 35 % % NN cord-292559-b21j9sf3 36 36 Black Black NNP cord-292559-b21j9sf3 36 37 , , , cord-292559-b21j9sf3 36 38 20.3 20.3 CD cord-292559-b21j9sf3 36 39 % % NN cord-292559-b21j9sf3 36 40 Hispanic hispanic JJ cord-292559-b21j9sf3 36 41 , , , cord-292559-b21j9sf3 36 42 2.1 2.1 CD cord-292559-b21j9sf3 36 43 % % NN cord-292559-b21j9sf3 36 44 Asian Asian NNP cord-292559-b21j9sf3 36 45 , , , cord-292559-b21j9sf3 36 46 and and CC cord-292559-b21j9sf3 36 47 10.5 10.5 CD cord-292559-b21j9sf3 36 48 % % NN cord-292559-b21j9sf3 36 49 other other JJ cord-292559-b21j9sf3 36 50 [ [ -LRB- cord-292559-b21j9sf3 36 51 e.g. e.g. RB cord-292559-b21j9sf3 36 52 , , , cord-292559-b21j9sf3 36 53 biracial biracial JJ cord-292559-b21j9sf3 36 54 ] ] -RRB- cord-292559-b21j9sf3 36 55 ) ) -RRB- cord-292559-b21j9sf3 36 56 and and CC cord-292559-b21j9sf3 36 57 will will MD cord-292559-b21j9sf3 36 58 be be VB cord-292559-b21j9sf3 36 59 continuing continue VBG cord-292559-b21j9sf3 36 60 to to TO cord-292559-b21j9sf3 36 61 follow follow VB cord-292559-b21j9sf3 36 62 these these DT cord-292559-b21j9sf3 36 63 youth youth NN cord-292559-b21j9sf3 36 64 for for IN cord-292559-b21j9sf3 36 65 at at RB cord-292559-b21j9sf3 36 66 least least RBS cord-292559-b21j9sf3 36 67 ten ten CD cord-292559-b21j9sf3 36 68 years year NNS cord-292559-b21j9sf3 36 69 . . . cord-292559-b21j9sf3 37 1 An an DT cord-292559-b21j9sf3 37 2 important important JJ cord-292559-b21j9sf3 37 3 motivation motivation NN cord-292559-b21j9sf3 37 4 for for IN cord-292559-b21j9sf3 37 5 ABCD ABCD NNP cord-292559-b21j9sf3 37 6 Study Study NNP cord-292559-b21j9sf3 37 7 sampling sampling NN cord-292559-b21j9sf3 37 8 techniques technique NNS cord-292559-b21j9sf3 37 9 was be VBD cord-292559-b21j9sf3 37 10 to to TO cord-292559-b21j9sf3 37 11 reflect reflect VB cord-292559-b21j9sf3 37 12 the the DT cord-292559-b21j9sf3 37 13 sociodemographic sociodemographic JJ cord-292559-b21j9sf3 37 14 variation variation NN cord-292559-b21j9sf3 37 15 of of IN cord-292559-b21j9sf3 37 16 the the DT cord-292559-b21j9sf3 37 17 US US NNP cord-292559-b21j9sf3 37 18 population population NN cord-292559-b21j9sf3 37 19 . . . cord-292559-b21j9sf3 38 1 The the DT cord-292559-b21j9sf3 38 2 recruitment recruitment NN cord-292559-b21j9sf3 38 3 approach approach NN cord-292559-b21j9sf3 38 4 of of IN cord-292559-b21j9sf3 38 5 the the DT cord-292559-b21j9sf3 38 6 ABCD ABCD NNP cord-292559-b21j9sf3 38 7 Study Study NNP cord-292559-b21j9sf3 38 8 was be VBD cord-292559-b21j9sf3 38 9 generally generally RB cord-292559-b21j9sf3 38 10 through through IN cord-292559-b21j9sf3 38 11 public public JJ cord-292559-b21j9sf3 38 12 schools school NNS cord-292559-b21j9sf3 38 13 , , , cord-292559-b21j9sf3 38 14 including include VBG cord-292559-b21j9sf3 38 15 charter charter NN cord-292559-b21j9sf3 38 16 and and CC cord-292559-b21j9sf3 38 17 private private JJ cord-292559-b21j9sf3 38 18 elementary elementary JJ cord-292559-b21j9sf3 38 19 schools school NNS cord-292559-b21j9sf3 38 20 , , , cord-292559-b21j9sf3 38 21 though though IN cord-292559-b21j9sf3 38 22 the the DT cord-292559-b21j9sf3 38 23 embedded embed VBN cord-292559-b21j9sf3 38 24 twin twin NN cord-292559-b21j9sf3 38 25 sample sample NN cord-292559-b21j9sf3 38 26 ( ( -LRB- cord-292559-b21j9sf3 38 27 described describe VBN cord-292559-b21j9sf3 38 28 below below RB cord-292559-b21j9sf3 38 29 ) ) -RRB- cord-292559-b21j9sf3 38 30 used use VBD cord-292559-b21j9sf3 38 31 a a DT cord-292559-b21j9sf3 38 32 birth birth NN cord-292559-b21j9sf3 38 33 record record NN cord-292559-b21j9sf3 38 34 approach approach NN cord-292559-b21j9sf3 38 35 . . . cord-292559-b21j9sf3 39 1 Overall overall RB cord-292559-b21j9sf3 39 2 , , , cord-292559-b21j9sf3 39 3 the the DT cord-292559-b21j9sf3 39 4 ABCD ABCD NNP cord-292559-b21j9sf3 39 5 Study Study NNP cord-292559-b21j9sf3 39 6 aimed aim VBD cord-292559-b21j9sf3 39 7 to to TO cord-292559-b21j9sf3 39 8 utilize utilize VB cord-292559-b21j9sf3 39 9 a a DT cord-292559-b21j9sf3 39 10 multi multi JJ cord-292559-b21j9sf3 39 11 - - JJ cord-292559-b21j9sf3 39 12 stage stage JJ cord-292559-b21j9sf3 39 13 probability probability NN cord-292559-b21j9sf3 39 14 sample sample NN cord-292559-b21j9sf3 39 15 of of IN cord-292559-b21j9sf3 39 16 eligible eligible JJ cord-292559-b21j9sf3 39 17 youth youth NN cord-292559-b21j9sf3 39 18 , , , cord-292559-b21j9sf3 39 19 selecting select VBG cord-292559-b21j9sf3 39 20 a a DT cord-292559-b21j9sf3 39 21 stratified stratified JJ cord-292559-b21j9sf3 39 22 , , , cord-292559-b21j9sf3 39 23 probability probability NN cord-292559-b21j9sf3 39 24 sample sample NN cord-292559-b21j9sf3 39 25 of of IN cord-292559-b21j9sf3 39 26 schools school NNS cord-292559-b21j9sf3 39 27 across across IN cord-292559-b21j9sf3 39 28 the the DT cord-292559-b21j9sf3 39 29 U.S. U.S. NNP cord-292559-b21j9sf3 39 30 in in IN cord-292559-b21j9sf3 39 31 order order NN cord-292559-b21j9sf3 39 32 to to TO cord-292559-b21j9sf3 39 33 capture capture VB cord-292559-b21j9sf3 39 34 demographic demographic JJ cord-292559-b21j9sf3 39 35 diversity diversity NN cord-292559-b21j9sf3 39 36 [ [ -LRB- cord-292559-b21j9sf3 39 37 14 14 CD cord-292559-b21j9sf3 39 38 ] ] -RRB- cord-292559-b21j9sf3 39 39 . . . cord-292559-b21j9sf3 40 1 However however RB cord-292559-b21j9sf3 40 2 , , , cord-292559-b21j9sf3 40 3 some some DT cord-292559-b21j9sf3 40 4 participants participant NNS cord-292559-b21j9sf3 40 5 ( ( -LRB- cord-292559-b21j9sf3 40 6 < < NNP cord-292559-b21j9sf3 40 7 10 10 CD cord-292559-b21j9sf3 40 8 % % NN cord-292559-b21j9sf3 40 9 ) ) -RRB- cord-292559-b21j9sf3 40 10 were be VBD cord-292559-b21j9sf3 40 11 recruited recruit VBN cord-292559-b21j9sf3 40 12 via via IN cord-292559-b21j9sf3 40 13 other other JJ cord-292559-b21j9sf3 40 14 means mean NNS cord-292559-b21j9sf3 40 15 , , , cord-292559-b21j9sf3 40 16 including include VBG cord-292559-b21j9sf3 40 17 through through IN cord-292559-b21j9sf3 40 18 community community NN cord-292559-b21j9sf3 40 19 events event NNS cord-292559-b21j9sf3 40 20 , , , cord-292559-b21j9sf3 40 21 non non JJ cord-292559-b21j9sf3 40 22 - - JJ cord-292559-b21j9sf3 40 23 targeted targeted JJ cord-292559-b21j9sf3 40 24 schools school NNS cord-292559-b21j9sf3 40 25 , , , cord-292559-b21j9sf3 40 26 and and CC cord-292559-b21j9sf3 40 27 referral referral NN cord-292559-b21j9sf3 40 28 systems system NNS cord-292559-b21j9sf3 40 29 . . . cord-292559-b21j9sf3 41 1 Further further RB cord-292559-b21j9sf3 41 2 , , , cord-292559-b21j9sf3 41 3 the the DT cord-292559-b21j9sf3 41 4 selection selection NN cord-292559-b21j9sf3 41 5 of of IN cord-292559-b21j9sf3 41 6 collaborating collaborate VBG cord-292559-b21j9sf3 41 7 sites site NNS cord-292559-b21j9sf3 41 8 was be VBD cord-292559-b21j9sf3 41 9 constrained constrain VBN cord-292559-b21j9sf3 41 10 by by IN cord-292559-b21j9sf3 41 11 the the DT cord-292559-b21j9sf3 41 12 requirement requirement NN cord-292559-b21j9sf3 41 13 that that WDT cord-292559-b21j9sf3 41 14 engaged engage VBD cord-292559-b21j9sf3 41 15 locations location NNS cord-292559-b21j9sf3 41 16 had have VBD cord-292559-b21j9sf3 41 17 to to TO cord-292559-b21j9sf3 41 18 have have VB cord-292559-b21j9sf3 41 19 both both CC cord-292559-b21j9sf3 41 20 the the DT cord-292559-b21j9sf3 41 21 research research NN cord-292559-b21j9sf3 41 22 expertize expertize NN cord-292559-b21j9sf3 41 23 and and CC cord-292559-b21j9sf3 41 24 the the DT cord-292559-b21j9sf3 41 25 neuroimaging neuroimaging NN cord-292559-b21j9sf3 41 26 equipment equipment NN cord-292559-b21j9sf3 41 27 required require VBN cord-292559-b21j9sf3 41 28 by by IN cord-292559-b21j9sf3 41 29 ABCD ABCD NNP cord-292559-b21j9sf3 41 30 Study Study NNP cord-292559-b21j9sf3 41 31 protocol protocol NN cord-292559-b21j9sf3 41 32 [ [ -LRB- cord-292559-b21j9sf3 41 33 14 14 CD cord-292559-b21j9sf3 41 34 ] ] -RRB- cord-292559-b21j9sf3 41 35 . . . cord-292559-b21j9sf3 42 1 The the DT cord-292559-b21j9sf3 42 2 ABCD ABCD NNP cord-292559-b21j9sf3 42 3 Study Study NNP cord-292559-b21j9sf3 42 4 has have VBZ cord-292559-b21j9sf3 42 5 21 21 CD cord-292559-b21j9sf3 42 6 sites site NNS cord-292559-b21j9sf3 42 7 that that WDT cord-292559-b21j9sf3 42 8 are be VBP cord-292559-b21j9sf3 42 9 distributed distribute VBN cord-292559-b21j9sf3 42 10 nationally nationally RB cord-292559-b21j9sf3 42 11 . . . cord-292559-b21j9sf3 43 1 For for IN cord-292559-b21j9sf3 43 2 each each DT cord-292559-b21j9sf3 43 3 site site NN cord-292559-b21j9sf3 43 4 , , , cord-292559-b21j9sf3 43 5 the the DT cord-292559-b21j9sf3 43 6 ABCD ABCD NNP cord-292559-b21j9sf3 43 7 Study Study NNP cord-292559-b21j9sf3 43 8 created create VBD cord-292559-b21j9sf3 43 9 a a DT cord-292559-b21j9sf3 43 10 catchment catchment NN cord-292559-b21j9sf3 43 11 area area NN cord-292559-b21j9sf3 43 12 , , , cord-292559-b21j9sf3 43 13 defined define VBN cord-292559-b21j9sf3 43 14 as as IN cord-292559-b21j9sf3 43 15 all all DT cord-292559-b21j9sf3 43 16 schools school NNS cord-292559-b21j9sf3 43 17 within within IN cord-292559-b21j9sf3 43 18 50 50 CD cord-292559-b21j9sf3 43 19 miles mile NNS cord-292559-b21j9sf3 43 20 of of IN cord-292559-b21j9sf3 43 21 the the DT cord-292559-b21j9sf3 43 22 research research NN cord-292559-b21j9sf3 43 23 institution institution NN cord-292559-b21j9sf3 43 24 [ [ -LRB- cord-292559-b21j9sf3 43 25 14 14 CD cord-292559-b21j9sf3 43 26 ] ] -RRB- cord-292559-b21j9sf3 43 27 . . . cord-292559-b21j9sf3 44 1 Each each DT cord-292559-b21j9sf3 44 2 school school NN cord-292559-b21j9sf3 44 3 within within IN cord-292559-b21j9sf3 44 4 the the DT cord-292559-b21j9sf3 44 5 catchment catchment NN cord-292559-b21j9sf3 44 6 area area NN cord-292559-b21j9sf3 44 7 was be VBD cord-292559-b21j9sf3 44 8 coded code VBN cord-292559-b21j9sf3 44 9 according accord VBG cord-292559-b21j9sf3 44 10 to to IN cord-292559-b21j9sf3 44 11 several several JJ cord-292559-b21j9sf3 44 12 factors factor NNS cord-292559-b21j9sf3 44 13 , , , cord-292559-b21j9sf3 44 14 including include VBG cord-292559-b21j9sf3 44 15 geographical geographical JJ cord-292559-b21j9sf3 44 16 location location NN cord-292559-b21j9sf3 44 17 , , , cord-292559-b21j9sf3 44 18 racial racial JJ cord-292559-b21j9sf3 44 19 , , , cord-292559-b21j9sf3 44 20 ethnic ethnic JJ cord-292559-b21j9sf3 44 21 and and CC cord-292559-b21j9sf3 44 22 sex sex NN cord-292559-b21j9sf3 44 23 composition composition NN cord-292559-b21j9sf3 44 24 , , , cord-292559-b21j9sf3 44 25 and and CC cord-292559-b21j9sf3 44 26 percentage percentage NN cord-292559-b21j9sf3 44 27 of of IN cord-292559-b21j9sf3 44 28 students student NNS cord-292559-b21j9sf3 44 29 receiving receive VBG cord-292559-b21j9sf3 44 30 free free JJ cord-292559-b21j9sf3 44 31 or or CC cord-292559-b21j9sf3 44 32 subsidized subsidized JJ cord-292559-b21j9sf3 44 33 lunches lunch NNS cord-292559-b21j9sf3 44 34 as as IN cord-292559-b21j9sf3 44 35 an an DT cord-292559-b21j9sf3 44 36 index index NN cord-292559-b21j9sf3 44 37 of of IN cord-292559-b21j9sf3 44 38 socioeconomic socioeconomic JJ cord-292559-b21j9sf3 44 39 status status NN cord-292559-b21j9sf3 44 40 ( ( -LRB- cord-292559-b21j9sf3 44 41 SES SES NNP cord-292559-b21j9sf3 44 42 ) ) -RRB- cord-292559-b21j9sf3 44 43 . . . cord-292559-b21j9sf3 45 1 Based base VBN cord-292559-b21j9sf3 45 2 on on IN cord-292559-b21j9sf3 45 3 this this DT cord-292559-b21j9sf3 45 4 information information NN cord-292559-b21j9sf3 45 5 , , , cord-292559-b21j9sf3 45 6 the the DT cord-292559-b21j9sf3 45 7 ABCD ABCD NNP cord-292559-b21j9sf3 45 8 Study Study NNP cord-292559-b21j9sf3 45 9 used use VBD cord-292559-b21j9sf3 45 10 stratified stratified JJ cord-292559-b21j9sf3 45 11 sampling sampling NN cord-292559-b21j9sf3 45 12 of of IN cord-292559-b21j9sf3 45 13 schools school NNS cord-292559-b21j9sf3 45 14 within within IN cord-292559-b21j9sf3 45 15 each each DT cord-292559-b21j9sf3 45 16 site site NN cord-292559-b21j9sf3 45 17 's 's POS cord-292559-b21j9sf3 45 18 catchment catchment NN cord-292559-b21j9sf3 45 19 area area NN cord-292559-b21j9sf3 45 20 , , , cord-292559-b21j9sf3 45 21 and and CC cord-292559-b21j9sf3 45 22 a a DT cord-292559-b21j9sf3 45 23 subset subset NN cord-292559-b21j9sf3 45 24 of of IN cord-292559-b21j9sf3 45 25 schools school NNS cord-292559-b21j9sf3 45 26 was be VBD cord-292559-b21j9sf3 45 27 randomly randomly RB cord-292559-b21j9sf3 45 28 selected select VBN cord-292559-b21j9sf3 45 29 from from IN cord-292559-b21j9sf3 45 30 this this DT cord-292559-b21j9sf3 45 31 list list NN cord-292559-b21j9sf3 45 32 of of IN cord-292559-b21j9sf3 45 33 potential potential JJ cord-292559-b21j9sf3 45 34 schools school NNS cord-292559-b21j9sf3 45 35 within within IN cord-292559-b21j9sf3 45 36 each each DT cord-292559-b21j9sf3 45 37 catchment catchment NN cord-292559-b21j9sf3 45 38 area area NN cord-292559-b21j9sf3 45 39 . . . cord-292559-b21j9sf3 46 1 Procedures procedure NNS cord-292559-b21j9sf3 46 2 were be VBD cord-292559-b21j9sf3 46 3 used use VBN cord-292559-b21j9sf3 46 4 to to TO cord-292559-b21j9sf3 46 5 ensure ensure VB cord-292559-b21j9sf3 46 6 that that IN cord-292559-b21j9sf3 46 7 systematic systematic JJ cord-292559-b21j9sf3 46 8 sampling sampling NN cord-292559-b21j9sf3 46 9 biases bias NNS cord-292559-b21j9sf3 46 10 in in IN cord-292559-b21j9sf3 46 11 recruitment recruitment NN cord-292559-b21j9sf3 46 12 at at IN cord-292559-b21j9sf3 46 13 the the DT cord-292559-b21j9sf3 46 14 school school NN cord-292559-b21j9sf3 46 15 level level NN cord-292559-b21j9sf3 46 16 were be VBD cord-292559-b21j9sf3 46 17 minimized minimize VBN cord-292559-b21j9sf3 46 18 [ [ -LRB- cord-292559-b21j9sf3 46 19 14 14 CD cord-292559-b21j9sf3 46 20 ] ] -RRB- cord-292559-b21j9sf3 46 21 . . . cord-292559-b21j9sf3 47 1 The the DT cord-292559-b21j9sf3 47 2 ABCD ABCD NNP cord-292559-b21j9sf3 47 3 Study Study NNP cord-292559-b21j9sf3 47 4 then then RB cord-292559-b21j9sf3 47 5 recruited recruit VBD cord-292559-b21j9sf3 47 6 eligible eligible JJ cord-292559-b21j9sf3 47 7 children child NNS cord-292559-b21j9sf3 47 8 from from IN cord-292559-b21j9sf3 47 9 each each DT cord-292559-b21j9sf3 47 10 of of IN cord-292559-b21j9sf3 47 11 the the DT cord-292559-b21j9sf3 47 12 randomly randomly RB cord-292559-b21j9sf3 47 13 selected select VBN cord-292559-b21j9sf3 47 14 schools school NNS cord-292559-b21j9sf3 47 15 within within IN cord-292559-b21j9sf3 47 16 the the DT cord-292559-b21j9sf3 47 17 catchment catchment NN cord-292559-b21j9sf3 47 18 area area NN cord-292559-b21j9sf3 47 19 . . . cord-292559-b21j9sf3 48 1 Initial initial JJ cord-292559-b21j9sf3 48 2 recruitment recruitment NN cord-292559-b21j9sf3 48 3 often often RB cord-292559-b21j9sf3 48 4 involved involve VBD cord-292559-b21j9sf3 48 5 the the DT cord-292559-b21j9sf3 48 6 delivery delivery NN cord-292559-b21j9sf3 48 7 of of IN cord-292559-b21j9sf3 48 8 hard hard JJ cord-292559-b21j9sf3 48 9 and and CC cord-292559-b21j9sf3 48 10 electronic electronic JJ cord-292559-b21j9sf3 48 11 copies copy NNS cord-292559-b21j9sf3 48 12 of of IN cord-292559-b21j9sf3 48 13 recruitment recruitment NN cord-292559-b21j9sf3 48 14 materials material NNS cord-292559-b21j9sf3 48 15 to to IN cord-292559-b21j9sf3 48 16 caregivers caregiver NNS cord-292559-b21j9sf3 48 17 . . . cord-292559-b21j9sf3 49 1 In in IN cord-292559-b21j9sf3 49 2 total total JJ cord-292559-b21j9sf3 49 3 , , , cord-292559-b21j9sf3 49 4 11,875 11,875 CD cord-292559-b21j9sf3 49 5 children child NNS cord-292559-b21j9sf3 49 6 completed complete VBD cord-292559-b21j9sf3 49 7 the the DT cord-292559-b21j9sf3 49 8 baseline baseline JJ cord-292559-b21j9sf3 49 9 assessment assessment NN cord-292559-b21j9sf3 49 10 . . . cord-292559-b21j9sf3 50 1 In in IN cord-292559-b21j9sf3 50 2 the the DT cord-292559-b21j9sf3 50 3 end end NN cord-292559-b21j9sf3 50 4 , , , cord-292559-b21j9sf3 50 5 the the DT cord-292559-b21j9sf3 50 6 ABCD ABCD NNP cord-292559-b21j9sf3 50 7 Study Study NNP cord-292559-b21j9sf3 50 8 sample sample NN cord-292559-b21j9sf3 50 9 is be VBZ cord-292559-b21j9sf3 50 10 epidemiologically epidemiologically RB cord-292559-b21j9sf3 50 11 informed informed JJ cord-292559-b21j9sf3 50 12 and and CC cord-292559-b21j9sf3 50 13 designed design VBN cord-292559-b21j9sf3 50 14 to to TO cord-292559-b21j9sf3 50 15 reduce reduce VB cord-292559-b21j9sf3 50 16 selection selection NN cord-292559-b21j9sf3 50 17 bias bias NN cord-292559-b21j9sf3 50 18 that that WDT cord-292559-b21j9sf3 50 19 plagues plague VBZ cord-292559-b21j9sf3 50 20 convenience convenience NN cord-292559-b21j9sf3 50 21 samples sample NNS cord-292559-b21j9sf3 50 22 . . . cord-292559-b21j9sf3 51 1 However however RB cord-292559-b21j9sf3 51 2 , , , cord-292559-b21j9sf3 51 3 the the DT cord-292559-b21j9sf3 51 4 degree degree NN cord-292559-b21j9sf3 51 5 to to TO cord-292559-b21j9sf3 51 6 which which WDT cord-292559-b21j9sf3 51 7 this this DT cord-292559-b21j9sf3 51 8 sample sample NN cord-292559-b21j9sf3 51 9 is be VBZ cord-292559-b21j9sf3 51 10 fully fully RB cord-292559-b21j9sf3 51 11 representative representative JJ cord-292559-b21j9sf3 51 12 of of IN cord-292559-b21j9sf3 51 13 the the DT cord-292559-b21j9sf3 51 14 U.S. U.S. NNP cord-292559-b21j9sf3 51 15 population population NN cord-292559-b21j9sf3 51 16 will will MD cord-292559-b21j9sf3 51 17 vary vary VB cord-292559-b21j9sf3 51 18 across across IN cord-292559-b21j9sf3 51 19 outcome outcome NN cord-292559-b21j9sf3 51 20 measure measure NN cord-292559-b21j9sf3 51 21 examined examine VBN cord-292559-b21j9sf3 51 22 . . . cord-292559-b21j9sf3 52 1 The the DT cord-292559-b21j9sf3 52 2 use use NN cord-292559-b21j9sf3 52 3 of of IN cord-292559-b21j9sf3 52 4 weighting weighting NN cord-292559-b21j9sf3 52 5 methods method NNS cord-292559-b21j9sf3 52 6 that that WDT cord-292559-b21j9sf3 52 7 evaluate evaluate VBP cord-292559-b21j9sf3 52 8 the the DT cord-292559-b21j9sf3 52 9 distributions distribution NNS cord-292559-b21j9sf3 52 10 in in IN cord-292559-b21j9sf3 52 11 relationship relationship NN cord-292559-b21j9sf3 52 12 to to IN cord-292559-b21j9sf3 52 13 U.S. U.S. NNP cord-292559-b21j9sf3 52 14 demographic demographic JJ cord-292559-b21j9sf3 52 15 characteristics characteristic NNS cord-292559-b21j9sf3 52 16 will will MD cord-292559-b21j9sf3 52 17 be be VB cord-292559-b21j9sf3 52 18 a a DT cord-292559-b21j9sf3 52 19 helpful helpful JJ cord-292559-b21j9sf3 52 20 additional additional JJ cord-292559-b21j9sf3 52 21 tool tool NN cord-292559-b21j9sf3 52 22 when when WRB cord-292559-b21j9sf3 52 23 attempting attempt VBG cord-292559-b21j9sf3 52 24 to to TO cord-292559-b21j9sf3 52 25 make make VB cord-292559-b21j9sf3 52 26 claims claim NNS cord-292559-b21j9sf3 52 27 about about IN cord-292559-b21j9sf3 52 28 representativeness representativeness NN cord-292559-b21j9sf3 52 29 [ [ -LRB- cord-292559-b21j9sf3 52 30 15 15 CD cord-292559-b21j9sf3 52 31 ] ] -RRB- cord-292559-b21j9sf3 52 32 . . . cord-292559-b21j9sf3 53 1 In in IN cord-292559-b21j9sf3 53 2 addition addition NN cord-292559-b21j9sf3 53 3 to to IN cord-292559-b21j9sf3 53 4 this this DT cord-292559-b21j9sf3 53 5 school school NN cord-292559-b21j9sf3 53 6 - - HYPH cord-292559-b21j9sf3 53 7 based base VBN cord-292559-b21j9sf3 53 8 approach approach NN cord-292559-b21j9sf3 53 9 , , , cord-292559-b21j9sf3 53 10 there there EX cord-292559-b21j9sf3 53 11 are be VBP cord-292559-b21j9sf3 53 12 four four CD cord-292559-b21j9sf3 53 13 ABCD ABCD NNP cord-292559-b21j9sf3 53 14 Study Study NNP cord-292559-b21j9sf3 53 15 sites site NNS cord-292559-b21j9sf3 53 16 that that WDT cord-292559-b21j9sf3 53 17 recruited recruit VBD cord-292559-b21j9sf3 53 18 samples sample NNS cord-292559-b21j9sf3 53 19 of of IN cord-292559-b21j9sf3 53 20 monozygotic monozygotic NNS cord-292559-b21j9sf3 53 21 and and CC cord-292559-b21j9sf3 53 22 dizygotic dizygotic JJ cord-292559-b21j9sf3 53 23 twins twin NNS cord-292559-b21j9sf3 53 24 ( ( -LRB- cord-292559-b21j9sf3 53 25 Washington Washington NNP cord-292559-b21j9sf3 53 26 University University NNP cord-292559-b21j9sf3 53 27 in in IN cord-292559-b21j9sf3 53 28 St. St. NNP cord-292559-b21j9sf3 53 29 Louis Louis NNP cord-292559-b21j9sf3 53 30 , , , cord-292559-b21j9sf3 53 31 University University NNP cord-292559-b21j9sf3 53 32 of of IN cord-292559-b21j9sf3 53 33 Minnesota Minnesota NNP cord-292559-b21j9sf3 53 34 , , , cord-292559-b21j9sf3 53 35 University University NNP cord-292559-b21j9sf3 53 36 of of IN cord-292559-b21j9sf3 53 37 Colorado Colorado NNP cord-292559-b21j9sf3 53 38 at at IN cord-292559-b21j9sf3 53 39 Boulder Boulder NNP cord-292559-b21j9sf3 53 40 , , , cord-292559-b21j9sf3 53 41 and and CC cord-292559-b21j9sf3 53 42 Virginia Virginia NNP cord-292559-b21j9sf3 53 43 Commonwealth Commonwealth NNP cord-292559-b21j9sf3 53 44 University University NNP cord-292559-b21j9sf3 53 45 ) ) -RRB- cord-292559-b21j9sf3 53 46 , , , cord-292559-b21j9sf3 53 47 resulting result VBG cord-292559-b21j9sf3 53 48 in~860 in~860 JJ cord-292559-b21j9sf3 53 49 twin twin JJ cord-292559-b21j9sf3 53 50 pairs pair NNS cord-292559-b21j9sf3 53 51 in in IN cord-292559-b21j9sf3 53 52 the the DT cord-292559-b21j9sf3 53 53 baseline baseline JJ cord-292559-b21j9sf3 53 54 sample sample NN cord-292559-b21j9sf3 53 55 . . . cord-292559-b21j9sf3 54 1 These these DT cord-292559-b21j9sf3 54 2 sites site NNS cord-292559-b21j9sf3 54 3 each each DT cord-292559-b21j9sf3 54 4 have have VBP cord-292559-b21j9sf3 54 5 over over IN cord-292559-b21j9sf3 54 6 25 25 CD cord-292559-b21j9sf3 54 7 years year NNS cord-292559-b21j9sf3 54 8 of of IN cord-292559-b21j9sf3 54 9 experiences experience NNS cord-292559-b21j9sf3 54 10 in in IN cord-292559-b21j9sf3 54 11 the the DT cord-292559-b21j9sf3 54 12 recruitment recruitment NN cord-292559-b21j9sf3 54 13 of of IN cord-292559-b21j9sf3 54 14 twin twin JJ cord-292559-b21j9sf3 54 15 populations population NNS cord-292559-b21j9sf3 54 16 and and CC cord-292559-b21j9sf3 54 17 therefore therefore RB cord-292559-b21j9sf3 54 18 used use VBD cord-292559-b21j9sf3 54 19 existing existing JJ cord-292559-b21j9sf3 54 20 recruitment recruitment NN cord-292559-b21j9sf3 54 21 processes process NNS cord-292559-b21j9sf3 54 22 [ [ -LRB- cord-292559-b21j9sf3 54 23 12 12 CD cord-292559-b21j9sf3 54 24 ] ] -RRB- cord-292559-b21j9sf3 54 25 . . . cord-292559-b21j9sf3 55 1 For for IN cord-292559-b21j9sf3 55 2 example example NN cord-292559-b21j9sf3 55 3 , , , cord-292559-b21j9sf3 55 4 these these DT cord-292559-b21j9sf3 55 5 sites site NNS cord-292559-b21j9sf3 55 6 used use VBD cord-292559-b21j9sf3 55 7 approved approve VBD cord-292559-b21j9sf3 55 8 vital vital JJ cord-292559-b21j9sf3 55 9 records record NNS cord-292559-b21j9sf3 55 10 approaches approach NNS cord-292559-b21j9sf3 55 11 to to TO cord-292559-b21j9sf3 55 12 capture capture VB cord-292559-b21j9sf3 55 13 a a DT cord-292559-b21j9sf3 55 14 diverse diverse JJ cord-292559-b21j9sf3 55 15 set set NN cord-292559-b21j9sf3 55 16 of of IN cord-292559-b21j9sf3 55 17 twins twin NNS cord-292559-b21j9sf3 55 18 generally generally RB cord-292559-b21j9sf3 55 19 representative representative JJ cord-292559-b21j9sf3 55 20 of of IN cord-292559-b21j9sf3 55 21 the the DT cord-292559-b21j9sf3 55 22 demographics demographic NNS cord-292559-b21j9sf3 55 23 of of IN cord-292559-b21j9sf3 55 24 their -PRON- PRP$ cord-292559-b21j9sf3 55 25 respective respective JJ cord-292559-b21j9sf3 55 26 states state NNS cord-292559-b21j9sf3 55 27 [ [ -LRB- cord-292559-b21j9sf3 55 28 12 12 CD cord-292559-b21j9sf3 55 29 ] ] -RRB- cord-292559-b21j9sf3 55 30 . . . cord-292559-b21j9sf3 56 1 Each each DT cord-292559-b21j9sf3 56 2 of of IN cord-292559-b21j9sf3 56 3 these these DT cord-292559-b21j9sf3 56 4 sites site NNS cord-292559-b21j9sf3 56 5 also also RB cord-292559-b21j9sf3 56 6 recruited recruit VBD cord-292559-b21j9sf3 56 7 " " `` cord-292559-b21j9sf3 56 8 singletons singleton NNS cord-292559-b21j9sf3 56 9 " " '' cord-292559-b21j9sf3 56 10 using use VBG cord-292559-b21j9sf3 56 11 the the DT cord-292559-b21j9sf3 56 12 school school NN cord-292559-b21j9sf3 56 13 - - HYPH cord-292559-b21j9sf3 56 14 based base VBN cord-292559-b21j9sf3 56 15 approach approach NN cord-292559-b21j9sf3 56 16 described describe VBN cord-292559-b21j9sf3 56 17 above above RB cord-292559-b21j9sf3 56 18 . . . cord-292559-b21j9sf3 57 1 The the DT cord-292559-b21j9sf3 57 2 inclusion inclusion NN cord-292559-b21j9sf3 57 3 of of IN cord-292559-b21j9sf3 57 4 twin twin JJ cord-292559-b21j9sf3 57 5 samples sample NNS cord-292559-b21j9sf3 57 6 was be VBD cord-292559-b21j9sf3 57 7 designed design VBN cord-292559-b21j9sf3 57 8 to to TO cord-292559-b21j9sf3 57 9 enhance enhance VB cord-292559-b21j9sf3 57 10 the the DT cord-292559-b21j9sf3 57 11 ability ability NN cord-292559-b21j9sf3 57 12 to to TO cord-292559-b21j9sf3 57 13 make make VB cord-292559-b21j9sf3 57 14 causal causal JJ cord-292559-b21j9sf3 57 15 inferences inference NNS cord-292559-b21j9sf3 57 16 about about IN cord-292559-b21j9sf3 57 17 factors factor NNS cord-292559-b21j9sf3 57 18 contributing contribute VBG cord-292559-b21j9sf3 57 19 to to IN cord-292559-b21j9sf3 57 20 both both CC cord-292559-b21j9sf3 57 21 healthy healthy JJ cord-292559-b21j9sf3 57 22 and and CC cord-292559-b21j9sf3 57 23 disordered disordered JJ cord-292559-b21j9sf3 57 24 brain brain NN cord-292559-b21j9sf3 57 25 and and CC cord-292559-b21j9sf3 57 26 behavioral behavioral JJ cord-292559-b21j9sf3 57 27 development development NN cord-292559-b21j9sf3 57 28 . . . cord-292559-b21j9sf3 58 1 For for IN cord-292559-b21j9sf3 58 2 more more JJR cord-292559-b21j9sf3 58 3 details detail NNS cord-292559-b21j9sf3 58 4 on on IN cord-292559-b21j9sf3 58 5 sampling sampling NN cord-292559-b21j9sf3 58 6 strategy strategy NN cord-292559-b21j9sf3 58 7 , , , cord-292559-b21j9sf3 58 8 recruitment recruitment NN cord-292559-b21j9sf3 58 9 , , , cord-292559-b21j9sf3 58 10 and and CC cord-292559-b21j9sf3 58 11 retention retention NN cord-292559-b21j9sf3 58 12 , , , cord-292559-b21j9sf3 58 13 including include VBG cord-292559-b21j9sf3 58 14 twin twin JJ cord-292559-b21j9sf3 58 15 sample sample NN cord-292559-b21j9sf3 58 16 recruitment recruitment NN cord-292559-b21j9sf3 58 17 , , , cord-292559-b21j9sf3 58 18 please please UH cord-292559-b21j9sf3 58 19 see see VB cord-292559-b21j9sf3 58 20 refs ref NNS cord-292559-b21j9sf3 58 21 . . . cord-292559-b21j9sf3 59 1 [ [ -LRB- cord-292559-b21j9sf3 59 2 12 12 CD cord-292559-b21j9sf3 59 3 , , , cord-292559-b21j9sf3 59 4 14 14 CD cord-292559-b21j9sf3 59 5 , , , cord-292559-b21j9sf3 59 6 16 16 CD cord-292559-b21j9sf3 59 7 ] ] -RRB- cord-292559-b21j9sf3 59 8 . . . cord-292559-b21j9sf3 60 1 The the DT cord-292559-b21j9sf3 60 2 ABCD ABCD NNP cord-292559-b21j9sf3 60 3 Study Study NNP cord-292559-b21j9sf3 60 4 is be VBZ cord-292559-b21j9sf3 60 5 a a DT cord-292559-b21j9sf3 60 6 consortium consortium NN cord-292559-b21j9sf3 60 7 composed compose VBN cord-292559-b21j9sf3 60 8 of of IN cord-292559-b21j9sf3 60 9 a a DT cord-292559-b21j9sf3 60 10 Coordinating Coordinating NNP cord-292559-b21j9sf3 60 11 Center Center NNP cord-292559-b21j9sf3 60 12 , , , cord-292559-b21j9sf3 60 13 a a DT cord-292559-b21j9sf3 60 14 Data Data NNP cord-292559-b21j9sf3 60 15 Analysis Analysis NNP cord-292559-b21j9sf3 60 16 , , , cord-292559-b21j9sf3 60 17 and and CC cord-292559-b21j9sf3 60 18 Informatics Informatics NNP cord-292559-b21j9sf3 60 19 Center Center NNP cord-292559-b21j9sf3 60 20 , , , cord-292559-b21j9sf3 60 21 and and CC cord-292559-b21j9sf3 60 22 members member NNS cord-292559-b21j9sf3 60 23 from from IN cord-292559-b21j9sf3 60 24 the the DT cord-292559-b21j9sf3 60 25 21 21 CD cord-292559-b21j9sf3 60 26 research research NN cord-292559-b21j9sf3 60 27 sites site NNS cord-292559-b21j9sf3 60 28 ( ( -LRB- cord-292559-b21j9sf3 60 29 https://abcdstudy.org/study-sites/ https://abcdstudy.org/study-sites/ NNP cord-292559-b21j9sf3 60 30 ) ) -RRB- cord-292559-b21j9sf3 60 31 . . . cord-292559-b21j9sf3 61 1 Work work NN cord-292559-b21j9sf3 61 2 groups group NNS cord-292559-b21j9sf3 61 3 facilitate facilitate VBP cord-292559-b21j9sf3 61 4 data datum NNS cord-292559-b21j9sf3 61 5 collection collection NN cord-292559-b21j9sf3 61 6 and and CC cord-292559-b21j9sf3 61 7 quality quality NN cord-292559-b21j9sf3 61 8 control control NN cord-292559-b21j9sf3 61 9 for for IN cord-292559-b21j9sf3 61 10 current current JJ cord-292559-b21j9sf3 61 11 and and CC cord-292559-b21j9sf3 61 12 future future JJ cord-292559-b21j9sf3 61 13 ABCD ABCD NNP cord-292559-b21j9sf3 61 14 Study Study NNP cord-292559-b21j9sf3 61 15 data datum NNS cord-292559-b21j9sf3 61 16 collection collection NN cord-292559-b21j9sf3 61 17 waves wave NNS cord-292559-b21j9sf3 61 18 . . . cord-292559-b21j9sf3 62 1 All all DT cord-292559-b21j9sf3 62 2 youth youth NN cord-292559-b21j9sf3 62 3 are be VBP cord-292559-b21j9sf3 62 4 asked ask VBN cord-292559-b21j9sf3 62 5 to to TO cord-292559-b21j9sf3 62 6 come come VB cord-292559-b21j9sf3 62 7 for for IN cord-292559-b21j9sf3 62 8 in in IN cord-292559-b21j9sf3 62 9 - - HYPH cord-292559-b21j9sf3 62 10 person person NN cord-292559-b21j9sf3 62 11 assessment assessment NN cord-292559-b21j9sf3 62 12 sessions session NNS cord-292559-b21j9sf3 62 13 once once RB cord-292559-b21j9sf3 62 14 a a DT cord-292559-b21j9sf3 62 15 year year NN cord-292559-b21j9sf3 62 16 , , , cord-292559-b21j9sf3 62 17 with with IN cord-292559-b21j9sf3 62 18 brief brief JJ cord-292559-b21j9sf3 62 19 remote remote JJ cord-292559-b21j9sf3 62 20 assessments assessment NNS cord-292559-b21j9sf3 62 21 at at IN cord-292559-b21j9sf3 62 22 6 6 CD cord-292559-b21j9sf3 62 23 months month NNS cord-292559-b21j9sf3 62 24 between between IN cord-292559-b21j9sf3 62 25 in in IN cord-292559-b21j9sf3 62 26 - - HYPH cord-292559-b21j9sf3 62 27 person person NN cord-292559-b21j9sf3 62 28 sessions session NNS cord-292559-b21j9sf3 62 29 . . . cord-292559-b21j9sf3 63 1 Self self NN cord-292559-b21j9sf3 63 2 - - HYPH cord-292559-b21j9sf3 63 3 report report NN cord-292559-b21j9sf3 63 4 , , , cord-292559-b21j9sf3 63 5 behavioral behavioral JJ cord-292559-b21j9sf3 63 6 , , , cord-292559-b21j9sf3 63 7 and and CC cord-292559-b21j9sf3 63 8 biospecimen biospecimen NN cord-292559-b21j9sf3 63 9 collections collection NNS cord-292559-b21j9sf3 63 10 occur occur VBP cord-292559-b21j9sf3 63 11 yearly yearly RB cord-292559-b21j9sf3 63 12 , , , cord-292559-b21j9sf3 63 13 while while IN cord-292559-b21j9sf3 63 14 brain brain NN cord-292559-b21j9sf3 63 15 imaging imaging NN cord-292559-b21j9sf3 63 16 occurs occur VBZ cord-292559-b21j9sf3 63 17 bi bi NN cord-292559-b21j9sf3 63 18 - - HYPH cord-292559-b21j9sf3 63 19 annually annually RB cord-292559-b21j9sf3 63 20 ( ( -LRB- cord-292559-b21j9sf3 63 21 Table table NN cord-292559-b21j9sf3 63 22 1 1 CD cord-292559-b21j9sf3 63 23 ) ) -RRB- cord-292559-b21j9sf3 63 24 . . . cord-292559-b21j9sf3 64 1 Below below RB cord-292559-b21j9sf3 64 2 , , , cord-292559-b21j9sf3 64 3 measures measure NNS cord-292559-b21j9sf3 64 4 collected collect VBN cord-292559-b21j9sf3 64 5 for for IN cord-292559-b21j9sf3 64 6 each each DT cord-292559-b21j9sf3 64 7 of of IN cord-292559-b21j9sf3 64 8 the the DT cord-292559-b21j9sf3 64 9 assessment assessment NN cord-292559-b21j9sf3 64 10 domains domain NNS cord-292559-b21j9sf3 64 11 are be VBP cord-292559-b21j9sf3 64 12 briefly briefly RB cord-292559-b21j9sf3 64 13 reviewed review VBN cord-292559-b21j9sf3 64 14 . . . cord-292559-b21j9sf3 65 1 Many many JJ cord-292559-b21j9sf3 65 2 of of IN cord-292559-b21j9sf3 65 3 these these DT cord-292559-b21j9sf3 65 4 assessments assessment NNS cord-292559-b21j9sf3 65 5 are be VBP cord-292559-b21j9sf3 65 6 described describe VBN cord-292559-b21j9sf3 65 7 in in IN cord-292559-b21j9sf3 65 8 more more JJR cord-292559-b21j9sf3 65 9 detail detail NN cord-292559-b21j9sf3 65 10 in in IN cord-292559-b21j9sf3 65 11 a a DT cord-292559-b21j9sf3 65 12 special special JJ cord-292559-b21j9sf3 65 13 issue issue NN cord-292559-b21j9sf3 65 14 of of IN cord-292559-b21j9sf3 65 15 Developmental Developmental NNP cord-292559-b21j9sf3 65 16 Cognitive Cognitive NNP cord-292559-b21j9sf3 65 17 Neuroscience Neuroscience NNP cord-292559-b21j9sf3 65 18 published publish VBN cord-292559-b21j9sf3 65 19 in in IN cord-292559-b21j9sf3 65 20 2018 2018 CD cord-292559-b21j9sf3 65 21 [ [ -LRB- cord-292559-b21j9sf3 65 22 1 1 CD cord-292559-b21j9sf3 65 23 , , , cord-292559-b21j9sf3 65 24 7 7 CD cord-292559-b21j9sf3 65 25 , , , cord-292559-b21j9sf3 65 26 17 17 CD cord-292559-b21j9sf3 65 27 , , , cord-292559-b21j9sf3 65 28 18 18 CD cord-292559-b21j9sf3 65 29 ] ] -RRB- cord-292559-b21j9sf3 65 30 . . . cord-292559-b21j9sf3 66 1 The the DT cord-292559-b21j9sf3 66 2 ABCD ABCD NNP cord-292559-b21j9sf3 66 3 Study Study NNP cord-292559-b21j9sf3 66 4 assessments assessment NNS cord-292559-b21j9sf3 66 5 can can MD cord-292559-b21j9sf3 66 6 be be VB cord-292559-b21j9sf3 66 7 loosely loosely RB cord-292559-b21j9sf3 66 8 grouped group VBN cord-292559-b21j9sf3 66 9 into into IN cord-292559-b21j9sf3 66 10 seven seven CD cord-292559-b21j9sf3 66 11 domains domain NNS cord-292559-b21j9sf3 66 12 : : : cord-292559-b21j9sf3 66 13 substance substance NN cord-292559-b21j9sf3 66 14 use use NN cord-292559-b21j9sf3 66 15 , , , cord-292559-b21j9sf3 66 16 mental mental JJ cord-292559-b21j9sf3 66 17 health health NN cord-292559-b21j9sf3 66 18 , , , cord-292559-b21j9sf3 66 19 physical physical JJ cord-292559-b21j9sf3 66 20 health health NN cord-292559-b21j9sf3 66 21 and and CC cord-292559-b21j9sf3 66 22 biospecimens biospecimens NNP cord-292559-b21j9sf3 66 23 , , , cord-292559-b21j9sf3 66 24 neurocognition neurocognition NN cord-292559-b21j9sf3 66 25 , , , cord-292559-b21j9sf3 66 26 gender gender NN cord-292559-b21j9sf3 66 27 identity identity NN cord-292559-b21j9sf3 66 28 and and CC cord-292559-b21j9sf3 66 29 sexual sexual JJ cord-292559-b21j9sf3 66 30 health health NN cord-292559-b21j9sf3 66 31 , , , cord-292559-b21j9sf3 66 32 culture culture NN cord-292559-b21j9sf3 66 33 and and CC cord-292559-b21j9sf3 66 34 environment environment NN cord-292559-b21j9sf3 66 35 , , , cord-292559-b21j9sf3 66 36 and and CC cord-292559-b21j9sf3 66 37 brain brain NN cord-292559-b21j9sf3 66 38 imaging imaging NN cord-292559-b21j9sf3 66 39 . . . cord-292559-b21j9sf3 67 1 Each each DT cord-292559-b21j9sf3 67 2 domain domain NN cord-292559-b21j9sf3 67 3 was be VBD cord-292559-b21j9sf3 67 4 designed design VBN cord-292559-b21j9sf3 67 5 to to TO cord-292559-b21j9sf3 67 6 use use VB cord-292559-b21j9sf3 67 7 instruments instrument NNS cord-292559-b21j9sf3 67 8 with with IN cord-292559-b21j9sf3 67 9 documented documented JJ cord-292559-b21j9sf3 67 10 reliability reliability NN cord-292559-b21j9sf3 67 11 and and CC cord-292559-b21j9sf3 67 12 validity validity NN cord-292559-b21j9sf3 67 13 , , , cord-292559-b21j9sf3 67 14 be be VB cord-292559-b21j9sf3 67 15 developmentally developmentally RB cord-292559-b21j9sf3 67 16 sensitive sensitive JJ cord-292559-b21j9sf3 67 17 , , , cord-292559-b21j9sf3 67 18 engage engage VB cord-292559-b21j9sf3 67 19 the the DT cord-292559-b21j9sf3 67 20 most most RBS cord-292559-b21j9sf3 67 21 appropriate appropriate JJ cord-292559-b21j9sf3 67 22 informant informant NN cord-292559-b21j9sf3 67 23 depending depend VBG cord-292559-b21j9sf3 67 24 on on IN cord-292559-b21j9sf3 67 25 the the DT cord-292559-b21j9sf3 67 26 developmental developmental JJ cord-292559-b21j9sf3 67 27 stage stage NN cord-292559-b21j9sf3 67 28 and and CC cord-292559-b21j9sf3 67 29 domain domain NN cord-292559-b21j9sf3 67 30 ( ( -LRB- cord-292559-b21j9sf3 67 31 e.g. e.g. RB cord-292559-b21j9sf3 67 32 , , , cord-292559-b21j9sf3 67 33 parent parent NN cord-292559-b21j9sf3 67 34 versus versus IN cord-292559-b21j9sf3 67 35 youth youth NN cord-292559-b21j9sf3 67 36 ) ) -RRB- cord-292559-b21j9sf3 67 37 , , , cord-292559-b21j9sf3 67 38 minimize minimize VB cord-292559-b21j9sf3 67 39 participant participant NN cord-292559-b21j9sf3 67 40 burden burden NN cord-292559-b21j9sf3 67 41 , , , cord-292559-b21j9sf3 67 42 and and CC cord-292559-b21j9sf3 67 43 be be VB cord-292559-b21j9sf3 67 44 informed inform VBN cord-292559-b21j9sf3 67 45 by by IN cord-292559-b21j9sf3 67 46 previous previous JJ cord-292559-b21j9sf3 67 47 relevant relevant JJ cord-292559-b21j9sf3 67 48 literature literature NN cord-292559-b21j9sf3 67 49 on on IN cord-292559-b21j9sf3 67 50 both both CC cord-292559-b21j9sf3 67 51 healthy healthy JJ cord-292559-b21j9sf3 67 52 and and CC cord-292559-b21j9sf3 67 53 disordered disordered JJ cord-292559-b21j9sf3 67 54 brain brain NN cord-292559-b21j9sf3 67 55 and and CC cord-292559-b21j9sf3 67 56 behavioral behavioral JJ cord-292559-b21j9sf3 67 57 development development NN cord-292559-b21j9sf3 67 58 . . . cord-292559-b21j9sf3 68 1 Furthermore furthermore RB cord-292559-b21j9sf3 68 2 , , , cord-292559-b21j9sf3 68 3 the the DT cord-292559-b21j9sf3 68 4 inclusion inclusion NN cord-292559-b21j9sf3 68 5 of of IN cord-292559-b21j9sf3 68 6 multiple multiple JJ cord-292559-b21j9sf3 68 7 informants informant NNS cord-292559-b21j9sf3 68 8 for for IN cord-292559-b21j9sf3 68 9 certain certain JJ cord-292559-b21j9sf3 68 10 measures measure NNS cord-292559-b21j9sf3 68 11 , , , cord-292559-b21j9sf3 68 12 including include VBG cord-292559-b21j9sf3 68 13 obtaining obtain VBG cord-292559-b21j9sf3 68 14 information information NN cord-292559-b21j9sf3 68 15 from from IN cord-292559-b21j9sf3 68 16 youth youth NN cord-292559-b21j9sf3 68 17 , , , cord-292559-b21j9sf3 68 18 caregivers caregiver NNS cord-292559-b21j9sf3 68 19 , , , cord-292559-b21j9sf3 68 20 and and CC cord-292559-b21j9sf3 68 21 teachers teacher NNS cord-292559-b21j9sf3 68 22 regarding regard VBG cord-292559-b21j9sf3 68 23 youth youth NN cord-292559-b21j9sf3 68 24 mental mental JJ cord-292559-b21j9sf3 68 25 health health NN cord-292559-b21j9sf3 68 26 at at IN cord-292559-b21j9sf3 68 27 baseline baseline JJ cord-292559-b21j9sf3 68 28 ( ( -LRB- cord-292559-b21j9sf3 68 29 youth youth NN cord-292559-b21j9sf3 68 30 = = SYM cord-292559-b21j9sf3 68 31 9 9 CD cord-292559-b21j9sf3 68 32 - - HYPH cord-292559-b21j9sf3 68 33 10-years 10-years CD cord-292559-b21j9sf3 68 34 - - HYPH cord-292559-b21j9sf3 68 35 old old JJ cord-292559-b21j9sf3 68 36 ) ) -RRB- cord-292559-b21j9sf3 68 37 , , , cord-292559-b21j9sf3 68 38 helps help VBZ cord-292559-b21j9sf3 68 39 to to TO cord-292559-b21j9sf3 68 40 mitigate mitigate VB cord-292559-b21j9sf3 68 41 potential potential JJ cord-292559-b21j9sf3 68 42 unreliability unreliability NN cord-292559-b21j9sf3 68 43 of of IN cord-292559-b21j9sf3 68 44 youth youth NN cord-292559-b21j9sf3 68 45 reports report NNS cord-292559-b21j9sf3 68 46 due due JJ cord-292559-b21j9sf3 68 47 to to IN cord-292559-b21j9sf3 68 48 variability variability NN cord-292559-b21j9sf3 68 49 in in IN cord-292559-b21j9sf3 68 50 language language NN cord-292559-b21j9sf3 68 51 skills skill NNS cord-292559-b21j9sf3 68 52 and and CC cord-292559-b21j9sf3 68 53 retrospective retrospective JJ cord-292559-b21j9sf3 68 54 reporting reporting NN cord-292559-b21j9sf3 68 55 problems problem NNS cord-292559-b21j9sf3 68 56 . . . cord-292559-b21j9sf3 69 1 For for IN cord-292559-b21j9sf3 69 2 each each DT cord-292559-b21j9sf3 69 3 domain domain NN cord-292559-b21j9sf3 69 4 , , , cord-292559-b21j9sf3 69 5 additional additional JJ cord-292559-b21j9sf3 69 6 assessments assessment NNS cord-292559-b21j9sf3 69 7 have have VBP cord-292559-b21j9sf3 69 8 been be VBN cord-292559-b21j9sf3 69 9 added add VBN cord-292559-b21j9sf3 69 10 in in IN cord-292559-b21j9sf3 69 11 follow follow NN cord-292559-b21j9sf3 69 12 - - HYPH cord-292559-b21j9sf3 69 13 up up NN cord-292559-b21j9sf3 69 14 years year NNS cord-292559-b21j9sf3 69 15 , , , cord-292559-b21j9sf3 69 16 which which WDT cord-292559-b21j9sf3 69 17 are be VBP cord-292559-b21j9sf3 69 18 described describe VBN cord-292559-b21j9sf3 69 19 in in IN cord-292559-b21j9sf3 69 20 the the DT cord-292559-b21j9sf3 69 21 Annual Annual NNP cord-292559-b21j9sf3 69 22 Release Release NNP cord-292559-b21j9sf3 69 23 Notes Notes NNPS cord-292559-b21j9sf3 69 24 of of IN cord-292559-b21j9sf3 69 25 the the DT cord-292559-b21j9sf3 69 26 ABCD ABCD NNP cord-292559-b21j9sf3 69 27 Study Study NNP cord-292559-b21j9sf3 69 28 data data NN cord-292559-b21j9sf3 69 29 releases release NNS cord-292559-b21j9sf3 69 30 on on IN cord-292559-b21j9sf3 69 31 the the DT cord-292559-b21j9sf3 69 32 NIH NIH NNP cord-292559-b21j9sf3 69 33 National National NNP cord-292559-b21j9sf3 69 34 Data Data NNP cord-292559-b21j9sf3 69 35 Archive Archive NNP cord-292559-b21j9sf3 69 36 . . . cord-292559-b21j9sf3 70 1 Additionally additionally RB cord-292559-b21j9sf3 70 2 , , , cord-292559-b21j9sf3 70 3 ABCD ABCD NNP cord-292559-b21j9sf3 70 4 consortium consortium NN cord-292559-b21j9sf3 70 5 members member NNS cord-292559-b21j9sf3 70 6 have have VBP cord-292559-b21j9sf3 70 7 added add VBN cord-292559-b21j9sf3 70 8 several several JJ cord-292559-b21j9sf3 70 9 sub sub NN cord-292559-b21j9sf3 70 10 - - NNS cord-292559-b21j9sf3 70 11 studies study NNS cord-292559-b21j9sf3 70 12 to to IN cord-292559-b21j9sf3 70 13 the the DT cord-292559-b21j9sf3 70 14 ABCD ABCD NNP cord-292559-b21j9sf3 70 15 Study Study NNP cord-292559-b21j9sf3 70 16 protocol protocol NN cord-292559-b21j9sf3 70 17 for for IN cord-292559-b21j9sf3 70 18 future future JJ cord-292559-b21j9sf3 70 19 waves wave NNS cord-292559-b21j9sf3 70 20 of of IN cord-292559-b21j9sf3 70 21 data datum NNS cord-292559-b21j9sf3 70 22 collection collection NN cord-292559-b21j9sf3 70 23 . . . cord-292559-b21j9sf3 71 1 These these DT cord-292559-b21j9sf3 71 2 sub sub NN cord-292559-b21j9sf3 71 3 - - NNS cord-292559-b21j9sf3 71 4 studies study NNS cord-292559-b21j9sf3 71 5 include include VBP cord-292559-b21j9sf3 71 6 adding add VBG cord-292559-b21j9sf3 71 7 measures measure NNS cord-292559-b21j9sf3 71 8 to to TO cord-292559-b21j9sf3 71 9 address address VB cord-292559-b21j9sf3 71 10 reactions reaction NNS cord-292559-b21j9sf3 71 11 to to IN cord-292559-b21j9sf3 71 12 Hurricane Hurricane NNP cord-292559-b21j9sf3 71 13 Irma Irma NNP cord-292559-b21j9sf3 71 14 and and CC cord-292559-b21j9sf3 71 15 the the DT cord-292559-b21j9sf3 71 16 COVID-19 COVID-19 NNP cord-292559-b21j9sf3 71 17 pandemic pandemic NN cord-292559-b21j9sf3 71 18 , , , cord-292559-b21j9sf3 71 19 and and CC cord-292559-b21j9sf3 71 20 a a DT cord-292559-b21j9sf3 71 21 sub sub JJ cord-292559-b21j9sf3 71 22 - - JJ cord-292559-b21j9sf3 71 23 study study NN cord-292559-b21j9sf3 71 24 focused focus VBN cord-292559-b21j9sf3 71 25 on on IN cord-292559-b21j9sf3 71 26 behavior behavior NN cord-292559-b21j9sf3 71 27 in in IN cord-292559-b21j9sf3 71 28 youth youth NN cord-292559-b21j9sf3 71 29 that that WDT cord-292559-b21j9sf3 71 30 might may MD cord-292559-b21j9sf3 71 31 put put VB cord-292559-b21j9sf3 71 32 them -PRON- PRP cord-292559-b21j9sf3 71 33 at at IN cord-292559-b21j9sf3 71 34 risk risk NN cord-292559-b21j9sf3 71 35 for for IN cord-292559-b21j9sf3 71 36 involvement involvement NN cord-292559-b21j9sf3 71 37 in in IN cord-292559-b21j9sf3 71 38 the the DT cord-292559-b21j9sf3 71 39 justice justice NN cord-292559-b21j9sf3 71 40 system system NN cord-292559-b21j9sf3 71 41 . . . cord-292559-b21j9sf3 72 1 Substance substance NN cord-292559-b21j9sf3 72 2 use use NN cord-292559-b21j9sf3 72 3 . . . cord-292559-b21j9sf3 73 1 For for IN cord-292559-b21j9sf3 73 2 an an DT cord-292559-b21j9sf3 73 3 overview overview NN cord-292559-b21j9sf3 73 4 of of IN cord-292559-b21j9sf3 73 5 measures measure NNS cord-292559-b21j9sf3 73 6 started start VBN cord-292559-b21j9sf3 73 7 at at IN cord-292559-b21j9sf3 73 8 baseline baseline NN cord-292559-b21j9sf3 73 9 and and CC cord-292559-b21j9sf3 73 10 year year NN cord-292559-b21j9sf3 73 11 1 1 CD cord-292559-b21j9sf3 73 12 ( ( -LRB- cord-292559-b21j9sf3 73 13 youth youth NN cord-292559-b21j9sf3 73 14 = = SYM cord-292559-b21j9sf3 73 15 10 10 CD cord-292559-b21j9sf3 73 16 - - HYPH cord-292559-b21j9sf3 73 17 11-years 11-years CD cord-292559-b21j9sf3 73 18 - - HYPH cord-292559-b21j9sf3 73 19 old old JJ cord-292559-b21j9sf3 73 20 ) ) -RRB- cord-292559-b21j9sf3 73 21 , , , cord-292559-b21j9sf3 73 22 please please UH cord-292559-b21j9sf3 73 23 see see VB cord-292559-b21j9sf3 73 24 ref ref NN cord-292559-b21j9sf3 73 25 . . . cord-292559-b21j9sf3 74 1 [ [ -LRB- cord-292559-b21j9sf3 74 2 7 7 CD cord-292559-b21j9sf3 74 3 ] ] -RRB- cord-292559-b21j9sf3 74 4 . . . cord-292559-b21j9sf3 75 1 The the DT cord-292559-b21j9sf3 75 2 goal goal NN cord-292559-b21j9sf3 75 3 of of IN cord-292559-b21j9sf3 75 4 the the DT cord-292559-b21j9sf3 75 5 substance substance NN cord-292559-b21j9sf3 75 6 use use NN cord-292559-b21j9sf3 75 7 assessment assessment NN cord-292559-b21j9sf3 75 8 was be VBD cord-292559-b21j9sf3 75 9 to to TO cord-292559-b21j9sf3 75 10 start start VB cord-292559-b21j9sf3 75 11 with with IN cord-292559-b21j9sf3 75 12 the the DT cord-292559-b21j9sf3 75 13 very very RB cord-292559-b21j9sf3 75 14 earliest early JJS cord-292559-b21j9sf3 75 15 indicators indicator NNS cord-292559-b21j9sf3 75 16 of of IN cord-292559-b21j9sf3 75 17 exposure exposure NN cord-292559-b21j9sf3 75 18 to to IN cord-292559-b21j9sf3 75 19 and and CC cord-292559-b21j9sf3 75 20 knowledge knowledge NN cord-292559-b21j9sf3 75 21 about about IN cord-292559-b21j9sf3 75 22 substances substance NNS cord-292559-b21j9sf3 75 23 , , , cord-292559-b21j9sf3 75 24 and and CC cord-292559-b21j9sf3 75 25 then then RB cord-292559-b21j9sf3 75 26 to to TO cord-292559-b21j9sf3 75 27 capture capture VB cord-292559-b21j9sf3 75 28 the the DT cord-292559-b21j9sf3 75 29 onset onset NN cord-292559-b21j9sf3 75 30 , , , cord-292559-b21j9sf3 75 31 timing timing NN cord-292559-b21j9sf3 75 32 , , , cord-292559-b21j9sf3 75 33 and and CC cord-292559-b21j9sf3 75 34 quantity quantity NN cord-292559-b21j9sf3 75 35 of of IN cord-292559-b21j9sf3 75 36 any any DT cord-292559-b21j9sf3 75 37 substance substance NN cord-292559-b21j9sf3 75 38 use use NN cord-292559-b21j9sf3 75 39 that that WDT cord-292559-b21j9sf3 75 40 emerges emerge VBZ cord-292559-b21j9sf3 75 41 during during IN cord-292559-b21j9sf3 75 42 the the DT cord-292559-b21j9sf3 75 43 course course NN cord-292559-b21j9sf3 75 44 of of IN cord-292559-b21j9sf3 75 45 the the DT cord-292559-b21j9sf3 75 46 ABCD ABCD NNP cord-292559-b21j9sf3 75 47 Study Study NNP cord-292559-b21j9sf3 75 48 data datum NNS cord-292559-b21j9sf3 75 49 collection collection NN cord-292559-b21j9sf3 75 50 . . . cord-292559-b21j9sf3 76 1 A a DT cord-292559-b21j9sf3 76 2 variety variety NN cord-292559-b21j9sf3 76 3 of of IN cord-292559-b21j9sf3 76 4 measures measure NNS cord-292559-b21j9sf3 76 5 collected collect VBN cord-292559-b21j9sf3 76 6 from from IN cord-292559-b21j9sf3 76 7 youth youth NN cord-292559-b21j9sf3 76 8 are be VBP cord-292559-b21j9sf3 76 9 used use VBN cord-292559-b21j9sf3 76 10 to to TO cord-292559-b21j9sf3 76 11 accomplish accomplish VB cord-292559-b21j9sf3 76 12 this this DT cord-292559-b21j9sf3 76 13 goal goal NN cord-292559-b21j9sf3 76 14 , , , cord-292559-b21j9sf3 76 15 with with IN cord-292559-b21j9sf3 76 16 a a DT cord-292559-b21j9sf3 76 17 central central JJ cord-292559-b21j9sf3 76 18 one one NN cord-292559-b21j9sf3 76 19 being be VBG cord-292559-b21j9sf3 76 20 the the DT cord-292559-b21j9sf3 76 21 Timeline Timeline NNP cord-292559-b21j9sf3 76 22 Followback Followback NNP cord-292559-b21j9sf3 76 23 interview interview NN cord-292559-b21j9sf3 76 24 [ [ -LRB- cord-292559-b21j9sf3 76 25 19 19 CD cord-292559-b21j9sf3 76 26 , , , cord-292559-b21j9sf3 76 27 20 20 CD cord-292559-b21j9sf3 76 28 ] ] -RRB- cord-292559-b21j9sf3 76 29 designed design VBN cord-292559-b21j9sf3 76 30 to to TO cord-292559-b21j9sf3 76 31 establish establish VB cord-292559-b21j9sf3 76 32 the the DT cord-292559-b21j9sf3 76 33 specifics specific NNS cord-292559-b21j9sf3 76 34 of of IN cord-292559-b21j9sf3 76 35 substance substance NN cord-292559-b21j9sf3 76 36 use use VBP cord-292559-b21j9sf3 76 37 onset onset NN cord-292559-b21j9sf3 76 38 and and CC cord-292559-b21j9sf3 76 39 timing timing NN cord-292559-b21j9sf3 76 40 . . . cord-292559-b21j9sf3 77 1 Factors factor NNS cord-292559-b21j9sf3 77 2 impacting impact VBG cord-292559-b21j9sf3 77 3 substance substance NN cord-292559-b21j9sf3 77 4 use use NN cord-292559-b21j9sf3 77 5 are be VBP cord-292559-b21j9sf3 77 6 also also RB cord-292559-b21j9sf3 77 7 assessed assess VBN cord-292559-b21j9sf3 77 8 , , , cord-292559-b21j9sf3 77 9 including include VBG cord-292559-b21j9sf3 77 10 assessments assessment NNS cord-292559-b21j9sf3 77 11 about about IN cord-292559-b21j9sf3 77 12 intentions intention NNS cord-292559-b21j9sf3 77 13 to to TO cord-292559-b21j9sf3 77 14 use use VB cord-292559-b21j9sf3 77 15 , , , cord-292559-b21j9sf3 77 16 expectations expectation NNS cord-292559-b21j9sf3 77 17 about about IN cord-292559-b21j9sf3 77 18 substance substance NN cord-292559-b21j9sf3 77 19 effects effect NNS cord-292559-b21j9sf3 77 20 , , , cord-292559-b21j9sf3 77 21 curiosity curiosity NN cord-292559-b21j9sf3 77 22 , , , cord-292559-b21j9sf3 77 23 and and CC cord-292559-b21j9sf3 77 24 motivations motivation NNS cord-292559-b21j9sf3 77 25 regarding regard VBG cord-292559-b21j9sf3 77 26 substances substance NNS cord-292559-b21j9sf3 77 27 , , , cord-292559-b21j9sf3 77 28 perceptions perception NNS cord-292559-b21j9sf3 77 29 about about IN cord-292559-b21j9sf3 77 30 peer peer NN cord-292559-b21j9sf3 77 31 beliefs belief NNS cord-292559-b21j9sf3 77 32 regarding regard VBG cord-292559-b21j9sf3 77 33 substances substance NNS cord-292559-b21j9sf3 77 34 , , , cord-292559-b21j9sf3 77 35 assessment assessment NN cord-292559-b21j9sf3 77 36 of of IN cord-292559-b21j9sf3 77 37 sibling sibling NN cord-292559-b21j9sf3 77 38 use use NN cord-292559-b21j9sf3 77 39 , , , cord-292559-b21j9sf3 77 40 and and CC cord-292559-b21j9sf3 77 41 community community NN cord-292559-b21j9sf3 77 42 risk risk NN cord-292559-b21j9sf3 77 43 and and CC cord-292559-b21j9sf3 77 44 protective protective JJ cord-292559-b21j9sf3 77 45 factors factor NNS cord-292559-b21j9sf3 77 46 . . . cord-292559-b21j9sf3 78 1 Further further RB cord-292559-b21j9sf3 78 2 , , , cord-292559-b21j9sf3 78 3 parents parent NNS cord-292559-b21j9sf3 78 4 are be VBP cord-292559-b21j9sf3 78 5 asked ask VBN cord-292559-b21j9sf3 78 6 about about IN cord-292559-b21j9sf3 78 7 their -PRON- PRP$ cord-292559-b21j9sf3 78 8 youth youth NN cord-292559-b21j9sf3 78 9 's 's POS cord-292559-b21j9sf3 78 10 substance substance NN cord-292559-b21j9sf3 78 11 use use NN cord-292559-b21j9sf3 78 12 , , , cord-292559-b21j9sf3 78 13 family family NN cord-292559-b21j9sf3 78 14 rules rule VBZ cord-292559-b21j9sf3 78 15 about about IN cord-292559-b21j9sf3 78 16 substance substance NN cord-292559-b21j9sf3 78 17 use use NN cord-292559-b21j9sf3 78 18 , , , cord-292559-b21j9sf3 78 19 availability availability NN cord-292559-b21j9sf3 78 20 of of IN cord-292559-b21j9sf3 78 21 substances substance NNS cord-292559-b21j9sf3 78 22 in in IN cord-292559-b21j9sf3 78 23 the the DT cord-292559-b21j9sf3 78 24 environment environment NN cord-292559-b21j9sf3 78 25 , , , cord-292559-b21j9sf3 78 26 and and CC cord-292559-b21j9sf3 78 27 a a DT cord-292559-b21j9sf3 78 28 range range NN cord-292559-b21j9sf3 78 29 of of IN cord-292559-b21j9sf3 78 30 community community NN cord-292559-b21j9sf3 78 31 risk risk NN cord-292559-b21j9sf3 78 32 and and CC cord-292559-b21j9sf3 78 33 protective protective JJ cord-292559-b21j9sf3 78 34 factors factor NNS cord-292559-b21j9sf3 78 35 . . . cord-292559-b21j9sf3 79 1 Lastly lastly RB cord-292559-b21j9sf3 79 2 , , , cord-292559-b21j9sf3 79 3 biospecimens biospecimens NNP cord-292559-b21j9sf3 79 4 ( ( -LRB- cord-292559-b21j9sf3 79 5 saliva saliva NN cord-292559-b21j9sf3 79 6 and and CC cord-292559-b21j9sf3 79 7 hair hair NN cord-292559-b21j9sf3 79 8 ) ) -RRB- cord-292559-b21j9sf3 79 9 are be VBP cord-292559-b21j9sf3 79 10 assessed assess VBN cord-292559-b21j9sf3 79 11 for for IN cord-292559-b21j9sf3 79 12 exposure exposure NN cord-292559-b21j9sf3 79 13 to to IN cord-292559-b21j9sf3 79 14 alcohol alcohol NN cord-292559-b21j9sf3 79 15 and and CC cord-292559-b21j9sf3 79 16 substances substance NNS cord-292559-b21j9sf3 79 17 . . . cord-292559-b21j9sf3 80 1 Mental mental JJ cord-292559-b21j9sf3 80 2 health health NN cord-292559-b21j9sf3 80 3 . . . cord-292559-b21j9sf3 81 1 For for IN cord-292559-b21j9sf3 81 2 an an DT cord-292559-b21j9sf3 81 3 overview overview NN cord-292559-b21j9sf3 81 4 of of IN cord-292559-b21j9sf3 81 5 all all DT cord-292559-b21j9sf3 81 6 measures measure NNS cord-292559-b21j9sf3 81 7 that that WDT cord-292559-b21j9sf3 81 8 started start VBD cord-292559-b21j9sf3 81 9 at at IN cord-292559-b21j9sf3 81 10 baseline baseline NN cord-292559-b21j9sf3 81 11 and and CC cord-292559-b21j9sf3 81 12 year year NN cord-292559-b21j9sf3 81 13 1 1 CD cord-292559-b21j9sf3 81 14 , , , cord-292559-b21j9sf3 81 15 please please UH cord-292559-b21j9sf3 81 16 see see VB cord-292559-b21j9sf3 81 17 ref ref NN cord-292559-b21j9sf3 81 18 . . . cord-292559-b21j9sf3 82 1 [ [ -LRB- cord-292559-b21j9sf3 82 2 1 1 CD cord-292559-b21j9sf3 82 3 ] ] -RRB- cord-292559-b21j9sf3 82 4 . . . cord-292559-b21j9sf3 83 1 The the DT cord-292559-b21j9sf3 83 2 goal goal NN cord-292559-b21j9sf3 83 3 of of IN cord-292559-b21j9sf3 83 4 the the DT cord-292559-b21j9sf3 83 5 mental mental JJ cord-292559-b21j9sf3 83 6 health health NN cord-292559-b21j9sf3 83 7 assessments assessment NNS cord-292559-b21j9sf3 83 8 is be VBZ cord-292559-b21j9sf3 83 9 capturing capture VBG cord-292559-b21j9sf3 83 10 categorical categorical JJ cord-292559-b21j9sf3 83 11 and and CC cord-292559-b21j9sf3 83 12 dimensional dimensional JJ cord-292559-b21j9sf3 83 13 assessments assessment NNS cord-292559-b21j9sf3 83 14 of of IN cord-292559-b21j9sf3 83 15 current current JJ cord-292559-b21j9sf3 83 16 and and CC cord-292559-b21j9sf3 83 17 past past JJ cord-292559-b21j9sf3 83 18 mental mental JJ cord-292559-b21j9sf3 83 19 health health NN cord-292559-b21j9sf3 83 20 from from IN cord-292559-b21j9sf3 83 21 the the DT cord-292559-b21j9sf3 83 22 parent parent NN cord-292559-b21j9sf3 83 23 and and CC cord-292559-b21j9sf3 83 24 youth youth NN cord-292559-b21j9sf3 83 25 perspective perspective NN cord-292559-b21j9sf3 83 26 , , , cord-292559-b21j9sf3 83 27 as as RB cord-292559-b21j9sf3 83 28 well well RB cord-292559-b21j9sf3 83 29 as as IN cord-292559-b21j9sf3 83 30 teacher teacher NN cord-292559-b21j9sf3 83 31 perspective perspective NN cord-292559-b21j9sf3 83 32 , , , cord-292559-b21j9sf3 83 33 and and CC cord-292559-b21j9sf3 83 34 assessing assess VBG cord-292559-b21j9sf3 83 35 traits trait NNS cord-292559-b21j9sf3 83 36 and and CC cord-292559-b21j9sf3 83 37 characteristics characteristic NNS cord-292559-b21j9sf3 83 38 relevant relevant JJ cord-292559-b21j9sf3 83 39 to to IN cord-292559-b21j9sf3 83 40 understanding understand VBG cord-292559-b21j9sf3 83 41 risk risk NN cord-292559-b21j9sf3 83 42 trajectories trajectory NNS cord-292559-b21j9sf3 83 43 for for IN cord-292559-b21j9sf3 83 44 mental mental JJ cord-292559-b21j9sf3 83 45 health health NN cord-292559-b21j9sf3 83 46 . . . cord-292559-b21j9sf3 84 1 The the DT cord-292559-b21j9sf3 84 2 core core NN cord-292559-b21j9sf3 84 3 of of IN cord-292559-b21j9sf3 84 4 the the DT cord-292559-b21j9sf3 84 5 categorical categorical JJ cord-292559-b21j9sf3 84 6 assessment assessment NN cord-292559-b21j9sf3 84 7 of of IN cord-292559-b21j9sf3 84 8 youth youth NN cord-292559-b21j9sf3 84 9 mental mental NNP cord-292559-b21j9sf3 84 10 health health NNP cord-292559-b21j9sf3 84 11 is be VBZ cord-292559-b21j9sf3 84 12 the the DT cord-292559-b21j9sf3 84 13 new new JJ cord-292559-b21j9sf3 84 14 computerized computerized JJ cord-292559-b21j9sf3 84 15 Kiddie Kiddie NNP cord-292559-b21j9sf3 84 16 - - HYPH cord-292559-b21j9sf3 84 17 Structured Structured NNP cord-292559-b21j9sf3 84 18 Assessment Assessment NNP cord-292559-b21j9sf3 84 19 for for IN cord-292559-b21j9sf3 84 20 Affecitive Affecitive NNP cord-292559-b21j9sf3 84 21 Disorders Disorders NNPS cord-292559-b21j9sf3 84 22 and and CC cord-292559-b21j9sf3 84 23 Schizophrenia Schizophrenia NNP cord-292559-b21j9sf3 84 24 ( ( -LRB- cord-292559-b21j9sf3 84 25 KSADS KSADS NNP cord-292559-b21j9sf3 84 26 ) ) -RRB- cord-292559-b21j9sf3 84 27 , , , cord-292559-b21j9sf3 84 28 used use VBD cord-292559-b21j9sf3 84 29 to to TO cord-292559-b21j9sf3 84 30 assess assess VB cord-292559-b21j9sf3 84 31 parent parent NN cord-292559-b21j9sf3 84 32 - - HYPH cord-292559-b21j9sf3 84 33 report report NN cord-292559-b21j9sf3 84 34 of of IN cord-292559-b21j9sf3 84 35 youth youth NNP cord-292559-b21j9sf3 84 36 mental mental NNP cord-292559-b21j9sf3 84 37 health health NNP cord-292559-b21j9sf3 84 38 as as RB cord-292559-b21j9sf3 84 39 well well RB cord-292559-b21j9sf3 84 40 as as IN cord-292559-b21j9sf3 84 41 youth youth NN cord-292559-b21j9sf3 84 42 's 's POS cord-292559-b21j9sf3 84 43 self self NN cord-292559-b21j9sf3 84 44 - - HYPH cord-292559-b21j9sf3 84 45 report report NN cord-292559-b21j9sf3 84 46 [ [ -LRB- cord-292559-b21j9sf3 84 47 21 21 CD cord-292559-b21j9sf3 84 48 ] ] -RRB- cord-292559-b21j9sf3 84 49 [ [ -LRB- cord-292559-b21j9sf3 84 50 22 22 CD cord-292559-b21j9sf3 84 51 ] ] -RRB- cord-292559-b21j9sf3 84 52 [ [ -LRB- cord-292559-b21j9sf3 84 53 23 23 CD cord-292559-b21j9sf3 84 54 ] ] -RRB- cord-292559-b21j9sf3 84 55 . . . cord-292559-b21j9sf3 85 1 This this DT cord-292559-b21j9sf3 85 2 version version NN cord-292559-b21j9sf3 85 3 of of IN cord-292559-b21j9sf3 85 4 the the DT cord-292559-b21j9sf3 85 5 KSADs ksad NNS cord-292559-b21j9sf3 85 6 is be VBZ cord-292559-b21j9sf3 85 7 not not RB cord-292559-b21j9sf3 85 8 clinician clinician NN cord-292559-b21j9sf3 85 9 administered administer VBN cord-292559-b21j9sf3 85 10 , , , cord-292559-b21j9sf3 85 11 though though IN cord-292559-b21j9sf3 85 12 youth youth NN cord-292559-b21j9sf3 85 13 are be VBP cord-292559-b21j9sf3 85 14 aided aid VBN cord-292559-b21j9sf3 85 15 by by IN cord-292559-b21j9sf3 85 16 research research NN cord-292559-b21j9sf3 85 17 assistants assistant NNS cord-292559-b21j9sf3 85 18 . . . cord-292559-b21j9sf3 86 1 In in IN cord-292559-b21j9sf3 86 2 early early JJ cord-292559-b21j9sf3 86 3 ABCD ABCD NNP cord-292559-b21j9sf3 86 4 Study Study NNP cord-292559-b21j9sf3 86 5 assessment assessment NN cord-292559-b21j9sf3 86 6 waves wave NNS cord-292559-b21j9sf3 86 7 , , , cord-292559-b21j9sf3 86 8 most most JJS cord-292559-b21j9sf3 86 9 modules module NNS cord-292559-b21j9sf3 86 10 are be VBP cord-292559-b21j9sf3 86 11 completed complete VBN cord-292559-b21j9sf3 86 12 by by IN cord-292559-b21j9sf3 86 13 a a DT cord-292559-b21j9sf3 86 14 parent parent NN cord-292559-b21j9sf3 86 15 / / SYM cord-292559-b21j9sf3 86 16 caregiver caregiver NN cord-292559-b21j9sf3 86 17 ( ( -LRB- cord-292559-b21j9sf3 86 18 mood mood NN cord-292559-b21j9sf3 86 19 , , , cord-292559-b21j9sf3 86 20 psychosis psychosis NN cord-292559-b21j9sf3 86 21 , , , cord-292559-b21j9sf3 86 22 anxiety anxiety NN cord-292559-b21j9sf3 86 23 , , , cord-292559-b21j9sf3 86 24 externalizing externalizing NN cord-292559-b21j9sf3 86 25 , , , cord-292559-b21j9sf3 86 26 sleep sleep NN cord-292559-b21j9sf3 86 27 , , , cord-292559-b21j9sf3 86 28 and and CC cord-292559-b21j9sf3 86 29 suicidality suicidality NN cord-292559-b21j9sf3 86 30 ) ) -RRB- cord-292559-b21j9sf3 86 31 , , , cord-292559-b21j9sf3 86 32 with with IN cord-292559-b21j9sf3 86 33 a a DT cord-292559-b21j9sf3 86 34 subset subset NN cord-292559-b21j9sf3 86 35 also also RB cord-292559-b21j9sf3 86 36 completed complete VBN cord-292559-b21j9sf3 86 37 by by IN cord-292559-b21j9sf3 86 38 youth youth NN cord-292559-b21j9sf3 86 39 ( ( -LRB- cord-292559-b21j9sf3 86 40 mood mood NN cord-292559-b21j9sf3 86 41 , , , cord-292559-b21j9sf3 86 42 anxiety anxiety NN cord-292559-b21j9sf3 86 43 , , , cord-292559-b21j9sf3 86 44 sleep sleep NN cord-292559-b21j9sf3 86 45 , , , cord-292559-b21j9sf3 86 46 and and CC cord-292559-b21j9sf3 86 47 suicidality suicidality NN cord-292559-b21j9sf3 86 48 ) ) -RRB- cord-292559-b21j9sf3 86 49 , , , cord-292559-b21j9sf3 86 50 with with IN cord-292559-b21j9sf3 86 51 the the DT cord-292559-b21j9sf3 86 52 number number NN cord-292559-b21j9sf3 86 53 of of IN cord-292559-b21j9sf3 86 54 modules module NNS cord-292559-b21j9sf3 86 55 completed complete VBN cord-292559-b21j9sf3 86 56 by by IN cord-292559-b21j9sf3 86 57 youth youth NN cord-292559-b21j9sf3 86 58 increasing increase VBG cord-292559-b21j9sf3 86 59 across across IN cord-292559-b21j9sf3 86 60 the the DT cord-292559-b21j9sf3 86 61 course course NN cord-292559-b21j9sf3 86 62 of of IN cord-292559-b21j9sf3 86 63 the the DT cord-292559-b21j9sf3 86 64 study study NN cord-292559-b21j9sf3 86 65 as as IN cord-292559-b21j9sf3 86 66 developmentally developmentally RB cord-292559-b21j9sf3 86 67 appropriate appropriate JJ cord-292559-b21j9sf3 86 68 . . . cord-292559-b21j9sf3 87 1 A a DT cord-292559-b21j9sf3 87 2 range range NN cord-292559-b21j9sf3 87 3 of of IN cord-292559-b21j9sf3 87 4 dimensional dimensional JJ cord-292559-b21j9sf3 87 5 measures measure NNS cord-292559-b21j9sf3 87 6 of of IN cord-292559-b21j9sf3 87 7 mental mental JJ cord-292559-b21j9sf3 87 8 health health NN cord-292559-b21j9sf3 87 9 are be VBP cord-292559-b21j9sf3 87 10 completed complete VBN cord-292559-b21j9sf3 87 11 by by IN cord-292559-b21j9sf3 87 12 either either DT cord-292559-b21j9sf3 87 13 or or CC cord-292559-b21j9sf3 87 14 both both CC cord-292559-b21j9sf3 87 15 the the DT cord-292559-b21j9sf3 87 16 parent parent NN cord-292559-b21j9sf3 87 17 / / SYM cord-292559-b21j9sf3 87 18 caregiver caregiver NN cord-292559-b21j9sf3 87 19 and and CC cord-292559-b21j9sf3 87 20 youth youth NN cord-292559-b21j9sf3 87 21 , , , cord-292559-b21j9sf3 87 22 and and CC cord-292559-b21j9sf3 87 23 the the DT cord-292559-b21j9sf3 87 24 core core NN cord-292559-b21j9sf3 87 25 of of IN cord-292559-b21j9sf3 87 26 these these DT cord-292559-b21j9sf3 87 27 dimensional dimensional JJ cord-292559-b21j9sf3 87 28 assessments assessment NNS cord-292559-b21j9sf3 87 29 is be VBZ cord-292559-b21j9sf3 87 30 the the DT cord-292559-b21j9sf3 87 31 Achenbach Achenbach NNP cord-292559-b21j9sf3 87 32 system system NN cord-292559-b21j9sf3 87 33 of of IN cord-292559-b21j9sf3 87 34 emprically emprically RB cord-292559-b21j9sf3 87 35 based base VBN cord-292559-b21j9sf3 87 36 assessment assessment NN cord-292559-b21j9sf3 87 37 ( ( -LRB- cord-292559-b21j9sf3 87 38 ASEBA ASEBA NNP cord-292559-b21j9sf3 87 39 ) ) -RRB- cord-292559-b21j9sf3 87 40 system system NN cord-292559-b21j9sf3 87 41 [ [ -LRB- cord-292559-b21j9sf3 87 42 24 24 CD cord-292559-b21j9sf3 87 43 , , , cord-292559-b21j9sf3 87 44 25 25 CD cord-292559-b21j9sf3 87 45 ] ] -RRB- cord-292559-b21j9sf3 87 46 generously generously RB cord-292559-b21j9sf3 87 47 provided provide VBN cord-292559-b21j9sf3 87 48 at at IN cord-292559-b21j9sf3 87 49 no no DT cord-292559-b21j9sf3 87 50 cost cost NN cord-292559-b21j9sf3 87 51 to to IN cord-292559-b21j9sf3 87 52 the the DT cord-292559-b21j9sf3 87 53 ABCD ABCD NNP cord-292559-b21j9sf3 87 54 Study Study NNP cord-292559-b21j9sf3 87 55 . . . cord-292559-b21j9sf3 88 1 The the DT cord-292559-b21j9sf3 88 2 parent/ parent/ JJ cord-292559-b21j9sf3 88 3 caregiver caregiver NN cord-292559-b21j9sf3 88 4 annually annually RB cord-292559-b21j9sf3 88 5 completes complete VBZ cord-292559-b21j9sf3 88 6 the the DT cord-292559-b21j9sf3 88 7 Child Child NNP cord-292559-b21j9sf3 88 8 Behavioral Behavioral NNP cord-292559-b21j9sf3 88 9 Checklist Checklist NNP cord-292559-b21j9sf3 88 10 as as IN cord-292559-b21j9sf3 88 11 a a DT cord-292559-b21j9sf3 88 12 broad broad JJ cord-292559-b21j9sf3 88 13 dimensional dimensional JJ cord-292559-b21j9sf3 88 14 assessment assessment NN cord-292559-b21j9sf3 88 15 of of IN cord-292559-b21j9sf3 88 16 youth youth NN cord-292559-b21j9sf3 88 17 mental mental NNP cord-292559-b21j9sf3 88 18 health health NNP cord-292559-b21j9sf3 88 19 . . . cord-292559-b21j9sf3 89 1 The the DT cord-292559-b21j9sf3 89 2 parent parent NN cord-292559-b21j9sf3 89 3 / / SYM cord-292559-b21j9sf3 89 4 caregiver caregiver NN cord-292559-b21j9sf3 89 5 also also RB cord-292559-b21j9sf3 89 6 completes complete VBZ cord-292559-b21j9sf3 89 7 additional additional JJ cord-292559-b21j9sf3 89 8 measures measure NNS cord-292559-b21j9sf3 89 9 of of IN cord-292559-b21j9sf3 89 10 early early JJ cord-292559-b21j9sf3 89 11 signs sign NNS cord-292559-b21j9sf3 89 12 of of IN cord-292559-b21j9sf3 89 13 mania mania NN cord-292559-b21j9sf3 89 14 and and CC cord-292559-b21j9sf3 89 15 autism autism NN cord-292559-b21j9sf3 89 16 spectrum spectrum NN cord-292559-b21j9sf3 89 17 symptoms symptom NNS cord-292559-b21j9sf3 89 18 , , , cord-292559-b21j9sf3 89 19 youth youth NN cord-292559-b21j9sf3 89 20 temperament temperament NN cord-292559-b21j9sf3 89 21 , , , cord-292559-b21j9sf3 89 22 life life NN cord-292559-b21j9sf3 89 23 events event NNS cord-292559-b21j9sf3 89 24 , , , cord-292559-b21j9sf3 89 25 and and CC cord-292559-b21j9sf3 89 26 emotion emotion NN cord-292559-b21j9sf3 89 27 regulation regulation NN cord-292559-b21j9sf3 89 28 abilities ability NNS cord-292559-b21j9sf3 89 29 , , , cord-292559-b21j9sf3 89 30 the the DT cord-292559-b21j9sf3 89 31 family family NN cord-292559-b21j9sf3 89 32 's 's POS cord-292559-b21j9sf3 89 33 mental mental JJ cord-292559-b21j9sf3 89 34 health health NN cord-292559-b21j9sf3 89 35 history history NN cord-292559-b21j9sf3 89 36 , , , cord-292559-b21j9sf3 89 37 and and CC cord-292559-b21j9sf3 89 38 their -PRON- PRP$ cord-292559-b21j9sf3 89 39 own own JJ cord-292559-b21j9sf3 89 40 mental mental JJ cord-292559-b21j9sf3 89 41 health health NN cord-292559-b21j9sf3 89 42 and and CC cord-292559-b21j9sf3 89 43 stress stress NN cord-292559-b21j9sf3 89 44 . . . cord-292559-b21j9sf3 90 1 The the DT cord-292559-b21j9sf3 90 2 youth youth NN cord-292559-b21j9sf3 90 3 completes complete VBZ cord-292559-b21j9sf3 90 4 additional additional JJ cord-292559-b21j9sf3 90 5 measures measure NNS cord-292559-b21j9sf3 90 6 of of IN cord-292559-b21j9sf3 90 7 psychotic psychotic JJ cord-292559-b21j9sf3 90 8 - - HYPH cord-292559-b21j9sf3 90 9 like like JJ cord-292559-b21j9sf3 90 10 experiences experience NNS cord-292559-b21j9sf3 90 11 ( ( -LRB- cord-292559-b21j9sf3 90 12 PLEs PLEs NNP cord-292559-b21j9sf3 90 13 ) ) -RRB- cord-292559-b21j9sf3 90 14 , , , cord-292559-b21j9sf3 90 15 mania mania NN cord-292559-b21j9sf3 90 16 , , , cord-292559-b21j9sf3 90 17 and and CC cord-292559-b21j9sf3 90 18 conduct conduct VB cord-292559-b21j9sf3 90 19 disorder disorder NN cord-292559-b21j9sf3 90 20 , , , cord-292559-b21j9sf3 90 21 as as RB cord-292559-b21j9sf3 90 22 well well RB cord-292559-b21j9sf3 90 23 as as IN cord-292559-b21j9sf3 90 24 personality personality NN cord-292559-b21j9sf3 90 25 traits trait NNS cord-292559-b21j9sf3 90 26 ( ( -LRB- cord-292559-b21j9sf3 90 27 e.g. e.g. RB cord-292559-b21j9sf3 90 28 , , , cord-292559-b21j9sf3 90 29 impulsivity impulsivity NN cord-292559-b21j9sf3 90 30 , , , cord-292559-b21j9sf3 90 31 behavioral behavioral JJ cord-292559-b21j9sf3 90 32 activation activation NN cord-292559-b21j9sf3 90 33 and and CC cord-292559-b21j9sf3 90 34 inhibition inhibition NN cord-292559-b21j9sf3 90 35 , , , cord-292559-b21j9sf3 90 36 and and CC cord-292559-b21j9sf3 90 37 emotion emotion NN cord-292559-b21j9sf3 90 38 regulation regulation NN cord-292559-b21j9sf3 90 39 ) ) -RRB- cord-292559-b21j9sf3 90 40 and and CC cord-292559-b21j9sf3 90 41 relevant relevant JJ cord-292559-b21j9sf3 90 42 experiences experience NNS cord-292559-b21j9sf3 90 43 , , , cord-292559-b21j9sf3 90 44 including include VBG cord-292559-b21j9sf3 90 45 friendships friendship NNS cord-292559-b21j9sf3 90 46 , , , cord-292559-b21j9sf3 90 47 peer peer NN cord-292559-b21j9sf3 90 48 relationships relationship NNS cord-292559-b21j9sf3 90 49 , , , cord-292559-b21j9sf3 90 50 bullying bullying NN cord-292559-b21j9sf3 90 51 , , , cord-292559-b21j9sf3 90 52 and and CC cord-292559-b21j9sf3 90 53 life life NN cord-292559-b21j9sf3 90 54 events event NNS cord-292559-b21j9sf3 90 55 . . . cord-292559-b21j9sf3 91 1 The the DT cord-292559-b21j9sf3 91 2 youth youth NN cord-292559-b21j9sf3 91 3 completes complete VBZ cord-292559-b21j9sf3 91 4 the the DT cord-292559-b21j9sf3 91 5 ASEBA ASEBA NNP cord-292559-b21j9sf3 91 6 Brief Brief NNP cord-292559-b21j9sf3 91 7 Problem Problem NNP cord-292559-b21j9sf3 91 8 Monitor Monitor NNP cord-292559-b21j9sf3 91 9 ( ( -LRB- cord-292559-b21j9sf3 91 10 BPM BPM NNP cord-292559-b21j9sf3 91 11 ) ) -RRB- cord-292559-b21j9sf3 91 12 every every DT cord-292559-b21j9sf3 91 13 6 6 CD cord-292559-b21j9sf3 91 14 months month NNS cord-292559-b21j9sf3 91 15 . . . cord-292559-b21j9sf3 92 1 Lastly lastly RB cord-292559-b21j9sf3 92 2 , , , cord-292559-b21j9sf3 92 3 teachers teacher NNS cord-292559-b21j9sf3 92 4 are be VBP cord-292559-b21j9sf3 92 5 also also RB cord-292559-b21j9sf3 92 6 asked ask VBN cord-292559-b21j9sf3 92 7 to to TO cord-292559-b21j9sf3 92 8 report report VB cord-292559-b21j9sf3 92 9 on on IN cord-292559-b21j9sf3 92 10 youth youth NN cord-292559-b21j9sf3 92 11 mental mental NNP cord-292559-b21j9sf3 92 12 health health NN cord-292559-b21j9sf3 92 13 using use VBG cord-292559-b21j9sf3 92 14 the the DT cord-292559-b21j9sf3 92 15 BPM BPM NNP cord-292559-b21j9sf3 92 16 for for IN cord-292559-b21j9sf3 92 17 Teachers teacher NNS cord-292559-b21j9sf3 92 18 . . . cord-292559-b21j9sf3 93 1 Physical physical JJ cord-292559-b21j9sf3 93 2 health health NN cord-292559-b21j9sf3 93 3 and and CC cord-292559-b21j9sf3 93 4 biospecimens biospecimens NNP cord-292559-b21j9sf3 93 5 / / SYM cord-292559-b21j9sf3 93 6 genetics genetic NNS cord-292559-b21j9sf3 93 7 . . . cord-292559-b21j9sf3 94 1 For for IN cord-292559-b21j9sf3 94 2 an an DT cord-292559-b21j9sf3 94 3 overview overview NN cord-292559-b21j9sf3 94 4 of of IN cord-292559-b21j9sf3 94 5 all all DT cord-292559-b21j9sf3 94 6 measures measure NNS cord-292559-b21j9sf3 94 7 that that WDT cord-292559-b21j9sf3 94 8 started start VBD cord-292559-b21j9sf3 94 9 at at IN cord-292559-b21j9sf3 94 10 baseline baseline NN cord-292559-b21j9sf3 94 11 and and CC cord-292559-b21j9sf3 94 12 year year NN cord-292559-b21j9sf3 94 13 1 1 CD cord-292559-b21j9sf3 94 14 , , , cord-292559-b21j9sf3 94 15 please please UH cord-292559-b21j9sf3 94 16 see see VB cord-292559-b21j9sf3 94 17 ref ref NN cord-292559-b21j9sf3 94 18 . . . cord-292559-b21j9sf3 95 1 [ [ -LRB- cord-292559-b21j9sf3 95 2 1 1 CD cord-292559-b21j9sf3 95 3 ] ] -RRB- cord-292559-b21j9sf3 95 4 . . . cord-292559-b21j9sf3 96 1 This this DT cord-292559-b21j9sf3 96 2 assessment assessment NN cord-292559-b21j9sf3 96 3 includes include VBZ cord-292559-b21j9sf3 96 4 a a DT cord-292559-b21j9sf3 96 5 lifetime lifetime NN cord-292559-b21j9sf3 96 6 medical medical JJ cord-292559-b21j9sf3 96 7 , , , cord-292559-b21j9sf3 96 8 head head NN cord-292559-b21j9sf3 96 9 injury injury NN cord-292559-b21j9sf3 96 10 , , , cord-292559-b21j9sf3 96 11 and and CC cord-292559-b21j9sf3 96 12 developmental developmental JJ cord-292559-b21j9sf3 96 13 history history NN cord-292559-b21j9sf3 96 14 for for IN cord-292559-b21j9sf3 96 15 the the DT cord-292559-b21j9sf3 96 16 youth youth NN cord-292559-b21j9sf3 96 17 provided provide VBN cord-292559-b21j9sf3 96 18 by by IN cord-292559-b21j9sf3 96 19 the the DT cord-292559-b21j9sf3 96 20 parent/ parent/ JJ cord-292559-b21j9sf3 96 21 = = NFP cord-292559-b21j9sf3 97 1 NIH NIH NNP cord-292559-b21j9sf3 97 2 Toobox Toobox NNP cord-292559-b21j9sf3 97 3 ; ; : cord-292559-b21j9sf3 97 4 = = SYM cord-292559-b21j9sf3 97 5 " " `` cord-292559-b21j9sf3 97 6 cold cold JJ cord-292559-b21j9sf3 97 7 " " '' cord-292559-b21j9sf3 97 8 cogn cogn NNS cord-292559-b21j9sf3 98 1 nitive nitive NNP cord-292559-b21j9sf3 98 2 e e NNP cord-292559-b21j9sf3 99 1 me -PRON- PRP cord-292559-b21j9sf3 99 2 easures easures NNP cord-292559-b21j9sf3 100 1 ; ; : cord-292559-b21j9sf3 100 2 = = SYM cord-292559-b21j9sf3 100 3 " " `` cord-292559-b21j9sf3 100 4 hot hot JJ cord-292559-b21j9sf3 100 5 " " '' cord-292559-b21j9sf3 100 6 c c NNP cord-292559-b21j9sf3 100 7 cogni cogni NNP cord-292559-b21j9sf3 100 8 itive itive FW cord-292559-b21j9sf3 100 9 mea mea FW cord-292559-b21j9sf3 100 10 asure asure NNP cord-292559-b21j9sf3 100 11 es es NNP cord-292559-b21j9sf3 100 12 ; ; : cord-292559-b21j9sf3 100 13 = = NFP cord-292559-b21j9sf3 100 14 = = NFP cord-292559-b21j9sf3 101 1 geo geo NNP cord-292559-b21j9sf3 101 2 ocode ocode NNP cord-292559-b21j9sf3 101 3 ed ed NNP cord-292559-b21j9sf3 101 4 factor factor NNP cord-292559-b21j9sf3 101 5 rs rs NNP cord-292559-b21j9sf3 101 6 ; ; : cord-292559-b21j9sf3 101 7 = = SYM cord-292559-b21j9sf3 101 8 b b NN cord-292559-b21j9sf3 101 9 brain brain NN cord-292559-b21j9sf3 101 10 imag imag NNP cord-292559-b21j9sf3 101 11 ging ging NNP cord-292559-b21j9sf3 101 12 The the DT cord-292559-b21j9sf3 101 13 ABCD ABCD NNP cord-292559-b21j9sf3 101 14 study study NN cord-292559-b21j9sf3 101 15 : : : cord-292559-b21j9sf3 101 16 understanding understand VBG cord-292559-b21j9sf3 101 17 the the DT cord-292559-b21j9sf3 101 18 development development NN cord-292559-b21j9sf3 101 19 of of IN cord-292559-b21j9sf3 101 20 risk risk NN cord-292559-b21j9sf3 101 21 for for IN cord-292559-b21j9sf3 101 22 mental mental JJ cord-292559-b21j9sf3 101 23 and and CC cord-292559-b21j9sf3 101 24 . . . cord-292559-b21j9sf3 101 25 . . . cord-292559-b21j9sf3 101 26 . . . cord-292559-b21j9sf3 102 1 NR NR NNP cord-292559-b21j9sf3 102 2 Karcher Karcher NNP cord-292559-b21j9sf3 102 3 and and CC cord-292559-b21j9sf3 102 4 DM DM NNP cord-292559-b21j9sf3 102 5 Barch Barch NNP cord-292559-b21j9sf3 102 6 caregiver caregiver NN cord-292559-b21j9sf3 102 7 at at IN cord-292559-b21j9sf3 102 8 baseline baseline NN cord-292559-b21j9sf3 102 9 , , , cord-292559-b21j9sf3 102 10 along along IN cord-292559-b21j9sf3 102 11 with with IN cord-292559-b21j9sf3 102 12 annual annual JJ cord-292559-b21j9sf3 102 13 updates update NNS cord-292559-b21j9sf3 102 14 about about IN cord-292559-b21j9sf3 102 15 medical medical JJ cord-292559-b21j9sf3 102 16 experiences experience NNS cord-292559-b21j9sf3 102 17 , , , cord-292559-b21j9sf3 102 18 medications medication NNS cord-292559-b21j9sf3 102 19 , , , cord-292559-b21j9sf3 102 20 and and CC cord-292559-b21j9sf3 102 21 head head NN cord-292559-b21j9sf3 102 22 injuries injury NNS cord-292559-b21j9sf3 102 23 ( ( -LRB- cord-292559-b21j9sf3 102 24 including include VBG cord-292559-b21j9sf3 102 25 sports sport NNS cord-292559-b21j9sf3 102 26 related relate VBN cord-292559-b21j9sf3 102 27 ) ) -RRB- cord-292559-b21j9sf3 102 28 . . . cord-292559-b21j9sf3 103 1 Both both DT cord-292559-b21j9sf3 103 2 the the DT cord-292559-b21j9sf3 103 3 parent parent NN cord-292559-b21j9sf3 103 4 / / SYM cord-292559-b21j9sf3 103 5 caregiver caregiver NN cord-292559-b21j9sf3 103 6 and and CC cord-292559-b21j9sf3 103 7 youth youth NN cord-292559-b21j9sf3 103 8 provide provide VBP cord-292559-b21j9sf3 103 9 annual annual JJ cord-292559-b21j9sf3 103 10 descriptions description NNS cord-292559-b21j9sf3 103 11 of of IN cord-292559-b21j9sf3 103 12 their -PRON- PRP$ cord-292559-b21j9sf3 103 13 pubertal pubertal JJ cord-292559-b21j9sf3 103 14 status status NN cord-292559-b21j9sf3 103 15 and and CC cord-292559-b21j9sf3 103 16 saliva saliva NN cord-292559-b21j9sf3 103 17 assessments assessment NNS cord-292559-b21j9sf3 103 18 of of IN cord-292559-b21j9sf3 103 19 pubertal pubertal JJ cord-292559-b21j9sf3 103 20 hormones hormone NNS cord-292559-b21j9sf3 103 21 ( ( -LRB- cord-292559-b21j9sf3 103 22 including include VBG cord-292559-b21j9sf3 103 23 assessing assess VBG cord-292559-b21j9sf3 103 24 levels level NNS cord-292559-b21j9sf3 103 25 of of IN cord-292559-b21j9sf3 103 26 testosterone testosterone NN cord-292559-b21j9sf3 103 27 and and CC cord-292559-b21j9sf3 103 28 DHEA dhea NN cord-292559-b21j9sf3 103 29 in in IN cord-292559-b21j9sf3 103 30 males male NNS cord-292559-b21j9sf3 103 31 and and CC cord-292559-b21j9sf3 103 32 females female NNS cord-292559-b21j9sf3 103 33 , , , cord-292559-b21j9sf3 103 34 as as RB cord-292559-b21j9sf3 103 35 well well RB cord-292559-b21j9sf3 103 36 as as IN cord-292559-b21j9sf3 103 37 estradiol estradiol NN cord-292559-b21j9sf3 103 38 in in IN cord-292559-b21j9sf3 103 39 females female NNS cord-292559-b21j9sf3 103 40 ) ) -RRB- cord-292559-b21j9sf3 103 41 . . . cord-292559-b21j9sf3 104 1 Parent parent NN cord-292559-b21j9sf3 104 2 / / SYM cord-292559-b21j9sf3 104 3 caregiver caregiver NN cord-292559-b21j9sf3 104 4 and and CC cord-292559-b21j9sf3 104 5 youth youth NN cord-292559-b21j9sf3 104 6 also also RB cord-292559-b21j9sf3 104 7 report report VBP cord-292559-b21j9sf3 104 8 on on IN cord-292559-b21j9sf3 104 9 experiences experience NNS cord-292559-b21j9sf3 104 10 with with IN cord-292559-b21j9sf3 104 11 sleep sleep NN cord-292559-b21j9sf3 104 12 and and CC cord-292559-b21j9sf3 104 13 sleep sleep NN cord-292559-b21j9sf3 104 14 disorders disorder NNS cord-292559-b21j9sf3 104 15 , , , cord-292559-b21j9sf3 104 16 including include VBG cord-292559-b21j9sf3 104 17 youth youth NN cord-292559-b21j9sf3 104 18 reports report NNS cord-292559-b21j9sf3 104 19 of of IN cord-292559-b21j9sf3 104 20 sleep sleep NNP cord-292559-b21j9sf3 104 21 chronotypes chronotypes NNP cord-292559-b21j9sf3 104 22 , , , cord-292559-b21j9sf3 104 23 respiratory respiratory JJ cord-292559-b21j9sf3 104 24 function function NN cord-292559-b21j9sf3 104 25 , , , cord-292559-b21j9sf3 104 26 and and CC cord-292559-b21j9sf3 104 27 pain pain NN cord-292559-b21j9sf3 104 28 experiences experience NNS cord-292559-b21j9sf3 104 29 . . . cord-292559-b21j9sf3 105 1 The the DT cord-292559-b21j9sf3 105 2 youth youth NN cord-292559-b21j9sf3 105 3 and/or and/or CC cord-292559-b21j9sf3 105 4 their -PRON- PRP$ cord-292559-b21j9sf3 105 5 parent parent NN cord-292559-b21j9sf3 105 6 / / SYM cord-292559-b21j9sf3 105 7 caregiver caregiver NN cord-292559-b21j9sf3 105 8 provide provide VB cord-292559-b21j9sf3 105 9 annual annual JJ cord-292559-b21j9sf3 105 10 information information NN cord-292559-b21j9sf3 105 11 about about IN cord-292559-b21j9sf3 105 12 diet diet NN cord-292559-b21j9sf3 105 13 , , , cord-292559-b21j9sf3 105 14 frequency frequency NN cord-292559-b21j9sf3 105 15 of of IN cord-292559-b21j9sf3 105 16 exercise exercise NN cord-292559-b21j9sf3 105 17 , , , cord-292559-b21j9sf3 105 18 involvement involvement NN cord-292559-b21j9sf3 105 19 in in IN cord-292559-b21j9sf3 105 20 sports sport NNS cord-292559-b21j9sf3 105 21 and and CC cord-292559-b21j9sf3 105 22 other other JJ cord-292559-b21j9sf3 105 23 activities activity NNS cord-292559-b21j9sf3 105 24 , , , cord-292559-b21j9sf3 105 25 and and CC cord-292559-b21j9sf3 105 26 time time NN cord-292559-b21j9sf3 105 27 spent spend VBN cord-292559-b21j9sf3 105 28 using use VBG cord-292559-b21j9sf3 105 29 various various JJ cord-292559-b21j9sf3 105 30 types type NNS cord-292559-b21j9sf3 105 31 of of IN cord-292559-b21j9sf3 105 32 electronic electronic JJ cord-292559-b21j9sf3 105 33 media medium NNS cord-292559-b21j9sf3 105 34 , , , cord-292559-b21j9sf3 105 35 including include VBG cord-292559-b21j9sf3 105 36 TV tv NN cord-292559-b21j9sf3 105 37 , , , cord-292559-b21j9sf3 105 38 videos video NNS cord-292559-b21j9sf3 105 39 , , , cord-292559-b21j9sf3 105 40 social social JJ cord-292559-b21j9sf3 105 41 media medium NNS cord-292559-b21j9sf3 105 42 , , , cord-292559-b21j9sf3 105 43 etc etc FW cord-292559-b21j9sf3 105 44 . . . cord-292559-b21j9sf3 106 1 Further further RB cord-292559-b21j9sf3 106 2 , , , cord-292559-b21j9sf3 106 3 in in IN cord-292559-b21j9sf3 106 4 year year NN cord-292559-b21j9sf3 106 5 2 2 CD cord-292559-b21j9sf3 106 6 of of IN cord-292559-b21j9sf3 106 7 data datum NNS cord-292559-b21j9sf3 106 8 collection collection NN cord-292559-b21j9sf3 106 9 ( ( -LRB- cord-292559-b21j9sf3 106 10 youth youth NN cord-292559-b21j9sf3 106 11 = = SYM cord-292559-b21j9sf3 106 12 11 11 CD cord-292559-b21j9sf3 106 13 - - HYPH cord-292559-b21j9sf3 106 14 12-years 12-years CD cord-292559-b21j9sf3 106 15 - - HYPH cord-292559-b21j9sf3 106 16 old old JJ cord-292559-b21j9sf3 106 17 ) ) -RRB- cord-292559-b21j9sf3 106 18 , , , cord-292559-b21j9sf3 106 19 all all DT cord-292559-b21j9sf3 106 20 youth youth NN cord-292559-b21j9sf3 106 21 were be VBD cord-292559-b21j9sf3 106 22 asked ask VBN cord-292559-b21j9sf3 106 23 to to TO cord-292559-b21j9sf3 106 24 wear wear VB cord-292559-b21j9sf3 106 25 a a DT cord-292559-b21j9sf3 106 26 FitBit FitBit NNP cord-292559-b21j9sf3 106 27 for for IN cord-292559-b21j9sf3 106 28 2 2 CD cord-292559-b21j9sf3 106 29 weeks week NNS cord-292559-b21j9sf3 106 30 . . . cord-292559-b21j9sf3 107 1 Fitbits fitbit NNS cord-292559-b21j9sf3 107 2 provide provide VBP cord-292559-b21j9sf3 107 3 data datum NNS cord-292559-b21j9sf3 107 4 on on IN cord-292559-b21j9sf3 107 5 heart heart NN cord-292559-b21j9sf3 107 6 rate rate NN cord-292559-b21j9sf3 107 7 , , , cord-292559-b21j9sf3 107 8 physical physical JJ cord-292559-b21j9sf3 107 9 activity activity NN cord-292559-b21j9sf3 107 10 levels level NNS cord-292559-b21j9sf3 107 11 , , , cord-292559-b21j9sf3 107 12 and and CC cord-292559-b21j9sf3 107 13 sleep sleep NN cord-292559-b21j9sf3 107 14 . . . cord-292559-b21j9sf3 108 1 Biospecimens biospecimen NNS cord-292559-b21j9sf3 108 2 are be VBP cord-292559-b21j9sf3 108 3 collected collect VBN cord-292559-b21j9sf3 108 4 , , , cord-292559-b21j9sf3 108 5 including include VBG cord-292559-b21j9sf3 108 6 baby baby NN cord-292559-b21j9sf3 108 7 teeth tooth NNS cord-292559-b21j9sf3 108 8 , , , cord-292559-b21j9sf3 108 9 saliva saliva NN cord-292559-b21j9sf3 108 10 , , , cord-292559-b21j9sf3 108 11 hair hair NN cord-292559-b21j9sf3 108 12 , , , cord-292559-b21j9sf3 108 13 and and CC cord-292559-b21j9sf3 108 14 blood blood NN cord-292559-b21j9sf3 108 15 , , , cord-292559-b21j9sf3 108 16 for for IN cord-292559-b21j9sf3 108 17 purposes purpose NNS cord-292559-b21j9sf3 108 18 of of IN cord-292559-b21j9sf3 108 19 screening screening NN cord-292559-b21j9sf3 108 20 for for IN cord-292559-b21j9sf3 108 21 and and CC cord-292559-b21j9sf3 108 22 examining examine VBG cord-292559-b21j9sf3 108 23 effects effect NNS cord-292559-b21j9sf3 108 24 of of IN cord-292559-b21j9sf3 108 25 drug drug NN cord-292559-b21j9sf3 108 26 use use NN cord-292559-b21j9sf3 108 27 , , , cord-292559-b21j9sf3 108 28 assessing assess VBG cord-292559-b21j9sf3 108 29 pubertal pubertal JJ cord-292559-b21j9sf3 108 30 hormones hormone NNS cord-292559-b21j9sf3 108 31 , , , cord-292559-b21j9sf3 108 32 characterizing characterize VBG cord-292559-b21j9sf3 108 33 genetic genetic JJ cord-292559-b21j9sf3 108 34 and and CC cord-292559-b21j9sf3 108 35 epigenetic epigenetic JJ cord-292559-b21j9sf3 108 36 factors factor NNS cord-292559-b21j9sf3 108 37 , , , cord-292559-b21j9sf3 108 38 and and CC cord-292559-b21j9sf3 108 39 assessing assess VBG cord-292559-b21j9sf3 108 40 the the DT cord-292559-b21j9sf3 108 41 presence presence NN cord-292559-b21j9sf3 108 42 and and CC cord-292559-b21j9sf3 108 43 effects effect NNS cord-292559-b21j9sf3 108 44 of of IN cord-292559-b21j9sf3 108 45 exposure exposure NN cord-292559-b21j9sf3 108 46 to to IN cord-292559-b21j9sf3 108 47 environmental environmental JJ cord-292559-b21j9sf3 108 48 toxins toxin NNS cord-292559-b21j9sf3 108 49 [ [ -LRB- cord-292559-b21j9sf3 108 50 9 9 CD cord-292559-b21j9sf3 108 51 ] ] -RRB- cord-292559-b21j9sf3 108 52 . . . cord-292559-b21j9sf3 109 1 Youth youth NN cord-292559-b21j9sf3 109 2 who who WP cord-292559-b21j9sf3 109 3 initially initially RB cord-292559-b21j9sf3 109 4 provided provide VBD cord-292559-b21j9sf3 109 5 saliva saliva NN cord-292559-b21j9sf3 109 6 for for IN cord-292559-b21j9sf3 109 7 DNA dna NN cord-292559-b21j9sf3 109 8 assessment assessment NN cord-292559-b21j9sf3 109 9 are be VBP cord-292559-b21j9sf3 109 10 asked ask VBN cord-292559-b21j9sf3 109 11 to to TO cord-292559-b21j9sf3 109 12 provide provide VB cord-292559-b21j9sf3 109 13 blood blood NN cord-292559-b21j9sf3 109 14 in in IN cord-292559-b21j9sf3 109 15 later later JJ cord-292559-b21j9sf3 109 16 years year NNS cord-292559-b21j9sf3 109 17 as as IN cord-292559-b21j9sf3 109 18 they -PRON- PRP cord-292559-b21j9sf3 109 19 become become VBP cord-292559-b21j9sf3 109 20 more more RBR cord-292559-b21j9sf3 109 21 comfortable comfortable JJ cord-292559-b21j9sf3 109 22 with with IN cord-292559-b21j9sf3 109 23 blood blood NN cord-292559-b21j9sf3 109 24 draws draw NNS cord-292559-b21j9sf3 109 25 . . . cord-292559-b21j9sf3 110 1 Neurocognition Neurocognition NNP cord-292559-b21j9sf3 110 2 . . . cord-292559-b21j9sf3 111 1 For for IN cord-292559-b21j9sf3 111 2 an an DT cord-292559-b21j9sf3 111 3 overview overview NN cord-292559-b21j9sf3 111 4 of of IN cord-292559-b21j9sf3 111 5 all all DT cord-292559-b21j9sf3 111 6 measures measure NNS cord-292559-b21j9sf3 111 7 that that WDT cord-292559-b21j9sf3 111 8 started start VBD cord-292559-b21j9sf3 111 9 at at IN cord-292559-b21j9sf3 111 10 baseline baseline NN cord-292559-b21j9sf3 111 11 and and CC cord-292559-b21j9sf3 111 12 year year NN cord-292559-b21j9sf3 111 13 1 1 CD cord-292559-b21j9sf3 111 14 , , , cord-292559-b21j9sf3 111 15 please please UH cord-292559-b21j9sf3 111 16 see see VB cord-292559-b21j9sf3 111 17 ref ref NN cord-292559-b21j9sf3 111 18 . . . cord-292559-b21j9sf3 112 1 [ [ -LRB- cord-292559-b21j9sf3 112 2 8 8 CD cord-292559-b21j9sf3 112 3 ] ] -RRB- cord-292559-b21j9sf3 112 4 . . . cord-292559-b21j9sf3 113 1 The the DT cord-292559-b21j9sf3 113 2 base base NN cord-292559-b21j9sf3 113 3 of of IN cord-292559-b21j9sf3 113 4 the the DT cord-292559-b21j9sf3 113 5 neurocognitive neurocognitive JJ cord-292559-b21j9sf3 113 6 assessment assessment NN cord-292559-b21j9sf3 113 7 for for IN cord-292559-b21j9sf3 113 8 ABCD ABCD NNP cord-292559-b21j9sf3 113 9 Study Study NNP cord-292559-b21j9sf3 113 10 is be VBZ cord-292559-b21j9sf3 113 11 the the DT cord-292559-b21j9sf3 113 12 NIH NIH NNP cord-292559-b21j9sf3 113 13 Toolbox Toolbox NNP cord-292559-b21j9sf3 113 14 [ [ -LRB- cord-292559-b21j9sf3 113 15 26 26 CD cord-292559-b21j9sf3 113 16 , , , cord-292559-b21j9sf3 113 17 27 27 CD cord-292559-b21j9sf3 113 18 ] ] -RRB- cord-292559-b21j9sf3 113 19 , , , cord-292559-b21j9sf3 113 20 with with IN cord-292559-b21j9sf3 113 21 the the DT cord-292559-b21j9sf3 113 22 complete complete JJ cord-292559-b21j9sf3 113 23 cognitive cognitive JJ cord-292559-b21j9sf3 113 24 Toolbox Toolbox NNP cord-292559-b21j9sf3 113 25 administered administer VBN cord-292559-b21j9sf3 113 26 at at IN cord-292559-b21j9sf3 113 27 baseline baseline NN cord-292559-b21j9sf3 113 28 , , , cord-292559-b21j9sf3 113 29 and and CC cord-292559-b21j9sf3 113 30 the the DT cord-292559-b21j9sf3 113 31 majority majority NN cord-292559-b21j9sf3 113 32 of of IN cord-292559-b21j9sf3 113 33 tasks task NNS cord-292559-b21j9sf3 113 34 administered administer VBD cord-292559-b21j9sf3 113 35 every every DT cord-292559-b21j9sf3 113 36 2 2 CD cord-292559-b21j9sf3 113 37 years year NNS cord-292559-b21j9sf3 113 38 . . . cord-292559-b21j9sf3 114 1 The the DT cord-292559-b21j9sf3 114 2 Toolbox Toolbox NNP cord-292559-b21j9sf3 114 3 measures measure NNS cord-292559-b21j9sf3 114 4 were be VBD cord-292559-b21j9sf3 114 5 complemented complement VBN cord-292559-b21j9sf3 114 6 at at IN cord-292559-b21j9sf3 114 7 baseline baseline NN cord-292559-b21j9sf3 114 8 by by IN cord-292559-b21j9sf3 114 9 additional additional JJ cord-292559-b21j9sf3 114 10 assessments assessment NNS cord-292559-b21j9sf3 114 11 of of IN cord-292559-b21j9sf3 114 12 verbal verbal JJ cord-292559-b21j9sf3 114 13 learning learning NN cord-292559-b21j9sf3 114 14 , , , cord-292559-b21j9sf3 114 15 matrix matrix NN cord-292559-b21j9sf3 114 16 reasoning reasoning NN cord-292559-b21j9sf3 114 17 , , , cord-292559-b21j9sf3 114 18 spatial spatial JJ cord-292559-b21j9sf3 114 19 processing processing NN cord-292559-b21j9sf3 114 20 , , , cord-292559-b21j9sf3 114 21 and and CC cord-292559-b21j9sf3 114 22 delay delay VB cord-292559-b21j9sf3 114 23 discounting discounting NN cord-292559-b21j9sf3 114 24 , , , cord-292559-b21j9sf3 114 25 with with IN cord-292559-b21j9sf3 114 26 all all DT cord-292559-b21j9sf3 114 27 of of IN cord-292559-b21j9sf3 114 28 these these DT cord-292559-b21j9sf3 114 29 measures measure NNS cord-292559-b21j9sf3 114 30 other other JJ cord-292559-b21j9sf3 114 31 than than IN cord-292559-b21j9sf3 114 32 matrix matrix NN cord-292559-b21j9sf3 114 33 reasoning reasoning NN cord-292559-b21j9sf3 114 34 repeated repeat VBD cord-292559-b21j9sf3 114 35 approximately approximately RB cord-292559-b21j9sf3 114 36 for for IN cord-292559-b21j9sf3 114 37 every every DT cord-292559-b21j9sf3 114 38 2 2 CD cord-292559-b21j9sf3 114 39 years year NNS cord-292559-b21j9sf3 114 40 [ [ -LRB- cord-292559-b21j9sf3 114 41 8 8 CD cord-292559-b21j9sf3 114 42 ] ] -RRB- cord-292559-b21j9sf3 114 43 . . . cord-292559-b21j9sf3 115 1 Additional additional JJ cord-292559-b21j9sf3 115 2 cognitive cognitive JJ cord-292559-b21j9sf3 115 3 measures measure NNS cord-292559-b21j9sf3 115 4 are be VBP cord-292559-b21j9sf3 115 5 administered administer VBN cord-292559-b21j9sf3 115 6 in in IN cord-292559-b21j9sf3 115 7 alternating alternate VBG cord-292559-b21j9sf3 115 8 years year NNS cord-292559-b21j9sf3 115 9 , , , cord-292559-b21j9sf3 115 10 including include VBG cord-292559-b21j9sf3 115 11 those those DT cord-292559-b21j9sf3 115 12 that that WDT cord-292559-b21j9sf3 115 13 focus focus VBP cord-292559-b21j9sf3 115 14 on on IN cord-292559-b21j9sf3 115 15 more more JJR cord-292559-b21j9sf3 115 16 " " `` cord-292559-b21j9sf3 115 17 hot hot JJ cord-292559-b21j9sf3 115 18 " " '' cord-292559-b21j9sf3 115 19 aspects aspect NNS cord-292559-b21j9sf3 115 20 of of IN cord-292559-b21j9sf3 115 21 cognition cognition NN cord-292559-b21j9sf3 115 22 , , , cord-292559-b21j9sf3 115 23 including include VBG cord-292559-b21j9sf3 115 24 an an DT cord-292559-b21j9sf3 115 25 emotional emotional JJ cord-292559-b21j9sf3 115 26 Stroop Stroop NNP cord-292559-b21j9sf3 115 27 task task NN cord-292559-b21j9sf3 115 28 , , , cord-292559-b21j9sf3 115 29 a a DT cord-292559-b21j9sf3 115 30 monetary monetary JJ cord-292559-b21j9sf3 115 31 decision decision NN cord-292559-b21j9sf3 115 32 - - HYPH cord-292559-b21j9sf3 115 33 making make VBG cord-292559-b21j9sf3 115 34 task task NN cord-292559-b21j9sf3 115 35 , , , cord-292559-b21j9sf3 115 36 and and CC cord-292559-b21j9sf3 115 37 a a DT cord-292559-b21j9sf3 115 38 social social JJ cord-292559-b21j9sf3 115 39 influence influence NN cord-292559-b21j9sf3 115 40 task task NN cord-292559-b21j9sf3 115 41 . . . cord-292559-b21j9sf3 116 1 Assessments assessment NNS cord-292559-b21j9sf3 116 2 of of IN cord-292559-b21j9sf3 116 3 math math NN cord-292559-b21j9sf3 116 4 ability ability NN cord-292559-b21j9sf3 116 5 were be VBD cord-292559-b21j9sf3 116 6 introduced introduce VBN cord-292559-b21j9sf3 116 7 in in IN cord-292559-b21j9sf3 116 8 year year NN cord-292559-b21j9sf3 116 9 3 3 CD cord-292559-b21j9sf3 116 10 ( ( -LRB- cord-292559-b21j9sf3 116 11 youth youth NN cord-292559-b21j9sf3 116 12 = = SYM cord-292559-b21j9sf3 116 13 12 12 CD cord-292559-b21j9sf3 116 14 - - HYPH cord-292559-b21j9sf3 116 15 13-years 13-years CD cord-292559-b21j9sf3 116 16 - - HYPH cord-292559-b21j9sf3 116 17 old old JJ cord-292559-b21j9sf3 116 18 ) ) -RRB- cord-292559-b21j9sf3 116 19 . . . cord-292559-b21j9sf3 117 1 These these DT cord-292559-b21j9sf3 117 2 assessments assessment NNS cord-292559-b21j9sf3 117 3 are be VBP cord-292559-b21j9sf3 117 4 contextualized contextualize VBN cord-292559-b21j9sf3 117 5 by by IN cord-292559-b21j9sf3 117 6 vision vision NN cord-292559-b21j9sf3 117 7 assessments assessment NNS cord-292559-b21j9sf3 117 8 for for IN cord-292559-b21j9sf3 117 9 every every DT cord-292559-b21j9sf3 117 10 2 2 CD cord-292559-b21j9sf3 117 11 years year NNS cord-292559-b21j9sf3 117 12 , , , cord-292559-b21j9sf3 117 13 and and CC cord-292559-b21j9sf3 117 14 a a DT cord-292559-b21j9sf3 117 15 measure measure NN cord-292559-b21j9sf3 117 16 of of IN cord-292559-b21j9sf3 117 17 hand hand NN cord-292559-b21j9sf3 117 18 dominance dominance NN cord-292559-b21j9sf3 117 19 . . . cord-292559-b21j9sf3 118 1 Gender gender NN cord-292559-b21j9sf3 118 2 identity identity NN cord-292559-b21j9sf3 118 3 and and CC cord-292559-b21j9sf3 118 4 sexual sexual JJ cord-292559-b21j9sf3 118 5 health health NN cord-292559-b21j9sf3 118 6 . . . cord-292559-b21j9sf3 119 1 The the DT cord-292559-b21j9sf3 119 2 goal goal NN cord-292559-b21j9sf3 119 3 of of IN cord-292559-b21j9sf3 119 4 the the DT cord-292559-b21j9sf3 119 5 gender gender NN cord-292559-b21j9sf3 119 6 identity identity NN cord-292559-b21j9sf3 119 7 and and CC cord-292559-b21j9sf3 119 8 sexual sexual JJ cord-292559-b21j9sf3 119 9 health health NN cord-292559-b21j9sf3 119 10 assessments assessment NNS cord-292559-b21j9sf3 119 11 are be VBP cord-292559-b21j9sf3 119 12 to to TO cord-292559-b21j9sf3 119 13 provide provide VB cord-292559-b21j9sf3 119 14 developmentally developmentally RB cord-292559-b21j9sf3 119 15 appropriate appropriate JJ cord-292559-b21j9sf3 119 16 assessments assessment NNS cord-292559-b21j9sf3 119 17 of of IN cord-292559-b21j9sf3 119 18 gender gender NN cord-292559-b21j9sf3 119 19 identity identity NN cord-292559-b21j9sf3 119 20 and and CC cord-292559-b21j9sf3 119 21 expression expression NN cord-292559-b21j9sf3 119 22 , , , cord-292559-b21j9sf3 119 23 as as RB cord-292559-b21j9sf3 119 24 well well RB cord-292559-b21j9sf3 119 25 as as IN cord-292559-b21j9sf3 119 26 sexual sexual JJ cord-292559-b21j9sf3 119 27 identity identity NN cord-292559-b21j9sf3 119 28 and and CC cord-292559-b21j9sf3 119 29 communication communication NN cord-292559-b21j9sf3 119 30 about about IN cord-292559-b21j9sf3 119 31 sexual sexual JJ cord-292559-b21j9sf3 119 32 health health NN cord-292559-b21j9sf3 119 33 . . . cord-292559-b21j9sf3 120 1 Both both DT cord-292559-b21j9sf3 120 2 youth youth NN cord-292559-b21j9sf3 120 3 and and CC cord-292559-b21j9sf3 120 4 parent parent NN cord-292559-b21j9sf3 120 5 complete complete VB cord-292559-b21j9sf3 120 6 a a DT cord-292559-b21j9sf3 120 7 questionnaire questionnaire NN cord-292559-b21j9sf3 120 8 about about IN cord-292559-b21j9sf3 120 9 gender gender NN cord-292559-b21j9sf3 120 10 identity identity NN cord-292559-b21j9sf3 120 11 , , , cord-292559-b21j9sf3 120 12 including include VBG cord-292559-b21j9sf3 120 13 questions question NNS cord-292559-b21j9sf3 120 14 on on IN cord-292559-b21j9sf3 120 15 gender gender NN cord-292559-b21j9sf3 120 16 identity identity NN cord-292559-b21j9sf3 120 17 and and CC cord-292559-b21j9sf3 120 18 gender gender NN cord-292559-b21j9sf3 120 19 expression expression NN cord-292559-b21j9sf3 120 20 , , , cord-292559-b21j9sf3 120 21 with with IN cord-292559-b21j9sf3 120 22 the the DT cord-292559-b21j9sf3 120 23 youth youth NN cord-292559-b21j9sf3 120 24 also also RB cord-292559-b21j9sf3 120 25 reporting report VBG cord-292559-b21j9sf3 120 26 on on IN cord-292559-b21j9sf3 120 27 dimensional dimensional JJ cord-292559-b21j9sf3 120 28 assessments assessment NNS cord-292559-b21j9sf3 120 29 of of IN cord-292559-b21j9sf3 120 30 gender gender NN cord-292559-b21j9sf3 120 31 identity identity NN cord-292559-b21j9sf3 120 32 . . . cord-292559-b21j9sf3 121 1 For for IN cord-292559-b21j9sf3 121 2 an an DT cord-292559-b21j9sf3 121 3 overview overview NN cord-292559-b21j9sf3 121 4 of of IN cord-292559-b21j9sf3 121 5 all all DT cord-292559-b21j9sf3 121 6 measures measure NNS cord-292559-b21j9sf3 121 7 that that WDT cord-292559-b21j9sf3 121 8 started start VBD cord-292559-b21j9sf3 121 9 at at IN cord-292559-b21j9sf3 121 10 baseline baseline NN cord-292559-b21j9sf3 121 11 and and CC cord-292559-b21j9sf3 121 12 year year NN cord-292559-b21j9sf3 121 13 1 1 CD cord-292559-b21j9sf3 121 14 , , , cord-292559-b21j9sf3 121 15 please please UH cord-292559-b21j9sf3 121 16 see see VB cord-292559-b21j9sf3 121 17 ref ref NN cord-292559-b21j9sf3 121 18 . . . cord-292559-b21j9sf3 122 1 [ [ -LRB- cord-292559-b21j9sf3 122 2 18 18 CD cord-292559-b21j9sf3 122 3 ] ] -RRB- cord-292559-b21j9sf3 122 4 . . . cord-292559-b21j9sf3 123 1 The the DT cord-292559-b21j9sf3 123 2 assessments assessment NNS cord-292559-b21j9sf3 123 3 of of IN cord-292559-b21j9sf3 123 4 culture culture NN cord-292559-b21j9sf3 123 5 and and CC cord-292559-b21j9sf3 123 6 environment environment NN cord-292559-b21j9sf3 123 7 include include VBP cord-292559-b21j9sf3 123 8 both both DT cord-292559-b21j9sf3 123 9 youth youth NN cord-292559-b21j9sf3 123 10 and and CC cord-292559-b21j9sf3 123 11 parent parent NN cord-292559-b21j9sf3 123 12 / / SYM cord-292559-b21j9sf3 123 13 caregiver caregiver NN cord-292559-b21j9sf3 123 14 's 's POS cord-292559-b21j9sf3 123 15 perspectives perspective NNS cord-292559-b21j9sf3 123 16 on on IN cord-292559-b21j9sf3 123 17 family family NN cord-292559-b21j9sf3 123 18 relationships relationship NNS cord-292559-b21j9sf3 123 19 , , , cord-292559-b21j9sf3 123 20 conflict conflict NN cord-292559-b21j9sf3 123 21 , , , cord-292559-b21j9sf3 123 22 parent parent NN cord-292559-b21j9sf3 123 23 acceptance acceptance NN cord-292559-b21j9sf3 123 24 and and CC cord-292559-b21j9sf3 123 25 rules rule NNS cord-292559-b21j9sf3 123 26 , , , cord-292559-b21j9sf3 123 27 familial familial JJ cord-292559-b21j9sf3 123 28 cultural cultural JJ cord-292559-b21j9sf3 123 29 experiences experience NNS cord-292559-b21j9sf3 123 30 and and CC cord-292559-b21j9sf3 123 31 values value NNS cord-292559-b21j9sf3 123 32 , , , cord-292559-b21j9sf3 123 33 pet pet JJ cord-292559-b21j9sf3 123 34 ownership ownership NN cord-292559-b21j9sf3 123 35 , , , cord-292559-b21j9sf3 123 36 and and CC cord-292559-b21j9sf3 123 37 other other JJ cord-292559-b21j9sf3 123 38 aspects aspect NNS cord-292559-b21j9sf3 123 39 of of IN cord-292559-b21j9sf3 123 40 the the DT cord-292559-b21j9sf3 123 41 home home NN cord-292559-b21j9sf3 123 42 environment environment NN cord-292559-b21j9sf3 123 43 such such JJ cord-292559-b21j9sf3 123 44 as as IN cord-292559-b21j9sf3 123 45 the the DT cord-292559-b21j9sf3 123 46 nature nature NN cord-292559-b21j9sf3 123 47 of of IN cord-292559-b21j9sf3 123 48 home home NN cord-292559-b21j9sf3 123 49 spaces space NNS cord-292559-b21j9sf3 123 50 and and CC cord-292559-b21j9sf3 123 51 parent parent NN cord-292559-b21j9sf3 123 52 - - HYPH cord-292559-b21j9sf3 123 53 youth youth NN cord-292559-b21j9sf3 123 54 interactions interaction NNS cord-292559-b21j9sf3 123 55 in in IN cord-292559-b21j9sf3 123 56 the the DT cord-292559-b21j9sf3 123 57 home home NN cord-292559-b21j9sf3 123 58 around around IN cord-292559-b21j9sf3 123 59 cognitive cognitive JJ cord-292559-b21j9sf3 123 60 and and CC cord-292559-b21j9sf3 123 61 emotional emotional JJ cord-292559-b21j9sf3 123 62 behaviors behavior NNS cord-292559-b21j9sf3 123 63 . . . cord-292559-b21j9sf3 124 1 This this DT cord-292559-b21j9sf3 124 2 domain domain NN cord-292559-b21j9sf3 124 3 also also RB cord-292559-b21j9sf3 124 4 assesses assess VBZ cord-292559-b21j9sf3 124 5 characteristics characteristic NNS cord-292559-b21j9sf3 124 6 of of IN cord-292559-b21j9sf3 124 7 the the DT cord-292559-b21j9sf3 124 8 neighborhood neighborhood NN cord-292559-b21j9sf3 124 9 from from IN cord-292559-b21j9sf3 124 10 the the DT cord-292559-b21j9sf3 124 11 perspective perspective NN cord-292559-b21j9sf3 124 12 of of IN cord-292559-b21j9sf3 124 13 the the DT cord-292559-b21j9sf3 124 14 youth youth NN cord-292559-b21j9sf3 124 15 and/or and/or CC cord-292559-b21j9sf3 124 16 parent parent NN cord-292559-b21j9sf3 124 17 / / SYM cord-292559-b21j9sf3 124 18 caregiver caregiver NN cord-292559-b21j9sf3 124 19 , , , cord-292559-b21j9sf3 124 20 including include VBG cord-292559-b21j9sf3 124 21 perceptions perception NNS cord-292559-b21j9sf3 124 22 of of IN cord-292559-b21j9sf3 124 23 crime crime NN cord-292559-b21j9sf3 124 24 and and CC cord-292559-b21j9sf3 124 25 safety safety NN cord-292559-b21j9sf3 124 26 , , , cord-292559-b21j9sf3 124 27 community community NN cord-292559-b21j9sf3 124 28 cohesion cohesion NN cord-292559-b21j9sf3 124 29 , , , cord-292559-b21j9sf3 124 30 and and CC cord-292559-b21j9sf3 124 31 school school NN cord-292559-b21j9sf3 124 32 attributes attribute NNS cord-292559-b21j9sf3 124 33 . . . cord-292559-b21j9sf3 125 1 Data datum NNS cord-292559-b21j9sf3 125 2 releases release NNS cord-292559-b21j9sf3 125 3 also also RB cord-292559-b21j9sf3 125 4 include include VBP cord-292559-b21j9sf3 125 5 several several JJ cord-292559-b21j9sf3 125 6 variables variable NNS cord-292559-b21j9sf3 125 7 geocoded geocode VBN cord-292559-b21j9sf3 125 8 based base VBN cord-292559-b21j9sf3 125 9 on on IN cord-292559-b21j9sf3 125 10 the the DT cord-292559-b21j9sf3 125 11 participant participant NN cord-292559-b21j9sf3 125 12 's 's POS cord-292559-b21j9sf3 125 13 address address NN cord-292559-b21j9sf3 125 14 and and CC cord-292559-b21j9sf3 125 15 derived derive VBN cord-292559-b21j9sf3 125 16 from from IN cord-292559-b21j9sf3 125 17 publicly publicly RB cord-292559-b21j9sf3 125 18 available available JJ cord-292559-b21j9sf3 125 19 data datum NNS cord-292559-b21j9sf3 125 20 such such JJ cord-292559-b21j9sf3 125 21 as as IN cord-292559-b21j9sf3 125 22 the the DT cord-292559-b21j9sf3 125 23 American American NNP cord-292559-b21j9sf3 125 24 Community Community NNP cord-292559-b21j9sf3 125 25 Survey Survey NNP cord-292559-b21j9sf3 125 26 's 's POS cord-292559-b21j9sf3 125 27 metrics metric NNS cord-292559-b21j9sf3 125 28 of of IN cord-292559-b21j9sf3 125 29 socioeconomic socioeconomic JJ cord-292559-b21j9sf3 125 30 characteristics characteristic NNS cord-292559-b21j9sf3 125 31 . . . cord-292559-b21j9sf3 126 1 These these DT cord-292559-b21j9sf3 126 2 variables variable NNS cord-292559-b21j9sf3 126 3 include include VBP cord-292559-b21j9sf3 126 4 population population NN cord-292559-b21j9sf3 126 5 density density NN cord-292559-b21j9sf3 126 6 , , , cord-292559-b21j9sf3 126 7 neighborhood neighborhood NN cord-292559-b21j9sf3 126 8 walkability walkability NN cord-292559-b21j9sf3 126 9 , , , cord-292559-b21j9sf3 126 10 county county NN cord-292559-b21j9sf3 126 11 - - HYPH cord-292559-b21j9sf3 126 12 level level NN cord-292559-b21j9sf3 126 13 crime crime NN cord-292559-b21j9sf3 126 14 exposure exposure NN cord-292559-b21j9sf3 126 15 information information NN cord-292559-b21j9sf3 126 16 , , , cord-292559-b21j9sf3 126 17 census census NN cord-292559-b21j9sf3 126 18 - - HYPH cord-292559-b21j9sf3 126 19 tract tract NN cord-292559-b21j9sf3 126 20 level level NN cord-292559-b21j9sf3 126 21 estimates estimate NNS cord-292559-b21j9sf3 126 22 of of IN cord-292559-b21j9sf3 126 23 area area NN cord-292559-b21j9sf3 126 24 deprivation deprivation NN cord-292559-b21j9sf3 126 25 indices index NNS cord-292559-b21j9sf3 126 26 , , , cord-292559-b21j9sf3 126 27 air air NN cord-292559-b21j9sf3 126 28 pollution pollution NN cord-292559-b21j9sf3 126 29 exposure exposure NN cord-292559-b21j9sf3 126 30 ( ( -LRB- cord-292559-b21j9sf3 126 31 estimated estimate VBN cord-292559-b21j9sf3 126 32 with with IN cord-292559-b21j9sf3 126 33 a a DT cord-292559-b21j9sf3 126 34 resolution resolution NN cord-292559-b21j9sf3 126 35 of of IN cord-292559-b21j9sf3 126 36 100 100 CD cord-292559-b21j9sf3 126 37 km km NNS cord-292559-b21j9sf3 126 38 2 2 CD cord-292559-b21j9sf3 126 39 of of IN cord-292559-b21j9sf3 126 40 address address NN cord-292559-b21j9sf3 126 41 ) ) -RRB- cord-292559-b21j9sf3 126 42 , , , cord-292559-b21j9sf3 126 43 and and CC cord-292559-b21j9sf3 126 44 lead lead VB cord-292559-b21j9sf3 126 45 exposure exposure NN cord-292559-b21j9sf3 126 46 risk risk NN cord-292559-b21j9sf3 126 47 . . . cord-292559-b21j9sf3 127 1 Brain brain NN cord-292559-b21j9sf3 127 2 imaging imaging NN cord-292559-b21j9sf3 127 3 . . . cord-292559-b21j9sf3 128 1 For for IN cord-292559-b21j9sf3 128 2 an an DT cord-292559-b21j9sf3 128 3 overview overview NN cord-292559-b21j9sf3 128 4 of of IN cord-292559-b21j9sf3 128 5 all all DT cord-292559-b21j9sf3 128 6 measures measure NNS cord-292559-b21j9sf3 128 7 that that WDT cord-292559-b21j9sf3 128 8 started start VBD cord-292559-b21j9sf3 128 9 at at IN cord-292559-b21j9sf3 128 10 baseline baseline NN cord-292559-b21j9sf3 128 11 , , , cord-292559-b21j9sf3 128 12 see see VB cord-292559-b21j9sf3 128 13 ref ref NN cord-292559-b21j9sf3 128 14 . . . cord-292559-b21j9sf3 129 1 [ [ -LRB- cord-292559-b21j9sf3 129 2 17 17 CD cord-292559-b21j9sf3 129 3 ] ] -RRB- cord-292559-b21j9sf3 129 4 and and CC cord-292559-b21j9sf3 129 5 for for IN cord-292559-b21j9sf3 129 6 processing processing NN cord-292559-b21j9sf3 129 7 approaches approach NNS cord-292559-b21j9sf3 129 8 and and CC cord-292559-b21j9sf3 129 9 information information NN cord-292559-b21j9sf3 129 10 about about IN cord-292559-b21j9sf3 129 11 released release VBN cord-292559-b21j9sf3 129 12 data datum NNS cord-292559-b21j9sf3 129 13 , , , cord-292559-b21j9sf3 129 14 see see VB cord-292559-b21j9sf3 129 15 ref ref NN cord-292559-b21j9sf3 129 16 . . . cord-292559-b21j9sf3 130 1 [ [ -LRB- cord-292559-b21j9sf3 130 2 28 28 CD cord-292559-b21j9sf3 130 3 ] ] -RRB- cord-292559-b21j9sf3 130 4 . . . cord-292559-b21j9sf3 131 1 Youth youth NN cord-292559-b21j9sf3 131 2 participate participate VBP cord-292559-b21j9sf3 131 3 in in IN cord-292559-b21j9sf3 131 4 a a DT cord-292559-b21j9sf3 131 5 magnetic magnetic JJ cord-292559-b21j9sf3 131 6 resonance resonance NN cord-292559-b21j9sf3 131 7 imaging imaging NN cord-292559-b21j9sf3 131 8 ( ( -LRB- cord-292559-b21j9sf3 131 9 MRI MRI NNP cord-292559-b21j9sf3 131 10 ) ) -RRB- cord-292559-b21j9sf3 131 11 session session NN cord-292559-b21j9sf3 131 12 for for IN cord-292559-b21j9sf3 131 13 every every DT cord-292559-b21j9sf3 131 14 2 2 CD cord-292559-b21j9sf3 131 15 years year NNS cord-292559-b21j9sf3 131 16 . . . cord-292559-b21j9sf3 132 1 This this DT cord-292559-b21j9sf3 132 2 MRI MRI NNP cord-292559-b21j9sf3 132 3 assessment assessment NN cord-292559-b21j9sf3 132 4 includes include VBZ cord-292559-b21j9sf3 132 5 measures measure NNS cord-292559-b21j9sf3 132 6 of of IN cord-292559-b21j9sf3 132 7 brain brain NN cord-292559-b21j9sf3 132 8 structure structure NN cord-292559-b21j9sf3 132 9 , , , cord-292559-b21j9sf3 132 10 with with IN cord-292559-b21j9sf3 132 11 both both CC cord-292559-b21j9sf3 132 12 T1 T1 NNP cord-292559-b21j9sf3 132 13 and and CC cord-292559-b21j9sf3 132 14 T2 T2 NNP cord-292559-b21j9sf3 132 15 weighted weighted JJ cord-292559-b21j9sf3 132 16 imaging imaging NN cord-292559-b21j9sf3 132 17 and and CC cord-292559-b21j9sf3 132 18 diffusion diffusion NN cord-292559-b21j9sf3 132 19 imaging imaging NN cord-292559-b21j9sf3 132 20 for for IN cord-292559-b21j9sf3 132 21 assessment assessment NN cord-292559-b21j9sf3 132 22 of of IN cord-292559-b21j9sf3 132 23 white white JJ cord-292559-b21j9sf3 132 24 mater mater NN cord-292559-b21j9sf3 132 25 integrity integrity NN cord-292559-b21j9sf3 132 26 . . . cord-292559-b21j9sf3 133 1 The the DT cord-292559-b21j9sf3 133 2 MRI MRI NNP cord-292559-b21j9sf3 133 3 assessment assessment NN cord-292559-b21j9sf3 133 4 also also RB cord-292559-b21j9sf3 133 5 includes include VBZ cord-292559-b21j9sf3 133 6 20 20 CD cord-292559-b21j9sf3 133 7 min min NN cord-292559-b21j9sf3 133 8 of of IN cord-292559-b21j9sf3 133 9 resting rest VBG cord-292559-b21j9sf3 133 10 state state NN cord-292559-b21j9sf3 133 11 functional functional JJ cord-292559-b21j9sf3 133 12 connectivity connectivity NN cord-292559-b21j9sf3 133 13 data datum NNS cord-292559-b21j9sf3 133 14 and and CC cord-292559-b21j9sf3 133 15 functional functional JJ cord-292559-b21j9sf3 133 16 MRI mri NN cord-292559-b21j9sf3 133 17 during during IN cord-292559-b21j9sf3 133 18 three three CD cord-292559-b21j9sf3 133 19 different different JJ cord-292559-b21j9sf3 133 20 task task NN cord-292559-b21j9sf3 133 21 domains domain NNS cord-292559-b21j9sf3 133 22 . . . cord-292559-b21j9sf3 134 1 These these DT cord-292559-b21j9sf3 134 2 domains domain NNS cord-292559-b21j9sf3 134 3 were be VBD cord-292559-b21j9sf3 134 4 designed design VBN cord-292559-b21j9sf3 134 5 to to TO cord-292559-b21j9sf3 134 6 capture capture VB cord-292559-b21j9sf3 134 7 brain brain NN cord-292559-b21j9sf3 134 8 activity activity NN cord-292559-b21j9sf3 134 9 during during IN cord-292559-b21j9sf3 134 10 numerous numerous JJ cord-292559-b21j9sf3 134 11 aspects aspect NNS cord-292559-b21j9sf3 134 12 of of IN cord-292559-b21j9sf3 134 13 cognition cognition NN cord-292559-b21j9sf3 134 14 and and CC cord-292559-b21j9sf3 134 15 emotion emotion NN cord-292559-b21j9sf3 134 16 function function NN cord-292559-b21j9sf3 134 17 in in IN cord-292559-b21j9sf3 134 18 as as RB cord-292559-b21j9sf3 134 19 short short JJ cord-292559-b21j9sf3 134 20 a a DT cord-292559-b21j9sf3 134 21 time time NN cord-292559-b21j9sf3 134 22 as as IN cord-292559-b21j9sf3 134 23 possible possible JJ cord-292559-b21j9sf3 134 24 , , , cord-292559-b21j9sf3 134 25 including include VBG cord-292559-b21j9sf3 134 26 working work VBG cord-292559-b21j9sf3 134 27 memory memory NN cord-292559-b21j9sf3 134 28 , , , cord-292559-b21j9sf3 134 29 response response NN cord-292559-b21j9sf3 134 30 inhibition inhibition NN cord-292559-b21j9sf3 134 31 , , , cord-292559-b21j9sf3 134 32 anticipation anticipation NN cord-292559-b21j9sf3 134 33 and and CC cord-292559-b21j9sf3 134 34 receipt receipt NN cord-292559-b21j9sf3 134 35 of of IN cord-292559-b21j9sf3 134 36 rewards reward NNS cord-292559-b21j9sf3 134 37 and and CC cord-292559-b21j9sf3 134 38 losses loss NNS cord-292559-b21j9sf3 134 39 , , , cord-292559-b21j9sf3 134 40 face face NN cord-292559-b21j9sf3 134 41 processing processing NN cord-292559-b21j9sf3 134 42 ( ( -LRB- cord-292559-b21j9sf3 134 43 both both DT cord-292559-b21j9sf3 134 44 neutral neutral JJ cord-292559-b21j9sf3 134 45 and and CC cord-292559-b21j9sf3 134 46 emotional emotional JJ cord-292559-b21j9sf3 134 47 ) ) -RRB- cord-292559-b21j9sf3 134 48 , , , cord-292559-b21j9sf3 134 49 and and CC cord-292559-b21j9sf3 134 50 subsequent subsequent JJ cord-292559-b21j9sf3 134 51 memory memory NN cord-292559-b21j9sf3 134 52 . . . cord-292559-b21j9sf3 135 1 Processed process VBN cord-292559-b21j9sf3 135 2 data datum NNS cord-292559-b21j9sf3 135 3 from from IN cord-292559-b21j9sf3 135 4 each each DT cord-292559-b21j9sf3 135 5 of of IN cord-292559-b21j9sf3 135 6 these these DT cord-292559-b21j9sf3 135 7 domains domain NNS cord-292559-b21j9sf3 135 8 is be VBZ cord-292559-b21j9sf3 135 9 released release VBN cord-292559-b21j9sf3 135 10 in in IN cord-292559-b21j9sf3 135 11 tabular tabular JJ cord-292559-b21j9sf3 135 12 format format NN cord-292559-b21j9sf3 135 13 as as IN cord-292559-b21j9sf3 135 14 part part NN cord-292559-b21j9sf3 135 15 of of IN cord-292559-b21j9sf3 135 16 the the DT cord-292559-b21j9sf3 135 17 ABCD ABCD NNP cord-292559-b21j9sf3 135 18 Annual Annual NNP cord-292559-b21j9sf3 135 19 Releases Releases NNPS cord-292559-b21j9sf3 135 20 using use VBG cord-292559-b21j9sf3 135 21 a a DT cord-292559-b21j9sf3 135 22 variety variety NN cord-292559-b21j9sf3 135 23 of of IN cord-292559-b21j9sf3 135 24 brain brain NN cord-292559-b21j9sf3 135 25 atlases atlas NNS cord-292559-b21j9sf3 135 26 . . . cord-292559-b21j9sf3 136 1 Raw Raw NNP cord-292559-b21j9sf3 136 2 MRI MRI NNP cord-292559-b21j9sf3 136 3 data datum NNS cord-292559-b21j9sf3 136 4 is be VBZ cord-292559-b21j9sf3 136 5 available available JJ cord-292559-b21j9sf3 136 6 through through IN cord-292559-b21j9sf3 136 7 the the DT cord-292559-b21j9sf3 136 8 Fast Fast NNP cord-292559-b21j9sf3 136 9 Track Track NNP cord-292559-b21j9sf3 136 10 release release NN cord-292559-b21j9sf3 136 11 mechanism mechanism NN cord-292559-b21j9sf3 136 12 ( ( -LRB- cord-292559-b21j9sf3 136 13 https://nda https://nda NN cord-292559-b21j9sf3 136 14 . . . cord-292559-b21j9sf3 136 15 nih.gov/abcd/query/abcd-fast-track-data.html nih.gov/abcd/query/abcd-fast-track-data.html NN cord-292559-b21j9sf3 136 16 ) ) -RRB- cord-292559-b21j9sf3 136 17 . . . cord-292559-b21j9sf3 137 1 The the DT cord-292559-b21j9sf3 137 2 ABCD ABCD NNP cord-292559-b21j9sf3 137 3 Study Study NNP cord-292559-b21j9sf3 137 4 was be VBD cord-292559-b21j9sf3 137 5 begun begin VBN cord-292559-b21j9sf3 137 6 in in IN cord-292559-b21j9sf3 137 7 the the DT cord-292559-b21j9sf3 137 8 footsteps footstep NNS cord-292559-b21j9sf3 137 9 of of IN cord-292559-b21j9sf3 137 10 several several JJ cord-292559-b21j9sf3 137 11 other other JJ cord-292559-b21j9sf3 137 12 large large JJ cord-292559-b21j9sf3 137 13 population population NN cord-292559-b21j9sf3 137 14 neuroscience neuroscience NN cord-292559-b21j9sf3 137 15 studies study NNS cord-292559-b21j9sf3 137 16 . . . cord-292559-b21j9sf3 138 1 These these DT cord-292559-b21j9sf3 138 2 studies study NNS cord-292559-b21j9sf3 138 3 include include VBP cord-292559-b21j9sf3 138 4 the the DT cord-292559-b21j9sf3 138 5 Sanguenay Sanguenay NNP cord-292559-b21j9sf3 138 6 Youth Youth NNP cord-292559-b21j9sf3 138 7 Study Study NNP cord-292559-b21j9sf3 138 8 ( ( -LRB- cord-292559-b21j9sf3 138 9 http://saguenay-youth-study.org http://saguenay-youth-study.org NNP cord-292559-b21j9sf3 138 10 ; ; : cord-292559-b21j9sf3 138 11 N n NN cord-292559-b21j9sf3 138 12 = = SYM cord-292559-b21j9sf3 138 13 1029 1029 CD cord-292559-b21j9sf3 138 14 ) ) -RRB- cord-292559-b21j9sf3 138 15 [ [ -LRB- cord-292559-b21j9sf3 138 16 29 29 CD cord-292559-b21j9sf3 138 17 ] ] -RRB- cord-292559-b21j9sf3 138 18 , , , cord-292559-b21j9sf3 138 19 the the DT cord-292559-b21j9sf3 138 20 National National NNP cord-292559-b21j9sf3 138 21 Institutes Institutes NNPS cord-292559-b21j9sf3 138 22 of of IN cord-292559-b21j9sf3 138 23 Health Health NNP cord-292559-b21j9sf3 138 24 Pediatric Pediatric NNP cord-292559-b21j9sf3 138 25 MRI MRI NNP cord-292559-b21j9sf3 138 26 Database database NN cord-292559-b21j9sf3 138 27 ( ( -LRB- cord-292559-b21j9sf3 138 28 N n NN cord-292559-b21j9sf3 138 29 = = SYM cord-292559-b21j9sf3 138 30 550 550 CD cord-292559-b21j9sf3 138 31 ) ) -RRB- cord-292559-b21j9sf3 138 32 [ [ -LRB- cord-292559-b21j9sf3 138 33 30 30 CD cord-292559-b21j9sf3 138 34 ] ] -RRB- cord-292559-b21j9sf3 138 35 , , , cord-292559-b21j9sf3 138 36 IMAGEN IMAGEN NNP cord-292559-b21j9sf3 138 37 ( ( -LRB- cord-292559-b21j9sf3 138 38 N n NN cord-292559-b21j9sf3 138 39 = = SYM cord-292559-b21j9sf3 138 40 2000 2000 CD cord-292559-b21j9sf3 138 41 ) ) -RRB- cord-292559-b21j9sf3 138 42 [ [ -LRB- cord-292559-b21j9sf3 138 43 6 6 CD cord-292559-b21j9sf3 138 44 ] ] -RRB- cord-292559-b21j9sf3 138 45 , , , cord-292559-b21j9sf3 138 46 Pediatric Pediatric NNP cord-292559-b21j9sf3 138 47 Imaging Imaging NNP cord-292559-b21j9sf3 138 48 , , , cord-292559-b21j9sf3 138 49 Neurocognition Neurocognition NNP cord-292559-b21j9sf3 138 50 , , , cord-292559-b21j9sf3 138 51 and and CC cord-292559-b21j9sf3 138 52 Genetics Genetics NNP cord-292559-b21j9sf3 138 53 study study NN cord-292559-b21j9sf3 138 54 ( ( -LRB- cord-292559-b21j9sf3 138 55 PING ping NN cord-292559-b21j9sf3 138 56 ) ) -RRB- cord-292559-b21j9sf3 138 57 ( ( -LRB- cord-292559-b21j9sf3 138 58 N n NN cord-292559-b21j9sf3 138 59 = = SYM cord-292559-b21j9sf3 138 60 1493 1493 CD cord-292559-b21j9sf3 138 61 ) ) -RRB- cord-292559-b21j9sf3 138 62 [ [ -LRB- cord-292559-b21j9sf3 138 63 31 31 CD cord-292559-b21j9sf3 138 64 ] ] -RRB- cord-292559-b21j9sf3 138 65 , , , cord-292559-b21j9sf3 138 66 National National NNP cord-292559-b21j9sf3 138 67 Consortium Consortium NNP cord-292559-b21j9sf3 138 68 on on IN cord-292559-b21j9sf3 138 69 Alcohol Alcohol NNP cord-292559-b21j9sf3 138 70 and and CC cord-292559-b21j9sf3 138 71 NeuroDevelopment NeuroDevelopment NNP cord-292559-b21j9sf3 138 72 in in IN cord-292559-b21j9sf3 138 73 Adolescence Adolescence NNP cord-292559-b21j9sf3 138 74 ( ( -LRB- cord-292559-b21j9sf3 138 75 NCANDA NCANDA NNP cord-292559-b21j9sf3 138 76 ) ) -RRB- cord-292559-b21j9sf3 139 1 ( ( -LRB- cord-292559-b21j9sf3 139 2 N n NN cord-292559-b21j9sf3 139 3 = = SYM cord-292559-b21j9sf3 139 4 831 831 CD cord-292559-b21j9sf3 139 5 ) ) -RRB- cord-292559-b21j9sf3 139 6 [ [ -LRB- cord-292559-b21j9sf3 139 7 4 4 CD cord-292559-b21j9sf3 139 8 ] ] -RRB- cord-292559-b21j9sf3 139 9 , , , cord-292559-b21j9sf3 139 10 Human Human NNP cord-292559-b21j9sf3 139 11 Connectome Connectome NNP cord-292559-b21j9sf3 139 12 Project Project NNP cord-292559-b21j9sf3 139 13 ( ( -LRB- cord-292559-b21j9sf3 139 14 HCP HCP NNP cord-292559-b21j9sf3 139 15 ) ) -RRB- cord-292559-b21j9sf3 140 1 ( ( -LRB- cord-292559-b21j9sf3 140 2 N n NN cord-292559-b21j9sf3 140 3 = = SYM cord-292559-b21j9sf3 140 4 1200 1200 CD cord-292559-b21j9sf3 140 5 ) ) -RRB- cord-292559-b21j9sf3 141 1 [ [ -LRB- cord-292559-b21j9sf3 141 2 32 32 CD cord-292559-b21j9sf3 141 3 , , , cord-292559-b21j9sf3 141 4 33 33 CD cord-292559-b21j9sf3 141 5 ] ] -RRB- cord-292559-b21j9sf3 141 6 , , , cord-292559-b21j9sf3 141 7 and and CC cord-292559-b21j9sf3 141 8 HCP HCP NNP cord-292559-b21j9sf3 141 9 - - HYPH cord-292559-b21j9sf3 141 10 Development Development NNP cord-292559-b21j9sf3 141 11 ( ( -LRB- cord-292559-b21j9sf3 141 12 HCP HCP NNP cord-292559-b21j9sf3 141 13 - - HYPH cord-292559-b21j9sf3 141 14 D D NNP cord-292559-b21j9sf3 141 15 ; ; : cord-292559-b21j9sf3 141 16 N n NN cord-292559-b21j9sf3 141 17 = = SYM cord-292559-b21j9sf3 141 18 1350 1350 CD cord-292559-b21j9sf3 141 19 [ [ -LRB- cord-292559-b21j9sf3 141 20 34 34 CD cord-292559-b21j9sf3 141 21 ] ] -RRB- cord-292559-b21j9sf3 141 22 ) ) -RRB- cord-292559-b21j9sf3 141 23 , , , cord-292559-b21j9sf3 141 24 UK UK NNP cord-292559-b21j9sf3 141 25 Biobank Biobank NNP cord-292559-b21j9sf3 141 26 ( ( -LRB- cord-292559-b21j9sf3 141 27 N n NN cord-292559-b21j9sf3 141 28 = = SYM cord-292559-b21j9sf3 141 29 over over IN cord-292559-b21j9sf3 141 30 500,000 500,000 CD cord-292559-b21j9sf3 141 31 ) ) -RRB- cord-292559-b21j9sf3 142 1 [ [ -LRB- cord-292559-b21j9sf3 142 2 35 35 CD cord-292559-b21j9sf3 142 3 ] ] -RRB- cord-292559-b21j9sf3 142 4 , , , cord-292559-b21j9sf3 142 5 Generation generation NN cord-292559-b21j9sf3 142 6 R r NN cord-292559-b21j9sf3 142 7 ( ( -LRB- cord-292559-b21j9sf3 142 8 N n NN cord-292559-b21j9sf3 142 9 = = SYM cord-292559-b21j9sf3 142 10 9778 9778 CD cord-292559-b21j9sf3 142 11 ) ) -RRB- cord-292559-b21j9sf3 142 12 [ [ -LRB- cord-292559-b21j9sf3 142 13 5 5 CD cord-292559-b21j9sf3 142 14 ] ] -RRB- cord-292559-b21j9sf3 142 15 , , , cord-292559-b21j9sf3 142 16 Philadelphia Philadelphia NNP cord-292559-b21j9sf3 142 17 Neurodevelopment Neurodevelopment NNP cord-292559-b21j9sf3 142 18 Cohort Cohort NNP cord-292559-b21j9sf3 142 19 ( ( -LRB- cord-292559-b21j9sf3 142 20 PNC PNC NNP cord-292559-b21j9sf3 142 21 ) ) -RRB- cord-292559-b21j9sf3 143 1 ( ( -LRB- cord-292559-b21j9sf3 143 2 N n NN cord-292559-b21j9sf3 143 3 = = SYM cord-292559-b21j9sf3 143 4 ~9498 ~9498 NN cord-292559-b21j9sf3 143 5 ) ) -RRB- cord-292559-b21j9sf3 143 6 [ [ -LRB- cord-292559-b21j9sf3 143 7 36 36 CD cord-292559-b21j9sf3 143 8 ] ] -RRB- cord-292559-b21j9sf3 143 9 , , , cord-292559-b21j9sf3 143 10 and and CC cord-292559-b21j9sf3 143 11 the the DT cord-292559-b21j9sf3 143 12 Dunedin Dunedin NNP cord-292559-b21j9sf3 143 13 Multidisciplinary Multidisciplinary NNP cord-292559-b21j9sf3 143 14 Health Health NNP cord-292559-b21j9sf3 143 15 and and CC cord-292559-b21j9sf3 143 16 Development Development NNP cord-292559-b21j9sf3 143 17 Study Study NNP cord-292559-b21j9sf3 143 18 ( ( -LRB- cord-292559-b21j9sf3 143 19 N n NN cord-292559-b21j9sf3 143 20 = = SYM cord-292559-b21j9sf3 143 21 1037 1037 CD cord-292559-b21j9sf3 143 22 ) ) -RRB- cord-292559-b21j9sf3 143 23 [ [ -LRB- cord-292559-b21j9sf3 143 24 37 37 CD cord-292559-b21j9sf3 143 25 ] ] -RRB- cord-292559-b21j9sf3 143 26 , , , cord-292559-b21j9sf3 143 27 among among IN cord-292559-b21j9sf3 143 28 others other NNS cord-292559-b21j9sf3 143 29 . . . cord-292559-b21j9sf3 144 1 As as IN cord-292559-b21j9sf3 144 2 can can MD cord-292559-b21j9sf3 144 3 be be VB cord-292559-b21j9sf3 144 4 seen see VBN cord-292559-b21j9sf3 144 5 in in IN cord-292559-b21j9sf3 144 6 Table Table NNP cord-292559-b21j9sf3 144 7 2 2 CD cord-292559-b21j9sf3 144 8 , , , cord-292559-b21j9sf3 144 9 in in IN cord-292559-b21j9sf3 144 10 general general JJ cord-292559-b21j9sf3 144 11 these these DT cord-292559-b21j9sf3 144 12 previous previous JJ cord-292559-b21j9sf3 144 13 studies study NNS cord-292559-b21j9sf3 144 14 were be VBD cord-292559-b21j9sf3 144 15 large large JJ cord-292559-b21j9sf3 144 16 ( ( -LRB- cord-292559-b21j9sf3 144 17 sample sample NN cord-292559-b21j9sf3 144 18 sizes size NNS cord-292559-b21j9sf3 144 19 > > XX cord-292559-b21j9sf3 144 20 800 800 CD cord-292559-b21j9sf3 144 21 ) ) -RRB- cord-292559-b21j9sf3 144 22 , , , cord-292559-b21j9sf3 144 23 examined examine VBD cord-292559-b21j9sf3 144 24 a a DT cord-292559-b21j9sf3 144 25 range range NN cord-292559-b21j9sf3 144 26 of of IN cord-292559-b21j9sf3 144 27 ages age NNS cord-292559-b21j9sf3 144 28 from from IN cord-292559-b21j9sf3 144 29 beginning begin VBG cord-292559-b21j9sf3 144 30 prenatally prenatally RB cord-292559-b21j9sf3 144 31 ( ( -LRB- cord-292559-b21j9sf3 144 32 Generation generation NN cord-292559-b21j9sf3 144 33 R r NN cord-292559-b21j9sf3 144 34 ) ) -RRB- cord-292559-b21j9sf3 144 35 to to IN cord-292559-b21j9sf3 144 36 adulthood adulthood NN cord-292559-b21j9sf3 144 37 populations population NNS cord-292559-b21j9sf3 144 38 ( ( -LRB- cord-292559-b21j9sf3 144 39 e.g. e.g. RB cord-292559-b21j9sf3 144 40 , , , cord-292559-b21j9sf3 144 41 HCP HCP NNP cord-292559-b21j9sf3 144 42 , , , cord-292559-b21j9sf3 144 43 UK UK NNP cord-292559-b21j9sf3 144 44 Biobank Biobank NNP cord-292559-b21j9sf3 144 45 ) ) -RRB- cord-292559-b21j9sf3 144 46 . . . cord-292559-b21j9sf3 145 1 Some some DT cord-292559-b21j9sf3 145 2 followed follow VBD cord-292559-b21j9sf3 145 3 the the DT cord-292559-b21j9sf3 145 4 sample sample NN cord-292559-b21j9sf3 145 5 longitudinally longitudinally RB cord-292559-b21j9sf3 145 6 ( ( -LRB- cord-292559-b21j9sf3 145 7 e.g. e.g. RB cord-292559-b21j9sf3 145 8 , , , cord-292559-b21j9sf3 145 9 IMAGEN IMAGEN NNP cord-292559-b21j9sf3 145 10 , , , cord-292559-b21j9sf3 145 11 UK UK NNP cord-292559-b21j9sf3 145 12 Biobank Biobank NNP cord-292559-b21j9sf3 145 13 , , , cord-292559-b21j9sf3 145 14 Generation Generation NNP cord-292559-b21j9sf3 145 15 R R NNP cord-292559-b21j9sf3 145 16 , , , cord-292559-b21j9sf3 145 17 Dunedin Dunedin NNP cord-292559-b21j9sf3 145 18 , , , cord-292559-b21j9sf3 145 19 NCANDA NCANDA NNP cord-292559-b21j9sf3 145 20 ) ) -RRB- cord-292559-b21j9sf3 145 21 , , , cord-292559-b21j9sf3 145 22 or or CC cord-292559-b21j9sf3 145 23 followed follow VBD cord-292559-b21j9sf3 145 24 a a DT cord-292559-b21j9sf3 145 25 subset subset NN cord-292559-b21j9sf3 145 26 longitudinally longitudinally RB cord-292559-b21j9sf3 145 27 ( ( -LRB- cord-292559-b21j9sf3 145 28 e.g. e.g. RB cord-292559-b21j9sf3 145 29 , , , cord-292559-b21j9sf3 145 30 PNC PNC NNP cord-292559-b21j9sf3 145 31 ) ) -RRB- cord-292559-b21j9sf3 145 32 . . . cord-292559-b21j9sf3 146 1 All all DT cord-292559-b21j9sf3 146 2 included include VBD cord-292559-b21j9sf3 146 3 neuroimaging neuroimaging NN cord-292559-b21j9sf3 146 4 data datum NNS cord-292559-b21j9sf3 146 5 ( ( -LRB- cord-292559-b21j9sf3 146 6 e.g. e.g. RB cord-292559-b21j9sf3 146 7 , , , cord-292559-b21j9sf3 146 8 IMAGEN IMAGEN NNP cord-292559-b21j9sf3 146 9 , , , cord-292559-b21j9sf3 146 10 PING PING NNP cord-292559-b21j9sf3 146 11 , , , cord-292559-b21j9sf3 146 12 NCANDA NCANDA NNP cord-292559-b21j9sf3 146 13 , , , cord-292559-b21j9sf3 146 14 HCP HCP NNP cord-292559-b21j9sf3 146 15 ; ; : cord-292559-b21j9sf3 146 16 note note VB cord-292559-b21j9sf3 146 17 the the DT cord-292559-b21j9sf3 146 18 Dunedin Dunedin NNP cord-292559-b21j9sf3 146 19 study study NN cord-292559-b21j9sf3 146 20 did do VBD cord-292559-b21j9sf3 146 21 not not RB cord-292559-b21j9sf3 146 22 collect collect VB cord-292559-b21j9sf3 146 23 neuroimaging neuroimaging NN cord-292559-b21j9sf3 146 24 data datum NNS cord-292559-b21j9sf3 146 25 during during IN cord-292559-b21j9sf3 146 26 childhood childhood NN cord-292559-b21j9sf3 146 27 or or CC cord-292559-b21j9sf3 146 28 adolescence adolescence NN cord-292559-b21j9sf3 146 29 ) ) -RRB- cord-292559-b21j9sf3 146 30 , , , cord-292559-b21j9sf3 146 31 or or CC cord-292559-b21j9sf3 146 32 included include VBD cord-292559-b21j9sf3 146 33 neuroimaging neuroimage VBG cord-292559-b21j9sf3 146 34 on on IN cord-292559-b21j9sf3 146 35 a a DT cord-292559-b21j9sf3 146 36 subset subset NN cord-292559-b21j9sf3 146 37 of of IN cord-292559-b21j9sf3 146 38 participants participant NNS cord-292559-b21j9sf3 146 39 ( ( -LRB- cord-292559-b21j9sf3 146 40 e.g. e.g. RB cord-292559-b21j9sf3 146 41 , , , cord-292559-b21j9sf3 146 42 PNC PNC NNP cord-292559-b21j9sf3 146 43 , , , cord-292559-b21j9sf3 146 44 UK UK NNP cord-292559-b21j9sf3 146 45 Biobank Biobank NNP cord-292559-b21j9sf3 146 46 ) ) -RRB- cord-292559-b21j9sf3 146 47 . . . cord-292559-b21j9sf3 147 1 Notably notably RB cord-292559-b21j9sf3 147 2 , , , cord-292559-b21j9sf3 147 3 several several JJ cord-292559-b21j9sf3 147 4 even even RB cord-292559-b21j9sf3 147 5 included include VBD cord-292559-b21j9sf3 147 6 longitudinal longitudinal JJ cord-292559-b21j9sf3 147 7 imaging imaging NN cord-292559-b21j9sf3 147 8 ( ( -LRB- cord-292559-b21j9sf3 147 9 e.g. e.g. RB cord-292559-b21j9sf3 147 10 , , , cord-292559-b21j9sf3 147 11 NCANDA NCANDA NNP cord-292559-b21j9sf3 147 12 , , , cord-292559-b21j9sf3 147 13 Generation Generation NNP cord-292559-b21j9sf3 147 14 R r NN cord-292559-b21j9sf3 147 15 , , , cord-292559-b21j9sf3 147 16 IMAGEN IMAGEN NNP cord-292559-b21j9sf3 147 17 ) ) -RRB- cord-292559-b21j9sf3 147 18 . . . cord-292559-b21j9sf3 148 1 The the DT cord-292559-b21j9sf3 148 2 ABCD ABCD NNP cord-292559-b21j9sf3 148 3 Study Study NNP cord-292559-b21j9sf3 148 4 complements complement VBZ cord-292559-b21j9sf3 148 5 and and CC cord-292559-b21j9sf3 148 6 extends extend VBZ cord-292559-b21j9sf3 148 7 beyond beyond IN cord-292559-b21j9sf3 148 8 these these DT cord-292559-b21j9sf3 148 9 other other JJ cord-292559-b21j9sf3 148 10 studies study NNS cord-292559-b21j9sf3 148 11 by by IN cord-292559-b21j9sf3 148 12 examining examine VBG cord-292559-b21j9sf3 148 13 measures measure NNS cord-292559-b21j9sf3 148 14 across across IN cord-292559-b21j9sf3 148 15 development development NN cord-292559-b21j9sf3 148 16 from from IN cord-292559-b21j9sf3 148 17 middle middle JJ cord-292559-b21j9sf3 148 18 childhood childhood NN cord-292559-b21j9sf3 148 19 - - , cord-292559-b21j9sf3 148 20 adulthood adulthood NN cord-292559-b21j9sf3 148 21 at at IN cord-292559-b21j9sf3 148 22 21 21 CD cord-292559-b21j9sf3 148 23 different different JJ cord-292559-b21j9sf3 148 24 sites site NNS cord-292559-b21j9sf3 148 25 across across IN cord-292559-b21j9sf3 148 26 the the DT cord-292559-b21j9sf3 148 27 U.S. U.S. NNP cord-292559-b21j9sf3 148 28 and and CC cord-292559-b21j9sf3 148 29 conducting conduct VBG cord-292559-b21j9sf3 148 30 assessments assessment NNS cord-292559-b21j9sf3 148 31 for for IN cord-292559-b21j9sf3 148 32 every every DT cord-292559-b21j9sf3 148 33 6 6 CD cord-292559-b21j9sf3 148 34 months month NNS cord-292559-b21j9sf3 148 35 and and CC cord-292559-b21j9sf3 148 36 imaging image VBG cord-292559-b21j9sf3 148 37 for for IN cord-292559-b21j9sf3 148 38 every every DT cord-292559-b21j9sf3 148 39 2 2 CD cord-292559-b21j9sf3 148 40 years year NNS cord-292559-b21j9sf3 148 41 . . . cord-292559-b21j9sf3 149 1 Furthermore furthermore RB cord-292559-b21j9sf3 149 2 , , , cord-292559-b21j9sf3 149 3 a a DT cord-292559-b21j9sf3 149 4 critical critical JJ cord-292559-b21j9sf3 149 5 component component NN cord-292559-b21j9sf3 149 6 of of IN cord-292559-b21j9sf3 149 7 the the DT cord-292559-b21j9sf3 149 8 ABCD ABCD NNP cord-292559-b21j9sf3 149 9 Study Study NNP cord-292559-b21j9sf3 149 10 is be VBZ cord-292559-b21j9sf3 149 11 the the DT cord-292559-b21j9sf3 149 12 open open JJ cord-292559-b21j9sf3 149 13 science science NN cord-292559-b21j9sf3 149 14 framework framework NN cord-292559-b21j9sf3 149 15 , , , cord-292559-b21j9sf3 149 16 whereby whereby WRB cord-292559-b21j9sf3 149 17 the the DT cord-292559-b21j9sf3 149 18 ABCD ABCD NNP cord-292559-b21j9sf3 149 19 Consortium Consortium NNP cord-292559-b21j9sf3 149 20 is be VBZ cord-292559-b21j9sf3 149 21 releasing release VBG cord-292559-b21j9sf3 149 22 data datum NNS cord-292559-b21j9sf3 149 23 collected collect VBN cord-292559-b21j9sf3 149 24 from from IN cord-292559-b21j9sf3 149 25 the the DT cord-292559-b21j9sf3 149 26 study study NN cord-292559-b21j9sf3 149 27 in in IN cord-292559-b21j9sf3 149 28 annual annual JJ cord-292559-b21j9sf3 149 29 data datum NNS cord-292559-b21j9sf3 149 30 releases release NNS cord-292559-b21j9sf3 149 31 to to IN cord-292559-b21j9sf3 149 32 the the DT cord-292559-b21j9sf3 149 33 scientific scientific JJ cord-292559-b21j9sf3 149 34 community community NN cord-292559-b21j9sf3 149 35 . . . cord-292559-b21j9sf3 150 1 This this DT cord-292559-b21j9sf3 150 2 approach approach NN cord-292559-b21j9sf3 150 3 builds build VBZ cord-292559-b21j9sf3 150 4 upon upon IN cord-292559-b21j9sf3 150 5 the the DT cord-292559-b21j9sf3 150 6 open open JJ cord-292559-b21j9sf3 150 7 science science NN cord-292559-b21j9sf3 150 8 framework framework NN cord-292559-b21j9sf3 150 9 of of IN cord-292559-b21j9sf3 150 10 release release NN cord-292559-b21j9sf3 150 11 while while IN cord-292559-b21j9sf3 150 12 data datum NNS cord-292559-b21j9sf3 150 13 is be VBZ cord-292559-b21j9sf3 150 14 still still RB cord-292559-b21j9sf3 150 15 being be VBG cord-292559-b21j9sf3 150 16 collected collect VBN cord-292559-b21j9sf3 150 17 pioneered pioneer VBN cord-292559-b21j9sf3 150 18 by by IN cord-292559-b21j9sf3 150 19 a a DT cord-292559-b21j9sf3 150 20 number number NN cord-292559-b21j9sf3 150 21 of of IN cord-292559-b21j9sf3 150 22 previous previous JJ cord-292559-b21j9sf3 150 23 studies study NNS cord-292559-b21j9sf3 150 24 , , , cord-292559-b21j9sf3 150 25 including include VBG cord-292559-b21j9sf3 150 26 the the DT cord-292559-b21j9sf3 150 27 HCP HCP NNP cord-292559-b21j9sf3 150 28 and and CC cord-292559-b21j9sf3 150 29 UK UK NNP cord-292559-b21j9sf3 150 30 Biobank Biobank NNP cord-292559-b21j9sf3 150 31 projects project NNS cord-292559-b21j9sf3 150 32 . . . cord-292559-b21j9sf3 151 1 Overview overview NN cord-292559-b21j9sf3 151 2 of of IN cord-292559-b21j9sf3 151 3 emerging emerge VBG cord-292559-b21j9sf3 151 4 findings finding NNS cord-292559-b21j9sf3 151 5 from from IN cord-292559-b21j9sf3 151 6 the the DT cord-292559-b21j9sf3 151 7 ABCD ABCD NNP cord-292559-b21j9sf3 151 8 Study Study NNP cord-292559-b21j9sf3 152 1 The the DT cord-292559-b21j9sf3 152 2 ABCD ABCD NNP cord-292559-b21j9sf3 152 3 Study Study NNP cord-292559-b21j9sf3 152 4 has have VBZ cord-292559-b21j9sf3 152 5 submitted submit VBN cord-292559-b21j9sf3 152 6 two two CD cord-292559-b21j9sf3 152 7 data datum NNS cord-292559-b21j9sf3 152 8 releases release NNS cord-292559-b21j9sf3 152 9 , , , cord-292559-b21j9sf3 152 10 and and CC cord-292559-b21j9sf3 152 11 numerous numerous JJ cord-292559-b21j9sf3 152 12 investigators investigator NNS cord-292559-b21j9sf3 152 13 both both DT cord-292559-b21j9sf3 152 14 within within IN cord-292559-b21j9sf3 152 15 the the DT cord-292559-b21j9sf3 152 16 consortium consortium NN cord-292559-b21j9sf3 152 17 and and CC cord-292559-b21j9sf3 152 18 from from IN cord-292559-b21j9sf3 152 19 without without IN cord-292559-b21j9sf3 152 20 have have VBP cord-292559-b21j9sf3 152 21 been be VBN cord-292559-b21j9sf3 152 22 utilizing utilize VBG cord-292559-b21j9sf3 152 23 these these DT cord-292559-b21j9sf3 152 24 data datum NNS cord-292559-b21j9sf3 152 25 to to TO cord-292559-b21j9sf3 152 26 begin begin VB cord-292559-b21j9sf3 152 27 to to TO cord-292559-b21j9sf3 152 28 address address VB cord-292559-b21j9sf3 152 29 questions question NNS cord-292559-b21j9sf3 152 30 relevant relevant JJ cord-292559-b21j9sf3 152 31 to to IN cord-292559-b21j9sf3 152 32 both both CC cord-292559-b21j9sf3 152 33 healthy healthy JJ cord-292559-b21j9sf3 152 34 and and CC cord-292559-b21j9sf3 152 35 disordered disordered JJ cord-292559-b21j9sf3 152 36 brain brain NN cord-292559-b21j9sf3 152 37 and and CC cord-292559-b21j9sf3 152 38 behavioral behavioral JJ cord-292559-b21j9sf3 152 39 relationships relationship NNS cord-292559-b21j9sf3 152 40 . . . cord-292559-b21j9sf3 153 1 Here here RB cord-292559-b21j9sf3 153 2 , , , cord-292559-b21j9sf3 153 3 we -PRON- PRP cord-292559-b21j9sf3 153 4 provide provide VBP cord-292559-b21j9sf3 153 5 a a DT cord-292559-b21j9sf3 153 6 selective selective JJ cord-292559-b21j9sf3 153 7 review review NN cord-292559-b21j9sf3 153 8 of of IN cord-292559-b21j9sf3 153 9 some some DT cord-292559-b21j9sf3 153 10 of of IN cord-292559-b21j9sf3 153 11 this this DT cord-292559-b21j9sf3 153 12 emerging emerge VBG cord-292559-b21j9sf3 153 13 research research NN cord-292559-b21j9sf3 153 14 . . . cord-292559-b21j9sf3 154 1 Notably notably RB cord-292559-b21j9sf3 154 2 , , , cord-292559-b21j9sf3 154 3 the the DT cord-292559-b21j9sf3 154 4 majority majority NN cord-292559-b21j9sf3 154 5 of of IN cord-292559-b21j9sf3 154 6 the the DT cord-292559-b21j9sf3 154 7 published publish VBN cord-292559-b21j9sf3 154 8 emerging emerge VBG cord-292559-b21j9sf3 154 9 work work NN cord-292559-b21j9sf3 154 10 to to IN cord-292559-b21j9sf3 154 11 date date NN cord-292559-b21j9sf3 154 12 is be VBZ cord-292559-b21j9sf3 154 13 cross cross JJ cord-292559-b21j9sf3 154 14 - - JJ cord-292559-b21j9sf3 154 15 sectional sectional JJ cord-292559-b21j9sf3 154 16 and and CC cord-292559-b21j9sf3 154 17 focused focus VBD cord-292559-b21j9sf3 154 18 on on IN cord-292559-b21j9sf3 154 19 the the DT cord-292559-b21j9sf3 154 20 initial initial JJ cord-292559-b21j9sf3 154 21 baseline baseline JJ cord-292559-b21j9sf3 154 22 data datum NNS cord-292559-b21j9sf3 154 23 set set NN cord-292559-b21j9sf3 154 24 . . . cord-292559-b21j9sf3 155 1 The the DT cord-292559-b21j9sf3 155 2 ABCD ABCD NNP cord-292559-b21j9sf3 155 3 study study NN cord-292559-b21j9sf3 155 4 : : : cord-292559-b21j9sf3 155 5 understanding understand VBG cord-292559-b21j9sf3 155 6 the the DT cord-292559-b21j9sf3 155 7 development development NN cord-292559-b21j9sf3 155 8 of of IN cord-292559-b21j9sf3 155 9 risk risk NN cord-292559-b21j9sf3 155 10 for for IN cord-292559-b21j9sf3 155 11 mental mental JJ cord-292559-b21j9sf3 155 12 and and CC cord-292559-b21j9sf3 155 13 . . . cord-292559-b21j9sf3 155 14 . . . cord-292559-b21j9sf3 155 15 . . . cord-292559-b21j9sf3 156 1 However however RB cord-292559-b21j9sf3 156 2 , , , cord-292559-b21j9sf3 156 3 several several JJ cord-292559-b21j9sf3 156 4 emerging emerge VBG cord-292559-b21j9sf3 156 5 studies study NNS cord-292559-b21j9sf3 156 6 have have VBP cord-292559-b21j9sf3 156 7 utilized utilize VBN cord-292559-b21j9sf3 156 8 the the DT cord-292559-b21j9sf3 156 9 partial partial JJ cord-292559-b21j9sf3 156 10 data datum NNS cord-292559-b21j9sf3 156 11 available available JJ cord-292559-b21j9sf3 156 12 from from IN cord-292559-b21j9sf3 156 13 year year NN cord-292559-b21j9sf3 156 14 1 1 CD cord-292559-b21j9sf3 156 15 [ [ -LRB- cord-292559-b21j9sf3 156 16 38 38 CD cord-292559-b21j9sf3 156 17 , , , cord-292559-b21j9sf3 156 18 39 39 CD cord-292559-b21j9sf3 156 19 ] ] -RRB- cord-292559-b21j9sf3 156 20 . . . cord-292559-b21j9sf3 157 1 ABCD ABCD NNP cord-292559-b21j9sf3 157 2 release release NN cord-292559-b21j9sf3 157 3 3.0 3.0 CD cord-292559-b21j9sf3 157 4 is be VBZ cord-292559-b21j9sf3 157 5 slated slate VBN cord-292559-b21j9sf3 157 6 for for IN cord-292559-b21j9sf3 157 7 release release NN cord-292559-b21j9sf3 157 8 during during IN cord-292559-b21j9sf3 157 9 August August NNP cord-292559-b21j9sf3 157 10 2020 2020 CD cord-292559-b21j9sf3 157 11 , , , cord-292559-b21j9sf3 157 12 and and CC cord-292559-b21j9sf3 157 13 will will MD cord-292559-b21j9sf3 157 14 include include VB cord-292559-b21j9sf3 157 15 the the DT cord-292559-b21j9sf3 157 16 entire entire JJ cord-292559-b21j9sf3 157 17 year year NN cord-292559-b21j9sf3 157 18 1 1 CD cord-292559-b21j9sf3 157 19 and and CC cord-292559-b21j9sf3 157 20 part part NN cord-292559-b21j9sf3 157 21 of of IN cord-292559-b21j9sf3 157 22 year year NN cord-292559-b21j9sf3 157 23 2 2 CD cord-292559-b21j9sf3 157 24 , , , cord-292559-b21j9sf3 157 25 which which WDT cord-292559-b21j9sf3 157 26 will will MD cord-292559-b21j9sf3 157 27 include include VB cord-292559-b21j9sf3 157 28 repeated repeat VBN cord-292559-b21j9sf3 157 29 neuroimaging neuroimage VBG cord-292559-b21j9sf3 157 30 assessments assessment NNS cord-292559-b21j9sf3 157 31 . . . cord-292559-b21j9sf3 158 1 These these DT cord-292559-b21j9sf3 158 2 emerging emerge VBG cord-292559-b21j9sf3 158 3 studies study NNS cord-292559-b21j9sf3 158 4 vary vary VBP cord-292559-b21j9sf3 158 5 in in IN cord-292559-b21j9sf3 158 6 scientific scientific JJ cord-292559-b21j9sf3 158 7 rigor rigor NN cord-292559-b21j9sf3 158 8 , , , cord-292559-b21j9sf3 158 9 including include VBG cord-292559-b21j9sf3 158 10 using use VBG cord-292559-b21j9sf3 158 11 appropriate appropriate JJ cord-292559-b21j9sf3 158 12 analytic analytic JJ cord-292559-b21j9sf3 158 13 methods method NNS cord-292559-b21j9sf3 158 14 ( ( -LRB- cord-292559-b21j9sf3 158 15 e.g. e.g. RB cord-292559-b21j9sf3 158 16 , , , cord-292559-b21j9sf3 158 17 nested nested JJ cord-292559-b21j9sf3 158 18 models model NNS cord-292559-b21j9sf3 158 19 ) ) -RRB- cord-292559-b21j9sf3 158 20 , , , cord-292559-b21j9sf3 158 21 using use VBG cord-292559-b21j9sf3 158 22 rigorous rigorous JJ cord-292559-b21j9sf3 158 23 multiple multiple JJ cord-292559-b21j9sf3 158 24 comparison comparison NN cord-292559-b21j9sf3 158 25 control control NN cord-292559-b21j9sf3 158 26 , , , cord-292559-b21j9sf3 158 27 controlling control VBG cord-292559-b21j9sf3 158 28 for for IN cord-292559-b21j9sf3 158 29 potential potential JJ cord-292559-b21j9sf3 158 30 confounds confound NNS cord-292559-b21j9sf3 158 31 ( ( -LRB- cord-292559-b21j9sf3 158 32 e.g. e.g. RB cord-292559-b21j9sf3 158 33 , , , cord-292559-b21j9sf3 158 34 age age NN cord-292559-b21j9sf3 158 35 , , , cord-292559-b21j9sf3 158 36 sex sex NN cord-292559-b21j9sf3 158 37 , , , cord-292559-b21j9sf3 158 38 race race NN cord-292559-b21j9sf3 158 39 / / SYM cord-292559-b21j9sf3 158 40 ethnicity ethnicity NN cord-292559-b21j9sf3 158 41 , , , cord-292559-b21j9sf3 158 42 and and CC cord-292559-b21j9sf3 158 43 SES SES NNP cord-292559-b21j9sf3 158 44 ) ) -RRB- cord-292559-b21j9sf3 158 45 , , , cord-292559-b21j9sf3 158 46 and and CC cord-292559-b21j9sf3 158 47 replicating replicate VBG cord-292559-b21j9sf3 158 48 findings finding NNS cord-292559-b21j9sf3 158 49 . . . cord-292559-b21j9sf3 159 1 Several several JJ cord-292559-b21j9sf3 159 2 of of IN cord-292559-b21j9sf3 159 3 the the DT cord-292559-b21j9sf3 159 4 emerging emerge VBG cord-292559-b21j9sf3 159 5 studies study NNS cord-292559-b21j9sf3 159 6 have have VBP cord-292559-b21j9sf3 159 7 implemented implement VBN cord-292559-b21j9sf3 159 8 each each DT cord-292559-b21j9sf3 159 9 of of IN cord-292559-b21j9sf3 159 10 these these DT cord-292559-b21j9sf3 159 11 rigorous rigorous JJ cord-292559-b21j9sf3 159 12 inclusions inclusion NNS cord-292559-b21j9sf3 159 13 [ [ -LRB- cord-292559-b21j9sf3 159 14 40 40 CD cord-292559-b21j9sf3 159 15 ] ] -RRB- cord-292559-b21j9sf3 159 16 [ [ -LRB- cord-292559-b21j9sf3 159 17 41 41 CD cord-292559-b21j9sf3 159 18 ] ] -RRB- cord-292559-b21j9sf3 159 19 [ [ -LRB- cord-292559-b21j9sf3 159 20 42 42 CD cord-292559-b21j9sf3 159 21 ] ] -RRB- cord-292559-b21j9sf3 159 22 [ [ -LRB- cord-292559-b21j9sf3 159 23 43 43 CD cord-292559-b21j9sf3 159 24 ] ] -RRB- cord-292559-b21j9sf3 159 25 , , , cord-292559-b21j9sf3 159 26 and and CC cord-292559-b21j9sf3 159 27 88 88 CD cord-292559-b21j9sf3 159 28 % % NN cord-292559-b21j9sf3 159 29 included include VBN cord-292559-b21j9sf3 159 30 at at IN cord-292559-b21j9sf3 159 31 least least RBS cord-292559-b21j9sf3 159 32 one one CD cord-292559-b21j9sf3 159 33 of of IN cord-292559-b21j9sf3 159 34 these these DT cord-292559-b21j9sf3 159 35 methodologies methodology NNS cord-292559-b21j9sf3 159 36 / / SYM cord-292559-b21j9sf3 159 37 techniques technique NNS cord-292559-b21j9sf3 159 38 . . . cord-292559-b21j9sf3 160 1 Emerging emerge VBG cord-292559-b21j9sf3 160 2 studies study NNS cord-292559-b21j9sf3 160 3 from from IN cord-292559-b21j9sf3 160 4 the the DT cord-292559-b21j9sf3 160 5 ABCD ABCD NNP cord-292559-b21j9sf3 160 6 Study Study NNP cord-292559-b21j9sf3 160 7 have have VBP cord-292559-b21j9sf3 160 8 been be VBN cord-292559-b21j9sf3 160 9 utilizing utilize VBG cord-292559-b21j9sf3 160 10 a a DT cord-292559-b21j9sf3 160 11 variety variety NN cord-292559-b21j9sf3 160 12 of of IN cord-292559-b21j9sf3 160 13 measures measure NNS cord-292559-b21j9sf3 160 14 to to TO cord-292559-b21j9sf3 160 15 examine examine VB cord-292559-b21j9sf3 160 16 an an DT cord-292559-b21j9sf3 160 17 array array NN cord-292559-b21j9sf3 160 18 of of IN cord-292559-b21j9sf3 160 19 both both CC cord-292559-b21j9sf3 160 20 adaptive adaptive JJ cord-292559-b21j9sf3 160 21 and and CC cord-292559-b21j9sf3 160 22 maladaptive maladaptive JJ cord-292559-b21j9sf3 160 23 aspects aspect NNS cord-292559-b21j9sf3 160 24 of of IN cord-292559-b21j9sf3 160 25 cognitive cognitive JJ cord-292559-b21j9sf3 160 26 , , , cord-292559-b21j9sf3 160 27 social social JJ cord-292559-b21j9sf3 160 28 , , , cord-292559-b21j9sf3 160 29 emotional emotional JJ cord-292559-b21j9sf3 160 30 , , , cord-292559-b21j9sf3 160 31 and and CC cord-292559-b21j9sf3 160 32 neural neural JJ cord-292559-b21j9sf3 160 33 correlates correlate VBZ cord-292559-b21j9sf3 160 34 in in IN cord-292559-b21j9sf3 160 35 middle middle JJ cord-292559-b21j9sf3 160 36 childhood childhood NN cord-292559-b21j9sf3 160 37 [ [ -LRB- cord-292559-b21j9sf3 160 38 1 1 CD cord-292559-b21j9sf3 160 39 , , , cord-292559-b21j9sf3 160 40 7 7 CD cord-292559-b21j9sf3 160 41 - - SYM cord-292559-b21j9sf3 160 42 9 9 CD cord-292559-b21j9sf3 160 43 , , , cord-292559-b21j9sf3 160 44 17 17 CD cord-292559-b21j9sf3 160 45 , , , cord-292559-b21j9sf3 160 46 18 18 CD cord-292559-b21j9sf3 160 47 ] ] -RRB- cord-292559-b21j9sf3 160 48 . . . cord-292559-b21j9sf3 161 1 Many many JJ cord-292559-b21j9sf3 161 2 of of IN cord-292559-b21j9sf3 161 3 the the DT cord-292559-b21j9sf3 161 4 measures measure NNS cord-292559-b21j9sf3 161 5 already already RB cord-292559-b21j9sf3 161 6 have have VBP cord-292559-b21j9sf3 161 7 extensive extensive JJ cord-292559-b21j9sf3 161 8 psychometric psychometric JJ cord-292559-b21j9sf3 161 9 data datum NNS cord-292559-b21j9sf3 161 10 . . . cord-292559-b21j9sf3 162 1 However however RB cord-292559-b21j9sf3 162 2 , , , cord-292559-b21j9sf3 162 3 in in IN cord-292559-b21j9sf3 162 4 some some DT cord-292559-b21j9sf3 162 5 cases case NNS cord-292559-b21j9sf3 162 6 , , , cord-292559-b21j9sf3 162 7 measures measure NNS cord-292559-b21j9sf3 162 8 were be VBD cord-292559-b21j9sf3 162 9 shortened shorten VBN cord-292559-b21j9sf3 162 10 to to TO cord-292559-b21j9sf3 162 11 reduce reduce VB cord-292559-b21j9sf3 162 12 participant participant NN cord-292559-b21j9sf3 162 13 burden burden NN cord-292559-b21j9sf3 162 14 , , , cord-292559-b21j9sf3 162 15 adapted adapt VBN cord-292559-b21j9sf3 162 16 for for IN cord-292559-b21j9sf3 162 17 use use NN cord-292559-b21j9sf3 162 18 in in IN cord-292559-b21j9sf3 162 19 a a DT cord-292559-b21j9sf3 162 20 younger young JJR cord-292559-b21j9sf3 162 21 population population NN cord-292559-b21j9sf3 162 22 , , , cord-292559-b21j9sf3 162 23 or or CC cord-292559-b21j9sf3 162 24 created create VBN cord-292559-b21j9sf3 162 25 from from IN cord-292559-b21j9sf3 162 26 items item NNS cord-292559-b21j9sf3 162 27 selected select VBN cord-292559-b21j9sf3 162 28 from from IN cord-292559-b21j9sf3 162 29 various various JJ cord-292559-b21j9sf3 162 30 other other JJ cord-292559-b21j9sf3 162 31 scales scale NNS cord-292559-b21j9sf3 162 32 . . . cord-292559-b21j9sf3 163 1 As as IN cord-292559-b21j9sf3 163 2 such such JJ cord-292559-b21j9sf3 163 3 , , , cord-292559-b21j9sf3 163 4 several several JJ cord-292559-b21j9sf3 163 5 early early JJ cord-292559-b21j9sf3 163 6 emerging emerge VBG cord-292559-b21j9sf3 163 7 studies study NNS cord-292559-b21j9sf3 163 8 from from IN cord-292559-b21j9sf3 163 9 the the DT cord-292559-b21j9sf3 163 10 ABCD ABCD NNP cord-292559-b21j9sf3 163 11 Study Study NNP cord-292559-b21j9sf3 163 12 have have VBP cord-292559-b21j9sf3 163 13 examined examine VBN cord-292559-b21j9sf3 163 14 psychometric psychometric JJ cord-292559-b21j9sf3 163 15 properties property NNS cord-292559-b21j9sf3 163 16 and and CC cord-292559-b21j9sf3 163 17 validity validity NN cord-292559-b21j9sf3 163 18 for for IN cord-292559-b21j9sf3 163 19 several several JJ cord-292559-b21j9sf3 163 20 measures measure NNS cord-292559-b21j9sf3 163 21 [ [ -LRB- cord-292559-b21j9sf3 163 22 44 44 CD cord-292559-b21j9sf3 163 23 , , , cord-292559-b21j9sf3 163 24 45 45 CD cord-292559-b21j9sf3 163 25 ] ] -RRB- cord-292559-b21j9sf3 163 26 . . . cord-292559-b21j9sf3 164 1 Further further RB cord-292559-b21j9sf3 164 2 , , , cord-292559-b21j9sf3 164 3 emerging emerge VBG cord-292559-b21j9sf3 164 4 studies study NNS cord-292559-b21j9sf3 164 5 have have VBP cord-292559-b21j9sf3 164 6 begun begin VBN cord-292559-b21j9sf3 164 7 to to TO cord-292559-b21j9sf3 164 8 utilize utilize VB cord-292559-b21j9sf3 164 9 the the DT cord-292559-b21j9sf3 164 10 large large JJ cord-292559-b21j9sf3 164 11 sample sample NN cord-292559-b21j9sf3 164 12 to to TO cord-292559-b21j9sf3 164 13 create create VB cord-292559-b21j9sf3 164 14 short short JJ cord-292559-b21j9sf3 164 15 forms form NNS cord-292559-b21j9sf3 164 16 [ [ -LRB- cord-292559-b21j9sf3 164 17 38 38 CD cord-292559-b21j9sf3 164 18 ] ] -RRB- cord-292559-b21j9sf3 164 19 . . . cord-292559-b21j9sf3 165 1 These these DT cord-292559-b21j9sf3 165 2 emerging emerge VBG cord-292559-b21j9sf3 165 3 studies study NNS cord-292559-b21j9sf3 165 4 highlight highlight VBP cord-292559-b21j9sf3 165 5 several several JJ cord-292559-b21j9sf3 165 6 exciting exciting JJ cord-292559-b21j9sf3 165 7 avenues avenue NNS cord-292559-b21j9sf3 165 8 for for IN cord-292559-b21j9sf3 165 9 examining examine VBG cord-292559-b21j9sf3 165 10 the the DT cord-292559-b21j9sf3 165 11 properties property NNS cord-292559-b21j9sf3 165 12 and and CC cord-292559-b21j9sf3 165 13 novel novel NN cord-292559-b21j9sf3 165 14 uses use NNS cord-292559-b21j9sf3 165 15 of of IN cord-292559-b21j9sf3 165 16 the the DT cord-292559-b21j9sf3 165 17 ABCD ABCD NNP cord-292559-b21j9sf3 165 18 Study Study NNP cord-292559-b21j9sf3 165 19 measures measure NNS cord-292559-b21j9sf3 165 20 . . . cord-292559-b21j9sf3 166 1 One one CD cord-292559-b21j9sf3 166 2 of of IN cord-292559-b21j9sf3 166 3 the the DT cord-292559-b21j9sf3 166 4 first first JJ cord-292559-b21j9sf3 166 5 emerging emerge VBG cord-292559-b21j9sf3 166 6 studies study NNS cord-292559-b21j9sf3 166 7 to to TO cord-292559-b21j9sf3 166 8 analyze analyze VB cord-292559-b21j9sf3 166 9 ABCD ABCD NNP cord-292559-b21j9sf3 166 10 Study Study NNP cord-292559-b21j9sf3 166 11 baseline baseline JJ cord-292559-b21j9sf3 166 12 data datum NNS cord-292559-b21j9sf3 166 13 examined examine VBD cord-292559-b21j9sf3 166 14 the the DT cord-292559-b21j9sf3 166 15 properties property NNS cord-292559-b21j9sf3 166 16 and and CC cord-292559-b21j9sf3 166 17 conducted conduct VBD cord-292559-b21j9sf3 166 18 some some DT cord-292559-b21j9sf3 166 19 initial initial JJ cord-292559-b21j9sf3 166 20 validation validation NN cord-292559-b21j9sf3 166 21 analyses analysis NNS cord-292559-b21j9sf3 166 22 for for IN cord-292559-b21j9sf3 166 23 a a DT cord-292559-b21j9sf3 166 24 measure measure NN cord-292559-b21j9sf3 166 25 of of IN cord-292559-b21j9sf3 166 26 PLEs ple NNS cord-292559-b21j9sf3 166 27 entitled entitle VBN cord-292559-b21j9sf3 166 28 the the DT cord-292559-b21j9sf3 166 29 Prodromal Prodromal NNP cord-292559-b21j9sf3 166 30 Questionnaire Questionnaire NNP cord-292559-b21j9sf3 166 31 - - HYPH cord-292559-b21j9sf3 166 32 Brief Brief NNP cord-292559-b21j9sf3 166 33 Child Child NNP cord-292559-b21j9sf3 166 34 Version Version NNP cord-292559-b21j9sf3 166 35 ( ( -LRB- cord-292559-b21j9sf3 166 36 PQ PQ NNP cord-292559-b21j9sf3 166 37 - - HYPH cord-292559-b21j9sf3 166 38 BC BC NNP cord-292559-b21j9sf3 166 39 ) ) -RRB- cord-292559-b21j9sf3 166 40 [ [ -LRB- cord-292559-b21j9sf3 166 41 44 44 CD cord-292559-b21j9sf3 166 42 ] ] -RRB- cord-292559-b21j9sf3 166 43 , , , cord-292559-b21j9sf3 166 44 including include VBG cord-292559-b21j9sf3 166 45 conducting conduct VBG cord-292559-b21j9sf3 166 46 measurement measurement NN cord-292559-b21j9sf3 166 47 invariance invariance NN cord-292559-b21j9sf3 166 48 analyses analysis NNS cord-292559-b21j9sf3 166 49 and and CC cord-292559-b21j9sf3 166 50 finding find VBG cord-292559-b21j9sf3 166 51 the the DT cord-292559-b21j9sf3 166 52 PQ PQ NNP cord-292559-b21j9sf3 166 53 - - HYPH cord-292559-b21j9sf3 166 54 BC BC NNP cord-292559-b21j9sf3 166 55 functioned function VBD cord-292559-b21j9sf3 166 56 similarly similarly RB cord-292559-b21j9sf3 166 57 across across IN cord-292559-b21j9sf3 166 58 sex sex NN cord-292559-b21j9sf3 166 59 and and CC cord-292559-b21j9sf3 166 60 race race NN cord-292559-b21j9sf3 166 61 / / SYM cord-292559-b21j9sf3 166 62 ethnicity ethnicity NN cord-292559-b21j9sf3 166 63 . . . cord-292559-b21j9sf3 167 1 Another another DT cord-292559-b21j9sf3 167 2 recent recent JJ cord-292559-b21j9sf3 167 3 emerging emerge VBG cord-292559-b21j9sf3 167 4 study study NN cord-292559-b21j9sf3 167 5 conducted conduct VBN cord-292559-b21j9sf3 167 6 item item NN cord-292559-b21j9sf3 167 7 response response NN cord-292559-b21j9sf3 167 8 theory theory NN cord-292559-b21j9sf3 167 9 analyses analyse VBZ cord-292559-b21j9sf3 167 10 on on IN cord-292559-b21j9sf3 167 11 the the DT cord-292559-b21j9sf3 167 12 PQ PQ NNP cord-292559-b21j9sf3 167 13 - - HYPH cord-292559-b21j9sf3 167 14 BC BC NNP cord-292559-b21j9sf3 167 15 and and CC cord-292559-b21j9sf3 167 16 used use VBD cord-292559-b21j9sf3 167 17 information information NN cord-292559-b21j9sf3 167 18 gleaned glean VBN cord-292559-b21j9sf3 167 19 from from IN cord-292559-b21j9sf3 167 20 these these DT cord-292559-b21j9sf3 167 21 analyses analysis NNS cord-292559-b21j9sf3 167 22 to to TO cord-292559-b21j9sf3 167 23 begin begin VB cord-292559-b21j9sf3 167 24 the the DT cord-292559-b21j9sf3 167 25 process process NN cord-292559-b21j9sf3 167 26 of of IN cord-292559-b21j9sf3 167 27 creating create VBG cord-292559-b21j9sf3 167 28 a a DT cord-292559-b21j9sf3 167 29 short short JJ cord-292559-b21j9sf3 167 30 form form NN cord-292559-b21j9sf3 167 31 that that WDT cord-292559-b21j9sf3 167 32 theoretically theoretically RB cord-292559-b21j9sf3 167 33 can can MD cord-292559-b21j9sf3 167 34 be be VB cord-292559-b21j9sf3 167 35 used use VBN cord-292559-b21j9sf3 167 36 for for IN cord-292559-b21j9sf3 167 37 future future JJ cord-292559-b21j9sf3 167 38 clinical clinical JJ cord-292559-b21j9sf3 167 39 purposes purpose NNS cord-292559-b21j9sf3 167 40 [ [ -LRB- cord-292559-b21j9sf3 167 41 38 38 CD cord-292559-b21j9sf3 167 42 ] ] -RRB- cord-292559-b21j9sf3 167 43 . . . cord-292559-b21j9sf3 168 1 Similarly similarly RB cord-292559-b21j9sf3 168 2 , , , cord-292559-b21j9sf3 168 3 another another DT cord-292559-b21j9sf3 168 4 emerging emerge VBG cord-292559-b21j9sf3 168 5 study study NN cord-292559-b21j9sf3 168 6 examined examine VBD cord-292559-b21j9sf3 168 7 validity validity NN cord-292559-b21j9sf3 168 8 evidence evidence NN cord-292559-b21j9sf3 168 9 for for IN cord-292559-b21j9sf3 168 10 a a DT cord-292559-b21j9sf3 168 11 novel novel NN cord-292559-b21j9sf3 168 12 , , , cord-292559-b21j9sf3 168 13 abbreviated abbreviated JJ cord-292559-b21j9sf3 168 14 measure measure NN cord-292559-b21j9sf3 168 15 of of IN cord-292559-b21j9sf3 168 16 impulsivity impulsivity NN cord-292559-b21j9sf3 168 17 in in IN cord-292559-b21j9sf3 168 18 youth youth NN cord-292559-b21j9sf3 168 19 , , , cord-292559-b21j9sf3 168 20 the the DT cord-292559-b21j9sf3 168 21 UPPS UPPS NNP cord-292559-b21j9sf3 168 22 - - HYPH cord-292559-b21j9sf3 168 23 P P NNP cord-292559-b21j9sf3 168 24 Impulsive impulsive JJ cord-292559-b21j9sf3 168 25 Behavior behavior NN cord-292559-b21j9sf3 168 26 Scale scale VB cord-292559-b21j9sf3 168 27 [ [ -LRB- cord-292559-b21j9sf3 168 28 45 45 CD cord-292559-b21j9sf3 168 29 ] ] -RRB- cord-292559-b21j9sf3 168 30 . . . cord-292559-b21j9sf3 169 1 The the DT cord-292559-b21j9sf3 169 2 authors author NNS cord-292559-b21j9sf3 169 3 found find VBD cord-292559-b21j9sf3 169 4 adequate adequate JJ cord-292559-b21j9sf3 169 5 measurement measurement NN cord-292559-b21j9sf3 169 6 invariance invariance NN cord-292559-b21j9sf3 169 7 across across IN cord-292559-b21j9sf3 169 8 gender gender NN cord-292559-b21j9sf3 169 9 , , , cord-292559-b21j9sf3 169 10 race race NN cord-292559-b21j9sf3 169 11 / / SYM cord-292559-b21j9sf3 169 12 ethnicity ethnicity NN cord-292559-b21j9sf3 169 13 , , , cord-292559-b21j9sf3 169 14 household household NN cord-292559-b21j9sf3 169 15 income income NN cord-292559-b21j9sf3 169 16 , , , cord-292559-b21j9sf3 169 17 and and CC cord-292559-b21j9sf3 169 18 parental parental JJ cord-292559-b21j9sf3 169 19 education education NN cord-292559-b21j9sf3 169 20 , , , cord-292559-b21j9sf3 169 21 and and CC cord-292559-b21j9sf3 169 22 examined examine VBN cord-292559-b21j9sf3 169 23 convergent convergent JJ cord-292559-b21j9sf3 169 24 and and CC cord-292559-b21j9sf3 169 25 discriminant discriminant JJ cord-292559-b21j9sf3 169 26 validity validity NN cord-292559-b21j9sf3 169 27 across across IN cord-292559-b21j9sf3 169 28 a a DT cord-292559-b21j9sf3 169 29 number number NN cord-292559-b21j9sf3 169 30 of of IN cord-292559-b21j9sf3 169 31 relevant relevant JJ cord-292559-b21j9sf3 169 32 characteristics characteristic NNS cord-292559-b21j9sf3 169 33 , , , cord-292559-b21j9sf3 169 34 including include VBG cord-292559-b21j9sf3 169 35 youth youth NN cord-292559-b21j9sf3 169 36 - - HYPH cord-292559-b21j9sf3 169 37 reported report VBN cord-292559-b21j9sf3 169 38 and and CC cord-292559-b21j9sf3 169 39 parentreported parentreported JJ cord-292559-b21j9sf3 169 40 psychopathology psychopathology NN cord-292559-b21j9sf3 169 41 and and CC cord-292559-b21j9sf3 169 42 measures measure NNS cord-292559-b21j9sf3 169 43 of of IN cord-292559-b21j9sf3 169 44 cognition cognition NN cord-292559-b21j9sf3 169 45 . . . cord-292559-b21j9sf3 170 1 Lastly lastly RB cord-292559-b21j9sf3 170 2 , , , cord-292559-b21j9sf3 170 3 researchers researcher NNS cord-292559-b21j9sf3 170 4 also also RB cord-292559-b21j9sf3 170 5 used use VBD cord-292559-b21j9sf3 170 6 ABCD ABCD NNP cord-292559-b21j9sf3 170 7 Study Study NNP cord-292559-b21j9sf3 170 8 measures measure NNS cord-292559-b21j9sf3 170 9 to to TO cord-292559-b21j9sf3 170 10 create create VB cord-292559-b21j9sf3 170 11 a a DT cord-292559-b21j9sf3 170 12 4-item 4-item CD cord-292559-b21j9sf3 170 13 measure measure NN cord-292559-b21j9sf3 170 14 of of IN cord-292559-b21j9sf3 170 15 callous callous JJ cord-292559-b21j9sf3 170 16 - - HYPH cord-292559-b21j9sf3 170 17 unemotional unemotional JJ cord-292559-b21j9sf3 170 18 traits trait NNS cord-292559-b21j9sf3 170 19 [ [ -LRB- cord-292559-b21j9sf3 170 20 40 40 CD cord-292559-b21j9sf3 170 21 ] ] -RRB- cord-292559-b21j9sf3 170 22 , , , cord-292559-b21j9sf3 170 23 finding find VBG cord-292559-b21j9sf3 170 24 evidence evidence NN cord-292559-b21j9sf3 170 25 for for IN cord-292559-b21j9sf3 170 26 good good JJ cord-292559-b21j9sf3 170 27 psychometric psychometric JJ cord-292559-b21j9sf3 170 28 properties property NNS cord-292559-b21j9sf3 170 29 , , , cord-292559-b21j9sf3 170 30 including include VBG cord-292559-b21j9sf3 170 31 measurement measurement NN cord-292559-b21j9sf3 170 32 invariance invariance NN cord-292559-b21j9sf3 170 33 across across IN cord-292559-b21j9sf3 170 34 age age NN cord-292559-b21j9sf3 170 35 , , , cord-292559-b21j9sf3 170 36 sex sex NN cord-292559-b21j9sf3 170 37 , , , cord-292559-b21j9sf3 170 38 and and CC cord-292559-b21j9sf3 170 39 race race NN cord-292559-b21j9sf3 170 40 , , , cord-292559-b21j9sf3 170 41 and and CC cord-292559-b21j9sf3 170 42 expected expect VBN cord-292559-b21j9sf3 170 43 associations association NNS cord-292559-b21j9sf3 170 44 with with IN cord-292559-b21j9sf3 170 45 related related JJ cord-292559-b21j9sf3 170 46 constructs construct NNS cord-292559-b21j9sf3 170 47 such such JJ cord-292559-b21j9sf3 170 48 as as IN cord-292559-b21j9sf3 170 49 conduct conduct NN cord-292559-b21j9sf3 170 50 problems problem NNS cord-292559-b21j9sf3 170 51 , , , cord-292559-b21j9sf3 170 52 attention attention NN cord-292559-b21j9sf3 170 53 deficit deficit NN cord-292559-b21j9sf3 170 54 and and CC cord-292559-b21j9sf3 170 55 hyperactivity hyperactivity NN cord-292559-b21j9sf3 170 56 disorder disorder NN cord-292559-b21j9sf3 170 57 symptoms symptom NNS cord-292559-b21j9sf3 170 58 , , , cord-292559-b21j9sf3 170 59 and and CC cord-292559-b21j9sf3 170 60 oppositional oppositional JJ cord-292559-b21j9sf3 170 61 defiant defiant JJ cord-292559-b21j9sf3 170 62 disorder disorder NN cord-292559-b21j9sf3 170 63 symptoms symptom NNS cord-292559-b21j9sf3 170 64 . . . cord-292559-b21j9sf3 171 1 Importantly importantly RB cord-292559-b21j9sf3 171 2 , , , cord-292559-b21j9sf3 171 3 these these DT cord-292559-b21j9sf3 171 4 findings finding NNS cord-292559-b21j9sf3 171 5 replicated replicate VBD cord-292559-b21j9sf3 171 6 in in IN cord-292559-b21j9sf3 171 7 an an DT cord-292559-b21j9sf3 171 8 independent independent JJ cord-292559-b21j9sf3 171 9 sample sample NN cord-292559-b21j9sf3 171 10 . . . cord-292559-b21j9sf3 172 1 These these DT cord-292559-b21j9sf3 172 2 studies study NNS cord-292559-b21j9sf3 172 3 provide provide VBP cord-292559-b21j9sf3 172 4 important important JJ cord-292559-b21j9sf3 172 5 evidence evidence NN cord-292559-b21j9sf3 172 6 that that IN cord-292559-b21j9sf3 172 7 the the DT cord-292559-b21j9sf3 172 8 ABCD ABCD NNP cord-292559-b21j9sf3 172 9 Study Study NNP cord-292559-b21j9sf3 172 10 sample sample NN cord-292559-b21j9sf3 172 11 can can MD cord-292559-b21j9sf3 172 12 be be VB cord-292559-b21j9sf3 172 13 leveraged leverage VBN cord-292559-b21j9sf3 172 14 to to TO cord-292559-b21j9sf3 172 15 conduct conduct VB cord-292559-b21j9sf3 172 16 rigorous rigorous JJ cord-292559-b21j9sf3 172 17 research research NN cord-292559-b21j9sf3 172 18 practices practice NNS cord-292559-b21j9sf3 172 19 , , , cord-292559-b21j9sf3 172 20 including include VBG cord-292559-b21j9sf3 172 21 examining examine VBG cord-292559-b21j9sf3 172 22 the the DT cord-292559-b21j9sf3 172 23 psychometric psychometric JJ cord-292559-b21j9sf3 172 24 evidence evidence NN cord-292559-b21j9sf3 172 25 for for IN cord-292559-b21j9sf3 172 26 using use VBG cord-292559-b21j9sf3 172 27 existing exist VBG cord-292559-b21j9sf3 172 28 ( ( -LRB- cord-292559-b21j9sf3 172 29 or or CC cord-292559-b21j9sf3 172 30 newly newly RB cord-292559-b21j9sf3 172 31 created create VBN cord-292559-b21j9sf3 172 32 ) ) -RRB- cord-292559-b21j9sf3 172 33 measures measure NNS cord-292559-b21j9sf3 172 34 in in IN cord-292559-b21j9sf3 172 35 a a DT cord-292559-b21j9sf3 172 36 middle middle JJ cord-292559-b21j9sf3 172 37 childhood childhood NN cord-292559-b21j9sf3 172 38 sample sample NN cord-292559-b21j9sf3 172 39 , , , cord-292559-b21j9sf3 172 40 supporting support VBG cord-292559-b21j9sf3 172 41 the the DT cord-292559-b21j9sf3 172 42 use use NN cord-292559-b21j9sf3 172 43 of of IN cord-292559-b21j9sf3 172 44 these these DT cord-292559-b21j9sf3 172 45 measures measure NNS cord-292559-b21j9sf3 172 46 to to TO cord-292559-b21j9sf3 172 47 better better RB cord-292559-b21j9sf3 172 48 understand understand VB cord-292559-b21j9sf3 172 49 the the DT cord-292559-b21j9sf3 172 50 development development NN cord-292559-b21j9sf3 172 51 of of IN cord-292559-b21j9sf3 172 52 risk risk NN cord-292559-b21j9sf3 172 53 . . . cord-292559-b21j9sf3 173 1 Prevalence prevalence NN cord-292559-b21j9sf3 173 2 and and CC cord-292559-b21j9sf3 173 3 behavioral behavioral JJ cord-292559-b21j9sf3 173 4 correlates correlate NNS cord-292559-b21j9sf3 173 5 of of IN cord-292559-b21j9sf3 173 6 psychopathology psychopathology NN cord-292559-b21j9sf3 173 7 . . . cord-292559-b21j9sf3 174 1 There there EX cord-292559-b21j9sf3 174 2 has have VBZ cord-292559-b21j9sf3 174 3 been be VBN cord-292559-b21j9sf3 174 4 great great JJ cord-292559-b21j9sf3 174 5 interest interest NN cord-292559-b21j9sf3 174 6 in in IN cord-292559-b21j9sf3 174 7 understanding understand VBG cord-292559-b21j9sf3 174 8 the the DT cord-292559-b21j9sf3 174 9 prevalence prevalence NN cord-292559-b21j9sf3 174 10 and and CC cord-292559-b21j9sf3 174 11 correlates correlate NNS cord-292559-b21j9sf3 174 12 of of IN cord-292559-b21j9sf3 174 13 a a DT cord-292559-b21j9sf3 174 14 range range NN cord-292559-b21j9sf3 174 15 of of IN cord-292559-b21j9sf3 174 16 forms form NNS cord-292559-b21j9sf3 174 17 of of IN cord-292559-b21j9sf3 174 18 psychopathology psychopathology NN cord-292559-b21j9sf3 174 19 using use VBG cord-292559-b21j9sf3 174 20 the the DT cord-292559-b21j9sf3 174 21 ABCD ABCD NNP cord-292559-b21j9sf3 174 22 Study Study NNP cord-292559-b21j9sf3 174 23 's 's POS cord-292559-b21j9sf3 174 24 large large JJ cord-292559-b21j9sf3 174 25 - - HYPH cord-292559-b21j9sf3 174 26 scale scale NN cord-292559-b21j9sf3 174 27 population population NN cord-292559-b21j9sf3 174 28 - - HYPH cord-292559-b21j9sf3 174 29 based base VBN cord-292559-b21j9sf3 174 30 data datum NNS cord-292559-b21j9sf3 174 31 . . . cord-292559-b21j9sf3 175 1 Several several JJ cord-292559-b21j9sf3 175 2 emerging emerge VBG cord-292559-b21j9sf3 175 3 studies study NNS cord-292559-b21j9sf3 175 4 have have VBP cord-292559-b21j9sf3 175 5 utilized utilize VBN cord-292559-b21j9sf3 175 6 the the DT cord-292559-b21j9sf3 175 7 ABCD ABCD NNP cord-292559-b21j9sf3 175 8 Study Study NNP cord-292559-b21j9sf3 175 9 data datum NNS cord-292559-b21j9sf3 175 10 to to TO cord-292559-b21j9sf3 175 11 examine examine VB cord-292559-b21j9sf3 175 12 the the DT cord-292559-b21j9sf3 175 13 prevalence prevalence NN cord-292559-b21j9sf3 175 14 of of IN cord-292559-b21j9sf3 175 15 psychopathology psychopathology NN cord-292559-b21j9sf3 175 16 in in IN cord-292559-b21j9sf3 175 17 middle middle JJ cord-292559-b21j9sf3 175 18 childhood childhood NN cord-292559-b21j9sf3 175 19 , , , cord-292559-b21j9sf3 175 20 as as RB cord-292559-b21j9sf3 175 21 well well RB cord-292559-b21j9sf3 175 22 as as IN cord-292559-b21j9sf3 175 23 behavioral behavioral JJ cord-292559-b21j9sf3 175 24 and and CC cord-292559-b21j9sf3 175 25 cognitive cognitive JJ cord-292559-b21j9sf3 175 26 correlates correlate NNS cord-292559-b21j9sf3 175 27 of of IN cord-292559-b21j9sf3 175 28 psychopathology psychopathology NN cord-292559-b21j9sf3 175 29 . . . cord-292559-b21j9sf3 176 1 As as IN cord-292559-b21j9sf3 176 2 previously previously RB cord-292559-b21j9sf3 176 3 mentioned mention VBN cord-292559-b21j9sf3 176 4 , , , cord-292559-b21j9sf3 176 5 one one CD cord-292559-b21j9sf3 176 6 of of IN cord-292559-b21j9sf3 176 7 the the DT cord-292559-b21j9sf3 176 8 first first JJ cord-292559-b21j9sf3 176 9 emerging emerge VBG cord-292559-b21j9sf3 176 10 studies study NNS cord-292559-b21j9sf3 176 11 published publish VBD cord-292559-b21j9sf3 176 12 examining examine VBG cord-292559-b21j9sf3 176 13 ABCD ABCD NNP cord-292559-b21j9sf3 176 14 Study Study NNP cord-292559-b21j9sf3 176 15 baseline baseline JJ cord-292559-b21j9sf3 176 16 data datum NNS cord-292559-b21j9sf3 176 17 examined examine VBD cord-292559-b21j9sf3 176 18 associations association NNS cord-292559-b21j9sf3 176 19 between between IN cord-292559-b21j9sf3 176 20 PLEs ple NNS cord-292559-b21j9sf3 176 21 and and CC cord-292559-b21j9sf3 176 22 correlates correlate NNS cord-292559-b21j9sf3 176 23 of of IN cord-292559-b21j9sf3 176 24 psychosis psychosis NN cord-292559-b21j9sf3 176 25 spectrum spectrum NN cord-292559-b21j9sf3 176 26 symptoms symptom NNS cord-292559-b21j9sf3 176 27 [ [ -LRB- cord-292559-b21j9sf3 176 28 44 44 CD cord-292559-b21j9sf3 176 29 ] ] -RRB- cord-292559-b21j9sf3 176 30 . . . cord-292559-b21j9sf3 177 1 This this DT cord-292559-b21j9sf3 177 2 emerging emerge VBG cord-292559-b21j9sf3 177 3 study study NN cord-292559-b21j9sf3 177 4 found find VBD cord-292559-b21j9sf3 177 5 PLEs ple NNS cord-292559-b21j9sf3 177 6 were be VBD cord-292559-b21j9sf3 177 7 associated associate VBN cord-292559-b21j9sf3 177 8 with with IN cord-292559-b21j9sf3 177 9 several several JJ cord-292559-b21j9sf3 177 10 expected expect VBN cord-292559-b21j9sf3 177 11 associations association NNS cord-292559-b21j9sf3 177 12 , , , cord-292559-b21j9sf3 177 13 such such JJ cord-292559-b21j9sf3 177 14 as as IN cord-292559-b21j9sf3 177 15 cognitive cognitive JJ cord-292559-b21j9sf3 177 16 impairments impairment NNS cord-292559-b21j9sf3 177 17 ( ( -LRB- cord-292559-b21j9sf3 177 18 including include VBG cord-292559-b21j9sf3 177 19 working work VBG cord-292559-b21j9sf3 177 20 memory memory NN cord-292559-b21j9sf3 177 21 impairments impairment NNS cord-292559-b21j9sf3 177 22 ) ) -RRB- cord-292559-b21j9sf3 177 23 , , , cord-292559-b21j9sf3 177 24 motor motor NN cord-292559-b21j9sf3 177 25 and and CC cord-292559-b21j9sf3 177 26 speech speech NN cord-292559-b21j9sf3 177 27 developmental developmental JJ cord-292559-b21j9sf3 177 28 delays delay NNS cord-292559-b21j9sf3 177 29 , , , cord-292559-b21j9sf3 177 30 higher high JJR cord-292559-b21j9sf3 177 31 internalizing internalize VBG cord-292559-b21j9sf3 177 32 and and CC cord-292559-b21j9sf3 177 33 externalizing externalize VBG cord-292559-b21j9sf3 177 34 symptoms symptom NNS cord-292559-b21j9sf3 177 35 , , , cord-292559-b21j9sf3 177 36 greater great JJR cord-292559-b21j9sf3 177 37 family family NN cord-292559-b21j9sf3 177 38 history history NN cord-292559-b21j9sf3 177 39 of of IN cord-292559-b21j9sf3 177 40 psychosis psychosis NN cord-292559-b21j9sf3 177 41 , , , cord-292559-b21j9sf3 177 42 and and CC cord-292559-b21j9sf3 177 43 higher high JJR cord-292559-b21j9sf3 177 44 scores score NNS cord-292559-b21j9sf3 177 45 on on IN cord-292559-b21j9sf3 177 46 other other JJ cord-292559-b21j9sf3 177 47 measures measure NNS cord-292559-b21j9sf3 177 48 of of IN cord-292559-b21j9sf3 177 49 psychosis psychosis NN cord-292559-b21j9sf3 177 50 spectrum spectrum NN cord-292559-b21j9sf3 177 51 symptoms symptom NNS cord-292559-b21j9sf3 177 52 . . . cord-292559-b21j9sf3 178 1 Another another DT cord-292559-b21j9sf3 178 2 emerging emerge VBG cord-292559-b21j9sf3 178 3 study study NN cord-292559-b21j9sf3 178 4 found find VBD cord-292559-b21j9sf3 178 5 maladaptive maladaptive JJ cord-292559-b21j9sf3 178 6 guilt guilt NN cord-292559-b21j9sf3 178 7 was be VBD cord-292559-b21j9sf3 178 8 associated associate VBN cord-292559-b21j9sf3 178 9 with with IN cord-292559-b21j9sf3 178 10 several several JJ cord-292559-b21j9sf3 178 11 expected expect VBN cord-292559-b21j9sf3 178 12 correlates correlate NNS cord-292559-b21j9sf3 178 13 , , , cord-292559-b21j9sf3 178 14 including include VBG cord-292559-b21j9sf3 178 15 family family NN cord-292559-b21j9sf3 178 16 SES SES NNP cord-292559-b21j9sf3 178 17 , , , cord-292559-b21j9sf3 178 18 youth youth NN cord-292559-b21j9sf3 178 19 - - HYPH cord-292559-b21j9sf3 178 20 reported report VBN cord-292559-b21j9sf3 178 21 family family NN cord-292559-b21j9sf3 178 22 conflict conflict NN cord-292559-b21j9sf3 178 23 , , , cord-292559-b21j9sf3 178 24 history history NN cord-292559-b21j9sf3 178 25 of of IN cord-292559-b21j9sf3 178 26 maternal maternal JJ cord-292559-b21j9sf3 178 27 depression depression NN cord-292559-b21j9sf3 178 28 , , , cord-292559-b21j9sf3 178 29 and and CC cord-292559-b21j9sf3 178 30 parental parental JJ cord-292559-b21j9sf3 178 31 rejection rejection NN cord-292559-b21j9sf3 178 32 [ [ -LRB- cord-292559-b21j9sf3 178 33 46 46 CD cord-292559-b21j9sf3 178 34 ] ] -RRB- cord-292559-b21j9sf3 178 35 . . . cord-292559-b21j9sf3 179 1 Emerging emerge VBG cord-292559-b21j9sf3 179 2 research research NN cord-292559-b21j9sf3 179 3 also also RB cord-292559-b21j9sf3 179 4 examined examine VBD cord-292559-b21j9sf3 179 5 prevalence prevalence NN cord-292559-b21j9sf3 179 6 of of IN cord-292559-b21j9sf3 179 7 eating eat VBG cord-292559-b21j9sf3 179 8 disorder disorder NN cord-292559-b21j9sf3 179 9 diagnoses diagnosis NNS cord-292559-b21j9sf3 179 10 in in IN cord-292559-b21j9sf3 179 11 middle middle JJ cord-292559-b21j9sf3 179 12 childhood childhood NN cord-292559-b21j9sf3 179 13 [ [ -LRB- cord-292559-b21j9sf3 179 14 47 47 CD cord-292559-b21j9sf3 179 15 ] ] -RRB- cord-292559-b21j9sf3 179 16 , , , cord-292559-b21j9sf3 179 17 finding find VBG cord-292559-b21j9sf3 179 18 the the DT cord-292559-b21j9sf3 179 19 prevalence prevalence NN cord-292559-b21j9sf3 179 20 of of IN cord-292559-b21j9sf3 179 21 overall overall JJ cord-292559-b21j9sf3 179 22 eating eat VBG cord-292559-b21j9sf3 179 23 disorder disorder NN cord-292559-b21j9sf3 179 24 diagnoses diagnosis NNS cord-292559-b21j9sf3 179 25 was be VBD cord-292559-b21j9sf3 179 26 1.4 1.4 CD cord-292559-b21j9sf3 179 27 % % NN cord-292559-b21j9sf3 179 28 , , , cord-292559-b21j9sf3 179 29 and and CC cord-292559-b21j9sf3 179 30 the the DT cord-292559-b21j9sf3 179 31 prevalence prevalence NN cord-292559-b21j9sf3 179 32 of of IN cord-292559-b21j9sf3 179 33 anorexia anorexia NN cord-292559-b21j9sf3 179 34 nervosa nervosa NN cord-292559-b21j9sf3 179 35 diagnoses diagnosis NNS cord-292559-b21j9sf3 179 36 was be VBD cord-292559-b21j9sf3 179 37 0.1 0.1 CD cord-292559-b21j9sf3 179 38 % % NN cord-292559-b21j9sf3 179 39 . . . cord-292559-b21j9sf3 180 1 Lastly lastly RB cord-292559-b21j9sf3 180 2 , , , cord-292559-b21j9sf3 180 3 an an DT cord-292559-b21j9sf3 180 4 emerging emerge VBG cord-292559-b21j9sf3 180 5 study study NN cord-292559-b21j9sf3 180 6 examined examine VBD cord-292559-b21j9sf3 180 7 the the DT cord-292559-b21j9sf3 180 8 prevalence prevalence NN cord-292559-b21j9sf3 180 9 and and CC cord-292559-b21j9sf3 180 10 associations association NNS cord-292559-b21j9sf3 180 11 with with IN cord-292559-b21j9sf3 180 12 suicidality suicidality NN cord-292559-b21j9sf3 180 13 in in IN cord-292559-b21j9sf3 180 14 middle middle JJ cord-292559-b21j9sf3 180 15 childhood childhood NN cord-292559-b21j9sf3 180 16 [ [ -LRB- cord-292559-b21j9sf3 180 17 48 48 CD cord-292559-b21j9sf3 180 18 ] ] -RRB- cord-292559-b21j9sf3 180 19 , , , cord-292559-b21j9sf3 180 20 finding find VBG cord-292559-b21j9sf3 180 21 the the DT cord-292559-b21j9sf3 180 22 prevalence prevalence NN cord-292559-b21j9sf3 180 23 of of IN cord-292559-b21j9sf3 180 24 passive passive JJ cord-292559-b21j9sf3 180 25 suicidal suicidal JJ cord-292559-b21j9sf3 180 26 ideation ideation NN cord-292559-b21j9sf3 180 27 ( ( -LRB- cord-292559-b21j9sf3 180 28 as as IN cord-292559-b21j9sf3 180 29 reported report VBN cord-292559-b21j9sf3 180 30 by by IN cord-292559-b21j9sf3 180 31 youth youth NN cord-292559-b21j9sf3 180 32 or or CC cord-292559-b21j9sf3 180 33 parent parent NN cord-292559-b21j9sf3 180 34 ) ) -RRB- cord-292559-b21j9sf3 180 35 was be VBD cord-292559-b21j9sf3 180 36 6.4 6.4 CD cord-292559-b21j9sf3 180 37 % % NN cord-292559-b21j9sf3 180 38 , , , cord-292559-b21j9sf3 180 39 active active JJ cord-292559-b21j9sf3 180 40 suicidal suicidal JJ cord-292559-b21j9sf3 180 41 ideation ideation NN cord-292559-b21j9sf3 180 42 ( ( -LRB- cord-292559-b21j9sf3 180 43 either either CC cord-292559-b21j9sf3 180 44 non non JJ cord-292559-b21j9sf3 180 45 - - JJ cord-292559-b21j9sf3 180 46 specific specific JJ cord-292559-b21j9sf3 180 47 or or CC cord-292559-b21j9sf3 180 48 specific specific JJ cord-292559-b21j9sf3 180 49 ) ) -RRB- cord-292559-b21j9sf3 180 50 was be VBD cord-292559-b21j9sf3 180 51 6.8 6.8 CD cord-292559-b21j9sf3 180 52 % % NN cord-292559-b21j9sf3 180 53 , , , cord-292559-b21j9sf3 180 54 and and CC cord-292559-b21j9sf3 180 55 suicide suicide NN cord-292559-b21j9sf3 180 56 attempts attempt NNS cord-292559-b21j9sf3 180 57 were~1.3 were~1.3 WDT cord-292559-b21j9sf3 180 58 % % NN cord-292559-b21j9sf3 180 59 . . . cord-292559-b21j9sf3 181 1 Further further RB cord-292559-b21j9sf3 181 2 , , , cord-292559-b21j9sf3 181 3 the the DT cord-292559-b21j9sf3 181 4 prevalence prevalence NN cord-292559-b21j9sf3 181 5 of of IN cord-292559-b21j9sf3 181 6 non non JJ cord-292559-b21j9sf3 181 7 - - JJ cord-292559-b21j9sf3 181 8 suicidal suicidal JJ cord-292559-b21j9sf3 181 9 self self NN cord-292559-b21j9sf3 181 10 - - HYPH cord-292559-b21j9sf3 181 11 injury injury NN cord-292559-b21j9sf3 181 12 was~9.1 was~9.1 IN cord-292559-b21j9sf3 181 13 % % NN cord-292559-b21j9sf3 181 14 . . . cord-292559-b21j9sf3 182 1 Low low JJ cord-292559-b21j9sf3 182 2 parental parental JJ cord-292559-b21j9sf3 182 3 monitoring monitoring NN cord-292559-b21j9sf3 182 4 was be VBD cord-292559-b21j9sf3 182 5 associated associate VBN cord-292559-b21j9sf3 182 6 with with IN cord-292559-b21j9sf3 182 7 suicidal suicidal JJ cord-292559-b21j9sf3 182 8 ideation ideation NN cord-292559-b21j9sf3 182 9 , , , cord-292559-b21j9sf3 182 10 suicide suicide NN cord-292559-b21j9sf3 182 11 attempt attempt NN cord-292559-b21j9sf3 182 12 , , , cord-292559-b21j9sf3 182 13 and and CC cord-292559-b21j9sf3 182 14 nonsuicidal nonsuicidal NNP cord-292559-b21j9sf3 182 15 self self NN cord-292559-b21j9sf3 182 16 - - HYPH cord-292559-b21j9sf3 182 17 injury injury NN cord-292559-b21j9sf3 182 18 , , , cord-292559-b21j9sf3 182 19 and and CC cord-292559-b21j9sf3 182 20 as as IN cord-292559-b21j9sf3 182 21 with with IN cord-292559-b21j9sf3 182 22 maladaptive maladaptive JJ cord-292559-b21j9sf3 182 23 guilt guilt NN cord-292559-b21j9sf3 182 24 , , , cord-292559-b21j9sf3 182 25 family family NN cord-292559-b21j9sf3 182 26 conflict conflict NN cord-292559-b21j9sf3 182 27 was be VBD cord-292559-b21j9sf3 182 28 associated associate VBN cord-292559-b21j9sf3 182 29 with with IN cord-292559-b21j9sf3 182 30 suicidal suicidal JJ cord-292559-b21j9sf3 182 31 ideation ideation NN cord-292559-b21j9sf3 182 32 and and CC cord-292559-b21j9sf3 182 33 non non JJ cord-292559-b21j9sf3 182 34 - - JJ cord-292559-b21j9sf3 182 35 suicidal suicidal JJ cord-292559-b21j9sf3 182 36 self self NN cord-292559-b21j9sf3 182 37 - - HYPH cord-292559-b21j9sf3 182 38 injury injury NN cord-292559-b21j9sf3 182 39 . . . cord-292559-b21j9sf3 183 1 Importantly importantly RB cord-292559-b21j9sf3 183 2 , , , cord-292559-b21j9sf3 183 3 the the DT cord-292559-b21j9sf3 183 4 authors author NNS cord-292559-b21j9sf3 183 5 replicated replicate VBD cord-292559-b21j9sf3 183 6 these these DT cord-292559-b21j9sf3 183 7 findings finding NNS cord-292559-b21j9sf3 183 8 in in IN cord-292559-b21j9sf3 183 9 a a DT cord-292559-b21j9sf3 183 10 hold hold VB cord-292559-b21j9sf3 183 11 - - HYPH cord-292559-b21j9sf3 183 12 out out NN cord-292559-b21j9sf3 183 13 ABCD ABCD NNP cord-292559-b21j9sf3 183 14 Study Study NNP cord-292559-b21j9sf3 183 15 baseline baseline JJ cord-292559-b21j9sf3 183 16 sample sample NN cord-292559-b21j9sf3 183 17 ( ( -LRB- cord-292559-b21j9sf3 183 18 i.e. i.e. FW cord-292559-b21j9sf3 183 19 , , , cord-292559-b21j9sf3 183 20 30 30 CD cord-292559-b21j9sf3 183 21 % % NN cord-292559-b21j9sf3 183 22 of of IN cord-292559-b21j9sf3 183 23 the the DT cord-292559-b21j9sf3 183 24 baseline baseline JJ cord-292559-b21j9sf3 183 25 sample sample NN cord-292559-b21j9sf3 183 26 ) ) -RRB- cord-292559-b21j9sf3 183 27 . . . cord-292559-b21j9sf3 184 1 Together together RB cord-292559-b21j9sf3 184 2 these these DT cord-292559-b21j9sf3 184 3 emerging emerge VBG cord-292559-b21j9sf3 184 4 studies study NNS cord-292559-b21j9sf3 184 5 are be VBP cord-292559-b21j9sf3 184 6 beginning begin VBG cord-292559-b21j9sf3 184 7 to to TO cord-292559-b21j9sf3 184 8 provide provide VB cord-292559-b21j9sf3 184 9 an an DT cord-292559-b21j9sf3 184 10 important important JJ cord-292559-b21j9sf3 184 11 additional additional JJ cord-292559-b21j9sf3 184 12 information information NN cord-292559-b21j9sf3 184 13 on on IN cord-292559-b21j9sf3 184 14 the the DT cord-292559-b21j9sf3 184 15 prevalence prevalence NN cord-292559-b21j9sf3 184 16 of of IN cord-292559-b21j9sf3 184 17 various various JJ cord-292559-b21j9sf3 184 18 forms form NNS cord-292559-b21j9sf3 184 19 of of IN cord-292559-b21j9sf3 184 20 psychopathology psychopathology NN cord-292559-b21j9sf3 184 21 in in IN cord-292559-b21j9sf3 184 22 a a DT cord-292559-b21j9sf3 184 23 middle middle JJ cord-292559-b21j9sf3 184 24 childhood childhood NN cord-292559-b21j9sf3 184 25 sample sample NN cord-292559-b21j9sf3 184 26 , , , cord-292559-b21j9sf3 184 27 complementing complement VBG cord-292559-b21j9sf3 184 28 the the DT cord-292559-b21j9sf3 184 29 already already RB cord-292559-b21j9sf3 184 30 existing exist VBG cord-292559-b21j9sf3 184 31 epidemiological epidemiological JJ cord-292559-b21j9sf3 184 32 data datum NNS cord-292559-b21j9sf3 184 33 that that WDT cord-292559-b21j9sf3 184 34 is be VBZ cord-292559-b21j9sf3 184 35 more more RBR cord-292559-b21j9sf3 184 36 common common JJ cord-292559-b21j9sf3 184 37 in in IN cord-292559-b21j9sf3 184 38 adolescence adolescence NN cord-292559-b21j9sf3 184 39 and and CC cord-292559-b21j9sf3 184 40 adulthood adulthood NN cord-292559-b21j9sf3 184 41 . . . cord-292559-b21j9sf3 185 1 In in IN cord-292559-b21j9sf3 185 2 particular particular JJ cord-292559-b21j9sf3 185 3 , , , cord-292559-b21j9sf3 185 4 this this DT cord-292559-b21j9sf3 185 5 novel novel JJ cord-292559-b21j9sf3 185 6 data datum NNS cord-292559-b21j9sf3 185 7 on on IN cord-292559-b21j9sf3 185 8 rates rate NNS cord-292559-b21j9sf3 185 9 of of IN cord-292559-b21j9sf3 185 10 suicidal suicidal JJ cord-292559-b21j9sf3 185 11 ideation ideation NN cord-292559-b21j9sf3 185 12 and and CC cord-292559-b21j9sf3 185 13 attempts attempt NNS cord-292559-b21j9sf3 185 14 starting start VBG cord-292559-b21j9sf3 185 15 in in IN cord-292559-b21j9sf3 185 16 middle middle JJ cord-292559-b21j9sf3 185 17 childhood childhood NN cord-292559-b21j9sf3 185 18 is be VBZ cord-292559-b21j9sf3 185 19 critically critically RB cord-292559-b21j9sf3 185 20 informative informative JJ cord-292559-b21j9sf3 185 21 about about IN cord-292559-b21j9sf3 185 22 the the DT cord-292559-b21j9sf3 185 23 timing timing NN cord-292559-b21j9sf3 185 24 of of IN cord-292559-b21j9sf3 185 25 emergence emergence NN cord-292559-b21j9sf3 185 26 of of IN cord-292559-b21j9sf3 185 27 such such JJ cord-292559-b21j9sf3 185 28 thoughts thought NNS cord-292559-b21j9sf3 185 29 and and CC cord-292559-b21j9sf3 185 30 behavior behavior NN cord-292559-b21j9sf3 185 31 in in IN cord-292559-b21j9sf3 185 32 relationship relationship NN cord-292559-b21j9sf3 185 33 to to IN cord-292559-b21j9sf3 185 34 the the DT cord-292559-b21j9sf3 185 35 rates rate NNS cord-292559-b21j9sf3 185 36 in in IN cord-292559-b21j9sf3 185 37 adolescence adolescence NN cord-292559-b21j9sf3 185 38 already already RB cord-292559-b21j9sf3 185 39 identified identify VBN cord-292559-b21j9sf3 185 40 by by IN cord-292559-b21j9sf3 185 41 the the DT cord-292559-b21j9sf3 185 42 Centers Centers NNPS cord-292559-b21j9sf3 185 43 for for IN cord-292559-b21j9sf3 185 44 Disease Disease NNP cord-292559-b21j9sf3 185 45 Control Control NNP cord-292559-b21j9sf3 185 46 and and CC cord-292559-b21j9sf3 185 47 Prevention Prevention NNP cord-292559-b21j9sf3 185 48 . . . cord-292559-b21j9sf3 186 1 Associations association NNS cord-292559-b21j9sf3 186 2 between between IN cord-292559-b21j9sf3 186 3 psychopathology psychopathology NN cord-292559-b21j9sf3 186 4 and and CC cord-292559-b21j9sf3 186 5 both both DT cord-292559-b21j9sf3 186 6 physical physical JJ cord-292559-b21j9sf3 186 7 health health NN cord-292559-b21j9sf3 186 8 and and CC cord-292559-b21j9sf3 186 9 the the DT cord-292559-b21j9sf3 186 10 environment environment NN cord-292559-b21j9sf3 186 11 . . . cord-292559-b21j9sf3 187 1 In in IN cord-292559-b21j9sf3 187 2 addition addition NN cord-292559-b21j9sf3 187 3 to to IN cord-292559-b21j9sf3 187 4 examining examine VBG cord-292559-b21j9sf3 187 5 prevalence prevalence NN cord-292559-b21j9sf3 187 6 and and CC cord-292559-b21j9sf3 187 7 behavioral behavioral JJ cord-292559-b21j9sf3 187 8 correlates correlate NNS cord-292559-b21j9sf3 187 9 , , , cord-292559-b21j9sf3 187 10 the the DT cord-292559-b21j9sf3 187 11 ABCD ABCD NNP cord-292559-b21j9sf3 187 12 Study Study NNP cord-292559-b21j9sf3 187 13 baseline baseline JJ cord-292559-b21j9sf3 187 14 sample sample NN cord-292559-b21j9sf3 187 15 has have VBZ cord-292559-b21j9sf3 187 16 also also RB cord-292559-b21j9sf3 187 17 been be VBN cord-292559-b21j9sf3 187 18 utilized utilize VBN cord-292559-b21j9sf3 187 19 to to TO cord-292559-b21j9sf3 187 20 assess assess VB cord-292559-b21j9sf3 187 21 associations association NNS cord-292559-b21j9sf3 187 22 between between IN cord-292559-b21j9sf3 187 23 psychopathology psychopathology NN cord-292559-b21j9sf3 187 24 and and CC cord-292559-b21j9sf3 187 25 several several JJ cord-292559-b21j9sf3 187 26 environmental environmental JJ cord-292559-b21j9sf3 187 27 and and CC cord-292559-b21j9sf3 187 28 health health NN cord-292559-b21j9sf3 187 29 - - HYPH cord-292559-b21j9sf3 187 30 related relate VBN cord-292559-b21j9sf3 187 31 variables variable NNS cord-292559-b21j9sf3 187 32 . . . cord-292559-b21j9sf3 188 1 These these DT cord-292559-b21j9sf3 188 2 emerging emerge VBG cord-292559-b21j9sf3 188 3 studies study NNS cord-292559-b21j9sf3 188 4 point point VBP cord-292559-b21j9sf3 188 5 to to IN cord-292559-b21j9sf3 188 6 several several JJ cord-292559-b21j9sf3 188 7 factors factor NNS cord-292559-b21j9sf3 188 8 , , , cord-292559-b21j9sf3 188 9 including include VBG cord-292559-b21j9sf3 188 10 prenatal prenatal JJ cord-292559-b21j9sf3 188 11 drug drug NN cord-292559-b21j9sf3 188 12 use use NN cord-292559-b21j9sf3 188 13 , , , cord-292559-b21j9sf3 188 14 body body NN cord-292559-b21j9sf3 188 15 mass mass NN cord-292559-b21j9sf3 188 16 index index NN cord-292559-b21j9sf3 188 17 ( ( -LRB- cord-292559-b21j9sf3 188 18 BMI BMI NNP cord-292559-b21j9sf3 188 19 ) ) -RRB- cord-292559-b21j9sf3 188 20 , , , cord-292559-b21j9sf3 188 21 and and CC cord-292559-b21j9sf3 188 22 cognition cognition NN cord-292559-b21j9sf3 188 23 already already RB cord-292559-b21j9sf3 188 24 showing show VBG cord-292559-b21j9sf3 188 25 associations association NNS cord-292559-b21j9sf3 188 26 with with IN cord-292559-b21j9sf3 188 27 psychopathology psychopathology NN cord-292559-b21j9sf3 188 28 and and CC cord-292559-b21j9sf3 188 29 other other JJ cord-292559-b21j9sf3 188 30 health health NN cord-292559-b21j9sf3 188 31 - - HYPH cord-292559-b21j9sf3 188 32 relevant relevant JJ cord-292559-b21j9sf3 188 33 variables variable NNS cord-292559-b21j9sf3 188 34 in in IN cord-292559-b21j9sf3 188 35 middle middle JJ cord-292559-b21j9sf3 188 36 childhood childhood NN cord-292559-b21j9sf3 188 37 . . . cord-292559-b21j9sf3 189 1 Emerging emerge VBG cord-292559-b21j9sf3 189 2 work work NN cord-292559-b21j9sf3 189 3 indicates indicate VBZ cord-292559-b21j9sf3 189 4 that that IN cord-292559-b21j9sf3 189 5 prenatal prenatal JJ cord-292559-b21j9sf3 189 6 cannabis cannabis NN cord-292559-b21j9sf3 189 7 exposure exposure NN cord-292559-b21j9sf3 189 8 after after IN cord-292559-b21j9sf3 189 9 knowledge knowledge NN cord-292559-b21j9sf3 189 10 of of IN cord-292559-b21j9sf3 189 11 pregnancy pregnancy NN cord-292559-b21j9sf3 189 12 is be VBZ cord-292559-b21j9sf3 189 13 associated associate VBN cord-292559-b21j9sf3 189 14 with with IN cord-292559-b21j9sf3 189 15 PLEs ple NNS cord-292559-b21j9sf3 189 16 , , , cord-292559-b21j9sf3 189 17 but but CC cord-292559-b21j9sf3 189 18 not not RB cord-292559-b21j9sf3 189 19 internalizing internalize VBG cord-292559-b21j9sf3 189 20 , , , cord-292559-b21j9sf3 189 21 externalizing externalize VBG cord-292559-b21j9sf3 189 22 , , , cord-292559-b21j9sf3 189 23 or or CC cord-292559-b21j9sf3 189 24 attention attention NN cord-292559-b21j9sf3 189 25 symptoms symptom NNS cord-292559-b21j9sf3 189 26 [ [ -LRB- cord-292559-b21j9sf3 189 27 49 49 CD cord-292559-b21j9sf3 189 28 ] ] -RRB- cord-292559-b21j9sf3 189 29 . . . cord-292559-b21j9sf3 190 1 Another another DT cord-292559-b21j9sf3 190 2 emerging emerge VBG cord-292559-b21j9sf3 190 3 study study NN cord-292559-b21j9sf3 190 4 examined examine VBD cord-292559-b21j9sf3 190 5 associations association NNS cord-292559-b21j9sf3 190 6 between between IN cord-292559-b21j9sf3 190 7 health health NN cord-292559-b21j9sf3 190 8 and and CC cord-292559-b21j9sf3 190 9 environment environment NN cord-292559-b21j9sf3 190 10 , , , cord-292559-b21j9sf3 190 11 including include VBG cord-292559-b21j9sf3 190 12 correlates correlate NNS cord-292559-b21j9sf3 190 13 of of IN cord-292559-b21j9sf3 190 14 BMI BMI NNP cord-292559-b21j9sf3 190 15 in in IN cord-292559-b21j9sf3 190 16 middle middle JJ cord-292559-b21j9sf3 190 17 childhood childhood NN cord-292559-b21j9sf3 190 18 [ [ -LRB- cord-292559-b21j9sf3 190 19 50 50 CD cord-292559-b21j9sf3 190 20 ] ] -RRB- cord-292559-b21j9sf3 190 21 , , , cord-292559-b21j9sf3 190 22 finding find VBG cord-292559-b21j9sf3 190 23 attention attention NN cord-292559-b21j9sf3 190 24 problems problem NNS cord-292559-b21j9sf3 190 25 , , , cord-292559-b21j9sf3 190 26 social social JJ cord-292559-b21j9sf3 190 27 problems problem NNS cord-292559-b21j9sf3 190 28 , , , cord-292559-b21j9sf3 190 29 and and CC cord-292559-b21j9sf3 190 30 screen screen NN cord-292559-b21j9sf3 190 31 time time NN cord-292559-b21j9sf3 190 32 were be VBD cord-292559-b21j9sf3 190 33 all all DT cord-292559-b21j9sf3 190 34 associated associate VBN cord-292559-b21j9sf3 190 35 with with IN cord-292559-b21j9sf3 190 36 higher high JJR cord-292559-b21j9sf3 190 37 BMI BMI NNP cord-292559-b21j9sf3 190 38 , , , cord-292559-b21j9sf3 190 39 with with IN cord-292559-b21j9sf3 190 40 some some DT cord-292559-b21j9sf3 190 41 evidence evidence NN cord-292559-b21j9sf3 190 42 that that IN cord-292559-b21j9sf3 190 43 demographic demographic JJ cord-292559-b21j9sf3 190 44 factors factor NNS cord-292559-b21j9sf3 190 45 ( ( -LRB- cord-292559-b21j9sf3 190 46 e.g. e.g. RB cord-292559-b21j9sf3 190 47 , , , cord-292559-b21j9sf3 190 48 Hispanic hispanic JJ cord-292559-b21j9sf3 190 49 ethnicity ethnicity NN cord-292559-b21j9sf3 190 50 , , , cord-292559-b21j9sf3 190 51 lower low JJR cord-292559-b21j9sf3 190 52 income income NN cord-292559-b21j9sf3 190 53 ) ) -RRB- cord-292559-b21j9sf3 190 54 were be VBD cord-292559-b21j9sf3 190 55 most most RBS cord-292559-b21j9sf3 190 56 strongly strongly RB cord-292559-b21j9sf3 190 57 associated associate VBN cord-292559-b21j9sf3 190 58 with with IN cord-292559-b21j9sf3 190 59 greater great JJR cord-292559-b21j9sf3 190 60 BMI BMI NNP cord-292559-b21j9sf3 190 61 . . . cord-292559-b21j9sf3 191 1 Other other JJ cord-292559-b21j9sf3 191 2 emerging emerge VBG cord-292559-b21j9sf3 191 3 research research NN cord-292559-b21j9sf3 191 4 examined examine VBD cord-292559-b21j9sf3 191 5 associations association NNS cord-292559-b21j9sf3 191 6 with with IN cord-292559-b21j9sf3 191 7 sexual sexual JJ cord-292559-b21j9sf3 191 8 orientation orientation NN cord-292559-b21j9sf3 191 9 and/or and/or CC cord-292559-b21j9sf3 191 10 gender gender NN cord-292559-b21j9sf3 191 11 identity identity NN cord-292559-b21j9sf3 191 12 status status NN cord-292559-b21j9sf3 191 13 [ [ -LRB- cord-292559-b21j9sf3 191 14 51 51 CD cord-292559-b21j9sf3 191 15 ] ] -RRB- cord-292559-b21j9sf3 191 16 , , , cord-292559-b21j9sf3 191 17 finding find VBG cord-292559-b21j9sf3 191 18 that that IN cord-292559-b21j9sf3 191 19 less less JJR cord-292559-b21j9sf3 191 20 than than IN cord-292559-b21j9sf3 191 21 1 1 CD cord-292559-b21j9sf3 191 22 % % NN cord-292559-b21j9sf3 191 23 of of IN cord-292559-b21j9sf3 191 24 the the DT cord-292559-b21j9sf3 191 25 sample sample NN cord-292559-b21j9sf3 191 26 identifies identify VBZ cord-292559-b21j9sf3 191 27 as as IN cord-292559-b21j9sf3 191 28 a a DT cord-292559-b21j9sf3 191 29 sexual sexual JJ cord-292559-b21j9sf3 191 30 orientation orientation NN cord-292559-b21j9sf3 191 31 or or CC cord-292559-b21j9sf3 191 32 gender gender NN cord-292559-b21j9sf3 191 33 identity identity NN cord-292559-b21j9sf3 191 34 minority minority NN cord-292559-b21j9sf3 191 35 , , , cord-292559-b21j9sf3 191 36 and and CC cord-292559-b21j9sf3 191 37 that that IN cord-292559-b21j9sf3 191 38 minority minority NN cord-292559-b21j9sf3 191 39 status status NN cord-292559-b21j9sf3 191 40 was be VBD cord-292559-b21j9sf3 191 41 not not RB cord-292559-b21j9sf3 191 42 a a DT cord-292559-b21j9sf3 191 43 source source NN cord-292559-b21j9sf3 191 44 of of IN cord-292559-b21j9sf3 191 45 substantial substantial JJ cord-292559-b21j9sf3 191 46 family family NN cord-292559-b21j9sf3 191 47 or or CC cord-292559-b21j9sf3 191 48 school school NN cord-292559-b21j9sf3 191 49 problems problem NNS cord-292559-b21j9sf3 191 50 . . . cord-292559-b21j9sf3 192 1 However however RB cord-292559-b21j9sf3 192 2 , , , cord-292559-b21j9sf3 192 3 further further RB cord-292559-b21j9sf3 192 4 emerging emerge VBG cord-292559-b21j9sf3 192 5 research research NN cord-292559-b21j9sf3 192 6 did do VBD cord-292559-b21j9sf3 192 7 show show VB cord-292559-b21j9sf3 192 8 that that IN cord-292559-b21j9sf3 192 9 sexual sexual JJ cord-292559-b21j9sf3 192 10 orientation orientation NN cord-292559-b21j9sf3 192 11 minority minority NN cord-292559-b21j9sf3 192 12 status status NN cord-292559-b21j9sf3 192 13 was be VBD cord-292559-b21j9sf3 192 14 associated associate VBN cord-292559-b21j9sf3 192 15 with with IN cord-292559-b21j9sf3 192 16 greater great JJR cord-292559-b21j9sf3 192 17 prevalence prevalence NN cord-292559-b21j9sf3 192 18 of of IN cord-292559-b21j9sf3 192 19 mood mood NN cord-292559-b21j9sf3 192 20 disorders disorder NNS cord-292559-b21j9sf3 192 21 and and CC cord-292559-b21j9sf3 192 22 suicidality suicidality NN cord-292559-b21j9sf3 192 23 than than IN cord-292559-b21j9sf3 192 24 in in IN cord-292559-b21j9sf3 192 25 heterosexual heterosexual JJ cord-292559-b21j9sf3 192 26 - - HYPH cord-292559-b21j9sf3 192 27 identifying identify VBG cord-292559-b21j9sf3 192 28 youth youth NN cord-292559-b21j9sf3 192 29 [ [ -LRB- cord-292559-b21j9sf3 192 30 52 52 CD cord-292559-b21j9sf3 192 31 ] ] -RRB- cord-292559-b21j9sf3 192 32 . . . cord-292559-b21j9sf3 193 1 Another another DT cord-292559-b21j9sf3 193 2 emerging emerge VBG cord-292559-b21j9sf3 193 3 study study NN cord-292559-b21j9sf3 193 4 examined examine VBD cord-292559-b21j9sf3 193 5 the the DT cord-292559-b21j9sf3 193 6 structure structure NN cord-292559-b21j9sf3 193 7 of of IN cord-292559-b21j9sf3 193 8 cognition cognition NN cord-292559-b21j9sf3 193 9 and and CC cord-292559-b21j9sf3 193 10 found find VBD cord-292559-b21j9sf3 193 11 evidence evidence NN cord-292559-b21j9sf3 193 12 for for IN cord-292559-b21j9sf3 193 13 three three CD cord-292559-b21j9sf3 193 14 broad broad JJ cord-292559-b21j9sf3 193 15 factors factor NNS cord-292559-b21j9sf3 193 16 representing represent VBG cord-292559-b21j9sf3 193 17 general general JJ cord-292559-b21j9sf3 193 18 cognition cognition NN cord-292559-b21j9sf3 193 19 , , , cord-292559-b21j9sf3 193 20 executive executive JJ cord-292559-b21j9sf3 193 21 function function NN cord-292559-b21j9sf3 193 22 and and CC cord-292559-b21j9sf3 193 23 learning learning NN cord-292559-b21j9sf3 193 24 / / SYM cord-292559-b21j9sf3 193 25 memory memory NN cord-292559-b21j9sf3 193 26 [ [ -LRB- cord-292559-b21j9sf3 193 27 53 53 CD cord-292559-b21j9sf3 193 28 ] ] -RRB- cord-292559-b21j9sf3 193 29 , , , cord-292559-b21j9sf3 193 30 additionally additionally RB cord-292559-b21j9sf3 193 31 finding find VBG cord-292559-b21j9sf3 193 32 that that IN cord-292559-b21j9sf3 193 33 while while IN cord-292559-b21j9sf3 193 34 parent parent NN cord-292559-b21j9sf3 193 35 - - HYPH cord-292559-b21j9sf3 193 36 reported report VBN cord-292559-b21j9sf3 193 37 psychopathology psychopathology NN cord-292559-b21j9sf3 193 38 ( ( -LRB- cord-292559-b21j9sf3 193 39 perhaps perhaps RB cord-292559-b21j9sf3 193 40 especially especially RB cord-292559-b21j9sf3 193 41 externalizing externalize VBG cord-292559-b21j9sf3 193 42 symptoms symptom NNS cord-292559-b21j9sf3 193 43 and and CC cord-292559-b21j9sf3 193 44 stress stress NN cord-292559-b21j9sf3 193 45 reactivity reactivity NN cord-292559-b21j9sf3 193 46 ) ) -RRB- cord-292559-b21j9sf3 193 47 was be VBD cord-292559-b21j9sf3 193 48 associated associate VBN cord-292559-b21j9sf3 193 49 with with IN cord-292559-b21j9sf3 193 50 cognition cognition NN cord-292559-b21j9sf3 193 51 , , , cord-292559-b21j9sf3 193 52 the the DT cord-292559-b21j9sf3 193 53 sizes size NNS cord-292559-b21j9sf3 193 54 of of IN cord-292559-b21j9sf3 193 55 the the DT cord-292559-b21j9sf3 193 56 effects effect NNS cord-292559-b21j9sf3 193 57 were be VBD cord-292559-b21j9sf3 193 58 small small JJ cord-292559-b21j9sf3 193 59 in in IN cord-292559-b21j9sf3 193 60 magnitude magnitude NN cord-292559-b21j9sf3 193 61 . . . cord-292559-b21j9sf3 194 1 Furthermore furthermore RB cord-292559-b21j9sf3 194 2 , , , cord-292559-b21j9sf3 194 3 other other JJ cord-292559-b21j9sf3 194 4 emerging emerge VBG cord-292559-b21j9sf3 194 5 work work NN cord-292559-b21j9sf3 194 6 found find VBD cord-292559-b21j9sf3 194 7 little little JJ cord-292559-b21j9sf3 194 8 evidence evidence NN cord-292559-b21j9sf3 194 9 that that IN cord-292559-b21j9sf3 194 10 learning learn VBG cord-292559-b21j9sf3 194 11 a a DT cord-292559-b21j9sf3 194 12 second second JJ cord-292559-b21j9sf3 194 13 language language NN cord-292559-b21j9sf3 194 14 was be VBD cord-292559-b21j9sf3 194 15 associated associate VBN cord-292559-b21j9sf3 194 16 with with IN cord-292559-b21j9sf3 194 17 higher high JJR cord-292559-b21j9sf3 194 18 executive executive JJ cord-292559-b21j9sf3 194 19 functioning function VBG cord-292559-b21j9sf3 194 20 [ [ -LRB- cord-292559-b21j9sf3 194 21 54 54 CD cord-292559-b21j9sf3 194 22 ] ] -RRB- cord-292559-b21j9sf3 194 23 . . . cord-292559-b21j9sf3 195 1 Another another DT cord-292559-b21j9sf3 195 2 emerging emerge VBG cord-292559-b21j9sf3 195 3 study study NN cord-292559-b21j9sf3 195 4 examined examine VBD cord-292559-b21j9sf3 195 5 associations association NNS cord-292559-b21j9sf3 195 6 between between IN cord-292559-b21j9sf3 195 7 global global JJ cord-292559-b21j9sf3 195 8 cognition cognition NN cord-292559-b21j9sf3 195 9 and and CC cord-292559-b21j9sf3 195 10 healthrelated healthrelated JJ cord-292559-b21j9sf3 195 11 variables variable NNS cord-292559-b21j9sf3 195 12 , , , cord-292559-b21j9sf3 195 13 finding find VBG cord-292559-b21j9sf3 195 14 higher high JJR cord-292559-b21j9sf3 195 15 global global JJ cord-292559-b21j9sf3 195 16 cognition cognition NN cord-292559-b21j9sf3 195 17 scores score NNS cord-292559-b21j9sf3 195 18 were be VBD cord-292559-b21j9sf3 195 19 associated associate VBN cord-292559-b21j9sf3 195 20 with with IN cord-292559-b21j9sf3 195 21 meeting meeting NN cord-292559-b21j9sf3 195 22 recommendations recommendation NNS cord-292559-b21j9sf3 195 23 for for IN cord-292559-b21j9sf3 195 24 sleep sleep NN cord-292559-b21j9sf3 195 25 , , , cord-292559-b21j9sf3 195 26 screen screen NN cord-292559-b21j9sf3 195 27 time time NN cord-292559-b21j9sf3 195 28 , , , cord-292559-b21j9sf3 195 29 and and CC cord-292559-b21j9sf3 195 30 physical physical JJ cord-292559-b21j9sf3 195 31 activity activity NN cord-292559-b21j9sf3 195 32 [ [ -LRB- cord-292559-b21j9sf3 195 33 55 55 CD cord-292559-b21j9sf3 195 34 ] ] -RRB- cord-292559-b21j9sf3 195 35 . . . cord-292559-b21j9sf3 196 1 These these DT cord-292559-b21j9sf3 196 2 emerging emerge VBG cord-292559-b21j9sf3 196 3 studies study NNS cord-292559-b21j9sf3 196 4 provide provide VBP cord-292559-b21j9sf3 196 5 important important JJ cord-292559-b21j9sf3 196 6 information information NN cord-292559-b21j9sf3 196 7 that that WDT cord-292559-b21j9sf3 196 8 will will MD cord-292559-b21j9sf3 196 9 be be VB cord-292559-b21j9sf3 196 10 critical critical JJ cord-292559-b21j9sf3 196 11 for for IN cord-292559-b21j9sf3 196 12 understanding understand VBG cord-292559-b21j9sf3 196 13 the the DT cord-292559-b21j9sf3 196 14 development development NN cord-292559-b21j9sf3 196 15 of of IN cord-292559-b21j9sf3 196 16 risk risk NN cord-292559-b21j9sf3 196 17 for for IN cord-292559-b21j9sf3 196 18 physical physical JJ cord-292559-b21j9sf3 196 19 and and CC cord-292559-b21j9sf3 196 20 mental mental JJ cord-292559-b21j9sf3 196 21 health health NN cord-292559-b21j9sf3 196 22 - - HYPH cord-292559-b21j9sf3 196 23 related relate VBN cord-292559-b21j9sf3 196 24 outcomes outcome NNS cord-292559-b21j9sf3 196 25 , , , cord-292559-b21j9sf3 196 26 as as RB cord-292559-b21j9sf3 196 27 well well RB cord-292559-b21j9sf3 196 28 as as IN cord-292559-b21j9sf3 196 29 several several JJ cord-292559-b21j9sf3 196 30 potential potential JJ cord-292559-b21j9sf3 196 31 avenues avenue NNS cord-292559-b21j9sf3 196 32 for for IN cord-292559-b21j9sf3 196 33 the the DT cord-292559-b21j9sf3 196 34 development development NN cord-292559-b21j9sf3 196 35 of of IN cord-292559-b21j9sf3 196 36 health health NN cord-292559-b21j9sf3 196 37 - - HYPH cord-292559-b21j9sf3 196 38 related relate VBN cord-292559-b21j9sf3 196 39 resources resource NNS cord-292559-b21j9sf3 196 40 and and CC cord-292559-b21j9sf3 196 41 interventions intervention NNS cord-292559-b21j9sf3 196 42 . . . cord-292559-b21j9sf3 197 1 Youth youth NN cord-292559-b21j9sf3 197 2 behavior behavior NN cord-292559-b21j9sf3 197 3 and and CC cord-292559-b21j9sf3 197 4 brain brain NN cord-292559-b21j9sf3 197 5 structure structure NN cord-292559-b21j9sf3 197 6 , , , cord-292559-b21j9sf3 197 7 function function NN cord-292559-b21j9sf3 197 8 , , , cord-292559-b21j9sf3 197 9 and and CC cord-292559-b21j9sf3 197 10 connectivity connectivity NN cord-292559-b21j9sf3 197 11 . . . cord-292559-b21j9sf3 198 1 Research research NN cord-292559-b21j9sf3 198 2 has have VBZ cord-292559-b21j9sf3 198 3 begun begin VBN cord-292559-b21j9sf3 198 4 to to TO cord-292559-b21j9sf3 198 5 utilize utilize VB cord-292559-b21j9sf3 198 6 the the DT cord-292559-b21j9sf3 198 7 wealth wealth NN cord-292559-b21j9sf3 198 8 of of IN cord-292559-b21j9sf3 198 9 neuroimaging neuroimage VBG cord-292559-b21j9sf3 198 10 data datum NNS cord-292559-b21j9sf3 198 11 available available JJ cord-292559-b21j9sf3 198 12 from from IN cord-292559-b21j9sf3 198 13 the the DT cord-292559-b21j9sf3 198 14 baseline baseline JJ cord-292559-b21j9sf3 198 15 sample sample NN cord-292559-b21j9sf3 198 16 ( ( -LRB- cord-292559-b21j9sf3 198 17 i.e. i.e. FW cord-292559-b21j9sf3 198 18 , , , cord-292559-b21j9sf3 198 19 Data data NN cord-292559-b21j9sf3 198 20 Releases release VBZ cord-292559-b21j9sf3 198 21 1.1 1.1 CD cord-292559-b21j9sf3 198 22 and and CC cord-292559-b21j9sf3 198 23 2.0.1 2.0.1 CD cord-292559-b21j9sf3 198 24 ) ) -RRB- cord-292559-b21j9sf3 198 25 in in IN cord-292559-b21j9sf3 198 26 novel novel JJ cord-292559-b21j9sf3 198 27 and and CC cord-292559-b21j9sf3 198 28 innovative innovative JJ cord-292559-b21j9sf3 198 29 ways way NNS cord-292559-b21j9sf3 198 30 to to TO cord-292559-b21j9sf3 198 31 begin begin VB cord-292559-b21j9sf3 198 32 to to TO cord-292559-b21j9sf3 198 33 analyze analyze VB cord-292559-b21j9sf3 198 34 important important JJ cord-292559-b21j9sf3 198 35 questions question NNS cord-292559-b21j9sf3 198 36 about about IN cord-292559-b21j9sf3 198 37 early early JJ cord-292559-b21j9sf3 198 38 neural neural JJ cord-292559-b21j9sf3 198 39 markers marker NNS cord-292559-b21j9sf3 198 40 of of IN cord-292559-b21j9sf3 198 41 risk risk NN cord-292559-b21j9sf3 198 42 . . . cord-292559-b21j9sf3 199 1 Emerging emerge VBG cord-292559-b21j9sf3 199 2 research research NN cord-292559-b21j9sf3 199 3 examining examine VBG cord-292559-b21j9sf3 199 4 resting rest VBG cord-292559-b21j9sf3 199 5 state state NN cord-292559-b21j9sf3 199 6 functional functional JJ cord-292559-b21j9sf3 199 7 connectivity connectivity NN cord-292559-b21j9sf3 199 8 ( ( -LRB- cord-292559-b21j9sf3 199 9 RSFC RSFC NNP cord-292559-b21j9sf3 199 10 ) ) -RRB- cord-292559-b21j9sf3 199 11 to to TO cord-292559-b21j9sf3 199 12 delineate delineate VB cord-292559-b21j9sf3 199 13 the the DT cord-292559-b21j9sf3 199 14 functional functional JJ cord-292559-b21j9sf3 199 15 architecture architecture NN cord-292559-b21j9sf3 199 16 of of IN cord-292559-b21j9sf3 199 17 the the DT cord-292559-b21j9sf3 199 18 brain brain NN cord-292559-b21j9sf3 199 19 found find VBD cord-292559-b21j9sf3 199 20 RSFC RSFC NNP cord-292559-b21j9sf3 199 21 networks network NNS cord-292559-b21j9sf3 199 22 were be VBD cord-292559-b21j9sf3 199 23 highly highly RB cord-292559-b21j9sf3 199 24 reproducible reproducible JJ cord-292559-b21j9sf3 199 25 across across IN cord-292559-b21j9sf3 199 26 two two CD cord-292559-b21j9sf3 199 27 samples sample NNS cord-292559-b21j9sf3 199 28 of of IN cord-292559-b21j9sf3 199 29 ABCD ABCD NNP cord-292559-b21j9sf3 199 30 Study Study NNP cord-292559-b21j9sf3 199 31 data datum NNS cord-292559-b21j9sf3 199 32 , , , cord-292559-b21j9sf3 199 33 shared share VBD cord-292559-b21j9sf3 199 34 many many JJ cord-292559-b21j9sf3 199 35 features feature NNS cord-292559-b21j9sf3 199 36 of of IN cord-292559-b21j9sf3 199 37 adult adult NN cord-292559-b21j9sf3 199 38 - - HYPH cord-292559-b21j9sf3 199 39 level level NN cord-292559-b21j9sf3 199 40 networks network NNS cord-292559-b21j9sf3 199 41 , , , cord-292559-b21j9sf3 199 42 and and CC cord-292559-b21j9sf3 199 43 showed show VBD cord-292559-b21j9sf3 199 44 associations association NNS cord-292559-b21j9sf3 199 45 with with IN cord-292559-b21j9sf3 199 46 cognitive cognitive JJ cord-292559-b21j9sf3 199 47 functioning function VBG cord-292559-b21j9sf3 199 48 [ [ -LRB- cord-292559-b21j9sf3 199 49 42 42 CD cord-292559-b21j9sf3 199 50 ] ] -RRB- cord-292559-b21j9sf3 199 51 . . . cord-292559-b21j9sf3 200 1 Other other JJ cord-292559-b21j9sf3 200 2 emerging emerge VBG cord-292559-b21j9sf3 200 3 research research NN cord-292559-b21j9sf3 200 4 found find VBD cord-292559-b21j9sf3 200 5 RSFC RSFC NNP cord-292559-b21j9sf3 200 6 associations association NNS cord-292559-b21j9sf3 200 7 with with IN cord-292559-b21j9sf3 200 8 general general JJ cord-292559-b21j9sf3 200 9 cognitive cognitive JJ cord-292559-b21j9sf3 200 10 ability ability NN cord-292559-b21j9sf3 200 11 were be VBD cord-292559-b21j9sf3 200 12 generalizable generalizable JJ cord-292559-b21j9sf3 200 13 across across IN cord-292559-b21j9sf3 200 14 ABCD ABCD NNP cord-292559-b21j9sf3 200 15 Study Study NNP cord-292559-b21j9sf3 200 16 sites site NNS cord-292559-b21j9sf3 200 17 and and CC cord-292559-b21j9sf3 200 18 that that IN cord-292559-b21j9sf3 200 19 RSFC RSFC NNP cord-292559-b21j9sf3 200 20 within within IN cord-292559-b21j9sf3 200 21 and and CC cord-292559-b21j9sf3 200 22 between between IN cord-292559-b21j9sf3 200 23 task task NN cord-292559-b21j9sf3 200 24 control control NN cord-292559-b21j9sf3 200 25 networks network NNS cord-292559-b21j9sf3 200 26 were be VBD cord-292559-b21j9sf3 200 27 associated associate VBN cord-292559-b21j9sf3 200 28 with with IN cord-292559-b21j9sf3 200 29 variability variability NN cord-292559-b21j9sf3 200 30 in in IN cord-292559-b21j9sf3 200 31 general general JJ cord-292559-b21j9sf3 200 32 cognitive cognitive JJ cord-292559-b21j9sf3 200 33 ability ability NN cord-292559-b21j9sf3 200 34 [ [ -LRB- cord-292559-b21j9sf3 200 35 56 56 CD cord-292559-b21j9sf3 200 36 ] ] -RRB- cord-292559-b21j9sf3 200 37 . . . cord-292559-b21j9sf3 201 1 Other other JJ cord-292559-b21j9sf3 201 2 emerging emerge VBG cord-292559-b21j9sf3 201 3 work work NN cord-292559-b21j9sf3 201 4 examining examine VBG cord-292559-b21j9sf3 201 5 brain brain NN cord-292559-b21j9sf3 201 6 - - HYPH cord-292559-b21j9sf3 201 7 cognition cognition NN cord-292559-b21j9sf3 201 8 associations association NNS cord-292559-b21j9sf3 201 9 found find VBD cord-292559-b21j9sf3 201 10 that that IN cord-292559-b21j9sf3 201 11 with with IN cord-292559-b21j9sf3 201 12 higher high JJR cord-292559-b21j9sf3 201 13 risk risk NN cord-292559-b21j9sf3 201 14 of of IN cord-292559-b21j9sf3 201 15 lead lead JJ cord-292559-b21j9sf3 201 16 exposure exposure NN cord-292559-b21j9sf3 201 17 , , , cord-292559-b21j9sf3 201 18 lower low JJR cord-292559-b21j9sf3 201 19 family family NN cord-292559-b21j9sf3 201 20 income income NN cord-292559-b21j9sf3 201 21 was be VBD cord-292559-b21j9sf3 201 22 associated associate VBN cord-292559-b21j9sf3 201 23 with with IN cord-292559-b21j9sf3 201 24 lower low JJR cord-292559-b21j9sf3 201 25 cognitive cognitive JJ cord-292559-b21j9sf3 201 26 functioning functioning NN cord-292559-b21j9sf3 201 27 , , , cord-292559-b21j9sf3 201 28 lower low JJR cord-292559-b21j9sf3 201 29 cortical cortical JJ cord-292559-b21j9sf3 201 30 volume volume NN cord-292559-b21j9sf3 201 31 , , , cord-292559-b21j9sf3 201 32 and and CC cord-292559-b21j9sf3 201 33 lower low JJR cord-292559-b21j9sf3 201 34 surface surface NN cord-292559-b21j9sf3 201 35 area area NN cord-292559-b21j9sf3 201 36 [ [ -LRB- cord-292559-b21j9sf3 201 37 57 57 CD cord-292559-b21j9sf3 201 38 ] ] -RRB- cord-292559-b21j9sf3 201 39 . . . cord-292559-b21j9sf3 202 1 Emerging emerge VBG cord-292559-b21j9sf3 202 2 findings finding NNS cord-292559-b21j9sf3 202 3 also also RB cord-292559-b21j9sf3 202 4 found find VBD cord-292559-b21j9sf3 202 5 higher high JJR cord-292559-b21j9sf3 202 6 screen screen NN cord-292559-b21j9sf3 202 7 media medium NNS cord-292559-b21j9sf3 202 8 activity activity NN cord-292559-b21j9sf3 202 9 was be VBD cord-292559-b21j9sf3 202 10 associated associate VBN cord-292559-b21j9sf3 202 11 visual visual JJ cord-292559-b21j9sf3 202 12 brain brain NN cord-292559-b21j9sf3 202 13 areas area NNS cord-292559-b21j9sf3 202 14 ( ( -LRB- cord-292559-b21j9sf3 202 15 e.g. e.g. RB cord-292559-b21j9sf3 202 16 , , , cord-292559-b21j9sf3 202 17 occipital occipital JJ cord-292559-b21j9sf3 202 18 cortex cortex NNP cord-292559-b21j9sf3 202 19 ) ) -RRB- cord-292559-b21j9sf3 202 20 [ [ -LRB- cord-292559-b21j9sf3 202 21 58 58 CD cord-292559-b21j9sf3 202 22 ] ] -RRB- cord-292559-b21j9sf3 202 23 , , , cord-292559-b21j9sf3 202 24 with with IN cord-292559-b21j9sf3 202 25 these these DT cord-292559-b21j9sf3 202 26 associations association NNS cord-292559-b21j9sf3 202 27 showing show VBG cord-292559-b21j9sf3 202 28 mixed mixed JJ cord-292559-b21j9sf3 202 29 positive positive JJ cord-292559-b21j9sf3 202 30 and and CC cord-292559-b21j9sf3 202 31 negative negative JJ cord-292559-b21j9sf3 202 32 relations relation NNS cord-292559-b21j9sf3 202 33 to to IN cord-292559-b21j9sf3 202 34 cognitive cognitive JJ cord-292559-b21j9sf3 202 35 functioning functioning NN cord-292559-b21j9sf3 202 36 . . . cord-292559-b21j9sf3 203 1 Other other JJ cord-292559-b21j9sf3 203 2 emerging emerge VBG cord-292559-b21j9sf3 203 3 baseline baseline JJ cord-292559-b21j9sf3 203 4 research research NN cord-292559-b21j9sf3 203 5 has have VBZ cord-292559-b21j9sf3 203 6 found find VBN cord-292559-b21j9sf3 203 7 that that IN cord-292559-b21j9sf3 203 8 higher high JJR cord-292559-b21j9sf3 203 9 BMI BMI NNP cord-292559-b21j9sf3 203 10 is be VBZ cord-292559-b21j9sf3 203 11 associated associate VBN cord-292559-b21j9sf3 203 12 with with IN cord-292559-b21j9sf3 203 13 lower low JJR cord-292559-b21j9sf3 203 14 cortical cortical JJ cord-292559-b21j9sf3 203 15 thickness thickness NN cord-292559-b21j9sf3 203 16 , , , cord-292559-b21j9sf3 203 17 especially especially RB cord-292559-b21j9sf3 203 18 in in IN cord-292559-b21j9sf3 203 19 prefrontal prefrontal JJ cord-292559-b21j9sf3 203 20 regions region NNS cord-292559-b21j9sf3 203 21 , , , cord-292559-b21j9sf3 203 22 and and CC cord-292559-b21j9sf3 203 23 lower low JJR cord-292559-b21j9sf3 203 24 executive executive JJ cord-292559-b21j9sf3 203 25 functioning function VBG cord-292559-b21j9sf3 203 26 performance performance NN cord-292559-b21j9sf3 203 27 [ [ -LRB- cord-292559-b21j9sf3 203 28 59 59 CD cord-292559-b21j9sf3 203 29 , , , cord-292559-b21j9sf3 203 30 60 60 CD cord-292559-b21j9sf3 203 31 ] ] -RRB- cord-292559-b21j9sf3 203 32 . . . cord-292559-b21j9sf3 204 1 Interestingly interestingly RB cord-292559-b21j9sf3 204 2 , , , cord-292559-b21j9sf3 204 3 other other JJ cord-292559-b21j9sf3 204 4 emerging emerge VBG cord-292559-b21j9sf3 204 5 work work NN cord-292559-b21j9sf3 204 6 found find VBD cord-292559-b21j9sf3 204 7 an an DT cord-292559-b21j9sf3 204 8 association association NN cord-292559-b21j9sf3 204 9 between between IN cord-292559-b21j9sf3 204 10 sleep sleep NN cord-292559-b21j9sf3 204 11 duration duration NN cord-292559-b21j9sf3 204 12 and and CC cord-292559-b21j9sf3 204 13 both both DT cord-292559-b21j9sf3 204 14 cognitive cognitive JJ cord-292559-b21j9sf3 204 15 function function NN cord-292559-b21j9sf3 204 16 and and CC cord-292559-b21j9sf3 204 17 psychopathology psychopathology NN cord-292559-b21j9sf3 204 18 in in IN cord-292559-b21j9sf3 204 19 youth youth NN cord-292559-b21j9sf3 204 20 , , , cord-292559-b21j9sf3 204 21 as as RB cord-292559-b21j9sf3 204 22 well well RB cord-292559-b21j9sf3 204 23 as as IN cord-292559-b21j9sf3 204 24 with with IN cord-292559-b21j9sf3 204 25 variation variation NN cord-292559-b21j9sf3 204 26 in in IN cord-292559-b21j9sf3 204 27 brain brain NN cord-292559-b21j9sf3 204 28 volume volume NN cord-292559-b21j9sf3 204 29 in in IN cord-292559-b21j9sf3 204 30 a a DT cord-292559-b21j9sf3 204 31 variety variety NN cord-292559-b21j9sf3 204 32 of of IN cord-292559-b21j9sf3 204 33 regions region NNS cord-292559-b21j9sf3 204 34 in in IN cord-292559-b21j9sf3 204 35 the the DT cord-292559-b21j9sf3 204 36 prefrontal prefrontal JJ cord-292559-b21j9sf3 204 37 , , , cord-292559-b21j9sf3 204 38 parietal parietal JJ cord-292559-b21j9sf3 204 39 , , , cord-292559-b21j9sf3 204 40 and and CC cord-292559-b21j9sf3 204 41 temporal temporal JJ cord-292559-b21j9sf3 204 42 cortices cortex NNS cord-292559-b21j9sf3 204 43 [ [ -LRB- cord-292559-b21j9sf3 204 44 39 39 CD cord-292559-b21j9sf3 204 45 ] ] -RRB- cord-292559-b21j9sf3 204 46 . . . cord-292559-b21j9sf3 205 1 Furthermore furthermore RB cord-292559-b21j9sf3 205 2 , , , cord-292559-b21j9sf3 205 3 hippocampal hippocampal JJ cord-292559-b21j9sf3 205 4 volume volume NN cord-292559-b21j9sf3 205 5 was be VBD cord-292559-b21j9sf3 205 6 associated associate VBN cord-292559-b21j9sf3 205 7 with with IN cord-292559-b21j9sf3 205 8 depressive depressive JJ cord-292559-b21j9sf3 205 9 symptoms symptom NNS cord-292559-b21j9sf3 205 10 in in IN cord-292559-b21j9sf3 205 11 males male NNS cord-292559-b21j9sf3 205 12 and and CC cord-292559-b21j9sf3 205 13 involvement involvement NN cord-292559-b21j9sf3 205 14 in in IN cord-292559-b21j9sf3 205 15 sports sport NNS cord-292559-b21j9sf3 205 16 was be VBD cord-292559-b21j9sf3 205 17 associated associate VBN cord-292559-b21j9sf3 205 18 with with IN cord-292559-b21j9sf3 205 19 fewer few JJR cord-292559-b21j9sf3 205 20 depressive depressive JJ cord-292559-b21j9sf3 205 21 symptoms symptom NNS cord-292559-b21j9sf3 205 22 , , , cord-292559-b21j9sf3 205 23 with with IN cord-292559-b21j9sf3 205 24 some some DT cord-292559-b21j9sf3 205 25 evidence evidence NN cord-292559-b21j9sf3 205 26 that that IN cord-292559-b21j9sf3 205 27 hippocampal hippocampal JJ cord-292559-b21j9sf3 205 28 volume volume NN cord-292559-b21j9sf3 205 29 mediated mediate VBD cord-292559-b21j9sf3 205 30 the the DT cord-292559-b21j9sf3 205 31 association association NN cord-292559-b21j9sf3 205 32 between between IN cord-292559-b21j9sf3 205 33 sports sport NNS cord-292559-b21j9sf3 205 34 involvement involvement NN cord-292559-b21j9sf3 205 35 and and CC cord-292559-b21j9sf3 205 36 depressive depressive JJ cord-292559-b21j9sf3 205 37 symptoms symptom NNS cord-292559-b21j9sf3 205 38 [ [ -LRB- cord-292559-b21j9sf3 205 39 61 61 CD cord-292559-b21j9sf3 205 40 ] ] -RRB- cord-292559-b21j9sf3 205 41 . . . cord-292559-b21j9sf3 206 1 Other other JJ cord-292559-b21j9sf3 206 2 emerging emerge VBG cord-292559-b21j9sf3 206 3 research research NN cord-292559-b21j9sf3 206 4 found find VBD cord-292559-b21j9sf3 206 5 risk risk NN cord-292559-b21j9sf3 206 6 for for IN cord-292559-b21j9sf3 206 7 depression depression NN cord-292559-b21j9sf3 206 8 , , , cord-292559-b21j9sf3 206 9 as as IN cord-292559-b21j9sf3 206 10 assessed assess VBN cord-292559-b21j9sf3 206 11 by by IN cord-292559-b21j9sf3 206 12 parental parental JJ cord-292559-b21j9sf3 206 13 history history NN cord-292559-b21j9sf3 206 14 of of IN cord-292559-b21j9sf3 206 15 depression depression NN cord-292559-b21j9sf3 206 16 , , , cord-292559-b21j9sf3 206 17 was be VBD cord-292559-b21j9sf3 206 18 associated associate VBN cord-292559-b21j9sf3 206 19 with with IN cord-292559-b21j9sf3 206 20 lower low JJR cord-292559-b21j9sf3 206 21 putamen putamen NN cord-292559-b21j9sf3 206 22 volume volume NN cord-292559-b21j9sf3 206 23 [ [ -LRB- cord-292559-b21j9sf3 206 24 43 43 CD cord-292559-b21j9sf3 206 25 ] ] -RRB- cord-292559-b21j9sf3 206 26 . . . cord-292559-b21j9sf3 207 1 Further further RB cord-292559-b21j9sf3 207 2 , , , cord-292559-b21j9sf3 207 3 emerging emerge VBG cord-292559-b21j9sf3 207 4 research research NN cord-292559-b21j9sf3 207 5 examining examine VBG cord-292559-b21j9sf3 207 6 specifically specifically RB cord-292559-b21j9sf3 207 7 anhedonia anhedonia NNP cord-292559-b21j9sf3 207 8 found find VBD cord-292559-b21j9sf3 207 9 associations association NNS cord-292559-b21j9sf3 207 10 with with IN cord-292559-b21j9sf3 207 11 hypoconnectivity hypoconnectivity NN cord-292559-b21j9sf3 207 12 in in IN cord-292559-b21j9sf3 207 13 several several JJ cord-292559-b21j9sf3 207 14 RSFC RSFC NNP cord-292559-b21j9sf3 207 15 networks network NNS cord-292559-b21j9sf3 207 16 , , , cord-292559-b21j9sf3 207 17 as as RB cord-292559-b21j9sf3 207 18 well well RB cord-292559-b21j9sf3 207 19 as as IN cord-292559-b21j9sf3 207 20 lower low JJR cord-292559-b21j9sf3 207 21 activation activation NN cord-292559-b21j9sf3 207 22 compared compare VBN cord-292559-b21j9sf3 207 23 to to IN cord-292559-b21j9sf3 207 24 a a DT cord-292559-b21j9sf3 207 25 group group NN cord-292559-b21j9sf3 207 26 not not RB cord-292559-b21j9sf3 207 27 endorsing endorse VBG cord-292559-b21j9sf3 207 28 anhedonia anhedonia NNP cord-292559-b21j9sf3 207 29 during during IN cord-292559-b21j9sf3 207 30 reward reward NN cord-292559-b21j9sf3 207 31 anticipation anticipation NN cord-292559-b21j9sf3 207 32 , , , cord-292559-b21j9sf3 207 33 including include VBG cord-292559-b21j9sf3 207 34 in in IN cord-292559-b21j9sf3 207 35 cingulo cingulo NNP cord-292559-b21j9sf3 207 36 - - HYPH cord-292559-b21j9sf3 207 37 opercular opercular JJ cord-292559-b21j9sf3 207 38 ( ( -LRB- cord-292559-b21j9sf3 207 39 CON con NN cord-292559-b21j9sf3 207 40 ) ) -RRB- cord-292559-b21j9sf3 207 41 network network NN cord-292559-b21j9sf3 207 42 regions region NNS cord-292559-b21j9sf3 207 43 and and CC cord-292559-b21j9sf3 207 44 the the DT cord-292559-b21j9sf3 207 45 striatum striatum NN cord-292559-b21j9sf3 207 46 [ [ -LRB- cord-292559-b21j9sf3 207 47 62 62 CD cord-292559-b21j9sf3 207 48 ] ] -RRB- cord-292559-b21j9sf3 207 49 . . . cord-292559-b21j9sf3 208 1 Other other JJ cord-292559-b21j9sf3 208 2 emerging emerge VBG cord-292559-b21j9sf3 208 3 research research NN cord-292559-b21j9sf3 208 4 found find VBD cord-292559-b21j9sf3 208 5 evidence evidence NN cord-292559-b21j9sf3 208 6 that that IN cord-292559-b21j9sf3 208 7 higher high JJR cord-292559-b21j9sf3 208 8 PLEs ple NNS cord-292559-b21j9sf3 208 9 were be VBD cord-292559-b21j9sf3 208 10 associated associate VBN cord-292559-b21j9sf3 208 11 with with IN cord-292559-b21j9sf3 208 12 lower low JJR cord-292559-b21j9sf3 208 13 functional functional JJ cord-292559-b21j9sf3 208 14 connectivity connectivity NN cord-292559-b21j9sf3 208 15 in in IN cord-292559-b21j9sf3 208 16 several several JJ cord-292559-b21j9sf3 208 17 RSFC RSFC NNP cord-292559-b21j9sf3 208 18 networks network NNS cord-292559-b21j9sf3 208 19 , , , cord-292559-b21j9sf3 208 20 including include VBG cord-292559-b21j9sf3 208 21 lower low JJR cord-292559-b21j9sf3 208 22 CON con NN cord-292559-b21j9sf3 208 23 and and CC cord-292559-b21j9sf3 208 24 default default NN cord-292559-b21j9sf3 208 25 mode mode NN cord-292559-b21j9sf3 208 26 connectivity connectivity NN cord-292559-b21j9sf3 208 27 [ [ -LRB- cord-292559-b21j9sf3 208 28 63 63 CD cord-292559-b21j9sf3 208 29 ] ] -RRB- cord-292559-b21j9sf3 208 30 . . . cord-292559-b21j9sf3 209 1 Another another DT cord-292559-b21j9sf3 209 2 interesting interesting JJ cord-292559-b21j9sf3 209 3 emerging emerge VBG cord-292559-b21j9sf3 209 4 study study NN cord-292559-b21j9sf3 209 5 found find VBD cord-292559-b21j9sf3 209 6 youth youth NN cord-292559-b21j9sf3 209 7 with with IN cord-292559-b21j9sf3 209 8 disruptive disruptive JJ cord-292559-b21j9sf3 209 9 behavior behavior NN cord-292559-b21j9sf3 209 10 problems problem NNS cord-292559-b21j9sf3 209 11 who who WP cord-292559-b21j9sf3 209 12 also also RB cord-292559-b21j9sf3 209 13 had have VBD cord-292559-b21j9sf3 209 14 callous callous JJ cord-292559-b21j9sf3 209 15 and and CC cord-292559-b21j9sf3 209 16 unemotional unemotional JJ cord-292559-b21j9sf3 209 17 traits trait NNS cord-292559-b21j9sf3 209 18 showed show VBD cord-292559-b21j9sf3 209 19 lower low JJR cord-292559-b21j9sf3 209 20 gray gray JJ cord-292559-b21j9sf3 209 21 matter matter NN cord-292559-b21j9sf3 209 22 in in IN cord-292559-b21j9sf3 209 23 the the DT cord-292559-b21j9sf3 209 24 amygdala amygdala NN cord-292559-b21j9sf3 209 25 and and CC cord-292559-b21j9sf3 209 26 the the DT cord-292559-b21j9sf3 209 27 insula insula NN cord-292559-b21j9sf3 209 28 compared compare VBN cord-292559-b21j9sf3 209 29 to to IN cord-292559-b21j9sf3 209 30 typically typically RB cord-292559-b21j9sf3 209 31 - - HYPH cord-292559-b21j9sf3 209 32 developing develop VBG cord-292559-b21j9sf3 209 33 youth youth NN cord-292559-b21j9sf3 209 34 . . . cord-292559-b21j9sf3 210 1 Further further RB cord-292559-b21j9sf3 210 2 , , , cord-292559-b21j9sf3 210 3 youth youth NN cord-292559-b21j9sf3 210 4 with with IN cord-292559-b21j9sf3 210 5 disruptive disruptive JJ cord-292559-b21j9sf3 210 6 behavior behavior NN cord-292559-b21j9sf3 210 7 problems problem NNS cord-292559-b21j9sf3 210 8 with with IN cord-292559-b21j9sf3 210 9 and and CC cord-292559-b21j9sf3 210 10 without without IN cord-292559-b21j9sf3 210 11 callous/ callous/ CD cord-292559-b21j9sf3 210 12 unemotional unemotional JJ cord-292559-b21j9sf3 210 13 traits trait NNS cord-292559-b21j9sf3 210 14 showed show VBD cord-292559-b21j9sf3 210 15 alterations alteration NNS cord-292559-b21j9sf3 210 16 in in IN cord-292559-b21j9sf3 210 17 several several JJ cord-292559-b21j9sf3 210 18 regions region NNS cord-292559-b21j9sf3 210 19 including include VBG cord-292559-b21j9sf3 210 20 lower low JJR cord-292559-b21j9sf3 210 21 hippocampal hippocampal JJ cord-292559-b21j9sf3 210 22 volume volume NN cord-292559-b21j9sf3 210 23 , , , cord-292559-b21j9sf3 210 24 though though IN cord-292559-b21j9sf3 210 25 it -PRON- PRP cord-292559-b21j9sf3 210 26 was be VBD cord-292559-b21j9sf3 210 27 limited limit VBN cord-292559-b21j9sf3 210 28 to to IN cord-292559-b21j9sf3 210 29 the the DT cord-292559-b21j9sf3 210 30 left left JJ cord-292559-b21j9sf3 210 31 hippocampus hippocampus NN cord-292559-b21j9sf3 210 32 in in IN cord-292559-b21j9sf3 210 33 disruptive disruptive JJ cord-292559-b21j9sf3 210 34 youth youth NN cord-292559-b21j9sf3 210 35 without without IN cord-292559-b21j9sf3 210 36 callous callous JJ cord-292559-b21j9sf3 210 37 / / SYM cord-292559-b21j9sf3 210 38 unemotional unemotional JJ cord-292559-b21j9sf3 210 39 traits trait NNS cord-292559-b21j9sf3 210 40 [ [ -LRB- cord-292559-b21j9sf3 210 41 64 64 CD cord-292559-b21j9sf3 210 42 ] ] -RRB- cord-292559-b21j9sf3 210 43 . . . cord-292559-b21j9sf3 211 1 Collectively collectively RB cord-292559-b21j9sf3 211 2 such such JJ cord-292559-b21j9sf3 211 3 data datum NNS cord-292559-b21j9sf3 211 4 begin begin VBP cord-292559-b21j9sf3 211 5 to to TO cord-292559-b21j9sf3 211 6 establish establish VB cord-292559-b21j9sf3 211 7 the the DT cord-292559-b21j9sf3 211 8 early early JJ cord-292559-b21j9sf3 211 9 emergence emergence NN cord-292559-b21j9sf3 211 10 of of IN cord-292559-b21j9sf3 211 11 alterations alteration NNS cord-292559-b21j9sf3 211 12 in in IN cord-292559-b21j9sf3 211 13 brain brain NN cord-292559-b21j9sf3 211 14 structure structure NN cord-292559-b21j9sf3 211 15 , , , cord-292559-b21j9sf3 211 16 function function NN cord-292559-b21j9sf3 211 17 and and CC cord-292559-b21j9sf3 211 18 connectivity connectivity NN cord-292559-b21j9sf3 211 19 associated associate VBN cord-292559-b21j9sf3 211 20 with with IN cord-292559-b21j9sf3 211 21 a a DT cord-292559-b21j9sf3 211 22 range range NN cord-292559-b21j9sf3 211 23 of of IN cord-292559-b21j9sf3 211 24 forms form NNS cord-292559-b21j9sf3 211 25 of of IN cord-292559-b21j9sf3 211 26 psychopathology psychopathology NN cord-292559-b21j9sf3 211 27 and and CC cord-292559-b21j9sf3 211 28 individual individual JJ cord-292559-b21j9sf3 211 29 differences difference NNS cord-292559-b21j9sf3 211 30 in in IN cord-292559-b21j9sf3 211 31 cognitive cognitive JJ cord-292559-b21j9sf3 211 32 function function NN cord-292559-b21j9sf3 211 33 and and CC cord-292559-b21j9sf3 211 34 behavior behavior NN cord-292559-b21j9sf3 211 35 , , , cord-292559-b21j9sf3 211 36 as as RB cord-292559-b21j9sf3 211 37 well well RB cord-292559-b21j9sf3 211 38 as as IN cord-292559-b21j9sf3 211 39 critical critical JJ cord-292559-b21j9sf3 211 40 environmental environmental JJ cord-292559-b21j9sf3 211 41 influences influence NNS cord-292559-b21j9sf3 211 42 that that WDT cord-292559-b21j9sf3 211 43 shape shape VBP cord-292559-b21j9sf3 211 44 brain brain NN cord-292559-b21j9sf3 211 45 development development NN cord-292559-b21j9sf3 211 46 . . . cord-292559-b21j9sf3 212 1 Crucially crucially RB cord-292559-b21j9sf3 212 2 , , , cord-292559-b21j9sf3 212 3 they -PRON- PRP cord-292559-b21j9sf3 212 4 also also RB cord-292559-b21j9sf3 212 5 begin begin VBP cord-292559-b21j9sf3 212 6 to to TO cord-292559-b21j9sf3 212 7 identify identify VB cord-292559-b21j9sf3 212 8 both both DT cord-292559-b21j9sf3 212 9 commonalities commonality NNS cord-292559-b21j9sf3 212 10 and and CC cord-292559-b21j9sf3 212 11 dissociations dissociation NNS cord-292559-b21j9sf3 212 12 in in IN cord-292559-b21j9sf3 212 13 these these DT cord-292559-b21j9sf3 212 14 relationships relationship NNS cord-292559-b21j9sf3 212 15 . . . cord-292559-b21j9sf3 213 1 For for IN cord-292559-b21j9sf3 213 2 example example NN cord-292559-b21j9sf3 213 3 , , , cord-292559-b21j9sf3 213 4 lower low JJR cord-292559-b21j9sf3 213 5 hippocampal hippocampal JJ cord-292559-b21j9sf3 213 6 volume volume NN cord-292559-b21j9sf3 213 7 has have VBZ cord-292559-b21j9sf3 213 8 been be VBN cord-292559-b21j9sf3 213 9 associated associate VBN cord-292559-b21j9sf3 213 10 with with IN cord-292559-b21j9sf3 213 11 both both DT cord-292559-b21j9sf3 213 12 depression depression NN cord-292559-b21j9sf3 213 13 and and CC cord-292559-b21j9sf3 213 14 disruptive disruptive JJ cord-292559-b21j9sf3 213 15 behavior behavior NN cord-292559-b21j9sf3 213 16 , , , cord-292559-b21j9sf3 213 17 while while IN cord-292559-b21j9sf3 213 18 lower low JJR cord-292559-b21j9sf3 213 19 amygdala amygdala NNP cord-292559-b21j9sf3 213 20 volume volume NN cord-292559-b21j9sf3 213 21 has have VBZ cord-292559-b21j9sf3 213 22 only only RB cord-292559-b21j9sf3 213 23 been be VBN cord-292559-b21j9sf3 213 24 associated associate VBN cord-292559-b21j9sf3 213 25 with with IN cord-292559-b21j9sf3 213 26 disruptive disruptive JJ cord-292559-b21j9sf3 213 27 behavior behavior NN cord-292559-b21j9sf3 213 28 . . . cord-292559-b21j9sf3 214 1 In in IN cord-292559-b21j9sf3 214 2 terms term NNS cord-292559-b21j9sf3 214 3 of of IN cord-292559-b21j9sf3 214 4 connectivity connectivity NN cord-292559-b21j9sf3 214 5 , , , cord-292559-b21j9sf3 214 6 disruption disruption NN cord-292559-b21j9sf3 214 7 in in IN cord-292559-b21j9sf3 214 8 the the DT cord-292559-b21j9sf3 214 9 connectivity connectivity NN cord-292559-b21j9sf3 214 10 of of IN cord-292559-b21j9sf3 214 11 the the DT cord-292559-b21j9sf3 214 12 CON con NN cord-292559-b21j9sf3 214 13 network network NN cord-292559-b21j9sf3 214 14 has have VBZ cord-292559-b21j9sf3 214 15 been be VBN cord-292559-b21j9sf3 214 16 associated associate VBN cord-292559-b21j9sf3 214 17 with with IN cord-292559-b21j9sf3 214 18 higher high JJR cord-292559-b21j9sf3 214 19 PLEs ple NNS cord-292559-b21j9sf3 214 20 , , , cord-292559-b21j9sf3 214 21 while while IN cord-292559-b21j9sf3 214 22 disrupted disrupt VBD cord-292559-b21j9sf3 214 23 connectivity connectivity NN cord-292559-b21j9sf3 214 24 between between IN cord-292559-b21j9sf3 214 25 the the DT cord-292559-b21j9sf3 214 26 CON con NN cord-292559-b21j9sf3 214 27 and and CC cord-292559-b21j9sf3 214 28 the the DT cord-292559-b21j9sf3 214 29 striatum striatum NN cord-292559-b21j9sf3 214 30 has have VBZ cord-292559-b21j9sf3 214 31 been be VBN cord-292559-b21j9sf3 214 32 associated associate VBN cord-292559-b21j9sf3 214 33 with with IN cord-292559-b21j9sf3 214 34 anhedonia anhedonia NN cord-292559-b21j9sf3 214 35 . . . cord-292559-b21j9sf3 215 1 It -PRON- PRP cord-292559-b21j9sf3 215 2 will will MD cord-292559-b21j9sf3 215 3 be be VB cord-292559-b21j9sf3 215 4 critical critical JJ cord-292559-b21j9sf3 215 5 to to TO cord-292559-b21j9sf3 215 6 determine determine VB cord-292559-b21j9sf3 215 7 whether whether IN cord-292559-b21j9sf3 215 8 these these DT cord-292559-b21j9sf3 215 9 similarities similarity NNS cord-292559-b21j9sf3 215 10 and and CC cord-292559-b21j9sf3 215 11 dissociations dissociation NNS cord-292559-b21j9sf3 215 12 remain remain VBP cord-292559-b21j9sf3 215 13 over over IN cord-292559-b21j9sf3 215 14 the the DT cord-292559-b21j9sf3 215 15 course course NN cord-292559-b21j9sf3 215 16 of of IN cord-292559-b21j9sf3 215 17 development development NN cord-292559-b21j9sf3 215 18 or or CC cord-292559-b21j9sf3 215 19 whether whether IN cord-292559-b21j9sf3 215 20 the the DT cord-292559-b21j9sf3 215 21 patterns pattern NNS cord-292559-b21j9sf3 215 22 of of IN cord-292559-b21j9sf3 215 23 disrupted disrupt VBN cord-292559-b21j9sf3 215 24 brain brain NN cord-292559-b21j9sf3 215 25 structure structure NN cord-292559-b21j9sf3 215 26 , , , cord-292559-b21j9sf3 215 27 function function NN cord-292559-b21j9sf3 215 28 and and CC cord-292559-b21j9sf3 215 29 connectivity connectivity NN cord-292559-b21j9sf3 215 30 evolve evolve VBP cord-292559-b21j9sf3 215 31 throughout throughout IN cord-292559-b21j9sf3 215 32 development development NN cord-292559-b21j9sf3 215 33 . . . cord-292559-b21j9sf3 216 1 Challenges challenge NNS cord-292559-b21j9sf3 216 2 and and CC cord-292559-b21j9sf3 216 3 opportunities opportunity NNS cord-292559-b21j9sf3 216 4 of of IN cord-292559-b21j9sf3 216 5 the the DT cord-292559-b21j9sf3 216 6 ABCD ABCD NNP cord-292559-b21j9sf3 216 7 Study Study NNP cord-292559-b21j9sf3 216 8 Challenges challenge NNS cord-292559-b21j9sf3 216 9 . . . cord-292559-b21j9sf3 217 1 One one CD cord-292559-b21j9sf3 217 2 challenge challenge NN cord-292559-b21j9sf3 217 3 the the DT cord-292559-b21j9sf3 217 4 ABCD ABCD NNP cord-292559-b21j9sf3 217 5 Study Study NNP cord-292559-b21j9sf3 217 6 has have VBZ cord-292559-b21j9sf3 217 7 encountered encounter VBN cord-292559-b21j9sf3 217 8 is be VBZ cord-292559-b21j9sf3 217 9 that that IN cord-292559-b21j9sf3 217 10 given give VBN cord-292559-b21j9sf3 217 11 data data NN cord-292559-b21j9sf3 217 12 is be VBZ cord-292559-b21j9sf3 217 13 open open JJ cord-292559-b21j9sf3 217 14 access access NN cord-292559-b21j9sf3 217 15 , , , cord-292559-b21j9sf3 217 16 multiple multiple JJ cord-292559-b21j9sf3 217 17 groups group NNS cord-292559-b21j9sf3 217 18 can can MD cord-292559-b21j9sf3 217 19 publish publish VB cord-292559-b21j9sf3 217 20 the the DT cord-292559-b21j9sf3 217 21 same same JJ cord-292559-b21j9sf3 217 22 or or CC cord-292559-b21j9sf3 217 23 very very RB cord-292559-b21j9sf3 217 24 similar similar JJ cord-292559-b21j9sf3 217 25 articles article NNS cord-292559-b21j9sf3 217 26 . . . cord-292559-b21j9sf3 218 1 Although although IN cord-292559-b21j9sf3 218 2 members member NNS cord-292559-b21j9sf3 218 3 of of IN cord-292559-b21j9sf3 218 4 the the DT cord-292559-b21j9sf3 218 5 ABCD ABCD NNP cord-292559-b21j9sf3 218 6 Consortium Consortium NNP cord-292559-b21j9sf3 218 7 are be VBP cord-292559-b21j9sf3 218 8 encouraged encourage VBN cord-292559-b21j9sf3 218 9 to to TO cord-292559-b21j9sf3 218 10 publish publish VB cord-292559-b21j9sf3 218 11 research research NN cord-292559-b21j9sf3 218 12 proposals proposal NNS cord-292559-b21j9sf3 218 13 on on IN cord-292559-b21j9sf3 218 14 the the DT cord-292559-b21j9sf3 218 15 internal internal JJ cord-292559-b21j9sf3 218 16 ABCD ABCD NNP cord-292559-b21j9sf3 218 17 Study Study NNP cord-292559-b21j9sf3 218 18 site site NN cord-292559-b21j9sf3 218 19 , , , cord-292559-b21j9sf3 218 20 this this DT cord-292559-b21j9sf3 218 21 information information NN cord-292559-b21j9sf3 218 22 is be VBZ cord-292559-b21j9sf3 218 23 not not RB cord-292559-b21j9sf3 218 24 available available JJ cord-292559-b21j9sf3 218 25 to to IN cord-292559-b21j9sf3 218 26 the the DT cord-292559-b21j9sf3 218 27 public public NN cord-292559-b21j9sf3 218 28 . . . cord-292559-b21j9sf3 219 1 Other other JJ cord-292559-b21j9sf3 219 2 challenges challenge NNS cord-292559-b21j9sf3 219 3 for for IN cord-292559-b21j9sf3 219 4 large large JJ cord-292559-b21j9sf3 219 5 - - HYPH cord-292559-b21j9sf3 219 6 scale scale NN cord-292559-b21j9sf3 219 7 studies study NNS cord-292559-b21j9sf3 219 8 in in IN cord-292559-b21j9sf3 219 9 general general JJ cord-292559-b21j9sf3 219 10 include include VBP cord-292559-b21j9sf3 219 11 retaining retain VBG cord-292559-b21j9sf3 219 12 subjects subject NNS cord-292559-b21j9sf3 219 13 followed follow VBN cord-292559-b21j9sf3 219 14 across across IN cord-292559-b21j9sf3 219 15 a a DT cord-292559-b21j9sf3 219 16 decade decade NN cord-292559-b21j9sf3 219 17 and and CC cord-292559-b21j9sf3 219 18 potential potential JJ cord-292559-b21j9sf3 219 19 biases bias NNS cord-292559-b21j9sf3 219 20 in in IN cord-292559-b21j9sf3 219 21 drop drop NN cord-292559-b21j9sf3 219 22 - - HYPH cord-292559-b21j9sf3 219 23 out out RP cord-292559-b21j9sf3 219 24 rates rate NNS cord-292559-b21j9sf3 219 25 ( ( -LRB- cord-292559-b21j9sf3 219 26 e.g. e.g. RB cord-292559-b21j9sf3 219 27 , , , cord-292559-b21j9sf3 219 28 lower low JJR cord-292559-b21j9sf3 219 29 SES SES NNP cord-292559-b21j9sf3 219 30 populations population NNS cord-292559-b21j9sf3 219 31 ) ) -RRB- cord-292559-b21j9sf3 219 32 . . . cord-292559-b21j9sf3 220 1 The the DT cord-292559-b21j9sf3 220 2 ABCD ABCD NNP cord-292559-b21j9sf3 220 3 Study Study NNP cord-292559-b21j9sf3 220 4 has have VBZ cord-292559-b21j9sf3 220 5 attempted attempt VBN cord-292559-b21j9sf3 220 6 to to TO cord-292559-b21j9sf3 220 7 mitigate mitigate VB cord-292559-b21j9sf3 220 8 these these DT cord-292559-b21j9sf3 220 9 challenges challenge NNS cord-292559-b21j9sf3 220 10 by by IN cord-292559-b21j9sf3 220 11 developing develop VBG cord-292559-b21j9sf3 220 12 strategies strategy NNS cord-292559-b21j9sf3 220 13 to to TO cord-292559-b21j9sf3 220 14 maintain maintain VB cord-292559-b21j9sf3 220 15 rapport rapport NN cord-292559-b21j9sf3 220 16 , , , cord-292559-b21j9sf3 220 17 keeping keep VBG cord-292559-b21j9sf3 220 18 detailed detailed JJ cord-292559-b21j9sf3 220 19 current current JJ cord-292559-b21j9sf3 220 20 locator locator NN cord-292559-b21j9sf3 220 21 information information NN cord-292559-b21j9sf3 220 22 , , , cord-292559-b21j9sf3 220 23 offering offer VBG cord-292559-b21j9sf3 220 24 participation participation NN cord-292559-b21j9sf3 220 25 - - HYPH cord-292559-b21j9sf3 220 26 related relate VBN cord-292559-b21j9sf3 220 27 resources resource NNS cord-292559-b21j9sf3 220 28 ( ( -LRB- cord-292559-b21j9sf3 220 29 e.g. e.g. RB cord-292559-b21j9sf3 220 30 , , , cord-292559-b21j9sf3 220 31 travel travel NN cord-292559-b21j9sf3 220 32 assistance assistance NN cord-292559-b21j9sf3 220 33 ) ) -RRB- cord-292559-b21j9sf3 220 34 , , , cord-292559-b21j9sf3 220 35 and and CC cord-292559-b21j9sf3 220 36 monitoring monitor VBG cord-292559-b21j9sf3 220 37 retention retention NN cord-292559-b21j9sf3 220 38 during during IN cord-292559-b21j9sf3 220 39 bi bi JJ cord-292559-b21j9sf3 220 40 - - JJ cord-292559-b21j9sf3 220 41 monthly monthly JJ cord-292559-b21j9sf3 220 42 meetings meeting NNS cord-292559-b21j9sf3 220 43 [ [ -LRB- cord-292559-b21j9sf3 220 44 16 16 CD cord-292559-b21j9sf3 220 45 ] ] -RRB- cord-292559-b21j9sf3 220 46 . . . cord-292559-b21j9sf3 221 1 Effect effect NN cord-292559-b21j9sf3 221 2 sizes size NNS cord-292559-b21j9sf3 221 3 : : : cord-292559-b21j9sf3 222 1 what what WP cord-292559-b21j9sf3 222 2 to to TO cord-292559-b21j9sf3 222 3 expect expect VB cord-292559-b21j9sf3 222 4 . . . cord-292559-b21j9sf3 223 1 As as IN cord-292559-b21j9sf3 223 2 outlined outline VBN cord-292559-b21j9sf3 223 3 in in IN cord-292559-b21j9sf3 223 4 a a DT cord-292559-b21j9sf3 223 5 recent recent JJ cord-292559-b21j9sf3 223 6 paper paper NN cord-292559-b21j9sf3 223 7 [ [ -LRB- cord-292559-b21j9sf3 223 8 65 65 CD cord-292559-b21j9sf3 223 9 ] ] -RRB- cord-292559-b21j9sf3 223 10 , , , cord-292559-b21j9sf3 223 11 large large JJ cord-292559-b21j9sf3 223 12 sample sample NN cord-292559-b21j9sf3 223 13 sizes size NNS cord-292559-b21j9sf3 223 14 are be VBP cord-292559-b21j9sf3 223 15 necessary necessary JJ cord-292559-b21j9sf3 223 16 to to TO cord-292559-b21j9sf3 223 17 examine examine VB cord-292559-b21j9sf3 223 18 the the DT cord-292559-b21j9sf3 223 19 earliest early JJS cord-292559-b21j9sf3 223 20 markers marker NNS cord-292559-b21j9sf3 223 21 and and CC cord-292559-b21j9sf3 223 22 mechanisms mechanism NNS cord-292559-b21j9sf3 223 23 of of IN cord-292559-b21j9sf3 223 24 disease disease NN cord-292559-b21j9sf3 223 25 processes process NNS cord-292559-b21j9sf3 223 26 , , , cord-292559-b21j9sf3 223 27 as as IN cord-292559-b21j9sf3 223 28 these these DT cord-292559-b21j9sf3 223 29 markers marker NNS cord-292559-b21j9sf3 223 30 are be VBP cord-292559-b21j9sf3 223 31 likely likely JJ cord-292559-b21j9sf3 223 32 to to TO cord-292559-b21j9sf3 223 33 be be VB cord-292559-b21j9sf3 223 34 more more RBR cord-292559-b21j9sf3 223 35 subtle subtle JJ cord-292559-b21j9sf3 223 36 early early RB cord-292559-b21j9sf3 223 37 in in IN cord-292559-b21j9sf3 223 38 the the DT cord-292559-b21j9sf3 223 39 course course NN cord-292559-b21j9sf3 223 40 of of IN cord-292559-b21j9sf3 223 41 illness illness NN cord-292559-b21j9sf3 223 42 . . . cord-292559-b21j9sf3 224 1 An an DT cord-292559-b21j9sf3 224 2 opportunity opportunity NN cord-292559-b21j9sf3 224 3 that that WDT cord-292559-b21j9sf3 224 4 also also RB cord-292559-b21j9sf3 224 5 presents present VBZ cord-292559-b21j9sf3 224 6 a a DT cord-292559-b21j9sf3 224 7 challenge challenge NN cord-292559-b21j9sf3 224 8 is be VBZ cord-292559-b21j9sf3 224 9 these these DT cord-292559-b21j9sf3 224 10 large large JJ cord-292559-b21j9sf3 224 11 data datum NNS cord-292559-b21j9sf3 224 12 sets set NNS cord-292559-b21j9sf3 224 13 enable enable VBP cord-292559-b21j9sf3 224 14 the the DT cord-292559-b21j9sf3 224 15 detection detection NN cord-292559-b21j9sf3 224 16 of of IN cord-292559-b21j9sf3 224 17 very very RB cord-292559-b21j9sf3 224 18 subtle subtle JJ cord-292559-b21j9sf3 224 19 effects effect NNS cord-292559-b21j9sf3 224 20 not not RB cord-292559-b21j9sf3 224 21 generally generally RB cord-292559-b21j9sf3 224 22 detectable detectable JJ cord-292559-b21j9sf3 224 23 in in IN cord-292559-b21j9sf3 224 24 smaller small JJR cord-292559-b21j9sf3 224 25 sample sample NN cord-292559-b21j9sf3 224 26 studies study NNS cord-292559-b21j9sf3 224 27 . . . cord-292559-b21j9sf3 225 1 The the DT cord-292559-b21j9sf3 225 2 challenge challenge NN cord-292559-b21j9sf3 225 3 of of IN cord-292559-b21j9sf3 225 4 detecting detect VBG cord-292559-b21j9sf3 225 5 small small JJ cord-292559-b21j9sf3 225 6 effects effect NNS cord-292559-b21j9sf3 225 7 is be VBZ cord-292559-b21j9sf3 225 8 determining determine VBG cord-292559-b21j9sf3 225 9 whether whether IN cord-292559-b21j9sf3 225 10 very very RB cord-292559-b21j9sf3 225 11 small small JJ cord-292559-b21j9sf3 225 12 effects effect NNS cord-292559-b21j9sf3 225 13 ( ( -LRB- cord-292559-b21j9sf3 225 14 i.e. i.e. FW cord-292559-b21j9sf3 225 15 , , , cord-292559-b21j9sf3 225 16 < < XX cord-292559-b21j9sf3 225 17 1 1 CD cord-292559-b21j9sf3 225 18 % % NN cord-292559-b21j9sf3 225 19 of of IN cord-292559-b21j9sf3 225 20 variance variance NN cord-292559-b21j9sf3 225 21 explained explain VBD cord-292559-b21j9sf3 225 22 ) ) -RRB- cord-292559-b21j9sf3 225 23 are be VBP cord-292559-b21j9sf3 225 24 practically practically RB cord-292559-b21j9sf3 225 25 meaningful meaningful JJ cord-292559-b21j9sf3 225 26 [ [ -LRB- cord-292559-b21j9sf3 225 27 65 65 CD cord-292559-b21j9sf3 225 28 ] ] -RRB- cord-292559-b21j9sf3 225 29 . . . cord-292559-b21j9sf3 226 1 Large large JJ cord-292559-b21j9sf3 226 2 well well RB cord-292559-b21j9sf3 226 3 - - HYPH cord-292559-b21j9sf3 226 4 powered power VBN cord-292559-b21j9sf3 226 5 samples sample NNS cord-292559-b21j9sf3 226 6 enable enable VBP cord-292559-b21j9sf3 226 7 the the DT cord-292559-b21j9sf3 226 8 detection detection NN cord-292559-b21j9sf3 226 9 of of IN cord-292559-b21j9sf3 226 10 the the DT cord-292559-b21j9sf3 226 11 earliest early JJS cord-292559-b21j9sf3 226 12 subtle subtle JJ cord-292559-b21j9sf3 226 13 associations association NNS cord-292559-b21j9sf3 226 14 between between IN cord-292559-b21j9sf3 226 15 predictor predictor NN cord-292559-b21j9sf3 226 16 and and CC cord-292559-b21j9sf3 226 17 outcome outcome NN cord-292559-b21j9sf3 226 18 of of IN cord-292559-b21j9sf3 226 19 small small JJ cord-292559-b21j9sf3 226 20 effect effect NN cord-292559-b21j9sf3 226 21 , , , cord-292559-b21j9sf3 226 22 prior prior RB cord-292559-b21j9sf3 226 23 to to IN cord-292559-b21j9sf3 226 24 larger large JJR cord-292559-b21j9sf3 226 25 effect effect NN cord-292559-b21j9sf3 226 26 size size NN cord-292559-b21j9sf3 226 27 associations association NNS cord-292559-b21j9sf3 226 28 that that WDT cord-292559-b21j9sf3 226 29 may may MD cord-292559-b21j9sf3 226 30 emerge emerge VB cord-292559-b21j9sf3 226 31 later later RB cord-292559-b21j9sf3 226 32 in in IN cord-292559-b21j9sf3 226 33 the the DT cord-292559-b21j9sf3 226 34 disease disease NN cord-292559-b21j9sf3 226 35 process process NN cord-292559-b21j9sf3 226 36 . . . cord-292559-b21j9sf3 227 1 For for IN cord-292559-b21j9sf3 227 2 example example NN cord-292559-b21j9sf3 227 3 , , , cord-292559-b21j9sf3 227 4 estimating estimate VBG cord-292559-b21j9sf3 227 5 the the DT cord-292559-b21j9sf3 227 6 prevalence prevalence NN cord-292559-b21j9sf3 227 7 of of IN cord-292559-b21j9sf3 227 8 major major JJ cord-292559-b21j9sf3 227 9 depressive depressive JJ cord-292559-b21j9sf3 227 10 disorder disorder NN cord-292559-b21j9sf3 227 11 at at IN cord-292559-b21j9sf3 227 12 2 2 CD cord-292559-b21j9sf3 227 13 % % NN cord-292559-b21j9sf3 227 14 in in IN cord-292559-b21j9sf3 227 15 middle middle JJ cord-292559-b21j9sf3 227 16 childhood childhood NN cord-292559-b21j9sf3 227 17 [ [ -LRB- cord-292559-b21j9sf3 227 18 66 66 CD cord-292559-b21j9sf3 227 19 ] ] -RRB- cord-292559-b21j9sf3 227 20 , , , cord-292559-b21j9sf3 227 21 the the DT cord-292559-b21j9sf3 227 22 ABCD ABCD NNP cord-292559-b21j9sf3 227 23 Study Study NNP cord-292559-b21j9sf3 227 24 's 's POS cord-292559-b21j9sf3 227 25 power power NN cord-292559-b21j9sf3 227 26 = = SYM cord-292559-b21j9sf3 227 27 .90 .90 NFP cord-292559-b21j9sf3 227 28 to to TO cord-292559-b21j9sf3 227 29 detect detect VB cord-292559-b21j9sf3 227 30 small small JJ cord-292559-b21j9sf3 227 31 effect effect NN cord-292559-b21j9sf3 227 32 ( ( -LRB- cord-292559-b21j9sf3 227 33 Cohen Cohen NNP cord-292559-b21j9sf3 227 34 's 's POS cord-292559-b21j9sf3 227 35 d d NN cord-292559-b21j9sf3 227 36 = = SYM cord-292559-b21j9sf3 227 37 .30 .30 NFP cord-292559-b21j9sf3 227 38 ) ) -RRB- cord-292559-b21j9sf3 227 39 differences difference NNS cord-292559-b21j9sf3 227 40 between between IN cord-292559-b21j9sf3 227 41 individuals individual NNS cord-292559-b21j9sf3 227 42 with with IN cord-292559-b21j9sf3 227 43 major major JJ cord-292559-b21j9sf3 227 44 depressive depressive JJ cord-292559-b21j9sf3 227 45 disorder disorder NN cord-292559-b21j9sf3 227 46 and and CC cord-292559-b21j9sf3 227 47 controls control NNS cord-292559-b21j9sf3 227 48 . . . cord-292559-b21j9sf3 228 1 Additionally additionally RB cord-292559-b21j9sf3 228 2 , , , cord-292559-b21j9sf3 228 3 it -PRON- PRP cord-292559-b21j9sf3 228 4 is be VBZ cord-292559-b21j9sf3 228 5 entirely entirely RB cord-292559-b21j9sf3 228 6 expected expect VBN cord-292559-b21j9sf3 228 7 that that IN cord-292559-b21j9sf3 228 8 many many JJ cord-292559-b21j9sf3 228 9 of of IN cord-292559-b21j9sf3 228 10 these these DT cord-292559-b21j9sf3 228 11 analyses analysis NNS cord-292559-b21j9sf3 228 12 will will MD cord-292559-b21j9sf3 228 13 produce produce VB cord-292559-b21j9sf3 228 14 small small JJ cord-292559-b21j9sf3 228 15 effects effect NNS cord-292559-b21j9sf3 228 16 . . . cord-292559-b21j9sf3 229 1 First first RB cord-292559-b21j9sf3 229 2 , , , cord-292559-b21j9sf3 229 3 baseline baseline JJ cord-292559-b21j9sf3 229 4 ABCD ABCD NNP cord-292559-b21j9sf3 229 5 Study Study NNP cord-292559-b21j9sf3 229 6 analyses analysis NNS cord-292559-b21j9sf3 229 7 are be VBP cord-292559-b21j9sf3 229 8 examining examine VBG cord-292559-b21j9sf3 229 9 early early JJ cord-292559-b21j9sf3 229 10 risk risk NN cord-292559-b21j9sf3 229 11 factors factor NNS cord-292559-b21j9sf3 229 12 of of IN cord-292559-b21j9sf3 229 13 negative negative JJ cord-292559-b21j9sf3 229 14 mental mental JJ cord-292559-b21j9sf3 229 15 and and CC cord-292559-b21j9sf3 229 16 physical physical JJ cord-292559-b21j9sf3 229 17 health health NN cord-292559-b21j9sf3 229 18 outcomes outcome NNS cord-292559-b21j9sf3 229 19 in in IN cord-292559-b21j9sf3 229 20 a a DT cord-292559-b21j9sf3 229 21 generally generally RB cord-292559-b21j9sf3 229 22 high high JJ cord-292559-b21j9sf3 229 23 functioning function VBG cord-292559-b21j9sf3 229 24 non non JJ cord-292559-b21j9sf3 229 25 - - JJ cord-292559-b21j9sf3 229 26 clinical clinical JJ cord-292559-b21j9sf3 229 27 sample sample NN cord-292559-b21j9sf3 229 28 prior prior RB cord-292559-b21j9sf3 229 29 to to IN cord-292559-b21j9sf3 229 30 entering enter VBG cord-292559-b21j9sf3 229 31 the the DT cord-292559-b21j9sf3 229 32 age age NN cord-292559-b21j9sf3 229 33 range range NN cord-292559-b21j9sf3 229 34 of of IN cord-292559-b21j9sf3 229 35 highest high JJS cord-292559-b21j9sf3 229 36 risk risk NN cord-292559-b21j9sf3 229 37 for for IN cord-292559-b21j9sf3 229 38 a a DT cord-292559-b21j9sf3 229 39 number number NN cord-292559-b21j9sf3 229 40 of of IN cord-292559-b21j9sf3 229 41 negative negative JJ cord-292559-b21j9sf3 229 42 outcomes outcome NNS cord-292559-b21j9sf3 229 43 ( ( -LRB- cord-292559-b21j9sf3 229 44 e.g. e.g. RB cord-292559-b21j9sf3 229 45 , , , cord-292559-b21j9sf3 229 46 psychosis psychosis NN cord-292559-b21j9sf3 229 47 spectrum spectrum NN cord-292559-b21j9sf3 229 48 symptoms symptom NNS cord-292559-b21j9sf3 229 49 ) ) -RRB- cord-292559-b21j9sf3 229 50 [ [ -LRB- cord-292559-b21j9sf3 229 51 67 67 CD cord-292559-b21j9sf3 229 52 ] ] -RRB- cord-292559-b21j9sf3 229 53 . . . cord-292559-b21j9sf3 230 1 Furthermore furthermore RB cord-292559-b21j9sf3 230 2 , , , cord-292559-b21j9sf3 230 3 since since IN cord-292559-b21j9sf3 230 4 the the DT cord-292559-b21j9sf3 230 5 ABCD ABCD NNP cord-292559-b21j9sf3 230 6 Study Study NNP cord-292559-b21j9sf3 230 7 is be VBZ cord-292559-b21j9sf3 230 8 an an DT cord-292559-b21j9sf3 230 9 epidemiologically epidemiologically RB cord-292559-b21j9sf3 230 10 informed informed JJ cord-292559-b21j9sf3 230 11 study study NN cord-292559-b21j9sf3 230 12 with with IN cord-292559-b21j9sf3 230 13 a a DT cord-292559-b21j9sf3 230 14 demographically demographically RB cord-292559-b21j9sf3 230 15 diverse diverse JJ cord-292559-b21j9sf3 230 16 sample sample NN cord-292559-b21j9sf3 230 17 [ [ -LRB- cord-292559-b21j9sf3 230 18 14 14 CD cord-292559-b21j9sf3 230 19 ] ] -RRB- cord-292559-b21j9sf3 230 20 , , , cord-292559-b21j9sf3 230 21 rather rather RB cord-292559-b21j9sf3 230 22 than than IN cord-292559-b21j9sf3 230 23 a a DT cord-292559-b21j9sf3 230 24 convenience convenience NN cord-292559-b21j9sf3 230 25 or or CC cord-292559-b21j9sf3 230 26 clinical clinical JJ cord-292559-b21j9sf3 230 27 sample sample NN cord-292559-b21j9sf3 230 28 , , , cord-292559-b21j9sf3 230 29 it -PRON- PRP cord-292559-b21j9sf3 230 30 is be VBZ cord-292559-b21j9sf3 230 31 expected expect VBN cord-292559-b21j9sf3 230 32 that that IN cord-292559-b21j9sf3 230 33 effect effect NN cord-292559-b21j9sf3 230 34 sizes size NNS cord-292559-b21j9sf3 230 35 will will MD cord-292559-b21j9sf3 230 36 be be VB cord-292559-b21j9sf3 230 37 more more RBR cord-292559-b21j9sf3 230 38 " " `` cord-292559-b21j9sf3 230 39 diluted diluted JJ cord-292559-b21j9sf3 230 40 " " '' cord-292559-b21j9sf3 230 41 as as IN cord-292559-b21j9sf3 230 42 they -PRON- PRP cord-292559-b21j9sf3 230 43 are be VBP cord-292559-b21j9sf3 230 44 being be VBG cord-292559-b21j9sf3 230 45 examined examine VBN cord-292559-b21j9sf3 230 46 in in IN cord-292559-b21j9sf3 230 47 the the DT cord-292559-b21j9sf3 230 48 context context NN cord-292559-b21j9sf3 230 49 of of IN cord-292559-b21j9sf3 230 50 a a DT cord-292559-b21j9sf3 230 51 complex complex JJ cord-292559-b21j9sf3 230 52 set set NN cord-292559-b21j9sf3 230 53 of of IN cord-292559-b21j9sf3 230 54 contextual contextual JJ cord-292559-b21j9sf3 230 55 and and CC cord-292559-b21j9sf3 230 56 background background NN cord-292559-b21j9sf3 230 57 variables variable NNS cord-292559-b21j9sf3 230 58 . . . cord-292559-b21j9sf3 231 1 Further further RB cord-292559-b21j9sf3 231 2 , , , cord-292559-b21j9sf3 231 3 our -PRON- PRP$ cord-292559-b21j9sf3 231 4 expectations expectation NNS cord-292559-b21j9sf3 231 5 for for IN cord-292559-b21j9sf3 231 6 effect effect NN cord-292559-b21j9sf3 231 7 sizes size NNS cord-292559-b21j9sf3 231 8 are be VBP cord-292559-b21j9sf3 231 9 likely likely RB cord-292559-b21j9sf3 231 10 biased biased JJ cord-292559-b21j9sf3 231 11 , , , cord-292559-b21j9sf3 231 12 as as IN cord-292559-b21j9sf3 231 13 it -PRON- PRP cord-292559-b21j9sf3 231 14 is be VBZ cord-292559-b21j9sf3 231 15 known know VBN cord-292559-b21j9sf3 231 16 that that IN cord-292559-b21j9sf3 231 17 underpowered underpowered JJ cord-292559-b21j9sf3 231 18 studies study NNS cord-292559-b21j9sf3 231 19 overestimate overestimate VBP cord-292559-b21j9sf3 231 20 effect effect NN cord-292559-b21j9sf3 231 21 sizes size NNS cord-292559-b21j9sf3 231 22 [ [ -LRB- cord-292559-b21j9sf3 231 23 68 68 CD cord-292559-b21j9sf3 231 24 , , , cord-292559-b21j9sf3 231 25 69 69 CD cord-292559-b21j9sf3 231 26 ] ] -RRB- cord-292559-b21j9sf3 231 27 . . . cord-292559-b21j9sf3 232 1 Thus thus RB cord-292559-b21j9sf3 232 2 , , , cord-292559-b21j9sf3 232 3 the the DT cord-292559-b21j9sf3 232 4 field field NN cord-292559-b21j9sf3 232 5 is be VBZ cord-292559-b21j9sf3 232 6 in in IN cord-292559-b21j9sf3 232 7 need need NN cord-292559-b21j9sf3 232 8 of of IN cord-292559-b21j9sf3 232 9 well well RB cord-292559-b21j9sf3 232 10 - - HYPH cord-292559-b21j9sf3 232 11 powered power VBN cord-292559-b21j9sf3 232 12 studies study NNS cord-292559-b21j9sf3 232 13 , , , cord-292559-b21j9sf3 232 14 especially especially RB cord-292559-b21j9sf3 232 15 in in IN cord-292559-b21j9sf3 232 16 neuroimaging neuroimage VBG cord-292559-b21j9sf3 232 17 analyses analysis NNS cord-292559-b21j9sf3 232 18 , , , cord-292559-b21j9sf3 232 19 to to TO cord-292559-b21j9sf3 232 20 better better RB cord-292559-b21j9sf3 232 21 understand understand VB cord-292559-b21j9sf3 232 22 the the DT cord-292559-b21j9sf3 232 23 expected expect VBN cord-292559-b21j9sf3 232 24 effect effect NN cord-292559-b21j9sf3 232 25 sizes size NNS cord-292559-b21j9sf3 232 26 for for IN cord-292559-b21j9sf3 232 27 these these DT cord-292559-b21j9sf3 232 28 associations association NNS cord-292559-b21j9sf3 232 29 in in IN cord-292559-b21j9sf3 232 30 the the DT cord-292559-b21j9sf3 232 31 general general JJ cord-292559-b21j9sf3 232 32 population population NN cord-292559-b21j9sf3 232 33 . . . cord-292559-b21j9sf3 233 1 Robust robust JJ cord-292559-b21j9sf3 233 2 exploratory exploratory JJ cord-292559-b21j9sf3 233 3 analyses analysis NNS cord-292559-b21j9sf3 233 4 . . . cord-292559-b21j9sf3 234 1 Another another DT cord-292559-b21j9sf3 234 2 opportunity opportunity NN cord-292559-b21j9sf3 234 3 that that IN cord-292559-b21j9sf3 234 4 the the DT cord-292559-b21j9sf3 234 5 large large JJ cord-292559-b21j9sf3 234 6 sample sample NN cord-292559-b21j9sf3 234 7 size size NN cord-292559-b21j9sf3 234 8 of of IN cord-292559-b21j9sf3 234 9 the the DT cord-292559-b21j9sf3 234 10 ABCD ABCD NNP cord-292559-b21j9sf3 234 11 Study Study NNP cord-292559-b21j9sf3 234 12 offers offer VBZ cord-292559-b21j9sf3 234 13 is be VBZ cord-292559-b21j9sf3 234 14 the the DT cord-292559-b21j9sf3 234 15 possibility possibility NN cord-292559-b21j9sf3 234 16 of of IN cord-292559-b21j9sf3 234 17 conducting conduct VBG cord-292559-b21j9sf3 234 18 exploratory exploratory JJ cord-292559-b21j9sf3 234 19 analyses analysis NNS cord-292559-b21j9sf3 234 20 for for IN cord-292559-b21j9sf3 234 21 questions question NNS cord-292559-b21j9sf3 234 22 with with IN cord-292559-b21j9sf3 234 23 no no DT cord-292559-b21j9sf3 234 24 strong strong JJ cord-292559-b21j9sf3 234 25 a a DT cord-292559-b21j9sf3 234 26 priori priori FW cord-292559-b21j9sf3 234 27 hypotheses hypothesis NNS cord-292559-b21j9sf3 234 28 . . . cord-292559-b21j9sf3 235 1 As as IN cord-292559-b21j9sf3 235 2 the the DT cord-292559-b21j9sf3 235 3 NIMH NIMH NNP cord-292559-b21j9sf3 235 4 has have VBZ cord-292559-b21j9sf3 235 5 recently recently RB cord-292559-b21j9sf3 235 6 advocated advocate VBN cord-292559-b21j9sf3 235 7 [ [ -LRB- cord-292559-b21j9sf3 235 8 70 70 CD cord-292559-b21j9sf3 235 9 , , , cord-292559-b21j9sf3 235 10 71 71 CD cord-292559-b21j9sf3 235 11 ] ] -RRB- cord-292559-b21j9sf3 235 12 , , , cord-292559-b21j9sf3 235 13 it -PRON- PRP cord-292559-b21j9sf3 235 14 will will MD cord-292559-b21j9sf3 235 15 be be VB cord-292559-b21j9sf3 235 16 critical critical JJ cord-292559-b21j9sf3 235 17 to to TO cord-292559-b21j9sf3 235 18 implement implement VB cord-292559-b21j9sf3 235 19 robust robust JJ cord-292559-b21j9sf3 235 20 and and CC cord-292559-b21j9sf3 235 21 rigorous rigorous JJ cord-292559-b21j9sf3 235 22 practices practice NNS cord-292559-b21j9sf3 235 23 for for IN cord-292559-b21j9sf3 235 24 conducting conduct VBG cord-292559-b21j9sf3 235 25 exploratory exploratory JJ cord-292559-b21j9sf3 235 26 analyses analysis NNS cord-292559-b21j9sf3 235 27 . . . cord-292559-b21j9sf3 236 1 First first RB cord-292559-b21j9sf3 236 2 , , , cord-292559-b21j9sf3 236 3 we -PRON- PRP cord-292559-b21j9sf3 236 4 suggest suggest VBP cord-292559-b21j9sf3 236 5 utilizing utilize VBG cord-292559-b21j9sf3 236 6 discovery discovery NN cord-292559-b21j9sf3 236 7 and and CC cord-292559-b21j9sf3 236 8 replication replication NN cord-292559-b21j9sf3 236 9 datasets dataset NNS cord-292559-b21j9sf3 236 10 . . . cord-292559-b21j9sf3 237 1 Researchers researcher NNS cord-292559-b21j9sf3 237 2 conducting conduct VBG cord-292559-b21j9sf3 237 3 exploratory exploratory JJ cord-292559-b21j9sf3 237 4 analyses analysis NNS cord-292559-b21j9sf3 237 5 can can MD cord-292559-b21j9sf3 237 6 conduct conduct VB cord-292559-b21j9sf3 237 7 analyses analysis NNS cord-292559-b21j9sf3 237 8 on on IN cord-292559-b21j9sf3 237 9 the the DT cord-292559-b21j9sf3 237 10 discovery discovery NN cord-292559-b21j9sf3 237 11 dataset dataset NN cord-292559-b21j9sf3 237 12 , , , cord-292559-b21j9sf3 237 13 and and CC cord-292559-b21j9sf3 237 14 examine examine VB cord-292559-b21j9sf3 237 15 whether whether IN cord-292559-b21j9sf3 237 16 results result NNS cord-292559-b21j9sf3 237 17 replicate replicate VBP cord-292559-b21j9sf3 237 18 in in IN cord-292559-b21j9sf3 237 19 the the DT cord-292559-b21j9sf3 237 20 replication replication NN cord-292559-b21j9sf3 237 21 dataset dataset NN cord-292559-b21j9sf3 237 22 , , , cord-292559-b21j9sf3 237 23 a a DT cord-292559-b21j9sf3 237 24 technique technique NN cord-292559-b21j9sf3 237 25 used use VBN cord-292559-b21j9sf3 237 26 to to TO cord-292559-b21j9sf3 237 27 improve improve VB cord-292559-b21j9sf3 237 28 the the DT cord-292559-b21j9sf3 237 29 replicability replicability NN cord-292559-b21j9sf3 237 30 of of IN cord-292559-b21j9sf3 237 31 GWAS GWAS NNP cord-292559-b21j9sf3 237 32 studies study NNS cord-292559-b21j9sf3 237 33 [ [ -LRB- cord-292559-b21j9sf3 237 34 72 72 CD cord-292559-b21j9sf3 237 35 ] ] -RRB- cord-292559-b21j9sf3 237 36 . . . cord-292559-b21j9sf3 238 1 Researchers researcher NNS cord-292559-b21j9sf3 238 2 can can MD cord-292559-b21j9sf3 238 3 match match VB cord-292559-b21j9sf3 238 4 these these DT cord-292559-b21j9sf3 238 5 datasets dataset NNS cord-292559-b21j9sf3 238 6 on on IN cord-292559-b21j9sf3 238 7 demographic demographic JJ cord-292559-b21j9sf3 238 8 variables variable NNS cord-292559-b21j9sf3 238 9 , , , cord-292559-b21j9sf3 238 10 including include VBG cord-292559-b21j9sf3 238 11 sex sex NN cord-292559-b21j9sf3 238 12 , , , cord-292559-b21j9sf3 238 13 race race NN cord-292559-b21j9sf3 238 14 , , , cord-292559-b21j9sf3 238 15 ethnicity ethnicity NN cord-292559-b21j9sf3 238 16 , , , cord-292559-b21j9sf3 238 17 and and CC cord-292559-b21j9sf3 238 18 age age NN cord-292559-b21j9sf3 238 19 . . . cord-292559-b21j9sf3 239 1 Given give VBN cord-292559-b21j9sf3 239 2 that that DT cord-292559-b21j9sf3 239 3 exploratory exploratory JJ cord-292559-b21j9sf3 239 4 analyses analysis NNS cord-292559-b21j9sf3 239 5 are be VBP cord-292559-b21j9sf3 239 6 prone prone JJ cord-292559-b21j9sf3 239 7 to to IN cord-292559-b21j9sf3 239 8 false false JJ cord-292559-b21j9sf3 239 9 positives positive NNS cord-292559-b21j9sf3 239 10 , , , cord-292559-b21j9sf3 239 11 first first RB cord-292559-b21j9sf3 239 12 examining examine VBG cord-292559-b21j9sf3 239 13 analyses analysis NNS cord-292559-b21j9sf3 239 14 in in IN cord-292559-b21j9sf3 239 15 a a DT cord-292559-b21j9sf3 239 16 discovery discovery NN cord-292559-b21j9sf3 239 17 dataset dataset NN cord-292559-b21j9sf3 239 18 and and CC cord-292559-b21j9sf3 239 19 then then RB cord-292559-b21j9sf3 239 20 testing test VBG cord-292559-b21j9sf3 239 21 any any DT cord-292559-b21j9sf3 239 22 findings finding NNS cord-292559-b21j9sf3 239 23 in in IN cord-292559-b21j9sf3 239 24 a a DT cord-292559-b21j9sf3 239 25 replication replication NN cord-292559-b21j9sf3 239 26 dataset dataset NN cord-292559-b21j9sf3 239 27 reduces reduce VBZ cord-292559-b21j9sf3 239 28 the the DT cord-292559-b21j9sf3 239 29 possibility possibility NN cord-292559-b21j9sf3 239 30 of of IN cord-292559-b21j9sf3 239 31 Type type NN cord-292559-b21j9sf3 239 32 I -PRON- PRP cord-292559-b21j9sf3 239 33 error error NN cord-292559-b21j9sf3 239 34 . . . cord-292559-b21j9sf3 240 1 Furthermore furthermore RB cord-292559-b21j9sf3 240 2 , , , cord-292559-b21j9sf3 240 3 to to IN cord-292559-b21j9sf3 240 4 the the DT cord-292559-b21j9sf3 240 5 extent extent NN cord-292559-b21j9sf3 240 6 that that IN cord-292559-b21j9sf3 240 7 it -PRON- PRP cord-292559-b21j9sf3 240 8 is be VBZ cord-292559-b21j9sf3 240 9 possible possible JJ cord-292559-b21j9sf3 240 10 , , , cord-292559-b21j9sf3 240 11 researchers researcher NNS cord-292559-b21j9sf3 240 12 should should MD cord-292559-b21j9sf3 240 13 specify specify VB cord-292559-b21j9sf3 240 14 hypotheses hypothesis NNS cord-292559-b21j9sf3 240 15 prior prior RB cord-292559-b21j9sf3 240 16 to to IN cord-292559-b21j9sf3 240 17 conducting conduct VBG cord-292559-b21j9sf3 240 18 analyses analysis NNS cord-292559-b21j9sf3 240 19 . . . cord-292559-b21j9sf3 241 1 Ideally ideally RB cord-292559-b21j9sf3 241 2 , , , cord-292559-b21j9sf3 241 3 researchers researcher NNS cord-292559-b21j9sf3 241 4 would would MD cord-292559-b21j9sf3 241 5 create create VB cord-292559-b21j9sf3 241 6 a a DT cord-292559-b21j9sf3 241 7 pre pre JJ cord-292559-b21j9sf3 241 8 - - NN cord-292559-b21j9sf3 241 9 registration registration NN cord-292559-b21j9sf3 242 1 or or CC cord-292559-b21j9sf3 242 2 even even RB cord-292559-b21j9sf3 242 3 a a DT cord-292559-b21j9sf3 242 4 registered registered JJ cord-292559-b21j9sf3 242 5 report report NN cord-292559-b21j9sf3 242 6 detailing detail VBG cord-292559-b21j9sf3 242 7 hypotheses hypothesis NNS cord-292559-b21j9sf3 242 8 and and CC cord-292559-b21j9sf3 242 9 analyses analysis NNS cord-292559-b21j9sf3 242 10 prior prior RB cord-292559-b21j9sf3 242 11 to to IN cord-292559-b21j9sf3 242 12 conducting conduct VBG cord-292559-b21j9sf3 242 13 analyses analysis NNS cord-292559-b21j9sf3 242 14 ( ( -LRB- cord-292559-b21j9sf3 242 15 https://cos.io/rr/ https://cos.io/rr/ NN cord-292559-b21j9sf3 242 16 ) ) -RRB- cord-292559-b21j9sf3 242 17 . . . cord-292559-b21j9sf3 243 1 Specifying specify VBG cord-292559-b21j9sf3 243 2 even even RB cord-292559-b21j9sf3 243 3 general general JJ cord-292559-b21j9sf3 243 4 hypotheses hypothesis NNS cord-292559-b21j9sf3 243 5 helps help VBZ cord-292559-b21j9sf3 243 6 frame frame VB cord-292559-b21j9sf3 243 7 the the DT cord-292559-b21j9sf3 243 8 results result NNS cord-292559-b21j9sf3 243 9 and and CC cord-292559-b21j9sf3 243 10 can can MD cord-292559-b21j9sf3 243 11 put put VB cord-292559-b21j9sf3 243 12 unexpected unexpected JJ cord-292559-b21j9sf3 243 13 results result NNS cord-292559-b21j9sf3 243 14 into into IN cord-292559-b21j9sf3 243 15 context context NN cord-292559-b21j9sf3 243 16 . . . cord-292559-b21j9sf3 244 1 Further further RB cord-292559-b21j9sf3 244 2 , , , cord-292559-b21j9sf3 244 3 preregistering preregistere VBG cord-292559-b21j9sf3 244 4 analysis analysis NN cord-292559-b21j9sf3 244 5 approaches approach NNS cord-292559-b21j9sf3 244 6 even even RB cord-292559-b21j9sf3 244 7 in in IN cord-292559-b21j9sf3 244 8 the the DT cord-292559-b21j9sf3 244 9 absence absence NN cord-292559-b21j9sf3 244 10 of of IN cord-292559-b21j9sf3 244 11 specific specific JJ cord-292559-b21j9sf3 244 12 hypotheses hypothesis NNS cord-292559-b21j9sf3 244 13 helps help VBZ cord-292559-b21j9sf3 244 14 to to TO cord-292559-b21j9sf3 244 15 avoid avoid VB cord-292559-b21j9sf3 244 16 problematic problematic JJ cord-292559-b21j9sf3 244 17 analytic analytic JJ cord-292559-b21j9sf3 244 18 approaches approach NNS cord-292559-b21j9sf3 244 19 resulting result VBG cord-292559-b21j9sf3 244 20 in in IN cord-292559-b21j9sf3 244 21 enhanced enhanced JJ cord-292559-b21j9sf3 244 22 false false JJ cord-292559-b21j9sf3 244 23 positives positive NNS cord-292559-b21j9sf3 244 24 [ [ -LRB- cord-292559-b21j9sf3 244 25 73 73 CD cord-292559-b21j9sf3 244 26 , , , cord-292559-b21j9sf3 244 27 74 74 CD cord-292559-b21j9sf3 244 28 ] ] -RRB- cord-292559-b21j9sf3 244 29 . . . cord-292559-b21j9sf3 245 1 Correcting correct VBG cord-292559-b21j9sf3 245 2 for for IN cord-292559-b21j9sf3 245 3 multiple multiple JJ cord-292559-b21j9sf3 245 4 comparisons comparison NNS cord-292559-b21j9sf3 245 5 is be VBZ cord-292559-b21j9sf3 245 6 also also RB cord-292559-b21j9sf3 245 7 critical critical JJ cord-292559-b21j9sf3 245 8 when when WRB cord-292559-b21j9sf3 245 9 conducting conduct VBG cord-292559-b21j9sf3 245 10 exploratory exploratory JJ cord-292559-b21j9sf3 245 11 analyses analysis NNS cord-292559-b21j9sf3 245 12 . . . cord-292559-b21j9sf3 246 1 It -PRON- PRP cord-292559-b21j9sf3 246 2 is be VBZ cord-292559-b21j9sf3 246 3 important important JJ cord-292559-b21j9sf3 246 4 to to TO cord-292559-b21j9sf3 246 5 account account VB cord-292559-b21j9sf3 246 6 for for IN cord-292559-b21j9sf3 246 7 experimentwide experimentwide JJ cord-292559-b21j9sf3 246 8 increased increase VBN cord-292559-b21j9sf3 246 9 false false JJ cord-292559-b21j9sf3 246 10 discovery discovery NN cord-292559-b21j9sf3 246 11 rates rate NNS cord-292559-b21j9sf3 246 12 , , , cord-292559-b21j9sf3 246 13 even even RB cord-292559-b21j9sf3 246 14 when when WRB cord-292559-b21j9sf3 246 15 conducting conduct VBG cord-292559-b21j9sf3 246 16 multilevel multilevel JJ cord-292559-b21j9sf3 246 17 modeling modeling NN cord-292559-b21j9sf3 246 18 . . . cord-292559-b21j9sf3 247 1 Further further RB cord-292559-b21j9sf3 247 2 , , , cord-292559-b21j9sf3 247 3 especially especially RB cord-292559-b21j9sf3 247 4 for for IN cord-292559-b21j9sf3 247 5 researchers researcher NNS cord-292559-b21j9sf3 247 6 conducting conduct VBG cord-292559-b21j9sf3 247 7 complicated complicated JJ cord-292559-b21j9sf3 247 8 interaction interaction NN cord-292559-b21j9sf3 247 9 or or CC cord-292559-b21j9sf3 247 10 genetic genetic JJ cord-292559-b21j9sf3 247 11 analyses analysis NNS cord-292559-b21j9sf3 247 12 , , , cord-292559-b21j9sf3 247 13 power power NN cord-292559-b21j9sf3 247 14 analyses analysis NNS cord-292559-b21j9sf3 247 15 should should MD cord-292559-b21j9sf3 247 16 be be VB cord-292559-b21j9sf3 247 17 conducted conduct VBN cord-292559-b21j9sf3 247 18 in in IN cord-292559-b21j9sf3 247 19 order order NN cord-292559-b21j9sf3 247 20 to to TO cord-292559-b21j9sf3 247 21 determine determine VB cord-292559-b21j9sf3 247 22 whether whether IN cord-292559-b21j9sf3 247 23 the the DT cord-292559-b21j9sf3 247 24 analysis analysis NN cord-292559-b21j9sf3 247 25 is be VBZ cord-292559-b21j9sf3 247 26 sufficiently sufficiently RB cord-292559-b21j9sf3 247 27 powered power VBN cord-292559-b21j9sf3 247 28 in in IN cord-292559-b21j9sf3 247 29 the the DT cord-292559-b21j9sf3 247 30 ABCD ABCD NNP cord-292559-b21j9sf3 247 31 Study Study NNP cord-292559-b21j9sf3 247 32 sample sample NN cord-292559-b21j9sf3 247 33 [ [ -LRB- cord-292559-b21j9sf3 247 34 75 75 CD cord-292559-b21j9sf3 247 35 ] ] -RRB- cord-292559-b21j9sf3 247 36 . . . cord-292559-b21j9sf3 248 1 Lastly lastly RB cord-292559-b21j9sf3 248 2 , , , cord-292559-b21j9sf3 248 3 researchers researcher NNS cord-292559-b21j9sf3 248 4 should should MD cord-292559-b21j9sf3 248 5 always always RB cord-292559-b21j9sf3 248 6 use use VB cord-292559-b21j9sf3 248 7 best good JJS cord-292559-b21j9sf3 248 8 practices practice NNS cord-292559-b21j9sf3 248 9 in in IN cord-292559-b21j9sf3 248 10 model model NN cord-292559-b21j9sf3 248 11 specification specification NN cord-292559-b21j9sf3 248 12 ( ( -LRB- cord-292559-b21j9sf3 248 13 e.g. e.g. RB cord-292559-b21j9sf3 248 14 , , , cord-292559-b21j9sf3 248 15 nesting nest VBG cord-292559-b21j9sf3 248 16 ABCD ABCD NNP cord-292559-b21j9sf3 248 17 Study Study NNP cord-292559-b21j9sf3 248 18 site site NN cord-292559-b21j9sf3 248 19 and and CC cord-292559-b21j9sf3 248 20 family family NN cord-292559-b21j9sf3 248 21 ) ) -RRB- cord-292559-b21j9sf3 248 22 [ [ -LRB- cord-292559-b21j9sf3 248 23 76 76 CD cord-292559-b21j9sf3 248 24 ] ] -RRB- cord-292559-b21j9sf3 248 25 . . . cord-292559-b21j9sf3 249 1 The the DT cord-292559-b21j9sf3 249 2 importance importance NN cord-292559-b21j9sf3 249 3 of of IN cord-292559-b21j9sf3 249 4 replication replication NN cord-292559-b21j9sf3 249 5 . . . cord-292559-b21j9sf3 250 1 The the DT cord-292559-b21j9sf3 250 2 importance importance NN cord-292559-b21j9sf3 250 3 of of IN cord-292559-b21j9sf3 250 4 replication replication NN cord-292559-b21j9sf3 250 5 is be VBZ cord-292559-b21j9sf3 250 6 increasingly increasingly RB cord-292559-b21j9sf3 250 7 highlighted highlight VBN cord-292559-b21j9sf3 250 8 as as IN cord-292559-b21j9sf3 250 9 a a DT cord-292559-b21j9sf3 250 10 part part NN cord-292559-b21j9sf3 250 11 of of IN cord-292559-b21j9sf3 250 12 robust robust JJ cord-292559-b21j9sf3 250 13 research research NN cord-292559-b21j9sf3 250 14 practices practice NNS cord-292559-b21j9sf3 250 15 [ [ -LRB- cord-292559-b21j9sf3 250 16 71 71 CD cord-292559-b21j9sf3 250 17 , , , cord-292559-b21j9sf3 250 18 77 77 CD cord-292559-b21j9sf3 250 19 ] ] -RRB- cord-292559-b21j9sf3 250 20 . . . cord-292559-b21j9sf3 251 1 Accordingly accordingly RB cord-292559-b21j9sf3 251 2 , , , cord-292559-b21j9sf3 251 3 another another DT cord-292559-b21j9sf3 251 4 opportunity opportunity NN cord-292559-b21j9sf3 251 5 that that WDT cord-292559-b21j9sf3 251 6 a a DT cord-292559-b21j9sf3 251 7 large large JJ cord-292559-b21j9sf3 251 8 study study NN cord-292559-b21j9sf3 251 9 such such JJ cord-292559-b21j9sf3 251 10 as as IN cord-292559-b21j9sf3 251 11 the the DT cord-292559-b21j9sf3 251 12 ABCD ABCD NNP cord-292559-b21j9sf3 251 13 Study Study NNP cord-292559-b21j9sf3 251 14 affords afford VBZ cord-292559-b21j9sf3 251 15 is be VBZ cord-292559-b21j9sf3 251 16 within within IN cord-292559-b21j9sf3 251 17 sample sample NN cord-292559-b21j9sf3 251 18 replication replication NN cord-292559-b21j9sf3 251 19 . . . cord-292559-b21j9sf3 252 1 The the DT cord-292559-b21j9sf3 252 2 opportunity opportunity NN cord-292559-b21j9sf3 252 3 to to TO cord-292559-b21j9sf3 252 4 conduct conduct VB cord-292559-b21j9sf3 252 5 a a DT cord-292559-b21j9sf3 252 6 within within IN cord-292559-b21j9sf3 252 7 sample sample NN cord-292559-b21j9sf3 252 8 replication replication NN cord-292559-b21j9sf3 252 9 can can MD cord-292559-b21j9sf3 252 10 come come VB cord-292559-b21j9sf3 252 11 in in IN cord-292559-b21j9sf3 252 12 several several JJ cord-292559-b21j9sf3 252 13 forms form NNS cord-292559-b21j9sf3 252 14 . . . cord-292559-b21j9sf3 253 1 One one CD cord-292559-b21j9sf3 253 2 possibility possibility NN cord-292559-b21j9sf3 253 3 is be VBZ cord-292559-b21j9sf3 253 4 researchers researcher NNS cord-292559-b21j9sf3 253 5 can can MD cord-292559-b21j9sf3 253 6 examine examine VB cord-292559-b21j9sf3 253 7 the the DT cord-292559-b21j9sf3 253 8 first first JJ cord-292559-b21j9sf3 253 9 data data NN cord-292559-b21j9sf3 253 10 release release NN cord-292559-b21j9sf3 253 11 ( ( -LRB- cord-292559-b21j9sf3 253 12 Data Data NNP cord-292559-b21j9sf3 253 13 Release release NN cord-292559-b21j9sf3 253 14 1.0.1 1.0.1 CD cord-292559-b21j9sf3 253 15 ; ; : cord-292559-b21j9sf3 253 16 N n CD cord-292559-b21j9sf3 253 17 = = SYM cord-292559-b21j9sf3 253 18 4524 4524 CD cord-292559-b21j9sf3 253 19 ) ) -RRB- cord-292559-b21j9sf3 253 20 and and CC cord-292559-b21j9sf3 253 21 then then RB cord-292559-b21j9sf3 253 22 replicate replicate VB cord-292559-b21j9sf3 253 23 findings finding NNS cord-292559-b21j9sf3 253 24 on on IN cord-292559-b21j9sf3 253 25 the the DT cord-292559-b21j9sf3 253 26 remainder remainder NN cord-292559-b21j9sf3 253 27 of of IN cord-292559-b21j9sf3 253 28 the the DT cord-292559-b21j9sf3 253 29 baseline baseline JJ cord-292559-b21j9sf3 253 30 sample sample NN cord-292559-b21j9sf3 253 31 ( ( -LRB- cord-292559-b21j9sf3 253 32 Data Data NNP cord-292559-b21j9sf3 253 33 Release Release NNP cord-292559-b21j9sf3 253 34 2.0 2.0 CD cord-292559-b21j9sf3 253 35 ; ; : cord-292559-b21j9sf3 253 36 remainder remainder VB cord-292559-b21j9sf3 253 37 sample sample NN cord-292559-b21j9sf3 253 38 N n CD cord-292559-b21j9sf3 253 39 = = SYM cord-292559-b21j9sf3 253 40 7351 7351 CD cord-292559-b21j9sf3 253 41 ) ) -RRB- cord-292559-b21j9sf3 253 42 . . . cord-292559-b21j9sf3 254 1 This this DT cord-292559-b21j9sf3 254 2 was be VBD cord-292559-b21j9sf3 254 3 recently recently RB cord-292559-b21j9sf3 254 4 done do VBN cord-292559-b21j9sf3 254 5 examining examine VBG cord-292559-b21j9sf3 254 6 associations association NNS cord-292559-b21j9sf3 254 7 with with IN cord-292559-b21j9sf3 254 8 PLEs ple NNS cord-292559-b21j9sf3 254 9 [ [ -LRB- cord-292559-b21j9sf3 254 10 41 41 CD cord-292559-b21j9sf3 254 11 ] ] -RRB- cord-292559-b21j9sf3 254 12 . . . cord-292559-b21j9sf3 255 1 In in IN cord-292559-b21j9sf3 255 2 subsequent subsequent JJ cord-292559-b21j9sf3 255 3 data data NN cord-292559-b21j9sf3 255 4 releases release NNS cord-292559-b21j9sf3 255 5 , , , cord-292559-b21j9sf3 255 6 researchers researcher NNS cord-292559-b21j9sf3 255 7 will will MD cord-292559-b21j9sf3 255 8 be be VB cord-292559-b21j9sf3 255 9 able able JJ cord-292559-b21j9sf3 255 10 to to TO cord-292559-b21j9sf3 255 11 replicate replicate VB cord-292559-b21j9sf3 255 12 results result NNS cord-292559-b21j9sf3 255 13 across across IN cord-292559-b21j9sf3 255 14 waves wave NNS cord-292559-b21j9sf3 255 15 , , , cord-292559-b21j9sf3 255 16 paying pay VBG cord-292559-b21j9sf3 255 17 close close JJ cord-292559-b21j9sf3 255 18 attention attention NN cord-292559-b21j9sf3 255 19 to to IN cord-292559-b21j9sf3 255 20 expected expect VBN cord-292559-b21j9sf3 255 21 developmental developmental JJ cord-292559-b21j9sf3 255 22 alterations alteration NNS cord-292559-b21j9sf3 255 23 that that WDT cord-292559-b21j9sf3 255 24 may may MD cord-292559-b21j9sf3 255 25 influence influence VB cord-292559-b21j9sf3 255 26 results result NNS cord-292559-b21j9sf3 255 27 . . . cord-292559-b21j9sf3 256 1 Second second RB cord-292559-b21j9sf3 256 2 , , , cord-292559-b21j9sf3 256 3 as as IN cord-292559-b21j9sf3 256 4 previously previously RB cord-292559-b21j9sf3 256 5 mentioned mention VBN cord-292559-b21j9sf3 256 6 in in IN cord-292559-b21j9sf3 256 7 the the DT cord-292559-b21j9sf3 256 8 exploratory exploratory JJ cord-292559-b21j9sf3 256 9 analyses analysis NNS cord-292559-b21j9sf3 256 10 paragraph paragraph NN cord-292559-b21j9sf3 256 11 , , , cord-292559-b21j9sf3 256 12 researchers researcher NNS cord-292559-b21j9sf3 256 13 can can MD cord-292559-b21j9sf3 256 14 divide divide VB cord-292559-b21j9sf3 256 15 the the DT cord-292559-b21j9sf3 256 16 sample sample NN cord-292559-b21j9sf3 256 17 into into IN cord-292559-b21j9sf3 256 18 discovery discovery NN cord-292559-b21j9sf3 256 19 and and CC cord-292559-b21j9sf3 256 20 replication replication NN cord-292559-b21j9sf3 256 21 datasets dataset NNS cord-292559-b21j9sf3 256 22 . . . cord-292559-b21j9sf3 257 1 Third third RB cord-292559-b21j9sf3 257 2 , , , cord-292559-b21j9sf3 257 3 researchers researcher NNS cord-292559-b21j9sf3 257 4 can can MD cord-292559-b21j9sf3 257 5 also also RB cord-292559-b21j9sf3 257 6 conduct conduct VB cord-292559-b21j9sf3 257 7 k k NN cord-292559-b21j9sf3 257 8 - - NN cord-292559-b21j9sf3 257 9 fold fold JJ cord-292559-b21j9sf3 257 10 ( ( -LRB- cord-292559-b21j9sf3 257 11 e.g. e.g. RB cord-292559-b21j9sf3 257 12 , , , cord-292559-b21j9sf3 257 13 10-fold 10-fold CD cord-292559-b21j9sf3 257 14 ) ) -RRB- cord-292559-b21j9sf3 257 15 cross cross NN cord-292559-b21j9sf3 257 16 - - NN cord-292559-b21j9sf3 257 17 replication replication JJ cord-292559-b21j9sf3 257 18 [ [ -LRB- cord-292559-b21j9sf3 257 19 78 78 CD cord-292559-b21j9sf3 257 20 ] ] -RRB- cord-292559-b21j9sf3 257 21 . . . cord-292559-b21j9sf3 258 1 K K NNP cord-292559-b21j9sf3 258 2 - - HYPH cord-292559-b21j9sf3 258 3 fold fold JJ cord-292559-b21j9sf3 258 4 cross cross NN cord-292559-b21j9sf3 258 5 validation validation NN cord-292559-b21j9sf3 258 6 is be VBZ cord-292559-b21j9sf3 258 7 used use VBN cord-292559-b21j9sf3 258 8 in in IN cord-292559-b21j9sf3 258 9 predictive predictive JJ cord-292559-b21j9sf3 258 10 modeling modeling NN cord-292559-b21j9sf3 258 11 to to TO cord-292559-b21j9sf3 258 12 test test VB cord-292559-b21j9sf3 258 13 a a DT cord-292559-b21j9sf3 258 14 model model NN cord-292559-b21j9sf3 258 15 's 's POS cord-292559-b21j9sf3 258 16 ability ability NN cord-292559-b21j9sf3 258 17 to to TO cord-292559-b21j9sf3 258 18 predict predict VB cord-292559-b21j9sf3 258 19 new new JJ cord-292559-b21j9sf3 258 20 data datum NNS cord-292559-b21j9sf3 258 21 not not RB cord-292559-b21j9sf3 258 22 used use VBN cord-292559-b21j9sf3 258 23 to to TO cord-292559-b21j9sf3 258 24 create create VB cord-292559-b21j9sf3 258 25 the the DT cord-292559-b21j9sf3 258 26 original original JJ cord-292559-b21j9sf3 258 27 model model NN cord-292559-b21j9sf3 258 28 . . . cord-292559-b21j9sf3 259 1 However however RB cord-292559-b21j9sf3 259 2 , , , cord-292559-b21j9sf3 259 3 the the DT cord-292559-b21j9sf3 259 4 gold gold NN cord-292559-b21j9sf3 259 5 standard standard NN cord-292559-b21j9sf3 259 6 in in IN cord-292559-b21j9sf3 259 7 replication replication NN cord-292559-b21j9sf3 259 8 is be VBZ cord-292559-b21j9sf3 259 9 to to TO cord-292559-b21j9sf3 259 10 use use VB cord-292559-b21j9sf3 259 11 an an DT cord-292559-b21j9sf3 259 12 independent independent JJ cord-292559-b21j9sf3 259 13 sample sample NN cord-292559-b21j9sf3 259 14 with with IN cord-292559-b21j9sf3 259 15 differing differ VBG cord-292559-b21j9sf3 259 16 methods method NNS cord-292559-b21j9sf3 259 17 and and CC cord-292559-b21j9sf3 259 18 sampling sampling NN cord-292559-b21j9sf3 259 19 techniques technique NNS cord-292559-b21j9sf3 259 20 in in IN cord-292559-b21j9sf3 259 21 order order NN cord-292559-b21j9sf3 259 22 to to TO cord-292559-b21j9sf3 259 23 ensure ensure VB cord-292559-b21j9sf3 259 24 that that IN cord-292559-b21j9sf3 259 25 effects effect NNS cord-292559-b21j9sf3 259 26 are be VBP cord-292559-b21j9sf3 259 27 replicable replicable JJ cord-292559-b21j9sf3 259 28 and and CC cord-292559-b21j9sf3 259 29 generalize generalize VB cord-292559-b21j9sf3 259 30 across across IN cord-292559-b21j9sf3 259 31 samples sample NNS cord-292559-b21j9sf3 259 32 . . . cord-292559-b21j9sf3 260 1 As as IN cord-292559-b21j9sf3 260 2 mentioned mention VBN cord-292559-b21j9sf3 260 3 in in IN cord-292559-b21j9sf3 260 4 the the DT cord-292559-b21j9sf3 260 5 " " `` cord-292559-b21j9sf3 260 6 Overview Overview NNP cord-292559-b21j9sf3 260 7 of of IN cord-292559-b21j9sf3 260 8 the the DT cord-292559-b21j9sf3 260 9 ABCD ABCD NNP cord-292559-b21j9sf3 260 10 Study Study NNP cord-292559-b21j9sf3 260 11 " " '' cord-292559-b21j9sf3 260 12 section section NN cord-292559-b21j9sf3 260 13 , , , cord-292559-b21j9sf3 260 14 there there EX cord-292559-b21j9sf3 260 15 are be VBP cord-292559-b21j9sf3 260 16 a a DT cord-292559-b21j9sf3 260 17 number number NN cord-292559-b21j9sf3 260 18 of of IN cord-292559-b21j9sf3 260 19 large large JJ cord-292559-b21j9sf3 260 20 - - HYPH cord-292559-b21j9sf3 260 21 scale scale NN cord-292559-b21j9sf3 260 22 studies study NNS cord-292559-b21j9sf3 260 23 that that WDT cord-292559-b21j9sf3 260 24 would would MD cord-292559-b21j9sf3 260 25 be be VB cord-292559-b21j9sf3 260 26 ideal ideal JJ cord-292559-b21j9sf3 260 27 for for IN cord-292559-b21j9sf3 260 28 such such PDT cord-292559-b21j9sf3 260 29 a a DT cord-292559-b21j9sf3 260 30 replication replication NN cord-292559-b21j9sf3 260 31 . . . cord-292559-b21j9sf3 261 1 For for IN cord-292559-b21j9sf3 261 2 example example NN cord-292559-b21j9sf3 261 3 , , , cord-292559-b21j9sf3 261 4 the the DT cord-292559-b21j9sf3 261 5 Generation Generation NNP cord-292559-b21j9sf3 261 6 R R NNP cord-292559-b21j9sf3 261 7 study study NN cord-292559-b21j9sf3 261 8 is be VBZ cord-292559-b21j9sf3 261 9 a a DT cord-292559-b21j9sf3 261 10 prospective prospective JJ cord-292559-b21j9sf3 261 11 longitudinal longitudinal JJ cord-292559-b21j9sf3 261 12 study study NN cord-292559-b21j9sf3 261 13 following follow VBG cord-292559-b21j9sf3 261 14 individuals individual NNS cord-292559-b21j9sf3 261 15 from from IN cord-292559-b21j9sf3 261 16 prenatally prenatally RB cord-292559-b21j9sf3 261 17 to to IN cord-292559-b21j9sf3 261 18 young young JJ cord-292559-b21j9sf3 261 19 adulthood adulthood NN cord-292559-b21j9sf3 262 1 ( ( -LRB- cord-292559-b21j9sf3 262 2 Table table NN cord-292559-b21j9sf3 262 3 2 2 CD cord-292559-b21j9sf3 262 4 ) ) -RRB- cord-292559-b21j9sf3 262 5 . . . cord-292559-b21j9sf3 263 1 As as IN cord-292559-b21j9sf3 263 2 with with IN cord-292559-b21j9sf3 263 3 the the DT cord-292559-b21j9sf3 263 4 ABCD ABCD NNP cord-292559-b21j9sf3 263 5 Study Study NNP cord-292559-b21j9sf3 263 6 , , , cord-292559-b21j9sf3 263 7 the the DT cord-292559-b21j9sf3 263 8 Generation Generation NNP cord-292559-b21j9sf3 263 9 R R NNP cord-292559-b21j9sf3 263 10 study study NN cord-292559-b21j9sf3 263 11 is be VBZ cord-292559-b21j9sf3 263 12 collecting collect VBG cord-292559-b21j9sf3 263 13 a a DT cord-292559-b21j9sf3 263 14 wide wide JJ cord-292559-b21j9sf3 263 15 range range NN cord-292559-b21j9sf3 263 16 of of IN cord-292559-b21j9sf3 263 17 outcomes outcome NNS cord-292559-b21j9sf3 263 18 , , , cord-292559-b21j9sf3 263 19 including include VBG cord-292559-b21j9sf3 263 20 physical physical JJ cord-292559-b21j9sf3 263 21 , , , cord-292559-b21j9sf3 263 22 behavioral behavioral JJ cord-292559-b21j9sf3 263 23 , , , cord-292559-b21j9sf3 263 24 cognitive cognitive JJ cord-292559-b21j9sf3 263 25 , , , cord-292559-b21j9sf3 263 26 biospecimens biospecimens NNP cord-292559-b21j9sf3 263 27 , , , cord-292559-b21j9sf3 263 28 and and CC cord-292559-b21j9sf3 263 29 MRI MRI NNP cord-292559-b21j9sf3 263 30 [ [ -LRB- cord-292559-b21j9sf3 263 31 5 5 CD cord-292559-b21j9sf3 263 32 ] ] -RRB- cord-292559-b21j9sf3 263 33 . . . cord-292559-b21j9sf3 264 1 In in IN cord-292559-b21j9sf3 264 2 addition addition NN cord-292559-b21j9sf3 264 3 , , , cord-292559-b21j9sf3 264 4 the the DT cord-292559-b21j9sf3 264 5 HCP HCP NNP cord-292559-b21j9sf3 264 6 - - HYPH cord-292559-b21j9sf3 264 7 D D NNP cord-292559-b21j9sf3 264 8 study study NN cord-292559-b21j9sf3 264 9 is be VBZ cord-292559-b21j9sf3 264 10 collecting collect VBG cord-292559-b21j9sf3 264 11 data datum NNS cord-292559-b21j9sf3 264 12 from from IN cord-292559-b21j9sf3 264 13 children child NNS cord-292559-b21j9sf3 264 14 ranging range VBG cord-292559-b21j9sf3 264 15 from from IN cord-292559-b21j9sf3 264 16 age age NN cord-292559-b21j9sf3 264 17 5 5 CD cord-292559-b21j9sf3 264 18 to to TO cord-292559-b21j9sf3 264 19 21 21 CD cord-292559-b21j9sf3 264 20 ( ( -LRB- cord-292559-b21j9sf3 264 21 Table table NN cord-292559-b21j9sf3 264 22 2 2 CD cord-292559-b21j9sf3 264 23 ) ) -RRB- cord-292559-b21j9sf3 264 24 [ [ -LRB- cord-292559-b21j9sf3 264 25 34 34 CD cord-292559-b21j9sf3 264 26 ] ] -RRB- cord-292559-b21j9sf3 264 27 . . . cord-292559-b21j9sf3 265 1 Although although IN cord-292559-b21j9sf3 265 2 the the DT cord-292559-b21j9sf3 265 3 focus focus NN cord-292559-b21j9sf3 265 4 of of IN cord-292559-b21j9sf3 265 5 the the DT cord-292559-b21j9sf3 265 6 HCP HCP NNP cord-292559-b21j9sf3 265 7 - - HYPH cord-292559-b21j9sf3 265 8 D D NNP cord-292559-b21j9sf3 265 9 study study NN cord-292559-b21j9sf3 265 10 is be VBZ cord-292559-b21j9sf3 265 11 on on IN cord-292559-b21j9sf3 265 12 the the DT cord-292559-b21j9sf3 265 13 development development NN cord-292559-b21j9sf3 265 14 of of IN cord-292559-b21j9sf3 265 15 the the DT cord-292559-b21j9sf3 265 16 brain brain NN cord-292559-b21j9sf3 265 17 , , , cord-292559-b21j9sf3 265 18 the the DT cord-292559-b21j9sf3 265 19 study study NN cord-292559-b21j9sf3 265 20 also also RB cord-292559-b21j9sf3 265 21 collects collect VBZ cord-292559-b21j9sf3 265 22 data datum NNS cord-292559-b21j9sf3 265 23 on on IN cord-292559-b21j9sf3 265 24 puberty puberty NN cord-292559-b21j9sf3 265 25 , , , cord-292559-b21j9sf3 265 26 physical physical JJ cord-292559-b21j9sf3 265 27 activity activity NN cord-292559-b21j9sf3 265 28 , , , cord-292559-b21j9sf3 265 29 health health NN cord-292559-b21j9sf3 265 30 , , , cord-292559-b21j9sf3 265 31 genetics genetics NN cord-292559-b21j9sf3 265 32 , , , cord-292559-b21j9sf3 265 33 and and CC cord-292559-b21j9sf3 265 34 other other JJ cord-292559-b21j9sf3 265 35 relevant relevant JJ cord-292559-b21j9sf3 265 36 mental mental JJ cord-292559-b21j9sf3 265 37 health health NN cord-292559-b21j9sf3 265 38 correlates correlate VBZ cord-292559-b21j9sf3 265 39 such such JJ cord-292559-b21j9sf3 265 40 as as IN cord-292559-b21j9sf3 265 41 stress stress NN cord-292559-b21j9sf3 265 42 [ [ -LRB- cord-292559-b21j9sf3 265 43 34 34 CD cord-292559-b21j9sf3 265 44 , , , cord-292559-b21j9sf3 265 45 79 79 CD cord-292559-b21j9sf3 265 46 ] ] -RRB- cord-292559-b21j9sf3 265 47 . . . cord-292559-b21j9sf3 266 1 Other other JJ cord-292559-b21j9sf3 266 2 studies study NNS cord-292559-b21j9sf3 266 3 that that WDT cord-292559-b21j9sf3 266 4 may may MD cord-292559-b21j9sf3 266 5 be be VB cord-292559-b21j9sf3 266 6 relevant relevant JJ cord-292559-b21j9sf3 266 7 for for IN cord-292559-b21j9sf3 266 8 replication replication NN cord-292559-b21j9sf3 266 9 efforts effort NNS cord-292559-b21j9sf3 266 10 can can MD cord-292559-b21j9sf3 266 11 be be VB cord-292559-b21j9sf3 266 12 found find VBN cord-292559-b21j9sf3 266 13 in in IN cord-292559-b21j9sf3 266 14 Table Table NNP cord-292559-b21j9sf3 266 15 2 2 CD cord-292559-b21j9sf3 266 16 . . . cord-292559-b21j9sf3 267 1 Developmental developmental JJ cord-292559-b21j9sf3 267 2 specificity specificity NN cord-292559-b21j9sf3 267 3 and and CC cord-292559-b21j9sf3 267 4 evolution evolution NN cord-292559-b21j9sf3 267 5 of of IN cord-292559-b21j9sf3 267 6 risk risk NN cord-292559-b21j9sf3 267 7 . . . cord-292559-b21j9sf3 268 1 The the DT cord-292559-b21j9sf3 268 2 ABCD ABCD NNP cord-292559-b21j9sf3 268 3 Study Study NNP cord-292559-b21j9sf3 268 4 will will MD cord-292559-b21j9sf3 268 5 provide provide VB cord-292559-b21j9sf3 268 6 one one CD cord-292559-b21j9sf3 268 7 of of IN cord-292559-b21j9sf3 268 8 the the DT cord-292559-b21j9sf3 268 9 first first JJ cord-292559-b21j9sf3 268 10 opportunities opportunity NNS cord-292559-b21j9sf3 268 11 to to TO cord-292559-b21j9sf3 268 12 examine examine VB cord-292559-b21j9sf3 268 13 a a DT cord-292559-b21j9sf3 268 14 wealth wealth NN cord-292559-b21j9sf3 268 15 of of IN cord-292559-b21j9sf3 268 16 neuroimaging neuroimaging NN cord-292559-b21j9sf3 268 17 , , , cord-292559-b21j9sf3 268 18 genetics genetics NN cord-292559-b21j9sf3 268 19 , , , cord-292559-b21j9sf3 268 20 cognition cognition NN cord-292559-b21j9sf3 268 21 , , , cord-292559-b21j9sf3 268 22 psychopathological psychopathological JJ cord-292559-b21j9sf3 268 23 , , , cord-292559-b21j9sf3 268 24 and and CC cord-292559-b21j9sf3 268 25 psychosocial psychosocial JJ cord-292559-b21j9sf3 268 26 factors factor NNS cord-292559-b21j9sf3 268 27 in in IN cord-292559-b21j9sf3 268 28 the the DT cord-292559-b21j9sf3 268 29 same same JJ cord-292559-b21j9sf3 268 30 youth youth NN cord-292559-b21j9sf3 268 31 in in IN cord-292559-b21j9sf3 268 32 middle middle JJ cord-292559-b21j9sf3 268 33 childhood childhood NN cord-292559-b21j9sf3 268 34 , , , cord-292559-b21j9sf3 268 35 adolescence adolescence NN cord-292559-b21j9sf3 268 36 , , , cord-292559-b21j9sf3 268 37 and and CC cord-292559-b21j9sf3 268 38 early early JJ cord-292559-b21j9sf3 268 39 adulthood adulthood NN cord-292559-b21j9sf3 268 40 . . . cord-292559-b21j9sf3 269 1 It -PRON- PRP cord-292559-b21j9sf3 269 2 will will MD cord-292559-b21j9sf3 269 3 be be VB cord-292559-b21j9sf3 269 4 important important JJ cord-292559-b21j9sf3 269 5 for for IN cord-292559-b21j9sf3 269 6 researchers researcher NNS cord-292559-b21j9sf3 269 7 to to TO cord-292559-b21j9sf3 269 8 consider consider VB cord-292559-b21j9sf3 269 9 the the DT cord-292559-b21j9sf3 269 10 developmental developmental JJ cord-292559-b21j9sf3 269 11 period period NN cord-292559-b21j9sf3 269 12 in in IN cord-292559-b21j9sf3 269 13 question question NN cord-292559-b21j9sf3 269 14 in in IN cord-292559-b21j9sf3 269 15 order order NN cord-292559-b21j9sf3 269 16 to to TO cord-292559-b21j9sf3 269 17 properly properly RB cord-292559-b21j9sf3 269 18 formulate formulate VB cord-292559-b21j9sf3 269 19 hypotheses hypothesis NNS cord-292559-b21j9sf3 269 20 regarding regard VBG cord-292559-b21j9sf3 269 21 risk risk NN cord-292559-b21j9sf3 269 22 in in IN cord-292559-b21j9sf3 269 23 each each DT cord-292559-b21j9sf3 269 24 age age NN cord-292559-b21j9sf3 269 25 group group NN cord-292559-b21j9sf3 269 26 , , , cord-292559-b21j9sf3 269 27 as as IN cord-292559-b21j9sf3 269 28 each each DT cord-292559-b21j9sf3 269 29 period period NN cord-292559-b21j9sf3 269 30 is be VBZ cord-292559-b21j9sf3 269 31 defined define VBN cord-292559-b21j9sf3 269 32 by by IN cord-292559-b21j9sf3 269 33 a a DT cord-292559-b21j9sf3 269 34 unique unique JJ cord-292559-b21j9sf3 269 35 set set NN cord-292559-b21j9sf3 269 36 of of IN cord-292559-b21j9sf3 269 37 psychosocial psychosocial JJ cord-292559-b21j9sf3 269 38 and and CC cord-292559-b21j9sf3 269 39 neurobiological neurobiological JJ cord-292559-b21j9sf3 269 40 alterations alteration NNS cord-292559-b21j9sf3 269 41 . . . cord-292559-b21j9sf3 270 1 For for IN cord-292559-b21j9sf3 270 2 example example NN cord-292559-b21j9sf3 270 3 , , , cord-292559-b21j9sf3 270 4 middle middle JJ cord-292559-b21j9sf3 270 5 childhood childhood NN cord-292559-b21j9sf3 270 6 is be VBZ cord-292559-b21j9sf3 270 7 associated associate VBN cord-292559-b21j9sf3 270 8 with with IN cord-292559-b21j9sf3 270 9 several several JJ cord-292559-b21j9sf3 270 10 changes change NNS cord-292559-b21j9sf3 270 11 , , , cord-292559-b21j9sf3 270 12 including include VBG cord-292559-b21j9sf3 270 13 continued continue VBN cord-292559-b21j9sf3 270 14 neuromaturational neuromaturational JJ cord-292559-b21j9sf3 270 15 processes process NNS cord-292559-b21j9sf3 270 16 that that WDT cord-292559-b21j9sf3 270 17 began begin VBD cord-292559-b21j9sf3 270 18 in in IN cord-292559-b21j9sf3 270 19 childhood childhood NN cord-292559-b21j9sf3 270 20 , , , cord-292559-b21j9sf3 270 21 such such JJ cord-292559-b21j9sf3 270 22 as as IN cord-292559-b21j9sf3 270 23 increases increase NNS cord-292559-b21j9sf3 270 24 in in IN cord-292559-b21j9sf3 270 25 both both DT cord-292559-b21j9sf3 270 26 gray gray JJ cord-292559-b21j9sf3 270 27 and and CC cord-292559-b21j9sf3 270 28 white white JJ cord-292559-b21j9sf3 270 29 matter matter NN cord-292559-b21j9sf3 270 30 [ [ -LRB- cord-292559-b21j9sf3 270 31 80 80 CD cord-292559-b21j9sf3 270 32 ] ] -RRB- cord-292559-b21j9sf3 270 33 . . . cord-292559-b21j9sf3 271 1 Adolescence adolescence NN cord-292559-b21j9sf3 271 2 is be VBZ cord-292559-b21j9sf3 271 3 a a DT cord-292559-b21j9sf3 271 4 period period NN cord-292559-b21j9sf3 271 5 of of IN cord-292559-b21j9sf3 271 6 often often RB cord-292559-b21j9sf3 271 7 dramatic dramatic JJ cord-292559-b21j9sf3 271 8 changes change NNS cord-292559-b21j9sf3 271 9 , , , cord-292559-b21j9sf3 271 10 including include VBG cord-292559-b21j9sf3 271 11 hormonal hormonal JJ cord-292559-b21j9sf3 271 12 fluctuations fluctuation NNS cord-292559-b21j9sf3 271 13 and and CC cord-292559-b21j9sf3 271 14 substantial substantial JJ cord-292559-b21j9sf3 271 15 pruning pruning NN cord-292559-b21j9sf3 271 16 processes process NNS cord-292559-b21j9sf3 271 17 [ [ -LRB- cord-292559-b21j9sf3 271 18 80 80 CD cord-292559-b21j9sf3 271 19 ] ] -RRB- cord-292559-b21j9sf3 271 20 [ [ -LRB- cord-292559-b21j9sf3 271 21 81 81 CD cord-292559-b21j9sf3 271 22 ] ] -RRB- cord-292559-b21j9sf3 271 23 [ [ -LRB- cord-292559-b21j9sf3 271 24 82 82 CD cord-292559-b21j9sf3 271 25 ] ] -RRB- cord-292559-b21j9sf3 271 26 [ [ -LRB- cord-292559-b21j9sf3 271 27 83 83 CD cord-292559-b21j9sf3 271 28 ] ] -RRB- cord-292559-b21j9sf3 271 29 . . . cord-292559-b21j9sf3 272 1 Lastly lastly RB cord-292559-b21j9sf3 272 2 , , , cord-292559-b21j9sf3 272 3 young young JJ cord-292559-b21j9sf3 272 4 adulthood adulthood NN cord-292559-b21j9sf3 272 5 is be VBZ cord-292559-b21j9sf3 272 6 associated associate VBN cord-292559-b21j9sf3 272 7 with with IN cord-292559-b21j9sf3 272 8 another another DT cord-292559-b21j9sf3 272 9 set set NN cord-292559-b21j9sf3 272 10 of of IN cord-292559-b21j9sf3 272 11 changes change NNS cord-292559-b21j9sf3 272 12 , , , cord-292559-b21j9sf3 272 13 including include VBG cord-292559-b21j9sf3 272 14 in in IN cord-292559-b21j9sf3 272 15 role role NN cord-292559-b21j9sf3 272 16 functioning function VBG cord-292559-b21j9sf3 272 17 [ [ -LRB- cord-292559-b21j9sf3 272 18 84 84 CD cord-292559-b21j9sf3 272 19 ] ] -RRB- cord-292559-b21j9sf3 272 20 . . . cord-292559-b21j9sf3 273 1 In in IN cord-292559-b21j9sf3 273 2 terms term NNS cord-292559-b21j9sf3 273 3 of of IN cord-292559-b21j9sf3 273 4 the the DT cord-292559-b21j9sf3 273 5 development development NN cord-292559-b21j9sf3 273 6 of of IN cord-292559-b21j9sf3 273 7 risk risk NN cord-292559-b21j9sf3 273 8 , , , cord-292559-b21j9sf3 273 9 each each DT cord-292559-b21j9sf3 273 10 stage stage NN cord-292559-b21j9sf3 273 11 has have VBZ cord-292559-b21j9sf3 273 12 its -PRON- PRP$ cord-292559-b21j9sf3 273 13 own own JJ cord-292559-b21j9sf3 273 14 unique unique JJ cord-292559-b21j9sf3 273 15 set set NN cord-292559-b21j9sf3 273 16 of of IN cord-292559-b21j9sf3 273 17 risk risk NN cord-292559-b21j9sf3 273 18 - - HYPH cord-292559-b21j9sf3 273 19 related relate VBN cord-292559-b21j9sf3 273 20 factors factor NNS cord-292559-b21j9sf3 273 21 and and CC cord-292559-b21j9sf3 273 22 developmental developmental JJ cord-292559-b21j9sf3 273 23 changes change NNS cord-292559-b21j9sf3 273 24 . . . cord-292559-b21j9sf3 274 1 For for IN cord-292559-b21j9sf3 274 2 example example NN cord-292559-b21j9sf3 274 3 , , , cord-292559-b21j9sf3 274 4 adolescence adolescence NN cord-292559-b21j9sf3 274 5 is be VBZ cord-292559-b21j9sf3 274 6 associated associate VBN cord-292559-b21j9sf3 274 7 with with IN cord-292559-b21j9sf3 274 8 a a DT cord-292559-b21j9sf3 274 9 spiked spiked JJ cord-292559-b21j9sf3 274 10 increase increase NN cord-292559-b21j9sf3 274 11 in in IN cord-292559-b21j9sf3 274 12 risk risk NN cord-292559-b21j9sf3 274 13 - - HYPH cord-292559-b21j9sf3 274 14 taking take VBG cord-292559-b21j9sf3 274 15 behaviors behavior NNS cord-292559-b21j9sf3 274 16 , , , cord-292559-b21j9sf3 274 17 including include VBG cord-292559-b21j9sf3 274 18 substance substance NN cord-292559-b21j9sf3 274 19 use use NN cord-292559-b21j9sf3 274 20 [ [ -LRB- cord-292559-b21j9sf3 274 21 8 8 CD cord-292559-b21j9sf3 274 22 , , , cord-292559-b21j9sf3 274 23 13 13 CD cord-292559-b21j9sf3 274 24 ] ] -RRB- cord-292559-b21j9sf3 274 25 . . . cord-292559-b21j9sf3 275 1 Researchers researcher NNS cord-292559-b21j9sf3 275 2 interested interested JJ cord-292559-b21j9sf3 275 3 in in IN cord-292559-b21j9sf3 275 4 examining examine VBG cord-292559-b21j9sf3 275 5 ABCD ABCD NNP cord-292559-b21j9sf3 275 6 Study Study NNP cord-292559-b21j9sf3 275 7 data datum NNS cord-292559-b21j9sf3 275 8 should should MD cord-292559-b21j9sf3 275 9 carefully carefully RB cord-292559-b21j9sf3 275 10 tune tune VB cord-292559-b21j9sf3 275 11 their -PRON- PRP$ cord-292559-b21j9sf3 275 12 questions question NNS cord-292559-b21j9sf3 275 13 depending depend VBG cord-292559-b21j9sf3 275 14 on on IN cord-292559-b21j9sf3 275 15 the the DT cord-292559-b21j9sf3 275 16 developmental developmental JJ cord-292559-b21j9sf3 275 17 period period NN cord-292559-b21j9sf3 275 18 from from IN cord-292559-b21j9sf3 275 19 which which WDT cord-292559-b21j9sf3 275 20 they -PRON- PRP cord-292559-b21j9sf3 275 21 are be VBP cord-292559-b21j9sf3 275 22 drawing draw VBG cord-292559-b21j9sf3 275 23 their -PRON- PRP$ cord-292559-b21j9sf3 275 24 sample sample NN cord-292559-b21j9sf3 275 25 . . . cord-292559-b21j9sf3 276 1 For for IN cord-292559-b21j9sf3 276 2 example example NN cord-292559-b21j9sf3 276 3 , , , cord-292559-b21j9sf3 276 4 researchers researcher NNS cord-292559-b21j9sf3 276 5 interested interested JJ cord-292559-b21j9sf3 276 6 in in IN cord-292559-b21j9sf3 276 7 understanding understand VBG cord-292559-b21j9sf3 276 8 the the DT cord-292559-b21j9sf3 276 9 progression progression NN cord-292559-b21j9sf3 276 10 of of IN cord-292559-b21j9sf3 276 11 risktaking risktake VBG cord-292559-b21j9sf3 276 12 behaviors behavior NNS cord-292559-b21j9sf3 276 13 , , , cord-292559-b21j9sf3 276 14 such such JJ cord-292559-b21j9sf3 276 15 as as IN cord-292559-b21j9sf3 276 16 the the DT cord-292559-b21j9sf3 276 17 initiation initiation NN cord-292559-b21j9sf3 276 18 of of IN cord-292559-b21j9sf3 276 19 cannabis cannabis NN cord-292559-b21j9sf3 276 20 use use NN cord-292559-b21j9sf3 276 21 , , , cord-292559-b21j9sf3 276 22 would would MD cord-292559-b21j9sf3 276 23 likely likely RB cord-292559-b21j9sf3 276 24 examine examine VB cord-292559-b21j9sf3 276 25 future future JJ cord-292559-b21j9sf3 276 26 waves wave NNS cord-292559-b21j9sf3 276 27 of of IN cord-292559-b21j9sf3 276 28 the the DT cord-292559-b21j9sf3 276 29 ABCD ABCD NNP cord-292559-b21j9sf3 276 30 Study Study NNP cord-292559-b21j9sf3 276 31 ( ( -LRB- cord-292559-b21j9sf3 276 32 e.g. e.g. RB cord-292559-b21j9sf3 276 33 , , , cord-292559-b21j9sf3 276 34 at at IN cord-292559-b21j9sf3 276 35 year year NN cord-292559-b21j9sf3 276 36 4 4 CD cord-292559-b21j9sf3 276 37 youth youth NN cord-292559-b21j9sf3 276 38 = = SYM cord-292559-b21j9sf3 276 39 13 13 CD cord-292559-b21j9sf3 276 40 - - HYPH cord-292559-b21j9sf3 276 41 14-years 14-years CD cord-292559-b21j9sf3 276 42 - - HYPH cord-292559-b21j9sf3 276 43 old old JJ cord-292559-b21j9sf3 276 44 ) ) -RRB- cord-292559-b21j9sf3 276 45 to to TO cord-292559-b21j9sf3 276 46 identify identify VB cord-292559-b21j9sf3 276 47 outcome outcome NN cord-292559-b21j9sf3 276 48 measures measure NNS cord-292559-b21j9sf3 276 49 and and CC cord-292559-b21j9sf3 276 50 to to TO cord-292559-b21j9sf3 276 51 evaluate evaluate VB cord-292559-b21j9sf3 276 52 response response NN cord-292559-b21j9sf3 276 53 to to IN cord-292559-b21j9sf3 276 54 substance substance NN cord-292559-b21j9sf3 276 55 use use NN cord-292559-b21j9sf3 276 56 , , , cord-292559-b21j9sf3 276 57 but but CC cord-292559-b21j9sf3 276 58 maybe maybe RB cord-292559-b21j9sf3 276 59 using use VBG cord-292559-b21j9sf3 276 60 predictors predictor NNS cord-292559-b21j9sf3 276 61 from from IN cord-292559-b21j9sf3 276 62 an an DT cord-292559-b21j9sf3 276 63 earlier early JJR cord-292559-b21j9sf3 276 64 developmental developmental JJ cord-292559-b21j9sf3 276 65 stage stage NN cord-292559-b21j9sf3 276 66 . . . cord-292559-b21j9sf3 277 1 The the DT cord-292559-b21j9sf3 277 2 developmental developmental JJ cord-292559-b21j9sf3 277 3 period period NN cord-292559-b21j9sf3 277 4 in in IN cord-292559-b21j9sf3 277 5 question question NN cord-292559-b21j9sf3 277 6 will will MD cord-292559-b21j9sf3 277 7 also also RB cord-292559-b21j9sf3 277 8 be be VB cord-292559-b21j9sf3 277 9 critical critical JJ cord-292559-b21j9sf3 277 10 in in IN cord-292559-b21j9sf3 277 11 terms term NNS cord-292559-b21j9sf3 277 12 of of IN cord-292559-b21j9sf3 277 13 the the DT cord-292559-b21j9sf3 277 14 covariates covariate NNS cord-292559-b21j9sf3 277 15 of of IN cord-292559-b21j9sf3 277 16 interest interest NN cord-292559-b21j9sf3 277 17 in in IN cord-292559-b21j9sf3 277 18 analyses analysis NNS cord-292559-b21j9sf3 277 19 . . . cord-292559-b21j9sf3 278 1 Pubertal pubertal JJ cord-292559-b21j9sf3 278 2 status status NN cord-292559-b21j9sf3 278 3 will will MD cord-292559-b21j9sf3 278 4 be be VB cord-292559-b21j9sf3 278 5 an an DT cord-292559-b21j9sf3 278 6 important important JJ cord-292559-b21j9sf3 278 7 covariate covariate NN cord-292559-b21j9sf3 278 8 in in IN cord-292559-b21j9sf3 278 9 later later JJ cord-292559-b21j9sf3 278 10 middle middle JJ cord-292559-b21j9sf3 278 11 childhood childhood NN cord-292559-b21j9sf3 278 12 / / SYM cord-292559-b21j9sf3 278 13 early early JJ cord-292559-b21j9sf3 278 14 adolescence adolescence NN cord-292559-b21j9sf3 278 15 . . . cord-292559-b21j9sf3 279 1 Likewise likewise RB cord-292559-b21j9sf3 279 2 , , , cord-292559-b21j9sf3 279 3 substance substance NN cord-292559-b21j9sf3 279 4 use use NN cord-292559-b21j9sf3 279 5 will will MD cord-292559-b21j9sf3 279 6 be be VB cord-292559-b21j9sf3 279 7 an an DT cord-292559-b21j9sf3 279 8 important important JJ cord-292559-b21j9sf3 279 9 covariate covariate NN cord-292559-b21j9sf3 279 10 for for IN cord-292559-b21j9sf3 279 11 many many JJ cord-292559-b21j9sf3 279 12 analyses analysis NNS cord-292559-b21j9sf3 279 13 in in IN cord-292559-b21j9sf3 279 14 later later RB cord-292559-b21j9sf3 279 15 adolescence/ adolescence/ CD cord-292559-b21j9sf3 279 16 early early JJ cord-292559-b21j9sf3 279 17 adulthood adulthood NN cord-292559-b21j9sf3 279 18 . . . cord-292559-b21j9sf3 280 1 The the DT cord-292559-b21j9sf3 280 2 ABCD ABCD NNP cord-292559-b21j9sf3 280 3 Study Study NNP cord-292559-b21j9sf3 280 4 also also RB cord-292559-b21j9sf3 280 5 will will MD cord-292559-b21j9sf3 280 6 provide provide VB cord-292559-b21j9sf3 280 7 the the DT cord-292559-b21j9sf3 280 8 opportunity opportunity NN cord-292559-b21j9sf3 280 9 to to TO cord-292559-b21j9sf3 280 10 examine examine VB cord-292559-b21j9sf3 280 11 the the DT cord-292559-b21j9sf3 280 12 evolution evolution NN cord-292559-b21j9sf3 280 13 of of IN cord-292559-b21j9sf3 280 14 risk risk NN cord-292559-b21j9sf3 280 15 , , , cord-292559-b21j9sf3 280 16 including include VBG cord-292559-b21j9sf3 280 17 how how WRB cord-292559-b21j9sf3 280 18 risk risk NN cord-292559-b21j9sf3 280 19 factors factor NNS cord-292559-b21j9sf3 280 20 change change VBP cord-292559-b21j9sf3 280 21 across across IN cord-292559-b21j9sf3 280 22 development development NN cord-292559-b21j9sf3 280 23 and and CC cord-292559-b21j9sf3 280 24 to to TO cord-292559-b21j9sf3 280 25 determine determine VB cord-292559-b21j9sf3 280 26 whether whether IN cord-292559-b21j9sf3 280 27 there there EX cord-292559-b21j9sf3 280 28 are be VBP cord-292559-b21j9sf3 280 29 important important JJ cord-292559-b21j9sf3 280 30 variations variation NNS cord-292559-b21j9sf3 280 31 in in IN cord-292559-b21j9sf3 280 32 the the DT cord-292559-b21j9sf3 280 33 most most RBS cord-292559-b21j9sf3 280 34 relevant relevant JJ cord-292559-b21j9sf3 280 35 risk risk NN cord-292559-b21j9sf3 280 36 factors factor NNS cord-292559-b21j9sf3 280 37 at at IN cord-292559-b21j9sf3 280 38 different different JJ cord-292559-b21j9sf3 280 39 phases phase NNS cord-292559-b21j9sf3 280 40 of of IN cord-292559-b21j9sf3 280 41 development development NN cord-292559-b21j9sf3 280 42 . . . cord-292559-b21j9sf3 281 1 In in IN cord-292559-b21j9sf3 281 2 terms term NNS cord-292559-b21j9sf3 281 3 of of IN cord-292559-b21j9sf3 281 4 defining define VBG cord-292559-b21j9sf3 281 5 factors factor NNS cord-292559-b21j9sf3 281 6 that that WDT cord-292559-b21j9sf3 281 7 predict predict VBP cord-292559-b21j9sf3 281 8 variation variation NN cord-292559-b21j9sf3 281 9 in in IN cord-292559-b21j9sf3 281 10 developmental developmental JJ cord-292559-b21j9sf3 281 11 trajectories trajectory NNS cord-292559-b21j9sf3 281 12 , , , cord-292559-b21j9sf3 281 13 life life NN cord-292559-b21j9sf3 281 14 course course NN cord-292559-b21j9sf3 281 15 [ [ -LRB- cord-292559-b21j9sf3 281 16 85 85 CD cord-292559-b21j9sf3 281 17 ] ] -RRB- cord-292559-b21j9sf3 281 18 and and CC cord-292559-b21j9sf3 281 19 developmental developmental JJ cord-292559-b21j9sf3 281 20 psychopathology psychopathology NN cord-292559-b21j9sf3 281 21 [ [ -LRB- cord-292559-b21j9sf3 281 22 86 86 CD cord-292559-b21j9sf3 281 23 ] ] -RRB- cord-292559-b21j9sf3 281 24 theories theory NNS cord-292559-b21j9sf3 281 25 suggest suggest VBP cord-292559-b21j9sf3 281 26 that that IN cord-292559-b21j9sf3 281 27 early early JJ cord-292559-b21j9sf3 281 28 negative negative JJ cord-292559-b21j9sf3 281 29 experiences experience NNS cord-292559-b21j9sf3 281 30 can can MD cord-292559-b21j9sf3 281 31 alter alter VB cord-292559-b21j9sf3 281 32 a a DT cord-292559-b21j9sf3 281 33 youth youth NN cord-292559-b21j9sf3 281 34 's 's POS cord-292559-b21j9sf3 281 35 developmental developmental JJ cord-292559-b21j9sf3 281 36 trajectory trajectory NN cord-292559-b21j9sf3 281 37 [ [ -LRB- cord-292559-b21j9sf3 281 38 87 87 CD cord-292559-b21j9sf3 281 39 , , , cord-292559-b21j9sf3 281 40 88 88 CD cord-292559-b21j9sf3 281 41 ] ] -RRB- cord-292559-b21j9sf3 281 42 and and CC cord-292559-b21j9sf3 281 43 the the DT cord-292559-b21j9sf3 281 44 accomplishment accomplishment NN cord-292559-b21j9sf3 281 45 of of IN cord-292559-b21j9sf3 281 46 developmental developmental JJ cord-292559-b21j9sf3 281 47 milestones milestone NNS cord-292559-b21j9sf3 281 48 . . . cord-292559-b21j9sf3 282 1 However however RB cord-292559-b21j9sf3 282 2 , , , cord-292559-b21j9sf3 282 3 research research NN cord-292559-b21j9sf3 282 4 has have VBZ cord-292559-b21j9sf3 282 5 not not RB cord-292559-b21j9sf3 282 6 elucidated elucidate VBN cord-292559-b21j9sf3 282 7 whether whether IN cord-292559-b21j9sf3 282 8 the the DT cord-292559-b21j9sf3 282 9 consequences consequence NNS cord-292559-b21j9sf3 282 10 of of IN cord-292559-b21j9sf3 282 11 negative negative JJ cord-292559-b21j9sf3 282 12 life life NN cord-292559-b21j9sf3 282 13 events event NNS cord-292559-b21j9sf3 282 14 in in IN cord-292559-b21j9sf3 282 15 terms term NNS cord-292559-b21j9sf3 282 16 of of IN cord-292559-b21j9sf3 282 17 mental mental JJ cord-292559-b21j9sf3 282 18 health health NN cord-292559-b21j9sf3 282 19 are be VBP cord-292559-b21j9sf3 282 20 stronger strong JJR cord-292559-b21j9sf3 282 21 during during IN cord-292559-b21j9sf3 282 22 different different JJ cord-292559-b21j9sf3 282 23 development development NN cord-292559-b21j9sf3 282 24 periods period NNS cord-292559-b21j9sf3 282 25 , , , cord-292559-b21j9sf3 282 26 such such JJ cord-292559-b21j9sf3 282 27 as as IN cord-292559-b21j9sf3 282 28 in in IN cord-292559-b21j9sf3 282 29 middle middle JJ cord-292559-b21j9sf3 282 30 childhood childhood NN cord-292559-b21j9sf3 282 31 versus versus IN cord-292559-b21j9sf3 282 32 adulthood adulthood NN cord-292559-b21j9sf3 282 33 . . . cord-292559-b21j9sf3 283 1 This this DT cord-292559-b21j9sf3 283 2 would would MD cord-292559-b21j9sf3 283 3 have have VB cord-292559-b21j9sf3 283 4 critical critical JJ cord-292559-b21j9sf3 283 5 treatment treatment NN cord-292559-b21j9sf3 283 6 and and CC cord-292559-b21j9sf3 283 7 policy policy NN cord-292559-b21j9sf3 283 8 implications implication NNS cord-292559-b21j9sf3 283 9 . . . cord-292559-b21j9sf3 284 1 It -PRON- PRP cord-292559-b21j9sf3 284 2 is be VBZ cord-292559-b21j9sf3 284 3 also also RB cord-292559-b21j9sf3 284 4 possible possible JJ cord-292559-b21j9sf3 284 5 that that IN cord-292559-b21j9sf3 284 6 the the DT cord-292559-b21j9sf3 284 7 factors factor NNS cord-292559-b21j9sf3 284 8 associated associate VBN cord-292559-b21j9sf3 284 9 with with IN cord-292559-b21j9sf3 284 10 risk risk NN cord-292559-b21j9sf3 284 11 may may MD cord-292559-b21j9sf3 284 12 be be VB cord-292559-b21j9sf3 284 13 qualitatively qualitatively RB cord-292559-b21j9sf3 284 14 different different JJ cord-292559-b21j9sf3 284 15 during during IN cord-292559-b21j9sf3 284 16 different different JJ cord-292559-b21j9sf3 284 17 developmental developmental JJ cord-292559-b21j9sf3 284 18 periods period NNS cord-292559-b21j9sf3 284 19 . . . cord-292559-b21j9sf3 285 1 For for IN cord-292559-b21j9sf3 285 2 example example NN cord-292559-b21j9sf3 285 3 , , , cord-292559-b21j9sf3 285 4 factors factor NNS cord-292559-b21j9sf3 285 5 associated associate VBN cord-292559-b21j9sf3 285 6 with with IN cord-292559-b21j9sf3 285 7 risk risk NN cord-292559-b21j9sf3 285 8 for for IN cord-292559-b21j9sf3 285 9 depressive depressive JJ cord-292559-b21j9sf3 285 10 symptoms symptom NNS cord-292559-b21j9sf3 285 11 in in IN cord-292559-b21j9sf3 285 12 middle middle JJ cord-292559-b21j9sf3 285 13 childhood childhood NN cord-292559-b21j9sf3 285 14 , , , cord-292559-b21j9sf3 285 15 such such JJ cord-292559-b21j9sf3 285 16 as as IN cord-292559-b21j9sf3 285 17 lower low JJR cord-292559-b21j9sf3 285 18 physical physical JJ cord-292559-b21j9sf3 285 19 activity activity NN cord-292559-b21j9sf3 285 20 [ [ -LRB- cord-292559-b21j9sf3 285 21 89 89 CD cord-292559-b21j9sf3 285 22 ] ] -RRB- cord-292559-b21j9sf3 285 23 , , , cord-292559-b21j9sf3 285 24 may may MD cord-292559-b21j9sf3 285 25 not not RB cord-292559-b21j9sf3 285 26 be be VB cord-292559-b21j9sf3 285 27 associated associate VBN cord-292559-b21j9sf3 285 28 with with IN cord-292559-b21j9sf3 285 29 risk risk NN cord-292559-b21j9sf3 285 30 for for IN cord-292559-b21j9sf3 285 31 depressive depressive JJ cord-292559-b21j9sf3 285 32 symptoms symptom NNS cord-292559-b21j9sf3 285 33 in in IN cord-292559-b21j9sf3 285 34 young young JJ cord-292559-b21j9sf3 285 35 adulthood adulthood NN cord-292559-b21j9sf3 285 36 , , , cord-292559-b21j9sf3 285 37 as as IN cord-292559-b21j9sf3 285 38 these these DT cord-292559-b21j9sf3 285 39 factors factor NNS cord-292559-b21j9sf3 285 40 become become VBP cord-292559-b21j9sf3 285 41 more more RBR cord-292559-b21j9sf3 285 42 normative normative JJ cord-292559-b21j9sf3 285 43 . . . cord-292559-b21j9sf3 286 1 In in IN cord-292559-b21j9sf3 286 2 contrast contrast NN cord-292559-b21j9sf3 286 3 , , , cord-292559-b21j9sf3 286 4 other other JJ cord-292559-b21j9sf3 286 5 risk risk NN cord-292559-b21j9sf3 286 6 factors factor NNS cord-292559-b21j9sf3 286 7 , , , cord-292559-b21j9sf3 286 8 such such JJ cord-292559-b21j9sf3 286 9 as as IN cord-292559-b21j9sf3 286 10 chronic chronic JJ cord-292559-b21j9sf3 286 11 stress stress NN cord-292559-b21j9sf3 286 12 and and CC cord-292559-b21j9sf3 286 13 poor poor JJ cord-292559-b21j9sf3 286 14 social social JJ cord-292559-b21j9sf3 286 15 support support NN cord-292559-b21j9sf3 286 16 , , , cord-292559-b21j9sf3 286 17 may may MD cord-292559-b21j9sf3 286 18 be be VB cord-292559-b21j9sf3 286 19 consistently consistently RB cord-292559-b21j9sf3 286 20 associated associate VBN cord-292559-b21j9sf3 286 21 with with IN cord-292559-b21j9sf3 286 22 risk risk NN cord-292559-b21j9sf3 286 23 for for IN cord-292559-b21j9sf3 286 24 depression depression NN cord-292559-b21j9sf3 286 25 across across IN cord-292559-b21j9sf3 286 26 development development NN cord-292559-b21j9sf3 286 27 [ [ -LRB- cord-292559-b21j9sf3 286 28 90 90 CD cord-292559-b21j9sf3 286 29 , , , cord-292559-b21j9sf3 286 30 91 91 CD cord-292559-b21j9sf3 286 31 ] ] -RRB- cord-292559-b21j9sf3 286 32 , , , cord-292559-b21j9sf3 286 33 although although IN cord-292559-b21j9sf3 286 34 the the DT cord-292559-b21j9sf3 286 35 degree degree NN cord-292559-b21j9sf3 286 36 of of IN cord-292559-b21j9sf3 286 37 severity severity NN cord-292559-b21j9sf3 286 38 may may MD cord-292559-b21j9sf3 286 39 be be VB cord-292559-b21j9sf3 286 40 different different JJ cord-292559-b21j9sf3 286 41 in in IN cord-292559-b21j9sf3 286 42 different different JJ cord-292559-b21j9sf3 286 43 development development NN cord-292559-b21j9sf3 286 44 periods period NNS cord-292559-b21j9sf3 286 45 . . . cord-292559-b21j9sf3 287 1 Thus thus RB cord-292559-b21j9sf3 287 2 , , , cord-292559-b21j9sf3 287 3 it -PRON- PRP cord-292559-b21j9sf3 287 4 is be VBZ cord-292559-b21j9sf3 287 5 possible possible JJ cord-292559-b21j9sf3 287 6 that that IN cord-292559-b21j9sf3 287 7 some some DT cord-292559-b21j9sf3 287 8 risk risk NN cord-292559-b21j9sf3 287 9 factors factor NNS cord-292559-b21j9sf3 287 10 first first RB cord-292559-b21j9sf3 287 11 emerge emerge VBP cord-292559-b21j9sf3 287 12 , , , cord-292559-b21j9sf3 287 13 and and CC cord-292559-b21j9sf3 287 14 then then RB cord-292559-b21j9sf3 287 15 accumulate accumulate VB cord-292559-b21j9sf3 287 16 over over IN cord-292559-b21j9sf3 287 17 time time NN cord-292559-b21j9sf3 287 18 , , , cord-292559-b21j9sf3 287 19 versus versus IN cord-292559-b21j9sf3 287 20 others other NNS cord-292559-b21j9sf3 287 21 are be VBP cord-292559-b21j9sf3 287 22 only only RB cord-292559-b21j9sf3 287 23 associated associate VBN cord-292559-b21j9sf3 287 24 with with IN cord-292559-b21j9sf3 287 25 risk risk NN cord-292559-b21j9sf3 287 26 during during IN cord-292559-b21j9sf3 287 27 " " `` cord-292559-b21j9sf3 287 28 critical critical JJ cord-292559-b21j9sf3 287 29 periods period NNS cord-292559-b21j9sf3 287 30 " " '' cord-292559-b21j9sf3 287 31 that that WDT cord-292559-b21j9sf3 287 32 may may MD cord-292559-b21j9sf3 287 33 correspond correspond VB cord-292559-b21j9sf3 287 34 with with IN cord-292559-b21j9sf3 287 35 certain certain JJ cord-292559-b21j9sf3 287 36 maturational maturational JJ cord-292559-b21j9sf3 287 37 changes change NNS cord-292559-b21j9sf3 287 38 . . . cord-292559-b21j9sf3 288 1 Balancing balance VBG cord-292559-b21j9sf3 288 2 large large JJ cord-292559-b21j9sf3 288 3 - - HYPH cord-292559-b21j9sf3 288 4 scale scale NN cord-292559-b21j9sf3 288 5 studies study NNS cord-292559-b21j9sf3 288 6 with with IN cord-292559-b21j9sf3 288 7 deep deep JJ cord-292559-b21j9sf3 288 8 phenotyping phenotyping NN cord-292559-b21j9sf3 288 9 . . . cord-292559-b21j9sf3 289 1 Research research NN cord-292559-b21j9sf3 289 2 is be VBZ cord-292559-b21j9sf3 289 3 increasingly increasingly RB cord-292559-b21j9sf3 289 4 moving move VBG cord-292559-b21j9sf3 289 5 towards towards IN cord-292559-b21j9sf3 289 6 precision precision NN cord-292559-b21j9sf3 289 7 medicine medicine NN cord-292559-b21j9sf3 289 8 efforts effort NNS cord-292559-b21j9sf3 289 9 , , , cord-292559-b21j9sf3 289 10 aiming aim VBG cord-292559-b21j9sf3 289 11 to to TO cord-292559-b21j9sf3 289 12 tailor tailor VB cord-292559-b21j9sf3 289 13 interventions intervention NNS cord-292559-b21j9sf3 289 14 for for IN cord-292559-b21j9sf3 289 15 psychopathology psychopathology NN cord-292559-b21j9sf3 289 16 to to IN cord-292559-b21j9sf3 289 17 the the DT cord-292559-b21j9sf3 289 18 individual individual NN cord-292559-b21j9sf3 289 19 [ [ -LRB- cord-292559-b21j9sf3 289 20 92 92 CD cord-292559-b21j9sf3 289 21 , , , cord-292559-b21j9sf3 289 22 93 93 CD cord-292559-b21j9sf3 289 23 ] ] -RRB- cord-292559-b21j9sf3 289 24 . . . cord-292559-b21j9sf3 290 1 Thus thus RB cord-292559-b21j9sf3 290 2 , , , cord-292559-b21j9sf3 290 3 one one CD cord-292559-b21j9sf3 290 4 potential potential JJ cord-292559-b21j9sf3 290 5 criticism criticism NN cord-292559-b21j9sf3 290 6 of of IN cord-292559-b21j9sf3 290 7 large large JJ cord-292559-b21j9sf3 290 8 - - HYPH cord-292559-b21j9sf3 290 9 scale scale NN cord-292559-b21j9sf3 290 10 population population NN cord-292559-b21j9sf3 290 11 neuroscience neuroscience NN cord-292559-b21j9sf3 290 12 efforts effort NNS cord-292559-b21j9sf3 290 13 is be VBZ cord-292559-b21j9sf3 290 14 the the DT cord-292559-b21j9sf3 290 15 value value NN cord-292559-b21j9sf3 290 16 and and CC cord-292559-b21j9sf3 290 17 utility utility NN cord-292559-b21j9sf3 290 18 of of IN cord-292559-b21j9sf3 290 19 massive massive JJ cord-292559-b21j9sf3 290 20 research research NN cord-292559-b21j9sf3 290 21 efforts effort NNS cord-292559-b21j9sf3 290 22 for for IN cord-292559-b21j9sf3 290 23 precision precision NN cord-292559-b21j9sf3 290 24 medicine medicine NN cord-292559-b21j9sf3 290 25 . . . cord-292559-b21j9sf3 291 1 It -PRON- PRP cord-292559-b21j9sf3 291 2 is be VBZ cord-292559-b21j9sf3 291 3 possible possible JJ cord-292559-b21j9sf3 291 4 that that IN cord-292559-b21j9sf3 291 5 in in IN cord-292559-b21j9sf3 291 6 advancing advance VBG cord-292559-b21j9sf3 291 7 our -PRON- PRP$ cord-292559-b21j9sf3 291 8 understanding understanding NN cord-292559-b21j9sf3 291 9 of of IN cord-292559-b21j9sf3 291 10 the the DT cord-292559-b21j9sf3 291 11 etiology etiology NN cord-292559-b21j9sf3 291 12 of of IN cord-292559-b21j9sf3 291 13 mental mental JJ cord-292559-b21j9sf3 291 14 and and CC cord-292559-b21j9sf3 291 15 physical physical JJ cord-292559-b21j9sf3 291 16 illness illness NN cord-292559-b21j9sf3 291 17 , , , cord-292559-b21j9sf3 291 18 we -PRON- PRP cord-292559-b21j9sf3 291 19 could could MD cord-292559-b21j9sf3 291 20 obscure obscure VB cord-292559-b21j9sf3 291 21 the the DT cord-292559-b21j9sf3 291 22 trees tree NNS cord-292559-b21j9sf3 291 23 for for IN cord-292559-b21j9sf3 291 24 the the DT cord-292559-b21j9sf3 291 25 forest forest NN cord-292559-b21j9sf3 291 26 by by IN cord-292559-b21j9sf3 291 27 examining examine VBG cord-292559-b21j9sf3 291 28 large large JJ cord-292559-b21j9sf3 291 29 - - HYPH cord-292559-b21j9sf3 291 30 scale scale NN cord-292559-b21j9sf3 291 31 efforts effort NNS cord-292559-b21j9sf3 291 32 as as IN cord-292559-b21j9sf3 291 33 opposed oppose VBN cord-292559-b21j9sf3 291 34 to to IN cord-292559-b21j9sf3 291 35 deep deep JJ cord-292559-b21j9sf3 291 36 phenotyping phenotyping NN cord-292559-b21j9sf3 291 37 . . . cord-292559-b21j9sf3 292 1 Deep deep JJ cord-292559-b21j9sf3 292 2 phenotyping phenotyping NN cord-292559-b21j9sf3 292 3 refers refer VBZ cord-292559-b21j9sf3 292 4 to to IN cord-292559-b21j9sf3 292 5 gathering gather VBG cord-292559-b21j9sf3 292 6 details detail NNS cord-292559-b21j9sf3 292 7 about about IN cord-292559-b21j9sf3 292 8 disorder disorder NN cord-292559-b21j9sf3 292 9 manifestations manifestation NNS cord-292559-b21j9sf3 292 10 in in IN cord-292559-b21j9sf3 292 11 a a DT cord-292559-b21j9sf3 292 12 fine fine JJ cord-292559-b21j9sf3 292 13 - - HYPH cord-292559-b21j9sf3 292 14 grained grained JJ cord-292559-b21j9sf3 292 15 manner manner NN cord-292559-b21j9sf3 292 16 to to IN cord-292559-b21j9sf3 292 17 more more RBR cord-292559-b21j9sf3 292 18 precisely precisely RB cord-292559-b21j9sf3 292 19 define define VB cord-292559-b21j9sf3 292 20 phenotypes phenotype NNS cord-292559-b21j9sf3 292 21 [ [ -LRB- cord-292559-b21j9sf3 292 22 94 94 CD cord-292559-b21j9sf3 292 23 ] ] -RRB- cord-292559-b21j9sf3 292 24 , , , cord-292559-b21j9sf3 292 25 as as IN cord-292559-b21j9sf3 292 26 many many JJ cord-292559-b21j9sf3 292 27 phenotypes phenotype NNS cord-292559-b21j9sf3 292 28 currently currently RB cord-292559-b21j9sf3 292 29 fall fall VBP cord-292559-b21j9sf3 292 30 short short RB cord-292559-b21j9sf3 292 31 of of IN cord-292559-b21j9sf3 292 32 fully fully RB cord-292559-b21j9sf3 292 33 capturing capture VBG cord-292559-b21j9sf3 292 34 the the DT cord-292559-b21j9sf3 292 35 diverse diverse JJ cord-292559-b21j9sf3 292 36 manifestations manifestation NNS cord-292559-b21j9sf3 292 37 of of IN cord-292559-b21j9sf3 292 38 the the DT cord-292559-b21j9sf3 292 39 disorder disorder NN cord-292559-b21j9sf3 292 40 ( ( -LRB- cord-292559-b21j9sf3 292 41 e.g. e.g. RB cord-292559-b21j9sf3 292 42 , , , cord-292559-b21j9sf3 292 43 schizophrenia schizophrenia NN cord-292559-b21j9sf3 292 44 , , , cord-292559-b21j9sf3 292 45 ASD ASD NNP cord-292559-b21j9sf3 292 46 ) ) -RRB- cord-292559-b21j9sf3 292 47 . . . cord-292559-b21j9sf3 293 1 However however RB cord-292559-b21j9sf3 293 2 , , , cord-292559-b21j9sf3 293 3 deep deep JJ cord-292559-b21j9sf3 293 4 phenotyping phenotyping NN cord-292559-b21j9sf3 293 5 is be VBZ cord-292559-b21j9sf3 293 6 typically typically RB cord-292559-b21j9sf3 293 7 only only RB cord-292559-b21j9sf3 293 8 possible possible JJ cord-292559-b21j9sf3 293 9 with with IN cord-292559-b21j9sf3 293 10 smaller small JJR cord-292559-b21j9sf3 293 11 samples sample NNS cord-292559-b21j9sf3 293 12 , , , cord-292559-b21j9sf3 293 13 due due IN cord-292559-b21j9sf3 293 14 to to IN cord-292559-b21j9sf3 293 15 the the DT cord-292559-b21j9sf3 293 16 large large JJ cord-292559-b21j9sf3 293 17 amount amount NN cord-292559-b21j9sf3 293 18 of of IN cord-292559-b21j9sf3 293 19 resources resource NNS cord-292559-b21j9sf3 293 20 required require VBN cord-292559-b21j9sf3 293 21 . . . cord-292559-b21j9sf3 294 1 The the DT cord-292559-b21j9sf3 294 2 ABCD ABCD NNP cord-292559-b21j9sf3 294 3 Study Study NNP cord-292559-b21j9sf3 294 4 varies vary VBZ cord-292559-b21j9sf3 294 5 in in IN cord-292559-b21j9sf3 294 6 the the DT cord-292559-b21j9sf3 294 7 depth depth NN cord-292559-b21j9sf3 294 8 of of IN cord-292559-b21j9sf3 294 9 assessment assessment NN cord-292559-b21j9sf3 294 10 across across IN cord-292559-b21j9sf3 294 11 phenotypes phenotype NNS cord-292559-b21j9sf3 294 12 . . . cord-292559-b21j9sf3 295 1 For for IN cord-292559-b21j9sf3 295 2 alcohol alcohol NN cord-292559-b21j9sf3 295 3 and and CC cord-292559-b21j9sf3 295 4 substance substance NN cord-292559-b21j9sf3 295 5 use use NN cord-292559-b21j9sf3 295 6 , , , cord-292559-b21j9sf3 295 7 the the DT cord-292559-b21j9sf3 295 8 ABCD ABCD NNP cord-292559-b21j9sf3 295 9 Study Study NNP cord-292559-b21j9sf3 295 10 uses use VBZ cord-292559-b21j9sf3 295 11 deeper deep JJR cord-292559-b21j9sf3 295 12 phenotyping phenotyping NN cord-292559-b21j9sf3 295 13 , , , cord-292559-b21j9sf3 295 14 with with IN cord-292559-b21j9sf3 295 15 finer fine JJR cord-292559-b21j9sf3 295 16 - - HYPH cord-292559-b21j9sf3 295 17 grained grain VBN cord-292559-b21j9sf3 295 18 data datum NNS cord-292559-b21j9sf3 295 19 on on IN cord-292559-b21j9sf3 295 20 patterns pattern NNS cord-292559-b21j9sf3 295 21 of of IN cord-292559-b21j9sf3 295 22 use use NN cord-292559-b21j9sf3 295 23 , , , cord-292559-b21j9sf3 295 24 including include VBG cord-292559-b21j9sf3 295 25 biospecimen biospecimen NNP cord-292559-b21j9sf3 295 26 collection collection NN cord-292559-b21j9sf3 295 27 , , , cord-292559-b21j9sf3 295 28 youth youth NN cord-292559-b21j9sf3 295 29 and and CC cord-292559-b21j9sf3 295 30 parent parent NN cord-292559-b21j9sf3 295 31 interviews interview NNS cord-292559-b21j9sf3 295 32 of of IN cord-292559-b21j9sf3 295 33 use use NN cord-292559-b21j9sf3 295 34 , , , cord-292559-b21j9sf3 295 35 as as RB cord-292559-b21j9sf3 295 36 well well RB cord-292559-b21j9sf3 295 37 as as IN cord-292559-b21j9sf3 295 38 reports report NNS cord-292559-b21j9sf3 295 39 of of IN cord-292559-b21j9sf3 295 40 peer peer NN cord-292559-b21j9sf3 295 41 use use NN cord-292559-b21j9sf3 295 42 , , , cord-292559-b21j9sf3 295 43 expectancies expectancy NNS cord-292559-b21j9sf3 295 44 , , , cord-292559-b21j9sf3 295 45 and and CC cord-292559-b21j9sf3 295 46 consequences consequence NNS cord-292559-b21j9sf3 295 47 of of IN cord-292559-b21j9sf3 295 48 use use NN cord-292559-b21j9sf3 295 49 . . . cord-292559-b21j9sf3 296 1 Combined combine VBN cord-292559-b21j9sf3 296 2 with with IN cord-292559-b21j9sf3 296 3 collection collection NN cord-292559-b21j9sf3 296 4 of of IN cord-292559-b21j9sf3 296 5 neuroimaging neuroimage VBG cord-292559-b21j9sf3 296 6 and and CC cord-292559-b21j9sf3 296 7 genetic genetic JJ cord-292559-b21j9sf3 296 8 data datum NNS cord-292559-b21j9sf3 296 9 , , , cord-292559-b21j9sf3 296 10 the the DT cord-292559-b21j9sf3 296 11 ABCD ABCD NNP cord-292559-b21j9sf3 296 12 Study Study NNP cord-292559-b21j9sf3 296 13 poses pose VBZ cord-292559-b21j9sf3 296 14 the the DT cord-292559-b21j9sf3 296 15 opportunity opportunity NN cord-292559-b21j9sf3 296 16 to to TO cord-292559-b21j9sf3 296 17 create create VB cord-292559-b21j9sf3 296 18 a a DT cord-292559-b21j9sf3 296 19 nuanced nuanced JJ cord-292559-b21j9sf3 296 20 phenotype phenotype NN cord-292559-b21j9sf3 296 21 of of IN cord-292559-b21j9sf3 296 22 alcohol alcohol NN cord-292559-b21j9sf3 296 23 and and CC cord-292559-b21j9sf3 296 24 substance substance NN cord-292559-b21j9sf3 296 25 use use VBP cord-292559-b21j9sf3 296 26 across across IN cord-292559-b21j9sf3 296 27 adolescence adolescence NN cord-292559-b21j9sf3 296 28 and and CC cord-292559-b21j9sf3 296 29 young young JJ cord-292559-b21j9sf3 296 30 adulthood adulthood NN cord-292559-b21j9sf3 296 31 . . . cord-292559-b21j9sf3 297 1 In in IN cord-292559-b21j9sf3 297 2 contrast contrast NN cord-292559-b21j9sf3 297 3 , , , cord-292559-b21j9sf3 297 4 other other JJ cord-292559-b21j9sf3 297 5 phenotypes phenotype NNS cord-292559-b21j9sf3 297 6 assessed assess VBN cord-292559-b21j9sf3 297 7 in in IN cord-292559-b21j9sf3 297 8 the the DT cord-292559-b21j9sf3 297 9 ABCD ABCD NNP cord-292559-b21j9sf3 297 10 Study Study NNP cord-292559-b21j9sf3 297 11 , , , cord-292559-b21j9sf3 297 12 including include VBG cord-292559-b21j9sf3 297 13 psychosis psychosis NN cord-292559-b21j9sf3 297 14 , , , cord-292559-b21j9sf3 297 15 are be VBP cord-292559-b21j9sf3 297 16 assessed assess VBN cord-292559-b21j9sf3 297 17 with with IN cord-292559-b21j9sf3 297 18 less less JJR cord-292559-b21j9sf3 297 19 fine fine JJ cord-292559-b21j9sf3 297 20 - - HYPH cord-292559-b21j9sf3 297 21 grained grained JJ cord-292559-b21j9sf3 297 22 detail detail NN cord-292559-b21j9sf3 297 23 . . . cord-292559-b21j9sf3 298 1 Nonetheless nonetheless RB cord-292559-b21j9sf3 298 2 , , , cord-292559-b21j9sf3 298 3 the the DT cord-292559-b21j9sf3 298 4 insights insight NNS cord-292559-b21j9sf3 298 5 gained gain VBD cord-292559-b21j9sf3 298 6 from from IN cord-292559-b21j9sf3 298 7 the the DT cord-292559-b21j9sf3 298 8 ABCD ABCD NNP cord-292559-b21j9sf3 298 9 Study Study NNP cord-292559-b21j9sf3 298 10 can can MD cord-292559-b21j9sf3 298 11 be be VB cord-292559-b21j9sf3 298 12 used use VBN cord-292559-b21j9sf3 298 13 to to TO cord-292559-b21j9sf3 298 14 spur spur VB cord-292559-b21j9sf3 298 15 subsequent subsequent JJ cord-292559-b21j9sf3 298 16 deep deep JJ cord-292559-b21j9sf3 298 17 phenotyping phenotyping NN cord-292559-b21j9sf3 298 18 studies study NNS cord-292559-b21j9sf3 298 19 that that WDT cord-292559-b21j9sf3 298 20 can can MD cord-292559-b21j9sf3 298 21 examine examine VB cord-292559-b21j9sf3 298 22 promising promising JJ cord-292559-b21j9sf3 298 23 risk risk NN cord-292559-b21j9sf3 298 24 factors factor NNS cord-292559-b21j9sf3 298 25 and and CC cord-292559-b21j9sf3 298 26 mechanisms mechanism NNS cord-292559-b21j9sf3 298 27 identified identify VBN cord-292559-b21j9sf3 298 28 in in IN cord-292559-b21j9sf3 298 29 the the DT cord-292559-b21j9sf3 298 30 ABCD ABCD NNP cord-292559-b21j9sf3 298 31 Study Study NNP cord-292559-b21j9sf3 298 32 data datum NNS cord-292559-b21j9sf3 298 33 in in IN cord-292559-b21j9sf3 298 34 a a DT cord-292559-b21j9sf3 298 35 more more RBR cord-292559-b21j9sf3 298 36 finegrained finegrained JJ cord-292559-b21j9sf3 298 37 fashion fashion NN cord-292559-b21j9sf3 298 38 in in IN cord-292559-b21j9sf3 298 39 more more RBR cord-292559-b21j9sf3 298 40 tailored tailor VBN cord-292559-b21j9sf3 298 41 populations population NNS cord-292559-b21j9sf3 298 42 . . . cord-292559-b21j9sf3 299 1 Longitudinal longitudinal JJ cord-292559-b21j9sf3 299 2 analyses analysis NNS cord-292559-b21j9sf3 299 3 . . . cord-292559-b21j9sf3 300 1 Given give VBN cord-292559-b21j9sf3 300 2 that that IN cord-292559-b21j9sf3 300 3 the the DT cord-292559-b21j9sf3 300 4 ABCD ABCD NNP cord-292559-b21j9sf3 300 5 Study Study NNP cord-292559-b21j9sf3 300 6 is be VBZ cord-292559-b21j9sf3 300 7 following follow VBG cord-292559-b21j9sf3 300 8 youth youth NN cord-292559-b21j9sf3 300 9 from from IN cord-292559-b21j9sf3 300 10 age age NN cord-292559-b21j9sf3 300 11 9 9 CD cord-292559-b21j9sf3 300 12 to to TO cord-292559-b21j9sf3 300 13 10 10 CD cord-292559-b21j9sf3 300 14 into into IN cord-292559-b21j9sf3 300 15 adulthood adulthood NN cord-292559-b21j9sf3 300 16 , , , cord-292559-b21j9sf3 300 17 one one CD cord-292559-b21j9sf3 300 18 of of IN cord-292559-b21j9sf3 300 19 the the DT cord-292559-b21j9sf3 300 20 most most RBS cord-292559-b21j9sf3 300 21 important important JJ cord-292559-b21j9sf3 300 22 future future JJ cord-292559-b21j9sf3 300 23 directions direction NNS cord-292559-b21j9sf3 300 24 is be VBZ cord-292559-b21j9sf3 300 25 conducting conduct VBG cord-292559-b21j9sf3 300 26 longitudinal longitudinal JJ cord-292559-b21j9sf3 300 27 analyses analysis NNS cord-292559-b21j9sf3 300 28 . . . cord-292559-b21j9sf3 301 1 The the DT cord-292559-b21j9sf3 301 2 fields field NNS cord-292559-b21j9sf3 301 3 of of IN cord-292559-b21j9sf3 301 4 psychology psychology NN cord-292559-b21j9sf3 301 5 and and CC cord-292559-b21j9sf3 301 6 psychiatry psychiatry NN cord-292559-b21j9sf3 301 7 have have VBP cord-292559-b21j9sf3 301 8 made make VBN cord-292559-b21j9sf3 301 9 few few JJ cord-292559-b21j9sf3 301 10 reliable reliable JJ cord-292559-b21j9sf3 301 11 advances advance NNS cord-292559-b21j9sf3 301 12 in in IN cord-292559-b21j9sf3 301 13 understanding understand VBG cord-292559-b21j9sf3 301 14 causal causal NN cord-292559-b21j9sf3 301 15 mechanisms mechanism NNS cord-292559-b21j9sf3 301 16 underlying underlie VBG cord-292559-b21j9sf3 301 17 the the DT cord-292559-b21j9sf3 301 18 development development NN cord-292559-b21j9sf3 301 19 of of IN cord-292559-b21j9sf3 301 20 negative negative JJ cord-292559-b21j9sf3 301 21 mental mental JJ cord-292559-b21j9sf3 301 22 health health NN cord-292559-b21j9sf3 301 23 outcomes outcome NNS cord-292559-b21j9sf3 301 24 , , , cord-292559-b21j9sf3 301 25 including include VBG cord-292559-b21j9sf3 301 26 substance substance NN cord-292559-b21j9sf3 301 27 use use VBP cord-292559-b21j9sf3 301 28 disorders disorder NNS cord-292559-b21j9sf3 301 29 and and CC cord-292559-b21j9sf3 301 30 psychosis psychosis NN cord-292559-b21j9sf3 301 31 [ [ -LRB- cord-292559-b21j9sf3 301 32 95 95 CD cord-292559-b21j9sf3 301 33 ] ] -RRB- cord-292559-b21j9sf3 301 34 . . . cord-292559-b21j9sf3 302 1 Following follow VBG cord-292559-b21j9sf3 302 2 a a DT cord-292559-b21j9sf3 302 3 cohort cohort NN cord-292559-b21j9sf3 302 4 of of IN cord-292559-b21j9sf3 302 5 youth youth NN cord-292559-b21j9sf3 302 6 through through IN cord-292559-b21j9sf3 302 7 a a DT cord-292559-b21j9sf3 302 8 period period NN cord-292559-b21j9sf3 302 9 of of IN cord-292559-b21j9sf3 302 10 significant significant JJ cord-292559-b21j9sf3 302 11 risk risk NN cord-292559-b21j9sf3 302 12 will will MD cord-292559-b21j9sf3 302 13 provide provide VB cord-292559-b21j9sf3 302 14 important important JJ cord-292559-b21j9sf3 302 15 information information NN cord-292559-b21j9sf3 302 16 about about IN cord-292559-b21j9sf3 302 17 what what WP cord-292559-b21j9sf3 302 18 trajectories trajectory NNS cord-292559-b21j9sf3 302 19 of of IN cord-292559-b21j9sf3 302 20 risk risk NN cord-292559-b21j9sf3 302 21 factors factor NNS cord-292559-b21j9sf3 302 22 significantly significantly RB cord-292559-b21j9sf3 302 23 predict predict VBP cord-292559-b21j9sf3 302 24 transition transition NN cord-292559-b21j9sf3 302 25 to to IN cord-292559-b21j9sf3 302 26 negative negative JJ cord-292559-b21j9sf3 302 27 mental mental JJ cord-292559-b21j9sf3 302 28 and and CC cord-292559-b21j9sf3 302 29 physical physical JJ cord-292559-b21j9sf3 302 30 health health NN cord-292559-b21j9sf3 302 31 outcomes outcome NNS cord-292559-b21j9sf3 302 32 . . . cord-292559-b21j9sf3 303 1 Through through IN cord-292559-b21j9sf3 303 2 examining examine VBG cord-292559-b21j9sf3 303 3 trajectories trajectory NNS cord-292559-b21j9sf3 303 4 of of IN cord-292559-b21j9sf3 303 5 neural neural JJ cord-292559-b21j9sf3 303 6 , , , cord-292559-b21j9sf3 303 7 cognitive cognitive JJ cord-292559-b21j9sf3 303 8 , , , cord-292559-b21j9sf3 303 9 social social JJ cord-292559-b21j9sf3 303 10 , , , cord-292559-b21j9sf3 303 11 emotional emotional JJ cord-292559-b21j9sf3 303 12 , , , cord-292559-b21j9sf3 303 13 school school NN cord-292559-b21j9sf3 303 14 , , , cord-292559-b21j9sf3 303 15 and and CC cord-292559-b21j9sf3 303 16 hormonal hormonal JJ cord-292559-b21j9sf3 303 17 functioning functioning NN cord-292559-b21j9sf3 303 18 , , , cord-292559-b21j9sf3 303 19 the the DT cord-292559-b21j9sf3 303 20 ABCD ABCD NNP cord-292559-b21j9sf3 303 21 Study Study NNP cord-292559-b21j9sf3 303 22 will will MD cord-292559-b21j9sf3 303 23 be be VB cord-292559-b21j9sf3 303 24 able able JJ cord-292559-b21j9sf3 303 25 to to TO cord-292559-b21j9sf3 303 26 isolate isolate VB cord-292559-b21j9sf3 303 27 factors factor NNS cord-292559-b21j9sf3 303 28 reliably reliably RB cord-292559-b21j9sf3 303 29 predicting predict VBG cord-292559-b21j9sf3 303 30 typical typical JJ cord-292559-b21j9sf3 303 31 versus versus IN cord-292559-b21j9sf3 303 32 atypical atypical JJ cord-292559-b21j9sf3 303 33 development development NN cord-292559-b21j9sf3 303 34 from from IN cord-292559-b21j9sf3 303 35 middle middle JJ cord-292559-b21j9sf3 303 36 childhood childhood NN cord-292559-b21j9sf3 303 37 into into IN cord-292559-b21j9sf3 303 38 young young JJ cord-292559-b21j9sf3 303 39 adulthood adulthood NN cord-292559-b21j9sf3 303 40 [ [ -LRB- cord-292559-b21j9sf3 303 41 3 3 CD cord-292559-b21j9sf3 303 42 ] ] -RRB- cord-292559-b21j9sf3 303 43 . . . cord-292559-b21j9sf3 304 1 This this DT cord-292559-b21j9sf3 304 2 ten ten CD cord-292559-b21j9sf3 304 3 - - HYPH cord-292559-b21j9sf3 304 4 year year NN cord-292559-b21j9sf3 304 5 study study NN cord-292559-b21j9sf3 304 6 sets set VBZ cord-292559-b21j9sf3 304 7 the the DT cord-292559-b21j9sf3 304 8 stage stage NN cord-292559-b21j9sf3 304 9 for for IN cord-292559-b21j9sf3 304 10 several several JJ cord-292559-b21j9sf3 304 11 potential potential JJ cord-292559-b21j9sf3 304 12 avenues avenue NNS cord-292559-b21j9sf3 304 13 for for IN cord-292559-b21j9sf3 304 14 longitudinal longitudinal JJ cord-292559-b21j9sf3 304 15 research research NN cord-292559-b21j9sf3 304 16 , , , cord-292559-b21j9sf3 304 17 helping help VBG cord-292559-b21j9sf3 304 18 to to TO cord-292559-b21j9sf3 304 19 answer answer VB cord-292559-b21j9sf3 304 20 fundamental fundamental JJ cord-292559-b21j9sf3 304 21 questions question NNS cord-292559-b21j9sf3 304 22 about about IN cord-292559-b21j9sf3 304 23 the the DT cord-292559-b21j9sf3 304 24 effects effect NNS cord-292559-b21j9sf3 304 25 of of IN cord-292559-b21j9sf3 304 26 the the DT cord-292559-b21j9sf3 304 27 onset onset NN cord-292559-b21j9sf3 304 28 and and CC cord-292559-b21j9sf3 304 29 progression progression NN cord-292559-b21j9sf3 304 30 of of IN cord-292559-b21j9sf3 304 31 symptoms symptom NNS cord-292559-b21j9sf3 304 32 of of IN cord-292559-b21j9sf3 304 33 psychopathology psychopathology NN cord-292559-b21j9sf3 304 34 [ [ -LRB- cord-292559-b21j9sf3 304 35 8 8 CD cord-292559-b21j9sf3 304 36 ] ] -RRB- cord-292559-b21j9sf3 304 37 . . . cord-292559-b21j9sf3 305 1 A a DT cord-292559-b21j9sf3 305 2 major major JJ cord-292559-b21j9sf3 305 3 aim aim NN cord-292559-b21j9sf3 305 4 of of IN cord-292559-b21j9sf3 305 5 the the DT cord-292559-b21j9sf3 305 6 ABCD ABCD NNP cord-292559-b21j9sf3 305 7 Study Study NNP cord-292559-b21j9sf3 305 8 is be VBZ cord-292559-b21j9sf3 305 9 to to TO cord-292559-b21j9sf3 305 10 longitudinally longitudinally RB cord-292559-b21j9sf3 305 11 examine examine VB cord-292559-b21j9sf3 305 12 the the DT cord-292559-b21j9sf3 305 13 neurodevelopmental neurodevelopmental JJ cord-292559-b21j9sf3 305 14 and and CC cord-292559-b21j9sf3 305 15 behavioral behavioral JJ cord-292559-b21j9sf3 305 16 effects effect NNS cord-292559-b21j9sf3 305 17 of of IN cord-292559-b21j9sf3 305 18 substance substance NN cord-292559-b21j9sf3 305 19 use use NN cord-292559-b21j9sf3 305 20 . . . cord-292559-b21j9sf3 306 1 By by IN cord-292559-b21j9sf3 306 2 analyzing analyze VBG cord-292559-b21j9sf3 306 3 development development NN cord-292559-b21j9sf3 306 4 both both CC cord-292559-b21j9sf3 306 5 preexposure preexposure NN cord-292559-b21j9sf3 306 6 and and CC cord-292559-b21j9sf3 306 7 post post JJ cord-292559-b21j9sf3 306 8 - - NN cord-292559-b21j9sf3 306 9 exposure exposure NN cord-292559-b21j9sf3 306 10 , , , cord-292559-b21j9sf3 306 11 researchers researcher NNS cord-292559-b21j9sf3 306 12 will will MD cord-292559-b21j9sf3 306 13 be be VB cord-292559-b21j9sf3 306 14 able able JJ cord-292559-b21j9sf3 306 15 to to TO cord-292559-b21j9sf3 306 16 clarify clarify VB cord-292559-b21j9sf3 306 17 associations association NNS cord-292559-b21j9sf3 306 18 between between IN cord-292559-b21j9sf3 306 19 substance substance NN cord-292559-b21j9sf3 306 20 use use NN cord-292559-b21j9sf3 306 21 and and CC cord-292559-b21j9sf3 306 22 outcomes outcome NNS cord-292559-b21j9sf3 306 23 , , , cord-292559-b21j9sf3 306 24 including include VBG cord-292559-b21j9sf3 306 25 neurodevelopmental neurodevelopmental JJ cord-292559-b21j9sf3 306 26 , , , cord-292559-b21j9sf3 306 27 neural neural JJ cord-292559-b21j9sf3 306 28 , , , cord-292559-b21j9sf3 306 29 behavioral behavioral JJ cord-292559-b21j9sf3 306 30 , , , cord-292559-b21j9sf3 306 31 and and CC cord-292559-b21j9sf3 306 32 cognitive cognitive NNP cord-292559-b21j9sf3 306 33 correlates correlate NNS cord-292559-b21j9sf3 306 34 [ [ -LRB- cord-292559-b21j9sf3 306 35 3 3 CD cord-292559-b21j9sf3 306 36 , , , cord-292559-b21j9sf3 306 37 7 7 CD cord-292559-b21j9sf3 306 38 , , , cord-292559-b21j9sf3 306 39 8 8 CD cord-292559-b21j9sf3 306 40 ] ] -RRB- cord-292559-b21j9sf3 306 41 . . . cord-292559-b21j9sf3 307 1 Another another DT cord-292559-b21j9sf3 307 2 aim aim NN cord-292559-b21j9sf3 307 3 of of IN cord-292559-b21j9sf3 307 4 the the DT cord-292559-b21j9sf3 307 5 ABCD ABCD NNP cord-292559-b21j9sf3 307 6 Study Study NNP cord-292559-b21j9sf3 307 7 is be VBZ cord-292559-b21j9sf3 307 8 to to TO cord-292559-b21j9sf3 307 9 longitudinally longitudinally RB cord-292559-b21j9sf3 307 10 examine examine VB cord-292559-b21j9sf3 307 11 factors factor NNS cord-292559-b21j9sf3 307 12 , , , cord-292559-b21j9sf3 307 13 including include VBG cord-292559-b21j9sf3 307 14 social social JJ cord-292559-b21j9sf3 307 15 and and CC cord-292559-b21j9sf3 307 16 neurobiological neurobiological JJ cord-292559-b21j9sf3 307 17 , , , cord-292559-b21j9sf3 307 18 that that WDT cord-292559-b21j9sf3 307 19 might may MD cord-292559-b21j9sf3 307 20 contribute contribute VB cord-292559-b21j9sf3 307 21 to to IN cord-292559-b21j9sf3 307 22 resiliency resiliency NN cord-292559-b21j9sf3 307 23 either either CC cord-292559-b21j9sf3 307 24 from from IN cord-292559-b21j9sf3 307 25 engaging engage VBG cord-292559-b21j9sf3 307 26 in in IN cord-292559-b21j9sf3 307 27 substance substance NN cord-292559-b21j9sf3 307 28 use use NN cord-292559-b21j9sf3 307 29 or or CC cord-292559-b21j9sf3 307 30 from from IN cord-292559-b21j9sf3 307 31 negative negative JJ cord-292559-b21j9sf3 307 32 outcomes outcome NNS cord-292559-b21j9sf3 307 33 after after IN cord-292559-b21j9sf3 307 34 initiation initiation NN cord-292559-b21j9sf3 307 35 [ [ -LRB- cord-292559-b21j9sf3 307 36 3 3 CD cord-292559-b21j9sf3 307 37 ] ] -RRB- cord-292559-b21j9sf3 307 38 . . . cord-292559-b21j9sf3 308 1 This this DT cord-292559-b21j9sf3 308 2 information information NN cord-292559-b21j9sf3 308 3 will will MD cord-292559-b21j9sf3 308 4 be be VB cord-292559-b21j9sf3 308 5 critical critical JJ cord-292559-b21j9sf3 308 6 for for IN cord-292559-b21j9sf3 308 7 intervention intervention NN cord-292559-b21j9sf3 308 8 development development NN cord-292559-b21j9sf3 308 9 , , , cord-292559-b21j9sf3 308 10 including include VBG cord-292559-b21j9sf3 308 11 offering offer VBG cord-292559-b21j9sf3 308 12 potential potential JJ cord-292559-b21j9sf3 308 13 avenues avenue NNS cord-292559-b21j9sf3 308 14 to to TO cord-292559-b21j9sf3 308 15 mitigate mitigate VB cord-292559-b21j9sf3 308 16 risk risk NN cord-292559-b21j9sf3 308 17 . . . cord-292559-b21j9sf3 309 1 Thus thus RB cord-292559-b21j9sf3 309 2 , , , cord-292559-b21j9sf3 309 3 longitudinal longitudinal JJ cord-292559-b21j9sf3 309 4 analyses analysis NNS cord-292559-b21j9sf3 309 5 in in IN cord-292559-b21j9sf3 309 6 the the DT cord-292559-b21j9sf3 309 7 ABCD ABCD NNP cord-292559-b21j9sf3 309 8 Study Study NNP cord-292559-b21j9sf3 309 9 will will MD cord-292559-b21j9sf3 309 10 enable enable VB cord-292559-b21j9sf3 309 11 the the DT cord-292559-b21j9sf3 309 12 examination examination NN cord-292559-b21j9sf3 309 13 of of IN cord-292559-b21j9sf3 309 14 trajectories trajectory NNS cord-292559-b21j9sf3 309 15 associated associate VBN cord-292559-b21j9sf3 309 16 with with IN cord-292559-b21j9sf3 309 17 the the DT cord-292559-b21j9sf3 309 18 onset onset NN cord-292559-b21j9sf3 309 19 and and CC cord-292559-b21j9sf3 309 20 progression progression NN cord-292559-b21j9sf3 309 21 of of IN cord-292559-b21j9sf3 309 22 , , , cord-292559-b21j9sf3 309 23 as as RB cord-292559-b21j9sf3 309 24 well well RB cord-292559-b21j9sf3 309 25 as as IN cord-292559-b21j9sf3 309 26 resiliency resiliency NN cord-292559-b21j9sf3 309 27 from from IN cord-292559-b21j9sf3 309 28 , , , cord-292559-b21j9sf3 309 29 psychopathology psychopathology NN cord-292559-b21j9sf3 309 30 and and CC cord-292559-b21j9sf3 309 31 substance substance NN cord-292559-b21j9sf3 309 32 use use NN cord-292559-b21j9sf3 309 33 . . . cord-292559-b21j9sf3 310 1 Passive passive JJ cord-292559-b21j9sf3 310 2 data data NN cord-292559-b21j9sf3 310 3 sampling sampling NN cord-292559-b21j9sf3 310 4 . . . cord-292559-b21j9sf3 311 1 Several several JJ cord-292559-b21j9sf3 311 2 passive passive JJ cord-292559-b21j9sf3 311 3 data data NN cord-292559-b21j9sf3 311 4 collection collection NN cord-292559-b21j9sf3 311 5 methods method NNS cord-292559-b21j9sf3 311 6 , , , cord-292559-b21j9sf3 311 7 or or CC cord-292559-b21j9sf3 311 8 data data NN cord-292559-b21j9sf3 311 9 collection collection NN cord-292559-b21j9sf3 311 10 methods method NNS cord-292559-b21j9sf3 311 11 that that WDT cord-292559-b21j9sf3 311 12 do do VBP cord-292559-b21j9sf3 311 13 not not RB cord-292559-b21j9sf3 311 14 require require VB cord-292559-b21j9sf3 311 15 active active JJ cord-292559-b21j9sf3 311 16 responses response NNS cord-292559-b21j9sf3 311 17 from from IN cord-292559-b21j9sf3 311 18 participants participant NNS cord-292559-b21j9sf3 311 19 but but CC cord-292559-b21j9sf3 311 20 instead instead RB cord-292559-b21j9sf3 311 21 collect collect VB cord-292559-b21j9sf3 311 22 data datum NNS cord-292559-b21j9sf3 311 23 from from IN cord-292559-b21j9sf3 311 24 the the DT cord-292559-b21j9sf3 311 25 participant participant NN cord-292559-b21j9sf3 311 26 , , , cord-292559-b21j9sf3 311 27 will will MD cord-292559-b21j9sf3 311 28 become become VB cord-292559-b21j9sf3 311 29 available available JJ cord-292559-b21j9sf3 311 30 in in IN cord-292559-b21j9sf3 311 31 future future JJ cord-292559-b21j9sf3 311 32 ABCD ABCD NNP cord-292559-b21j9sf3 311 33 Study Study NNP cord-292559-b21j9sf3 311 34 assessment assessment NN cord-292559-b21j9sf3 311 35 waves wave NNS cord-292559-b21j9sf3 311 36 [ [ -LRB- cord-292559-b21j9sf3 311 37 96 96 CD cord-292559-b21j9sf3 311 38 ] ] -RRB- cord-292559-b21j9sf3 311 39 . . . cord-292559-b21j9sf3 312 1 Passive passive JJ cord-292559-b21j9sf3 312 2 data datum NNS cord-292559-b21j9sf3 312 3 collection collection NN cord-292559-b21j9sf3 312 4 can can MD cord-292559-b21j9sf3 312 5 be be VB cord-292559-b21j9sf3 312 6 a a DT cord-292559-b21j9sf3 312 7 critical critical JJ cord-292559-b21j9sf3 312 8 tool tool NN cord-292559-b21j9sf3 312 9 for for IN cord-292559-b21j9sf3 312 10 large large JJ cord-292559-b21j9sf3 312 11 - - HYPH cord-292559-b21j9sf3 312 12 scale scale NN cord-292559-b21j9sf3 312 13 studies study NNS cord-292559-b21j9sf3 312 14 , , , cord-292559-b21j9sf3 312 15 as as IN cord-292559-b21j9sf3 312 16 it -PRON- PRP cord-292559-b21j9sf3 312 17 enables enable VBZ cord-292559-b21j9sf3 312 18 additional additional JJ cord-292559-b21j9sf3 312 19 data datum NNS cord-292559-b21j9sf3 312 20 without without IN cord-292559-b21j9sf3 312 21 additional additional JJ cord-292559-b21j9sf3 312 22 burden burden NN cord-292559-b21j9sf3 312 23 . . . cord-292559-b21j9sf3 313 1 The the DT cord-292559-b21j9sf3 313 2 ABCD ABCD NNP cord-292559-b21j9sf3 313 3 Study Study NNP cord-292559-b21j9sf3 313 4 is be VBZ cord-292559-b21j9sf3 313 5 conducting conduct VBG cord-292559-b21j9sf3 313 6 passive passive JJ cord-292559-b21j9sf3 313 7 data data NN cord-292559-b21j9sf3 313 8 collection collection NN cord-292559-b21j9sf3 313 9 from from IN cord-292559-b21j9sf3 313 10 mobile mobile JJ cord-292559-b21j9sf3 313 11 devices device NNS cord-292559-b21j9sf3 313 12 and and CC cord-292559-b21j9sf3 313 13 wearables wearable NNS cord-292559-b21j9sf3 313 14 ( ( -LRB- cord-292559-b21j9sf3 313 15 i.e. i.e. FW cord-292559-b21j9sf3 313 16 , , , cord-292559-b21j9sf3 313 17 Fitbits Fitbits NNP cord-292559-b21j9sf3 313 18 ) ) -RRB- cord-292559-b21j9sf3 313 19 . . . cord-292559-b21j9sf3 314 1 Mobile mobile JJ cord-292559-b21j9sf3 314 2 and and CC cord-292559-b21j9sf3 314 3 wearable wearable JJ cord-292559-b21j9sf3 314 4 technologies technology NNS cord-292559-b21j9sf3 314 5 can can MD cord-292559-b21j9sf3 314 6 capture capture VB cord-292559-b21j9sf3 314 7 information information NN cord-292559-b21j9sf3 314 8 about about IN cord-292559-b21j9sf3 314 9 participants participant NNS cord-292559-b21j9sf3 314 10 that that WDT cord-292559-b21j9sf3 314 11 is be VBZ cord-292559-b21j9sf3 314 12 unable unable JJ cord-292559-b21j9sf3 314 13 to to TO cord-292559-b21j9sf3 314 14 be be VB cord-292559-b21j9sf3 314 15 adequately adequately RB cord-292559-b21j9sf3 314 16 captured capture VBN cord-292559-b21j9sf3 314 17 through through IN cord-292559-b21j9sf3 314 18 self self NN cord-292559-b21j9sf3 314 19 - - HYPH cord-292559-b21j9sf3 314 20 report report NN cord-292559-b21j9sf3 314 21 , , , cord-292559-b21j9sf3 314 22 including include VBG cord-292559-b21j9sf3 314 23 precision precision NN cord-292559-b21j9sf3 314 24 regarding regard VBG cord-292559-b21j9sf3 314 25 social social JJ cord-292559-b21j9sf3 314 26 interactions interaction NNS cord-292559-b21j9sf3 314 27 , , , cord-292559-b21j9sf3 314 28 sleep sleep VB cord-292559-b21j9sf3 314 29 quality quality NN cord-292559-b21j9sf3 314 30 , , , cord-292559-b21j9sf3 314 31 and and CC cord-292559-b21j9sf3 314 32 activity activity NN cord-292559-b21j9sf3 314 33 levels level NNS cord-292559-b21j9sf3 314 34 . . . cord-292559-b21j9sf3 315 1 One one CD cord-292559-b21j9sf3 315 2 exciting exciting JJ cord-292559-b21j9sf3 315 3 avenue avenue NN cord-292559-b21j9sf3 315 4 for for IN cord-292559-b21j9sf3 315 5 passive passive JJ cord-292559-b21j9sf3 315 6 data datum NNS cord-292559-b21j9sf3 315 7 sampling sampling NN cord-292559-b21j9sf3 315 8 is be VBZ cord-292559-b21j9sf3 315 9 understanding understand VBG cord-292559-b21j9sf3 315 10 the the DT cord-292559-b21j9sf3 315 11 role role NN cord-292559-b21j9sf3 315 12 of of IN cord-292559-b21j9sf3 315 13 social social JJ cord-292559-b21j9sf3 315 14 media medium NNS cord-292559-b21j9sf3 315 15 usage usage NN cord-292559-b21j9sf3 315 16 as as IN cord-292559-b21j9sf3 315 17 either either DT cord-292559-b21j9sf3 315 18 risk risk NN cord-292559-b21j9sf3 315 19 or or CC cord-292559-b21j9sf3 315 20 resilience resilience NN cord-292559-b21j9sf3 315 21 markers marker NNS cord-292559-b21j9sf3 315 22 for for IN cord-292559-b21j9sf3 315 23 physical physical JJ cord-292559-b21j9sf3 315 24 and and CC cord-292559-b21j9sf3 315 25 mental mental JJ cord-292559-b21j9sf3 315 26 health health NN cord-292559-b21j9sf3 315 27 outcomes outcome NNS cord-292559-b21j9sf3 315 28 , , , cord-292559-b21j9sf3 315 29 including include VBG cord-292559-b21j9sf3 315 30 substance substance NN cord-292559-b21j9sf3 315 31 use use NN cord-292559-b21j9sf3 315 32 . . . cord-292559-b21j9sf3 316 1 Social social JJ cord-292559-b21j9sf3 316 2 media medium NNS cord-292559-b21j9sf3 316 3 use use NN cord-292559-b21j9sf3 316 4 has have VBZ cord-292559-b21j9sf3 316 5 been be VBN cord-292559-b21j9sf3 316 6 linked link VBN cord-292559-b21j9sf3 316 7 to to IN cord-292559-b21j9sf3 316 8 psychopathology psychopathology NN cord-292559-b21j9sf3 316 9 in in IN cord-292559-b21j9sf3 316 10 adolescents adolescent NNS cord-292559-b21j9sf3 316 11 , , , cord-292559-b21j9sf3 316 12 including include VBG cord-292559-b21j9sf3 316 13 higher high JJR cord-292559-b21j9sf3 316 14 symptoms symptom NNS cord-292559-b21j9sf3 316 15 of of IN cord-292559-b21j9sf3 316 16 depression depression NN cord-292559-b21j9sf3 316 17 and and CC cord-292559-b21j9sf3 316 18 anxiety anxiety NN cord-292559-b21j9sf3 316 19 [ [ -LRB- cord-292559-b21j9sf3 316 20 97 97 CD cord-292559-b21j9sf3 316 21 ] ] -RRB- cord-292559-b21j9sf3 316 22 . . . cord-292559-b21j9sf3 317 1 However however RB cord-292559-b21j9sf3 317 2 , , , cord-292559-b21j9sf3 317 3 previous previous JJ cord-292559-b21j9sf3 317 4 research research NN cord-292559-b21j9sf3 317 5 has have VBZ cord-292559-b21j9sf3 317 6 not not RB cord-292559-b21j9sf3 317 7 established establish VBN cord-292559-b21j9sf3 317 8 screen screen NN cord-292559-b21j9sf3 317 9 time time NN cord-292559-b21j9sf3 317 10 as as IN cord-292559-b21j9sf3 317 11 a a DT cord-292559-b21j9sf3 317 12 causal causal JJ cord-292559-b21j9sf3 317 13 factor factor NN cord-292559-b21j9sf3 317 14 in in IN cord-292559-b21j9sf3 317 15 the the DT cord-292559-b21j9sf3 317 16 development development NN cord-292559-b21j9sf3 317 17 of of IN cord-292559-b21j9sf3 317 18 mental mental JJ cord-292559-b21j9sf3 317 19 health health NN cord-292559-b21j9sf3 317 20 outcomes outcome NNS cord-292559-b21j9sf3 317 21 , , , cord-292559-b21j9sf3 317 22 or or CC cord-292559-b21j9sf3 317 23 whether whether IN cord-292559-b21j9sf3 317 24 altered alter VBN cord-292559-b21j9sf3 317 25 social social JJ cord-292559-b21j9sf3 317 26 media medium NNS cord-292559-b21j9sf3 317 27 use use NN cord-292559-b21j9sf3 317 28 and and CC cord-292559-b21j9sf3 317 29 screen screen NN cord-292559-b21j9sf3 317 30 time time NN cord-292559-b21j9sf3 317 31 are be VBP cord-292559-b21j9sf3 317 32 a a DT cord-292559-b21j9sf3 317 33 correlate correlate JJ cord-292559-b21j9sf3 317 34 or or CC cord-292559-b21j9sf3 317 35 consequence consequence NN cord-292559-b21j9sf3 317 36 of of IN cord-292559-b21j9sf3 317 37 the the DT cord-292559-b21j9sf3 317 38 development development NN cord-292559-b21j9sf3 317 39 of of IN cord-292559-b21j9sf3 317 40 psychopathology psychopathology NN cord-292559-b21j9sf3 317 41 [ [ -LRB- cord-292559-b21j9sf3 317 42 98 98 CD cord-292559-b21j9sf3 317 43 ] ] -RRB- cord-292559-b21j9sf3 317 44 . . . cord-292559-b21j9sf3 318 1 As as IN cord-292559-b21j9sf3 318 2 noted note VBN cord-292559-b21j9sf3 318 3 above above RB cord-292559-b21j9sf3 318 4 , , , cord-292559-b21j9sf3 318 5 starting start VBG cord-292559-b21j9sf3 318 6 at at IN cord-292559-b21j9sf3 318 7 year year NN cord-292559-b21j9sf3 318 8 2 2 CD cord-292559-b21j9sf3 318 9 , , , cord-292559-b21j9sf3 318 10 the the DT cord-292559-b21j9sf3 318 11 ABCD ABCD NNP cord-292559-b21j9sf3 318 12 Study Study NNP cord-292559-b21j9sf3 318 13 is be VBZ cord-292559-b21j9sf3 318 14 also also RB cord-292559-b21j9sf3 318 15 using use VBG cord-292559-b21j9sf3 318 16 accelerometers accelerometer NNS cord-292559-b21j9sf3 318 17 ( ( -LRB- cord-292559-b21j9sf3 318 18 i.e. i.e. FW cord-292559-b21j9sf3 318 19 , , , cord-292559-b21j9sf3 318 20 Fitbits Fitbits NNP cord-292559-b21j9sf3 318 21 ) ) -RRB- cord-292559-b21j9sf3 318 22 to to TO cord-292559-b21j9sf3 318 23 examine examine VB cord-292559-b21j9sf3 318 24 sleep sleep NN cord-292559-b21j9sf3 318 25 quality quality NN cord-292559-b21j9sf3 318 26 and and CC cord-292559-b21j9sf3 318 27 activity activity NN cord-292559-b21j9sf3 318 28 levels level NNS cord-292559-b21j9sf3 318 29 . . . cord-292559-b21j9sf3 319 1 A a DT cord-292559-b21j9sf3 319 2 wealth wealth NN cord-292559-b21j9sf3 319 3 of of IN cord-292559-b21j9sf3 319 4 research research NN cord-292559-b21j9sf3 319 5 links link VBZ cord-292559-b21j9sf3 319 6 poor poor JJ cord-292559-b21j9sf3 319 7 sleep sleep NN cord-292559-b21j9sf3 319 8 quality quality NN cord-292559-b21j9sf3 319 9 to to IN cord-292559-b21j9sf3 319 10 negative negative JJ cord-292559-b21j9sf3 319 11 physical physical JJ cord-292559-b21j9sf3 319 12 and and CC cord-292559-b21j9sf3 319 13 mental mental JJ cord-292559-b21j9sf3 319 14 health health NN cord-292559-b21j9sf3 319 15 outcomes outcome NNS cord-292559-b21j9sf3 319 16 [ [ -LRB- cord-292559-b21j9sf3 319 17 99 99 CD cord-292559-b21j9sf3 319 18 , , , cord-292559-b21j9sf3 319 19 100 100 CD cord-292559-b21j9sf3 319 20 ] ] -RRB- cord-292559-b21j9sf3 319 21 . . . cord-292559-b21j9sf3 320 1 The the DT cord-292559-b21j9sf3 320 2 examination examination NN cord-292559-b21j9sf3 320 3 of of IN cord-292559-b21j9sf3 320 4 variables variable NNS cord-292559-b21j9sf3 320 5 such such JJ cord-292559-b21j9sf3 320 6 as as IN cord-292559-b21j9sf3 320 7 sleep sleep NN cord-292559-b21j9sf3 320 8 quality quality NN cord-292559-b21j9sf3 320 9 over over IN cord-292559-b21j9sf3 320 10 time time NN cord-292559-b21j9sf3 320 11 will will MD cord-292559-b21j9sf3 320 12 begin begin VB cord-292559-b21j9sf3 320 13 to to TO cord-292559-b21j9sf3 320 14 disentangle disentangle VB cord-292559-b21j9sf3 320 15 causality causality NN cord-292559-b21j9sf3 320 16 , , , cord-292559-b21j9sf3 320 17 such such JJ cord-292559-b21j9sf3 320 18 as as IN cord-292559-b21j9sf3 320 19 whether whether IN cord-292559-b21j9sf3 320 20 poor poor JJ cord-292559-b21j9sf3 320 21 sleep sleep NN cord-292559-b21j9sf3 320 22 is be VBZ cord-292559-b21j9sf3 320 23 a a DT cord-292559-b21j9sf3 320 24 cause cause NN cord-292559-b21j9sf3 320 25 or or CC cord-292559-b21j9sf3 320 26 a a DT cord-292559-b21j9sf3 320 27 consequence consequence NN cord-292559-b21j9sf3 320 28 of of IN cord-292559-b21j9sf3 320 29 negative negative JJ cord-292559-b21j9sf3 320 30 mental mental JJ cord-292559-b21j9sf3 320 31 and and CC cord-292559-b21j9sf3 320 32 physical physical JJ cord-292559-b21j9sf3 320 33 health health NN cord-292559-b21j9sf3 320 34 outcomes outcome NNS cord-292559-b21j9sf3 320 35 . . . cord-292559-b21j9sf3 321 1 Likewise likewise RB cord-292559-b21j9sf3 321 2 , , , cord-292559-b21j9sf3 321 3 increased increase VBN cord-292559-b21j9sf3 321 4 physical physical JJ cord-292559-b21j9sf3 321 5 activity activity NN cord-292559-b21j9sf3 321 6 is be VBZ cord-292559-b21j9sf3 321 7 a a DT cord-292559-b21j9sf3 321 8 protective protective JJ cord-292559-b21j9sf3 321 9 factor factor NN cord-292559-b21j9sf3 321 10 for for IN cord-292559-b21j9sf3 321 11 a a DT cord-292559-b21j9sf3 321 12 number number NN cord-292559-b21j9sf3 321 13 of of IN cord-292559-b21j9sf3 321 14 positive positive JJ cord-292559-b21j9sf3 321 15 physical physical JJ cord-292559-b21j9sf3 321 16 and and CC cord-292559-b21j9sf3 321 17 mental mental JJ cord-292559-b21j9sf3 321 18 health health NN cord-292559-b21j9sf3 321 19 outcomes outcome NNS cord-292559-b21j9sf3 321 20 , , , cord-292559-b21j9sf3 321 21 including include VBG cord-292559-b21j9sf3 321 22 maintaining maintain VBG cord-292559-b21j9sf3 321 23 a a DT cord-292559-b21j9sf3 321 24 healthy healthy JJ cord-292559-b21j9sf3 321 25 weight weight NN cord-292559-b21j9sf3 321 26 and and CC cord-292559-b21j9sf3 321 27 lessened lessen VBD cord-292559-b21j9sf3 321 28 risk risk NN cord-292559-b21j9sf3 321 29 of of IN cord-292559-b21j9sf3 321 30 depressive depressive JJ cord-292559-b21j9sf3 321 31 symptoms symptom NNS cord-292559-b21j9sf3 321 32 [ [ -LRB- cord-292559-b21j9sf3 321 33 89 89 CD cord-292559-b21j9sf3 321 34 , , , cord-292559-b21j9sf3 321 35 101 101 CD cord-292559-b21j9sf3 321 36 ] ] -RRB- cord-292559-b21j9sf3 321 37 . . . cord-292559-b21j9sf3 322 1 Starting start VBG cord-292559-b21j9sf3 322 2 in in IN cord-292559-b21j9sf3 322 3 year year NN cord-292559-b21j9sf3 322 4 4 4 CD cord-292559-b21j9sf3 322 5 of of IN cord-292559-b21j9sf3 322 6 data datum NNS cord-292559-b21j9sf3 322 7 collection collection NN cord-292559-b21j9sf3 322 8 , , , cord-292559-b21j9sf3 322 9 the the DT cord-292559-b21j9sf3 322 10 ABCD ABCD NNP cord-292559-b21j9sf3 322 11 Study Study NNP cord-292559-b21j9sf3 322 12 will will MD cord-292559-b21j9sf3 322 13 also also RB cord-292559-b21j9sf3 322 14 be be VB cord-292559-b21j9sf3 322 15 using use VBG cord-292559-b21j9sf3 322 16 an an DT cord-292559-b21j9sf3 322 17 app app NN cord-292559-b21j9sf3 322 18 to to TO cord-292559-b21j9sf3 322 19 assess assess VB cord-292559-b21j9sf3 322 20 phone phone NN cord-292559-b21j9sf3 322 21 and and CC cord-292559-b21j9sf3 322 22 app app NN cord-292559-b21j9sf3 322 23 usage usage NN cord-292559-b21j9sf3 322 24 with with IN cord-292559-b21j9sf3 322 25 youth youth NN cord-292559-b21j9sf3 322 26 and and CC cord-292559-b21j9sf3 322 27 parent parent NN cord-292559-b21j9sf3 322 28 permission permission NN cord-292559-b21j9sf3 322 29 . . . cord-292559-b21j9sf3 323 1 Using use VBG cord-292559-b21j9sf3 323 2 passive passive JJ cord-292559-b21j9sf3 323 3 data datum NNS cord-292559-b21j9sf3 323 4 sampling sampling NN cord-292559-b21j9sf3 323 5 , , , cord-292559-b21j9sf3 323 6 the the DT cord-292559-b21j9sf3 323 7 ABCD ABCD NNP cord-292559-b21j9sf3 323 8 Study Study NNP cord-292559-b21j9sf3 323 9 will will MD cord-292559-b21j9sf3 323 10 begin begin VB cord-292559-b21j9sf3 323 11 to to TO cord-292559-b21j9sf3 323 12 understand understand VB cord-292559-b21j9sf3 323 13 the the DT cord-292559-b21j9sf3 323 14 contributions contribution NNS cord-292559-b21j9sf3 323 15 of of IN cord-292559-b21j9sf3 323 16 physical physical JJ cord-292559-b21j9sf3 323 17 activity activity NN cord-292559-b21j9sf3 323 18 level level NN cord-292559-b21j9sf3 323 19 , , , cord-292559-b21j9sf3 323 20 sleep sleep NN cord-292559-b21j9sf3 323 21 quality quality NN cord-292559-b21j9sf3 323 22 , , , cord-292559-b21j9sf3 323 23 and and CC cord-292559-b21j9sf3 323 24 social social JJ cord-292559-b21j9sf3 323 25 media medium NNS cord-292559-b21j9sf3 323 26 use use NN cord-292559-b21j9sf3 323 27 to to IN cord-292559-b21j9sf3 323 28 the the DT cord-292559-b21j9sf3 323 29 development development NN cord-292559-b21j9sf3 323 30 and and CC cord-292559-b21j9sf3 323 31 maintenance maintenance NN cord-292559-b21j9sf3 323 32 of of IN cord-292559-b21j9sf3 323 33 negative negative JJ cord-292559-b21j9sf3 323 34 physical physical JJ cord-292559-b21j9sf3 323 35 and and CC cord-292559-b21j9sf3 323 36 mental mental JJ cord-292559-b21j9sf3 323 37 health health NN cord-292559-b21j9sf3 323 38 outcomes outcome NNS cord-292559-b21j9sf3 323 39 . . . cord-292559-b21j9sf3 324 1 Examining examine VBG cord-292559-b21j9sf3 324 2 complex complex JJ cord-292559-b21j9sf3 324 3 patterns pattern NNS cord-292559-b21j9sf3 324 4 of of IN cord-292559-b21j9sf3 324 5 interactions interaction NNS cord-292559-b21j9sf3 324 6 . . . cord-292559-b21j9sf3 325 1 Another another DT cord-292559-b21j9sf3 325 2 future future JJ cord-292559-b21j9sf3 325 3 direction direction NN cord-292559-b21j9sf3 325 4 for for IN cord-292559-b21j9sf3 325 5 ABCD ABCD NNP cord-292559-b21j9sf3 325 6 Study Study NNP cord-292559-b21j9sf3 325 7 data data NN cord-292559-b21j9sf3 325 8 is be VBZ cord-292559-b21j9sf3 325 9 examining examine VBG cord-292559-b21j9sf3 325 10 complex complex JJ cord-292559-b21j9sf3 325 11 interactions interaction NNS cord-292559-b21j9sf3 325 12 . . . cord-292559-b21j9sf3 326 1 These these DT cord-292559-b21j9sf3 326 2 examinations examination NNS cord-292559-b21j9sf3 326 3 will will MD cord-292559-b21j9sf3 326 4 likely likely RB cord-292559-b21j9sf3 326 5 take take VB cord-292559-b21j9sf3 326 6 several several JJ cord-292559-b21j9sf3 326 7 forms form NNS cord-292559-b21j9sf3 326 8 , , , cord-292559-b21j9sf3 326 9 so so IN cord-292559-b21j9sf3 326 10 the the DT cord-292559-b21j9sf3 326 11 current current JJ cord-292559-b21j9sf3 326 12 review review NN cord-292559-b21j9sf3 326 13 will will MD cord-292559-b21j9sf3 326 14 focus focus VB cord-292559-b21j9sf3 326 15 on on IN cord-292559-b21j9sf3 326 16 two two CD cord-292559-b21j9sf3 326 17 : : : cord-292559-b21j9sf3 326 18 modeling model VBG cord-292559-b21j9sf3 326 19 moderating moderate VBG cord-292559-b21j9sf3 326 20 influences influence NNS cord-292559-b21j9sf3 326 21 and and CC cord-292559-b21j9sf3 326 22 examining examine VBG cord-292559-b21j9sf3 326 23 gene gene NN cord-292559-b21j9sf3 326 24 × × NN cord-292559-b21j9sf3 326 25 environment environment NN cord-292559-b21j9sf3 326 26 interactions interaction NNS cord-292559-b21j9sf3 326 27 . . . cord-292559-b21j9sf3 327 1 For for IN cord-292559-b21j9sf3 327 2 the the DT cord-292559-b21j9sf3 327 3 first first JJ cord-292559-b21j9sf3 327 4 example example NN cord-292559-b21j9sf3 327 5 of of IN cord-292559-b21j9sf3 327 6 complex complex JJ cord-292559-b21j9sf3 327 7 interactions interaction NNS cord-292559-b21j9sf3 327 8 , , , cord-292559-b21j9sf3 327 9 researchers researcher NNS cord-292559-b21j9sf3 327 10 will will MD cord-292559-b21j9sf3 327 11 be be VB cord-292559-b21j9sf3 327 12 able able JJ cord-292559-b21j9sf3 327 13 to to TO cord-292559-b21j9sf3 327 14 examine examine VB cord-292559-b21j9sf3 327 15 the the DT cord-292559-b21j9sf3 327 16 moderating moderate VBG cord-292559-b21j9sf3 327 17 influences influence NNS cord-292559-b21j9sf3 327 18 of of IN cord-292559-b21j9sf3 327 19 a a DT cord-292559-b21j9sf3 327 20 multitude multitude NN cord-292559-b21j9sf3 327 21 of of IN cord-292559-b21j9sf3 327 22 factors factor NNS cord-292559-b21j9sf3 327 23 including include VBG cord-292559-b21j9sf3 327 24 mental mental JJ cord-292559-b21j9sf3 327 25 health health NN cord-292559-b21j9sf3 327 26 ( ( -LRB- cord-292559-b21j9sf3 327 27 e.g. e.g. RB cord-292559-b21j9sf3 327 28 , , , cord-292559-b21j9sf3 327 29 internalizing internalize VBG cord-292559-b21j9sf3 327 30 and and CC cord-292559-b21j9sf3 327 31 externalizing externalize VBG cord-292559-b21j9sf3 327 32 symptoms symptom NNS cord-292559-b21j9sf3 327 33 [ [ -LRB- cord-292559-b21j9sf3 327 34 102 102 CD cord-292559-b21j9sf3 327 35 ] ] -RRB- cord-292559-b21j9sf3 327 36 ) ) -RRB- cord-292559-b21j9sf3 327 37 ; ; : cord-292559-b21j9sf3 327 38 and and CC cord-292559-b21j9sf3 327 39 psychosocial psychosocial JJ cord-292559-b21j9sf3 327 40 ( ( -LRB- cord-292559-b21j9sf3 327 41 e.g. e.g. RB cord-292559-b21j9sf3 327 42 , , , cord-292559-b21j9sf3 327 43 parental parental JJ cord-292559-b21j9sf3 327 44 influences influence NNS cord-292559-b21j9sf3 327 45 , , , cord-292559-b21j9sf3 327 46 social social JJ cord-292559-b21j9sf3 327 47 support support NN cord-292559-b21j9sf3 327 48 ) ) -RRB- cord-292559-b21j9sf3 327 49 factors factor NNS cord-292559-b21j9sf3 327 50 on on IN cord-292559-b21j9sf3 327 51 the the DT cord-292559-b21j9sf3 327 52 initiation initiation NN cord-292559-b21j9sf3 327 53 of of IN cord-292559-b21j9sf3 327 54 substance substance NN cord-292559-b21j9sf3 327 55 abuse abuse NN cord-292559-b21j9sf3 327 56 . . . cord-292559-b21j9sf3 328 1 Further further RB cord-292559-b21j9sf3 328 2 , , , cord-292559-b21j9sf3 328 3 questions question NNS cord-292559-b21j9sf3 328 4 remain remain VBP cord-292559-b21j9sf3 328 5 about about IN cord-292559-b21j9sf3 328 6 how how WRB cord-292559-b21j9sf3 328 7 different different JJ cord-292559-b21j9sf3 328 8 types type NNS cord-292559-b21j9sf3 328 9 of of IN cord-292559-b21j9sf3 328 10 substance substance NN cord-292559-b21j9sf3 328 11 use use NN cord-292559-b21j9sf3 328 12 , , , cord-292559-b21j9sf3 328 13 such such JJ cord-292559-b21j9sf3 328 14 as as IN cord-292559-b21j9sf3 328 15 drugs drug NNS cord-292559-b21j9sf3 328 16 , , , cord-292559-b21j9sf3 328 17 alcohol alcohol NN cord-292559-b21j9sf3 328 18 , , , cord-292559-b21j9sf3 328 19 and and CC cord-292559-b21j9sf3 328 20 nicotine nicotine NN cord-292559-b21j9sf3 328 21 use use NN cord-292559-b21j9sf3 328 22 interact interact VBP cord-292559-b21j9sf3 328 23 , , , cord-292559-b21j9sf3 328 24 including include VBG cord-292559-b21j9sf3 328 25 their -PRON- PRP$ cord-292559-b21j9sf3 328 26 interactive interactive JJ cord-292559-b21j9sf3 328 27 effects effect NNS cord-292559-b21j9sf3 328 28 on on IN cord-292559-b21j9sf3 328 29 cognition cognition NN cord-292559-b21j9sf3 328 30 and and CC cord-292559-b21j9sf3 328 31 neurobiology neurobiology NN cord-292559-b21j9sf3 328 32 [ [ -LRB- cord-292559-b21j9sf3 328 33 3 3 CD cord-292559-b21j9sf3 328 34 ] ] -RRB- cord-292559-b21j9sf3 328 35 . . . cord-292559-b21j9sf3 329 1 Research research NN cord-292559-b21j9sf3 329 2 using use VBG cord-292559-b21j9sf3 329 3 the the DT cord-292559-b21j9sf3 329 4 ABCD ABCD NNP cord-292559-b21j9sf3 329 5 Study Study NNP cord-292559-b21j9sf3 329 6 will will MD cord-292559-b21j9sf3 329 7 also also RB cord-292559-b21j9sf3 329 8 be be VB cord-292559-b21j9sf3 329 9 able able JJ cord-292559-b21j9sf3 329 10 to to TO cord-292559-b21j9sf3 329 11 examine examine VB cord-292559-b21j9sf3 329 12 how how WRB cord-292559-b21j9sf3 329 13 patterns pattern NNS cord-292559-b21j9sf3 329 14 of of IN cord-292559-b21j9sf3 329 15 use use NN cord-292559-b21j9sf3 329 16 interact interact VBP cord-292559-b21j9sf3 329 17 with with IN cord-292559-b21j9sf3 329 18 psychopathology psychopathology NN cord-292559-b21j9sf3 329 19 and and CC cord-292559-b21j9sf3 329 20 psychosocial psychosocial JJ cord-292559-b21j9sf3 329 21 variables variable NNS cord-292559-b21j9sf3 329 22 to to TO cord-292559-b21j9sf3 329 23 predict predict VB cord-292559-b21j9sf3 329 24 trajectories trajectory NNS cord-292559-b21j9sf3 329 25 . . . cord-292559-b21j9sf3 330 1 For for IN cord-292559-b21j9sf3 330 2 example example NN cord-292559-b21j9sf3 330 3 , , , cord-292559-b21j9sf3 330 4 it -PRON- PRP cord-292559-b21j9sf3 330 5 is be VBZ cord-292559-b21j9sf3 330 6 possible possible JJ cord-292559-b21j9sf3 330 7 that that DT cord-292559-b21j9sf3 330 8 substance substance NN cord-292559-b21j9sf3 330 9 use use NN cord-292559-b21j9sf3 330 10 interacts interact VBZ cord-292559-b21j9sf3 330 11 with with IN cord-292559-b21j9sf3 330 12 poor poor JJ cord-292559-b21j9sf3 330 13 social social JJ cord-292559-b21j9sf3 330 14 support support NN cord-292559-b21j9sf3 330 15 to to TO cord-292559-b21j9sf3 330 16 predict predict VB cord-292559-b21j9sf3 330 17 impairments impairment NNS cord-292559-b21j9sf3 330 18 in in IN cord-292559-b21j9sf3 330 19 social social JJ cord-292559-b21j9sf3 330 20 and and CC cord-292559-b21j9sf3 330 21 occupational occupational JJ cord-292559-b21j9sf3 330 22 functioning function VBG cord-292559-b21j9sf3 330 23 [ [ -LRB- cord-292559-b21j9sf3 330 24 103 103 CD cord-292559-b21j9sf3 330 25 ] ] -RRB- cord-292559-b21j9sf3 330 26 . . . cord-292559-b21j9sf3 331 1 The the DT cord-292559-b21j9sf3 331 2 ABCD ABCD NNP cord-292559-b21j9sf3 331 3 Study Study NNP cord-292559-b21j9sf3 331 4 sets set VBZ cord-292559-b21j9sf3 331 5 to to TO cord-292559-b21j9sf3 331 6 stage stage VB cord-292559-b21j9sf3 331 7 the the DT cord-292559-b21j9sf3 331 8 begin begin NN cord-292559-b21j9sf3 331 9 to to TO cord-292559-b21j9sf3 331 10 uncover uncover VB cord-292559-b21j9sf3 331 11 the the DT cord-292559-b21j9sf3 331 12 complex complex JJ cord-292559-b21j9sf3 331 13 patterns pattern NNS cord-292559-b21j9sf3 331 14 of of IN cord-292559-b21j9sf3 331 15 interactions interaction NNS cord-292559-b21j9sf3 331 16 among among IN cord-292559-b21j9sf3 331 17 psychopathology psychopathology NN cord-292559-b21j9sf3 331 18 , , , cord-292559-b21j9sf3 331 19 psychosocial psychosocial JJ cord-292559-b21j9sf3 331 20 factors factor NNS cord-292559-b21j9sf3 331 21 , , , cord-292559-b21j9sf3 331 22 and and CC cord-292559-b21j9sf3 331 23 neurobiology neurobiology NN cord-292559-b21j9sf3 331 24 , , , cord-292559-b21j9sf3 331 25 as as RB cord-292559-b21j9sf3 331 26 well well RB cord-292559-b21j9sf3 331 27 as as IN cord-292559-b21j9sf3 331 28 their -PRON- PRP$ cord-292559-b21j9sf3 331 29 interactive interactive JJ cord-292559-b21j9sf3 331 30 effects effect NNS cord-292559-b21j9sf3 331 31 on on IN cord-292559-b21j9sf3 331 32 long long JJ cord-292559-b21j9sf3 331 33 - - HYPH cord-292559-b21j9sf3 331 34 range range NN cord-292559-b21j9sf3 331 35 outcomes outcome NNS cord-292559-b21j9sf3 331 36 . . . cord-292559-b21j9sf3 332 1 Further further RB cord-292559-b21j9sf3 332 2 , , , cord-292559-b21j9sf3 332 3 the the DT cord-292559-b21j9sf3 332 4 ABCD ABCD NNP cord-292559-b21j9sf3 332 5 Study Study NNP cord-292559-b21j9sf3 332 6 has have VBZ cord-292559-b21j9sf3 332 7 oversampled oversample VBN cord-292559-b21j9sf3 332 8 for for IN cord-292559-b21j9sf3 332 9 twins twin NNS cord-292559-b21j9sf3 332 10 ( ( -LRB- cord-292559-b21j9sf3 332 11 i.e. i.e. FW cord-292559-b21j9sf3 332 12 , , , cord-292559-b21j9sf3 332 13 the the DT cord-292559-b21j9sf3 332 14 study study NN cord-292559-b21j9sf3 332 15 has have VBZ cord-292559-b21j9sf3 332 16 approximately approximately RB cord-292559-b21j9sf3 332 17 860 860 CD cord-292559-b21j9sf3 332 18 twin twin JJ cord-292559-b21j9sf3 332 19 pairs pair NNS cord-292559-b21j9sf3 332 20 at at IN cord-292559-b21j9sf3 332 21 baseline baseline NN cord-292559-b21j9sf3 332 22 ) ) -RRB- cord-292559-b21j9sf3 332 23 . . . cord-292559-b21j9sf3 333 1 This this DT cord-292559-b21j9sf3 333 2 will will MD cord-292559-b21j9sf3 333 3 allow allow VB cord-292559-b21j9sf3 333 4 researchers researcher NNS cord-292559-b21j9sf3 333 5 to to TO cord-292559-b21j9sf3 333 6 leverage leverage VB cord-292559-b21j9sf3 333 7 this this DT cord-292559-b21j9sf3 333 8 data datum NNS cord-292559-b21j9sf3 333 9 to to TO cord-292559-b21j9sf3 333 10 examine examine VB cord-292559-b21j9sf3 333 11 gene gene NN cord-292559-b21j9sf3 333 12 × × NN cord-292559-b21j9sf3 333 13 environmental environmental JJ cord-292559-b21j9sf3 333 14 interactions interaction NNS cord-292559-b21j9sf3 333 15 . . . cord-292559-b21j9sf3 334 1 Briefly briefly RB cord-292559-b21j9sf3 334 2 , , , cord-292559-b21j9sf3 334 3 bivariate bivariate JJ cord-292559-b21j9sf3 334 4 twin twin JJ cord-292559-b21j9sf3 334 5 models model NNS cord-292559-b21j9sf3 334 6 can can MD cord-292559-b21j9sf3 334 7 be be VB cord-292559-b21j9sf3 334 8 used use VBN cord-292559-b21j9sf3 334 9 in in IN cord-292559-b21j9sf3 334 10 order order NN cord-292559-b21j9sf3 334 11 to to TO cord-292559-b21j9sf3 334 12 examine examine VB cord-292559-b21j9sf3 334 13 gene gene NN cord-292559-b21j9sf3 334 14 × × NN cord-292559-b21j9sf3 334 15 environment environment NN cord-292559-b21j9sf3 334 16 interactions interaction NNS cord-292559-b21j9sf3 334 17 [ [ -LRB- cord-292559-b21j9sf3 334 18 104 104 CD cord-292559-b21j9sf3 334 19 , , , cord-292559-b21j9sf3 334 20 105 105 CD cord-292559-b21j9sf3 334 21 ] ] -RRB- cord-292559-b21j9sf3 334 22 , , , cord-292559-b21j9sf3 334 23 including include VBG cord-292559-b21j9sf3 334 24 parsing parse VBG cord-292559-b21j9sf3 334 25 out out RP cord-292559-b21j9sf3 334 26 how how WRB cord-292559-b21j9sf3 334 27 variance variance NN cord-292559-b21j9sf3 334 28 associated associate VBN cord-292559-b21j9sf3 334 29 with with IN cord-292559-b21j9sf3 334 30 additive additive NN cord-292559-b21j9sf3 334 31 genetic genetic JJ cord-292559-b21j9sf3 334 32 ( ( -LRB- cord-292559-b21j9sf3 334 33 heritable heritable JJ cord-292559-b21j9sf3 334 34 ) ) -RRB- cord-292559-b21j9sf3 334 35 and and CC cord-292559-b21j9sf3 334 36 individual individual JJ cord-292559-b21j9sf3 334 37 - - HYPH cord-292559-b21j9sf3 334 38 specific specific JJ cord-292559-b21j9sf3 334 39 environmental environmental JJ cord-292559-b21j9sf3 334 40 factors factor NNS cord-292559-b21j9sf3 334 41 contribute contribute VBP cord-292559-b21j9sf3 334 42 to to IN cord-292559-b21j9sf3 334 43 the the DT cord-292559-b21j9sf3 334 44 covariance covariance NN cord-292559-b21j9sf3 334 45 between between IN cord-292559-b21j9sf3 334 46 indices index NNS cord-292559-b21j9sf3 334 47 of of IN cord-292559-b21j9sf3 334 48 interest interest NN cord-292559-b21j9sf3 334 49 . . . cord-292559-b21j9sf3 335 1 Discordant discordant JJ cord-292559-b21j9sf3 335 2 twin twin JJ cord-292559-b21j9sf3 335 3 study study NN cord-292559-b21j9sf3 335 4 designs design NNS cord-292559-b21j9sf3 335 5 can can MD cord-292559-b21j9sf3 335 6 be be VB cord-292559-b21j9sf3 335 7 used use VBN cord-292559-b21j9sf3 335 8 to to TO cord-292559-b21j9sf3 335 9 examine examine VB cord-292559-b21j9sf3 335 10 whether whether IN cord-292559-b21j9sf3 335 11 one one CD cord-292559-b21j9sf3 335 12 twin twin NN cord-292559-b21j9sf3 335 13 who who WP cord-292559-b21j9sf3 335 14 was be VBD cord-292559-b21j9sf3 335 15 exposed expose VBN cord-292559-b21j9sf3 335 16 to to IN cord-292559-b21j9sf3 335 17 a a DT cord-292559-b21j9sf3 335 18 certain certain JJ cord-292559-b21j9sf3 335 19 environment environment NN cord-292559-b21j9sf3 335 20 ( ( -LRB- cord-292559-b21j9sf3 335 21 e.g. e.g. RB cord-292559-b21j9sf3 335 22 , , , cord-292559-b21j9sf3 335 23 an an DT cord-292559-b21j9sf3 335 24 adverse adverse JJ cord-292559-b21j9sf3 335 25 childhood childhood NN cord-292559-b21j9sf3 335 26 event event NN cord-292559-b21j9sf3 335 27 ) ) -RRB- cord-292559-b21j9sf3 335 28 has have VBZ cord-292559-b21j9sf3 335 29 a a DT cord-292559-b21j9sf3 335 30 different different JJ cord-292559-b21j9sf3 335 31 trajectory trajectory NN cord-292559-b21j9sf3 335 32 of of IN cord-292559-b21j9sf3 335 33 psychopathology psychopathology NN cord-292559-b21j9sf3 335 34 ( ( -LRB- cord-292559-b21j9sf3 335 35 e.g. e.g. RB cord-292559-b21j9sf3 335 36 , , , cord-292559-b21j9sf3 335 37 PLEs ple NNS cord-292559-b21j9sf3 335 38 ) ) -RRB- cord-292559-b21j9sf3 335 39 compared compare VBN cord-292559-b21j9sf3 335 40 to to IN cord-292559-b21j9sf3 335 41 the the DT cord-292559-b21j9sf3 335 42 twin twin NN cord-292559-b21j9sf3 335 43 who who WP cord-292559-b21j9sf3 335 44 was be VBD cord-292559-b21j9sf3 335 45 not not RB cord-292559-b21j9sf3 335 46 exposed expose VBN cord-292559-b21j9sf3 335 47 to to IN cord-292559-b21j9sf3 335 48 this this DT cord-292559-b21j9sf3 335 49 environment environment NN cord-292559-b21j9sf3 335 50 . . . cord-292559-b21j9sf3 336 1 This this DT cord-292559-b21j9sf3 336 2 would would MD cord-292559-b21j9sf3 336 3 provide provide VB cord-292559-b21j9sf3 336 4 evidence evidence NN cord-292559-b21j9sf3 336 5 that that IN cord-292559-b21j9sf3 336 6 in in IN cord-292559-b21j9sf3 336 7 the the DT cord-292559-b21j9sf3 336 8 context context NN cord-292559-b21j9sf3 336 9 of of IN cord-292559-b21j9sf3 336 10 certain certain JJ cord-292559-b21j9sf3 336 11 genetic genetic JJ cord-292559-b21j9sf3 336 12 constitutions constitution NNS cord-292559-b21j9sf3 336 13 , , , cord-292559-b21j9sf3 336 14 the the DT cord-292559-b21j9sf3 336 15 exposure exposure NN cord-292559-b21j9sf3 336 16 to to IN cord-292559-b21j9sf3 336 17 negative negative JJ cord-292559-b21j9sf3 336 18 environments environment NNS cord-292559-b21j9sf3 336 19 may may MD cord-292559-b21j9sf3 336 20 alter alter VB cord-292559-b21j9sf3 336 21 one one PRP cord-292559-b21j9sf3 336 22 's 's POS cord-292559-b21j9sf3 336 23 trajectory trajectory NN cord-292559-b21j9sf3 336 24 . . . cord-292559-b21j9sf3 337 1 Further further RB cord-292559-b21j9sf3 337 2 , , , cord-292559-b21j9sf3 337 3 researchers researcher NNS cord-292559-b21j9sf3 337 4 will will MD cord-292559-b21j9sf3 337 5 be be VB cord-292559-b21j9sf3 337 6 able able JJ cord-292559-b21j9sf3 337 7 to to TO cord-292559-b21j9sf3 337 8 examine examine VB cord-292559-b21j9sf3 337 9 polygenic polygenic JJ cord-292559-b21j9sf3 337 10 risk risk NN cord-292559-b21j9sf3 337 11 scores score NNS cord-292559-b21j9sf3 337 12 , , , cord-292559-b21j9sf3 337 13 scores score NNS cord-292559-b21j9sf3 337 14 created create VBN cord-292559-b21j9sf3 337 15 to to TO cord-292559-b21j9sf3 337 16 reflect reflect VB cord-292559-b21j9sf3 337 17 the the DT cord-292559-b21j9sf3 337 18 weighted weighted JJ cord-292559-b21j9sf3 337 19 effect effect NN cord-292559-b21j9sf3 337 20 of of IN cord-292559-b21j9sf3 337 21 individual individual JJ cord-292559-b21j9sf3 337 22 single single JJ cord-292559-b21j9sf3 337 23 nucleotide nucleotide JJ cord-292559-b21j9sf3 337 24 polymorphisms polymorphism NNS cord-292559-b21j9sf3 337 25 associated associate VBN cord-292559-b21j9sf3 337 26 with with IN cord-292559-b21j9sf3 337 27 risk risk NN cord-292559-b21j9sf3 337 28 for for IN cord-292559-b21j9sf3 337 29 an an DT cord-292559-b21j9sf3 337 30 outcome outcome NN cord-292559-b21j9sf3 337 31 , , , cord-292559-b21j9sf3 337 32 to to TO cord-292559-b21j9sf3 337 33 examine examine VB cord-292559-b21j9sf3 337 34 how how WRB cord-292559-b21j9sf3 337 35 heightened heighten VBN cord-292559-b21j9sf3 337 36 the the DT cord-292559-b21j9sf3 337 37 genetic genetic JJ cord-292559-b21j9sf3 337 38 risk risk NN cord-292559-b21j9sf3 337 39 for for IN cord-292559-b21j9sf3 337 40 disorders disorder NNS cord-292559-b21j9sf3 337 41 interacts interact VBZ cord-292559-b21j9sf3 337 42 with with IN cord-292559-b21j9sf3 337 43 environmental environmental JJ cord-292559-b21j9sf3 337 44 factors factor NNS cord-292559-b21j9sf3 337 45 to to TO cord-292559-b21j9sf3 337 46 predict predict VB cord-292559-b21j9sf3 337 47 development development NN cord-292559-b21j9sf3 337 48 of of IN cord-292559-b21j9sf3 337 49 disorders disorder NNS cord-292559-b21j9sf3 337 50 [ [ -LRB- cord-292559-b21j9sf3 337 51 106 106 CD cord-292559-b21j9sf3 337 52 ] ] -RRB- cord-292559-b21j9sf3 337 53 . . . cord-292559-b21j9sf3 338 1 For for IN cord-292559-b21j9sf3 338 2 example example NN cord-292559-b21j9sf3 338 3 , , , cord-292559-b21j9sf3 338 4 researchers researcher NNS cord-292559-b21j9sf3 338 5 will will MD cord-292559-b21j9sf3 338 6 be be VB cord-292559-b21j9sf3 338 7 able able JJ cord-292559-b21j9sf3 338 8 to to TO cord-292559-b21j9sf3 338 9 examine examine VB cord-292559-b21j9sf3 338 10 how how WRB cord-292559-b21j9sf3 338 11 schizophrenia schizophrenia NNP cord-292559-b21j9sf3 338 12 polygenic polygenic JJ cord-292559-b21j9sf3 338 13 risk risk NN cord-292559-b21j9sf3 338 14 interacts interact VBZ cord-292559-b21j9sf3 338 15 with with IN cord-292559-b21j9sf3 338 16 factors factor NNS cord-292559-b21j9sf3 338 17 such such JJ cord-292559-b21j9sf3 338 18 as as IN cord-292559-b21j9sf3 338 19 cannabis cannabis NN cord-292559-b21j9sf3 338 20 use use NN cord-292559-b21j9sf3 338 21 to to TO cord-292559-b21j9sf3 338 22 predict predict VB cord-292559-b21j9sf3 338 23 the the DT cord-292559-b21j9sf3 338 24 development development NN cord-292559-b21j9sf3 338 25 of of IN cord-292559-b21j9sf3 338 26 schizophrenia schizophrenia NNP cord-292559-b21j9sf3 338 27 spectrum spectrum NN cord-292559-b21j9sf3 338 28 symptoms symptom NNS cord-292559-b21j9sf3 338 29 . . . cord-292559-b21j9sf3 339 1 Thus thus RB cord-292559-b21j9sf3 339 2 , , , cord-292559-b21j9sf3 339 3 researchers researcher NNS cord-292559-b21j9sf3 339 4 can can MD cord-292559-b21j9sf3 339 5 use use VB cord-292559-b21j9sf3 339 6 the the DT cord-292559-b21j9sf3 339 7 ABCD ABCD NNP cord-292559-b21j9sf3 339 8 Study Study NNP cord-292559-b21j9sf3 339 9 to to TO cord-292559-b21j9sf3 339 10 begin begin VB cord-292559-b21j9sf3 339 11 to to TO cord-292559-b21j9sf3 339 12 tease tease VB cord-292559-b21j9sf3 339 13 apart apart RB cord-292559-b21j9sf3 339 14 complex complex JJ cord-292559-b21j9sf3 339 15 genetic genetic JJ cord-292559-b21j9sf3 339 16 versus versus IN cord-292559-b21j9sf3 339 17 environmental environmental JJ cord-292559-b21j9sf3 339 18 contributions contribution NNS cord-292559-b21j9sf3 339 19 to to IN cord-292559-b21j9sf3 339 20 psychopathology psychopathology NN cord-292559-b21j9sf3 339 21 . . . cord-292559-b21j9sf3 340 1 The the DT cord-292559-b21j9sf3 340 2 current current JJ cord-292559-b21j9sf3 340 3 review review NN cord-292559-b21j9sf3 340 4 provided provide VBD cord-292559-b21j9sf3 340 5 an an DT cord-292559-b21j9sf3 340 6 overview overview NN cord-292559-b21j9sf3 340 7 of of IN cord-292559-b21j9sf3 340 8 the the DT cord-292559-b21j9sf3 340 9 goals goal NNS cord-292559-b21j9sf3 340 10 , , , cord-292559-b21j9sf3 340 11 methods method NNS cord-292559-b21j9sf3 340 12 , , , cord-292559-b21j9sf3 340 13 initial initial JJ cord-292559-b21j9sf3 340 14 results result NNS cord-292559-b21j9sf3 340 15 , , , cord-292559-b21j9sf3 340 16 and and CC cord-292559-b21j9sf3 340 17 future future JJ cord-292559-b21j9sf3 340 18 directions direction NNS cord-292559-b21j9sf3 340 19 for for IN cord-292559-b21j9sf3 340 20 the the DT cord-292559-b21j9sf3 340 21 ABCD ABCD NNP cord-292559-b21j9sf3 340 22 Study Study NNP cord-292559-b21j9sf3 340 23 for for IN cord-292559-b21j9sf3 340 24 understanding understand VBG cord-292559-b21j9sf3 340 25 the the DT cord-292559-b21j9sf3 340 26 development development NN cord-292559-b21j9sf3 340 27 of of IN cord-292559-b21j9sf3 340 28 risk risk NN cord-292559-b21j9sf3 340 29 . . . cord-292559-b21j9sf3 341 1 The the DT cord-292559-b21j9sf3 341 2 ABCD ABCD NNP cord-292559-b21j9sf3 341 3 Study Study NNP cord-292559-b21j9sf3 341 4 is be VBZ cord-292559-b21j9sf3 341 5 a a DT cord-292559-b21j9sf3 341 6 historic historic JJ cord-292559-b21j9sf3 341 7 study study NN cord-292559-b21j9sf3 341 8 following follow VBG cord-292559-b21j9sf3 341 9 youth youth NN cord-292559-b21j9sf3 341 10 from from IN cord-292559-b21j9sf3 341 11 ages age NNS cord-292559-b21j9sf3 341 12 9 9 CD cord-292559-b21j9sf3 341 13 into into IN cord-292559-b21j9sf3 341 14 early early JJ cord-292559-b21j9sf3 341 15 adulthood adulthood NN cord-292559-b21j9sf3 341 16 and and CC cord-292559-b21j9sf3 341 17 is be VBZ cord-292559-b21j9sf3 341 18 currently currently RB cord-292559-b21j9sf3 341 19 in in IN cord-292559-b21j9sf3 341 20 its -PRON- PRP$ cord-292559-b21j9sf3 341 21 fourth fourth JJ cord-292559-b21j9sf3 341 22 year year NN cord-292559-b21j9sf3 341 23 of of IN cord-292559-b21j9sf3 341 24 data datum NNS cord-292559-b21j9sf3 341 25 collection collection NN cord-292559-b21j9sf3 341 26 . . . cord-292559-b21j9sf3 342 1 The the DT cord-292559-b21j9sf3 342 2 study study NN cord-292559-b21j9sf3 342 3 operates operate VBZ cord-292559-b21j9sf3 342 4 under under IN cord-292559-b21j9sf3 342 5 an an DT cord-292559-b21j9sf3 342 6 open open JJ cord-292559-b21j9sf3 342 7 science science NN cord-292559-b21j9sf3 342 8 framework framework NN cord-292559-b21j9sf3 342 9 and and CC cord-292559-b21j9sf3 342 10 therefore therefore RB cord-292559-b21j9sf3 342 11 annually annually RB cord-292559-b21j9sf3 342 12 releases release VBZ cord-292559-b21j9sf3 342 13 data datum NNS cord-292559-b21j9sf3 342 14 to to IN cord-292559-b21j9sf3 342 15 the the DT cord-292559-b21j9sf3 342 16 public public NN cord-292559-b21j9sf3 342 17 . . . cord-292559-b21j9sf3 343 1 It -PRON- PRP cord-292559-b21j9sf3 343 2 is be VBZ cord-292559-b21j9sf3 343 3 a a DT cord-292559-b21j9sf3 343 4 large large JJ cord-292559-b21j9sf3 343 5 - - HYPH cord-292559-b21j9sf3 343 6 scale scale NN cord-292559-b21j9sf3 343 7 population population NN cord-292559-b21j9sf3 343 8 neuroscience neuroscience NN cord-292559-b21j9sf3 343 9 study study NN cord-292559-b21j9sf3 343 10 examining examine VBG cord-292559-b21j9sf3 343 11 a a DT cord-292559-b21j9sf3 343 12 heterogenous heterogenous JJ cord-292559-b21j9sf3 343 13 population population NN cord-292559-b21j9sf3 343 14 recruited recruit VBN cord-292559-b21j9sf3 343 15 to to TO cord-292559-b21j9sf3 343 16 reflect reflect VB cord-292559-b21j9sf3 343 17 U.S. U.S. NNP cord-292559-b21j9sf3 343 18 national national JJ cord-292559-b21j9sf3 343 19 sociodemographic sociodemographic JJ cord-292559-b21j9sf3 343 20 proportions proportion NNS cord-292559-b21j9sf3 343 21 . . . cord-292559-b21j9sf3 344 1 The the DT cord-292559-b21j9sf3 344 2 study study NN cord-292559-b21j9sf3 344 3 is be VBZ cord-292559-b21j9sf3 344 4 collecting collect VBG cord-292559-b21j9sf3 344 5 data datum NNS cord-292559-b21j9sf3 344 6 across across IN cord-292559-b21j9sf3 344 7 a a DT cord-292559-b21j9sf3 344 8 spectrum spectrum NN cord-292559-b21j9sf3 344 9 of of IN cord-292559-b21j9sf3 344 10 domains domain NNS cord-292559-b21j9sf3 344 11 , , , cord-292559-b21j9sf3 344 12 including include VBG cord-292559-b21j9sf3 344 13 mental mental JJ cord-292559-b21j9sf3 344 14 and and CC cord-292559-b21j9sf3 344 15 physical physical JJ cord-292559-b21j9sf3 344 16 health health NN cord-292559-b21j9sf3 344 17 , , , cord-292559-b21j9sf3 344 18 culture culture NN cord-292559-b21j9sf3 344 19 and and CC cord-292559-b21j9sf3 344 20 environment environment NN cord-292559-b21j9sf3 344 21 , , , cord-292559-b21j9sf3 344 22 biospecimens biospecimen NNS cord-292559-b21j9sf3 344 23 , , , cord-292559-b21j9sf3 344 24 and and CC cord-292559-b21j9sf3 344 25 neuroimaging neuroimaging NN cord-292559-b21j9sf3 344 26 . . . cord-292559-b21j9sf3 345 1 Emerging emerge VBG cord-292559-b21j9sf3 345 2 cross cross JJ cord-292559-b21j9sf3 345 3 - - JJ cord-292559-b21j9sf3 345 4 sectional sectional JJ cord-292559-b21j9sf3 345 5 results result NNS cord-292559-b21j9sf3 345 6 published publish VBN cord-292559-b21j9sf3 345 7 from from IN cord-292559-b21j9sf3 345 8 this this DT cord-292559-b21j9sf3 345 9 study study NN cord-292559-b21j9sf3 345 10 have have VBP cord-292559-b21j9sf3 345 11 already already RB cord-292559-b21j9sf3 345 12 contributed contribute VBN cord-292559-b21j9sf3 345 13 to to IN cord-292559-b21j9sf3 345 14 novel novel JJ cord-292559-b21j9sf3 345 15 insights insight NNS cord-292559-b21j9sf3 345 16 regarding regard VBG cord-292559-b21j9sf3 345 17 psychopathology psychopathology NN cord-292559-b21j9sf3 345 18 and and CC cord-292559-b21j9sf3 345 19 brain brain NN cord-292559-b21j9sf3 345 20 and and CC cord-292559-b21j9sf3 345 21 behavior behavior NN cord-292559-b21j9sf3 345 22 correlates correlate VBZ cord-292559-b21j9sf3 345 23 in in IN cord-292559-b21j9sf3 345 24 middle middle JJ cord-292559-b21j9sf3 345 25 childhood childhood NN cord-292559-b21j9sf3 345 26 . . . cord-292559-b21j9sf3 346 1 The the DT cord-292559-b21j9sf3 346 2 ABCD ABCD NNP cord-292559-b21j9sf3 346 3 Study Study NNP cord-292559-b21j9sf3 346 4 aims aim VBZ cord-292559-b21j9sf3 346 5 to to TO cord-292559-b21j9sf3 346 6 better well RBR cord-292559-b21j9sf3 346 7 understand understand VB cord-292559-b21j9sf3 346 8 both both CC cord-292559-b21j9sf3 346 9 normative normative JJ cord-292559-b21j9sf3 346 10 and and CC cord-292559-b21j9sf3 346 11 non non JJ cord-292559-b21j9sf3 346 12 - - JJ cord-292559-b21j9sf3 346 13 normative normative JJ cord-292559-b21j9sf3 346 14 trajectories trajectory NNS cord-292559-b21j9sf3 346 15 of of IN cord-292559-b21j9sf3 346 16 development development NN cord-292559-b21j9sf3 346 17 , , , cord-292559-b21j9sf3 346 18 examining examine VBG cord-292559-b21j9sf3 346 19 risk risk NN cord-292559-b21j9sf3 346 20 for for IN cord-292559-b21j9sf3 346 21 the the DT cord-292559-b21j9sf3 346 22 development development NN cord-292559-b21j9sf3 346 23 of of IN cord-292559-b21j9sf3 346 24 many many JJ cord-292559-b21j9sf3 346 25 mental mental JJ cord-292559-b21j9sf3 346 26 and and CC cord-292559-b21j9sf3 346 27 physical physical JJ cord-292559-b21j9sf3 346 28 health health NN cord-292559-b21j9sf3 346 29 outcomes outcome NNS cord-292559-b21j9sf3 346 30 , , , cord-292559-b21j9sf3 346 31 including include VBG cord-292559-b21j9sf3 346 32 substance substance NN cord-292559-b21j9sf3 346 33 use use NN cord-292559-b21j9sf3 346 34 . . . cord-292559-b21j9sf3 347 1 The the DT cord-292559-b21j9sf3 347 2 characteristics characteristic NNS cord-292559-b21j9sf3 347 3 of of IN cord-292559-b21j9sf3 347 4 the the DT cord-292559-b21j9sf3 347 5 ABCD ABCD NNP cord-292559-b21j9sf3 347 6 Study Study NNP cord-292559-b21j9sf3 347 7 , , , cord-292559-b21j9sf3 347 8 including include VBG cord-292559-b21j9sf3 347 9 a a DT cord-292559-b21j9sf3 347 10 large large JJ cord-292559-b21j9sf3 347 11 heterogeneous heterogeneous JJ cord-292559-b21j9sf3 347 12 sample sample NN cord-292559-b21j9sf3 347 13 longitudinally longitudinally RB cord-292559-b21j9sf3 347 14 following follow VBG cord-292559-b21j9sf3 347 15 youth youth NN cord-292559-b21j9sf3 347 16 across across IN cord-292559-b21j9sf3 347 17 development development NN cord-292559-b21j9sf3 347 18 , , , cord-292559-b21j9sf3 347 19 pose pose VBP cord-292559-b21j9sf3 347 20 unique unique JJ cord-292559-b21j9sf3 347 21 opportunities opportunity NNS cord-292559-b21j9sf3 347 22 for for IN cord-292559-b21j9sf3 347 23 understanding understand VBG cord-292559-b21j9sf3 347 24 the the DT cord-292559-b21j9sf3 347 25 development development NN cord-292559-b21j9sf3 347 26 of of IN cord-292559-b21j9sf3 347 27 risk risk NN cord-292559-b21j9sf3 347 28 . . . cord-292559-b21j9sf3 348 1 The the DT cord-292559-b21j9sf3 348 2 heterogenous heterogenous JJ cord-292559-b21j9sf3 348 3 sample sample NN cord-292559-b21j9sf3 348 4 combined combine VBN cord-292559-b21j9sf3 348 5 with with IN cord-292559-b21j9sf3 348 6 examining examine VBG cord-292559-b21j9sf3 348 7 a a DT cord-292559-b21j9sf3 348 8 middle middle JJ cord-292559-b21j9sf3 348 9 childhood childhood NN cord-292559-b21j9sf3 348 10 sample sample NN cord-292559-b21j9sf3 348 11 , , , cord-292559-b21j9sf3 348 12 years year NNS cord-292559-b21j9sf3 348 13 prior prior RB cord-292559-b21j9sf3 348 14 to to IN cord-292559-b21j9sf3 348 15 the the DT cord-292559-b21j9sf3 348 16 period period NN cord-292559-b21j9sf3 348 17 of of IN cord-292559-b21j9sf3 348 18 greatest great JJS cord-292559-b21j9sf3 348 19 risk risk NN cord-292559-b21j9sf3 348 20 for for IN cord-292559-b21j9sf3 348 21 many many JJ cord-292559-b21j9sf3 348 22 disorders disorder NNS cord-292559-b21j9sf3 348 23 , , , cord-292559-b21j9sf3 348 24 often often RB cord-292559-b21j9sf3 348 25 results result VBZ cord-292559-b21j9sf3 348 26 in in IN cord-292559-b21j9sf3 348 27 finding find VBG cord-292559-b21j9sf3 348 28 smallmoderate smallmoderate JJ cord-292559-b21j9sf3 348 29 effects effect NNS cord-292559-b21j9sf3 348 30 . . . cord-292559-b21j9sf3 349 1 Further further RB cord-292559-b21j9sf3 349 2 , , , cord-292559-b21j9sf3 349 3 researchers researcher NNS cord-292559-b21j9sf3 349 4 have have VBP cord-292559-b21j9sf3 349 5 the the DT cord-292559-b21j9sf3 349 6 opportunity opportunity NN cord-292559-b21j9sf3 349 7 to to TO cord-292559-b21j9sf3 349 8 conduct conduct VB cord-292559-b21j9sf3 349 9 exploratory exploratory JJ cord-292559-b21j9sf3 349 10 analyses analysis NNS cord-292559-b21j9sf3 349 11 that that WDT cord-292559-b21j9sf3 349 12 incorporate incorporate VBP cord-292559-b21j9sf3 349 13 rigorous rigorous JJ cord-292559-b21j9sf3 349 14 best good JJS cord-292559-b21j9sf3 349 15 practices practice NNS cord-292559-b21j9sf3 349 16 for for IN cord-292559-b21j9sf3 349 17 data data NN cord-292559-b21j9sf3 349 18 analysis analysis NN cord-292559-b21j9sf3 349 19 including include VBG cord-292559-b21j9sf3 349 20 conducting conduct VBG cord-292559-b21j9sf3 349 21 power power NN cord-292559-b21j9sf3 349 22 analyses analysis NNS cord-292559-b21j9sf3 349 23 . . . cord-292559-b21j9sf3 350 1 It -PRON- PRP cord-292559-b21j9sf3 350 2 will will MD cord-292559-b21j9sf3 350 3 be be VB cord-292559-b21j9sf3 350 4 crucial crucial JJ cord-292559-b21j9sf3 350 5 for for IN cord-292559-b21j9sf3 350 6 researchers researcher NNS cord-292559-b21j9sf3 350 7 to to TO cord-292559-b21j9sf3 350 8 replicate replicate VB cord-292559-b21j9sf3 350 9 findings finding NNS cord-292559-b21j9sf3 350 10 either either CC cord-292559-b21j9sf3 350 11 using use VBG cord-292559-b21j9sf3 350 12 the the DT cord-292559-b21j9sf3 350 13 ABCD ABCD NNP cord-292559-b21j9sf3 350 14 Study Study NNP cord-292559-b21j9sf3 350 15 sample sample NN cord-292559-b21j9sf3 350 16 ( ( -LRB- cord-292559-b21j9sf3 350 17 i.e. i.e. FW cord-292559-b21j9sf3 350 18 , , , cord-292559-b21j9sf3 350 19 using use VBG cord-292559-b21j9sf3 350 20 discovery discovery NN cord-292559-b21j9sf3 350 21 and and CC cord-292559-b21j9sf3 350 22 replication replication NN cord-292559-b21j9sf3 350 23 samples sample NNS cord-292559-b21j9sf3 350 24 or or CC cord-292559-b21j9sf3 350 25 using use VBG cord-292559-b21j9sf3 350 26 additional additional JJ cord-292559-b21j9sf3 350 27 data datum NNS cord-292559-b21j9sf3 350 28 collection collection NN cord-292559-b21j9sf3 350 29 waves wave NNS cord-292559-b21j9sf3 350 30 ) ) -RRB- cord-292559-b21j9sf3 350 31 or or CC cord-292559-b21j9sf3 350 32 using use VBG cord-292559-b21j9sf3 350 33 an an DT cord-292559-b21j9sf3 350 34 independent independent JJ cord-292559-b21j9sf3 350 35 sample sample NN cord-292559-b21j9sf3 350 36 ( ( -LRB- cord-292559-b21j9sf3 350 37 Table Table NNP cord-292559-b21j9sf3 350 38 2 2 CD cord-292559-b21j9sf3 350 39 ) ) -RRB- cord-292559-b21j9sf3 350 40 . . . cord-292559-b21j9sf3 351 1 As as IN cord-292559-b21j9sf3 351 2 the the DT cord-292559-b21j9sf3 351 3 ABCD ABCD NNP cord-292559-b21j9sf3 351 4 Study Study NNP cord-292559-b21j9sf3 351 5 makes make VBZ cord-292559-b21j9sf3 351 6 advances advance NNS cord-292559-b21j9sf3 351 7 in in IN cord-292559-b21j9sf3 351 8 our -PRON- PRP$ cord-292559-b21j9sf3 351 9 understanding understanding NN cord-292559-b21j9sf3 351 10 of of IN cord-292559-b21j9sf3 351 11 risk risk NN cord-292559-b21j9sf3 351 12 and and CC cord-292559-b21j9sf3 351 13 resiliency resiliency NN cord-292559-b21j9sf3 351 14 factors factor NNS cord-292559-b21j9sf3 351 15 associated associate VBN cord-292559-b21j9sf3 351 16 with with IN cord-292559-b21j9sf3 351 17 psychopathology psychopathology NN cord-292559-b21j9sf3 351 18 , , , cord-292559-b21j9sf3 351 19 it -PRON- PRP cord-292559-b21j9sf3 351 20 will will MD cord-292559-b21j9sf3 351 21 be be VB cord-292559-b21j9sf3 351 22 critical critical JJ cord-292559-b21j9sf3 351 23 for for IN cord-292559-b21j9sf3 351 24 researchers researcher NNS cord-292559-b21j9sf3 351 25 to to TO cord-292559-b21j9sf3 351 26 begin begin VB cord-292559-b21j9sf3 351 27 to to TO cord-292559-b21j9sf3 351 28 translate translate VB cord-292559-b21j9sf3 351 29 these these DT cord-292559-b21j9sf3 351 30 findings finding NNS cord-292559-b21j9sf3 351 31 into into IN cord-292559-b21j9sf3 351 32 screening screening NN cord-292559-b21j9sf3 351 33 and and CC cord-292559-b21j9sf3 351 34 intervention intervention NN cord-292559-b21j9sf3 351 35 advances advance NNS cord-292559-b21j9sf3 351 36 . . . cord-292559-b21j9sf3 352 1 This this DT cord-292559-b21j9sf3 352 2 work work NN cord-292559-b21j9sf3 352 3 was be VBD cord-292559-b21j9sf3 352 4 supported support VBN cord-292559-b21j9sf3 352 5 by by IN cord-292559-b21j9sf3 352 6 National National NNP cord-292559-b21j9sf3 352 7 Institute Institute NNP cord-292559-b21j9sf3 352 8 on on IN cord-292559-b21j9sf3 352 9 Drug Drug NNP cord-292559-b21j9sf3 352 10 Abuse Abuse NNP cord-292559-b21j9sf3 352 11 grant grant NN cord-292559-b21j9sf3 352 12 U01 U01 NNP cord-292559-b21j9sf3 352 13 DA041120 DA041120 NNP cord-292559-b21j9sf3 352 14 ( ( -LRB- cord-292559-b21j9sf3 352 15 DMB DMB NNP cord-292559-b21j9sf3 352 16 ) ) -RRB- cord-292559-b21j9sf3 352 17 and and CC cord-292559-b21j9sf3 352 18 National National NNP cord-292559-b21j9sf3 352 19 Institute Institute NNP cord-292559-b21j9sf3 352 20 of of IN cord-292559-b21j9sf3 352 21 Health Health NNP cord-292559-b21j9sf3 352 22 grants grant VBZ cord-292559-b21j9sf3 352 23 T32 T32 NNP cord-292559-b21j9sf3 352 24 MH014677 MH014677 NNP cord-292559-b21j9sf3 352 25 and and CC cord-292559-b21j9sf3 352 26 L30 L30 NNP cord-292559-b21j9sf3 352 27 MH120574 MH120574 NNP cord-292559-b21j9sf3 352 28 - - HYPH cord-292559-b21j9sf3 352 29 01 01 NNP cord-292559-b21j9sf3 352 30 ( ( -LRB- cord-292559-b21j9sf3 352 31 NRK NRK NNP cord-292559-b21j9sf3 352 32 ) ) -RRB- cord-292559-b21j9sf3 352 33 . . . cord-292559-b21j9sf3 353 1 The the DT cord-292559-b21j9sf3 353 2 authors author NNS cord-292559-b21j9sf3 353 3 declare declare VBP cord-292559-b21j9sf3 353 4 no no DT cord-292559-b21j9sf3 353 5 competing compete VBG cord-292559-b21j9sf3 353 6 interests interest NNS cord-292559-b21j9sf3 353 7 . . . cord-292559-b21j9sf3 354 1 NRK NRK NNP cord-292559-b21j9sf3 354 2 and and CC cord-292559-b21j9sf3 354 3 DMB DMB NNP cord-292559-b21j9sf3 354 4 jointly jointly RB cord-292559-b21j9sf3 354 5 developed develop VBD cord-292559-b21j9sf3 354 6 an an DT cord-292559-b21j9sf3 354 7 outline outline NN cord-292559-b21j9sf3 354 8 . . . cord-292559-b21j9sf3 355 1 NRK NRK NNP cord-292559-b21j9sf3 355 2 drafted draft VBD cord-292559-b21j9sf3 355 3 the the DT cord-292559-b21j9sf3 355 4 paper paper NN cord-292559-b21j9sf3 355 5 and and CC cord-292559-b21j9sf3 355 6 DMB DMB NNP cord-292559-b21j9sf3 355 7 provided provide VBD cord-292559-b21j9sf3 355 8 critical critical JJ cord-292559-b21j9sf3 355 9 revisions revision NNS cord-292559-b21j9sf3 355 10 and and CC cord-292559-b21j9sf3 355 11 table table NN cord-292559-b21j9sf3 355 12 information information NN cord-292559-b21j9sf3 355 13 . . . cord-292559-b21j9sf3 356 1 All all DT cord-292559-b21j9sf3 356 2 authors author NNS cord-292559-b21j9sf3 356 3 approved approve VBD cord-292559-b21j9sf3 356 4 the the DT cord-292559-b21j9sf3 356 5 final final JJ cord-292559-b21j9sf3 356 6 version version NN cord-292559-b21j9sf3 356 7 of of IN cord-292559-b21j9sf3 356 8 the the DT cord-292559-b21j9sf3 356 9 paper paper NN cord-292559-b21j9sf3 356 10 for for IN cord-292559-b21j9sf3 356 11 submission submission NN cord-292559-b21j9sf3 356 12 . . . cord-292559-b21j9sf3 357 1 Publisher publisher NN cord-292559-b21j9sf3 357 2 's 's POS cord-292559-b21j9sf3 357 3 note note NN cord-292559-b21j9sf3 357 4 Springer Springer NNP cord-292559-b21j9sf3 357 5 Nature Nature NNP cord-292559-b21j9sf3 357 6 remains remain VBZ cord-292559-b21j9sf3 357 7 neutral neutral JJ cord-292559-b21j9sf3 357 8 with with IN cord-292559-b21j9sf3 357 9 regard regard NN cord-292559-b21j9sf3 357 10 to to IN cord-292559-b21j9sf3 357 11 jurisdictional jurisdictional JJ cord-292559-b21j9sf3 357 12 claims claim NNS cord-292559-b21j9sf3 357 13 in in IN cord-292559-b21j9sf3 357 14 published publish VBN cord-292559-b21j9sf3 357 15 maps map NNS cord-292559-b21j9sf3 357 16 and and CC cord-292559-b21j9sf3 357 17 institutional institutional JJ cord-292559-b21j9sf3 357 18 affiliations affiliation NNS cord-292559-b21j9sf3 357 19 . . . cord-292559-b21j9sf3 358 1 Demographic demographic JJ cord-292559-b21j9sf3 358 2 , , , cord-292559-b21j9sf3 358 3 physical physical JJ cord-292559-b21j9sf3 358 4 and and CC cord-292559-b21j9sf3 358 5 mental mental JJ cord-292559-b21j9sf3 358 6 health health NN cord-292559-b21j9sf3 358 7 assessments assessment NNS cord-292559-b21j9sf3 358 8 in in IN cord-292559-b21j9sf3 358 9 the the DT cord-292559-b21j9sf3 358 10 adolescent adolescent JJ cord-292559-b21j9sf3 358 11 brain brain NN cord-292559-b21j9sf3 358 12 and and CC cord-292559-b21j9sf3 358 13 cognitive cognitive JJ cord-292559-b21j9sf3 358 14 development development NN cord-292559-b21j9sf3 358 15 study study NN cord-292559-b21j9sf3 358 16 : : : cord-292559-b21j9sf3 358 17 rationale rationale NN cord-292559-b21j9sf3 358 18 and and CC cord-292559-b21j9sf3 358 19 description description NN cord-292559-b21j9sf3 358 20 Adolescent adolescent JJ cord-292559-b21j9sf3 358 21 brain brain NN cord-292559-b21j9sf3 358 22 development development NN cord-292559-b21j9sf3 358 23 : : : cord-292559-b21j9sf3 358 24 implications implication NNS cord-292559-b21j9sf3 358 25 for for IN cord-292559-b21j9sf3 358 26 understanding understand VBG cord-292559-b21j9sf3 358 27 risk risk NN cord-292559-b21j9sf3 358 28 and and CC cord-292559-b21j9sf3 358 29 resilience resilience NN cord-292559-b21j9sf3 358 30 processes process NNS cord-292559-b21j9sf3 358 31 through through IN cord-292559-b21j9sf3 358 32 neuroimaging neuroimage VBG cord-292559-b21j9sf3 358 33 research research NN cord-292559-b21j9sf3 359 1 The the DT cord-292559-b21j9sf3 359 2 conception conception NN cord-292559-b21j9sf3 359 3 of of IN cord-292559-b21j9sf3 359 4 the the DT cord-292559-b21j9sf3 359 5 ABCD ABCD NNP cord-292559-b21j9sf3 359 6 study study NN cord-292559-b21j9sf3 359 7 : : : cord-292559-b21j9sf3 359 8 from from IN cord-292559-b21j9sf3 359 9 substance substance NN cord-292559-b21j9sf3 359 10 use use NN cord-292559-b21j9sf3 359 11 to to IN cord-292559-b21j9sf3 359 12 a a DT cord-292559-b21j9sf3 359 13 broad broad JJ cord-292559-b21j9sf3 359 14 NIH NIH NNP cord-292559-b21j9sf3 359 15 collaboration collaboration NN cord-292559-b21j9sf3 359 16 The the DT cord-292559-b21j9sf3 359 17 national national JJ cord-292559-b21j9sf3 359 18 consortium consortium NN cord-292559-b21j9sf3 359 19 on on IN cord-292559-b21j9sf3 359 20 alcohol alcohol NN cord-292559-b21j9sf3 359 21 and and CC cord-292559-b21j9sf3 359 22 neurodevelopment neurodevelopment JJ cord-292559-b21j9sf3 359 23 in in IN cord-292559-b21j9sf3 359 24 adolescence adolescence NN cord-292559-b21j9sf3 359 25 ( ( -LRB- cord-292559-b21j9sf3 359 26 NCANDA NCANDA NNP cord-292559-b21j9sf3 359 27 ) ) -RRB- cord-292559-b21j9sf3 359 28 : : : cord-292559-b21j9sf3 359 29 a a DT cord-292559-b21j9sf3 359 30 multisite multisite JJ cord-292559-b21j9sf3 359 31 study study NN cord-292559-b21j9sf3 359 32 of of IN cord-292559-b21j9sf3 359 33 adolescent adolescent JJ cord-292559-b21j9sf3 359 34 development development NN cord-292559-b21j9sf3 359 35 and and CC cord-292559-b21j9sf3 359 36 substance substance NN cord-292559-b21j9sf3 359 37 use use VBP cord-292559-b21j9sf3 359 38 The the DT cord-292559-b21j9sf3 359 39 Generation Generation NNP cord-292559-b21j9sf3 359 40 R r NN cord-292559-b21j9sf3 359 41 Study study NN cord-292559-b21j9sf3 359 42 : : : cord-292559-b21j9sf3 359 43 design design NN cord-292559-b21j9sf3 359 44 and and CC cord-292559-b21j9sf3 359 45 cohort cohort NN cord-292559-b21j9sf3 360 1 update update NN cord-292559-b21j9sf3 360 2 2017 2017 CD cord-292559-b21j9sf3 361 1 The the DT cord-292559-b21j9sf3 361 2 IMAGEN IMAGEN NNP cord-292559-b21j9sf3 361 3 study study NN cord-292559-b21j9sf3 361 4 : : : cord-292559-b21j9sf3 361 5 reinforcement reinforcement NN cord-292559-b21j9sf3 361 6 - - HYPH cord-292559-b21j9sf3 361 7 related relate VBN cord-292559-b21j9sf3 361 8 behaviour behaviour NN cord-292559-b21j9sf3 361 9 in in IN cord-292559-b21j9sf3 361 10 normal normal JJ cord-292559-b21j9sf3 361 11 brain brain NN cord-292559-b21j9sf3 361 12 function function NN cord-292559-b21j9sf3 361 13 and and CC cord-292559-b21j9sf3 361 14 psychopathology psychopathology NN cord-292559-b21j9sf3 361 15 Adolescent adolescent JJ cord-292559-b21j9sf3 361 16 brain brain NN cord-292559-b21j9sf3 361 17 cognitive cognitive JJ cord-292559-b21j9sf3 361 18 development development NN cord-292559-b21j9sf3 362 1 ( ( -LRB- cord-292559-b21j9sf3 362 2 ABCD ABCD NNP cord-292559-b21j9sf3 362 3 ) ) -RRB- cord-292559-b21j9sf3 362 4 study study NN cord-292559-b21j9sf3 362 5 : : : cord-292559-b21j9sf3 363 1 overview overview NN cord-292559-b21j9sf3 363 2 of of IN cord-292559-b21j9sf3 363 3 substance substance NN cord-292559-b21j9sf3 363 4 use use NN cord-292559-b21j9sf3 363 5 assessment assessment NN cord-292559-b21j9sf3 363 6 methods method NNS cord-292559-b21j9sf3 363 7 Adolescent adolescent JJ cord-292559-b21j9sf3 363 8 neurocognitive neurocognitive JJ cord-292559-b21j9sf3 363 9 development development NN cord-292559-b21j9sf3 363 10 and and CC cord-292559-b21j9sf3 363 11 impacts impact NNS cord-292559-b21j9sf3 363 12 of of IN cord-292559-b21j9sf3 363 13 substance substance NN cord-292559-b21j9sf3 363 14 use use NN cord-292559-b21j9sf3 363 15 : : : cord-292559-b21j9sf3 363 16 overview overview NN cord-292559-b21j9sf3 363 17 of of IN cord-292559-b21j9sf3 363 18 the the DT cord-292559-b21j9sf3 363 19 adolescent adolescent JJ cord-292559-b21j9sf3 363 20 brain brain NN cord-292559-b21j9sf3 363 21 cognitive cognitive JJ cord-292559-b21j9sf3 363 22 development development NN cord-292559-b21j9sf3 363 23 ( ( -LRB- cord-292559-b21j9sf3 363 24 ABCD ABCD NNP cord-292559-b21j9sf3 363 25 ) ) -RRB- cord-292559-b21j9sf3 364 1 baseline baseline JJ cord-292559-b21j9sf3 364 2 neurocognition neurocognition NN cord-292559-b21j9sf3 364 3 battery battery NN cord-292559-b21j9sf3 364 4 Biospecimens Biospecimens NNP cord-292559-b21j9sf3 364 5 and and CC cord-292559-b21j9sf3 364 6 the the DT cord-292559-b21j9sf3 364 7 ABCD ABCD NNP cord-292559-b21j9sf3 364 8 study study NN cord-292559-b21j9sf3 364 9 : : : cord-292559-b21j9sf3 364 10 rationale rationale NN cord-292559-b21j9sf3 364 11 , , , cord-292559-b21j9sf3 364 12 methods method NNS cord-292559-b21j9sf3 364 13 of of IN cord-292559-b21j9sf3 364 14 collection collection NN cord-292559-b21j9sf3 364 15 , , , cord-292559-b21j9sf3 364 16 measurement measurement NN cord-292559-b21j9sf3 364 17 and and CC cord-292559-b21j9sf3 364 18 early early JJ cord-292559-b21j9sf3 364 19 data data NN cord-292559-b21j9sf3 364 20 Birth Birth NNP cord-292559-b21j9sf3 364 21 cohort cohort NN cord-292559-b21j9sf3 364 22 studies study NNS cord-292559-b21j9sf3 364 23 : : : cord-292559-b21j9sf3 364 24 past past JJ cord-292559-b21j9sf3 364 25 , , , cord-292559-b21j9sf3 364 26 present present JJ cord-292559-b21j9sf3 364 27 and and CC cord-292559-b21j9sf3 364 28 future future JJ cord-292559-b21j9sf3 364 29 Implications implication NNS cord-292559-b21j9sf3 364 30 of of IN cord-292559-b21j9sf3 364 31 the the DT cord-292559-b21j9sf3 364 32 ABCD ABCD NNP cord-292559-b21j9sf3 364 33 study study NN cord-292559-b21j9sf3 364 34 for for IN cord-292559-b21j9sf3 364 35 developmental developmental JJ cord-292559-b21j9sf3 364 36 neuroscience neuroscience NN cord-292559-b21j9sf3 365 1 The the DT cord-292559-b21j9sf3 365 2 utility utility NN cord-292559-b21j9sf3 365 3 of of IN cord-292559-b21j9sf3 365 4 twins twin NNS cord-292559-b21j9sf3 365 5 in in IN cord-292559-b21j9sf3 365 6 developmental developmental JJ cord-292559-b21j9sf3 365 7 cognitive cognitive JJ cord-292559-b21j9sf3 365 8 neuroscience neuroscience NN cord-292559-b21j9sf3 365 9 research research NN cord-292559-b21j9sf3 365 10 : : : cord-292559-b21j9sf3 365 11 how how WRB cord-292559-b21j9sf3 365 12 twins twin NNS cord-292559-b21j9sf3 365 13 strengthen strengthen VBP cord-292559-b21j9sf3 365 14 the the DT cord-292559-b21j9sf3 365 15 ABCD ABCD NNP cord-292559-b21j9sf3 365 16 research research NN cord-292559-b21j9sf3 365 17 design design NN cord-292559-b21j9sf3 365 18 Adolescent adolescent JJ cord-292559-b21j9sf3 365 19 brain brain NN cord-292559-b21j9sf3 365 20 development development NN cord-292559-b21j9sf3 365 21 in in IN cord-292559-b21j9sf3 365 22 normality normality NN cord-292559-b21j9sf3 365 23 and and CC cord-292559-b21j9sf3 365 24 psychopathology psychopathology NN cord-292559-b21j9sf3 365 25 Recruiting recruit VBG cord-292559-b21j9sf3 365 26 the the DT cord-292559-b21j9sf3 365 27 ABCD ABCD NNP cord-292559-b21j9sf3 365 28 sample sample NN cord-292559-b21j9sf3 365 29 : : : cord-292559-b21j9sf3 365 30 design design NN cord-292559-b21j9sf3 365 31 considerations consideration NNS cord-292559-b21j9sf3 365 32 and and CC cord-292559-b21j9sf3 365 33 procedures procedure NNS cord-292559-b21j9sf3 365 34 Ensuring ensure VBG cord-292559-b21j9sf3 365 35 the the DT cord-292559-b21j9sf3 365 36 best good JJS cord-292559-b21j9sf3 365 37 use use NN cord-292559-b21j9sf3 365 38 of of IN cord-292559-b21j9sf3 365 39 data datum NNS cord-292559-b21j9sf3 365 40 : : : cord-292559-b21j9sf3 365 41 the the DT cord-292559-b21j9sf3 365 42 adolescent adolescent JJ cord-292559-b21j9sf3 365 43 brain brain NN cord-292559-b21j9sf3 365 44 cognitive cognitive NNP cord-292559-b21j9sf3 365 45 development development NN cord-292559-b21j9sf3 365 46 study study NN cord-292559-b21j9sf3 365 47 Approaching Approaching NNP cord-292559-b21j9sf3 365 48 Retention Retention NNP cord-292559-b21j9sf3 365 49 within within IN cord-292559-b21j9sf3 365 50 the the DT cord-292559-b21j9sf3 365 51 ABCD ABCD NNP cord-292559-b21j9sf3 365 52 Study Study NNP cord-292559-b21j9sf3 366 1 The the DT cord-292559-b21j9sf3 366 2 adolescent adolescent JJ cord-292559-b21j9sf3 366 3 brain brain NN cord-292559-b21j9sf3 366 4 cognitive cognitive JJ cord-292559-b21j9sf3 366 5 development development NN cord-292559-b21j9sf3 367 1 ( ( -LRB- cord-292559-b21j9sf3 367 2 ABCD ABCD NNP cord-292559-b21j9sf3 367 3 ) ) -RRB- cord-292559-b21j9sf3 367 4 study study NN cord-292559-b21j9sf3 367 5 : : : cord-292559-b21j9sf3 368 1 imaging imaging NN cord-292559-b21j9sf3 368 2 acquisition acquisition NN cord-292559-b21j9sf3 368 3 across across IN cord-292559-b21j9sf3 368 4 21 21 CD cord-292559-b21j9sf3 368 5 sites site NNS cord-292559-b21j9sf3 368 6 Assessment Assessment NNP cord-292559-b21j9sf3 368 7 of of IN cord-292559-b21j9sf3 368 8 culture culture NN cord-292559-b21j9sf3 368 9 and and CC cord-292559-b21j9sf3 368 10 environment environment NN cord-292559-b21j9sf3 368 11 in in IN cord-292559-b21j9sf3 368 12 the the DT cord-292559-b21j9sf3 368 13 adolescent adolescent JJ cord-292559-b21j9sf3 368 14 brain brain NN cord-292559-b21j9sf3 368 15 and and CC cord-292559-b21j9sf3 368 16 cognitive cognitive JJ cord-292559-b21j9sf3 368 17 development development NN cord-292559-b21j9sf3 368 18 study study NN cord-292559-b21j9sf3 368 19 : : : cord-292559-b21j9sf3 368 20 rationale rationale NN cord-292559-b21j9sf3 368 21 , , , cord-292559-b21j9sf3 368 22 description description NN cord-292559-b21j9sf3 368 23 of of IN cord-292559-b21j9sf3 368 24 measures measure NNS cord-292559-b21j9sf3 368 25 , , , cord-292559-b21j9sf3 368 26 and and CC cord-292559-b21j9sf3 368 27 early early JJ cord-292559-b21j9sf3 368 28 data datum NNS cord-292559-b21j9sf3 368 29 Reliability reliability NN cord-292559-b21j9sf3 368 30 of of IN cord-292559-b21j9sf3 368 31 the the DT cord-292559-b21j9sf3 368 32 timeline timeline NN cord-292559-b21j9sf3 368 33 followback followback NNP cord-292559-b21j9sf3 368 34 for for IN cord-292559-b21j9sf3 368 35 cocaine cocaine NN cord-292559-b21j9sf3 368 36 , , , cord-292559-b21j9sf3 368 37 cannabis cannabis NN cord-292559-b21j9sf3 368 38 , , , cord-292559-b21j9sf3 368 39 and and CC cord-292559-b21j9sf3 368 40 cigarette cigarette NN cord-292559-b21j9sf3 368 41 use use NN cord-292559-b21j9sf3 368 42 Timeline Timeline NNP cord-292559-b21j9sf3 368 43 follow follow VB cord-292559-b21j9sf3 368 44 back back RB cord-292559-b21j9sf3 368 45 : : : cord-292559-b21j9sf3 368 46 a a DT cord-292559-b21j9sf3 368 47 calendar calendar NN cord-292559-b21j9sf3 368 48 method method NN cord-292559-b21j9sf3 368 49 for for IN cord-292559-b21j9sf3 368 50 assessing assess VBG cord-292559-b21j9sf3 368 51 alcohol alcohol NN cord-292559-b21j9sf3 368 52 and and CC cord-292559-b21j9sf3 368 53 drug drug NN cord-292559-b21j9sf3 368 54 use use NN cord-292559-b21j9sf3 368 55 ( ( -LRB- cord-292559-b21j9sf3 368 56 User User NNP cord-292559-b21j9sf3 368 57 's 's POS cord-292559-b21j9sf3 368 58 Guide Guide NNP cord-292559-b21j9sf3 368 59 ) ) -RRB- cord-292559-b21j9sf3 368 60 . . . cord-292559-b21j9sf3 369 1 Toronto Toronto NNP cord-292559-b21j9sf3 369 2 , , , cord-292559-b21j9sf3 369 3 ON on IN cord-292559-b21j9sf3 369 4 : : : cord-292559-b21j9sf3 369 5 Canada Canada NNP cord-292559-b21j9sf3 369 6 Addiction Addiction NNP cord-292559-b21j9sf3 369 7 Research Research NNP cord-292559-b21j9sf3 369 8 Foundation Foundation NNP cord-292559-b21j9sf3 369 9 Computerized Computerized NNP cord-292559-b21j9sf3 369 10 screening screening NN cord-292559-b21j9sf3 369 11 of of IN cord-292559-b21j9sf3 369 12 comorbidity comorbidity NN cord-292559-b21j9sf3 369 13 in in IN cord-292559-b21j9sf3 369 14 adolescents adolescent NNS cord-292559-b21j9sf3 369 15 with with IN cord-292559-b21j9sf3 369 16 substance substance NN cord-292559-b21j9sf3 369 17 or or CC cord-292559-b21j9sf3 369 18 psychiatric psychiatric JJ cord-292559-b21j9sf3 369 19 disorders disorder NNS cord-292559-b21j9sf3 369 20 . . . cord-292559-b21j9sf3 370 1 Paper paper NN cord-292559-b21j9sf3 370 2 presented present VBN cord-292559-b21j9sf3 370 3 at at IN cord-292559-b21j9sf3 370 4 the the DT cord-292559-b21j9sf3 370 5 Anxiety Anxiety NNP cord-292559-b21j9sf3 370 6 Disorders Disorders NNPS cord-292559-b21j9sf3 370 7 and and CC cord-292559-b21j9sf3 370 8 Depression Depression NNP cord-292559-b21j9sf3 370 9 Conference Conference NNP cord-292559-b21j9sf3 370 10 Development Development NNP cord-292559-b21j9sf3 370 11 of of IN cord-292559-b21j9sf3 370 12 three three CD cord-292559-b21j9sf3 370 13 web web NN cord-292559-b21j9sf3 370 14 - - HYPH cord-292559-b21j9sf3 370 15 based base VBN cord-292559-b21j9sf3 370 16 computerized computerized JJ cord-292559-b21j9sf3 370 17 versions version NNS cord-292559-b21j9sf3 370 18 of of IN cord-292559-b21j9sf3 370 19 the the DT cord-292559-b21j9sf3 370 20 kiddie kiddie JJ cord-292559-b21j9sf3 370 21 schedule schedule NN cord-292559-b21j9sf3 370 22 for for IN cord-292559-b21j9sf3 370 23 affective affective JJ cord-292559-b21j9sf3 370 24 disorders disorder NNS cord-292559-b21j9sf3 370 25 and and CC cord-292559-b21j9sf3 370 26 schizophrenia schizophrenia NN cord-292559-b21j9sf3 370 27 child child NN cord-292559-b21j9sf3 370 28 psychiatric psychiatric JJ cord-292559-b21j9sf3 370 29 diagnostic diagnostic JJ cord-292559-b21j9sf3 370 30 interview interview NN cord-292559-b21j9sf3 370 31 : : : cord-292559-b21j9sf3 370 32 preliminary preliminary JJ cord-292559-b21j9sf3 370 33 validity validity NN cord-292559-b21j9sf3 370 34 data datum NNS cord-292559-b21j9sf3 370 35 Achenbach Achenbach NNP cord-292559-b21j9sf3 370 36 TM TM NNP cord-292559-b21j9sf3 370 37 . . . cord-292559-b21j9sf3 371 1 The the DT cord-292559-b21j9sf3 371 2 Achenbach Achenbach NNP cord-292559-b21j9sf3 371 3 system system NN cord-292559-b21j9sf3 371 4 of of IN cord-292559-b21j9sf3 371 5 emprically emprically RB cord-292559-b21j9sf3 371 6 based base VBN cord-292559-b21j9sf3 371 7 assessment assessment NN cord-292559-b21j9sf3 371 8 ( ( -LRB- cord-292559-b21j9sf3 371 9 ASEBA ASEBA NNP cord-292559-b21j9sf3 371 10 ) ) -RRB- cord-292559-b21j9sf3 371 11 : : : cord-292559-b21j9sf3 371 12 development development NN cord-292559-b21j9sf3 371 13 , , , cord-292559-b21j9sf3 371 14 findings finding NNS cord-292559-b21j9sf3 371 15 , , , cord-292559-b21j9sf3 371 16 theory theory NN cord-292559-b21j9sf3 371 17 and and CC cord-292559-b21j9sf3 371 18 applications application NNS cord-292559-b21j9sf3 371 19 Cognition Cognition NNP cord-292559-b21j9sf3 371 20 assessment assessment NN cord-292559-b21j9sf3 371 21 using use VBG cord-292559-b21j9sf3 371 22 the the DT cord-292559-b21j9sf3 371 23 NIH NIH NNP cord-292559-b21j9sf3 371 24 toolbox toolbox NN cord-292559-b21j9sf3 371 25 The the DT cord-292559-b21j9sf3 371 26 cognition cognition NN cord-292559-b21j9sf3 371 27 battery battery NN cord-292559-b21j9sf3 371 28 of of IN cord-292559-b21j9sf3 371 29 the the DT cord-292559-b21j9sf3 371 30 NIH NIH NNP cord-292559-b21j9sf3 371 31 toolbox toolbox NN cord-292559-b21j9sf3 371 32 for for IN cord-292559-b21j9sf3 371 33 assessment assessment NN cord-292559-b21j9sf3 371 34 of of IN cord-292559-b21j9sf3 371 35 neurological neurological JJ cord-292559-b21j9sf3 371 36 and and CC cord-292559-b21j9sf3 371 37 behavioral behavioral JJ cord-292559-b21j9sf3 371 38 function function NN cord-292559-b21j9sf3 371 39 : : : cord-292559-b21j9sf3 371 40 validation validation NN cord-292559-b21j9sf3 371 41 in in IN cord-292559-b21j9sf3 371 42 an an DT cord-292559-b21j9sf3 371 43 adult adult NN cord-292559-b21j9sf3 371 44 sample sample NN cord-292559-b21j9sf3 371 45 Image image NN cord-292559-b21j9sf3 371 46 processing processing NN cord-292559-b21j9sf3 371 47 and and CC cord-292559-b21j9sf3 371 48 analysis analysis NN cord-292559-b21j9sf3 371 49 methods method NNS cord-292559-b21j9sf3 371 50 for for IN cord-292559-b21j9sf3 371 51 the the DT cord-292559-b21j9sf3 371 52 Adolescent Adolescent NNP cord-292559-b21j9sf3 371 53 Brain Brain NNP cord-292559-b21j9sf3 371 54 Cognitive Cognitive NNP cord-292559-b21j9sf3 371 55 Development Development NNP cord-292559-b21j9sf3 371 56 Study Study NNP cord-292559-b21j9sf3 371 57 . . . cord-292559-b21j9sf3 372 1 bioRxiv biorxiv RB cord-292559-b21j9sf3 373 1 Genes gene NNS cord-292559-b21j9sf3 373 2 , , , cord-292559-b21j9sf3 373 3 maternal maternal JJ cord-292559-b21j9sf3 373 4 smoking smoking NN cord-292559-b21j9sf3 373 5 , , , cord-292559-b21j9sf3 373 6 and and CC cord-292559-b21j9sf3 373 7 the the DT cord-292559-b21j9sf3 373 8 offspring offspring NN cord-292559-b21j9sf3 373 9 brain brain NN cord-292559-b21j9sf3 373 10 and and CC cord-292559-b21j9sf3 373 11 body body NN cord-292559-b21j9sf3 373 12 during during IN cord-292559-b21j9sf3 373 13 adolescence adolescence NN cord-292559-b21j9sf3 373 14 : : : cord-292559-b21j9sf3 373 15 design design NN cord-292559-b21j9sf3 373 16 of of IN cord-292559-b21j9sf3 373 17 the the DT cord-292559-b21j9sf3 373 18 Saguenay Saguenay NNP cord-292559-b21j9sf3 373 19 Youth Youth NNP cord-292559-b21j9sf3 373 20 Study Study NNP cord-292559-b21j9sf3 374 1 The the DT cord-292559-b21j9sf3 374 2 NIH NIH NNP cord-292559-b21j9sf3 374 3 MRI MRI NNP cord-292559-b21j9sf3 374 4 study study NN cord-292559-b21j9sf3 374 5 of of IN cord-292559-b21j9sf3 374 6 normal normal JJ cord-292559-b21j9sf3 374 7 brain brain NN cord-292559-b21j9sf3 374 8 development development NN cord-292559-b21j9sf3 375 1 The the DT cord-292559-b21j9sf3 375 2 pediatric pediatric JJ cord-292559-b21j9sf3 375 3 imaging imaging NN cord-292559-b21j9sf3 375 4 , , , cord-292559-b21j9sf3 375 5 neurocognition neurocognition NN cord-292559-b21j9sf3 375 6 , , , cord-292559-b21j9sf3 375 7 and and CC cord-292559-b21j9sf3 375 8 genetics genetic NNS cord-292559-b21j9sf3 375 9 ( ( -LRB- cord-292559-b21j9sf3 375 10 PING ping NN cord-292559-b21j9sf3 375 11 ) ) -RRB- cord-292559-b21j9sf3 375 12 data data NN cord-292559-b21j9sf3 375 13 repository repository NN cord-292559-b21j9sf3 376 1 A a DT cord-292559-b21j9sf3 376 2 multi multi JJ cord-292559-b21j9sf3 376 3 - - JJ cord-292559-b21j9sf3 376 4 modal modal JJ cord-292559-b21j9sf3 376 5 parcellation parcellation NN cord-292559-b21j9sf3 376 6 of of IN cord-292559-b21j9sf3 376 7 human human JJ cord-292559-b21j9sf3 376 8 cerebral cerebral JJ cord-292559-b21j9sf3 376 9 cortex cortex NNP cord-292559-b21j9sf3 377 1 The the DT cord-292559-b21j9sf3 377 2 Human Human NNP cord-292559-b21j9sf3 377 3 Connectome Connectome NNP cord-292559-b21j9sf3 377 4 Project Project NNP cord-292559-b21j9sf3 377 5 : : : cord-292559-b21j9sf3 377 6 a a DT cord-292559-b21j9sf3 377 7 data data NN cord-292559-b21j9sf3 377 8 acquisition acquisition NN cord-292559-b21j9sf3 377 9 perspective perspective NN cord-292559-b21j9sf3 378 1 The the DT cord-292559-b21j9sf3 378 2 lifespan lifespan NN cord-292559-b21j9sf3 378 3 human human JJ cord-292559-b21j9sf3 378 4 connectome connectome NN cord-292559-b21j9sf3 378 5 project project NN cord-292559-b21j9sf3 378 6 in in IN cord-292559-b21j9sf3 378 7 development development NN cord-292559-b21j9sf3 378 8 : : : cord-292559-b21j9sf3 378 9 a a DT cord-292559-b21j9sf3 378 10 large large JJ cord-292559-b21j9sf3 378 11 - - HYPH cord-292559-b21j9sf3 378 12 scale scale NN cord-292559-b21j9sf3 378 13 study study NN cord-292559-b21j9sf3 378 14 of of IN cord-292559-b21j9sf3 378 15 brain brain NN cord-292559-b21j9sf3 378 16 connectivity connectivity NN cord-292559-b21j9sf3 378 17 development development NN cord-292559-b21j9sf3 378 18 in in IN cord-292559-b21j9sf3 378 19 5 5 CD cord-292559-b21j9sf3 378 20 - - SYM cord-292559-b21j9sf3 378 21 21 21 CD cord-292559-b21j9sf3 378 22 year year NN cord-292559-b21j9sf3 378 23 olds old NNS cord-292559-b21j9sf3 378 24 UK UK NNP cord-292559-b21j9sf3 378 25 biobank biobank NNP cord-292559-b21j9sf3 378 26 : : : cord-292559-b21j9sf3 378 27 an an DT cord-292559-b21j9sf3 378 28 open open JJ cord-292559-b21j9sf3 378 29 access access NN cord-292559-b21j9sf3 378 30 resource resource NN cord-292559-b21j9sf3 378 31 for for IN cord-292559-b21j9sf3 378 32 identifying identify VBG cord-292559-b21j9sf3 378 33 the the DT cord-292559-b21j9sf3 378 34 causes cause NNS cord-292559-b21j9sf3 378 35 of of IN cord-292559-b21j9sf3 378 36 a a DT cord-292559-b21j9sf3 378 37 wide wide JJ cord-292559-b21j9sf3 378 38 range range NN cord-292559-b21j9sf3 378 39 of of IN cord-292559-b21j9sf3 378 40 complex complex JJ cord-292559-b21j9sf3 378 41 diseases disease NNS cord-292559-b21j9sf3 378 42 of of IN cord-292559-b21j9sf3 378 43 middle middle JJ cord-292559-b21j9sf3 378 44 and and CC cord-292559-b21j9sf3 378 45 old old JJ cord-292559-b21j9sf3 378 46 age age NN cord-292559-b21j9sf3 379 1 The the DT cord-292559-b21j9sf3 379 2 Philadelphia Philadelphia NNP cord-292559-b21j9sf3 379 3 Neurodevelopmental Neurodevelopmental NNP cord-292559-b21j9sf3 379 4 Cohort Cohort NNP cord-292559-b21j9sf3 379 5 : : : cord-292559-b21j9sf3 379 6 a a DT cord-292559-b21j9sf3 379 7 publicly publicly RB cord-292559-b21j9sf3 379 8 available available JJ cord-292559-b21j9sf3 379 9 resource resource NN cord-292559-b21j9sf3 379 10 for for IN cord-292559-b21j9sf3 379 11 the the DT cord-292559-b21j9sf3 379 12 study study NN cord-292559-b21j9sf3 379 13 of of IN cord-292559-b21j9sf3 379 14 normal normal JJ cord-292559-b21j9sf3 379 15 and and CC cord-292559-b21j9sf3 379 16 abnormal abnormal JJ cord-292559-b21j9sf3 379 17 brain brain NN cord-292559-b21j9sf3 379 18 development development NN cord-292559-b21j9sf3 379 19 in in IN cord-292559-b21j9sf3 379 20 youth youth NN cord-292559-b21j9sf3 380 1 The the DT cord-292559-b21j9sf3 380 2 Dunedin Dunedin NNP cord-292559-b21j9sf3 380 3 Multidisciplinary Multidisciplinary NNP cord-292559-b21j9sf3 380 4 Health Health NNP cord-292559-b21j9sf3 380 5 and and CC cord-292559-b21j9sf3 380 6 Development Development NNP cord-292559-b21j9sf3 380 7 Study Study NNP cord-292559-b21j9sf3 380 8 : : : cord-292559-b21j9sf3 380 9 overview overview NN cord-292559-b21j9sf3 380 10 of of IN cord-292559-b21j9sf3 380 11 the the DT cord-292559-b21j9sf3 380 12 first first JJ cord-292559-b21j9sf3 380 13 40 40 CD cord-292559-b21j9sf3 380 14 years year NNS cord-292559-b21j9sf3 380 15 , , , cord-292559-b21j9sf3 380 16 with with IN cord-292559-b21j9sf3 380 17 an an DT cord-292559-b21j9sf3 380 18 eye eye NN cord-292559-b21j9sf3 380 19 to to IN cord-292559-b21j9sf3 380 20 the the DT cord-292559-b21j9sf3 380 21 future future NN cord-292559-b21j9sf3 381 1 An an DT cord-292559-b21j9sf3 381 2 item item NN cord-292559-b21j9sf3 381 3 response response NN cord-292559-b21j9sf3 381 4 theory theory NN cord-292559-b21j9sf3 381 5 analysis analysis NN cord-292559-b21j9sf3 381 6 of of IN cord-292559-b21j9sf3 381 7 the the DT cord-292559-b21j9sf3 381 8 prodromal prodromal JJ cord-292559-b21j9sf3 381 9 questionnaire questionnaire NN cord-292559-b21j9sf3 381 10 - - HYPH cord-292559-b21j9sf3 381 11 brief brief JJ cord-292559-b21j9sf3 381 12 child child NN cord-292559-b21j9sf3 381 13 version version NN cord-292559-b21j9sf3 381 14 : : : cord-292559-b21j9sf3 381 15 developing develop VBG cord-292559-b21j9sf3 381 16 a a DT cord-292559-b21j9sf3 381 17 screening screening NN cord-292559-b21j9sf3 381 18 form form NN cord-292559-b21j9sf3 381 19 that that WDT cord-292559-b21j9sf3 381 20 informs inform VBZ cord-292559-b21j9sf3 381 21 understanding understanding NN cord-292559-b21j9sf3 381 22 of of IN cord-292559-b21j9sf3 381 23 self self NN cord-292559-b21j9sf3 381 24 - - HYPH cord-292559-b21j9sf3 381 25 reported report VBN cord-292559-b21j9sf3 381 26 psychotic psychotic JJ cord-292559-b21j9sf3 381 27 - - HYPH cord-292559-b21j9sf3 381 28 like like JJ cord-292559-b21j9sf3 381 29 experiences experience NNS cord-292559-b21j9sf3 381 30 in in IN cord-292559-b21j9sf3 381 31 childhood childhood NN cord-292559-b21j9sf3 381 32 Sleep Sleep NNP cord-292559-b21j9sf3 381 33 duration duration NN cord-292559-b21j9sf3 381 34 , , , cord-292559-b21j9sf3 381 35 brain brain NN cord-292559-b21j9sf3 381 36 structure structure NN cord-292559-b21j9sf3 381 37 , , , cord-292559-b21j9sf3 381 38 and and CC cord-292559-b21j9sf3 381 39 psychiatric psychiatric JJ cord-292559-b21j9sf3 381 40 and and CC cord-292559-b21j9sf3 381 41 cognitive cognitive JJ cord-292559-b21j9sf3 381 42 problems problem NNS cord-292559-b21j9sf3 381 43 in in IN cord-292559-b21j9sf3 381 44 children child NNS cord-292559-b21j9sf3 381 45 . . . cord-292559-b21j9sf3 382 1 Mol Mol NNP cord-292559-b21j9sf3 382 2 Psychiatry Psychiatry NNP cord-292559-b21j9sf3 382 3 Assessing assess VBG cord-292559-b21j9sf3 382 4 callous callous JJ cord-292559-b21j9sf3 382 5 - - HYPH cord-292559-b21j9sf3 382 6 unemotional unemotional JJ cord-292559-b21j9sf3 382 7 traits trait NNS cord-292559-b21j9sf3 382 8 : : : cord-292559-b21j9sf3 382 9 development development NN cord-292559-b21j9sf3 382 10 of of IN cord-292559-b21j9sf3 382 11 a a DT cord-292559-b21j9sf3 382 12 brief brief JJ cord-292559-b21j9sf3 382 13 , , , cord-292559-b21j9sf3 382 14 reliable reliable JJ cord-292559-b21j9sf3 382 15 measure measure NN cord-292559-b21j9sf3 382 16 in in IN cord-292559-b21j9sf3 382 17 a a DT cord-292559-b21j9sf3 382 18 large large JJ cord-292559-b21j9sf3 382 19 and and CC cord-292559-b21j9sf3 382 20 diverse diverse JJ cord-292559-b21j9sf3 382 21 sample sample NN cord-292559-b21j9sf3 382 22 of of IN cord-292559-b21j9sf3 382 23 preadolescent preadolescent JJ cord-292559-b21j9sf3 382 24 youth youth NN cord-292559-b21j9sf3 382 25 Replication Replication NNP cord-292559-b21j9sf3 382 26 of of IN cord-292559-b21j9sf3 382 27 associations association NNS cord-292559-b21j9sf3 382 28 with with IN cord-292559-b21j9sf3 382 29 psychotic psychotic JJ cord-292559-b21j9sf3 382 30 - - HYPH cord-292559-b21j9sf3 382 31 like like JJ cord-292559-b21j9sf3 382 32 experiences experience NNS cord-292559-b21j9sf3 382 33 in in IN cord-292559-b21j9sf3 382 34 middle middle JJ cord-292559-b21j9sf3 382 35 childhood childhood NN cord-292559-b21j9sf3 382 36 from from IN cord-292559-b21j9sf3 382 37 the the DT cord-292559-b21j9sf3 382 38 adolescent adolescent JJ cord-292559-b21j9sf3 382 39 brain brain NN cord-292559-b21j9sf3 382 40 cognitive cognitive JJ cord-292559-b21j9sf3 382 41 development development NN cord-292559-b21j9sf3 382 42 ( ( -LRB- cord-292559-b21j9sf3 382 43 ABCD ABCD NNP cord-292559-b21j9sf3 382 44 ) ) -RRB- cord-292559-b21j9sf3 382 45 study study NN cord-292559-b21j9sf3 383 1 Identifying identify VBG cord-292559-b21j9sf3 383 2 reproducible reproducible JJ cord-292559-b21j9sf3 383 3 individual individual JJ cord-292559-b21j9sf3 383 4 differences difference NNS cord-292559-b21j9sf3 383 5 in in IN cord-292559-b21j9sf3 383 6 childhood childhood NN cord-292559-b21j9sf3 383 7 functional functional JJ cord-292559-b21j9sf3 383 8 brain brain NN cord-292559-b21j9sf3 383 9 networks network NNS cord-292559-b21j9sf3 383 10 : : : cord-292559-b21j9sf3 384 1 an an DT cord-292559-b21j9sf3 384 2 ABCD ABCD NNP cord-292559-b21j9sf3 384 3 study study NN cord-292559-b21j9sf3 384 4 Brain Brain NNP cord-292559-b21j9sf3 384 5 volume volume NN cord-292559-b21j9sf3 384 6 abnormalities abnormality NNS cord-292559-b21j9sf3 384 7 in in IN cord-292559-b21j9sf3 384 8 youth youth NN cord-292559-b21j9sf3 384 9 at at IN cord-292559-b21j9sf3 384 10 high high JJ cord-292559-b21j9sf3 384 11 risk risk NN cord-292559-b21j9sf3 384 12 for for IN cord-292559-b21j9sf3 384 13 depression depression NN cord-292559-b21j9sf3 384 14 : : : cord-292559-b21j9sf3 384 15 adolescent adolescent JJ cord-292559-b21j9sf3 384 16 brain brain NN cord-292559-b21j9sf3 384 17 and and CC cord-292559-b21j9sf3 384 18 cognitive cognitive NNP cord-292559-b21j9sf3 384 19 development development NN cord-292559-b21j9sf3 384 20 study study NN cord-292559-b21j9sf3 384 21 . . . cord-292559-b21j9sf3 385 1 J J NNP cord-292559-b21j9sf3 385 2 Am Am NNP cord-292559-b21j9sf3 385 3 Acad Acad NNP cord-292559-b21j9sf3 385 4 Child Child NNP cord-292559-b21j9sf3 385 5 Adolesc Adolesc NNP cord-292559-b21j9sf3 385 6 Psychiatry Psychiatry NNP cord-292559-b21j9sf3 385 7 Assessment Assessment NNP cord-292559-b21j9sf3 385 8 of of IN cord-292559-b21j9sf3 385 9 the the DT cord-292559-b21j9sf3 385 10 prodromal prodromal JJ cord-292559-b21j9sf3 385 11 questionnaire questionnaire NN cord-292559-b21j9sf3 385 12 - - HYPH cord-292559-b21j9sf3 385 13 brief brief JJ cord-292559-b21j9sf3 385 14 child child NN cord-292559-b21j9sf3 385 15 version version NN cord-292559-b21j9sf3 385 16 for for IN cord-292559-b21j9sf3 385 17 measurement measurement NN cord-292559-b21j9sf3 385 18 of of IN cord-292559-b21j9sf3 385 19 self self NN cord-292559-b21j9sf3 385 20 - - HYPH cord-292559-b21j9sf3 385 21 reported report VBN cord-292559-b21j9sf3 385 22 psychoticlike psychoticlike JJ cord-292559-b21j9sf3 385 23 experiences experience NNS cord-292559-b21j9sf3 385 24 in in IN cord-292559-b21j9sf3 385 25 childhood childhood NN cord-292559-b21j9sf3 385 26 Factor Factor NNP cord-292559-b21j9sf3 385 27 structure structure NN cord-292559-b21j9sf3 385 28 , , , cord-292559-b21j9sf3 385 29 measurement measurement NN cord-292559-b21j9sf3 385 30 and and CC cord-292559-b21j9sf3 385 31 structural structural JJ cord-292559-b21j9sf3 385 32 invariance invariance NN cord-292559-b21j9sf3 385 33 , , , cord-292559-b21j9sf3 385 34 and and CC cord-292559-b21j9sf3 385 35 external external JJ cord-292559-b21j9sf3 385 36 validity validity NN cord-292559-b21j9sf3 385 37 of of IN cord-292559-b21j9sf3 385 38 an an DT cord-292559-b21j9sf3 385 39 abbreviated abbreviated JJ cord-292559-b21j9sf3 385 40 youth youth NN cord-292559-b21j9sf3 385 41 version version NN cord-292559-b21j9sf3 385 42 of of IN cord-292559-b21j9sf3 385 43 the the DT cord-292559-b21j9sf3 385 44 UPPS UPPS NNP cord-292559-b21j9sf3 385 45 - - HYPH cord-292559-b21j9sf3 385 46 P p NN cord-292559-b21j9sf3 385 47 impulsive impulsive JJ cord-292559-b21j9sf3 385 48 behavior behavior NN cord-292559-b21j9sf3 385 49 scale scale NN cord-292559-b21j9sf3 385 50 Prevalence prevalence NN cord-292559-b21j9sf3 385 51 and and CC cord-292559-b21j9sf3 385 52 correlates correlate NNS cord-292559-b21j9sf3 385 53 of of IN cord-292559-b21j9sf3 385 54 maladaptive maladaptive JJ cord-292559-b21j9sf3 385 55 guilt guilt NN cord-292559-b21j9sf3 385 56 in in IN cord-292559-b21j9sf3 385 57 middle middle JJ cord-292559-b21j9sf3 385 58 childhood childhood NN cord-292559-b21j9sf3 385 59 Prevalence prevalence NN cord-292559-b21j9sf3 385 60 of of IN cord-292559-b21j9sf3 385 61 eating eat VBG cord-292559-b21j9sf3 385 62 disorders disorder NNS cord-292559-b21j9sf3 385 63 among among IN cord-292559-b21j9sf3 385 64 US US NNP cord-292559-b21j9sf3 385 65 children child NNS cord-292559-b21j9sf3 385 66 aged age VBN cord-292559-b21j9sf3 385 67 9 9 CD cord-292559-b21j9sf3 385 68 to to TO cord-292559-b21j9sf3 385 69 10 10 CD cord-292559-b21j9sf3 385 70 years year NNS cord-292559-b21j9sf3 385 71 : : : cord-292559-b21j9sf3 385 72 data datum NNS cord-292559-b21j9sf3 385 73 from from IN cord-292559-b21j9sf3 385 74 the the DT cord-292559-b21j9sf3 385 75 adolescent adolescent JJ cord-292559-b21j9sf3 385 76 brain brain NN cord-292559-b21j9sf3 385 77 cognitive cognitive JJ cord-292559-b21j9sf3 385 78 development development NN cord-292559-b21j9sf3 385 79 ( ( -LRB- cord-292559-b21j9sf3 385 80 ABCD ABCD NNP cord-292559-b21j9sf3 385 81 ) ) -RRB- cord-292559-b21j9sf3 385 82 study study NN cord-292559-b21j9sf3 385 83 Prevalence prevalence NN cord-292559-b21j9sf3 385 84 and and CC cord-292559-b21j9sf3 385 85 family family NN cord-292559-b21j9sf3 385 86 - - HYPH cord-292559-b21j9sf3 385 87 related relate VBN cord-292559-b21j9sf3 385 88 factors factor NNS cord-292559-b21j9sf3 385 89 associated associate VBN cord-292559-b21j9sf3 385 90 with with IN cord-292559-b21j9sf3 385 91 suicidal suicidal JJ cord-292559-b21j9sf3 385 92 ideation ideation NN cord-292559-b21j9sf3 385 93 , , , cord-292559-b21j9sf3 385 94 suicide suicide NN cord-292559-b21j9sf3 385 95 attempts attempt NNS cord-292559-b21j9sf3 385 96 , , , cord-292559-b21j9sf3 385 97 and and CC cord-292559-b21j9sf3 385 98 self self NN cord-292559-b21j9sf3 385 99 - - HYPH cord-292559-b21j9sf3 385 100 injury injury NN cord-292559-b21j9sf3 385 101 in in IN cord-292559-b21j9sf3 385 102 children child NNS cord-292559-b21j9sf3 385 103 aged age VBN cord-292559-b21j9sf3 385 104 9 9 CD cord-292559-b21j9sf3 385 105 to to TO cord-292559-b21j9sf3 385 106 10 10 CD cord-292559-b21j9sf3 385 107 years year NNS cord-292559-b21j9sf3 385 108 Association Association NNP cord-292559-b21j9sf3 385 109 of of IN cord-292559-b21j9sf3 385 110 prenatal prenatal JJ cord-292559-b21j9sf3 385 111 cannabis cannabis NN cord-292559-b21j9sf3 385 112 exposure exposure NN cord-292559-b21j9sf3 385 113 with with IN cord-292559-b21j9sf3 385 114 psychosis psychosis NN cord-292559-b21j9sf3 385 115 proneness proneness NN cord-292559-b21j9sf3 385 116 among among IN cord-292559-b21j9sf3 385 117 children child NNS cord-292559-b21j9sf3 385 118 in in IN cord-292559-b21j9sf3 385 119 the the DT cord-292559-b21j9sf3 385 120 Adolescent Adolescent NNP cord-292559-b21j9sf3 385 121 Brain Brain NNP cord-292559-b21j9sf3 385 122 Cognitive Cognitive NNP cord-292559-b21j9sf3 385 123 Development Development NNP cord-292559-b21j9sf3 386 1 ( ( -LRB- cord-292559-b21j9sf3 386 2 ABCD ABCD NNP cord-292559-b21j9sf3 386 3 ) ) -RRB- cord-292559-b21j9sf3 386 4 Study Study NNP cord-292559-b21j9sf3 386 5 Demographic Demographic NNP cord-292559-b21j9sf3 386 6 , , , cord-292559-b21j9sf3 386 7 psychological psychological JJ cord-292559-b21j9sf3 386 8 , , , cord-292559-b21j9sf3 386 9 behavioral behavioral JJ cord-292559-b21j9sf3 386 10 , , , cord-292559-b21j9sf3 386 11 and and CC cord-292559-b21j9sf3 386 12 cognitive cognitive JJ cord-292559-b21j9sf3 386 13 correlates correlate NNS cord-292559-b21j9sf3 386 14 of of IN cord-292559-b21j9sf3 386 15 BMI BMI NNP cord-292559-b21j9sf3 386 16 in in IN cord-292559-b21j9sf3 386 17 youth youth NN cord-292559-b21j9sf3 386 18 : : : cord-292559-b21j9sf3 387 1 findings finding NNS cord-292559-b21j9sf3 387 2 from from IN cord-292559-b21j9sf3 387 3 the the DT cord-292559-b21j9sf3 387 4 Adolescent Adolescent NNP cord-292559-b21j9sf3 387 5 Brain Brain NNP cord-292559-b21j9sf3 387 6 Cognitive Cognitive NNP cord-292559-b21j9sf3 387 7 Development Development NNP cord-292559-b21j9sf3 387 8 ( ( -LRB- cord-292559-b21j9sf3 387 9 ABCD ABCD NNP cord-292559-b21j9sf3 387 10 ) ) -RRB- cord-292559-b21j9sf3 387 11 study study VB cord-292559-b21j9sf3 387 12 Child child NN cord-292559-b21j9sf3 387 13 sexual sexual JJ cord-292559-b21j9sf3 387 14 orientation orientation NN cord-292559-b21j9sf3 387 15 and and CC cord-292559-b21j9sf3 387 16 gender gender NN cord-292559-b21j9sf3 387 17 identity identity NN cord-292559-b21j9sf3 387 18 in in IN cord-292559-b21j9sf3 387 19 the the DT cord-292559-b21j9sf3 387 20 Adolescent Adolescent NNP cord-292559-b21j9sf3 387 21 Brain Brain NNP cord-292559-b21j9sf3 387 22 Cognitive Cognitive NNP cord-292559-b21j9sf3 387 23 Development Development NNP cord-292559-b21j9sf3 387 24 Cohort Cohort NNP cord-292559-b21j9sf3 387 25 Study Study NNP cord-292559-b21j9sf3 387 26 Sexual sexual JJ cord-292559-b21j9sf3 387 27 minority minority NN cord-292559-b21j9sf3 387 28 children child NNS cord-292559-b21j9sf3 387 29 : : : cord-292559-b21j9sf3 387 30 mood mood NN cord-292559-b21j9sf3 387 31 disorders disorder NNS cord-292559-b21j9sf3 387 32 and and CC cord-292559-b21j9sf3 387 33 suicidality suicidality NN cord-292559-b21j9sf3 387 34 disparities disparity NNS cord-292559-b21j9sf3 388 1 The the DT cord-292559-b21j9sf3 388 2 structure structure NN cord-292559-b21j9sf3 388 3 of of IN cord-292559-b21j9sf3 388 4 cognition cognition NN cord-292559-b21j9sf3 388 5 in in IN cord-292559-b21j9sf3 388 6 9 9 CD cord-292559-b21j9sf3 388 7 and and CC cord-292559-b21j9sf3 388 8 10 10 CD cord-292559-b21j9sf3 388 9 year year NN cord-292559-b21j9sf3 388 10 - - HYPH cord-292559-b21j9sf3 388 11 old old JJ cord-292559-b21j9sf3 388 12 children child NNS cord-292559-b21j9sf3 388 13 and and CC cord-292559-b21j9sf3 388 14 associations association NNS cord-292559-b21j9sf3 388 15 with with IN cord-292559-b21j9sf3 388 16 problem problem NN cord-292559-b21j9sf3 388 17 behaviors behavior NNS cord-292559-b21j9sf3 388 18 : : : cord-292559-b21j9sf3 388 19 findings finding NNS cord-292559-b21j9sf3 388 20 from from IN cord-292559-b21j9sf3 388 21 the the DT cord-292559-b21j9sf3 388 22 ABCD ABCD NNP cord-292559-b21j9sf3 388 23 study study NN cord-292559-b21j9sf3 388 24 's 's POS cord-292559-b21j9sf3 388 25 baseline baseline JJ cord-292559-b21j9sf3 388 26 neurocognitive neurocognitive JJ cord-292559-b21j9sf3 388 27 battery battery NN cord-292559-b21j9sf3 389 1 No no DT cord-292559-b21j9sf3 389 2 evidence evidence NN cord-292559-b21j9sf3 389 3 for for IN cord-292559-b21j9sf3 389 4 a a DT cord-292559-b21j9sf3 389 5 bilingual bilingual JJ cord-292559-b21j9sf3 389 6 executive executive JJ cord-292559-b21j9sf3 389 7 function function NN cord-292559-b21j9sf3 389 8 advantage advantage NN cord-292559-b21j9sf3 389 9 in in IN cord-292559-b21j9sf3 389 10 the the DT cord-292559-b21j9sf3 389 11 nationally nationally RB cord-292559-b21j9sf3 389 12 representative representative JJ cord-292559-b21j9sf3 389 13 ABCD ABCD NNP cord-292559-b21j9sf3 389 14 study study NN cord-292559-b21j9sf3 389 15 Associations association NNS cord-292559-b21j9sf3 389 16 between between IN cord-292559-b21j9sf3 389 17 24 24 CD cord-292559-b21j9sf3 389 18 h h NNP cord-292559-b21j9sf3 389 19 movement movement NN cord-292559-b21j9sf3 389 20 behaviours behaviour NNS cord-292559-b21j9sf3 389 21 and and CC cord-292559-b21j9sf3 389 22 global global JJ cord-292559-b21j9sf3 389 23 cognition cognition NN cord-292559-b21j9sf3 389 24 in in IN cord-292559-b21j9sf3 389 25 US US NNP cord-292559-b21j9sf3 389 26 children child NNS cord-292559-b21j9sf3 389 27 : : : cord-292559-b21j9sf3 389 28 a a DT cord-292559-b21j9sf3 389 29 cross cross JJ cord-292559-b21j9sf3 389 30 - - JJ cord-292559-b21j9sf3 389 31 sectional sectional JJ cord-292559-b21j9sf3 389 32 observational observational JJ cord-292559-b21j9sf3 389 33 study study NN cord-292559-b21j9sf3 389 34 Prediction Prediction NNP cord-292559-b21j9sf3 389 35 of of IN cord-292559-b21j9sf3 389 36 neurocognition neurocognition NN cord-292559-b21j9sf3 389 37 in in IN cord-292559-b21j9sf3 389 38 youth youth NN cord-292559-b21j9sf3 389 39 from from IN cord-292559-b21j9sf3 389 40 resting rest VBG cord-292559-b21j9sf3 389 41 state state NN cord-292559-b21j9sf3 389 42 fMRI fMRI NNP cord-292559-b21j9sf3 389 43 . . . cord-292559-b21j9sf3 390 1 Mol Mol NNP cord-292559-b21j9sf3 390 2 Psychiatry Psychiatry NNP cord-292559-b21j9sf3 390 3 Association Association NNP cord-292559-b21j9sf3 390 4 of of IN cord-292559-b21j9sf3 390 5 lead lead NN cord-292559-b21j9sf3 390 6 - - HYPH cord-292559-b21j9sf3 390 7 exposure exposure NN cord-292559-b21j9sf3 390 8 risk risk NN cord-292559-b21j9sf3 390 9 and and CC cord-292559-b21j9sf3 390 10 family family NN cord-292559-b21j9sf3 390 11 income income NN cord-292559-b21j9sf3 390 12 with with IN cord-292559-b21j9sf3 390 13 childhood childhood NN cord-292559-b21j9sf3 390 14 brain brain NN cord-292559-b21j9sf3 390 15 outcomes outcome NNS cord-292559-b21j9sf3 391 1 Screen screen NN cord-292559-b21j9sf3 391 2 media medium NNS cord-292559-b21j9sf3 391 3 activity activity NN cord-292559-b21j9sf3 391 4 and and CC cord-292559-b21j9sf3 391 5 brain brain NN cord-292559-b21j9sf3 391 6 structure structure NN cord-292559-b21j9sf3 391 7 in in IN cord-292559-b21j9sf3 391 8 youth youth NN cord-292559-b21j9sf3 391 9 : : : cord-292559-b21j9sf3 391 10 evidence evidence NN cord-292559-b21j9sf3 391 11 for for IN cord-292559-b21j9sf3 391 12 diverse diverse JJ cord-292559-b21j9sf3 391 13 structural structural JJ cord-292559-b21j9sf3 391 14 correlation correlation NN cord-292559-b21j9sf3 391 15 networks network NNS cord-292559-b21j9sf3 391 16 from from IN cord-292559-b21j9sf3 391 17 the the DT cord-292559-b21j9sf3 391 18 ABCD ABCD NNP cord-292559-b21j9sf3 391 19 study study NN cord-292559-b21j9sf3 391 20 Associations association NNS cord-292559-b21j9sf3 391 21 among among IN cord-292559-b21j9sf3 391 22 body body NN cord-292559-b21j9sf3 391 23 mass mass NN cord-292559-b21j9sf3 391 24 index index NN cord-292559-b21j9sf3 391 25 , , , cord-292559-b21j9sf3 391 26 cortical cortical JJ cord-292559-b21j9sf3 391 27 thickness thickness NN cord-292559-b21j9sf3 391 28 , , , cord-292559-b21j9sf3 391 29 and and CC cord-292559-b21j9sf3 391 30 executive executive JJ cord-292559-b21j9sf3 391 31 function function NN cord-292559-b21j9sf3 391 32 in in IN cord-292559-b21j9sf3 391 33 children child NNS cord-292559-b21j9sf3 391 34 Childhood Childhood NNP cord-292559-b21j9sf3 391 35 obesity obesity NN cord-292559-b21j9sf3 391 36 , , , cord-292559-b21j9sf3 391 37 cortical cortical JJ cord-292559-b21j9sf3 391 38 structure structure NN cord-292559-b21j9sf3 391 39 , , , cord-292559-b21j9sf3 391 40 and and CC cord-292559-b21j9sf3 391 41 executive executive JJ cord-292559-b21j9sf3 391 42 function function NN cord-292559-b21j9sf3 391 43 in in IN cord-292559-b21j9sf3 391 44 healthy healthy JJ cord-292559-b21j9sf3 391 45 children child NNS cord-292559-b21j9sf3 391 46 Involvement Involvement NNP cord-292559-b21j9sf3 391 47 in in IN cord-292559-b21j9sf3 391 48 sports sport NNS cord-292559-b21j9sf3 391 49 , , , cord-292559-b21j9sf3 391 50 hippocampal hippocampal JJ cord-292559-b21j9sf3 391 51 volume volume NN cord-292559-b21j9sf3 391 52 , , , cord-292559-b21j9sf3 391 53 and and CC cord-292559-b21j9sf3 391 54 depressive depressive JJ cord-292559-b21j9sf3 391 55 symptoms symptom NNS cord-292559-b21j9sf3 391 56 in in IN cord-292559-b21j9sf3 391 57 children child NNS cord-292559-b21j9sf3 391 58 Association Association NNP cord-292559-b21j9sf3 391 59 between between IN cord-292559-b21j9sf3 391 60 childhood childhood NN cord-292559-b21j9sf3 391 61 anhedonia anhedonia NN cord-292559-b21j9sf3 391 62 and and CC cord-292559-b21j9sf3 391 63 alterations alteration NNS cord-292559-b21j9sf3 391 64 in in IN cord-292559-b21j9sf3 391 65 large large JJ cord-292559-b21j9sf3 391 66 - - HYPH cord-292559-b21j9sf3 391 67 scale scale NN cord-292559-b21j9sf3 391 68 resting resting NN cord-292559-b21j9sf3 391 69 - - HYPH cord-292559-b21j9sf3 391 70 state state NN cord-292559-b21j9sf3 391 71 networks network NNS cord-292559-b21j9sf3 391 72 and and CC cord-292559-b21j9sf3 391 73 task task NN cord-292559-b21j9sf3 391 74 - - HYPH cord-292559-b21j9sf3 391 75 evoked evoke VBN cord-292559-b21j9sf3 391 76 activation activation NN cord-292559-b21j9sf3 391 77 Resting rest VBG cord-292559-b21j9sf3 391 78 - - HYPH cord-292559-b21j9sf3 391 79 state state NN cord-292559-b21j9sf3 391 80 functional functional JJ cord-292559-b21j9sf3 391 81 connectivity connectivity NN cord-292559-b21j9sf3 391 82 and and CC cord-292559-b21j9sf3 391 83 psychotic psychotic JJ cord-292559-b21j9sf3 391 84 - - HYPH cord-292559-b21j9sf3 391 85 like like JJ cord-292559-b21j9sf3 391 86 experiences experience NNS cord-292559-b21j9sf3 391 87 in in IN cord-292559-b21j9sf3 391 88 childhood childhood NN cord-292559-b21j9sf3 391 89 : : : cord-292559-b21j9sf3 392 1 results result NNS cord-292559-b21j9sf3 392 2 from from IN cord-292559-b21j9sf3 392 3 the the DT cord-292559-b21j9sf3 392 4 Adolescent Adolescent NNP cord-292559-b21j9sf3 392 5 Brain Brain NNP cord-292559-b21j9sf3 392 6 Cognitive Cognitive NNP cord-292559-b21j9sf3 392 7 Development Development NNP cord-292559-b21j9sf3 392 8 Study Study NNP cord-292559-b21j9sf3 392 9 Disruptive disruptive JJ cord-292559-b21j9sf3 392 10 behavior behavior NN cord-292559-b21j9sf3 392 11 problems problem NNS cord-292559-b21j9sf3 392 12 , , , cord-292559-b21j9sf3 392 13 callous callous JJ cord-292559-b21j9sf3 392 14 - - HYPH cord-292559-b21j9sf3 392 15 unemotional unemotional JJ cord-292559-b21j9sf3 392 16 traits trait NNS cord-292559-b21j9sf3 392 17 , , , cord-292559-b21j9sf3 392 18 and and CC cord-292559-b21j9sf3 392 19 regional regional JJ cord-292559-b21j9sf3 392 20 gray gray JJ cord-292559-b21j9sf3 392 21 matter matter NN cord-292559-b21j9sf3 392 22 volume volume NN cord-292559-b21j9sf3 392 23 in in IN cord-292559-b21j9sf3 392 24 the the DT cord-292559-b21j9sf3 392 25 Adolescent Adolescent NNP cord-292559-b21j9sf3 392 26 Brain Brain NNP cord-292559-b21j9sf3 392 27 and and CC cord-292559-b21j9sf3 392 28 Cognitive Cognitive NNP cord-292559-b21j9sf3 392 29 Development Development NNP cord-292559-b21j9sf3 392 30 Study Study NNP cord-292559-b21j9sf3 392 31 Statistical statistical JJ cord-292559-b21j9sf3 392 32 challenges challenge NNS cord-292559-b21j9sf3 392 33 in in IN cord-292559-b21j9sf3 392 34 " " `` cord-292559-b21j9sf3 392 35 big big JJ cord-292559-b21j9sf3 392 36 data datum NNS cord-292559-b21j9sf3 392 37 " " '' cord-292559-b21j9sf3 392 38 human human JJ cord-292559-b21j9sf3 392 39 neuroimaging neuroimage VBG cord-292559-b21j9sf3 392 40 Mental mental JJ cord-292559-b21j9sf3 392 41 health health NN cord-292559-b21j9sf3 392 42 surveillance surveillance NN cord-292559-b21j9sf3 392 43 among among IN cord-292559-b21j9sf3 392 44 children child NNS cord-292559-b21j9sf3 392 45 - - : cord-292559-b21j9sf3 392 46 United United NNP cord-292559-b21j9sf3 392 47 States States NNP cord-292559-b21j9sf3 393 1 Predicting predict VBG cord-292559-b21j9sf3 393 2 psychosis psychosis NN cord-292559-b21j9sf3 393 3 : : : cord-292559-b21j9sf3 393 4 meta meta NN cord-292559-b21j9sf3 393 5 - - HYPH cord-292559-b21j9sf3 393 6 analysis analysis NN cord-292559-b21j9sf3 393 7 of of IN cord-292559-b21j9sf3 393 8 transition transition NN cord-292559-b21j9sf3 393 9 outcomes outcome NNS cord-292559-b21j9sf3 393 10 in in IN cord-292559-b21j9sf3 393 11 individuals individual NNS cord-292559-b21j9sf3 393 12 at at IN cord-292559-b21j9sf3 393 13 high high JJ cord-292559-b21j9sf3 393 14 clinical clinical JJ cord-292559-b21j9sf3 393 15 risk risk NN cord-292559-b21j9sf3 393 16 Power Power NNP cord-292559-b21j9sf3 393 17 failure failure NN cord-292559-b21j9sf3 393 18 : : : cord-292559-b21j9sf3 393 19 why why WRB cord-292559-b21j9sf3 393 20 small small JJ cord-292559-b21j9sf3 393 21 sample sample NN cord-292559-b21j9sf3 393 22 size size NN cord-292559-b21j9sf3 393 23 undermines undermine VBZ cord-292559-b21j9sf3 393 24 the the DT cord-292559-b21j9sf3 393 25 reliability reliability NN cord-292559-b21j9sf3 393 26 of of IN cord-292559-b21j9sf3 394 1 neuroscience neuroscience NNP cord-292559-b21j9sf3 394 2 An an DT cord-292559-b21j9sf3 394 3 investigation investigation NN cord-292559-b21j9sf3 394 4 of of IN cord-292559-b21j9sf3 394 5 the the DT cord-292559-b21j9sf3 394 6 false false JJ cord-292559-b21j9sf3 394 7 discovery discovery NN cord-292559-b21j9sf3 394 8 rate rate NN cord-292559-b21j9sf3 394 9 and and CC cord-292559-b21j9sf3 394 10 the the DT cord-292559-b21j9sf3 394 11 misinterpretation misinterpretation NN cord-292559-b21j9sf3 394 12 of of IN cord-292559-b21j9sf3 394 13 p p NN cord-292559-b21j9sf3 394 14 - - HYPH cord-292559-b21j9sf3 394 15 values value NNS cord-292559-b21j9sf3 394 16 Robust robust JJ cord-292559-b21j9sf3 394 17 research research NN cord-292559-b21j9sf3 394 18 : : : cord-292559-b21j9sf3 394 19 institutions institution NNS cord-292559-b21j9sf3 394 20 must must MD cord-292559-b21j9sf3 394 21 do do VB cord-292559-b21j9sf3 394 22 their -PRON- PRP$ cord-292559-b21j9sf3 394 23 part part NN cord-292559-b21j9sf3 394 24 for for IN cord-292559-b21j9sf3 394 25 reproducibility reproducibility NN cord-292559-b21j9sf3 394 26 Getting get VBG cord-292559-b21j9sf3 394 27 rigorous rigorous JJ cord-292559-b21j9sf3 394 28 with with IN cord-292559-b21j9sf3 394 29 scientific scientific JJ cord-292559-b21j9sf3 394 30 rigor rigor NN cord-292559-b21j9sf3 394 31 Examining examine VBG cord-292559-b21j9sf3 394 32 the the DT cord-292559-b21j9sf3 394 33 current current JJ cord-292559-b21j9sf3 394 34 standards standard NNS cord-292559-b21j9sf3 394 35 for for IN cord-292559-b21j9sf3 394 36 genetic genetic JJ cord-292559-b21j9sf3 394 37 discovery discovery NN cord-292559-b21j9sf3 394 38 and and CC cord-292559-b21j9sf3 394 39 replication replication NN cord-292559-b21j9sf3 394 40 in in IN cord-292559-b21j9sf3 394 41 the the DT cord-292559-b21j9sf3 394 42 era era NN cord-292559-b21j9sf3 394 43 of of IN cord-292559-b21j9sf3 394 44 mega mega NNS cord-292559-b21j9sf3 394 45 - - NNS cord-292559-b21j9sf3 394 46 biobanks biobank NNS cord-292559-b21j9sf3 394 47 p p NN cord-292559-b21j9sf3 394 48 - - HYPH cord-292559-b21j9sf3 394 49 Curve curve NN cord-292559-b21j9sf3 394 50 and and CC cord-292559-b21j9sf3 394 51 p p NN cord-292559-b21j9sf3 394 52 - - HYPH cord-292559-b21j9sf3 394 53 Hacking hacking NN cord-292559-b21j9sf3 394 54 in in IN cord-292559-b21j9sf3 394 55 observational observational JJ cord-292559-b21j9sf3 394 56 research research NN cord-292559-b21j9sf3 394 57 Scanning scan VBG cord-292559-b21j9sf3 394 58 the the DT cord-292559-b21j9sf3 394 59 horizon horizon NN cord-292559-b21j9sf3 394 60 : : : cord-292559-b21j9sf3 394 61 towards towards IN cord-292559-b21j9sf3 394 62 transparent transparent JJ cord-292559-b21j9sf3 394 63 and and CC cord-292559-b21j9sf3 394 64 reproducible reproducible JJ cord-292559-b21j9sf3 394 65 neuroimaging neuroimaging NN cord-292559-b21j9sf3 394 66 research research NN cord-292559-b21j9sf3 394 67 Basic Basic NNP cord-292559-b21j9sf3 394 68 Functions Functions NNPS cord-292559-b21j9sf3 394 69 for for IN cord-292559-b21j9sf3 394 70 Power Power NNP cord-292559-b21j9sf3 394 71 Analysis Analysis NNP cord-292559-b21j9sf3 395 1 A a DT cord-292559-b21j9sf3 395 2 guide guide NN cord-292559-b21j9sf3 395 3 for for IN cord-292559-b21j9sf3 395 4 population population NN cord-292559-b21j9sf3 395 5 - - HYPH cord-292559-b21j9sf3 395 6 based base VBN cord-292559-b21j9sf3 395 7 analysis analysis NN cord-292559-b21j9sf3 395 8 of of IN cord-292559-b21j9sf3 395 9 the the DT cord-292559-b21j9sf3 395 10 Adolescent Adolescent NNP cord-292559-b21j9sf3 395 11 Brain Brain NNP cord-292559-b21j9sf3 395 12 Cognitive Cognitive NNP cord-292559-b21j9sf3 395 13 Development Development NNP cord-292559-b21j9sf3 395 14 ( ( -LRB- cord-292559-b21j9sf3 395 15 ABCD ABCD NNP cord-292559-b21j9sf3 395 16 ) ) -RRB- cord-292559-b21j9sf3 396 1 Study Study NNP cord-292559-b21j9sf3 396 2 Baseline Baseline NNP cord-292559-b21j9sf3 396 3 Data Data NNP cord-292559-b21j9sf3 396 4 Psychology Psychology NNP cord-292559-b21j9sf3 396 5 's 's POS cord-292559-b21j9sf3 396 6 replication replication NN cord-292559-b21j9sf3 396 7 crisis crisis NN cord-292559-b21j9sf3 396 8 and and CC cord-292559-b21j9sf3 396 9 the the DT cord-292559-b21j9sf3 396 10 grant grant NN cord-292559-b21j9sf3 396 11 culture culture NN cord-292559-b21j9sf3 396 12 : : : cord-292559-b21j9sf3 396 13 righting right VBG cord-292559-b21j9sf3 396 14 the the DT cord-292559-b21j9sf3 396 15 ship ship NN cord-292559-b21j9sf3 396 16 Cross Cross NNP cord-292559-b21j9sf3 396 17 - - NN cord-292559-b21j9sf3 396 18 validation validation NN cord-292559-b21j9sf3 396 19 approaches approach NNS cord-292559-b21j9sf3 396 20 for for IN cord-292559-b21j9sf3 396 21 replicability replicability NN cord-292559-b21j9sf3 396 22 in in IN cord-292559-b21j9sf3 396 23 psychology psychology NN cord-292559-b21j9sf3 397 1 The the DT cord-292559-b21j9sf3 397 2 lifespan lifespan NN cord-292559-b21j9sf3 397 3 human human JJ cord-292559-b21j9sf3 397 4 connectome connectome NN cord-292559-b21j9sf3 397 5 project project NN cord-292559-b21j9sf3 397 6 in in IN cord-292559-b21j9sf3 397 7 aging age VBG cord-292559-b21j9sf3 397 8 : : : cord-292559-b21j9sf3 397 9 an an DT cord-292559-b21j9sf3 397 10 overview overview NN cord-292559-b21j9sf3 397 11 Brain Brain NNP cord-292559-b21j9sf3 397 12 development development NN cord-292559-b21j9sf3 397 13 during during IN cord-292559-b21j9sf3 397 14 childhood childhood NN cord-292559-b21j9sf3 397 15 and and CC cord-292559-b21j9sf3 397 16 adolescence adolescence NN cord-292559-b21j9sf3 397 17 : : : cord-292559-b21j9sf3 397 18 a a DT cord-292559-b21j9sf3 397 19 longitudinal longitudinal JJ cord-292559-b21j9sf3 397 20 MRI MRI NNP cord-292559-b21j9sf3 397 21 study study NN cord-292559-b21j9sf3 398 1 The the DT cord-292559-b21j9sf3 398 2 importance importance NN cord-292559-b21j9sf3 398 3 of of IN cord-292559-b21j9sf3 398 4 puberty puberty NN cord-292559-b21j9sf3 398 5 for for IN cord-292559-b21j9sf3 398 6 adolescent adolescent JJ cord-292559-b21j9sf3 398 7 development development NN cord-292559-b21j9sf3 398 8 : : : cord-292559-b21j9sf3 398 9 conceptualization conceptualization NN cord-292559-b21j9sf3 398 10 and and CC cord-292559-b21j9sf3 398 11 measurement measurement NN cord-292559-b21j9sf3 398 12 Adolescence adolescence NN cord-292559-b21j9sf3 398 13 , , , cord-292559-b21j9sf3 398 14 brain brain NN cord-292559-b21j9sf3 398 15 maturation maturation NN cord-292559-b21j9sf3 398 16 and and CC cord-292559-b21j9sf3 398 17 mental mental JJ cord-292559-b21j9sf3 398 18 health health NN cord-292559-b21j9sf3 398 19 Cortisol Cortisol NNP cord-292559-b21j9sf3 398 20 and and CC cord-292559-b21j9sf3 398 21 DHEA DHEA NNP cord-292559-b21j9sf3 398 22 in in IN cord-292559-b21j9sf3 398 23 development development NN cord-292559-b21j9sf3 398 24 and and CC cord-292559-b21j9sf3 398 25 psychopathology psychopathology NN cord-292559-b21j9sf3 399 1 The the DT cord-292559-b21j9sf3 399 2 new new JJ cord-292559-b21j9sf3 399 3 life life NN cord-292559-b21j9sf3 399 4 stage stage NN cord-292559-b21j9sf3 399 5 of of IN cord-292559-b21j9sf3 399 6 emerging emerge VBG cord-292559-b21j9sf3 399 7 adulthood adulthood NN cord-292559-b21j9sf3 399 8 at at IN cord-292559-b21j9sf3 399 9 ages age NNS cord-292559-b21j9sf3 399 10 18 18 CD cord-292559-b21j9sf3 399 11 - - SYM cord-292559-b21j9sf3 399 12 29 29 CD cord-292559-b21j9sf3 399 13 years year NNS cord-292559-b21j9sf3 399 14 : : : cord-292559-b21j9sf3 399 15 implications implication NNS cord-292559-b21j9sf3 399 16 for for IN cord-292559-b21j9sf3 399 17 mental mental JJ cord-292559-b21j9sf3 399 18 health health NN cord-292559-b21j9sf3 400 1 The the DT cord-292559-b21j9sf3 400 2 life life NN cord-292559-b21j9sf3 400 3 course course NN cord-292559-b21j9sf3 400 4 as as IN cord-292559-b21j9sf3 400 5 developmental developmental JJ cord-292559-b21j9sf3 400 6 theory theory NN cord-292559-b21j9sf3 400 7 Developmental developmental JJ cord-292559-b21j9sf3 400 8 psychopathology psychopathology NN cord-292559-b21j9sf3 400 9 , , , cord-292559-b21j9sf3 400 10 volume volume NN cord-292559-b21j9sf3 400 11 1 1 CD cord-292559-b21j9sf3 400 12 : : : cord-292559-b21j9sf3 400 13 theory theory NN cord-292559-b21j9sf3 400 14 and and CC cord-292559-b21j9sf3 400 15 method method NN cord-292559-b21j9sf3 401 1 The the DT cord-292559-b21j9sf3 401 2 effects effect NNS cord-292559-b21j9sf3 401 3 of of IN cord-292559-b21j9sf3 401 4 poverty poverty NN cord-292559-b21j9sf3 401 5 on on IN cord-292559-b21j9sf3 401 6 childhood childhood NN cord-292559-b21j9sf3 401 7 brain brain NN cord-292559-b21j9sf3 401 8 development development NN cord-292559-b21j9sf3 401 9 : : : cord-292559-b21j9sf3 401 10 the the DT cord-292559-b21j9sf3 401 11 mediating mediating JJ cord-292559-b21j9sf3 401 12 effect effect NN cord-292559-b21j9sf3 401 13 of of IN cord-292559-b21j9sf3 401 14 caregiving caregiving NN cord-292559-b21j9sf3 401 15 and and CC cord-292559-b21j9sf3 401 16 stressful stressful JJ cord-292559-b21j9sf3 401 17 life life NN cord-292559-b21j9sf3 401 18 events event NNS cord-292559-b21j9sf3 402 1 Adverse adverse JJ cord-292559-b21j9sf3 402 2 childhood childhood NN cord-292559-b21j9sf3 402 3 experiences experience NNS cord-292559-b21j9sf3 402 4 and and CC cord-292559-b21j9sf3 402 5 the the DT cord-292559-b21j9sf3 402 6 lifelong lifelong JJ cord-292559-b21j9sf3 402 7 consequences consequence NNS cord-292559-b21j9sf3 402 8 of of IN cord-292559-b21j9sf3 402 9 trauma trauma NN cord-292559-b21j9sf3 402 10 Children Children NNP cord-292559-b21j9sf3 402 11 's 's POS cord-292559-b21j9sf3 402 12 physical physical JJ cord-292559-b21j9sf3 402 13 activity activity NN cord-292559-b21j9sf3 402 14 and and CC cord-292559-b21j9sf3 402 15 depression depression NN cord-292559-b21j9sf3 402 16 : : : cord-292559-b21j9sf3 402 17 a a DT cord-292559-b21j9sf3 402 18 meta meta NN cord-292559-b21j9sf3 402 19 - - HYPH cord-292559-b21j9sf3 402 20 analysis analysis NN cord-292559-b21j9sf3 402 21 The the DT cord-292559-b21j9sf3 402 22 association association NN cord-292559-b21j9sf3 402 23 between between IN cord-292559-b21j9sf3 402 24 social social JJ cord-292559-b21j9sf3 402 25 support support NNP cord-292559-b21j9sf3 402 26 and and CC cord-292559-b21j9sf3 402 27 mental mental JJ cord-292559-b21j9sf3 402 28 health health NN cord-292559-b21j9sf3 402 29 among among IN cord-292559-b21j9sf3 402 30 vulnerable vulnerable JJ cord-292559-b21j9sf3 402 31 adolescents adolescent NNS cord-292559-b21j9sf3 402 32 in in IN cord-292559-b21j9sf3 402 33 five five CD cord-292559-b21j9sf3 402 34 cities city NNS cord-292559-b21j9sf3 402 35 : : : cord-292559-b21j9sf3 402 36 findings finding NNS cord-292559-b21j9sf3 402 37 from from IN cord-292559-b21j9sf3 402 38 the the DT cord-292559-b21j9sf3 402 39 study study NN cord-292559-b21j9sf3 402 40 of of IN cord-292559-b21j9sf3 402 41 the the DT cord-292559-b21j9sf3 402 42 well well NN cord-292559-b21j9sf3 402 43 - - HYPH cord-292559-b21j9sf3 402 44 being being NN cord-292559-b21j9sf3 402 45 of of IN cord-292559-b21j9sf3 402 46 adolescents adolescent NNS cord-292559-b21j9sf3 402 47 in in IN cord-292559-b21j9sf3 402 48 vulnerable vulnerable JJ cord-292559-b21j9sf3 402 49 environments environment NNS cord-292559-b21j9sf3 402 50 Coping cope VBG cord-292559-b21j9sf3 402 51 with with IN cord-292559-b21j9sf3 402 52 depressive depressive JJ cord-292559-b21j9sf3 402 53 symptoms symptom NNS cord-292559-b21j9sf3 402 54 in in IN cord-292559-b21j9sf3 402 55 young young JJ cord-292559-b21j9sf3 402 56 adults adult NNS cord-292559-b21j9sf3 403 1 : : : cord-292559-b21j9sf3 403 2 perceived perceive VBN cord-292559-b21j9sf3 403 3 social social JJ cord-292559-b21j9sf3 403 4 support support NN cord-292559-b21j9sf3 403 5 protects protect VBZ cord-292559-b21j9sf3 403 6 against against IN cord-292559-b21j9sf3 403 7 depressive depressive JJ cord-292559-b21j9sf3 403 8 symptoms symptom NNS cord-292559-b21j9sf3 403 9 only only RB cord-292559-b21j9sf3 403 10 under under IN cord-292559-b21j9sf3 403 11 moderate moderate JJ cord-292559-b21j9sf3 403 12 levels level NNS cord-292559-b21j9sf3 403 13 of of IN cord-292559-b21j9sf3 403 14 stress stress NN cord-292559-b21j9sf3 403 15 Editorial editorial NN cord-292559-b21j9sf3 403 16 : : : cord-292559-b21j9sf3 403 17 back back RB cord-292559-b21j9sf3 403 18 to to IN cord-292559-b21j9sf3 403 19 the the DT cord-292559-b21j9sf3 403 20 future future NN cord-292559-b21j9sf3 403 21 : : : cord-292559-b21j9sf3 403 22 on on IN cord-292559-b21j9sf3 403 23 the the DT cord-292559-b21j9sf3 403 24 road road NN cord-292559-b21j9sf3 403 25 towards towards IN cord-292559-b21j9sf3 403 26 precision precision NN cord-292559-b21j9sf3 403 27 psychiatry psychiatry NN cord-292559-b21j9sf3 403 28 . . . cord-292559-b21j9sf3 404 1 Front front JJ cord-292559-b21j9sf3 404 2 psychiatry psychiatry NN cord-292559-b21j9sf3 404 3 Psychopathology psychopathology NN cord-292559-b21j9sf3 404 4 - - : cord-292559-b21j9sf3 404 5 a a DT cord-292559-b21j9sf3 404 6 precision precision NN cord-292559-b21j9sf3 404 7 tool tool NN cord-292559-b21j9sf3 404 8 in in IN cord-292559-b21j9sf3 404 9 need need NN cord-292559-b21j9sf3 404 10 of of IN cord-292559-b21j9sf3 404 11 re re NN cord-292559-b21j9sf3 404 12 - - NN cord-292559-b21j9sf3 404 13 sharpening sharpening NN cord-292559-b21j9sf3 404 14 . . . cord-292559-b21j9sf3 405 1 Front front JJ cord-292559-b21j9sf3 405 2 psychiatry psychiatry NN cord-292559-b21j9sf3 405 3 Deep deep JJ cord-292559-b21j9sf3 405 4 phenotyping phenotyping NN cord-292559-b21j9sf3 405 5 for for IN cord-292559-b21j9sf3 405 6 precision precision NN cord-292559-b21j9sf3 405 7 medicine medicine NN cord-292559-b21j9sf3 405 8 Developmental developmental JJ cord-292559-b21j9sf3 405 9 psychopathology psychopathology NN cord-292559-b21j9sf3 405 10 : : : cord-292559-b21j9sf3 406 1 recent recent JJ cord-292559-b21j9sf3 406 2 advances advance NNS cord-292559-b21j9sf3 406 3 and and CC cord-292559-b21j9sf3 406 4 future future JJ cord-292559-b21j9sf3 406 5 challenges challenge NNS cord-292559-b21j9sf3 406 6 Current current JJ cord-292559-b21j9sf3 406 7 , , , cord-292559-b21j9sf3 406 8 future future NN cord-292559-b21j9sf3 406 9 and and CC cord-292559-b21j9sf3 406 10 potential potential JJ cord-292559-b21j9sf3 406 11 use use NN cord-292559-b21j9sf3 406 12 of of IN cord-292559-b21j9sf3 406 13 mobile mobile JJ cord-292559-b21j9sf3 406 14 and and CC cord-292559-b21j9sf3 406 15 wearable wearable JJ cord-292559-b21j9sf3 406 16 technologies technology NNS cord-292559-b21j9sf3 406 17 and and CC cord-292559-b21j9sf3 406 18 social social JJ cord-292559-b21j9sf3 406 19 media medium NNS cord-292559-b21j9sf3 406 20 data datum NNS cord-292559-b21j9sf3 406 21 in in IN cord-292559-b21j9sf3 406 22 the the DT cord-292559-b21j9sf3 406 23 ABCD ABCD NNP cord-292559-b21j9sf3 406 24 study study NN cord-292559-b21j9sf3 406 25 to to TO cord-292559-b21j9sf3 406 26 increase increase VB cord-292559-b21j9sf3 406 27 understanding understanding NN cord-292559-b21j9sf3 406 28 of of IN cord-292559-b21j9sf3 406 29 contributors contributor NNS cord-292559-b21j9sf3 406 30 to to IN cord-292559-b21j9sf3 406 31 child child NN cord-292559-b21j9sf3 406 32 health health NN cord-292559-b21j9sf3 406 33 Social Social NNP cord-292559-b21j9sf3 406 34 media medium NNS cord-292559-b21j9sf3 406 35 use use NN cord-292559-b21j9sf3 406 36 and and CC cord-292559-b21j9sf3 406 37 risky risky JJ cord-292559-b21j9sf3 406 38 behaviors behavior NNS cord-292559-b21j9sf3 406 39 in in IN cord-292559-b21j9sf3 406 40 adolescents adolescent NNS cord-292559-b21j9sf3 406 41 : : : cord-292559-b21j9sf3 406 42 a a DT cord-292559-b21j9sf3 406 43 meta meta JJ cord-292559-b21j9sf3 406 44 - - HYPH cord-292559-b21j9sf3 406 45 analysis analysis NN cord-292559-b21j9sf3 406 46 Annual annual JJ cord-292559-b21j9sf3 406 47 research research NN cord-292559-b21j9sf3 406 48 review review NN cord-292559-b21j9sf3 406 49 : : : cord-292559-b21j9sf3 406 50 adolescent adolescent JJ cord-292559-b21j9sf3 406 51 mental mental JJ cord-292559-b21j9sf3 406 52 health health NN cord-292559-b21j9sf3 406 53 in in IN cord-292559-b21j9sf3 406 54 the the DT cord-292559-b21j9sf3 406 55 digital digital JJ cord-292559-b21j9sf3 406 56 age age NN cord-292559-b21j9sf3 406 57 : : : cord-292559-b21j9sf3 406 58 facts fact NNS cord-292559-b21j9sf3 406 59 , , , cord-292559-b21j9sf3 406 60 fears fear NNS cord-292559-b21j9sf3 406 61 , , , cord-292559-b21j9sf3 406 62 and and CC cord-292559-b21j9sf3 406 63 future future JJ cord-292559-b21j9sf3 406 64 directions direction NNS cord-292559-b21j9sf3 407 1 Sleep sleep VB cord-292559-b21j9sf3 407 2 disturbance disturbance NN cord-292559-b21j9sf3 407 3 in in IN cord-292559-b21j9sf3 407 4 mental mental JJ cord-292559-b21j9sf3 407 5 health health NN cord-292559-b21j9sf3 407 6 problems problem NNS cord-292559-b21j9sf3 407 7 and and CC cord-292559-b21j9sf3 407 8 neurodegenerative neurodegenerative JJ cord-292559-b21j9sf3 407 9 disease disease NN cord-292559-b21j9sf3 407 10 Sleep Sleep NNP cord-292559-b21j9sf3 407 11 disturbances disturbance NNS cord-292559-b21j9sf3 407 12 in in IN cord-292559-b21j9sf3 407 13 child child NN cord-292559-b21j9sf3 407 14 and and CC cord-292559-b21j9sf3 407 15 adolescent adolescent JJ cord-292559-b21j9sf3 407 16 mental mental JJ cord-292559-b21j9sf3 407 17 health health NN cord-292559-b21j9sf3 407 18 disorders disorder NNS cord-292559-b21j9sf3 407 19 : : : cord-292559-b21j9sf3 408 1 a a DT cord-292559-b21j9sf3 408 2 review review NN cord-292559-b21j9sf3 408 3 of of IN cord-292559-b21j9sf3 408 4 the the DT cord-292559-b21j9sf3 408 5 variability variability NN cord-292559-b21j9sf3 408 6 of of IN cord-292559-b21j9sf3 408 7 objective objective JJ cord-292559-b21j9sf3 408 8 sleep sleep NN cord-292559-b21j9sf3 408 9 markers marker NNS cord-292559-b21j9sf3 408 10 Physical physical JJ cord-292559-b21j9sf3 408 11 activity activity NN cord-292559-b21j9sf3 408 12 and and CC cord-292559-b21j9sf3 408 13 weight weight NN cord-292559-b21j9sf3 408 14 gain gain NN cord-292559-b21j9sf3 408 15 prevention prevention NN cord-292559-b21j9sf3 408 16 Childhood childhood NN cord-292559-b21j9sf3 408 17 externalizing externalize VBG cord-292559-b21j9sf3 408 18 and and CC cord-292559-b21j9sf3 408 19 internalizing internalize VBG cord-292559-b21j9sf3 408 20 psychopathology psychopathology NN cord-292559-b21j9sf3 408 21 in in IN cord-292559-b21j9sf3 408 22 the the DT cord-292559-b21j9sf3 408 23 prediction prediction NN cord-292559-b21j9sf3 408 24 of of IN cord-292559-b21j9sf3 408 25 early early JJ cord-292559-b21j9sf3 408 26 substance substance NN cord-292559-b21j9sf3 408 27 use use NN cord-292559-b21j9sf3 408 28 Peer Peer NNP cord-292559-b21j9sf3 408 29 network network NN cord-292559-b21j9sf3 408 30 drinking drinking NN cord-292559-b21j9sf3 408 31 predicts predict VBZ cord-292559-b21j9sf3 408 32 increased increased JJ cord-292559-b21j9sf3 408 33 alcohol alcohol NN cord-292559-b21j9sf3 408 34 use use NN cord-292559-b21j9sf3 408 35 from from IN cord-292559-b21j9sf3 408 36 adolescence adolescence NN cord-292559-b21j9sf3 408 37 to to IN cord-292559-b21j9sf3 408 38 early early JJ cord-292559-b21j9sf3 408 39 adulthood adulthood NN cord-292559-b21j9sf3 408 40 after after IN cord-292559-b21j9sf3 408 41 controlling control VBG cord-292559-b21j9sf3 408 42 for for IN cord-292559-b21j9sf3 408 43 genetic genetic JJ cord-292559-b21j9sf3 408 44 and and CC cord-292559-b21j9sf3 408 45 shared share VBN cord-292559-b21j9sf3 408 46 environmental environmental JJ cord-292559-b21j9sf3 408 47 selection selection NN cord-292559-b21j9sf3 408 48 Gene gene NN cord-292559-b21j9sf3 408 49 - - HYPH cord-292559-b21j9sf3 408 50 environment environment NN cord-292559-b21j9sf3 408 51 interaction interaction NN cord-292559-b21j9sf3 408 52 in in IN cord-292559-b21j9sf3 408 53 psychological psychological JJ cord-292559-b21j9sf3 408 54 traits trait NNS cord-292559-b21j9sf3 408 55 and and CC cord-292559-b21j9sf3 408 56 disorders disorder NNS cord-292559-b21j9sf3 409 1 The the DT cord-292559-b21j9sf3 409 2 impact impact NN cord-292559-b21j9sf3 409 3 of of IN cord-292559-b21j9sf3 409 4 gene gene NN cord-292559-b21j9sf3 409 5 - - HYPH cord-292559-b21j9sf3 409 6 environment environment NN cord-292559-b21j9sf3 409 7 interaction interaction NN cord-292559-b21j9sf3 409 8 on on IN cord-292559-b21j9sf3 409 9 alcohol alcohol NN cord-292559-b21j9sf3 409 10 use use NN cord-292559-b21j9sf3 409 11 disorders disorder NNS cord-292559-b21j9sf3 409 12 Polygenic Polygenic NNP cord-292559-b21j9sf3 409 13 risk risk NN cord-292559-b21j9sf3 409 14 scores score NNS cord-292559-b21j9sf3 409 15 in in IN cord-292559-b21j9sf3 409 16 clinical clinical JJ cord-292559-b21j9sf3 409 17 psychology psychology NN cord-292559-b21j9sf3 409 18 : : : cord-292559-b21j9sf3 409 19 bridging bridge VBG cord-292559-b21j9sf3 409 20 genomic genomic JJ cord-292559-b21j9sf3 409 21 risk risk NN cord-292559-b21j9sf3 409 22 to to IN cord-292559-b21j9sf3 409 23 individual individual JJ cord-292559-b21j9sf3 409 24 differences difference NNS