id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-329770-tz8dwgzm	Hamer, Mark	Lifestyle Risk Factors, Inflammatory Mechanisms, and COVID-19 Hospitalization: A Community-Based Cohort Study of 387,109 Adults in UK	2020-05-23		.txt	text/plain	2408	133	49	We conducted the first large-scale general population study on lifestyle risk factors (smoking, physical inactivity, obesity, and excessive alcohol intake) for COVID-19 using prospective cohort data with national registry linkage to hospitalisation. After adjustment for age, sex and mutually for each lifestyle factor, physical inactivity (Relative risk, 1.32, 95% confidence interval, 1.10, 1.58), smoking (1.42;1.12, 1.79) and obesity (2.05 ;1.68, 2.49) but not heavy alcohol consumption (1.12; 0.93, 1.35) were all related to COVID-19. Accordingly, we examined the association of lifestyle risk factors with new cases of COVID-19-hospitalisations in a general population-based cohort study. 9 Our results suggested both overweight and obesity were risk factors for severe COVID-19 infection, consistent with emerging data in small clinical studies. Our data suggests low grade inflammation was a risk factor for severe COVID-19, and partially explained links between lifestyle behaviors and infection. Lifestyle risk factors, obesity and infectious disease mortality in the general population: Linkage study of 97,844 adults from England and Scotland	./cache/cord-329770-tz8dwgzm.txt	./txt/cord-329770-tz8dwgzm.txt