id author title date pages extension mime words sentences flesch summary cache txt cord-292559-b21j9sf3 Karcher, Nicole R. The ABCD study: understanding the development of risk for mental and physical health outcomes 2020-06-15 .txt text/plain 10081 447 36 The initial goal of the ABCD Study was to examine risk and resiliency factors associated with the development of substance use, but the project has expanded far beyond this initial set of questions and will also greatly inform our understanding of the contributions of biospecimens (e.g., pubertal hormones), neural alterations, and environmental factors to the development of both healthy behavior and brain function as well as risk for poor mental and physical outcomes. First, the ABCD Study utilized a school-based national recruitment strategy with limited exclusion criteria, helping to overcome challenges to previous general population studies that generally did not include neuroimaging [10] as well as attempts to understand the risk factors associated with negative outcomes that relied on convenience samples [11] . These studies provide important evidence that the ABCD Study sample can be leveraged to conduct rigorous research practices, including examining the psychometric evidence for using existing (or newly created) measures in a middle childhood sample, supporting the use of these measures to better understand the development of risk. ./cache/cord-292559-b21j9sf3.txt ./txt/cord-292559-b21j9sf3.txt