id author title date pages extension mime words sentences flesch summary cache txt cord-277800-dtpsiaj9 Stefan, Norbert Metabolically Healthy and Unhealthy Normal Weight and Obesity 2020-08-20 .txt text/plain 3260 150 48 Whether impaired metabolic health, characterized by hypertension, dyslipidemia, hyperglycemia, insulin resistance, and subclinical inflammation, may explain part of the elevated risk of cardiometabolic diseases that is found in many subjects with very low fat mass, as it does in many obese subjects, is unknown. For example in an analysis of 323,175 adults from the large Korean National Health Insurance System (NHIS) database, who were followedup for a median of 96 months, subjects with MHO even had a lower all-cause (-19%) and cardiovascular (-27%) mortality risk, when compared to non-obese and metabolically healthy subjects. Data from the North West Adelaide Health Study suggest that risk of diabetes, CVD, or stroke is not increased in people with MHO compared to people with MHNW, if the metabolically healthy obesity phenotype is maintained during a natural follow-up over 5.5 to 10.3 years [31] . Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease (CVD) risk across body mass index categories in 90,257 women of the Nurses' Health Study. ./cache/cord-277800-dtpsiaj9.txt ./txt/cord-277800-dtpsiaj9.txt