id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001064-59i3jert	Ashbolt, Nicholas J.	Human Health Risk Assessment (HHRA) for Environmental Development and Transfer of Antibiotic Resistance	2013-07-09		.txt	text/plain	9146	392	37	• Clinical and environmental surveillance programs for anti biotics, ARB, and their determinants, with a focus on regional data volume 121 | number 9 | September 2013 • Environmental Health Perspectives reporting the types and use of anti biotics in human medicine, crops, and commercial and companion animals, as well as globally where crops and food animals are produced • Epidemiological investigations of outbreaks and sporadic cases associated with ARB, including clinical studies on the occurrence, frequency, and severity of ARB infections • Identification of the selection pressures (time and dose of selecting/coselecting agents) required to select for resistance in differ ent environments, and subsequent HGT to humanrelevant bacteria, both based on reports describing the frequency of HGT and uptake of ARG into environmental bac teria, including environmental pathogens, in previously identified hot spots • Human, laboratory, and/or field animal/crop trials addressing the link between anti biotic use and resistance (particularly regional data) • Investigations of the characteristics of ARB and their determinants (ex situ and in situ) • Studies on the link between resistance, viru lence, and/or ecological fitness (e.g., surviv ability or adaptability) of ARB • Studies on the environmental fate of anti biotic residues in water and soil and their bioavailability associated with the selection of ARB in any given environmental com partment, animal, or human host result ing in pARB • Existing risk assessments of ARB and related pathogens.	./cache/cord-001064-59i3jert.txt	./txt/cord-001064-59i3jert.txt