id author title date pages extension mime words sentences flesch summary cache txt cord-269377-ylgyvxtd Matos, Ana R. COVID-19 Associated Central Nervous System Vasculopathy 2020-06-02 .txt text/plain 939 57 38 Stroke in the setting of viral vasculopathy has been described with other viruses, such as varicella zoster virus (VZV) or 1 ; more recently, it has also been associated with other coronavirus, namely, Middle East respiratory syndrome coronavirus, during the outbreak in Saudi Arabia in 2012. The imaging presentation of multiple lesions involving deep and subcortical white matter, as well as deep gray nuclei, with marked restricted diffusion of some, has been described in the setting of VZV vasculopathy. Primary angiitis of the central nervous system was also considered, but the absence of obvious large vessel irregularities, normal CSF cellular count, and concomitant SARS-CoV-2 infection led us consider a COVID-19-related vasculopathy as the most probable diagnosis, potentially induced by misdirected immune mediated-vasoconstriction of medium-/ small-sized arteries; we believe this represents a new imaging presentation of a SARS-CoV-2-related complication. ./cache/cord-269377-ylgyvxtd.txt ./txt/cord-269377-ylgyvxtd.txt