id	sid	tid	token	lemma	pos
cord-285778-80baxwgc	1	1	key	key	NN
cord-285778-80baxwgc	1	2	:	:	:
cord-285778-80baxwgc	2	1	cord-285778	cord-285778	NNP
cord-285778-80baxwgc	2	2	-	-	HYPH
cord-285778-80baxwgc	2	3	80baxwgc	80baxwgc	CD
cord-285778-80baxwgc	2	4	authors	author	NNS
cord-285778-80baxwgc	2	5	:	:	:
cord-285778-80baxwgc	3	1	nan	nan	NNP
cord-285778-80baxwgc	3	2	title	title	NN
cord-285778-80baxwgc	3	3	:	:	:
cord-285778-80baxwgc	3	4	Introduction	introduction	NN
cord-285778-80baxwgc	3	5	to	to	IN
cord-285778-80baxwgc	3	6	the	the	DT
cord-285778-80baxwgc	3	7	Immune	Immune	NNP
cord-285778-80baxwgc	3	8	Response	Response	NNP
cord-285778-80baxwgc	3	9	date	date	NN
cord-285778-80baxwgc	3	10	:	:	:
cord-285778-80baxwgc	3	11	2014	2014	CD
cord-285778-80baxwgc	3	12	-	-	SYM
cord-285778-80baxwgc	3	13	10	10	CD
cord-285778-80baxwgc	3	14	-	-	SYM
cord-285778-80baxwgc	3	15	10	10	CD
cord-285778-80baxwgc	3	16	journal	journal	NN
cord-285778-80baxwgc	3	17	:	:	:
cord-285778-80baxwgc	3	18	Primer	primer	NN
cord-285778-80baxwgc	3	19	to	to	IN
cord-285778-80baxwgc	3	20	the	the	DT
cord-285778-80baxwgc	3	21	Immune	Immune	NNP
cord-285778-80baxwgc	3	22	Response	response	NN
cord-285778-80baxwgc	4	1	DOI	DOI	NNP
cord-285778-80baxwgc	4	2	:	:	:
cord-285778-80baxwgc	5	1	10.1016	10.1016	CD
cord-285778-80baxwgc	5	2	/	/	SYM
cord-285778-80baxwgc	5	3	b978	b978	NN
cord-285778-80baxwgc	5	4	-	-	HYPH
cord-285778-80baxwgc	5	5	0	0	CD
cord-285778-80baxwgc	5	6	-	-	HYPH
cord-285778-80baxwgc	5	7	12	12	CD
cord-285778-80baxwgc	5	8	-	-	HYPH
cord-285778-80baxwgc	5	9	385245	385245	CD
cord-285778-80baxwgc	5	10	-	-	HYPH
cord-285778-80baxwgc	5	11	8.00001	8.00001	CD
cord-285778-80baxwgc	5	12	-	-	SYM
cord-285778-80baxwgc	5	13	7	7	CD
cord-285778-80baxwgc	5	14	sha	sha	NN
cord-285778-80baxwgc	5	15	:	:	:
cord-285778-80baxwgc	6	1	6efbfa215a506d5fbc448dbbf82dcb4661b38149	6efbfa215a506d5fbc448dbbf82dcb4661b38149	JJ
cord-285778-80baxwgc	7	1	doc_id	doc_id	CD
cord-285778-80baxwgc	7	2	:	:	:
cord-285778-80baxwgc	7	3	285778	285778	CD
cord-285778-80baxwgc	7	4	cord_uid	cord_uid	NNS
cord-285778-80baxwgc	7	5	:	:	:
cord-285778-80baxwgc	8	1	80baxwgc	80baxwgc	CD
cord-285778-80baxwgc	9	1	In	in	IN
cord-285778-80baxwgc	9	2	this	this	DT
cord-285778-80baxwgc	9	3	chapter	chapter	NN
cord-285778-80baxwgc	9	4	we	-PRON-	PRP
cord-285778-80baxwgc	9	5	provide	provide	VBP
cord-285778-80baxwgc	9	6	an	an	DT
cord-285778-80baxwgc	9	7	overview	overview	NN
cord-285778-80baxwgc	9	8	of	of	IN
cord-285778-80baxwgc	9	9	the	the	DT
cord-285778-80baxwgc	9	10	immune	immune	JJ
cord-285778-80baxwgc	9	11	system	system	NN
cord-285778-80baxwgc	9	12	and	and	CC
cord-285778-80baxwgc	9	13	its	-PRON-	PRP$
cord-285778-80baxwgc	9	14	vital	vital	JJ
cord-285778-80baxwgc	9	15	role	role	NN
cord-285778-80baxwgc	9	16	maintaining	maintain	VBG
cord-285778-80baxwgc	9	17	human	human	JJ
cord-285778-80baxwgc	9	18	health	health	NN
cord-285778-80baxwgc	9	19	.	.	.
cord-285778-80baxwgc	10	1	Immune	immune	JJ
cord-285778-80baxwgc	10	2	responses	response	NNS
cord-285778-80baxwgc	10	3	require	require	VBP
cord-285778-80baxwgc	10	4	the	the	DT
cord-285778-80baxwgc	10	5	coordinated	coordinated	JJ
cord-285778-80baxwgc	10	6	action	action	NN
cord-285778-80baxwgc	10	7	of	of	IN
cord-285778-80baxwgc	10	8	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	10	9	that	that	WDT
cord-285778-80baxwgc	10	10	travel	travel	VBP
cord-285778-80baxwgc	10	11	the	the	DT
cord-285778-80baxwgc	10	12	body	body	NN
cord-285778-80baxwgc	10	13	to	to	TO
cord-285778-80baxwgc	10	14	eliminate	eliminate	VB
cord-285778-80baxwgc	10	15	threats	threat	NNS
cord-285778-80baxwgc	10	16	posed	pose	VBN
cord-285778-80baxwgc	10	17	by	by	IN
cord-285778-80baxwgc	10	18	trauma	trauma	NN
cord-285778-80baxwgc	10	19	,	,	,
cord-285778-80baxwgc	10	20	infection	infection	NN
cord-285778-80baxwgc	10	21	,	,	,
cord-285778-80baxwgc	10	22	toxins	toxin	NNS
cord-285778-80baxwgc	10	23	,	,	,
cord-285778-80baxwgc	10	24	and	and	CC
cord-285778-80baxwgc	10	25	cancer	cancer	NN
cord-285778-80baxwgc	10	26	.	.	.
cord-285778-80baxwgc	11	1	Leukocytes	leukocyte	NNS
cord-285778-80baxwgc	11	2	communicate	communicate	VBP
cord-285778-80baxwgc	11	3	via	via	IN
cord-285778-80baxwgc	11	4	direct	direct	JJ
cord-285778-80baxwgc	11	5	contact	contact	NN
cord-285778-80baxwgc	11	6	and	and	CC
cord-285778-80baxwgc	11	7	via	via	IN
cord-285778-80baxwgc	11	8	production	production	NN
cord-285778-80baxwgc	11	9	and	and	CC
cord-285778-80baxwgc	11	10	receipt	receipt	NN
cord-285778-80baxwgc	11	11	of	of	IN
cord-285778-80baxwgc	11	12	soluble	soluble	JJ
cord-285778-80baxwgc	11	13	proteins	protein	NNS
cord-285778-80baxwgc	11	14	and	and	CC
cord-285778-80baxwgc	11	15	intercellular	intercellular	JJ
cord-285778-80baxwgc	11	16	messenger	messenger	NN
cord-285778-80baxwgc	11	17	proteins	protein	NNS
cord-285778-80baxwgc	11	18	called	call	VBD
cord-285778-80baxwgc	11	19	cytokines	cytokine	NNS
cord-285778-80baxwgc	11	20	.	.	.
cord-285778-80baxwgc	12	1	Complete	complete	JJ
cord-285778-80baxwgc	12	2	clearance	clearance	NN
cord-285778-80baxwgc	12	3	of	of	IN
cord-285778-80baxwgc	12	4	unwanted	unwanted	JJ
cord-285778-80baxwgc	12	5	entities	entity	NNS
cord-285778-80baxwgc	12	6	may	may	MD
cord-285778-80baxwgc	12	7	involve	involve	VB
cord-285778-80baxwgc	12	8	both	both	DT
cord-285778-80baxwgc	12	9	innate	innate	JJ
cord-285778-80baxwgc	12	10	and	and	CC
cord-285778-80baxwgc	12	11	adaptive	adaptive	JJ
cord-285778-80baxwgc	12	12	leukocyte	leukocyte	NN
cord-285778-80baxwgc	12	13	responses	response	NNS
cord-285778-80baxwgc	12	14	,	,	,
cord-285778-80baxwgc	12	15	which	which	WDT
cord-285778-80baxwgc	12	16	influence	influence	VBP
cord-285778-80baxwgc	12	17	each	each	DT
cord-285778-80baxwgc	12	18	other	other	JJ
cord-285778-80baxwgc	12	19	.	.	.
cord-285778-80baxwgc	13	1	Some	some	DT
cord-285778-80baxwgc	13	2	innate	innate	JJ
cord-285778-80baxwgc	13	3	mechanisms	mechanism	NNS
cord-285778-80baxwgc	13	4	require	require	VBP
cord-285778-80baxwgc	13	5	no	no	DT
cord-285778-80baxwgc	13	6	induction	induction	NN
cord-285778-80baxwgc	13	7	and	and	CC
cord-285778-80baxwgc	13	8	are	be	VBP
cord-285778-80baxwgc	13	9	completely	completely	RB
cord-285778-80baxwgc	13	10	non	non	JJ
cord-285778-80baxwgc	13	11	-	-	JJ
cord-285778-80baxwgc	13	12	specific	specific	JJ
cord-285778-80baxwgc	13	13	,	,	,
cord-285778-80baxwgc	13	14	whereas	whereas	IN
cord-285778-80baxwgc	13	15	others	other	NNS
cord-285778-80baxwgc	13	16	are	be	VBP
cord-285778-80baxwgc	13	17	inducible	inducible	JJ
cord-285778-80baxwgc	13	18	and	and	CC
cord-285778-80baxwgc	13	19	involve	involve	VBP
cord-285778-80baxwgc	13	20	broad	broad	JJ
cord-285778-80baxwgc	13	21	receptor	receptor	NN
cord-285778-80baxwgc	13	22	-	-	HYPH
cord-285778-80baxwgc	13	23	mediated	mediate	VBN
cord-285778-80baxwgc	13	24	recognition	recognition	NN
cord-285778-80baxwgc	13	25	of	of	IN
cord-285778-80baxwgc	13	26	a	a	DT
cord-285778-80baxwgc	13	27	limited	limited	JJ
cord-285778-80baxwgc	13	28	number	number	NN
cord-285778-80baxwgc	13	29	of	of	IN
cord-285778-80baxwgc	13	30	pathogen	pathogen	NN
cord-285778-80baxwgc	13	31	-	-	HYPH
cord-285778-80baxwgc	13	32	associated	associate	VBN
cord-285778-80baxwgc	13	33	or	or	CC
cord-285778-80baxwgc	13	34	damage	damage	NN
cord-285778-80baxwgc	13	35	-	-	HYPH
cord-285778-80baxwgc	13	36	associated	associate	VBN
cord-285778-80baxwgc	13	37	molecular	molecular	JJ
cord-285778-80baxwgc	13	38	patterns	pattern	NNS
cord-285778-80baxwgc	13	39	(	(	-LRB-
cord-285778-80baxwgc	13	40	PAMPs	pamp	NNS
cord-285778-80baxwgc	13	41	/	/	SYM
cord-285778-80baxwgc	13	42	DAMPs	damp	NNS
cord-285778-80baxwgc	13	43	)	)	-RRB-
cord-285778-80baxwgc	13	44	.	.	.
cord-285778-80baxwgc	14	1	Adaptive	adaptive	JJ
cord-285778-80baxwgc	14	2	responses	response	NNS
cord-285778-80baxwgc	14	3	involve	involve	VBP
cord-285778-80baxwgc	14	4	the	the	DT
cord-285778-80baxwgc	14	5	selective	selective	JJ
cord-285778-80baxwgc	14	6	activation	activation	NN
cord-285778-80baxwgc	14	7	of	of	IN
cord-285778-80baxwgc	14	8	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	14	9	via	via	IN
cord-285778-80baxwgc	14	10	engagement	engagement	NN
cord-285778-80baxwgc	14	11	of	of	IN
cord-285778-80baxwgc	14	12	their	-PRON-	PRP$
cord-285778-80baxwgc	14	13	antigen	antigen	NN
cord-285778-80baxwgc	14	14	receptors	receptor	NNS
cord-285778-80baxwgc	14	15	by	by	IN
cord-285778-80baxwgc	14	16	a	a	DT
cord-285778-80baxwgc	14	17	specific	specific	JJ
cord-285778-80baxwgc	14	18	foreign	foreign	JJ
cord-285778-80baxwgc	14	19	antigen	antigen	NN
cord-285778-80baxwgc	14	20	.	.	.
cord-285778-80baxwgc	15	1	The	the	DT
cord-285778-80baxwgc	15	2	three	three	CD
cord-285778-80baxwgc	15	3	major	major	JJ
cord-285778-80baxwgc	15	4	subsets	subset	NNS
cord-285778-80baxwgc	15	5	of	of	IN
cord-285778-80baxwgc	15	6	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	15	7	are	be	VBP
cord-285778-80baxwgc	15	8	T	T	NNP
cord-285778-80baxwgc	15	9	helper	helper	NN
cord-285778-80baxwgc	15	10	cells	cell	NNS
cord-285778-80baxwgc	15	11	(	(	-LRB-
cord-285778-80baxwgc	15	12	Th	Th	NNP
cord-285778-80baxwgc	15	13	)	)	-RRB-
cord-285778-80baxwgc	15	14	,	,	,
cord-285778-80baxwgc	15	15	cytotoxic	cytotoxic	JJ
cord-285778-80baxwgc	15	16	T	t	NN
cord-285778-80baxwgc	15	17	cells	cell	NNS
cord-285778-80baxwgc	15	18	(	(	-LRB-
cord-285778-80baxwgc	15	19	Tc	Tc	NNP
cord-285778-80baxwgc	15	20	)	)	-RRB-
cord-285778-80baxwgc	15	21	and	and	CC
cord-285778-80baxwgc	15	22	B	b	NN
cord-285778-80baxwgc	15	23	cells	cell	NNS
cord-285778-80baxwgc	15	24	,	,	,
cord-285778-80baxwgc	15	25	which	which	WDT
cord-285778-80baxwgc	15	26	use	use	VBP
cord-285778-80baxwgc	15	27	distinct	distinct	JJ
cord-285778-80baxwgc	15	28	mechanisms	mechanism	NNS
cord-285778-80baxwgc	15	29	to	to	TO
cord-285778-80baxwgc	15	30	recognize	recognize	VB
cord-285778-80baxwgc	15	31	antigen	antigen	NN
cord-285778-80baxwgc	15	32	and	and	CC
cord-285778-80baxwgc	15	33	carry	carry	VB
cord-285778-80baxwgc	15	34	out	out	RP
cord-285778-80baxwgc	15	35	different	different	JJ
cord-285778-80baxwgc	15	36	effector	effector	NN
cord-285778-80baxwgc	15	37	functions	function	NNS
cord-285778-80baxwgc	15	38	.	.	.
cord-285778-80baxwgc	16	1	Immune	immune	JJ
cord-285778-80baxwgc	16	2	system	system	NN
cord-285778-80baxwgc	16	3	malfunction	malfunction	NN
cord-285778-80baxwgc	16	4	can	can	MD
cord-285778-80baxwgc	16	5	contribute	contribute	VB
cord-285778-80baxwgc	16	6	to	to	IN
cord-285778-80baxwgc	16	7	many	many	JJ
cord-285778-80baxwgc	16	8	clinical	clinical	JJ
cord-285778-80baxwgc	16	9	illnesses	illness	NNS
cord-285778-80baxwgc	16	10	including	include	VBG
cord-285778-80baxwgc	16	11	autoimmune	autoimmune	JJ
cord-285778-80baxwgc	16	12	disorders	disorder	NNS
cord-285778-80baxwgc	16	13	,	,	,
cord-285778-80baxwgc	16	14	allergies	allergy	NNS
cord-285778-80baxwgc	16	15	,	,	,
cord-285778-80baxwgc	16	16	immunodeficiencies	immunodeficiency	NNS
cord-285778-80baxwgc	16	17	,	,	,
cord-285778-80baxwgc	16	18	chronic	chronic	JJ
cord-285778-80baxwgc	16	19	inflammation	inflammation	NN
cord-285778-80baxwgc	16	20	and	and	CC
cord-285778-80baxwgc	16	21	cancer	cancer	NN
cord-285778-80baxwgc	16	22	.	.	.
cord-285778-80baxwgc	17	1	stated	state	VBD
cord-285778-80baxwgc	17	2	that	that	IN
cord-285778-80baxwgc	17	3	microbes	microbe	NNS
cord-285778-80baxwgc	17	4	invisible	invisible	JJ
cord-285778-80baxwgc	17	5	to	to	IN
cord-285778-80baxwgc	17	6	the	the	DT
cord-285778-80baxwgc	17	7	naked	naked	JJ
cord-285778-80baxwgc	17	8	eye	eye	NN
cord-285778-80baxwgc	17	9	were	be	VBD
cord-285778-80baxwgc	17	10	responsible	responsible	JJ
cord-285778-80baxwgc	17	11	for	for	IN
cord-285778-80baxwgc	17	12	specific	specific	JJ
cord-285778-80baxwgc	17	13	illnesses	illness	NNS
cord-285778-80baxwgc	17	14	,	,	,
cord-285778-80baxwgc	17	15	and	and	CC
cord-285778-80baxwgc	17	16	the	the	DT
cord-285778-80baxwgc	17	17	first	first	JJ
cord-285778-80baxwgc	17	18	human	human	JJ
cord-285778-80baxwgc	17	19	disease	disease	NN
cord-285778-80baxwgc	17	20	-	-	HYPH
cord-285778-80baxwgc	17	21	causing	cause	VBG
cord-285778-80baxwgc	17	22	organisms	organism	NNS
cord-285778-80baxwgc	17	23	or	or	CC
cord-285778-80baxwgc	17	24	pathogens	pathogen	NNS
cord-285778-80baxwgc	17	25	were	be	VBD
cord-285778-80baxwgc	17	26	identified	identify	VBN
cord-285778-80baxwgc	17	27	in	in	IN
cord-285778-80baxwgc	17	28	the	the	DT
cord-285778-80baxwgc	17	29	late	late	JJ
cord-285778-80baxwgc	17	30	1800s	1800	NNS
cord-285778-80baxwgc	17	31	.	.	.
cord-285778-80baxwgc	18	1	At	at	IN
cord-285778-80baxwgc	18	2	about	about	RB
cord-285778-80baxwgc	18	3	the	the	DT
cord-285778-80baxwgc	18	4	same	same	JJ
cord-285778-80baxwgc	18	5	time	time	NN
cord-285778-80baxwgc	18	6	,	,	,
cord-285778-80baxwgc	18	7	Louis	Louis	NNP
cord-285778-80baxwgc	18	8	Pasteur	Pasteur	NNP
cord-285778-80baxwgc	18	9	applied	apply	VBD
cord-285778-80baxwgc	18	10	Jenner	Jenner	NNP
cord-285778-80baxwgc	18	11	's	's	POS
cord-285778-80baxwgc	18	12	immunization	immunization	NN
cord-285778-80baxwgc	18	13	technique	technique	NN
cord-285778-80baxwgc	18	14	for	for	IN
cord-285778-80baxwgc	18	15	smallpox	smallpox	NN
cord-285778-80baxwgc	18	16	to	to	IN
cord-285778-80baxwgc	18	17	the	the	DT
cord-285778-80baxwgc	18	18	prevention	prevention	NN
cord-285778-80baxwgc	18	19	of	of	IN
cord-285778-80baxwgc	18	20	various	various	JJ
cord-285778-80baxwgc	18	21	animal	animal	NN
cord-285778-80baxwgc	18	22	diseases	disease	NNS
cord-285778-80baxwgc	18	23	.	.	.
cord-285778-80baxwgc	19	1	Pasteur	Pasteur	NNP
cord-285778-80baxwgc	19	2	demonstrated	demonstrate	VBD
cord-285778-80baxwgc	19	3	that	that	IN
cord-285778-80baxwgc	19	4	inoculation	inoculation	NN
cord-285778-80baxwgc	19	5	with	with	IN
cord-285778-80baxwgc	19	6	a	a	DT
cord-285778-80baxwgc	19	7	pathogen	pathogen	NN
cord-285778-80baxwgc	19	8	that	that	WDT
cord-285778-80baxwgc	19	9	had	have	VBD
cord-285778-80baxwgc	19	10	been	be	VBN
cord-285778-80baxwgc	19	11	weakened	weaken	VBN
cord-285778-80baxwgc	19	12	in	in	IN
cord-285778-80baxwgc	19	13	the	the	DT
cord-285778-80baxwgc	19	14	laboratory	laboratory	NN
cord-285778-80baxwgc	19	15	could	could	MD
cord-285778-80baxwgc	19	16	protect	protect	VB
cord-285778-80baxwgc	19	17	against	against	IN
cord-285778-80baxwgc	19	18	a	a	DT
cord-285778-80baxwgc	19	19	subsequent	subsequent	JJ
cord-285778-80baxwgc	19	20	exposure	exposure	NN
cord-285778-80baxwgc	19	21	to	to	IN
cord-285778-80baxwgc	19	22	the	the	DT
cord-285778-80baxwgc	19	23	naturally	naturally	RB
cord-285778-80baxwgc	19	24	occurring	occur	VBG
cord-285778-80baxwgc	19	25	pathogen	pathogen	NN
cord-285778-80baxwgc	19	26	.	.	.
cord-285778-80baxwgc	20	1	It	-PRON-	PRP
cord-285778-80baxwgc	20	2	was	be	VBD
cord-285778-80baxwgc	20	3	Pasteur	Pasteur	NNP
cord-285778-80baxwgc	20	4	who	who	WP
cord-285778-80baxwgc	20	5	coined	coin	VBD
cord-285778-80baxwgc	20	6	the	the	DT
cord-285778-80baxwgc	20	7	term	term	NN
cord-285778-80baxwgc	20	8	vaccination	vaccination	NN
cord-285778-80baxwgc	20	9	(	(	-LRB-
cord-285778-80baxwgc	20	10	from	from	IN
cord-285778-80baxwgc	20	11	the	the	DT
cord-285778-80baxwgc	20	12	Latin	latin	JJ
cord-285778-80baxwgc	20	13	vaccinus	vaccinus	NN
cord-285778-80baxwgc	20	14	,	,	,
cord-285778-80baxwgc	20	15	meaning	mean	VBG
cord-285778-80baxwgc	20	16	"	"	``
cord-285778-80baxwgc	20	17	derived	derive	VBN
cord-285778-80baxwgc	20	18	from	from	IN
cord-285778-80baxwgc	20	19	cows	cow	NNS
cord-285778-80baxwgc	20	20	"	"	''
cord-285778-80baxwgc	20	21	)	)	-RRB-
cord-285778-80baxwgc	20	22	for	for	IN
cord-285778-80baxwgc	20	23	this	this	DT
cord-285778-80baxwgc	20	24	procedure	procedure	NN
cord-285778-80baxwgc	20	25	,	,	,
cord-285778-80baxwgc	20	26	in	in	IN
cord-285778-80baxwgc	20	27	honor	honor	NN
cord-285778-80baxwgc	20	28	of	of	IN
cord-285778-80baxwgc	20	29	Jenner	Jenner	NNP
cord-285778-80baxwgc	20	30	's	's	POS
cord-285778-80baxwgc	20	31	work	work	NN
cord-285778-80baxwgc	20	32	.	.	.
cord-285778-80baxwgc	21	1	The	the	DT
cord-285778-80baxwgc	21	2	research	research	NN
cord-285778-80baxwgc	21	3	of	of	IN
cord-285778-80baxwgc	21	4	Pasteur	Pasteur	NNP
cord-285778-80baxwgc	21	5	and	and	CC
cord-285778-80baxwgc	21	6	other	other	JJ
cord-285778-80baxwgc	21	7	investigators	investigator	NNS
cord-285778-80baxwgc	21	8	spurred	spur	VBD
cord-285778-80baxwgc	21	9	the	the	DT
cord-285778-80baxwgc	21	10	evolution	evolution	NN
cord-285778-80baxwgc	21	11	of	of	IN
cord-285778-80baxwgc	21	12	immunology	immunology	NN
cord-285778-80baxwgc	21	13	as	as	IN
cord-285778-80baxwgc	21	14	a	a	DT
cord-285778-80baxwgc	21	15	science	science	NN
cord-285778-80baxwgc	21	16	distinct	distinct	JJ
cord-285778-80baxwgc	21	17	from	from	IN
cord-285778-80baxwgc	21	18	(	(	-LRB-
cord-285778-80baxwgc	21	19	but	but	CC
cord-285778-80baxwgc	21	20	related	relate	VBN
cord-285778-80baxwgc	21	21	to	to	IN
cord-285778-80baxwgc	21	22	)	)	-RRB-
cord-285778-80baxwgc	21	23	the	the	DT
cord-285778-80baxwgc	21	24	established	establish	VBN
cord-285778-80baxwgc	21	25	fields	field	NNS
cord-285778-80baxwgc	21	26	of	of	IN
cord-285778-80baxwgc	21	27	microbiology	microbiology	NN
cord-285778-80baxwgc	21	28	,	,	,
cord-285778-80baxwgc	21	29	pathology	pathology	NN
cord-285778-80baxwgc	21	30	,	,	,
cord-285778-80baxwgc	21	31	biochemistry	biochemistry	NN
cord-285778-80baxwgc	21	32	and	and	CC
cord-285778-80baxwgc	21	33	histology	histology	NN
cord-285778-80baxwgc	21	34	.	.	.
cord-285778-80baxwgc	22	1	Today	today	NN
cord-285778-80baxwgc	22	2	,	,	,
cord-285778-80baxwgc	22	3	immunology	immunology	NN
cord-285778-80baxwgc	22	4	can	can	MD
cord-285778-80baxwgc	22	5	be	be	VB
cord-285778-80baxwgc	22	6	defined	define	VBN
cord-285778-80baxwgc	22	7	as	as	IN
cord-285778-80baxwgc	22	8	the	the	DT
cord-285778-80baxwgc	22	9	study	study	NN
cord-285778-80baxwgc	22	10	of	of	IN
cord-285778-80baxwgc	22	11	the	the	DT
cord-285778-80baxwgc	22	12	cells	cell	NNS
cord-285778-80baxwgc	22	13	and	and	CC
cord-285778-80baxwgc	22	14	tissues	tissue	NNS
cord-285778-80baxwgc	22	15	that	that	WDT
cord-285778-80baxwgc	22	16	mediate	mediate	VBP
cord-285778-80baxwgc	22	17	immunity	immunity	NN
cord-285778-80baxwgc	22	18	and	and	CC
cord-285778-80baxwgc	22	19	the	the	DT
cord-285778-80baxwgc	22	20	investigation	investigation	NN
cord-285778-80baxwgc	22	21	of	of	IN
cord-285778-80baxwgc	22	22	the	the	DT
cord-285778-80baxwgc	22	23	genes	gene	NNS
cord-285778-80baxwgc	22	24	and	and	CC
cord-285778-80baxwgc	22	25	proteins	protein	NNS
cord-285778-80baxwgc	22	26	underlying	underlie	VBG
cord-285778-80baxwgc	22	27	their	-PRON-	PRP$
cord-285778-80baxwgc	22	28	function	function	NN
cord-285778-80baxwgc	22	29	.	.	.
cord-285778-80baxwgc	23	1	A	a	DT
cord-285778-80baxwgc	23	2	normal	normal	JJ
cord-285778-80baxwgc	23	3	healthy	healthy	JJ
cord-285778-80baxwgc	23	4	person	person	NN
cord-285778-80baxwgc	23	5	's	's	POS
cord-285778-80baxwgc	23	6	body	body	NN
cord-285778-80baxwgc	23	7	always	always	RB
cord-285778-80baxwgc	23	8	strives	strive	VBZ
cord-285778-80baxwgc	23	9	to	to	TO
cord-285778-80baxwgc	23	10	maintain	maintain	VB
cord-285778-80baxwgc	23	11	homeostasis	homeostasis	NN
cord-285778-80baxwgc	23	12	,	,	,
cord-285778-80baxwgc	23	13	a	a	DT
cord-285778-80baxwgc	23	14	natural	natural	JJ
cord-285778-80baxwgc	23	15	state	state	NN
cord-285778-80baxwgc	23	16	of	of	IN
cord-285778-80baxwgc	23	17	balance	balance	NN
cord-285778-80baxwgc	23	18	of	of	IN
cord-285778-80baxwgc	23	19	all	all	PDT
cord-285778-80baxwgc	23	20	its	-PRON-	PRP$
cord-285778-80baxwgc	23	21	organs	organ	NNS
cord-285778-80baxwgc	23	22	and	and	CC
cord-285778-80baxwgc	23	23	the	the	DT
cord-285778-80baxwgc	23	24	nervous	nervous	JJ
cord-285778-80baxwgc	23	25	and	and	CC
cord-285778-80baxwgc	23	26	circulatory	circulatory	JJ
cord-285778-80baxwgc	23	27	systems	system	NNS
cord-285778-80baxwgc	23	28	.	.	.
cord-285778-80baxwgc	24	1	When	when	WRB
cord-285778-80baxwgc	24	2	this	this	DT
cord-285778-80baxwgc	24	3	homeostasis	homeostasis	NN
cord-285778-80baxwgc	24	4	is	be	VBZ
cord-285778-80baxwgc	24	5	disturbed	disturb	VBN
cord-285778-80baxwgc	24	6	by	by	IN
cord-285778-80baxwgc	24	7	either	either	DT
cord-285778-80baxwgc	24	8	trauma	trauma	NN
cord-285778-80baxwgc	24	9	,	,	,
cord-285778-80baxwgc	24	10	pathogens	pathogen	NNS
cord-285778-80baxwgc	24	11	,	,	,
cord-285778-80baxwgc	24	12	or	or	CC
cord-285778-80baxwgc	24	13	the	the	DT
cord-285778-80baxwgc	24	14	deregulation	deregulation	NN
cord-285778-80baxwgc	24	15	of	of	IN
cord-285778-80baxwgc	24	16	body	body	NN
cord-285778-80baxwgc	24	17	cells	cell	NNS
cord-285778-80baxwgc	24	18	(	(	-LRB-
cord-285778-80baxwgc	24	19	such	such	JJ
cord-285778-80baxwgc	24	20	occurs	occur	VBZ
cord-285778-80baxwgc	24	21	in	in	IN
cord-285778-80baxwgc	24	22	cancer	cancer	NN
cord-285778-80baxwgc	24	23	)	)	-RRB-
cord-285778-80baxwgc	24	24	,	,	,
cord-285778-80baxwgc	24	25	the	the	DT
cord-285778-80baxwgc	24	26	immune	immune	JJ
cord-285778-80baxwgc	24	27	system	system	NN
cord-285778-80baxwgc	24	28	responds	respond	VBZ
cord-285778-80baxwgc	24	29	in	in	IN
cord-285778-80baxwgc	24	30	an	an	DT
cord-285778-80baxwgc	24	31	attempt	attempt	NN
cord-285778-80baxwgc	24	32	to	to	TO
cord-285778-80baxwgc	24	33	restore	restore	VB
cord-285778-80baxwgc	24	34	balance	balance	NN
cord-285778-80baxwgc	24	35	.	.	.
cord-285778-80baxwgc	25	1	At	at	IN
cord-285778-80baxwgc	25	2	its	-PRON-	PRP$
cord-285778-80baxwgc	25	3	simplest	simple	JJS
cord-285778-80baxwgc	25	4	level	level	NN
cord-285778-80baxwgc	25	5	,	,	,
cord-285778-80baxwgc	25	6	this	this	DT
cord-285778-80baxwgc	25	7	response	response	NN
cord-285778-80baxwgc	25	8	involves	involve	VBZ
cord-285778-80baxwgc	25	9	identifying	identify	VBG
cord-285778-80baxwgc	25	10	and	and	CC
cord-285778-80baxwgc	25	11	clearing	clear	VBG
cord-285778-80baxwgc	25	12	damaged	damage	VBN
cord-285778-80baxwgc	25	13	and	and	CC
cord-285778-80baxwgc	25	14	dying	die	VBG
cord-285778-80baxwgc	25	15	cells	cell	NNS
cord-285778-80baxwgc	25	16	from	from	IN
cord-285778-80baxwgc	25	17	the	the	DT
cord-285778-80baxwgc	25	18	body	body	NN
cord-285778-80baxwgc	25	19	.	.	.
cord-285778-80baxwgc	26	1	More	More	JJR
cord-285778-80baxwgc	26	2	complex	complex	JJ
cord-285778-80baxwgc	26	3	responses	response	NNS
cord-285778-80baxwgc	26	4	have	have	VBP
cord-285778-80baxwgc	26	5	evolved	evolve	VBN
cord-285778-80baxwgc	26	6	to	to	TO
cord-285778-80baxwgc	26	7	counteract	counteract	VB
cord-285778-80baxwgc	26	8	assault	assault	NN
cord-285778-80baxwgc	26	9	on	on	IN
cord-285778-80baxwgc	26	10	Selected	selected	JJ
cord-285778-80baxwgc	26	11	landmark	landmark	NN
cord-285778-80baxwgc	26	12	discoveries	discovery	NNS
cord-285778-80baxwgc	26	13	in	in	IN
cord-285778-80baxwgc	26	14	immunology	immunology	NN
cord-285778-80baxwgc	26	15	and	and	CC
cord-285778-80baxwgc	26	16	immunologists	immunologist	NNS
cord-285778-80baxwgc	26	17	who	who	WP
cord-285778-80baxwgc	26	18	have	have	VBP
cord-285778-80baxwgc	26	19	won	win	VBN
cord-285778-80baxwgc	26	20	Nobel	Nobel	NNP
cord-285778-80baxwgc	26	21	Prizes	Prizes	NNP
cord-285778-80baxwgc	26	22	for	for	IN
cord-285778-80baxwgc	26	23	their	-PRON-	PRP$
cord-285778-80baxwgc	26	24	work	work	NN
cord-285778-80baxwgc	26	25	are	be	VBP
cord-285778-80baxwgc	26	26	featured	feature	VBN
cord-285778-80baxwgc	26	27	in	in	IN
cord-285778-80baxwgc	26	28	Appendices	Appendices	NNPS
cord-285778-80baxwgc	26	29	A	A	NNP
cord-285778-80baxwgc	26	30	and	and	CC
cord-285778-80baxwgc	26	31	B	b	NN
cord-285778-80baxwgc	26	32	,	,	,
cord-285778-80baxwgc	26	33	respectively	respectively	RB
cord-285778-80baxwgc	26	34	.	.	.
cord-285778-80baxwgc	27	1	the	the	DT
cord-285778-80baxwgc	27	2	body	body	NN
cord-285778-80baxwgc	27	3	by	by	IN
cord-285778-80baxwgc	27	4	infectious	infectious	JJ
cord-285778-80baxwgc	27	5	agents	agent	NNS
cord-285778-80baxwgc	27	6	,	,	,
cord-285778-80baxwgc	27	7	including	include	VBG
cord-285778-80baxwgc	27	8	bacteria	bacteria	NNS
cord-285778-80baxwgc	27	9	,	,	,
cord-285778-80baxwgc	27	10	viruses	virus	NNS
cord-285778-80baxwgc	27	11	,	,	,
cord-285778-80baxwgc	27	12	parasites	parasite	NNS
cord-285778-80baxwgc	27	13	and	and	CC
cord-285778-80baxwgc	27	14	fungi	fungus	NNS
cord-285778-80baxwgc	27	15	.	.	.
cord-285778-80baxwgc	28	1	Because	because	IN
cord-285778-80baxwgc	28	2	these	these	DT
cord-285778-80baxwgc	28	3	foreign	foreign	JJ
cord-285778-80baxwgc	28	4	invaders	invader	NNS
cord-285778-80baxwgc	28	5	are	be	VBP
cord-285778-80baxwgc	28	6	literally	literally	RB
cord-285778-80baxwgc	28	7	everywhere	everywhere	RB
cord-285778-80baxwgc	28	8	on	on	IN
cord-285778-80baxwgc	28	9	Earth	Earth	NNP
cord-285778-80baxwgc	28	10	and	and	CC
cord-285778-80baxwgc	28	11	constantly	constantly	RB
cord-285778-80baxwgc	28	12	seeking	seek	VBG
cord-285778-80baxwgc	28	13	vulnerable	vulnerable	JJ
cord-285778-80baxwgc	28	14	hosts	host	NNS
cord-285778-80baxwgc	28	15	,	,	,
cord-285778-80baxwgc	28	16	the	the	DT
cord-285778-80baxwgc	28	17	immune	immune	JJ
cord-285778-80baxwgc	28	18	system	system	NN
cord-285778-80baxwgc	28	19	is	be	VBZ
cord-285778-80baxwgc	28	20	constantly	constantly	RB
cord-285778-80baxwgc	28	21	occupied	occupy	VBN
cord-285778-80baxwgc	28	22	with	with	IN
cord-285778-80baxwgc	28	23	containing	contain	VBG
cord-285778-80baxwgc	28	24	attacks	attack	NNS
cord-285778-80baxwgc	28	25	from	from	IN
cord-285778-80baxwgc	28	26	this	this	DT
cord-285778-80baxwgc	28	27	quarter	quarter	NN
cord-285778-80baxwgc	28	28	.	.	.
cord-285778-80baxwgc	29	1	Indeed	indeed	RB
cord-285778-80baxwgc	29	2	,	,	,
cord-285778-80baxwgc	29	3	despite	despite	IN
cord-285778-80baxwgc	29	4	the	the	DT
cord-285778-80baxwgc	29	5	successful	successful	JJ
cord-285778-80baxwgc	29	6	eradication	eradication	NN
cord-285778-80baxwgc	29	7	of	of	IN
cord-285778-80baxwgc	29	8	smallpox	smallpox	NN
cord-285778-80baxwgc	29	9	and	and	CC
cord-285778-80baxwgc	29	10	the	the	DT
cord-285778-80baxwgc	29	11	development	development	NN
cord-285778-80baxwgc	29	12	of	of	IN
cord-285778-80baxwgc	29	13	antibiotics	antibiotic	NNS
cord-285778-80baxwgc	29	14	,	,	,
cord-285778-80baxwgc	29	15	infectious	infectious	JJ
cord-285778-80baxwgc	29	16	diseases	disease	NNS
cord-285778-80baxwgc	29	17	remain	remain	VBP
cord-285778-80baxwgc	29	18	among	among	IN
cord-285778-80baxwgc	29	19	the	the	DT
cord-285778-80baxwgc	29	20	biggest	big	JJS
cord-285778-80baxwgc	29	21	killers	killer	NNS
cord-285778-80baxwgc	29	22	on	on	IN
cord-285778-80baxwgc	29	23	the	the	DT
cord-285778-80baxwgc	29	24	planet	planet	NN
cord-285778-80baxwgc	29	25	.	.	.
cord-285778-80baxwgc	30	1	Longstanding	longstanding	JJ
cord-285778-80baxwgc	30	2	disorders	disorder	NNS
cord-285778-80baxwgc	30	3	such	such	JJ
cord-285778-80baxwgc	30	4	as	as	IN
cord-285778-80baxwgc	30	5	malaria	malaria	NN
cord-285778-80baxwgc	30	6	and	and	CC
cord-285778-80baxwgc	30	7	tuberculosis	tuberculosis	NN
cord-285778-80baxwgc	30	8	,	,	,
cord-285778-80baxwgc	30	9	as	as	RB
cord-285778-80baxwgc	30	10	well	well	RB
cord-285778-80baxwgc	30	11	as	as	IN
cord-285778-80baxwgc	30	12	"	"	``
cord-285778-80baxwgc	30	13	emerging	emerge	VBG
cord-285778-80baxwgc	30	14	"	"	''
cord-285778-80baxwgc	30	15	diseases	disease	NNS
cord-285778-80baxwgc	30	16	caused	cause	VBN
cord-285778-80baxwgc	30	17	by	by	IN
cord-285778-80baxwgc	30	18	new	new	JJ
cord-285778-80baxwgc	30	19	pathogens	pathogen	NNS
cord-285778-80baxwgc	30	20	such	such	JJ
cord-285778-80baxwgc	30	21	as	as	IN
cord-285778-80baxwgc	30	22	West	West	NNP
cord-285778-80baxwgc	30	23	Nile	Nile	NNP
cord-285778-80baxwgc	30	24	virus	virus	NN
cord-285778-80baxwgc	30	25	,	,	,
cord-285778-80baxwgc	30	26	severe	severe	JJ
cord-285778-80baxwgc	30	27	acute	acute	JJ
cord-285778-80baxwgc	30	28	respiratory	respiratory	JJ
cord-285778-80baxwgc	30	29	syndrome	syndrome	NN
cord-285778-80baxwgc	30	30	(	(	-LRB-
cord-285778-80baxwgc	30	31	SARS	SARS	NNP
cord-285778-80baxwgc	30	32	)	)	-RRB-
cord-285778-80baxwgc	30	33	virus	virus	NN
cord-285778-80baxwgc	30	34	,	,	,
cord-285778-80baxwgc	30	35	and	and	CC
cord-285778-80baxwgc	30	36	H1N1	H1N1	NNP
cord-285778-80baxwgc	30	37	influenza	influenza	NN
cord-285778-80baxwgc	30	38	virus	virus	NN
cord-285778-80baxwgc	30	39	,	,	,
cord-285778-80baxwgc	30	40	present	present	JJ
cord-285778-80baxwgc	30	41	ongoing	ongoing	JJ
cord-285778-80baxwgc	30	42	challenges	challenge	NNS
cord-285778-80baxwgc	30	43	to	to	IN
cord-285778-80baxwgc	30	44	the	the	DT
cord-285778-80baxwgc	30	45	immune	immune	JJ
cord-285778-80baxwgc	30	46	system	system	NN
cord-285778-80baxwgc	30	47	.	.	.
cord-285778-80baxwgc	31	1	Humans	human	NNS
cord-285778-80baxwgc	31	2	are	be	VBP
cord-285778-80baxwgc	31	3	surrounded	surround	VBN
cord-285778-80baxwgc	31	4	by	by	IN
cord-285778-80baxwgc	31	5	other	other	JJ
cord-285778-80baxwgc	31	6	organisms	organism	NNS
cord-285778-80baxwgc	31	7	-	-	:
cord-285778-80baxwgc	31	8	in	in	IN
cord-285778-80baxwgc	31	9	the	the	DT
cord-285778-80baxwgc	31	10	air	air	NN
cord-285778-80baxwgc	31	11	,	,	,
cord-285778-80baxwgc	31	12	in	in	IN
cord-285778-80baxwgc	31	13	the	the	DT
cord-285778-80baxwgc	31	14	soil	soil	NN
cord-285778-80baxwgc	31	15	,	,	,
cord-285778-80baxwgc	31	16	in	in	IN
cord-285778-80baxwgc	31	17	the	the	DT
cord-285778-80baxwgc	31	18	water	water	NN
cord-285778-80baxwgc	31	19	,	,	,
cord-285778-80baxwgc	31	20	on	on	IN
cord-285778-80baxwgc	31	21	the	the	DT
cord-285778-80baxwgc	31	22	skin	skin	NN
cord-285778-80baxwgc	31	23	,	,	,
cord-285778-80baxwgc	31	24	and	and	CC
cord-285778-80baxwgc	31	25	on	on	IN
cord-285778-80baxwgc	31	26	the	the	DT
cord-285778-80baxwgc	31	27	mucosae	mucosae	NNP
cord-285778-80baxwgc	31	28	,	,	,
cord-285778-80baxwgc	31	29	the	the	DT
cord-285778-80baxwgc	31	30	protective	protective	JJ
cord-285778-80baxwgc	31	31	layers	layer	NNS
cord-285778-80baxwgc	31	32	of	of	IN
cord-285778-80baxwgc	31	33	epithelial	epithelial	JJ
cord-285778-80baxwgc	31	34	cells	cell	NNS
cord-285778-80baxwgc	31	35	that	that	WDT
cord-285778-80baxwgc	31	36	line	line	VBP
cord-285778-80baxwgc	31	37	the	the	DT
cord-285778-80baxwgc	31	38	gastrointestinal	gastrointestinal	JJ
cord-285778-80baxwgc	31	39	,	,	,
cord-285778-80baxwgc	31	40	urogenital	urogenital	JJ
cord-285778-80baxwgc	31	41	and	and	CC
cord-285778-80baxwgc	31	42	respiratory	respiratory	JJ
cord-285778-80baxwgc	31	43	tracts	tract	NNS
cord-285778-80baxwgc	31	44	.	.	.
cord-285778-80baxwgc	32	1	While	while	IN
cord-285778-80baxwgc	32	2	most	most	JJS
cord-285778-80baxwgc	32	3	of	of	IN
cord-285778-80baxwgc	32	4	these	these	DT
cord-285778-80baxwgc	32	5	organisms	organism	NNS
cord-285778-80baxwgc	32	6	are	be	VBP
cord-285778-80baxwgc	32	7	harmless	harmless	JJ
cord-285778-80baxwgc	32	8	and	and	CC
cord-285778-80baxwgc	32	9	some	some	DT
cord-285778-80baxwgc	32	10	are	be	VBP
cord-285778-80baxwgc	32	11	even	even	RB
cord-285778-80baxwgc	32	12	beneficial	beneficial	JJ
cord-285778-80baxwgc	32	13	,	,	,
cord-285778-80baxwgc	32	14	some	some	DT
cord-285778-80baxwgc	32	15	are	be	VBP
cord-285778-80baxwgc	32	16	pathogenic	pathogenic	JJ
cord-285778-80baxwgc	32	17	.	.	.
cord-285778-80baxwgc	33	1	Like	like	IN
cord-285778-80baxwgc	33	2	all	all	DT
cord-285778-80baxwgc	33	3	species	specie	NNS
cord-285778-80baxwgc	33	4	,	,	,
cord-285778-80baxwgc	33	5	pathogens	pathogen	NNS
cord-285778-80baxwgc	33	6	live	live	VBP
cord-285778-80baxwgc	33	7	to	to	TO
cord-285778-80baxwgc	33	8	reproduce	reproduce	VB
cord-285778-80baxwgc	33	9	.	.	.
cord-285778-80baxwgc	34	1	In	in	IN
cord-285778-80baxwgc	34	2	order	order	NN
cord-285778-80baxwgc	34	3	to	to	TO
cord-285778-80baxwgc	34	4	reproduce	reproduce	VB
cord-285778-80baxwgc	34	5	,	,	,
cord-285778-80baxwgc	34	6	however	however	RB
cord-285778-80baxwgc	34	7	,	,	,
cord-285778-80baxwgc	34	8	many	many	JJ
cord-285778-80baxwgc	34	9	must	must	MD
cord-285778-80baxwgc	34	10	penetrate	penetrate	VB
cord-285778-80baxwgc	34	11	a	a	DT
cord-285778-80baxwgc	34	12	host	host	NN
cord-285778-80baxwgc	34	13	's	's	POS
cord-285778-80baxwgc	34	14	body	body	NN
cord-285778-80baxwgc	34	15	or	or	CC
cord-285778-80baxwgc	34	16	one	one	CD
cord-285778-80baxwgc	34	17	of	of	IN
cord-285778-80baxwgc	34	18	its	-PRON-	PRP$
cord-285778-80baxwgc	34	19	component	component	NN
cord-285778-80baxwgc	34	20	cells	cell	NNS
cord-285778-80baxwgc	34	21	.	.	.
cord-285778-80baxwgc	35	1	Infection	infection	NN
cord-285778-80baxwgc	35	2	is	be	VBZ
cord-285778-80baxwgc	35	3	defined	define	VBN
cord-285778-80baxwgc	35	4	as	as	IN
cord-285778-80baxwgc	35	5	the	the	DT
cord-285778-80baxwgc	35	6	attachment	attachment	NN
cord-285778-80baxwgc	35	7	and	and	CC
cord-285778-80baxwgc	35	8	entry	entry	NN
cord-285778-80baxwgc	35	9	of	of	IN
cord-285778-80baxwgc	35	10	a	a	DT
cord-285778-80baxwgc	35	11	pathogen	pathogen	NN
cord-285778-80baxwgc	35	12	into	into	IN
cord-285778-80baxwgc	35	13	the	the	DT
cord-285778-80baxwgc	35	14	host	host	NN
cord-285778-80baxwgc	35	15	.	.	.
cord-285778-80baxwgc	36	1	Once	once	IN
cord-285778-80baxwgc	36	2	inside	inside	IN
cord-285778-80baxwgc	36	3	the	the	DT
cord-285778-80baxwgc	36	4	body	body	NN
cord-285778-80baxwgc	36	5	or	or	CC
cord-285778-80baxwgc	36	6	cell	cell	NN
cord-285778-80baxwgc	36	7	,	,	,
cord-285778-80baxwgc	36	8	the	the	DT
cord-285778-80baxwgc	36	9	pathogen	pathogen	NN
cord-285778-80baxwgc	36	10	replicates	replicate	VBZ
cord-285778-80baxwgc	36	11	,	,	,
cord-285778-80baxwgc	36	12	generating	generate	VBG
cord-285778-80baxwgc	36	13	progeny	progeny	NN
cord-285778-80baxwgc	36	14	that	that	WDT
cord-285778-80baxwgc	36	15	spread	spread	VBD
cord-285778-80baxwgc	36	16	into	into	IN
cord-285778-80baxwgc	36	17	the	the	DT
cord-285778-80baxwgc	36	18	body	body	NN
cord-285778-80baxwgc	36	19	in	in	IN
cord-285778-80baxwgc	36	20	a	a	DT
cord-285778-80baxwgc	36	21	localized	localized	JJ
cord-285778-80baxwgc	36	22	or	or	CC
cord-285778-80baxwgc	36	23	systemic	systemic	JJ
cord-285778-80baxwgc	36	24	fashion	fashion	NN
cord-285778-80baxwgc	36	25	.	.	.
cord-285778-80baxwgc	37	1	The	the	DT
cord-285778-80baxwgc	37	2	manner	manner	NN
cord-285778-80baxwgc	37	3	of	of	IN
cord-285778-80baxwgc	37	4	this	this	DT
cord-285778-80baxwgc	37	5	replication	replication	NN
cord-285778-80baxwgc	37	6	determines	determine	VBZ
cord-285778-80baxwgc	37	7	whether	whether	IN
cord-285778-80baxwgc	37	8	the	the	DT
cord-285778-80baxwgc	37	9	pathogen	pathogen	NN
cord-285778-80baxwgc	37	10	is	be	VBZ
cord-285778-80baxwgc	37	11	considered	consider	VBN
cord-285778-80baxwgc	37	12	extracellular	extracellular	JJ
cord-285778-80baxwgc	37	13	or	or	CC
cord-285778-80baxwgc	37	14	intracellular	intracellular	JJ
cord-285778-80baxwgc	37	15	.	.	.
cord-285778-80baxwgc	38	1	Extracellular	Extracellular	NNP
cord-285778-80baxwgc	38	2	pathogens	pathogen	NNS
cord-285778-80baxwgc	38	3	,	,	,
cord-285778-80baxwgc	38	4	such	such	JJ
cord-285778-80baxwgc	38	5	as	as	IN
cord-285778-80baxwgc	38	6	certain	certain	JJ
cord-285778-80baxwgc	38	7	bacteria	bacteria	NNS
cord-285778-80baxwgc	38	8	and	and	CC
cord-285778-80baxwgc	38	9	parasites	parasite	NNS
cord-285778-80baxwgc	38	10	,	,	,
cord-285778-80baxwgc	38	11	do	do	VBP
cord-285778-80baxwgc	38	12	not	not	RB
cord-285778-80baxwgc	38	13	need	need	VB
cord-285778-80baxwgc	38	14	to	to	TO
cord-285778-80baxwgc	38	15	enter	enter	VB
cord-285778-80baxwgc	38	16	cells	cell	NNS
cord-285778-80baxwgc	38	17	to	to	TO
cord-285778-80baxwgc	38	18	reproduce	reproduce	VB
cord-285778-80baxwgc	38	19	.	.	.
cord-285778-80baxwgc	39	1	After	after	IN
cord-285778-80baxwgc	39	2	accessing	access	VBG
cord-285778-80baxwgc	39	3	the	the	DT
cord-285778-80baxwgc	39	4	body	body	NN
cord-285778-80baxwgc	39	5	,	,	,
cord-285778-80baxwgc	39	6	these	these	DT
cord-285778-80baxwgc	39	7	organisms	organism	NNS
cord-285778-80baxwgc	39	8	replicate	replicate	VBP
cord-285778-80baxwgc	39	9	first	first	RB
cord-285778-80baxwgc	39	10	in	in	IN
cord-285778-80baxwgc	39	11	the	the	DT
cord-285778-80baxwgc	39	12	interstitial	interstitial	JJ
cord-285778-80baxwgc	39	13	fluid	fluid	NN
cord-285778-80baxwgc	39	14	bathing	bathe	VBG
cord-285778-80baxwgc	39	15	the	the	DT
cord-285778-80baxwgc	39	16	tissues	tissue	NNS
cord-285778-80baxwgc	39	17	and	and	CC
cord-285778-80baxwgc	39	18	may	may	MD
cord-285778-80baxwgc	39	19	then	then	RB
cord-285778-80baxwgc	39	20	disseminate	disseminate	VB
cord-285778-80baxwgc	39	21	via	via	IN
cord-285778-80baxwgc	39	22	the	the	DT
cord-285778-80baxwgc	39	23	blood	blood	NN
cord-285778-80baxwgc	39	24	(	(	-LRB-
cord-285778-80baxwgc	39	25	Fig	Fig	NNP
cord-285778-80baxwgc	39	26	.	.	.
cord-285778-80baxwgc	39	27	1	1	CD
cord-285778-80baxwgc	39	28	-	-	SYM
cord-285778-80baxwgc	39	29	1	1	CD
cord-285778-80baxwgc	39	30	)	)	-RRB-
cord-285778-80baxwgc	39	31	.	.	.
cord-285778-80baxwgc	40	1	Intracellular	Intracellular	NNP
cord-285778-80baxwgc	40	2	pathogens	pathogen	NNS
cord-285778-80baxwgc	40	3	,	,	,
cord-285778-80baxwgc	40	4	such	such	JJ
cord-285778-80baxwgc	40	5	as	as	IN
cord-285778-80baxwgc	40	6	viruses	virus	NNS
cord-285778-80baxwgc	40	7	and	and	CC
cord-285778-80baxwgc	40	8	other	other	JJ
cord-285778-80baxwgc	40	9	bacteria	bacteria	NNS
cord-285778-80baxwgc	40	10	and	and	CC
cord-285778-80baxwgc	40	11	parasites	parasite	NNS
cord-285778-80baxwgc	40	12	,	,	,
cord-285778-80baxwgc	40	13	enter	enter	VB
cord-285778-80baxwgc	40	14	a	a	DT
cord-285778-80baxwgc	40	15	host	host	NN
cord-285778-80baxwgc	40	16	cell	cell	NN
cord-285778-80baxwgc	40	17	,	,	,
cord-285778-80baxwgc	40	18	subvert	subvert	VB
cord-285778-80baxwgc	40	19	its	-PRON-	PRP$
cord-285778-80baxwgc	40	20	metabolic	metabolic	JJ
cord-285778-80baxwgc	40	21	machinery	machinery	NN
cord-285778-80baxwgc	40	22	,	,	,
cord-285778-80baxwgc	40	23	and	and	CC
cord-285778-80baxwgc	40	24	cause	cause	VB
cord-285778-80baxwgc	40	25	it	-PRON-	PRP
cord-285778-80baxwgc	40	26	to	to	TO
cord-285778-80baxwgc	40	27	churn	churn	VB
cord-285778-80baxwgc	40	28	out	out	RP
cord-285778-80baxwgc	40	29	new	new	JJ
cord-285778-80baxwgc	40	30	virus	virus	NN
cord-285778-80baxwgc	40	31	particles	particle	NNS
cord-285778-80baxwgc	40	32	,	,	,
cord-285778-80baxwgc	40	33	bacteria	bacteria	NNS
cord-285778-80baxwgc	40	34	,	,	,
cord-285778-80baxwgc	40	35	or	or	CC
cord-285778-80baxwgc	40	36	parasites	parasite	NNS
cord-285778-80baxwgc	40	37	.	.	.
cord-285778-80baxwgc	41	1	These	these	DT
cord-285778-80baxwgc	41	2	pathogens	pathogen	NNS
cord-285778-80baxwgc	41	3	may	may	MD
cord-285778-80baxwgc	41	4	then	then	RB
cord-285778-80baxwgc	41	5	also	also	RB
cord-285778-80baxwgc	41	6	travel	travel	VB
cord-285778-80baxwgc	41	7	systemically	systemically	RB
cord-285778-80baxwgc	41	8	by	by	IN
cord-285778-80baxwgc	41	9	entering	enter	VBG
cord-285778-80baxwgc	41	10	the	the	DT
cord-285778-80baxwgc	41	11	blood	blood	NN
cord-285778-80baxwgc	41	12	.	.	.
cord-285778-80baxwgc	42	1	For	for	IN
cord-285778-80baxwgc	42	2	both	both	DT
cord-285778-80baxwgc	42	3	intracellular	intracellular	JJ
cord-285778-80baxwgc	42	4	and	and	CC
cord-285778-80baxwgc	42	5	extracellular	extracellular	JJ
cord-285778-80baxwgc	42	6	pathogens	pathogen	NNS
cord-285778-80baxwgc	42	7	,	,	,
cord-285778-80baxwgc	42	8	if	if	IN
cord-285778-80baxwgc	42	9	the	the	DT
cord-285778-80baxwgc	42	10	infectious	infectious	JJ
cord-285778-80baxwgc	42	11	agent	agent	NN
cord-285778-80baxwgc	42	12	overwhelms	overwhelm	VBZ
cord-285778-80baxwgc	42	13	normal	normal	JJ
cord-285778-80baxwgc	42	14	body	body	NN
cord-285778-80baxwgc	42	15	systems	system	NNS
cord-285778-80baxwgc	42	16	or	or	CC
cord-285778-80baxwgc	42	17	interferes	interfere	VBZ
cord-285778-80baxwgc	42	18	with	with	IN
cord-285778-80baxwgc	42	19	cellular	cellular	JJ
cord-285778-80baxwgc	42	20	functions	function	NNS
cord-285778-80baxwgc	42	21	,	,	,
cord-285778-80baxwgc	42	22	the	the	DT
cord-285778-80baxwgc	42	23	body	body	NN
cord-285778-80baxwgc	42	24	becomes	become	VBZ
cord-285778-80baxwgc	42	25	"	"	``
cord-285778-80baxwgc	42	26	sick	sick	JJ
cord-285778-80baxwgc	42	27	.	.	.
cord-285778-80baxwgc	42	28	"	"	''
cord-285778-80baxwgc	43	1	This	this	DT
cord-285778-80baxwgc	43	2	sickness	sickness	NN
cord-285778-80baxwgc	43	3	is	be	VBZ
cord-285778-80baxwgc	43	4	manifested	manifest	VBN
cord-285778-80baxwgc	43	5	as	as	IN
cord-285778-80baxwgc	43	6	a	a	DT
cord-285778-80baxwgc	43	7	set	set	NN
cord-285778-80baxwgc	43	8	of	of	IN
cord-285778-80baxwgc	43	9	characteristic	characteristic	JJ
cord-285778-80baxwgc	43	10	clinical	clinical	JJ
cord-285778-80baxwgc	43	11	symptoms	symptom	NNS
cord-285778-80baxwgc	43	12	that	that	WDT
cord-285778-80baxwgc	43	13	we	-PRON-	PRP
cord-285778-80baxwgc	43	14	call	call	VBP
cord-285778-80baxwgc	43	15	an	an	DT
cord-285778-80baxwgc	43	16	"	"	``
cord-285778-80baxwgc	43	17	illness	illness	NN
cord-285778-80baxwgc	43	18	"	"	''
cord-285778-80baxwgc	43	19	or	or	CC
cord-285778-80baxwgc	43	20	"	"	``
cord-285778-80baxwgc	43	21	disease	disease	NN
cord-285778-80baxwgc	43	22	.	.	.
cord-285778-80baxwgc	43	23	"	"	''
cord-285778-80baxwgc	44	1	Pathogens	pathogen	NNS
cord-285778-80baxwgc	44	2	that	that	WDT
cord-285778-80baxwgc	44	3	are	be	VBP
cord-285778-80baxwgc	44	4	not	not	RB
cord-285778-80baxwgc	44	5	blocked	block	VBN
cord-285778-80baxwgc	44	6	by	by	IN
cord-285778-80baxwgc	44	7	epithelial	epithelial	JJ
cord-285778-80baxwgc	44	8	barriers	barrier	NNS
cord-285778-80baxwgc	44	9	can	can	MD
cord-285778-80baxwgc	44	10	gain	gain	VB
cord-285778-80baxwgc	44	11	access	access	NN
cord-285778-80baxwgc	44	12	to	to	IN
cord-285778-80baxwgc	44	13	underlying	underlying	JJ
cord-285778-80baxwgc	44	14	cell	cell	NN
cord-285778-80baxwgc	44	15	layers	layer	NNS
cord-285778-80baxwgc	44	16	.	.	.
cord-285778-80baxwgc	45	1	Extracellular	Extracellular	NNP
cord-285778-80baxwgc	45	2	pathogens	pathogen	NNS
cord-285778-80baxwgc	45	3	replicate	replicate	VBP
cord-285778-80baxwgc	45	4	outside	outside	JJ
cord-285778-80baxwgc	45	5	host	host	NN
cord-285778-80baxwgc	45	6	cells	cell	NNS
cord-285778-80baxwgc	45	7	,	,	,
cord-285778-80baxwgc	45	8	whereas	whereas	IN
cord-285778-80baxwgc	45	9	intracellular	intracellular	JJ
cord-285778-80baxwgc	45	10	pathogens	pathogen	NNS
cord-285778-80baxwgc	45	11	must	must	MD
cord-285778-80baxwgc	45	12	enter	enter	VB
cord-285778-80baxwgc	45	13	host	host	NN
cord-285778-80baxwgc	45	14	cells	cell	NNS
cord-285778-80baxwgc	45	15	to	to	TO
cord-285778-80baxwgc	45	16	replicate	replicate	VB
cord-285778-80baxwgc	45	17	.	.	.
cord-285778-80baxwgc	46	1	In	in	IN
cord-285778-80baxwgc	46	2	both	both	DT
cord-285778-80baxwgc	46	3	cases	case	NNS
cord-285778-80baxwgc	46	4	,	,	,
cord-285778-80baxwgc	46	5	if	if	IN
cord-285778-80baxwgc	46	6	infection	infection	NN
cord-285778-80baxwgc	46	7	is	be	VBZ
cord-285778-80baxwgc	46	8	not	not	RB
cord-285778-80baxwgc	46	9	controlled	control	VBN
cord-285778-80baxwgc	46	10	,	,	,
cord-285778-80baxwgc	46	11	the	the	DT
cord-285778-80baxwgc	46	12	pathogen	pathogen	NN
cord-285778-80baxwgc	46	13	may	may	MD
cord-285778-80baxwgc	46	14	spread	spread	VB
cord-285778-80baxwgc	46	15	locally	locally	RB
cord-285778-80baxwgc	46	16	in	in	IN
cord-285778-80baxwgc	46	17	the	the	DT
cord-285778-80baxwgc	46	18	tissues	tissue	NNS
cord-285778-80baxwgc	46	19	or	or	CC
cord-285778-80baxwgc	46	20	enter	enter	VB
cord-285778-80baxwgc	46	21	the	the	DT
cord-285778-80baxwgc	46	22	bloodstream	bloodstream	NN
cord-285778-80baxwgc	46	23	and	and	CC
cord-285778-80baxwgc	46	24	spread	spread	VBD
cord-285778-80baxwgc	46	25	systemically	systemically	RB
cord-285778-80baxwgc	46	26	.	.	.
cord-285778-80baxwgc	46	27	 	 	_SP
cord-285778-80baxwgc	47	1	Our	-PRON-	PRP$
cord-285778-80baxwgc	47	2	bodies	body	NNS
cord-285778-80baxwgc	47	3	are	be	VBP
cord-285778-80baxwgc	47	4	under	under	IN
cord-285778-80baxwgc	47	5	constant	constant	JJ
cord-285778-80baxwgc	47	6	assault	assault	NN
cord-285778-80baxwgc	47	7	by	by	IN
cord-285778-80baxwgc	47	8	harmful	harmful	JJ
cord-285778-80baxwgc	47	9	microbes	microbe	NNS
cord-285778-80baxwgc	47	10	,	,	,
cord-285778-80baxwgc	47	11	yet	yet	CC
cord-285778-80baxwgc	47	12	,	,	,
cord-285778-80baxwgc	47	13	most	most	JJS
cord-285778-80baxwgc	47	14	of	of	IN
cord-285778-80baxwgc	47	15	the	the	DT
cord-285778-80baxwgc	47	16	time	time	NN
cord-285778-80baxwgc	47	17	,	,	,
cord-285778-80baxwgc	47	18	assaults	assault	NNS
cord-285778-80baxwgc	47	19	by	by	IN
cord-285778-80baxwgc	47	20	these	these	DT
cord-285778-80baxwgc	47	21	organisms	organism	NNS
cord-285778-80baxwgc	47	22	are	be	VBP
cord-285778-80baxwgc	47	23	successfully	successfully	RB
cord-285778-80baxwgc	47	24	repelled	repel	VBN
cord-285778-80baxwgc	47	25	and	and	CC
cord-285778-80baxwgc	47	26	disease	disease	NN
cord-285778-80baxwgc	47	27	is	be	VBZ
cord-285778-80baxwgc	47	28	prevented	prevent	VBN
cord-285778-80baxwgc	47	29	.	.	.
cord-285778-80baxwgc	48	1	This	this	DT
cord-285778-80baxwgc	48	2	resistance	resistance	NN
cord-285778-80baxwgc	48	3	is	be	VBZ
cord-285778-80baxwgc	48	4	due	due	JJ
cord-285778-80baxwgc	48	5	to	to	IN
cord-285778-80baxwgc	48	6	both	both	CC
cord-285778-80baxwgc	48	7	basic	basic	JJ
cord-285778-80baxwgc	48	8	and	and	CC
cord-285778-80baxwgc	48	9	sophisticated	sophisticated	JJ
cord-285778-80baxwgc	48	10	immune	immune	JJ
cord-285778-80baxwgc	48	11	responses	response	NNS
cord-285778-80baxwgc	48	12	that	that	WDT
cord-285778-80baxwgc	48	13	combat	combat	NN
cord-285778-80baxwgc	48	14	pathogens	pathogen	NNS
cord-285778-80baxwgc	48	15	.	.	.
cord-285778-80baxwgc	49	1	Simply	simply	RB
cord-285778-80baxwgc	49	2	put	put	VBN
cord-285778-80baxwgc	49	3	,	,	,
cord-285778-80baxwgc	49	4	the	the	DT
cord-285778-80baxwgc	49	5	job	job	NN
cord-285778-80baxwgc	49	6	of	of	IN
cord-285778-80baxwgc	49	7	the	the	DT
cord-285778-80baxwgc	49	8	immune	immune	JJ
cord-285778-80baxwgc	49	9	response	response	NN
cord-285778-80baxwgc	49	10	is	be	VBZ
cord-285778-80baxwgc	49	11	to	to	TO
cord-285778-80baxwgc	49	12	"	"	``
cord-285778-80baxwgc	49	13	clean	clean	VB
cord-285778-80baxwgc	49	14	up	up	RP
cord-285778-80baxwgc	49	15	"	"	''
cord-285778-80baxwgc	49	16	infections	infection	NNS
cord-285778-80baxwgc	49	17	in	in	IN
cord-285778-80baxwgc	49	18	the	the	DT
cord-285778-80baxwgc	49	19	interstitial	interstitial	JJ
cord-285778-80baxwgc	49	20	fluid	fluid	NN
cord-285778-80baxwgc	49	21	,	,	,
cord-285778-80baxwgc	49	22	tissues	tissue	NNS
cord-285778-80baxwgc	49	23	and	and	CC
cord-285778-80baxwgc	49	24	blood	blood	NN
cord-285778-80baxwgc	49	25	,	,	,
cord-285778-80baxwgc	49	26	and	and	CC
cord-285778-80baxwgc	49	27	to	to	TO
cord-285778-80baxwgc	49	28	destroy	destroy	VB
cord-285778-80baxwgc	49	29	infected	infected	JJ
cord-285778-80baxwgc	49	30	host	host	NN
cord-285778-80baxwgc	49	31	cells	cell	NNS
cord-285778-80baxwgc	49	32	so	so	IN
cord-285778-80baxwgc	49	33	that	that	IN
cord-285778-80baxwgc	49	34	neighboring	neighboring	NN
cord-285778-80baxwgc	49	35	host	host	NN
cord-285778-80baxwgc	49	36	cells	cell	NNS
cord-285778-80baxwgc	49	37	do	do	VBP
cord-285778-80baxwgc	49	38	not	not	RB
cord-285778-80baxwgc	49	39	share	share	VB
cord-285778-80baxwgc	49	40	their	-PRON-	PRP$
cord-285778-80baxwgc	49	41	fate	fate	NN
cord-285778-80baxwgc	49	42	.	.	.
cord-285778-80baxwgc	50	1	Because	because	IN
cord-285778-80baxwgc	50	2	pathogens	pathogen	NNS
cord-285778-80baxwgc	50	3	are	be	VBP
cord-285778-80baxwgc	50	4	constantly	constantly	RB
cord-285778-80baxwgc	50	5	evolving	evolve	VBG
cord-285778-80baxwgc	50	6	mechanisms	mechanism	NNS
cord-285778-80baxwgc	50	7	to	to	TO
cord-285778-80baxwgc	50	8	evade	evade	VB
cord-285778-80baxwgc	50	9	or	or	CC
cord-285778-80baxwgc	50	10	block	block	VB
cord-285778-80baxwgc	50	11	immune	immune	JJ
cord-285778-80baxwgc	50	12	defenses	defense	NNS
cord-285778-80baxwgc	50	13	,	,	,
cord-285778-80baxwgc	50	14	the	the	DT
cord-285778-80baxwgc	50	15	immune	immune	JJ
cord-285778-80baxwgc	50	16	system	system	NN
cord-285778-80baxwgc	50	17	must	must	MD
cord-285778-80baxwgc	50	18	constantly	constantly	RB
cord-285778-80baxwgc	50	19	adapt	adapt	VB
cord-285778-80baxwgc	50	20	to	to	TO
cord-285778-80baxwgc	50	21	maintain	maintain	VB
cord-285778-80baxwgc	50	22	its	-PRON-	PRP$
cord-285778-80baxwgc	50	23	effectiveness	effectiveness	NN
cord-285778-80baxwgc	50	24	.	.	.
cord-285778-80baxwgc	51	1	It	-PRON-	PRP
cord-285778-80baxwgc	51	2	is	be	VBZ
cord-285778-80baxwgc	51	3	a	a	DT
cord-285778-80baxwgc	51	4	continual	continual	JJ
cord-285778-80baxwgc	51	5	horse	horse	NN
cord-285778-80baxwgc	51	6	race	race	NN
cord-285778-80baxwgc	51	7	as	as	IN
cord-285778-80baxwgc	51	8	to	to	IN
cord-285778-80baxwgc	51	9	which	which	WDT
cord-285778-80baxwgc	51	10	will	will	MD
cord-285778-80baxwgc	51	11	be	be	VB
cord-285778-80baxwgc	51	12	the	the	DT
cord-285778-80baxwgc	51	13	more	more	RBR
cord-285778-80baxwgc	51	14	successful	successful	JJ
cord-285778-80baxwgc	51	15	mechanism	mechanism	NN
cord-285778-80baxwgc	51	16	:	:	:
cord-285778-80baxwgc	51	17	the	the	DT
cord-285778-80baxwgc	51	18	body	body	NN
cord-285778-80baxwgc	51	19	's	's	POS
cord-285778-80baxwgc	51	20	immune	immune	JJ
cord-285778-80baxwgc	51	21	surveillance	surveillance	NN
cord-285778-80baxwgc	51	22	or	or	CC
cord-285778-80baxwgc	51	23	the	the	DT
cord-285778-80baxwgc	51	24	pathogen	pathogen	NN
cord-285778-80baxwgc	51	25	's	's	POS
cord-285778-80baxwgc	51	26	invasion	invasion	NN
cord-285778-80baxwgc	51	27	and	and	CC
cord-285778-80baxwgc	51	28	infection	infection	NN
cord-285778-80baxwgc	51	29	strategy	strategy	NN
cord-285778-80baxwgc	51	30	.	.	.
cord-285778-80baxwgc	52	1	We	-PRON-	PRP
cord-285778-80baxwgc	52	2	note	note	VBP
cord-285778-80baxwgc	52	3	here	here	RB
cord-285778-80baxwgc	52	4	that	that	IN
cord-285778-80baxwgc	52	5	the	the	DT
cord-285778-80baxwgc	52	6	immune	immune	JJ
cord-285778-80baxwgc	52	7	response	response	NN
cord-285778-80baxwgc	52	8	itself	-PRON-	PRP
cord-285778-80baxwgc	52	9	may	may	MD
cord-285778-80baxwgc	52	10	cause	cause	VB
cord-285778-80baxwgc	52	11	limited	limited	JJ
cord-285778-80baxwgc	52	12	collateral	collateral	JJ
cord-285778-80baxwgc	52	13	damage	damage	NN
cord-285778-80baxwgc	52	14	to	to	IN
cord-285778-80baxwgc	52	15	tissues	tissue	NNS
cord-285778-80baxwgc	52	16	as	as	IN
cord-285778-80baxwgc	52	17	part	part	NN
cord-285778-80baxwgc	52	18	of	of	IN
cord-285778-80baxwgc	52	19	its	-PRON-	PRP$
cord-285778-80baxwgc	52	20	larger	large	JJR
cord-285778-80baxwgc	52	21	battle	battle	NN
cord-285778-80baxwgc	52	22	against	against	IN
cord-285778-80baxwgc	52	23	pathogens	pathogen	NNS
cord-285778-80baxwgc	52	24	,	,	,
cord-285778-80baxwgc	52	25	but	but	CC
cord-285778-80baxwgc	52	26	such	such	JJ
cord-285778-80baxwgc	52	27	immunopathic	immunopathic	JJ
cord-285778-80baxwgc	52	28	effects	effect	NNS
cord-285778-80baxwgc	52	29	are	be	VBP
cord-285778-80baxwgc	52	30	usually	usually	RB
cord-285778-80baxwgc	52	31	short	short	RB
cord-285778-80baxwgc	52	32	-	-	HYPH
cord-285778-80baxwgc	52	33	lived	live	VBN
cord-285778-80baxwgc	52	34	in	in	IN
cord-285778-80baxwgc	52	35	an	an	DT
cord-285778-80baxwgc	52	36	otherwise	otherwise	RB
cord-285778-80baxwgc	52	37	healthy	healthy	JJ
cord-285778-80baxwgc	52	38	individual	individual	NN
cord-285778-80baxwgc	52	39	.	.	.
cord-285778-80baxwgc	53	1	At	at	IN
cord-285778-80baxwgc	53	2	the	the	DT
cord-285778-80baxwgc	53	3	turn	turn	NN
cord-285778-80baxwgc	53	4	of	of	IN
cord-285778-80baxwgc	53	5	the	the	DT
cord-285778-80baxwgc	53	6	twentieth	twentieth	JJ
cord-285778-80baxwgc	53	7	century	century	NN
cord-285778-80baxwgc	53	8	,	,	,
cord-285778-80baxwgc	53	9	there	there	EX
cord-285778-80baxwgc	53	10	were	be	VBD
cord-285778-80baxwgc	53	11	two	two	CD
cord-285778-80baxwgc	53	12	schools	school	NNS
cord-285778-80baxwgc	53	13	of	of	IN
cord-285778-80baxwgc	53	14	thought	thought	NN
cord-285778-80baxwgc	53	15	on	on	IN
cord-285778-80baxwgc	53	16	what	what	WP
cord-285778-80baxwgc	53	17	mechanisms	mechanism	NNS
cord-285778-80baxwgc	53	18	underlay	underlay	VBP
cord-285778-80baxwgc	53	19	immune	immune	JJ
cord-285778-80baxwgc	53	20	responses	response	NNS
cord-285778-80baxwgc	53	21	.	.	.
cord-285778-80baxwgc	54	1	One	one	CD
cord-285778-80baxwgc	54	2	group	group	NN
cord-285778-80baxwgc	54	3	of	of	IN
cord-285778-80baxwgc	54	4	scientists	scientist	NNS
cord-285778-80baxwgc	54	5	believed	believe	VBD
cord-285778-80baxwgc	54	6	that	that	IN
cord-285778-80baxwgc	54	7	immunity	immunity	NN
cord-285778-80baxwgc	54	8	depended	depend	VBD
cord-285778-80baxwgc	54	9	primarily	primarily	RB
cord-285778-80baxwgc	54	10	on	on	IN
cord-285778-80baxwgc	54	11	the	the	DT
cord-285778-80baxwgc	54	12	actions	action	NNS
cord-285778-80baxwgc	54	13	of	of	IN
cord-285778-80baxwgc	54	14	cells	cell	NNS
cord-285778-80baxwgc	54	15	that	that	WDT
cord-285778-80baxwgc	54	16	destroyed	destroy	VBD
cord-285778-80baxwgc	54	17	or	or	CC
cord-285778-80baxwgc	54	18	removed	remove	VBN
cord-285778-80baxwgc	54	19	unwanted	unwanted	JJ
cord-285778-80baxwgc	54	20	material	material	NN
cord-285778-80baxwgc	54	21	from	from	IN
cord-285778-80baxwgc	54	22	the	the	DT
cord-285778-80baxwgc	54	23	body	body	NN
cord-285778-80baxwgc	54	24	.	.	.
cord-285778-80baxwgc	55	1	This	this	DT
cord-285778-80baxwgc	55	2	clearance	clearance	NN
cord-285778-80baxwgc	55	3	process	process	NN
cord-285778-80baxwgc	55	4	was	be	VBD
cord-285778-80baxwgc	55	5	referred	refer	VBN
cord-285778-80baxwgc	55	6	to	to	IN
cord-285778-80baxwgc	55	7	as	as	IN
cord-285778-80baxwgc	55	8	cell	cell	NN
cord-285778-80baxwgc	55	9	-	-	HYPH
cord-285778-80baxwgc	55	10	mediated	mediate	VBN
cord-285778-80baxwgc	55	11	immunity	immunity	NN
cord-285778-80baxwgc	55	12	.	.	.
cord-285778-80baxwgc	56	1	However	however	RB
cord-285778-80baxwgc	56	2	,	,	,
cord-285778-80baxwgc	56	3	another	another	DT
cord-285778-80baxwgc	56	4	group	group	NN
cord-285778-80baxwgc	56	5	of	of	IN
cord-285778-80baxwgc	56	6	researchers	researcher	NNS
cord-285778-80baxwgc	56	7	was	be	VBD
cord-285778-80baxwgc	56	8	convinced	convince	VBN
cord-285778-80baxwgc	56	9	that	that	IN
cord-285778-80baxwgc	56	10	soluble	soluble	JJ
cord-285778-80baxwgc	56	11	molecules	molecule	NNS
cord-285778-80baxwgc	56	12	in	in	IN
cord-285778-80baxwgc	56	13	the	the	DT
cord-285778-80baxwgc	56	14	serum	serum	NN
cord-285778-80baxwgc	56	15	of	of	IN
cord-285778-80baxwgc	56	16	the	the	DT
cord-285778-80baxwgc	56	17	blood	blood	NN
cord-285778-80baxwgc	56	18	could	could	MD
cord-285778-80baxwgc	56	19	directly	directly	RB
cord-285778-80baxwgc	56	20	eliminate	eliminate	VB
cord-285778-80baxwgc	56	21	foreign	foreign	JJ
cord-285778-80baxwgc	56	22	entities	entity	NNS
cord-285778-80baxwgc	56	23	without	without	IN
cord-285778-80baxwgc	56	24	the	the	DT
cord-285778-80baxwgc	56	25	need	need	NN
cord-285778-80baxwgc	56	26	for	for	IN
cord-285778-80baxwgc	56	27	cellular	cellular	JJ
cord-285778-80baxwgc	56	28	involvement	involvement	NN
cord-285778-80baxwgc	56	29	.	.	.
cord-285778-80baxwgc	57	1	In	in	IN
cord-285778-80baxwgc	57	2	this	this	DT
cord-285778-80baxwgc	57	3	case	case	NN
cord-285778-80baxwgc	57	4	,	,	,
cord-285778-80baxwgc	57	5	the	the	DT
cord-285778-80baxwgc	57	6	clearance	clearance	NN
cord-285778-80baxwgc	57	7	process	process	NN
cord-285778-80baxwgc	57	8	was	be	VBD
cord-285778-80baxwgc	57	9	referred	refer	VBN
cord-285778-80baxwgc	57	10	to	to	IN
cord-285778-80baxwgc	57	11	as	as	RB
cord-285778-80baxwgc	57	12	humoral	humoral	JJ
cord-285778-80baxwgc	57	13	immunity	immunity	NN
cord-285778-80baxwgc	57	14	,	,	,
cord-285778-80baxwgc	57	15	a	a	DT
cord-285778-80baxwgc	57	16	term	term	NN
cord-285778-80baxwgc	57	17	derived	derive	VBN
cord-285778-80baxwgc	57	18	from	from	IN
cord-285778-80baxwgc	57	19	the	the	DT
cord-285778-80baxwgc	57	20	historical	historical	JJ
cord-285778-80baxwgc	57	21	description	description	NN
cord-285778-80baxwgc	57	22	of	of	IN
cord-285778-80baxwgc	57	23	body	body	NN
cord-285778-80baxwgc	57	24	fluids	fluid	NNS
cord-285778-80baxwgc	57	25	as	as	IN
cord-285778-80baxwgc	57	26	"	"	``
cord-285778-80baxwgc	57	27	humors	humor	NNS
cord-285778-80baxwgc	57	28	.	.	.
cord-285778-80baxwgc	57	29	"	"	''
cord-285778-80baxwgc	58	1	Today	today	NN
cord-285778-80baxwgc	58	2	,	,	,
cord-285778-80baxwgc	58	3	we	-PRON-	PRP
cord-285778-80baxwgc	58	4	know	know	VBP
cord-285778-80baxwgc	58	5	that	that	IN
cord-285778-80baxwgc	58	6	both	both	DT
cord-285778-80baxwgc	58	7	cell	cell	NN
cord-285778-80baxwgc	58	8	-	-	HYPH
cord-285778-80baxwgc	58	9	mediated	mediate	VBN
cord-285778-80baxwgc	58	10	and	and	CC
cord-285778-80baxwgc	58	11	humoral	humoral	JJ
cord-285778-80baxwgc	58	12	responses	response	NNS
cord-285778-80baxwgc	58	13	occur	occur	VBP
cord-285778-80baxwgc	58	14	simultaneously	simultaneously	RB
cord-285778-80baxwgc	58	15	during	during	IN
cord-285778-80baxwgc	58	16	an	an	DT
cord-285778-80baxwgc	58	17	immune	immune	JJ
cord-285778-80baxwgc	58	18	response	response	NN
cord-285778-80baxwgc	58	19	and	and	CC
cord-285778-80baxwgc	58	20	that	that	IN
cord-285778-80baxwgc	58	21	both	both	DT
cord-285778-80baxwgc	58	22	are	be	VBP
cord-285778-80baxwgc	58	23	often	often	RB
cord-285778-80baxwgc	58	24	required	require	VBN
cord-285778-80baxwgc	58	25	for	for	IN
cord-285778-80baxwgc	58	26	complete	complete	JJ
cord-285778-80baxwgc	58	27	clearance	clearance	NN
cord-285778-80baxwgc	58	28	of	of	IN
cord-285778-80baxwgc	58	29	a	a	DT
cord-285778-80baxwgc	58	30	threat	threat	NN
cord-285778-80baxwgc	58	31	.	.	.
cord-285778-80baxwgc	59	1	The	the	DT
cord-285778-80baxwgc	59	2	cells	cell	NNS
cord-285778-80baxwgc	59	3	responsible	responsible	JJ
cord-285778-80baxwgc	59	4	for	for	IN
cord-285778-80baxwgc	59	5	cell	cell	NN
cord-285778-80baxwgc	59	6	-	-	HYPH
cord-285778-80baxwgc	59	7	mediated	mediate	VBN
cord-285778-80baxwgc	59	8	immunity	immunity	NN
cord-285778-80baxwgc	59	9	are	be	VBP
cord-285778-80baxwgc	59	10	collectively	collectively	RB
cord-285778-80baxwgc	59	11	called	call	VBN
cord-285778-80baxwgc	59	12	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	59	13	(	(	-LRB-
cord-285778-80baxwgc	59	14	"	"	``
cord-285778-80baxwgc	59	15	leuko	leuko	FW
cord-285778-80baxwgc	59	16	,	,	,
cord-285778-80baxwgc	59	17	"	"	''
cord-285778-80baxwgc	59	18	white	white	JJ
cord-285778-80baxwgc	59	19	;	;	:
cord-285778-80baxwgc	59	20	"	"	''
cord-285778-80baxwgc	59	21	cyte	cyte	NN
cord-285778-80baxwgc	59	22	,	,	,
cord-285778-80baxwgc	59	23	"	"	''
cord-285778-80baxwgc	59	24	small	small	JJ
cord-285778-80baxwgc	59	25	body	body	NN
cord-285778-80baxwgc	59	26	,	,	,
cord-285778-80baxwgc	59	27	i.e.	i.e.	FW
cord-285778-80baxwgc	59	28	,	,	,
cord-285778-80baxwgc	59	29	a	a	DT
cord-285778-80baxwgc	59	30	cell	cell	NN
cord-285778-80baxwgc	59	31	)	)	-RRB-
cord-285778-80baxwgc	59	32	or	or	CC
cord-285778-80baxwgc	59	33	white	white	JJ
cord-285778-80baxwgc	59	34	blood	blood	NN
cord-285778-80baxwgc	59	35	cells	cell	NNS
cord-285778-80baxwgc	59	36	.	.	.
cord-285778-80baxwgc	60	1	However	however	RB
cord-285778-80baxwgc	60	2	,	,	,
cord-285778-80baxwgc	60	3	"	"	``
cord-285778-80baxwgc	60	4	blood	blood	NN
cord-285778-80baxwgc	60	5	cell	cell	NN
cord-285778-80baxwgc	60	6	"	"	''
cord-285778-80baxwgc	60	7	is	be	VBZ
cord-285778-80baxwgc	60	8	a	a	DT
cord-285778-80baxwgc	60	9	bit	bit	NN
cord-285778-80baxwgc	60	10	of	of	IN
cord-285778-80baxwgc	60	11	a	a	DT
cord-285778-80baxwgc	60	12	misnomer	misnomer	NN
cord-285778-80baxwgc	60	13	,	,	,
cord-285778-80baxwgc	60	14	because	because	IN
cord-285778-80baxwgc	60	15	a	a	DT
cord-285778-80baxwgc	60	16	majority	majority	NN
cord-285778-80baxwgc	60	17	of	of	IN
cord-285778-80baxwgc	60	18	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	60	19	reside	reside	VBP
cord-285778-80baxwgc	60	20	in	in	IN
cord-285778-80baxwgc	60	21	tissues	tissue	NNS
cord-285778-80baxwgc	60	22	and	and	CC
cord-285778-80baxwgc	60	23	specialized	specialized	JJ
cord-285778-80baxwgc	60	24	organs	organ	NNS
cord-285778-80baxwgc	60	25	,	,	,
cord-285778-80baxwgc	60	26	and	and	CC
cord-285778-80baxwgc	60	27	move	move	VB
cord-285778-80baxwgc	60	28	around	around	IN
cord-285778-80baxwgc	60	29	the	the	DT
cord-285778-80baxwgc	60	30	body	body	NN
cord-285778-80baxwgc	60	31	through	through	IN
cord-285778-80baxwgc	60	32	both	both	CC
cord-285778-80baxwgc	60	33	the	the	DT
cord-285778-80baxwgc	60	34	blood	blood	NN
cord-285778-80baxwgc	60	35	circulation	circulation	NN
cord-285778-80baxwgc	60	36	and	and	CC
cord-285778-80baxwgc	60	37	a	a	DT
cord-285778-80baxwgc	60	38	system	system	NN
cord-285778-80baxwgc	60	39	of	of	IN
cord-285778-80baxwgc	60	40	interconnected	interconnected	JJ
cord-285778-80baxwgc	60	41	vessels	vessel	NNS
cord-285778-80baxwgc	60	42	called	call	VBN
cord-285778-80baxwgc	60	43	the	the	DT
cord-285778-80baxwgc	60	44	lymphatic	lymphatic	JJ
cord-285778-80baxwgc	60	45	system	system	NN
cord-285778-80baxwgc	60	46	.	.	.
cord-285778-80baxwgc	61	1	The	the	DT
cord-285778-80baxwgc	61	2	soluble	soluble	JJ
cord-285778-80baxwgc	61	3	molecules	molecule	NNS
cord-285778-80baxwgc	61	4	responsible	responsible	JJ
cord-285778-80baxwgc	61	5	for	for	IN
cord-285778-80baxwgc	61	6	humoral	humoral	JJ
cord-285778-80baxwgc	61	7	immunity	immunity	NN
cord-285778-80baxwgc	61	8	are	be	VBP
cord-285778-80baxwgc	61	9	proteins	protein	NNS
cord-285778-80baxwgc	61	10	called	call	VBN
cord-285778-80baxwgc	61	11	antibodies	antibody	NNS
cord-285778-80baxwgc	61	12	,	,	,
cord-285778-80baxwgc	61	13	and	and	CC
cord-285778-80baxwgc	61	14	antibodies	antibody	NNS
cord-285778-80baxwgc	61	15	are	be	VBP
cord-285778-80baxwgc	61	16	secreted	secrete	VBN
cord-285778-80baxwgc	61	17	by	by	IN
cord-285778-80baxwgc	61	18	a	a	DT
cord-285778-80baxwgc	61	19	particular	particular	JJ
cord-285778-80baxwgc	61	20	type	type	NN
cord-285778-80baxwgc	61	21	of	of	IN
cord-285778-80baxwgc	61	22	leukocyte	leukocyte	NN
cord-285778-80baxwgc	61	23	.	.	.
cord-285778-80baxwgc	62	1	The	the	DT
cord-285778-80baxwgc	62	2	production	production	NN
cord-285778-80baxwgc	62	3	of	of	IN
cord-285778-80baxwgc	62	4	these	these	DT
cord-285778-80baxwgc	62	5	antibodies	antibody	NNS
cord-285778-80baxwgc	62	6	and	and	CC
cord-285778-80baxwgc	62	7	the	the	DT
cord-285778-80baxwgc	62	8	mounting	mounting	NN
cord-285778-80baxwgc	62	9	of	of	IN
cord-285778-80baxwgc	62	10	cell	cell	NN
cord-285778-80baxwgc	62	11	-	-	HYPH
cord-285778-80baxwgc	62	12	mediated	mediate	VBN
cord-285778-80baxwgc	62	13	immune	immune	JJ
cord-285778-80baxwgc	62	14	responses	response	NNS
cord-285778-80baxwgc	62	15	depend	depend	VBP
cord-285778-80baxwgc	62	16	on	on	IN
cord-285778-80baxwgc	62	17	an	an	DT
cord-285778-80baxwgc	62	18	elaborate	elaborate	JJ
cord-285778-80baxwgc	62	19	signaling	signal	VBG
cord-285778-80baxwgc	62	20	system	system	NN
cord-285778-80baxwgc	62	21	by	by	IN
cord-285778-80baxwgc	62	22	which	which	WDT
cord-285778-80baxwgc	62	23	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	62	24	communicate	communicate	VBP
cord-285778-80baxwgc	62	25	with	with	IN
cord-285778-80baxwgc	62	26	each	each	DT
cord-285778-80baxwgc	62	27	other	other	JJ
cord-285778-80baxwgc	62	28	as	as	RB
cord-285778-80baxwgc	62	29	well	well	RB
cord-285778-80baxwgc	62	30	as	as	IN
cord-285778-80baxwgc	62	31	with	with	IN
cord-285778-80baxwgc	62	32	other	other	JJ
cord-285778-80baxwgc	62	33	cell	cell	NN
cord-285778-80baxwgc	62	34	types	type	NNS
cord-285778-80baxwgc	62	35	in	in	IN
cord-285778-80baxwgc	62	36	the	the	DT
cord-285778-80baxwgc	62	37	body	body	NN
cord-285778-80baxwgc	62	38	.	.	.
cord-285778-80baxwgc	63	1	This	this	DT
cord-285778-80baxwgc	63	2	signaling	signaling	NN
cord-285778-80baxwgc	63	3	is	be	VBZ
cord-285778-80baxwgc	63	4	mediated	mediate	VBN
cord-285778-80baxwgc	63	5	by	by	IN
cord-285778-80baxwgc	63	6	small	small	JJ
cord-285778-80baxwgc	63	7	secreted	secrete	VBN
cord-285778-80baxwgc	63	8	proteins	protein	NNS
cord-285778-80baxwgc	63	9	called	call	VBN
cord-285778-80baxwgc	63	10	cytokines	cytokine	NNS
cord-285778-80baxwgc	63	11	,	,	,
cord-285778-80baxwgc	63	12	which	which	WDT
cord-285778-80baxwgc	63	13	are	be	VBP
cord-285778-80baxwgc	63	14	mainly	mainly	RB
cord-285778-80baxwgc	63	15	produced	produce	VBN
cord-285778-80baxwgc	63	16	by	by	IN
cord-285778-80baxwgc	63	17	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	63	18	.	.	.
cord-285778-80baxwgc	64	1	The	the	DT
cord-285778-80baxwgc	64	2	mammalian	mammalian	JJ
cord-285778-80baxwgc	64	3	immune	immune	JJ
cord-285778-80baxwgc	64	4	system	system	NN
cord-285778-80baxwgc	64	5	can	can	MD
cord-285778-80baxwgc	64	6	mount	mount	VB
cord-285778-80baxwgc	64	7	two	two	CD
cord-285778-80baxwgc	64	8	types	type	NNS
cord-285778-80baxwgc	64	9	of	of	IN
cord-285778-80baxwgc	64	10	responses	response	NNS
cord-285778-80baxwgc	64	11	:	:	:
cord-285778-80baxwgc	64	12	the	the	DT
cord-285778-80baxwgc	64	13	innate	innate	JJ
cord-285778-80baxwgc	64	14	response	response	NN
cord-285778-80baxwgc	64	15	and	and	CC
cord-285778-80baxwgc	64	16	the	the	DT
cord-285778-80baxwgc	64	17	adaptive	adaptive	JJ
cord-285778-80baxwgc	64	18	response	response	NN
cord-285778-80baxwgc	64	19	.	.	.
cord-285778-80baxwgc	65	1	Recently	recently	RB
cord-285778-80baxwgc	65	2	,	,	,
cord-285778-80baxwgc	65	3	it	-PRON-	PRP
cord-285778-80baxwgc	65	4	has	have	VBZ
cord-285778-80baxwgc	65	5	become	become	VBN
cord-285778-80baxwgc	65	6	increasingly	increasingly	RB
cord-285778-80baxwgc	65	7	clear	clear	JJ
cord-285778-80baxwgc	65	8	that	that	IN
cord-285778-80baxwgc	65	9	these	these	DT
cord-285778-80baxwgc	65	10	two	two	CD
cord-285778-80baxwgc	65	11	types	type	NNS
cord-285778-80baxwgc	65	12	of	of	IN
cord-285778-80baxwgc	65	13	responses	response	NNS
cord-285778-80baxwgc	65	14	are	be	VBP
cord-285778-80baxwgc	65	15	less	less	RBR
cord-285778-80baxwgc	65	16	distinct	distinct	JJ
cord-285778-80baxwgc	65	17	and	and	CC
cord-285778-80baxwgc	65	18	more	more	RBR
cord-285778-80baxwgc	65	19	interconnected	interconnected	JJ
cord-285778-80baxwgc	65	20	than	than	IN
cord-285778-80baxwgc	65	21	once	once	RB
cord-285778-80baxwgc	65	22	thought	think	VBN
cord-285778-80baxwgc	65	23	.	.	.
cord-285778-80baxwgc	66	1	Indeed	indeed	RB
cord-285778-80baxwgc	66	2	,	,	,
cord-285778-80baxwgc	66	3	researchers	researcher	NNS
cord-285778-80baxwgc	66	4	now	now	RB
cord-285778-80baxwgc	66	5	believe	believe	VBP
cord-285778-80baxwgc	66	6	that	that	IN
cord-285778-80baxwgc	66	7	vertebrates	vertebrate	NNS
cord-285778-80baxwgc	66	8	are	be	VBP
cord-285778-80baxwgc	66	9	capable	capable	JJ
cord-285778-80baxwgc	66	10	of	of	IN
cord-285778-80baxwgc	66	11	a	a	DT
cord-285778-80baxwgc	66	12	continuum	continuum	NN
cord-285778-80baxwgc	66	13	of	of	IN
cord-285778-80baxwgc	66	14	immune	immune	JJ
cord-285778-80baxwgc	66	15	responses	response	NNS
cord-285778-80baxwgc	66	16	that	that	WDT
cord-285778-80baxwgc	66	17	bring	bring	VBP
cord-285778-80baxwgc	66	18	more	more	JJR
cord-285778-80baxwgc	66	19	and	and	CC
cord-285778-80baxwgc	66	20	more	more	RBR
cord-285778-80baxwgc	66	21	precise	precise	JJ
cord-285778-80baxwgc	66	22	weapons	weapon	NNS
cord-285778-80baxwgc	66	23	to	to	TO
cord-285778-80baxwgc	66	24	bear	bear	VB
cord-285778-80baxwgc	66	25	on	on	IN
cord-285778-80baxwgc	66	26	a	a	DT
cord-285778-80baxwgc	66	27	threat	threat	NN
cord-285778-80baxwgc	66	28	as	as	IN
cord-285778-80baxwgc	66	29	required	require	VBN
cord-285778-80baxwgc	66	30	.	.	.
cord-285778-80baxwgc	67	1	More	more	RBR
cord-285778-80baxwgc	67	2	specifically	specifically	RB
cord-285778-80baxwgc	67	3	,	,	,
cord-285778-80baxwgc	67	4	innate	innate	JJ
cord-285778-80baxwgc	67	5	immunity	immunity	NN
cord-285778-80baxwgc	67	6	is	be	VBZ
cord-285778-80baxwgc	67	7	involved	involve	VBN
cord-285778-80baxwgc	67	8	in	in	IN
cord-285778-80baxwgc	67	9	all	all	DT
cord-285778-80baxwgc	67	10	levels	level	NNS
cord-285778-80baxwgc	67	11	of	of	IN
cord-285778-80baxwgc	67	12	immune	immune	JJ
cord-285778-80baxwgc	67	13	response	response	NN
cord-285778-80baxwgc	67	14	,	,	,
cord-285778-80baxwgc	67	15	whereas	whereas	IN
cord-285778-80baxwgc	67	16	the	the	DT
cord-285778-80baxwgc	67	17	adaptive	adaptive	JJ
cord-285778-80baxwgc	67	18	response	response	NN
cord-285778-80baxwgc	67	19	is	be	VBZ
cord-285778-80baxwgc	67	20	mounted	mount	VBN
cord-285778-80baxwgc	67	21	only	only	RB
cord-285778-80baxwgc	67	22	when	when	WRB
cord-285778-80baxwgc	67	23	innate	innate	JJ
cord-285778-80baxwgc	67	24	mechanisms	mechanism	NNS
cord-285778-80baxwgc	67	25	signal	signal	VBP
cord-285778-80baxwgc	67	26	that	that	IN
cord-285778-80baxwgc	67	27	there	there	EX
cord-285778-80baxwgc	67	28	is	be	VBZ
cord-285778-80baxwgc	67	29	a	a	DT
cord-285778-80baxwgc	67	30	relatively	relatively	RB
cord-285778-80baxwgc	67	31	serious	serious	JJ
cord-285778-80baxwgc	67	32	infection	infection	NN
cord-285778-80baxwgc	67	33	.	.	.
cord-285778-80baxwgc	68	1	In	in	IN
cord-285778-80baxwgc	68	2	all	all	DT
cord-285778-80baxwgc	68	3	cases	case	NNS
cord-285778-80baxwgc	68	4	,	,	,
cord-285778-80baxwgc	68	5	the	the	DT
cord-285778-80baxwgc	68	6	objective	objective	NN
cord-285778-80baxwgc	68	7	is	be	VBZ
cord-285778-80baxwgc	68	8	to	to	TO
cord-285778-80baxwgc	68	9	clear	clear	VB
cord-285778-80baxwgc	68	10	the	the	DT
cord-285778-80baxwgc	68	11	body	body	NN
cord-285778-80baxwgc	68	12	of	of	IN
cord-285778-80baxwgc	68	13	unwanted	unwanted	JJ
cord-285778-80baxwgc	68	14	entities	entity	NNS
cord-285778-80baxwgc	68	15	and	and	CC
cord-285778-80baxwgc	68	16	re	re	VB
cord-285778-80baxwgc	68	17	-	-	VB
cord-285778-80baxwgc	68	18	establish	establish	VB
cord-285778-80baxwgc	68	19	homeostasis	homeostasis	NN
cord-285778-80baxwgc	68	20	in	in	IN
cord-285778-80baxwgc	68	21	the	the	DT
cord-285778-80baxwgc	68	22	most	most	RBS
cord-285778-80baxwgc	68	23	efficient	efficient	JJ
cord-285778-80baxwgc	68	24	way	way	NN
cord-285778-80baxwgc	68	25	possible	possible	JJ
cord-285778-80baxwgc	68	26	.	.	.
cord-285778-80baxwgc	69	1	Innate	innate	JJ
cord-285778-80baxwgc	69	2	immune	immune	JJ
cord-285778-80baxwgc	69	3	responses	response	NNS
cord-285778-80baxwgc	69	4	are	be	VBP
cord-285778-80baxwgc	69	5	triggered	trigger	VBN
cord-285778-80baxwgc	69	6	by	by	IN
cord-285778-80baxwgc	69	7	disruptions	disruption	NNS
cord-285778-80baxwgc	69	8	to	to	IN
cord-285778-80baxwgc	69	9	homeostasis	homeostasis	NN
cord-285778-80baxwgc	69	10	caused	cause	VBN
cord-285778-80baxwgc	69	11	by	by	IN
cord-285778-80baxwgc	69	12	either	either	DT
cord-285778-80baxwgc	69	13	non	non	JJ
cord-285778-80baxwgc	69	14	-	-	JJ
cord-285778-80baxwgc	69	15	infectious	infectious	JJ
cord-285778-80baxwgc	69	16	or	or	CC
cord-285778-80baxwgc	69	17	infectious	infectious	JJ
cord-285778-80baxwgc	69	18	means	mean	NNS
cord-285778-80baxwgc	69	19	.	.	.
cord-285778-80baxwgc	70	1	With	with	IN
cord-285778-80baxwgc	70	2	respect	respect	NN
cord-285778-80baxwgc	70	3	to	to	IN
cord-285778-80baxwgc	70	4	the	the	DT
cord-285778-80baxwgc	70	5	former	former	JJ
cord-285778-80baxwgc	70	6	,	,	,
cord-285778-80baxwgc	70	7	innate	innate	JJ
cord-285778-80baxwgc	70	8	responses	response	NNS
cord-285778-80baxwgc	70	9	help	help	VBP
cord-285778-80baxwgc	70	10	to	to	TO
cord-285778-80baxwgc	70	11	repair	repair	VB
cord-285778-80baxwgc	70	12	tissues	tissue	NNS
cord-285778-80baxwgc	70	13	injured	injure	VBN
cord-285778-80baxwgc	70	14	by	by	IN
cord-285778-80baxwgc	70	15	trauma	trauma	NN
cord-285778-80baxwgc	70	16	(	(	-LRB-
cord-285778-80baxwgc	70	17	such	such	JJ
cord-285778-80baxwgc	70	18	as	as	IN
cord-285778-80baxwgc	70	19	that	that	DT
cord-285778-80baxwgc	70	20	caused	cause	VBN
cord-285778-80baxwgc	70	21	by	by	IN
cord-285778-80baxwgc	70	22	a	a	DT
cord-285778-80baxwgc	70	23	cut	cut	NN
cord-285778-80baxwgc	70	24	,	,	,
cord-285778-80baxwgc	70	25	a	a	DT
cord-285778-80baxwgc	70	26	blow	blow	NN
cord-285778-80baxwgc	70	27	,	,	,
cord-285778-80baxwgc	70	28	or	or	CC
cord-285778-80baxwgc	70	29	surgery	surgery	NN
cord-285778-80baxwgc	70	30	)	)	-RRB-
cord-285778-80baxwgc	70	31	and	and	CC
cord-285778-80baxwgc	70	32	remove	remove	VB
cord-285778-80baxwgc	70	33	dead	dead	JJ
cord-285778-80baxwgc	70	34	cells	cell	NNS
cord-285778-80baxwgc	70	35	and	and	CC
cord-285778-80baxwgc	70	36	cells	cell	NNS
cord-285778-80baxwgc	70	37	too	too	RB
cord-285778-80baxwgc	70	38	damaged	damaged	JJ
cord-285778-80baxwgc	70	39	or	or	CC
cord-285778-80baxwgc	70	40	old	old	JJ
cord-285778-80baxwgc	70	41	(	(	-LRB-
cord-285778-80baxwgc	70	42	senescent	senescent	JJ
cord-285778-80baxwgc	70	43	)	)	-RRB-
cord-285778-80baxwgc	70	44	to	to	TO
cord-285778-80baxwgc	70	45	be	be	VB
cord-285778-80baxwgc	70	46	of	of	IN
cord-285778-80baxwgc	70	47	further	further	JJ
cord-285778-80baxwgc	70	48	use	use	NN
cord-285778-80baxwgc	70	49	to	to	IN
cord-285778-80baxwgc	70	50	the	the	DT
cord-285778-80baxwgc	70	51	body	body	NN
cord-285778-80baxwgc	70	52	.	.	.
cord-285778-80baxwgc	71	1	Products	product	NNS
cord-285778-80baxwgc	71	2	synthesized	synthesize	VBN
cord-285778-80baxwgc	71	3	by	by	IN
cord-285778-80baxwgc	71	4	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	71	5	mediating	mediate	VBG
cord-285778-80baxwgc	71	6	innate	innate	JJ
cord-285778-80baxwgc	71	7	responses	response	NNS
cord-285778-80baxwgc	71	8	(	(	-LRB-
cord-285778-80baxwgc	71	9	innate	innate	JJ
cord-285778-80baxwgc	71	10	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	71	11	)	)	-RRB-
cord-285778-80baxwgc	71	12	also	also	RB
cord-285778-80baxwgc	71	13	help	help	VBP
cord-285778-80baxwgc	71	14	to	to	TO
cord-285778-80baxwgc	71	15	prevent	prevent	VB
cord-285778-80baxwgc	71	16	"	"	``
cord-285778-80baxwgc	71	17	bystander	bystander	NN
cord-285778-80baxwgc	71	18	injury	injury	NN
cord-285778-80baxwgc	71	19	"	"	''
cord-285778-80baxwgc	71	20	of	of	IN
cord-285778-80baxwgc	71	21	healthy	healthy	JJ
cord-285778-80baxwgc	71	22	tissues	tissue	NNS
cord-285778-80baxwgc	71	23	.	.	.
cord-285778-80baxwgc	72	1	With	with	IN
cord-285778-80baxwgc	72	2	respect	respect	NN
cord-285778-80baxwgc	72	3	to	to	IN
cord-285778-80baxwgc	72	4	invading	invade	VBG
cord-285778-80baxwgc	72	5	pathogens	pathogen	NNS
cord-285778-80baxwgc	72	6	,	,	,
cord-285778-80baxwgc	72	7	elements	element	NNS
cord-285778-80baxwgc	72	8	of	of	IN
cord-285778-80baxwgc	72	9	the	the	DT
cord-285778-80baxwgc	72	10	innate	innate	JJ
cord-285778-80baxwgc	72	11	immune	immune	JJ
cord-285778-80baxwgc	72	12	system	system	NN
cord-285778-80baxwgc	72	13	are	be	VBP
cord-285778-80baxwgc	72	14	the	the	DT
cord-285778-80baxwgc	72	15	first	first	JJ
cord-285778-80baxwgc	72	16	to	to	TO
cord-285778-80baxwgc	72	17	confront	confront	VB
cord-285778-80baxwgc	72	18	the	the	DT
cord-285778-80baxwgc	72	19	threat	threat	NN
cord-285778-80baxwgc	72	20	and	and	CC
cord-285778-80baxwgc	72	21	work	work	NN
cord-285778-80baxwgc	72	22	to	to	TO
cord-285778-80baxwgc	72	23	eliminate	eliminate	VB
cord-285778-80baxwgc	72	24	it	-PRON-	PRP
cord-285778-80baxwgc	72	25	from	from	IN
cord-285778-80baxwgc	72	26	the	the	DT
cord-285778-80baxwgc	72	27	body	body	NN
cord-285778-80baxwgc	72	28	.	.	.
cord-285778-80baxwgc	73	1	Such	such	JJ
cord-285778-80baxwgc	73	2	elements	element	NNS
cord-285778-80baxwgc	73	3	include	include	VBP
cord-285778-80baxwgc	73	4	preexisting	preexist	VBG
cord-285778-80baxwgc	73	5	anatomical	anatomical	JJ
cord-285778-80baxwgc	73	6	and	and	CC
cord-285778-80baxwgc	73	7	physiological	physiological	JJ
cord-285778-80baxwgc	73	8	barriers	barrier	NNS
cord-285778-80baxwgc	73	9	that	that	WDT
cord-285778-80baxwgc	73	10	attempt	attempt	VBP
cord-285778-80baxwgc	73	11	to	to	TO
cord-285778-80baxwgc	73	12	block	block	VB
cord-285778-80baxwgc	73	13	pathogen	pathogen	NN
cord-285778-80baxwgc	73	14	entry	entry	NN
cord-285778-80baxwgc	73	15	,	,	,
cord-285778-80baxwgc	73	16	and	and	CC
cord-285778-80baxwgc	73	17	other	other	JJ
cord-285778-80baxwgc	73	18	responses	response	NNS
cord-285778-80baxwgc	73	19	that	that	WDT
cord-285778-80baxwgc	73	20	are	be	VBP
cord-285778-80baxwgc	73	21	induced	induce	VBN
cord-285778-80baxwgc	73	22	after	after	IN
cord-285778-80baxwgc	73	23	the	the	DT
cord-285778-80baxwgc	73	24	pathogen	pathogen	NN
cord-285778-80baxwgc	73	25	has	have	VBZ
cord-285778-80baxwgc	73	26	gained	gain	VBN
cord-285778-80baxwgc	73	27	entry	entry	NN
cord-285778-80baxwgc	73	28	.	.	.
cord-285778-80baxwgc	74	1	Only	only	RB
cord-285778-80baxwgc	74	2	if	if	IN
cord-285778-80baxwgc	74	3	innate	innate	JJ
cord-285778-80baxwgc	74	4	responses	response	NNS
cord-285778-80baxwgc	74	5	are	be	VBP
cord-285778-80baxwgc	74	6	insufficient	insufficient	JJ
cord-285778-80baxwgc	74	7	to	to	TO
cord-285778-80baxwgc	74	8	control	control	VB
cord-285778-80baxwgc	74	9	the	the	DT
cord-285778-80baxwgc	74	10	situation	situation	NN
cord-285778-80baxwgc	74	11	and	and	CC
cord-285778-80baxwgc	74	12	restore	restore	VB
cord-285778-80baxwgc	74	13	homeostasis	homeostasis	NN
cord-285778-80baxwgc	74	14	,	,	,
cord-285778-80baxwgc	74	15	as	as	IN
cord-285778-80baxwgc	74	16	is	be	VBZ
cord-285778-80baxwgc	74	17	often	often	RB
cord-285778-80baxwgc	74	18	the	the	DT
cord-285778-80baxwgc	74	19	case	case	NN
cord-285778-80baxwgc	74	20	with	with	IN
cord-285778-80baxwgc	74	21	infection	infection	NN
cord-285778-80baxwgc	74	22	by	by	IN
cord-285778-80baxwgc	74	23	a	a	DT
cord-285778-80baxwgc	74	24	rapidly	rapidly	RB
cord-285778-80baxwgc	74	25	replicating	replicate	VBG
cord-285778-80baxwgc	74	26	pathogen	pathogen	NN
cord-285778-80baxwgc	74	27	,	,	,
cord-285778-80baxwgc	74	28	is	be	VBZ
cord-285778-80baxwgc	74	29	an	an	DT
cord-285778-80baxwgc	74	30	adaptive	adaptive	JJ
cord-285778-80baxwgc	74	31	response	response	NN
cord-285778-80baxwgc	74	32	mounted	mount	VBD
cord-285778-80baxwgc	74	33	.	.	.
cord-285778-80baxwgc	75	1	Together	together	RB
cord-285778-80baxwgc	75	2	,	,	,
cord-285778-80baxwgc	75	3	the	the	DT
cord-285778-80baxwgc	75	4	innate	innate	JJ
cord-285778-80baxwgc	75	5	and	and	CC
cord-285778-80baxwgc	75	6	adaptive	adaptive	JJ
cord-285778-80baxwgc	75	7	immune	immune	JJ
cord-285778-80baxwgc	75	8	responses	response	NNS
cord-285778-80baxwgc	75	9	allow	allow	VBP
cord-285778-80baxwgc	75	10	a	a	DT
cord-285778-80baxwgc	75	11	seamless	seamless	JJ
cord-285778-80baxwgc	75	12	escalation	escalation	NN
cord-285778-80baxwgc	75	13	of	of	IN
cord-285778-80baxwgc	75	14	countermeasures	countermeasure	NNS
cord-285778-80baxwgc	75	15	that	that	WDT
cord-285778-80baxwgc	75	16	maintain	maintain	VBP
cord-285778-80baxwgc	75	17	homeostasis	homeostasis	NN
cord-285778-80baxwgc	75	18	in	in	IN
cord-285778-80baxwgc	75	19	the	the	DT
cord-285778-80baxwgc	75	20	face	face	NN
cord-285778-80baxwgc	75	21	of	of	IN
cord-285778-80baxwgc	75	22	cellular	cellular	JJ
cord-285778-80baxwgc	75	23	aging	aging	NN
cord-285778-80baxwgc	75	24	,	,	,
cord-285778-80baxwgc	75	25	tissue	tissue	NN
cord-285778-80baxwgc	75	26	trauma	trauma	NN
cord-285778-80baxwgc	75	27	and/or	and/or	CC
cord-285778-80baxwgc	75	28	pathogen	pathogen	NN
cord-285778-80baxwgc	75	29	infection	infection	NN
cord-285778-80baxwgc	75	30	.	.	.
cord-285778-80baxwgc	76	1	What	what	WP
cord-285778-80baxwgc	76	2	exactly	exactly	RB
cord-285778-80baxwgc	76	3	triggers	trigger	VBZ
cord-285778-80baxwgc	76	4	the	the	DT
cord-285778-80baxwgc	76	5	initial	initial	JJ
cord-285778-80baxwgc	76	6	response	response	NN
cord-285778-80baxwgc	76	7	by	by	IN
cord-285778-80baxwgc	76	8	the	the	DT
cord-285778-80baxwgc	76	9	innate	innate	JJ
cord-285778-80baxwgc	76	10	system	system	NN
cord-285778-80baxwgc	76	11	?	?	.
cord-285778-80baxwgc	77	1	In	in	IN
cord-285778-80baxwgc	77	2	a	a	DT
cord-285778-80baxwgc	77	3	word	word	NN
cord-285778-80baxwgc	77	4	:	:	:
cord-285778-80baxwgc	77	5	recognition	recognition	NN
cord-285778-80baxwgc	77	6	.	.	.
cord-285778-80baxwgc	78	1	Wherever	wherever	WRB
cord-285778-80baxwgc	78	2	cells	cell	NNS
cord-285778-80baxwgc	78	3	are	be	VBP
cord-285778-80baxwgc	78	4	damaged	damage	VBN
cord-285778-80baxwgc	78	5	or	or	CC
cord-285778-80baxwgc	78	6	dying	die	VBG
cord-285778-80baxwgc	78	7	-	-	:
cord-285778-80baxwgc	78	8	either	either	CC
cord-285778-80baxwgc	78	9	in	in	IN
cord-285778-80baxwgc	78	10	the	the	DT
cord-285778-80baxwgc	78	11	presence	presence	NN
cord-285778-80baxwgc	78	12	or	or	CC
cord-285778-80baxwgc	78	13	absence	absence	NN
cord-285778-80baxwgc	78	14	of	of	IN
cord-285778-80baxwgc	78	15	infection	infection	NN
cord-285778-80baxwgc	78	16	-	-	HYPH
cord-285778-80baxwgc	78	17	particular	particular	JJ
cord-285778-80baxwgc	78	18	host	host	NN
cord-285778-80baxwgc	78	19	macromolecules	macromolecule	NNS
cord-285778-80baxwgc	78	20	are	be	VBP
cord-285778-80baxwgc	78	21	released	release	VBN
cord-285778-80baxwgc	78	22	into	into	IN
cord-285778-80baxwgc	78	23	the	the	DT
cord-285778-80baxwgc	78	24	extracellular	extracellular	JJ
cord-285778-80baxwgc	78	25	milieu	milieu	NN
cord-285778-80baxwgc	78	26	or	or	CC
cord-285778-80baxwgc	78	27	become	become	VBP
cord-285778-80baxwgc	78	28	accessible	accessible	JJ
cord-285778-80baxwgc	78	29	on	on	IN
cord-285778-80baxwgc	78	30	the	the	DT
cord-285778-80baxwgc	78	31	surface	surface	NN
cord-285778-80baxwgc	78	32	of	of	IN
cord-285778-80baxwgc	78	33	damaged	damaged	JJ
cord-285778-80baxwgc	78	34	cells	cell	NNS
cord-285778-80baxwgc	78	35	or	or	CC
cord-285778-80baxwgc	78	36	in	in	IN
cord-285778-80baxwgc	78	37	cellular	cellular	JJ
cord-285778-80baxwgc	78	38	debris	debris	NN
cord-285778-80baxwgc	78	39	.	.	.
cord-285778-80baxwgc	79	1	These	these	DT
cord-285778-80baxwgc	79	2	molecules	molecule	NNS
cord-285778-80baxwgc	79	3	are	be	VBP
cord-285778-80baxwgc	79	4	called	call	VBN
cord-285778-80baxwgc	79	5	damage	damage	NN
cord-285778-80baxwgc	79	6	-	-	HYPH
cord-285778-80baxwgc	79	7	associated	associate	VBN
cord-285778-80baxwgc	79	8	molecular	molecular	JJ
cord-285778-80baxwgc	79	9	patterns	pattern	NNS
cord-285778-80baxwgc	79	10	(	(	-LRB-
cord-285778-80baxwgc	79	11	DAMPs	damp	NNS
cord-285778-80baxwgc	79	12	)	)	-RRB-
cord-285778-80baxwgc	79	13	.	.	.
cord-285778-80baxwgc	80	1	When	when	WRB
cord-285778-80baxwgc	80	2	a	a	DT
cord-285778-80baxwgc	80	3	pathogen	pathogen	NN
cord-285778-80baxwgc	80	4	attacks	attack	NNS
cord-285778-80baxwgc	80	5	,	,	,
cord-285778-80baxwgc	80	6	it	-PRON-	PRP
cord-285778-80baxwgc	80	7	furnishes	furnish	VBZ
cord-285778-80baxwgc	80	8	common	common	JJ
cord-285778-80baxwgc	80	9	molecular	molecular	JJ
cord-285778-80baxwgc	80	10	structures	structure	NNS
cord-285778-80baxwgc	80	11	on	on	IN
cord-285778-80baxwgc	80	12	its	-PRON-	PRP$
cord-285778-80baxwgc	80	13	own	own	JJ
cord-285778-80baxwgc	80	14	surface	surface	NN
cord-285778-80baxwgc	80	15	,	,	,
cord-285778-80baxwgc	80	16	or	or	CC
cord-285778-80baxwgc	80	17	on	on	IN
cord-285778-80baxwgc	80	18	the	the	DT
cord-285778-80baxwgc	80	19	surface	surface	NN
cord-285778-80baxwgc	80	20	of	of	IN
cord-285778-80baxwgc	80	21	cells	cell	NNS
cord-285778-80baxwgc	80	22	it	-PRON-	PRP
cord-285778-80baxwgc	80	23	has	have	VBZ
cord-285778-80baxwgc	80	24	infected	infect	VBN
cord-285778-80baxwgc	80	25	,	,	,
cord-285778-80baxwgc	80	26	or	or	CC
cord-285778-80baxwgc	80	27	as	as	IN
cord-285778-80baxwgc	80	28	part	part	NN
cord-285778-80baxwgc	80	29	of	of	IN
cord-285778-80baxwgc	80	30	products	product	NNS
cord-285778-80baxwgc	80	31	it	-PRON-	PRP
cord-285778-80baxwgc	80	32	synthesizes	synthesize	VBZ
cord-285778-80baxwgc	80	33	.	.	.
cord-285778-80baxwgc	81	1	These	these	DT
cord-285778-80baxwgc	81	2	structures	structure	NNS
cord-285778-80baxwgc	81	3	are	be	VBP
cord-285778-80baxwgc	81	4	called	call	VBN
cord-285778-80baxwgc	81	5	pathogen	pathogen	NN
cord-285778-80baxwgc	81	6	-	-	HYPH
cord-285778-80baxwgc	81	7	associated	associate	VBN
cord-285778-80baxwgc	81	8	molecular	molecular	JJ
cord-285778-80baxwgc	81	9	patterns	pattern	NNS
cord-285778-80baxwgc	81	10	(	(	-LRB-
cord-285778-80baxwgc	81	11	PAMPs	pamp	NNS
cord-285778-80baxwgc	81	12	)	)	-RRB-
cord-285778-80baxwgc	81	13	.	.	.
cord-285778-80baxwgc	82	1	Cell	cell	NN
cord-285778-80baxwgc	82	2	damage	damage	NN
cord-285778-80baxwgc	82	3	or	or	CC
cord-285778-80baxwgc	82	4	death	death	NN
cord-285778-80baxwgc	82	5	in	in	IN
cord-285778-80baxwgc	82	6	the	the	DT
cord-285778-80baxwgc	82	7	absence	absence	NN
cord-285778-80baxwgc	82	8	of	of	IN
cord-285778-80baxwgc	82	9	a	a	DT
cord-285778-80baxwgc	82	10	pathogen	pathogen	NN
cord-285778-80baxwgc	82	11	gives	give	VBZ
cord-285778-80baxwgc	82	12	rise	rise	NN
cord-285778-80baxwgc	82	13	to	to	IN
cord-285778-80baxwgc	82	14	DAMPs	damp	NNS
cord-285778-80baxwgc	82	15	only	only	RB
cord-285778-80baxwgc	82	16	,	,	,
cord-285778-80baxwgc	82	17	but	but	CC
cord-285778-80baxwgc	82	18	both	both	DT
cord-285778-80baxwgc	82	19	DAMPs	damp	NNS
cord-285778-80baxwgc	82	20	and	and	CC
cord-285778-80baxwgc	82	21	PAMPs	pamp	NNS
cord-285778-80baxwgc	82	22	will	will	MD
cord-285778-80baxwgc	82	23	be	be	VB
cord-285778-80baxwgc	82	24	present	present	JJ
cord-285778-80baxwgc	82	25	when	when	WRB
cord-285778-80baxwgc	82	26	a	a	DT
cord-285778-80baxwgc	82	27	pathogen	pathogen	NN
cord-285778-80baxwgc	82	28	invades	invade	VBZ
cord-285778-80baxwgc	82	29	(	(	-LRB-
cord-285778-80baxwgc	82	30	Fig	Fig	NNP
cord-285778-80baxwgc	82	31	.	.	NNP
cord-285778-80baxwgc	82	32	1	1	CD
cord-285778-80baxwgc	82	33	-	-	SYM
cord-285778-80baxwgc	82	34	2	2	CD
cord-285778-80baxwgc	82	35	)	)	-RRB-
cord-285778-80baxwgc	82	36	.	.	.
cord-285778-80baxwgc	83	1	It	-PRON-	PRP
cord-285778-80baxwgc	83	2	is	be	VBZ
cord-285778-80baxwgc	83	3	the	the	DT
cord-285778-80baxwgc	83	4	recognition	recognition	NN
cord-285778-80baxwgc	83	5	of	of	IN
cord-285778-80baxwgc	83	6	DAMPs	damp	NNS
cord-285778-80baxwgc	83	7	and	and	CC
cord-285778-80baxwgc	83	8	PAMPs	pamp	NNS
cord-285778-80baxwgc	83	9	by	by	IN
cord-285778-80baxwgc	83	10	innate	innate	JJ
cord-285778-80baxwgc	83	11	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	83	12	that	that	WDT
cord-285778-80baxwgc	83	13	initiates	initiate	VBZ
cord-285778-80baxwgc	83	14	innate	innate	JJ
cord-285778-80baxwgc	83	15	responses	response	NNS
cord-285778-80baxwgc	83	16	.	.	.
cord-285778-80baxwgc	84	1	DAMPs	damp	NNS
cord-285778-80baxwgc	84	2	and	and	CC
cord-285778-80baxwgc	84	3	PAMPs	pamp	NNS
cord-285778-80baxwgc	84	4	are	be	VBP
cord-285778-80baxwgc	84	5	recognized	recognize	VBN
cord-285778-80baxwgc	84	6	by	by	IN
cord-285778-80baxwgc	84	7	host	host	NN
cord-285778-80baxwgc	84	8	proteins	protein	NNS
cord-285778-80baxwgc	84	9	called	call	VBN
cord-285778-80baxwgc	84	10	pattern	pattern	NN
cord-285778-80baxwgc	84	11	recognition	recognition	NN
cord-285778-80baxwgc	84	12	molecules	molecule	NNS
cord-285778-80baxwgc	84	13	(	(	-LRB-
cord-285778-80baxwgc	84	14	PRMs	PRMs	NNP
cord-285778-80baxwgc	84	15	)	)	-RRB-
cord-285778-80baxwgc	84	16	,	,	,
cord-285778-80baxwgc	84	17	most	most	JJS
cord-285778-80baxwgc	84	18	of	of	IN
cord-285778-80baxwgc	84	19	which	which	WDT
cord-285778-80baxwgc	84	20	are	be	VBP
cord-285778-80baxwgc	84	21	expressed	express	VBN
cord-285778-80baxwgc	84	22	by	by	IN
cord-285778-80baxwgc	84	23	innate	innate	JJ
cord-285778-80baxwgc	84	24	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	84	25	.	.	.
cord-285778-80baxwgc	85	1	There	there	EX
cord-285778-80baxwgc	85	2	is	be	VBZ
cord-285778-80baxwgc	85	3	not	not	RB
cord-285778-80baxwgc	85	4	a	a	DT
cord-285778-80baxwgc	85	5	large	large	JJ
cord-285778-80baxwgc	85	6	array	array	NN
cord-285778-80baxwgc	85	7	of	of	IN
cord-285778-80baxwgc	85	8	different	different	JJ
cord-285778-80baxwgc	85	9	PRMs	prm	NNS
cord-285778-80baxwgc	85	10	,	,	,
cord-285778-80baxwgc	85	11	meaning	mean	VBG
cord-285778-80baxwgc	85	12	that	that	IN
cord-285778-80baxwgc	85	13	there	there	EX
cord-285778-80baxwgc	85	14	is	be	VBZ
cord-285778-80baxwgc	85	15	a	a	DT
cord-285778-80baxwgc	85	16	limited	limited	JJ
cord-285778-80baxwgc	85	17	repertoire	repertoire	NN
cord-285778-80baxwgc	85	18	of	of	IN
cord-285778-80baxwgc	85	19	molecular	molecular	JJ
cord-285778-80baxwgc	85	20	patterns	pattern	NNS
cord-285778-80baxwgc	85	21	that	that	WDT
cord-285778-80baxwgc	85	22	can	can	MD
cord-285778-80baxwgc	85	23	be	be	VB
cord-285778-80baxwgc	85	24	recognized	recognize	VBN
cord-285778-80baxwgc	85	25	.	.	.
cord-285778-80baxwgc	86	1	However	however	RB
cord-285778-80baxwgc	86	2	,	,	,
cord-285778-80baxwgc	86	3	each	each	DT
cord-285778-80baxwgc	86	4	PRM	PRM	NNP
cord-285778-80baxwgc	86	5	recognizes	recognize	VBZ
cord-285778-80baxwgc	86	6	a	a	DT
cord-285778-80baxwgc	86	7	DAMP	damp	JJ
cord-285778-80baxwgc	86	8	or	or	CC
cord-285778-80baxwgc	86	9	PAMP	pamp	NN
cord-285778-80baxwgc	86	10	that	that	WDT
cord-285778-80baxwgc	86	11	is	be	VBZ
cord-285778-80baxwgc	86	12	shared	share	VBN
cord-285778-80baxwgc	86	13	by	by	IN
cord-285778-80baxwgc	86	14	many	many	JJ
cord-285778-80baxwgc	86	15	different	different	JJ
cord-285778-80baxwgc	86	16	damaged	damage	VBN
cord-285778-80baxwgc	86	17	cells	cell	NNS
cord-285778-80baxwgc	86	18	or	or	CC
cord-285778-80baxwgc	86	19	pathogens	pathogen	NNS
cord-285778-80baxwgc	86	20	.	.	.
cord-285778-80baxwgc	87	1	Thus	thus	RB
cord-285778-80baxwgc	87	2	,	,	,
cord-285778-80baxwgc	87	3	PRMs	prm	NNS
cord-285778-80baxwgc	87	4	give	give	VBP
cord-285778-80baxwgc	87	5	the	the	DT
cord-285778-80baxwgc	87	6	innate	innate	JJ
cord-285778-80baxwgc	87	7	immune	immune	JJ
cord-285778-80baxwgc	87	8	response	response	NN
cord-285778-80baxwgc	87	9	the	the	DT
cord-285778-80baxwgc	87	10	property	property	NN
cord-285778-80baxwgc	87	11	of	of	IN
cord-285778-80baxwgc	87	12	broad	broad	JJ
cord-285778-80baxwgc	87	13	recognition	recognition	NN
cord-285778-80baxwgc	87	14	.	.	.
cord-285778-80baxwgc	88	1	Furthermore	furthermore	RB
cord-285778-80baxwgc	88	2	,	,	,
cord-285778-80baxwgc	88	3	because	because	IN
cord-285778-80baxwgc	88	4	innate	innate	JJ
cord-285778-80baxwgc	88	5	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	88	6	expressing	express	VBG
cord-285778-80baxwgc	88	7	PRMs	prm	NNS
cord-285778-80baxwgc	88	8	are	be	VBP
cord-285778-80baxwgc	88	9	present	present	JJ
cord-285778-80baxwgc	88	10	in	in	IN
cord-285778-80baxwgc	88	11	large	large	JJ
cord-285778-80baxwgc	88	12	numbers	number	NNS
cord-285778-80baxwgc	88	13	,	,	,
cord-285778-80baxwgc	88	14	these	these	DT
cord-285778-80baxwgc	88	15	cells	cell	NNS
cord-285778-80baxwgc	88	16	do	do	VBP
cord-285778-80baxwgc	88	17	n't	not	RB
cord-285778-80baxwgc	88	18	need	need	VB
cord-285778-80baxwgc	88	19	to	to	TO
cord-285778-80baxwgc	88	20	multiply	multiply	VB
cord-285778-80baxwgc	88	21	to	to	IN
cord-285778-80baxwgc	88	22	work	work	NN
cord-285778-80baxwgc	88	23	effectively	effectively	RB
cord-285778-80baxwgc	88	24	:	:	:
cord-285778-80baxwgc	88	25	the	the	DT
cord-285778-80baxwgc	88	26	response	response	NN
cord-285778-80baxwgc	88	27	is	be	VBZ
cord-285778-80baxwgc	88	28	immediate	immediate	JJ
cord-285778-80baxwgc	88	29	.	.	.
cord-285778-80baxwgc	89	1	Finally	finally	RB
cord-285778-80baxwgc	89	2	,	,	,
cord-285778-80baxwgc	89	3	because	because	IN
cord-285778-80baxwgc	89	4	innate	innate	JJ
cord-285778-80baxwgc	89	5	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	89	6	are	be	VBP
cord-285778-80baxwgc	89	7	activated	activate	VBN
cord-285778-80baxwgc	89	8	but	but	CC
cord-285778-80baxwgc	89	9	do	do	VBP
cord-285778-80baxwgc	89	10	n't	not	RB
cord-285778-80baxwgc	89	11	multiply	multiply	VB
cord-285778-80baxwgc	89	12	in	in	IN
cord-285778-80baxwgc	89	13	response	response	NN
cord-285778-80baxwgc	89	14	to	to	IN
cord-285778-80baxwgc	89	15	engagement	engagement	NN
cord-285778-80baxwgc	89	16	of	of	IN
cord-285778-80baxwgc	89	17	their	-PRON-	PRP$
cord-285778-80baxwgc	89	18	PRMs	prm	NNS
cord-285778-80baxwgc	89	19	,	,	,
cord-285778-80baxwgc	89	20	the	the	DT
cord-285778-80baxwgc	89	21	speed	speed	NN
cord-285778-80baxwgc	89	22	and	and	CC
cord-285778-80baxwgc	89	23	strength	strength	NN
cord-285778-80baxwgc	89	24	of	of	IN
cord-285778-80baxwgc	89	25	their	-PRON-	PRP$
cord-285778-80baxwgc	89	26	response	response	NN
cord-285778-80baxwgc	89	27	is	be	VBZ
cord-285778-80baxwgc	89	28	exactly	exactly	RB
cord-285778-80baxwgc	89	29	the	the	DT
cord-285778-80baxwgc	89	30	same	same	JJ
cord-285778-80baxwgc	89	31	upon	upon	IN
cord-285778-80baxwgc	89	32	a	a	DT
cord-285778-80baxwgc	89	33	second	second	JJ
cord-285778-80baxwgc	89	34	exposure	exposure	NN
cord-285778-80baxwgc	89	35	to	to	IN
cord-285778-80baxwgc	89	36	the	the	DT
cord-285778-80baxwgc	89	37	same	same	JJ
cord-285778-80baxwgc	89	38	pathogen	pathogen	NN
cord-285778-80baxwgc	89	39	or	or	CC
cord-285778-80baxwgc	89	40	type	type	NN
cord-285778-80baxwgc	89	41	of	of	IN
cord-285778-80baxwgc	89	42	damage	damage	NN
cord-285778-80baxwgc	89	43	.	.	.
cord-285778-80baxwgc	90	1	The	the	DT
cord-285778-80baxwgc	90	2	result	result	NN
cord-285778-80baxwgc	90	3	is	be	VBZ
cord-285778-80baxwgc	90	4	a	a	DT
cord-285778-80baxwgc	90	5	response	response	NN
cord-285778-80baxwgc	90	6	that	that	WDT
cord-285778-80baxwgc	90	7	is	be	VBZ
cord-285778-80baxwgc	90	8	said	say	VBN
cord-285778-80baxwgc	90	9	to	to	TO
cord-285778-80baxwgc	90	10	have	have	VB
cord-285778-80baxwgc	90	11	no	no	DT
cord-285778-80baxwgc	90	12	memory	memory	NN
cord-285778-80baxwgc	90	13	.	.	.
cord-285778-80baxwgc	91	1	Recognition	recognition	NN
cord-285778-80baxwgc	91	2	is	be	VBZ
cord-285778-80baxwgc	91	3	also	also	RB
cord-285778-80baxwgc	91	4	the	the	DT
cord-285778-80baxwgc	91	5	key	key	NN
cord-285778-80baxwgc	91	6	to	to	IN
cord-285778-80baxwgc	91	7	initiating	initiate	VBG
cord-285778-80baxwgc	91	8	the	the	DT
cord-285778-80baxwgc	91	9	adaptive	adaptive	JJ
cord-285778-80baxwgc	91	10	immune	immune	JJ
cord-285778-80baxwgc	91	11	response	response	NN
cord-285778-80baxwgc	91	12	,	,	,
cord-285778-80baxwgc	91	13	but	but	CC
cord-285778-80baxwgc	91	14	there	there	EX
cord-285778-80baxwgc	91	15	are	be	VBP
cord-285778-80baxwgc	91	16	important	important	JJ
cord-285778-80baxwgc	91	17	differences	difference	NNS
cord-285778-80baxwgc	91	18	.	.	.
cord-285778-80baxwgc	92	1	In	in	IN
cord-285778-80baxwgc	92	2	contrast	contrast	NN
cord-285778-80baxwgc	92	3	to	to	IN
cord-285778-80baxwgc	92	4	the	the	DT
cord-285778-80baxwgc	92	5	broad	broad	JJ
cord-285778-80baxwgc	92	6	recognition	recognition	NN
cord-285778-80baxwgc	92	7	of	of	IN
cord-285778-80baxwgc	92	8	the	the	DT
cord-285778-80baxwgc	92	9	PRMs	prm	NNS
cord-285778-80baxwgc	92	10	mediating	mediate	VBG
cord-285778-80baxwgc	92	11	the	the	DT
cord-285778-80baxwgc	92	12	innate	innate	JJ
cord-285778-80baxwgc	92	13	response	response	NN
cord-285778-80baxwgc	92	14	,	,	,
cord-285778-80baxwgc	92	15	the	the	DT
cord-285778-80baxwgc	92	16	receptors	receptor	NNS
cord-285778-80baxwgc	92	17	expressed	express	VBN
cord-285778-80baxwgc	92	18	by	by	IN
cord-285778-80baxwgc	92	19	the	the	DT
cord-285778-80baxwgc	92	20	cells	cell	NNS
cord-285778-80baxwgc	92	21	participating	participate	VBG
cord-285778-80baxwgc	92	22	in	in	IN
cord-285778-80baxwgc	92	23	the	the	DT
cord-285778-80baxwgc	92	24	adaptive	adaptive	JJ
cord-285778-80baxwgc	92	25	response	response	NN
cord-285778-80baxwgc	92	26	(	(	-LRB-
cord-285778-80baxwgc	92	27	adaptive	adaptive	JJ
cord-285778-80baxwgc	92	28	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	92	29	)	)	-RRB-
cord-285778-80baxwgc	92	30	are	be	VBP
cord-285778-80baxwgc	92	31	equipped	equip	VBN
cord-285778-80baxwgc	92	32	with	with	IN
cord-285778-80baxwgc	92	33	receptors	receptor	NNS
cord-285778-80baxwgc	92	34	that	that	WDT
cord-285778-80baxwgc	92	35	recognize	recognize	VBP
cord-285778-80baxwgc	92	36	unique	unique	JJ
cord-285778-80baxwgc	92	37	molecular	molecular	JJ
cord-285778-80baxwgc	92	38	structures	structure	NNS
cord-285778-80baxwgc	92	39	on	on	IN
cord-285778-80baxwgc	92	40	pathogens	pathogen	NNS
cord-285778-80baxwgc	92	41	.	.	.
cord-285778-80baxwgc	93	1	These	these	DT
cord-285778-80baxwgc	93	2	unique	unique	JJ
cord-285778-80baxwgc	93	3	structures	structure	NNS
cord-285778-80baxwgc	93	4	are	be	VBP
cord-285778-80baxwgc	93	5	called	call	VBN
cord-285778-80baxwgc	93	6	antigens	antigen	NNS
cord-285778-80baxwgc	93	7	,	,	,
cord-285778-80baxwgc	93	8	and	and	CC
cord-285778-80baxwgc	93	9	the	the	DT
cord-285778-80baxwgc	93	10	receptors	receptor	NNS
cord-285778-80baxwgc	93	11	that	that	WDT
cord-285778-80baxwgc	93	12	recognize	recognize	VBP
cord-285778-80baxwgc	93	13	them	-PRON-	PRP
cord-285778-80baxwgc	93	14	are	be	VBP
cord-285778-80baxwgc	93	15	antigen	antigen	NN
cord-285778-80baxwgc	93	16	receptors	receptor	NNS
cord-285778-80baxwgc	93	17	.	.	.
cord-285778-80baxwgc	94	1	Together	together	RB
cord-285778-80baxwgc	94	2	as	as	IN
cord-285778-80baxwgc	94	3	a	a	DT
cord-285778-80baxwgc	94	4	population	population	NN
cord-285778-80baxwgc	94	5	,	,	,
cord-285778-80baxwgc	94	6	adaptive	adaptive	JJ
cord-285778-80baxwgc	94	7	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	94	8	express	express	VBP
cord-285778-80baxwgc	94	9	a	a	DT
cord-285778-80baxwgc	94	10	vast	vast	JJ
cord-285778-80baxwgc	94	11	array	array	NN
cord-285778-80baxwgc	94	12	of	of	IN
cord-285778-80baxwgc	94	13	antigen	antigen	NN
cord-285778-80baxwgc	94	14	receptors	receptor	NNS
cord-285778-80baxwgc	94	15	capable	capable	JJ
cord-285778-80baxwgc	94	16	of	of	IN
cord-285778-80baxwgc	94	17	recognizing	recognize	VBG
cord-285778-80baxwgc	94	18	almost	almost	RB
cord-285778-80baxwgc	94	19	any	any	DT
cord-285778-80baxwgc	94	20	structure	structure	NN
cord-285778-80baxwgc	94	21	,	,	,
cord-285778-80baxwgc	94	22	meaning	mean	VBG
cord-285778-80baxwgc	94	23	that	that	IN
cord-285778-80baxwgc	94	24	they	-PRON-	PRP
cord-285778-80baxwgc	94	25	represent	represent	VBP
cord-285778-80baxwgc	94	26	a	a	DT
cord-285778-80baxwgc	94	27	diverse	diverse	JJ
cord-285778-80baxwgc	94	28	repertoire	repertoire	NN
cord-285778-80baxwgc	94	29	of	of	IN
cord-285778-80baxwgc	94	30	antigen	antigen	NN
cord-285778-80baxwgc	94	31	specificities	specificity	NNS
cord-285778-80baxwgc	94	32	.	.	.
cord-285778-80baxwgc	95	1	However	however	RB
cord-285778-80baxwgc	95	2	,	,	,
cord-285778-80baxwgc	95	3	the	the	DT
cord-285778-80baxwgc	95	4	antigen	antigen	NN
cord-285778-80baxwgc	95	5	receptor	receptor	NN
cord-285778-80baxwgc	95	6	of	of	IN
cord-285778-80baxwgc	95	7	any	any	DT
cord-285778-80baxwgc	95	8	one	one	CD
cord-285778-80baxwgc	95	9	adaptive	adaptive	JJ
cord-285778-80baxwgc	95	10	leukocyte	leukocyte	NN
cord-285778-80baxwgc	95	11	binds	bind	VBZ
cord-285778-80baxwgc	95	12	to	to	IN
cord-285778-80baxwgc	95	13	an	an	DT
cord-285778-80baxwgc	95	14	antigen	antigen	NN
cord-285778-80baxwgc	95	15	exclusive	exclusive	JJ
cord-285778-80baxwgc	95	16	to	to	IN
cord-285778-80baxwgc	95	17	a	a	DT
cord-285778-80baxwgc	95	18	single	single	JJ
cord-285778-80baxwgc	95	19	type	type	NN
cord-285778-80baxwgc	95	20	of	of	IN
cord-285778-80baxwgc	95	21	pathogen	pathogen	NN
cord-285778-80baxwgc	95	22	.	.	.
cord-285778-80baxwgc	96	1	Thus	thus	RB
cord-285778-80baxwgc	96	2	,	,	,
cord-285778-80baxwgc	96	3	antigen	antigen	NN
cord-285778-80baxwgc	96	4	receptors	receptor	NNS
cord-285778-80baxwgc	96	5	have	have	VBP
cord-285778-80baxwgc	96	6	the	the	DT
cord-285778-80baxwgc	96	7	property	property	NN
cord-285778-80baxwgc	96	8	of	of	IN
cord-285778-80baxwgc	96	9	specific	specific	JJ
cord-285778-80baxwgc	96	10	recognition	recognition	NN
cord-285778-80baxwgc	96	11	.	.	.
cord-285778-80baxwgc	97	1	Because	because	IN
cord-285778-80baxwgc	97	2	adaptive	adaptive	JJ
cord-285778-80baxwgc	97	3	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	97	4	are	be	VBP
cord-285778-80baxwgc	97	5	very	very	RB
cord-285778-80baxwgc	97	6	few	few	JJ
cord-285778-80baxwgc	97	7	in	in	IN
cord-285778-80baxwgc	97	8	number	number	NN
cord-285778-80baxwgc	97	9	,	,	,
cord-285778-80baxwgc	97	10	these	these	DT
cord-285778-80baxwgc	97	11	cells	cell	NNS
cord-285778-80baxwgc	97	12	must	must	MD
cord-285778-80baxwgc	97	13	proliferate	proliferate	VB
cord-285778-80baxwgc	97	14	and	and	CC
cord-285778-80baxwgc	97	15	expand	expand	VB
cord-285778-80baxwgc	97	16	their	-PRON-	PRP$
cord-285778-80baxwgc	97	17	ranks	rank	NNS
cord-285778-80baxwgc	97	18	after	after	IN
cord-285778-80baxwgc	97	19	receptor	receptor	NN
cord-285778-80baxwgc	97	20	engagement	engagement	NN
cord-285778-80baxwgc	97	21	before	before	IN
cord-285778-80baxwgc	97	22	they	-PRON-	PRP
cord-285778-80baxwgc	97	23	can	can	MD
cord-285778-80baxwgc	97	24	be	be	VB
cord-285778-80baxwgc	97	25	effective	effective	JJ
cord-285778-80baxwgc	97	26	:	:	:
cord-285778-80baxwgc	97	27	the	the	DT
cord-285778-80baxwgc	97	28	response	response	NN
cord-285778-80baxwgc	97	29	is	be	VBZ
cord-285778-80baxwgc	97	30	delayed	delay	VBN
cord-285778-80baxwgc	97	31	.	.	.
cord-285778-80baxwgc	98	1	In	in	IN
cord-285778-80baxwgc	98	2	addition	addition	NN
cord-285778-80baxwgc	98	3	,	,	,
cord-285778-80baxwgc	98	4	after	after	IN
cord-285778-80baxwgc	98	5	adaptive	adaptive	JJ
cord-285778-80baxwgc	98	6	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	98	7	proliferate	proliferate	VBP
cord-285778-80baxwgc	98	8	and	and	CC
cord-285778-80baxwgc	98	9	act	act	VBP
cord-285778-80baxwgc	98	10	to	to	TO
cord-285778-80baxwgc	98	11	eliminate	eliminate	VB
cord-285778-80baxwgc	98	12	the	the	DT
cord-285778-80baxwgc	98	13	pathogen	pathogen	NN
cord-285778-80baxwgc	98	14	,	,	,
cord-285778-80baxwgc	98	15	some	some	DT
cord-285778-80baxwgc	98	16	of	of	IN
cord-285778-80baxwgc	98	17	these	these	DT
cord-285778-80baxwgc	98	18	cells	cell	NNS
cord-285778-80baxwgc	98	19	become	become	VBP
cord-285778-80baxwgc	98	20	long	long	RB
cord-285778-80baxwgc	98	21	-	-	HYPH
cord-285778-80baxwgc	98	22	lived	live	VBN
cord-285778-80baxwgc	98	23	so	so	IN
cord-285778-80baxwgc	98	24	that	that	IN
cord-285778-80baxwgc	98	25	the	the	DT
cord-285778-80baxwgc	98	26	speed	speed	NN
cord-285778-80baxwgc	98	27	and	and	CC
cord-285778-80baxwgc	98	28	strength	strength	NN
cord-285778-80baxwgc	98	29	of	of	IN
cord-285778-80baxwgc	98	30	the	the	DT
cord-285778-80baxwgc	98	31	adaptive	adaptive	JJ
cord-285778-80baxwgc	98	32	response	response	NN
cord-285778-80baxwgc	98	33	is	be	VBZ
cord-285778-80baxwgc	98	34	increased	increase	VBN
cord-285778-80baxwgc	98	35	upon	upon	IN
cord-285778-80baxwgc	98	36	a	a	DT
cord-285778-80baxwgc	98	37	subsequent	subsequent	JJ
cord-285778-80baxwgc	98	38	exposure	exposure	NN
cord-285778-80baxwgc	98	39	to	to	IN
cord-285778-80baxwgc	98	40	the	the	DT
cord-285778-80baxwgc	98	41	same	same	JJ
cord-285778-80baxwgc	98	42	pathogen	pathogen	NN
cord-285778-80baxwgc	98	43	.	.	.
cord-285778-80baxwgc	99	1	The	the	DT
cord-285778-80baxwgc	99	2	adaptive	adaptive	JJ
cord-285778-80baxwgc	99	3	response	response	NN
cord-285778-80baxwgc	99	4	is	be	VBZ
cord-285778-80baxwgc	99	5	thus	thus	RB
cord-285778-80baxwgc	99	6	said	say	VBN
cord-285778-80baxwgc	99	7	to	to	TO
cord-285778-80baxwgc	99	8	have	have	VB
cord-285778-80baxwgc	99	9	memory	memory	NN
cord-285778-80baxwgc	99	10	.	.	.
cord-285778-80baxwgc	100	1	The	the	DT
cord-285778-80baxwgc	100	2	distinguishing	distinguishing	JJ
cord-285778-80baxwgc	100	3	features	feature	NNS
cord-285778-80baxwgc	100	4	of	of	IN
cord-285778-80baxwgc	100	5	the	the	DT
cord-285778-80baxwgc	100	6	innate	innate	JJ
cord-285778-80baxwgc	100	7	and	and	CC
cord-285778-80baxwgc	100	8	adaptive	adaptive	JJ
cord-285778-80baxwgc	100	9	responses	response	NNS
cord-285778-80baxwgc	100	10	are	be	VBP
cord-285778-80baxwgc	100	11	summarized	summarize	VBN
cord-285778-80baxwgc	100	12	in	in	IN
cord-285778-80baxwgc	100	13	Table	Table	NNP
cord-285778-80baxwgc	100	14	1	1	CD
cord-285778-80baxwgc	100	15	-1	-1	NN
cord-285778-80baxwgc	100	16	.	.	.
cord-285778-80baxwgc	101	1	A	a	DT
cord-285778-80baxwgc	101	2	DAMP	damp	NN
cord-285778-80baxwgc	101	3	is	be	VBZ
cord-285778-80baxwgc	101	4	a	a	DT
cord-285778-80baxwgc	101	5	common	common	JJ
cord-285778-80baxwgc	101	6	molecular	molecular	JJ
cord-285778-80baxwgc	101	7	structure	structure	NN
cord-285778-80baxwgc	101	8	that	that	WDT
cord-285778-80baxwgc	101	9	is	be	VBZ
cord-285778-80baxwgc	101	10	produced	produce	VBN
cord-285778-80baxwgc	101	11	by	by	IN
cord-285778-80baxwgc	101	12	host	host	NN
cord-285778-80baxwgc	101	13	cells	cell	NNS
cord-285778-80baxwgc	101	14	when	when	WRB
cord-285778-80baxwgc	101	15	they	-PRON-	PRP
cord-285778-80baxwgc	101	16	are	be	VBP
cord-285778-80baxwgc	101	17	damaged	damage	VBN
cord-285778-80baxwgc	101	18	or	or	CC
cord-285778-80baxwgc	101	19	dying	die	VBG
cord-285778-80baxwgc	101	20	(	(	-LRB-
cord-285778-80baxwgc	101	21	with	with	IN
cord-285778-80baxwgc	101	22	or	or	CC
cord-285778-80baxwgc	101	23	without	without	IN
cord-285778-80baxwgc	101	24	pathogen	pathogen	NN
cord-285778-80baxwgc	101	25	infection	infection	NN
cord-285778-80baxwgc	101	26	)	)	-RRB-
cord-285778-80baxwgc	101	27	.	.	.
cord-285778-80baxwgc	102	1	A	a	DT
cord-285778-80baxwgc	102	2	PAMP	PAMP	NNP
cord-285778-80baxwgc	102	3	is	be	VBZ
cord-285778-80baxwgc	102	4	a	a	DT
cord-285778-80baxwgc	102	5	common	common	JJ
cord-285778-80baxwgc	102	6	molecular	molecular	JJ
cord-285778-80baxwgc	102	7	structure	structure	NN
cord-285778-80baxwgc	102	8	shared	share	VBN
cord-285778-80baxwgc	102	9	by	by	IN
cord-285778-80baxwgc	102	10	a	a	DT
cord-285778-80baxwgc	102	11	wide	wide	JJ
cord-285778-80baxwgc	102	12	variety	variety	NN
cord-285778-80baxwgc	102	13	of	of	IN
cord-285778-80baxwgc	102	14	pathogens	pathogen	NNS
cord-285778-80baxwgc	102	15	or	or	CC
cord-285778-80baxwgc	102	16	their	-PRON-	PRP$
cord-285778-80baxwgc	102	17	components	component	NNS
cord-285778-80baxwgc	102	18	or	or	CC
cord-285778-80baxwgc	102	19	products	product	NNS
cord-285778-80baxwgc	102	20	.	.	.
cord-285778-80baxwgc	103	1	In	in	IN
cord-285778-80baxwgc	103	2	the	the	DT
cord-285778-80baxwgc	103	3	case	case	NN
cord-285778-80baxwgc	103	4	of	of	IN
cord-285778-80baxwgc	103	5	pathogen	pathogen	NN
cord-285778-80baxwgc	103	6	attack	attack	NN
cord-285778-80baxwgc	103	7	,	,	,
cord-285778-80baxwgc	103	8	both	both	CC
cord-285778-80baxwgc	103	9	DAMPs	damp	NNS
cord-285778-80baxwgc	103	10	and	and	CC
cord-285778-80baxwgc	103	11	PAMPs	pamp	NNS
cord-285778-80baxwgc	103	12	will	will	MD
cord-285778-80baxwgc	103	13	be	be	VB
cord-285778-80baxwgc	103	14	present	present	JJ
cord-285778-80baxwgc	103	15	.	.	.
cord-285778-80baxwgc	104	1	Cell	cell	NN
cord-285778-80baxwgc	104	2	damage	damage	NN
cord-285778-80baxwgc	104	3	or	or	CC
cord-285778-80baxwgc	104	4	death	death	NN
cord-285778-80baxwgc	104	5	Antigens	antigen	NNS
cord-285778-80baxwgc	104	6	got	get	VBD
cord-285778-80baxwgc	104	7	their	-PRON-	PRP$
cord-285778-80baxwgc	104	8	names	name	NNS
cord-285778-80baxwgc	104	9	because	because	IN
cord-285778-80baxwgc	104	10	they	-PRON-	PRP
cord-285778-80baxwgc	104	11	were	be	VBD
cord-285778-80baxwgc	104	12	first	first	RB
cord-285778-80baxwgc	104	13	identified	identify	VBN
cord-285778-80baxwgc	104	14	as	as	IN
cord-285778-80baxwgc	104	15	pathogen	pathogen	NN
cord-285778-80baxwgc	104	16	components	component	NNS
cord-285778-80baxwgc	104	17	that	that	WDT
cord-285778-80baxwgc	104	18	could	could	MD
cord-285778-80baxwgc	104	19	bind	bind	VB
cord-285778-80baxwgc	104	20	antibodies	antibody	NNS
cord-285778-80baxwgc	104	21	;	;	,
cord-285778-80baxwgc	104	22	i.e.	i.e.	FW
cord-285778-80baxwgc	104	23	,	,	,
cord-285778-80baxwgc	104	24	they	-PRON-	PRP
cord-285778-80baxwgc	104	25	induced	induce	VBD
cord-285778-80baxwgc	104	26	"	"	``
cord-285778-80baxwgc	104	27	antibody	antibody	NN
cord-285778-80baxwgc	104	28	generation	generation	NN
cord-285778-80baxwgc	104	29	.	.	.
cord-285778-80baxwgc	104	30	"	"	''
cord-285778-80baxwgc	105	1	"	"	``
cord-285778-80baxwgc	105	2	Antigen	Antigen	NNP
cord-285778-80baxwgc	105	3	"	"	''
cord-285778-80baxwgc	105	4	now	now	RB
cord-285778-80baxwgc	105	5	refers	refer	VBZ
cord-285778-80baxwgc	105	6	to	to	IN
cord-285778-80baxwgc	105	7	structures	structure	NNS
cord-285778-80baxwgc	105	8	targeted	target	VBN
cord-285778-80baxwgc	105	9	by	by	IN
cord-285778-80baxwgc	105	10	humoral	humoral	JJ
cord-285778-80baxwgc	105	11	or	or	CC
cord-285778-80baxwgc	105	12	cell	cell	NN
cord-285778-80baxwgc	105	13	-	-	HYPH
cord-285778-80baxwgc	105	14	mediated	mediate	VBN
cord-285778-80baxwgc	105	15	responses	response	NNS
cord-285778-80baxwgc	105	16	.	.	.
cord-285778-80baxwgc	106	1	From	from	IN
cord-285778-80baxwgc	106	2	the	the	DT
cord-285778-80baxwgc	106	3	point	point	NN
cord-285778-80baxwgc	106	4	of	of	IN
cord-285778-80baxwgc	106	5	view	view	NN
cord-285778-80baxwgc	106	6	of	of	IN
cord-285778-80baxwgc	106	7	the	the	DT
cord-285778-80baxwgc	106	8	body	body	NN
cord-285778-80baxwgc	106	9	's	's	POS
cord-285778-80baxwgc	106	10	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	106	11	,	,	,
cord-285778-80baxwgc	106	12	a	a	DT
cord-285778-80baxwgc	106	13	complex	complex	JJ
cord-285778-80baxwgc	106	14	pathogen	pathogen	NN
cord-285778-80baxwgc	106	15	represents	represent	VBZ
cord-285778-80baxwgc	106	16	a	a	DT
cord-285778-80baxwgc	106	17	collection	collection	NN
cord-285778-80baxwgc	106	18	of	of	IN
cord-285778-80baxwgc	106	19	many	many	JJ
cord-285778-80baxwgc	106	20	different	different	JJ
cord-285778-80baxwgc	106	21	PAMPs	pamp	NNS
cord-285778-80baxwgc	106	22	,	,	,
cord-285778-80baxwgc	106	23	which	which	WDT
cord-285778-80baxwgc	106	24	evoke	evoke	VBP
cord-285778-80baxwgc	106	25	an	an	DT
cord-285778-80baxwgc	106	26	innate	innate	JJ
cord-285778-80baxwgc	106	27	response	response	NN
cord-285778-80baxwgc	106	28	,	,	,
cord-285778-80baxwgc	106	29	and	and	CC
cord-285778-80baxwgc	106	30	antigens	antigen	NNS
cord-285778-80baxwgc	106	31	,	,	,
cord-285778-80baxwgc	106	32	which	which	WDT
cord-285778-80baxwgc	106	33	may	may	MD
cord-285778-80baxwgc	106	34	evoke	evoke	VB
cord-285778-80baxwgc	106	35	an	an	DT
cord-285778-80baxwgc	106	36	adaptive	adaptive	JJ
cord-285778-80baxwgc	106	37	response	response	NN
cord-285778-80baxwgc	106	38	if	if	IN
cord-285778-80baxwgc	106	39	the	the	DT
cord-285778-80baxwgc	106	40	innate	innate	JJ
cord-285778-80baxwgc	106	41	response	response	NN
cord-285778-80baxwgc	106	42	is	be	VBZ
cord-285778-80baxwgc	106	43	not	not	RB
cord-285778-80baxwgc	106	44	sufficient	sufficient	JJ
cord-285778-80baxwgc	106	45	to	to	TO
cord-285778-80baxwgc	106	46	eliminate	eliminate	VB
cord-285778-80baxwgc	106	47	the	the	DT
cord-285778-80baxwgc	106	48	threat	threat	NN
cord-285778-80baxwgc	106	49	(	(	-LRB-
cord-285778-80baxwgc	106	50	Fig	Fig	NNP
cord-285778-80baxwgc	106	51	.	.	NNP
cord-285778-80baxwgc	106	52	1	1	CD
cord-285778-80baxwgc	106	53	-	-	SYM
cord-285778-80baxwgc	106	54	3	3	CD
cord-285778-80baxwgc	106	55	)	)	-RRB-
cord-285778-80baxwgc	106	56	.	.	.
cord-285778-80baxwgc	107	1	Anatomically	anatomically	RB
cord-285778-80baxwgc	107	2	,	,	,
cord-285778-80baxwgc	107	3	an	an	DT
cord-285778-80baxwgc	107	4	innate	innate	JJ
cord-285778-80baxwgc	107	5	response	response	NN
cord-285778-80baxwgc	107	6	can	can	MD
cord-285778-80baxwgc	107	7	be	be	VB
cord-285778-80baxwgc	107	8	triggered	trigger	VBN
cord-285778-80baxwgc	107	9	at	at	IN
cord-285778-80baxwgc	107	10	any	any	DT
cord-285778-80baxwgc	107	11	point	point	NN
cord-285778-80baxwgc	107	12	in	in	IN
cord-285778-80baxwgc	107	13	the	the	DT
cord-285778-80baxwgc	107	14	body	body	NN
cord-285778-80baxwgc	107	15	because	because	IN
cord-285778-80baxwgc	107	16	the	the	DT
cord-285778-80baxwgc	107	17	majority	majority	NN
cord-285778-80baxwgc	107	18	of	of	IN
cord-285778-80baxwgc	107	19	innate	innate	JJ
cord-285778-80baxwgc	107	20	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	107	21	are	be	VBP
cord-285778-80baxwgc	107	22	positioned	position	VBN
cord-285778-80baxwgc	107	23	where	where	WRB
cord-285778-80baxwgc	107	24	microbes	microbe	NNS
cord-285778-80baxwgc	107	25	most	most	RBS
cord-285778-80baxwgc	107	26	commonly	commonly	RB
cord-285778-80baxwgc	107	27	attempt	attempt	VBP
cord-285778-80baxwgc	107	28	to	to	TO
cord-285778-80baxwgc	107	29	gain	gain	VB
cord-285778-80baxwgc	107	30	access	access	NN
cord-285778-80baxwgc	107	31	:	:	:
cord-285778-80baxwgc	107	32	just	just	RB
cord-285778-80baxwgc	107	33	below	below	IN
cord-285778-80baxwgc	107	34	the	the	DT
cord-285778-80baxwgc	107	35	skin	skin	NN
cord-285778-80baxwgc	107	36	surface	surface	NN
cord-285778-80baxwgc	107	37	or	or	CC
cord-285778-80baxwgc	107	38	at	at	IN
cord-285778-80baxwgc	107	39	the	the	DT
cord-285778-80baxwgc	107	40	mucosae	mucosae	JJ
cord-285778-80baxwgc	107	41	protecting	protect	VBG
cord-285778-80baxwgc	107	42	body	body	NN
cord-285778-80baxwgc	107	43	tracts	tract	NNS
cord-285778-80baxwgc	107	44	such	such	JJ
cord-285778-80baxwgc	107	45	as	as	IN
cord-285778-80baxwgc	107	46	the	the	DT
cord-285778-80baxwgc	107	47	gut	gut	NN
cord-285778-80baxwgc	107	48	and	and	CC
cord-285778-80baxwgc	107	49	respiratory	respiratory	JJ
cord-285778-80baxwgc	107	50	system	system	NN
cord-285778-80baxwgc	107	51	.	.	.
cord-285778-80baxwgc	108	1	Most	Most	JJS
cord-285778-80baxwgc	108	2	of	of	IN
cord-285778-80baxwgc	108	3	the	the	DT
cord-285778-80baxwgc	108	4	time	time	NN
cord-285778-80baxwgc	108	5	,	,	,
cord-285778-80baxwgc	108	6	the	the	DT
cord-285778-80baxwgc	108	7	innate	innate	JJ
cord-285778-80baxwgc	108	8	response	response	NN
cord-285778-80baxwgc	108	9	successfully	successfully	RB
cord-285778-80baxwgc	108	10	eliminates	eliminate	VBZ
cord-285778-80baxwgc	108	11	an	an	DT
cord-285778-80baxwgc	108	12	invader	invader	NN
cord-285778-80baxwgc	108	13	.	.	.
cord-285778-80baxwgc	109	1	Only	only	RB
cord-285778-80baxwgc	109	2	those	those	DT
cord-285778-80baxwgc	109	3	entities	entity	NNS
cord-285778-80baxwgc	109	4	that	that	WDT
cord-285778-80baxwgc	109	5	succeed	succeed	VBP
cord-285778-80baxwgc	109	6	in	in	IN
cord-285778-80baxwgc	109	7	overwhelming	overwhelm	VBG
cord-285778-80baxwgc	109	8	the	the	DT
cord-285778-80baxwgc	109	9	innate	innate	JJ
cord-285778-80baxwgc	109	10	defenses	defense	NNS
cord-285778-80baxwgc	109	11	trigger	trigger	VBP
cord-285778-80baxwgc	109	12	adaptive	adaptive	JJ
cord-285778-80baxwgc	109	13	responses	response	NNS
cord-285778-80baxwgc	109	14	that	that	WDT
cord-285778-80baxwgc	109	15	are	be	VBP
cord-285778-80baxwgc	109	16	initiated	initiate	VBN
cord-285778-80baxwgc	109	17	by	by	IN
cord-285778-80baxwgc	109	18	adaptive	adaptive	JJ
cord-285778-80baxwgc	109	19	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	109	20	positioned	position	VBN
cord-285778-80baxwgc	109	21	in	in	IN
cord-285778-80baxwgc	109	22	specialized	specialized	JJ
cord-285778-80baxwgc	109	23	anatomical	anatomical	JJ
cord-285778-80baxwgc	109	24	regions	region	NNS
cord-285778-80baxwgc	109	25	called	call	VBD
cord-285778-80baxwgc	109	26	the	the	DT
cord-285778-80baxwgc	109	27	lymphoid	lymphoid	JJ
cord-285778-80baxwgc	109	28	tissues	tissue	NNS
cord-285778-80baxwgc	109	29	,	,	,
cord-285778-80baxwgc	109	30	which	which	WDT
cord-285778-80baxwgc	109	31	include	include	VBP
cord-285778-80baxwgc	109	32	the	the	DT
cord-285778-80baxwgc	109	33	spleen	spleen	NNS
cord-285778-80baxwgc	109	34	,	,	,
cord-285778-80baxwgc	109	35	tonsils	tonsil	NNS
cord-285778-80baxwgc	109	36	and	and	CC
cord-285778-80baxwgc	109	37	lymph	lymph	NN
cord-285778-80baxwgc	109	38	nodes	node	NNS
cord-285778-80baxwgc	109	39	(	(	-LRB-
cord-285778-80baxwgc	109	40	see	see	VB
cord-285778-80baxwgc	109	41	Ch	Ch	NNP
cord-285778-80baxwgc	109	42	.	.	NNP
cord-285778-80baxwgc	109	43	2	2	CD
cord-285778-80baxwgc	109	44	)	)	-RRB-
cord-285778-80baxwgc	109	45	.	.	.
cord-285778-80baxwgc	110	1	The	the	DT
cord-285778-80baxwgc	110	2	general	general	JJ
cord-285778-80baxwgc	110	3	characteristics	characteristic	NNS
cord-285778-80baxwgc	110	4	of	of	IN
cord-285778-80baxwgc	110	5	innate	innate	JJ
cord-285778-80baxwgc	110	6	and	and	CC
cord-285778-80baxwgc	110	7	adaptive	adaptive	JJ
cord-285778-80baxwgc	110	8	immune	immune	JJ
cord-285778-80baxwgc	110	9	responses	response	NNS
cord-285778-80baxwgc	111	1	primarily	primarily	RB
cord-285778-80baxwgc	111	2	as	as	IN
cord-285778-80baxwgc	111	3	they	-PRON-	PRP
cord-285778-80baxwgc	111	4	relate	relate	VBP
cord-285778-80baxwgc	111	5	to	to	IN
cord-285778-80baxwgc	111	6	pathogens	pathogen	NNS
cord-285778-80baxwgc	111	7	are	be	VBP
cord-285778-80baxwgc	111	8	described	describe	VBN
cord-285778-80baxwgc	111	9	in	in	IN
cord-285778-80baxwgc	111	10	more	more	JJR
cord-285778-80baxwgc	111	11	detail	detail	NN
cord-285778-80baxwgc	111	12	in	in	IN
cord-285778-80baxwgc	111	13	the	the	DT
cord-285778-80baxwgc	111	14	next	next	JJ
cord-285778-80baxwgc	111	15	two	two	CD
cord-285778-80baxwgc	111	16	sections	section	NNS
cord-285778-80baxwgc	111	17	.	.	.
cord-285778-80baxwgc	112	1	In	in	IN
cord-285778-80baxwgc	112	2	this	this	DT
cord-285778-80baxwgc	112	3	section	section	NN
cord-285778-80baxwgc	112	4	,	,	,
cord-285778-80baxwgc	112	5	we	-PRON-	PRP
cord-285778-80baxwgc	112	6	present	present	VBP
cord-285778-80baxwgc	112	7	a	a	DT
cord-285778-80baxwgc	112	8	general	general	JJ
cord-285778-80baxwgc	112	9	introduction	introduction	NN
cord-285778-80baxwgc	112	10	to	to	IN
cord-285778-80baxwgc	112	11	the	the	DT
cord-285778-80baxwgc	112	12	central	central	JJ
cord-285778-80baxwgc	112	13	elements	element	NNS
cord-285778-80baxwgc	112	14	of	of	IN
cord-285778-80baxwgc	112	15	innate	innate	JJ
cord-285778-80baxwgc	112	16	immunity	immunity	NN
cord-285778-80baxwgc	112	17	,	,	,
cord-285778-80baxwgc	112	18	namely	namely	RB
cord-285778-80baxwgc	112	19	barrier	barrier	NN
cord-285778-80baxwgc	112	20	defenses	defense	NNS
cord-285778-80baxwgc	112	21	,	,	,
cord-285778-80baxwgc	112	22	complement	complement	NN
cord-285778-80baxwgc	112	23	activation	activation	NN
cord-285778-80baxwgc	112	24	,	,	,
cord-285778-80baxwgc	112	25	pattern	pattern	NN
cord-285778-80baxwgc	112	26	recognition	recognition	NN
cord-285778-80baxwgc	112	27	,	,	,
cord-285778-80baxwgc	112	28	inflammation	inflammation	NN
cord-285778-80baxwgc	112	29	,	,	,
cord-285778-80baxwgc	112	30	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	112	31	and	and	CC
cord-285778-80baxwgc	112	32	target	target	NN
cord-285778-80baxwgc	112	33	cell	cell	NN
cord-285778-80baxwgc	112	34	lysis	lysis	NN
cord-285778-80baxwgc	112	35	.	.	.
cord-285778-80baxwgc	113	1	More	more	RBR
cord-285778-80baxwgc	113	2	detailed	detailed	JJ
cord-285778-80baxwgc	113	3	information	information	NN
cord-285778-80baxwgc	113	4	about	about	IN
cord-285778-80baxwgc	113	5	the	the	DT
cord-285778-80baxwgc	113	6	innate	innate	JJ
cord-285778-80baxwgc	113	7	immune	immune	JJ
cord-285778-80baxwgc	113	8	response	response	NN
cord-285778-80baxwgc	113	9	can	can	MD
cord-285778-80baxwgc	113	10	be	be	VB
cord-285778-80baxwgc	113	11	found	find	VBN
cord-285778-80baxwgc	113	12	in	in	IN
cord-285778-80baxwgc	113	13	Chapter	chapter	NN
cord-285778-80baxwgc	113	14	3	3	CD
cord-285778-80baxwgc	113	15	on	on	IN
cord-285778-80baxwgc	113	16	innate	innate	JJ
cord-285778-80baxwgc	113	17	immunity	immunity	NN
cord-285778-80baxwgc	113	18	.	.	.
cord-285778-80baxwgc	113	19	 	 	_SP
cord-285778-80baxwgc	114	1	Innate	innate	JJ
cord-285778-80baxwgc	114	2	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	114	3	express	express	VBP
cord-285778-80baxwgc	114	4	a	a	DT
cord-285778-80baxwgc	114	5	small	small	JJ
cord-285778-80baxwgc	114	6	number	number	NN
cord-285778-80baxwgc	114	7	of	of	IN
cord-285778-80baxwgc	114	8	pattern	pattern	NN
cord-285778-80baxwgc	114	9	recognition	recognition	NN
cord-285778-80baxwgc	114	10	molecules	molecule	NNS
cord-285778-80baxwgc	114	11	(	(	-LRB-
cord-285778-80baxwgc	114	12	PRMs	PRMs	NNP
cord-285778-80baxwgc	114	13	)	)	-RRB-
cord-285778-80baxwgc	114	14	of	of	IN
cord-285778-80baxwgc	114	15	limited	limited	JJ
cord-285778-80baxwgc	114	16	diversity	diversity	NN
cord-285778-80baxwgc	114	17	that	that	WDT
cord-285778-80baxwgc	114	18	collectively	collectively	RB
cord-285778-80baxwgc	114	19	recognize	recognize	VBP
cord-285778-80baxwgc	114	20	a	a	DT
cord-285778-80baxwgc	114	21	wide	wide	JJ
cord-285778-80baxwgc	114	22	range	range	NN
cord-285778-80baxwgc	114	23	of	of	IN
cord-285778-80baxwgc	114	24	threats	threat	NNS
cord-285778-80baxwgc	114	25	Adaptive	adaptive	JJ
cord-285778-80baxwgc	114	26	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	114	27	express	express	VBP
cord-285778-80baxwgc	114	28	an	an	DT
cord-285778-80baxwgc	114	29	almost	almost	RB
cord-285778-80baxwgc	114	30	infinite	infinite	JJ
cord-285778-80baxwgc	114	31	number	number	NN
cord-285778-80baxwgc	114	32	of	of	IN
cord-285778-80baxwgc	114	33	extremely	extremely	RB
cord-285778-80baxwgc	114	34	diverse	diverse	JJ
cord-285778-80baxwgc	114	35	antigen	antigen	NN
cord-285778-80baxwgc	114	36	receptors	receptor	NNS
cord-285778-80baxwgc	114	37	,	,	,
cord-285778-80baxwgc	114	38	each	each	DT
cord-285778-80baxwgc	114	39	of	of	IN
cord-285778-80baxwgc	114	40	which	which	WDT
cord-285778-80baxwgc	114	41	is	be	VBZ
cord-285778-80baxwgc	114	42	specific	specific	JJ
cord-285778-80baxwgc	114	43	for	for	IN
cord-285778-80baxwgc	114	44	a	a	DT
cord-285778-80baxwgc	114	45	particular	particular	JJ
cord-285778-80baxwgc	114	46	pathogen	pathogen	NN
cord-285778-80baxwgc	114	47	Response	response	NN
cord-285778-80baxwgc	114	48	is	be	VBZ
cord-285778-80baxwgc	114	49	triggered	trigger	VBN
cord-285778-80baxwgc	114	50	by	by	IN
cord-285778-80baxwgc	114	51	PRM	PRM	NNP
cord-285778-80baxwgc	114	52	binding	bind	VBG
cord-285778-80baxwgc	114	53	to	to	IN
cord-285778-80baxwgc	114	54	widely	widely	RB
cord-285778-80baxwgc	114	55	shared	share	VBN
cord-285778-80baxwgc	114	56	damageassociated	damageassociate	VBN
cord-285778-80baxwgc	114	57	molecular	molecular	JJ
cord-285778-80baxwgc	114	58	patterns	pattern	NNS
cord-285778-80baxwgc	114	59	(	(	-LRB-
cord-285778-80baxwgc	114	60	DAMPs	damp	NNS
cord-285778-80baxwgc	114	61	)	)	-RRB-
cord-285778-80baxwgc	114	62	or	or	CC
cord-285778-80baxwgc	114	63	pathogen	pathogen	NN
cord-285778-80baxwgc	114	64	-	-	HYPH
cord-285778-80baxwgc	114	65	associated	associate	VBN
cord-285778-80baxwgc	114	66	molecular	molecular	JJ
cord-285778-80baxwgc	114	67	patterns	pattern	NNS
cord-285778-80baxwgc	115	1	(	(	-LRB-
cord-285778-80baxwgc	115	2	PAMPs	pamp	NNS
cord-285778-80baxwgc	115	3	)	)	-RRB-
cord-285778-80baxwgc	115	4	Response	response	NN
cord-285778-80baxwgc	115	5	is	be	VBZ
cord-285778-80baxwgc	115	6	triggered	trigger	VBN
cord-285778-80baxwgc	115	7	by	by	IN
cord-285778-80baxwgc	115	8	antigen	antigen	NN
cord-285778-80baxwgc	115	9	receptor	receptor	NN
cord-285778-80baxwgc	115	10	binding	bind	VBG
cord-285778-80baxwgc	115	11	to	to	IN
cord-285778-80baxwgc	115	12	a	a	DT
cord-285778-80baxwgc	115	13	unique	unique	JJ
cord-285778-80baxwgc	115	14	antigen	antigen	NN
cord-285778-80baxwgc	115	15	derived	derive	VBN
cord-285778-80baxwgc	115	16	from	from	IN
cord-285778-80baxwgc	115	17	a	a	DT
cord-285778-80baxwgc	115	18	specific	specific	JJ
cord-285778-80baxwgc	115	19	pathogen	pathogen	NN
cord-285778-80baxwgc	115	20	Number	number	NN
cord-285778-80baxwgc	115	21	of	of	IN
cord-285778-80baxwgc	115	22	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	115	23	responding	respond	VBG
cord-285778-80baxwgc	115	24	to	to	IN
cord-285778-80baxwgc	115	25	a	a	DT
cord-285778-80baxwgc	115	26	given	give	VBN
cord-285778-80baxwgc	115	27	threat	threat	NN
cord-285778-80baxwgc	115	28	is	be	VBZ
cord-285778-80baxwgc	115	29	large	large	JJ
cord-285778-80baxwgc	115	30	,	,	,
cord-285778-80baxwgc	115	31	so	so	CC
cord-285778-80baxwgc	115	32	no	no	DT
cord-285778-80baxwgc	115	33	proliferation	proliferation	NN
cord-285778-80baxwgc	115	34	is	be	VBZ
cord-285778-80baxwgc	115	35	required	require	VBN
cord-285778-80baxwgc	115	36	and	and	CC
cord-285778-80baxwgc	115	37	response	response	NN
cord-285778-80baxwgc	115	38	is	be	VBZ
cord-285778-80baxwgc	115	39	fast	fast	JJ
cord-285778-80baxwgc	115	40	Number	number	NN
cord-285778-80baxwgc	115	41	of	of	IN
cord-285778-80baxwgc	115	42	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	115	43	responding	respond	VBG
cord-285778-80baxwgc	115	44	to	to	IN
cord-285778-80baxwgc	115	45	a	a	DT
cord-285778-80baxwgc	115	46	given	give	VBN
cord-285778-80baxwgc	115	47	threat	threat	NN
cord-285778-80baxwgc	115	48	is	be	VBZ
cord-285778-80baxwgc	115	49	very	very	RB
cord-285778-80baxwgc	115	50	small	small	JJ
cord-285778-80baxwgc	115	51	,	,	,
cord-285778-80baxwgc	115	52	so	so	IN
cord-285778-80baxwgc	115	53	proliferation	proliferation	NN
cord-285778-80baxwgc	115	54	is	be	VBZ
cord-285778-80baxwgc	115	55	required	require	VBN
cord-285778-80baxwgc	115	56	and	and	CC
cord-285778-80baxwgc	115	57	response	response	NN
cord-285778-80baxwgc	115	58	is	be	VBZ
cord-285778-80baxwgc	115	59	slower	slow	JJR
cord-285778-80baxwgc	115	60	Responding	respond	VBG
cord-285778-80baxwgc	115	61	cells	cell	NNS
cord-285778-80baxwgc	115	62	do	do	VBP
cord-285778-80baxwgc	115	63	not	not	RB
cord-285778-80baxwgc	115	64	proliferate	proliferate	VB
cord-285778-80baxwgc	115	65	and	and	CC
cord-285778-80baxwgc	115	66	are	be	VBP
cord-285778-80baxwgc	115	67	short	short	RB
cord-285778-80baxwgc	115	68	-	-	HYPH
cord-285778-80baxwgc	115	69	lived	lived	JJ
cord-285778-80baxwgc	115	70	,	,	,
cord-285778-80baxwgc	115	71	so	so	RB
cord-285778-80baxwgc	115	72	level	level	NN
cord-285778-80baxwgc	115	73	of	of	IN
cord-285778-80baxwgc	115	74	defense	defense	NN
cord-285778-80baxwgc	115	75	is	be	VBZ
cord-285778-80baxwgc	115	76	similar	similar	JJ
cord-285778-80baxwgc	115	77	upon	upon	IN
cord-285778-80baxwgc	115	78	repeated	repeat	VBN
cord-285778-80baxwgc	115	79	exposure	exposure	NN
cord-285778-80baxwgc	115	80	to	to	IN
cord-285778-80baxwgc	115	81	the	the	DT
cord-285778-80baxwgc	115	82	same	same	JJ
cord-285778-80baxwgc	115	83	pathogen	pathogen	NN
cord-285778-80baxwgc	115	84	Responding	respond	VBG
cord-285778-80baxwgc	115	85	cells	cell	NNS
cord-285778-80baxwgc	115	86	proliferate	proliferate	VBP
cord-285778-80baxwgc	115	87	and	and	CC
cord-285778-80baxwgc	115	88	are	be	VBP
cord-285778-80baxwgc	115	89	long	long	RB
cord-285778-80baxwgc	115	90	-	-	HYPH
cord-285778-80baxwgc	115	91	lived	live	VBN
cord-285778-80baxwgc	115	92	,	,	,
cord-285778-80baxwgc	115	93	so	so	RB
cord-285778-80baxwgc	115	94	level	level	NN
cord-285778-80baxwgc	115	95	of	of	IN
cord-285778-80baxwgc	115	96	defense	defense	NN
cord-285778-80baxwgc	115	97	is	be	VBZ
cord-285778-80baxwgc	115	98	stronger	strong	JJR
cord-285778-80baxwgc	115	99	and	and	CC
cord-285778-80baxwgc	115	100	faster	fast	RBR
cord-285778-80baxwgc	115	101	with	with	IN
cord-285778-80baxwgc	115	102	repeated	repeat	VBN
cord-285778-80baxwgc	115	103	exposure	exposure	NN
cord-285778-80baxwgc	115	104	to	to	IN
cord-285778-80baxwgc	115	105	the	the	DT
cord-285778-80baxwgc	115	106	same	same	JJ
cord-285778-80baxwgc	115	107	pathogen	pathogen	NN
cord-285778-80baxwgc	115	108	A	a	NN
cord-285778-80baxwgc	116	1	given	give	VBN
cord-285778-80baxwgc	116	2	PAMP	PAMP	NNP
cord-285778-80baxwgc	116	3	is	be	VBZ
cord-285778-80baxwgc	116	4	expressed	express	VBN
cord-285778-80baxwgc	116	5	by	by	IN
cord-285778-80baxwgc	116	6	a	a	DT
cord-285778-80baxwgc	116	7	wide	wide	JJ
cord-285778-80baxwgc	116	8	variety	variety	NN
cord-285778-80baxwgc	116	9	of	of	IN
cord-285778-80baxwgc	116	10	pathogens	pathogen	NNS
cord-285778-80baxwgc	116	11	and	and	CC
cord-285778-80baxwgc	116	12	is	be	VBZ
cord-285778-80baxwgc	116	13	recognized	recognize	VBN
cord-285778-80baxwgc	116	14	by	by	IN
cord-285778-80baxwgc	116	15	PRMs	prm	NNS
cord-285778-80baxwgc	116	16	whose	whose	WP$
cord-285778-80baxwgc	116	17	engagement	engagement	NN
cord-285778-80baxwgc	116	18	activates	activate	VBZ
cord-285778-80baxwgc	116	19	innate	innate	JJ
cord-285778-80baxwgc	116	20	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	116	21	.	.	.
cord-285778-80baxwgc	117	1	An	an	DT
cord-285778-80baxwgc	117	2	antigen	antigen	NN
cord-285778-80baxwgc	117	3	is	be	VBZ
cord-285778-80baxwgc	117	4	a	a	DT
cord-285778-80baxwgc	117	5	molecular	molecular	JJ
cord-285778-80baxwgc	117	6	structure	structure	NN
cord-285778-80baxwgc	117	7	that	that	WDT
cord-285778-80baxwgc	117	8	is	be	VBZ
cord-285778-80baxwgc	117	9	generally	generally	RB
cord-285778-80baxwgc	117	10	unique	unique	JJ
cord-285778-80baxwgc	117	11	to	to	IN
cord-285778-80baxwgc	117	12	a	a	DT
cord-285778-80baxwgc	117	13	specific	specific	JJ
cord-285778-80baxwgc	117	14	pathogen	pathogen	NN
cord-285778-80baxwgc	117	15	and	and	CC
cord-285778-80baxwgc	117	16	is	be	VBZ
cord-285778-80baxwgc	117	17	recognized	recognize	VBN
cord-285778-80baxwgc	117	18	by	by	IN
cord-285778-80baxwgc	117	19	a	a	DT
cord-285778-80baxwgc	117	20	specific	specific	JJ
cord-285778-80baxwgc	117	21	antigen	antigen	NN
cord-285778-80baxwgc	117	22	receptor	receptor	NN
cord-285778-80baxwgc	117	23	whose	whose	WP$
cord-285778-80baxwgc	117	24	engagement	engagement	NN
cord-285778-80baxwgc	117	25	activates	activate	VBZ
cord-285778-80baxwgc	117	26	a	a	DT
cord-285778-80baxwgc	117	27	particular	particular	JJ
cord-285778-80baxwgc	117	28	adaptive	adaptive	JJ
cord-285778-80baxwgc	117	29	leukocyte	leukocyte	NN
cord-285778-80baxwgc	117	30	.	.	.
cord-285778-80baxwgc	118	1	Pathogen	pathogen	NN
cord-285778-80baxwgc	118	2	2	2	CD
cord-285778-80baxwgc	118	3	Antigens	Antigens	NNP
cord-285778-80baxwgc	118	4	PAMPs	pamp	NNS
cord-285778-80baxwgc	118	5	NOTE	note	NN
cord-285778-80baxwgc	118	6	:	:	:
cord-285778-80baxwgc	119	1	Elements	element	NNS
cord-285778-80baxwgc	119	2	of	of	IN
cord-285778-80baxwgc	119	3	an	an	DT
cord-285778-80baxwgc	119	4	innate	innate	JJ
cord-285778-80baxwgc	119	5	immune	immune	JJ
cord-285778-80baxwgc	119	6	response	response	NN
cord-285778-80baxwgc	119	7	can	can	MD
cord-285778-80baxwgc	119	8	be	be	VB
cord-285778-80baxwgc	119	9	found	find	VBN
cord-285778-80baxwgc	119	10	in	in	IN
cord-285778-80baxwgc	119	11	all	all	DT
cord-285778-80baxwgc	119	12	multicellular	multicellular	JJ
cord-285778-80baxwgc	119	13	organisms	organism	NNS
cord-285778-80baxwgc	119	14	,	,	,
cord-285778-80baxwgc	119	15	whereas	whereas	IN
cord-285778-80baxwgc	119	16	the	the	DT
cord-285778-80baxwgc	119	17	mechanisms	mechanism	NNS
cord-285778-80baxwgc	119	18	of	of	IN
cord-285778-80baxwgc	119	19	the	the	DT
cord-285778-80baxwgc	119	20	more	more	RBR
cord-285778-80baxwgc	119	21	recently	recently	RB
cord-285778-80baxwgc	119	22	evolved	evolve	VBN
cord-285778-80baxwgc	119	23	adaptive	adaptive	JJ
cord-285778-80baxwgc	119	24	immune	immune	JJ
cord-285778-80baxwgc	119	25	response	response	NN
cord-285778-80baxwgc	119	26	are	be	VBP
cord-285778-80baxwgc	119	27	present	present	JJ
cord-285778-80baxwgc	119	28	only	only	RB
cord-285778-80baxwgc	119	29	in	in	IN
cord-285778-80baxwgc	119	30	the	the	DT
cord-285778-80baxwgc	119	31	higher	high	JJR
cord-285778-80baxwgc	119	32	vertebrates	vertebrate	NNS
cord-285778-80baxwgc	119	33	(	(	-LRB-
cord-285778-80baxwgc	119	34	fish	fish	NN
cord-285778-80baxwgc	119	35	and	and	CC
cord-285778-80baxwgc	119	36	above	above	RB
cord-285778-80baxwgc	119	37	)	)	-RRB-
cord-285778-80baxwgc	119	38	.	.	.
cord-285778-80baxwgc	120	1	Appendix	Appendix	NNP
cord-285778-80baxwgc	120	2	C	C	NNP
cord-285778-80baxwgc	120	3	contains	contain	VBZ
cord-285778-80baxwgc	120	4	a	a	DT
cord-285778-80baxwgc	120	5	Table	Table	NNP
cord-285778-80baxwgc	120	6	of	of	IN
cord-285778-80baxwgc	120	7	Comparative	Comparative	NNP
cord-285778-80baxwgc	120	8	Immunology	Immunology	NNP
cord-285778-80baxwgc	120	9	that	that	WDT
cord-285778-80baxwgc	120	10	summarizes	summarize	VBZ
cord-285778-80baxwgc	120	11	the	the	DT
cord-285778-80baxwgc	120	12	immune	immune	JJ
cord-285778-80baxwgc	120	13	system	system	NN
cord-285778-80baxwgc	120	14	elements	element	NNS
cord-285778-80baxwgc	120	15	present	present	JJ
cord-285778-80baxwgc	120	16	in	in	IN
cord-285778-80baxwgc	120	17	an	an	DT
cord-285778-80baxwgc	120	18	evolutionarily	evolutionarily	RB
cord-285778-80baxwgc	120	19	diverse	diverse	JJ
cord-285778-80baxwgc	120	20	range	range	NN
cord-285778-80baxwgc	120	21	of	of	IN
cord-285778-80baxwgc	120	22	animals	animal	NNS
cord-285778-80baxwgc	120	23	.	.	.
cord-285778-80baxwgc	121	1	The	the	DT
cord-285778-80baxwgc	121	2	first	first	JJ
cord-285778-80baxwgc	121	3	level	level	NN
cord-285778-80baxwgc	121	4	of	of	IN
cord-285778-80baxwgc	121	5	innate	innate	JJ
cord-285778-80baxwgc	121	6	defense	defense	NN
cord-285778-80baxwgc	121	7	is	be	VBZ
cord-285778-80baxwgc	121	8	mediated	mediate	VBN
cord-285778-80baxwgc	121	9	by	by	IN
cord-285778-80baxwgc	121	10	a	a	DT
cord-285778-80baxwgc	121	11	pre	pre	JJ
cord-285778-80baxwgc	121	12	-	-	JJ
cord-285778-80baxwgc	121	13	existing	existing	JJ
cord-285778-80baxwgc	121	14	collection	collection	NN
cord-285778-80baxwgc	121	15	of	of	IN
cord-285778-80baxwgc	121	16	physical	physical	JJ
cord-285778-80baxwgc	121	17	,	,	,
cord-285778-80baxwgc	121	18	chemical	chemical	NN
cord-285778-80baxwgc	121	19	and	and	CC
cord-285778-80baxwgc	121	20	molecular	molecular	JJ
cord-285778-80baxwgc	121	21	barriers	barrier	NNS
cord-285778-80baxwgc	121	22	that	that	WDT
cord-285778-80baxwgc	121	23	exclude	exclude	VBP
cord-285778-80baxwgc	121	24	foreign	foreign	JJ
cord-285778-80baxwgc	121	25	material	material	NN
cord-285778-80baxwgc	121	26	in	in	IN
cord-285778-80baxwgc	121	27	a	a	DT
cord-285778-80baxwgc	121	28	way	way	NN
cord-285778-80baxwgc	121	29	that	that	WDT
cord-285778-80baxwgc	121	30	is	be	VBZ
cord-285778-80baxwgc	121	31	totally	totally	RB
cord-285778-80baxwgc	121	32	non	non	JJ
cord-285778-80baxwgc	121	33	-	-	JJ
cord-285778-80baxwgc	121	34	specific	specific	JJ
cord-285778-80baxwgc	121	35	and	and	CC
cord-285778-80baxwgc	121	36	requires	require	VBZ
cord-285778-80baxwgc	121	37	no	no	DT
cord-285778-80baxwgc	121	38	induction	induction	NN
cord-285778-80baxwgc	121	39	.	.	.
cord-285778-80baxwgc	122	1	These	these	DT
cord-285778-80baxwgc	122	2	elements	element	NNS
cord-285778-80baxwgc	122	3	include	include	VBP
cord-285778-80baxwgc	122	4	anatomical	anatomical	JJ
cord-285778-80baxwgc	122	5	barriers	barrier	NNS
cord-285778-80baxwgc	122	6	and	and	CC
cord-285778-80baxwgc	122	7	physiological	physiological	JJ
cord-285778-80baxwgc	122	8	barriers	barrier	NNS
cord-285778-80baxwgc	122	9	.	.	.
cord-285778-80baxwgc	123	1	An	an	DT
cord-285778-80baxwgc	123	2	example	example	NN
cord-285778-80baxwgc	123	3	of	of	IN
cord-285778-80baxwgc	123	4	an	an	DT
cord-285778-80baxwgc	123	5	anatomical	anatomical	JJ
cord-285778-80baxwgc	123	6	barrier	barrier	NN
cord-285778-80baxwgc	123	7	is	be	VBZ
cord-285778-80baxwgc	123	8	intact	intact	JJ
cord-285778-80baxwgc	123	9	skin	skin	NN
cord-285778-80baxwgc	123	10	,	,	,
cord-285778-80baxwgc	123	11	while	while	IN
cord-285778-80baxwgc	123	12	the	the	DT
cord-285778-80baxwgc	123	13	low	low	JJ
cord-285778-80baxwgc	123	14	pH	ph	NN
cord-285778-80baxwgc	123	15	of	of	IN
cord-285778-80baxwgc	123	16	stomach	stomach	NN
cord-285778-80baxwgc	123	17	acid	acid	NN
cord-285778-80baxwgc	123	18	and	and	CC
cord-285778-80baxwgc	123	19	the	the	DT
cord-285778-80baxwgc	123	20	hydrolytic	hydrolytic	JJ
cord-285778-80baxwgc	123	21	enzymes	enzyme	NNS
cord-285778-80baxwgc	123	22	in	in	IN
cord-285778-80baxwgc	123	23	body	body	NN
cord-285778-80baxwgc	123	24	secretions	secretion	NNS
cord-285778-80baxwgc	123	25	are	be	VBP
cord-285778-80baxwgc	123	26	examples	example	NNS
cord-285778-80baxwgc	123	27	of	of	IN
cord-285778-80baxwgc	123	28	physiological	physiological	JJ
cord-285778-80baxwgc	123	29	barriers	barrier	NNS
cord-285778-80baxwgc	123	30	.	.	.
cord-285778-80baxwgc	124	1	Should	Should	MD
cord-285778-80baxwgc	124	2	barrier	barrier	VB
cord-285778-80baxwgc	124	3	defense	defense	NN
cord-285778-80baxwgc	124	4	prove	prove	VB
cord-285778-80baxwgc	124	5	insufficient	insufficient	JJ
cord-285778-80baxwgc	124	6	,	,	,
cord-285778-80baxwgc	124	7	other	other	JJ
cord-285778-80baxwgc	124	8	forms	form	NNS
cord-285778-80baxwgc	124	9	of	of	IN
cord-285778-80baxwgc	124	10	innate	innate	JJ
cord-285778-80baxwgc	124	11	defense	defense	NN
cord-285778-80baxwgc	124	12	are	be	VBP
cord-285778-80baxwgc	124	13	induced	induce	VBN
cord-285778-80baxwgc	124	14	.	.	.
cord-285778-80baxwgc	125	1	A	a	DT
cord-285778-80baxwgc	125	2	key	key	JJ
cord-285778-80baxwgc	125	3	player	player	NN
cord-285778-80baxwgc	125	4	in	in	IN
cord-285778-80baxwgc	125	5	the	the	DT
cord-285778-80baxwgc	125	6	induced	induce	VBN
cord-285778-80baxwgc	125	7	innate	innate	JJ
cord-285778-80baxwgc	125	8	response	response	NN
cord-285778-80baxwgc	125	9	is	be	VBZ
cord-285778-80baxwgc	125	10	complement	complement	JJ
cord-285778-80baxwgc	125	11	,	,	,
cord-285778-80baxwgc	125	12	a	a	DT
cord-285778-80baxwgc	125	13	complex	complex	JJ
cord-285778-80baxwgc	125	14	system	system	NN
cord-285778-80baxwgc	125	15	of	of	IN
cord-285778-80baxwgc	125	16	enzymes	enzyme	NNS
cord-285778-80baxwgc	125	17	that	that	WDT
cord-285778-80baxwgc	125	18	circulates	circulate	VBZ
cord-285778-80baxwgc	125	19	in	in	IN
cord-285778-80baxwgc	125	20	the	the	DT
cord-285778-80baxwgc	125	21	blood	blood	NN
cord-285778-80baxwgc	125	22	in	in	IN
cord-285778-80baxwgc	125	23	an	an	DT
cord-285778-80baxwgc	125	24	inactive	inactive	JJ
cord-285778-80baxwgc	125	25	state	state	NN
cord-285778-80baxwgc	125	26	.	.	.
cord-285778-80baxwgc	126	1	Once	once	RB
cord-285778-80baxwgc	126	2	activated	activate	VBN
cord-285778-80baxwgc	126	3	,	,	,
cord-285778-80baxwgc	126	4	the	the	DT
cord-285778-80baxwgc	126	5	complement	complement	NN
cord-285778-80baxwgc	126	6	system	system	NN
cord-285778-80baxwgc	126	7	contributes	contribute	VBZ
cord-285778-80baxwgc	126	8	directly	directly	RB
cord-285778-80baxwgc	126	9	and	and	CC
cord-285778-80baxwgc	126	10	indirectly	indirectly	RB
cord-285778-80baxwgc	126	11	to	to	TO
cord-285778-80baxwgc	126	12	innate	innate	VB
cord-285778-80baxwgc	126	13	and	and	CC
cord-285778-80baxwgc	126	14	adaptive	adaptive	JJ
cord-285778-80baxwgc	126	15	immune	immune	JJ
cord-285778-80baxwgc	126	16	defenses	defense	NNS
cord-285778-80baxwgc	126	17	,	,	,
cord-285778-80baxwgc	126	18	as	as	IN
cord-285778-80baxwgc	126	19	described	describe	VBN
cord-285778-80baxwgc	126	20	in	in	IN
cord-285778-80baxwgc	126	21	detail	detail	NN
cord-285778-80baxwgc	126	22	in	in	IN
cord-285778-80baxwgc	126	23	Chapter	chapter	NN
cord-285778-80baxwgc	126	24	3	3	CD
cord-285778-80baxwgc	126	25	.	.	.
cord-285778-80baxwgc	127	1	When	when	WRB
cord-285778-80baxwgc	127	2	invaders	invader	NNS
cord-285778-80baxwgc	127	3	breach	breach	VBP
cord-285778-80baxwgc	127	4	anatomical	anatomical	JJ
cord-285778-80baxwgc	127	5	and	and	CC
cord-285778-80baxwgc	127	6	physiological	physiological	JJ
cord-285778-80baxwgc	127	7	barriers	barrier	NNS
cord-285778-80baxwgc	127	8	,	,	,
cord-285778-80baxwgc	127	9	innate	innate	JJ
cord-285778-80baxwgc	127	10	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	127	11	start	start	VBP
cord-285778-80baxwgc	127	12	to	to	TO
cord-285778-80baxwgc	127	13	take	take	VB
cord-285778-80baxwgc	127	14	action	action	NN
cord-285778-80baxwgc	127	15	as	as	IN
cord-285778-80baxwgc	127	16	a	a	DT
cord-285778-80baxwgc	127	17	result	result	NN
cord-285778-80baxwgc	127	18	of	of	IN
cord-285778-80baxwgc	127	19	pattern	pattern	NN
cord-285778-80baxwgc	127	20	recognition	recognition	NN
cord-285778-80baxwgc	127	21	mediated	mediate	VBN
cord-285778-80baxwgc	127	22	by	by	IN
cord-285778-80baxwgc	127	23	the	the	DT
cord-285778-80baxwgc	127	24	binding	binding	NN
cord-285778-80baxwgc	127	25	of	of	IN
cord-285778-80baxwgc	127	26	PRMs	prm	NNS
cord-285778-80baxwgc	127	27	to	to	IN
cord-285778-80baxwgc	127	28	PAMPs	pamp	NNS
cord-285778-80baxwgc	127	29	furnished	furnish	VBN
cord-285778-80baxwgc	127	30	by	by	IN
cord-285778-80baxwgc	127	31	pathogens	pathogen	NNS
cord-285778-80baxwgc	127	32	and	and	CC
cord-285778-80baxwgc	127	33	to	to	IN
cord-285778-80baxwgc	127	34	DAMPs	damp	NNS
cord-285778-80baxwgc	127	35	emanating	emanate	VBG
cord-285778-80baxwgc	127	36	from	from	IN
cord-285778-80baxwgc	127	37	damaged	damage	VBN
cord-285778-80baxwgc	127	38	host	host	NN
cord-285778-80baxwgc	127	39	cells	cell	NNS
cord-285778-80baxwgc	127	40	.	.	.
cord-285778-80baxwgc	128	1	As	as	IN
cord-285778-80baxwgc	128	2	introduced	introduce	VBN
cord-285778-80baxwgc	128	3	previously	previously	RB
cord-285778-80baxwgc	128	4	,	,	,
cord-285778-80baxwgc	128	5	and	and	CC
cord-285778-80baxwgc	128	6	as	as	IN
cord-285778-80baxwgc	128	7	illustrated	illustrate	VBN
cord-285778-80baxwgc	128	8	in	in	IN
cord-285778-80baxwgc	128	9	Figure	figure	NN
cord-285778-80baxwgc	128	10	1	1	CD
cord-285778-80baxwgc	128	11	-4	-4	NNS
cord-285778-80baxwgc	128	12	,	,	,
cord-285778-80baxwgc	128	13	PRMs	prm	NNS
cord-285778-80baxwgc	128	14	come	come	VBP
cord-285778-80baxwgc	128	15	in	in	IN
cord-285778-80baxwgc	128	16	several	several	JJ
cord-285778-80baxwgc	128	17	different	different	JJ
cord-285778-80baxwgc	128	18	forms	form	NNS
cord-285778-80baxwgc	128	19	,	,	,
cord-285778-80baxwgc	128	20	some	some	DT
cord-285778-80baxwgc	128	21	of	of	IN
cord-285778-80baxwgc	128	22	which	which	WDT
cord-285778-80baxwgc	128	23	are	be	VBP
cord-285778-80baxwgc	128	24	membrane	membrane	NN
cord-285778-80baxwgc	128	25	-	-	HYPH
cord-285778-80baxwgc	128	26	bound	bind	VBN
cord-285778-80baxwgc	128	27	and	and	CC
cord-285778-80baxwgc	128	28	others	other	NNS
cord-285778-80baxwgc	128	29	of	of	IN
cord-285778-80baxwgc	128	30	which	which	WDT
cord-285778-80baxwgc	128	31	are	be	VBP
cord-285778-80baxwgc	128	32	soluble	soluble	JJ
cord-285778-80baxwgc	128	33	.	.	.
cord-285778-80baxwgc	129	1	PRMs	prm	NNS
cord-285778-80baxwgc	129	2	that	that	WDT
cord-285778-80baxwgc	129	3	are	be	VBP
cord-285778-80baxwgc	129	4	expressed	express	VBN
cord-285778-80baxwgc	129	5	by	by	IN
cord-285778-80baxwgc	129	6	innate	innate	JJ
cord-285778-80baxwgc	129	7	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	129	8	are	be	VBP
cord-285778-80baxwgc	129	9	called	call	VBN
cord-285778-80baxwgc	129	10	pattern	pattern	NN
cord-285778-80baxwgc	129	11	recognition	recognition	NN
cord-285778-80baxwgc	129	12	receptors	receptor	NNS
cord-285778-80baxwgc	129	13	(	(	-LRB-
cord-285778-80baxwgc	129	14	PRRs	PRRs	NNP
cord-285778-80baxwgc	129	15	)	)	-RRB-
cord-285778-80baxwgc	129	16	.	.	.
cord-285778-80baxwgc	130	1	PRRs	PRRs	NNP
cord-285778-80baxwgc	130	2	are	be	VBP
cord-285778-80baxwgc	130	3	located	locate	VBN
cord-285778-80baxwgc	130	4	in	in	IN
cord-285778-80baxwgc	130	5	the	the	DT
cord-285778-80baxwgc	130	6	plasma	plasma	NN
cord-285778-80baxwgc	130	7	membrane	membrane	NN
cord-285778-80baxwgc	130	8	of	of	IN
cord-285778-80baxwgc	130	9	an	an	DT
cord-285778-80baxwgc	130	10	innate	innate	JJ
cord-285778-80baxwgc	130	11	leukocyte	leukocyte	NN
cord-285778-80baxwgc	130	12	,	,	,
cord-285778-80baxwgc	130	13	or	or	CC
cord-285778-80baxwgc	130	14	are	be	VBP
cord-285778-80baxwgc	130	15	soluble	soluble	JJ
cord-285778-80baxwgc	130	16	molecules	molecule	NNS
cord-285778-80baxwgc	130	17	free	free	JJ
cord-285778-80baxwgc	130	18	in	in	IN
cord-285778-80baxwgc	130	19	the	the	DT
cord-285778-80baxwgc	130	20	leukocyte	leukocyte	NN
cord-285778-80baxwgc	130	21	's	's	POS
cord-285778-80baxwgc	130	22	cytoplasm	cytoplasm	NN
cord-285778-80baxwgc	130	23	,	,	,
cord-285778-80baxwgc	130	24	or	or	CC
cord-285778-80baxwgc	130	25	are	be	VBP
cord-285778-80baxwgc	130	26	fixed	fix	VBN
cord-285778-80baxwgc	130	27	in	in	IN
cord-285778-80baxwgc	130	28	the	the	DT
cord-285778-80baxwgc	130	29	membranes	membrane	NNS
cord-285778-80baxwgc	130	30	of	of	IN
cord-285778-80baxwgc	130	31	intracellular	intracellular	JJ
cord-285778-80baxwgc	130	32	vesicles	vesicle	NNS
cord-285778-80baxwgc	130	33	called	call	VBN
cord-285778-80baxwgc	130	34	endosomes	endosome	NNS
cord-285778-80baxwgc	130	35	.	.	.
cord-285778-80baxwgc	131	1	Other	other	JJ
cord-285778-80baxwgc	131	2	PRMs	prm	NNS
cord-285778-80baxwgc	131	3	are	be	VBP
cord-285778-80baxwgc	131	4	made	make	VBN
cord-285778-80baxwgc	131	5	by	by	IN
cord-285778-80baxwgc	131	6	non	non	JJ
cord-285778-80baxwgc	131	7	-	-	JJ
cord-285778-80baxwgc	131	8	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	131	9	and	and	CC
cord-285778-80baxwgc	131	10	are	be	VBP
cord-285778-80baxwgc	131	11	present	present	JJ
cord-285778-80baxwgc	131	12	as	as	IN
cord-285778-80baxwgc	131	13	soluble	soluble	JJ
cord-285778-80baxwgc	131	14	molecules	molecule	NNS
cord-285778-80baxwgc	131	15	free	free	JJ
cord-285778-80baxwgc	131	16	in	in	IN
cord-285778-80baxwgc	131	17	the	the	DT
cord-285778-80baxwgc	131	18	extracellular	extracellular	JJ
cord-285778-80baxwgc	131	19	milieu	milieu	NN
cord-285778-80baxwgc	131	20	.	.	.
cord-285778-80baxwgc	132	1	When	when	WRB
cord-285778-80baxwgc	132	2	these	these	DT
cord-285778-80baxwgc	132	3	latter	latter	JJ
cord-285778-80baxwgc	132	4	PRMs	prm	NNS
cord-285778-80baxwgc	132	5	bind	bind	NN
cord-285778-80baxwgc	132	6	to	to	IN
cord-285778-80baxwgc	132	7	a	a	DT
cord-285778-80baxwgc	132	8	given	give	VBN
cord-285778-80baxwgc	132	9	PAMP	pamp	NN
cord-285778-80baxwgc	132	10	or	or	CC
cord-285778-80baxwgc	132	11	DAMP	damp	VB
cord-285778-80baxwgc	132	12	,	,	,
cord-285778-80baxwgc	132	13	they	-PRON-	PRP
cord-285778-80baxwgc	132	14	must	must	MD
cord-285778-80baxwgc	132	15	then	then	RB
cord-285778-80baxwgc	132	16	bind	bind	VB
cord-285778-80baxwgc	132	17	to	to	IN
cord-285778-80baxwgc	132	18	another	another	DT
cord-285778-80baxwgc	132	19	receptor	receptor	NN
cord-285778-80baxwgc	132	20	fixed	fix	VBN
cord-285778-80baxwgc	132	21	in	in	IN
cord-285778-80baxwgc	132	22	a	a	DT
cord-285778-80baxwgc	132	23	leukocyte	leukocyte	NN
cord-285778-80baxwgc	132	24	membrane	membrane	NN
cord-285778-80baxwgc	132	25	in	in	IN
cord-285778-80baxwgc	132	26	order	order	NN
cord-285778-80baxwgc	132	27	to	to	TO
cord-285778-80baxwgc	132	28	trigger	trigger	VB
cord-285778-80baxwgc	132	29	the	the	DT
cord-285778-80baxwgc	132	30	appropriate	appropriate	JJ
cord-285778-80baxwgc	132	31	clearance	clearance	NN
cord-285778-80baxwgc	132	32	response	response	NN
cord-285778-80baxwgc	132	33	.	.	.
cord-285778-80baxwgc	133	1	The	the	DT
cord-285778-80baxwgc	133	2	clearance	clearance	NN
cord-285778-80baxwgc	133	3	mechanisms	mechanism	NNS
cord-285778-80baxwgc	133	4	typically	typically	RB
cord-285778-80baxwgc	133	5	induced	induce	VBN
cord-285778-80baxwgc	133	6	following	follow	VBG
cord-285778-80baxwgc	133	7	PRM	PRM	NNP
cord-285778-80baxwgc	133	8	or	or	CC
cord-285778-80baxwgc	133	9	PRR	PRR	NNP
cord-285778-80baxwgc	133	10	engagement	engagement	NN
cord-285778-80baxwgc	133	11	by	by	IN
cord-285778-80baxwgc	133	12	a	a	DT
cord-285778-80baxwgc	133	13	DAMP	damp	JJ
cord-285778-80baxwgc	133	14	or	or	CC
cord-285778-80baxwgc	133	15	PAMP	PAMP	NNS
cord-285778-80baxwgc	133	16	are	be	VBP
cord-285778-80baxwgc	133	17	inflammation	inflammation	NN
cord-285778-80baxwgc	133	18	,	,	,
cord-285778-80baxwgc	133	19	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	133	20	,	,	,
cord-285778-80baxwgc	133	21	and/or	and/or	CC
cord-285778-80baxwgc	133	22	target	target	NN
cord-285778-80baxwgc	133	23	cell	cell	NN
cord-285778-80baxwgc	133	24	lysis	lysis	NN
cord-285778-80baxwgc	133	25	.	.	.
cord-285778-80baxwgc	134	1	A	a	DT
cord-285778-80baxwgc	134	2	brief	brief	JJ
cord-285778-80baxwgc	134	3	description	description	NN
cord-285778-80baxwgc	134	4	of	of	IN
cord-285778-80baxwgc	134	5	each	each	DT
cord-285778-80baxwgc	134	6	of	of	IN
cord-285778-80baxwgc	134	7	these	these	DT
cord-285778-80baxwgc	134	8	processes	process	NNS
cord-285778-80baxwgc	134	9	follows	follow	VBZ
cord-285778-80baxwgc	134	10	,	,	,
cord-285778-80baxwgc	134	11	with	with	IN
cord-285778-80baxwgc	134	12	more	more	JJR
cord-285778-80baxwgc	134	13	detail	detail	NN
cord-285778-80baxwgc	134	14	provided	provide	VBN
cord-285778-80baxwgc	134	15	in	in	IN
cord-285778-80baxwgc	134	16	Chapter	chapter	NN
cord-285778-80baxwgc	134	17	3	3	CD
cord-285778-80baxwgc	134	18	.	.	.
cord-285778-80baxwgc	135	1	When	when	WRB
cord-285778-80baxwgc	135	2	leukocyte	leukocyte	NN
cord-285778-80baxwgc	135	3	PRRs	prr	NNS
cord-285778-80baxwgc	135	4	are	be	VBP
cord-285778-80baxwgc	135	5	engaged	engage	VBN
cord-285778-80baxwgc	135	6	by	by	IN
cord-285778-80baxwgc	135	7	their	-PRON-	PRP$
cord-285778-80baxwgc	135	8	ligands	ligand	NNS
cord-285778-80baxwgc	135	9	,	,	,
cord-285778-80baxwgc	135	10	intracellular	intracellular	JJ
cord-285778-80baxwgc	135	11	signal	signal	NN
cord-285778-80baxwgc	135	12	transduction	transduction	NN
cord-285778-80baxwgc	135	13	leads	lead	VBZ
cord-285778-80baxwgc	135	14	to	to	IN
cord-285778-80baxwgc	135	15	the	the	DT
cord-285778-80baxwgc	135	16	induction	induction	NN
cord-285778-80baxwgc	135	17	of	of	IN
cord-285778-80baxwgc	135	18	new	new	JJ
cord-285778-80baxwgc	135	19	gene	gene	NN
cord-285778-80baxwgc	135	20	transcription	transcription	NN
cord-285778-80baxwgc	135	21	and	and	CC
cord-285778-80baxwgc	135	22	the	the	DT
cord-285778-80baxwgc	135	23	synthesis	synthesis	NN
cord-285778-80baxwgc	135	24	of	of	IN
cord-285778-80baxwgc	135	25	various	various	JJ
cord-285778-80baxwgc	135	26	"	"	``
cord-285778-80baxwgc	135	27	proinflammatory	proinflammatory	JJ
cord-285778-80baxwgc	135	28	"	"	''
cord-285778-80baxwgc	135	29	cytokines	cytokine	NNS
cord-285778-80baxwgc	135	30	.	.	.
cord-285778-80baxwgc	136	1	These	these	DT
cord-285778-80baxwgc	136	2	cytokines	cytokine	NNS
cord-285778-80baxwgc	136	3	in	in	IN
cord-285778-80baxwgc	136	4	turn	turn	NN
cord-285778-80baxwgc	136	5	drive	drive	NN
cord-285778-80baxwgc	136	6	events	event	NNS
cord-285778-80baxwgc	136	7	responsible	responsible	JJ
cord-285778-80baxwgc	136	8	for	for	IN
cord-285778-80baxwgc	136	9	the	the	DT
cord-285778-80baxwgc	136	10	influx	influx	NN
cord-285778-80baxwgc	136	11	of	of	IN
cord-285778-80baxwgc	136	12	first	first	JJ
cord-285778-80baxwgc	136	13	innate	innate	JJ
cord-285778-80baxwgc	136	14	and	and	CC
cord-285778-80baxwgc	136	15	later	later	RB
cord-285778-80baxwgc	136	16	(	(	-LRB-
cord-285778-80baxwgc	136	17	if	if	IN
cord-285778-80baxwgc	136	18	necessary	necessary	JJ
cord-285778-80baxwgc	136	19	)	)	-RRB-
cord-285778-80baxwgc	136	20	adaptive	adaptive	JJ
cord-285778-80baxwgc	136	21	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	136	22	into	into	IN
cord-285778-80baxwgc	136	23	the	the	DT
cord-285778-80baxwgc	136	24	site	site	NN
cord-285778-80baxwgc	136	25	of	of	IN
cord-285778-80baxwgc	136	26	injury	injury	NN
cord-285778-80baxwgc	136	27	 	 	_SP
cord-285778-80baxwgc	136	28	When	when	WRB
cord-285778-80baxwgc	136	29	PAMPs	pamp	NNS
cord-285778-80baxwgc	136	30	on	on	IN
cord-285778-80baxwgc	136	31	a	a	DT
cord-285778-80baxwgc	136	32	pathogen	pathogen	NN
cord-285778-80baxwgc	136	33	bind	bind	NN
cord-285778-80baxwgc	136	34	to	to	IN
cord-285778-80baxwgc	136	35	the	the	DT
cord-285778-80baxwgc	136	36	PRRs	prr	NNS
cord-285778-80baxwgc	136	37	of	of	IN
cord-285778-80baxwgc	136	38	an	an	DT
cord-285778-80baxwgc	136	39	innate	innate	JJ
cord-285778-80baxwgc	136	40	leukocyte	leukocyte	NN
cord-285778-80baxwgc	136	41	,	,	,
cord-285778-80baxwgc	136	42	the	the	DT
cord-285778-80baxwgc	136	43	cell	cell	NN
cord-285778-80baxwgc	136	44	becomes	become	VBZ
cord-285778-80baxwgc	136	45	activated	activate	VBN
cord-285778-80baxwgc	136	46	and	and	CC
cord-285778-80baxwgc	136	47	attempts	attempt	VBZ
cord-285778-80baxwgc	136	48	to	to	TO
cord-285778-80baxwgc	136	49	clear	clear	VB
cord-285778-80baxwgc	136	50	the	the	DT
cord-285778-80baxwgc	136	51	pathogen	pathogen	NN
cord-285778-80baxwgc	136	52	through	through	IN
cord-285778-80baxwgc	136	53	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	136	54	,	,	,
cord-285778-80baxwgc	136	55	target	target	NN
cord-285778-80baxwgc	136	56	cell	cell	NN
cord-285778-80baxwgc	136	57	lysis	lysis	NN
cord-285778-80baxwgc	136	58	,	,	,
cord-285778-80baxwgc	136	59	and/	and/	CD
cord-285778-80baxwgc	136	60	or	or	CC
cord-285778-80baxwgc	136	61	the	the	DT
cord-285778-80baxwgc	136	62	induction	induction	NN
cord-285778-80baxwgc	136	63	of	of	IN
cord-285778-80baxwgc	136	64	inflammation	inflammation	NN
cord-285778-80baxwgc	136	65	.	.	.
cord-285778-80baxwgc	137	1	The	the	DT
cord-285778-80baxwgc	137	2	PRR	PRR	NNP
cord-285778-80baxwgc	137	3	may	may	MD
cord-285778-80baxwgc	137	4	be	be	VB
cord-285778-80baxwgc	137	5	expressed	express	VBN
cord-285778-80baxwgc	137	6	on	on	IN
cord-285778-80baxwgc	137	7	the	the	DT
cord-285778-80baxwgc	137	8	leukocyte	leukocyte	NN
cord-285778-80baxwgc	137	9	surface	surface	NN
cord-285778-80baxwgc	137	10	,	,	,
cord-285778-80baxwgc	137	11	on	on	IN
cord-285778-80baxwgc	137	12	its	-PRON-	PRP$
cord-285778-80baxwgc	137	13	endosomal	endosomal	JJ
cord-285778-80baxwgc	137	14	membranes	membrane	NNS
cord-285778-80baxwgc	137	15	or	or	CC
cord-285778-80baxwgc	137	16	in	in	IN
cord-285778-80baxwgc	137	17	its	-PRON-	PRP$
cord-285778-80baxwgc	137	18	cytoplasm	cytoplasm	NN
cord-285778-80baxwgc	137	19	.	.	.
cord-285778-80baxwgc	138	1	or	or	CC
cord-285778-80baxwgc	138	2	infection	infection	NN
cord-285778-80baxwgc	138	3	.	.	.
cord-285778-80baxwgc	139	1	This	this	DT
cord-285778-80baxwgc	139	2	influx	influx	NN
cord-285778-80baxwgc	139	3	is	be	VBZ
cord-285778-80baxwgc	139	4	part	part	NN
cord-285778-80baxwgc	139	5	of	of	IN
cord-285778-80baxwgc	139	6	a	a	DT
cord-285778-80baxwgc	139	7	process	process	NN
cord-285778-80baxwgc	139	8	called	call	VBN
cord-285778-80baxwgc	139	9	inflammation	inflammation	NN
cord-285778-80baxwgc	139	10	or	or	CC
cord-285778-80baxwgc	139	11	an	an	DT
cord-285778-80baxwgc	139	12	inflammatory	inflammatory	JJ
cord-285778-80baxwgc	139	13	response	response	NN
cord-285778-80baxwgc	139	14	,	,	,
cord-285778-80baxwgc	139	15	and	and	CC
cord-285778-80baxwgc	139	16	the	the	DT
cord-285778-80baxwgc	139	17	redness	redness	NN
cord-285778-80baxwgc	139	18	and	and	CC
cord-285778-80baxwgc	139	19	swelling	swell	VBG
cord-285778-80baxwgc	139	20	we	-PRON-	PRP
cord-285778-80baxwgc	139	21	commonly	commonly	RB
cord-285778-80baxwgc	139	22	associate	associate	VBP
cord-285778-80baxwgc	139	23	with	with	IN
cord-285778-80baxwgc	139	24	inflammation	inflammation	NN
cord-285778-80baxwgc	139	25	are	be	VBP
cord-285778-80baxwgc	139	26	its	-PRON-	PRP$
cord-285778-80baxwgc	139	27	outward	outward	JJ
cord-285778-80baxwgc	139	28	physical	physical	JJ
cord-285778-80baxwgc	139	29	signs	sign	NNS
cord-285778-80baxwgc	139	30	.	.	.
cord-285778-80baxwgc	140	1	This	this	DT
cord-285778-80baxwgc	140	2	inflammation	inflammation	NN
cord-285778-80baxwgc	140	3	is	be	VBZ
cord-285778-80baxwgc	140	4	normal	normal	JJ
cord-285778-80baxwgc	140	5	and	and	CC
cord-285778-80baxwgc	140	6	helpful	helpful	JJ
cord-285778-80baxwgc	140	7	,	,	,
cord-285778-80baxwgc	140	8	and	and	CC
cord-285778-80baxwgc	140	9	,	,	,
cord-285778-80baxwgc	140	10	when	when	WRB
cord-285778-80baxwgc	140	11	properly	properly	RB
cord-285778-80baxwgc	140	12	regulated	regulate	VBN
cord-285778-80baxwgc	140	13	,	,	,
cord-285778-80baxwgc	140	14	promotes	promote	VBZ
cord-285778-80baxwgc	140	15	a	a	DT
cord-285778-80baxwgc	140	16	localized	localized	JJ
cord-285778-80baxwgc	140	17	gathering	gathering	NN
cord-285778-80baxwgc	140	18	of	of	IN
cord-285778-80baxwgc	140	19	the	the	DT
cord-285778-80baxwgc	140	20	cells	cell	NNS
cord-285778-80baxwgc	140	21	and	and	CC
cord-285778-80baxwgc	140	22	molecules	molecule	NNS
cord-285778-80baxwgc	140	23	necessary	necessary	JJ
cord-285778-80baxwgc	140	24	to	to	TO
cord-285778-80baxwgc	140	25	repair	repair	VB
cord-285778-80baxwgc	140	26	tissue	tissue	NN
cord-285778-80baxwgc	140	27	damage	damage	NN
cord-285778-80baxwgc	140	28	and	and	CC
cord-285778-80baxwgc	140	29	clear	clear	JJ
cord-285778-80baxwgc	140	30	pathogens	pathogen	NNS
cord-285778-80baxwgc	140	31	.	.	.
cord-285778-80baxwgc	141	1	Once	once	IN
cord-285778-80baxwgc	141	2	the	the	DT
cord-285778-80baxwgc	141	3	threat	threat	NN
cord-285778-80baxwgc	141	4	is	be	VBZ
cord-285778-80baxwgc	141	5	eliminated	eliminate	VBN
cord-285778-80baxwgc	141	6	,	,	,
cord-285778-80baxwgc	141	7	the	the	DT
cord-285778-80baxwgc	141	8	inflammation	inflammation	NN
cord-285778-80baxwgc	141	9	resolves	resolve	VBZ
cord-285778-80baxwgc	141	10	naturally	naturally	RB
cord-285778-80baxwgc	141	11	with	with	IN
cord-285778-80baxwgc	141	12	time	time	NN
cord-285778-80baxwgc	141	13	.	.	.
cord-285778-80baxwgc	142	1	However	however	RB
cord-285778-80baxwgc	142	2	,	,	,
cord-285778-80baxwgc	142	3	if	if	IN
cord-285778-80baxwgc	142	4	the	the	DT
cord-285778-80baxwgc	142	5	inflammation	inflammation	NN
cord-285778-80baxwgc	142	6	fails	fail	VBZ
cord-285778-80baxwgc	142	7	to	to	TO
cord-285778-80baxwgc	142	8	resolve	resolve	VB
cord-285778-80baxwgc	142	9	and	and	CC
cord-285778-80baxwgc	142	10	becomes	become	VBZ
cord-285778-80baxwgc	142	11	chronic	chronic	JJ
cord-285778-80baxwgc	142	12	,	,	,
cord-285778-80baxwgc	142	13	it	-PRON-	PRP
cord-285778-80baxwgc	142	14	may	may	MD
cord-285778-80baxwgc	142	15	become	become	VB
cord-285778-80baxwgc	142	16	pathological	pathological	JJ
cord-285778-80baxwgc	142	17	.	.	.
cord-285778-80baxwgc	143	1	The	the	DT
cord-285778-80baxwgc	143	2	powerful	powerful	JJ
cord-285778-80baxwgc	143	3	molecules	molecule	NNS
cord-285778-80baxwgc	143	4	secreted	secrete	VBN
cord-285778-80baxwgc	143	5	by	by	IN
cord-285778-80baxwgc	143	6	the	the	DT
cord-285778-80baxwgc	143	7	innate	innate	JJ
cord-285778-80baxwgc	143	8	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	143	9	participating	participate	VBG
cord-285778-80baxwgc	143	10	in	in	IN
cord-285778-80baxwgc	143	11	the	the	DT
cord-285778-80baxwgc	143	12	inflammatory	inflammatory	JJ
cord-285778-80baxwgc	143	13	response	response	NN
cord-285778-80baxwgc	143	14	can	can	MD
cord-285778-80baxwgc	143	15	eventually	eventually	RB
cord-285778-80baxwgc	143	16	cause	cause	VB
cord-285778-80baxwgc	143	17	tissue	tissue	NN
cord-285778-80baxwgc	143	18	damage	damage	NN
cord-285778-80baxwgc	143	19	and	and	CC
cord-285778-80baxwgc	143	20	impair	impair	VB
cord-285778-80baxwgc	143	21	immune	immune	JJ
cord-285778-80baxwgc	143	22	system	system	NN
cord-285778-80baxwgc	143	23	function	function	NN
cord-285778-80baxwgc	143	24	if	if	IN
cord-285778-80baxwgc	143	25	left	leave	VBN
cord-285778-80baxwgc	143	26	to	to	TO
cord-285778-80baxwgc	143	27	operate	operate	VB
cord-285778-80baxwgc	143	28	unchecked	unchecked	JJ
cord-285778-80baxwgc	143	29	.	.	.
cord-285778-80baxwgc	144	1	Thus	thus	RB
cord-285778-80baxwgc	144	2	,	,	,
cord-285778-80baxwgc	144	3	properly	properly	RB
cord-285778-80baxwgc	144	4	controlled	control	VBN
cord-285778-80baxwgc	144	5	inflammation	inflammation	NN
cord-285778-80baxwgc	144	6	is	be	VBZ
cord-285778-80baxwgc	144	7	part	part	NN
cord-285778-80baxwgc	144	8	of	of	IN
cord-285778-80baxwgc	144	9	a	a	DT
cord-285778-80baxwgc	144	10	healthy	healthy	JJ
cord-285778-80baxwgc	144	11	innate	innate	JJ
cord-285778-80baxwgc	144	12	response	response	NN
cord-285778-80baxwgc	144	13	and	and	CC
cord-285778-80baxwgc	144	14	essential	essential	JJ
cord-285778-80baxwgc	144	15	for	for	IN
cord-285778-80baxwgc	144	16	homeostasis	homeostasis	NN
cord-285778-80baxwgc	144	17	,	,	,
cord-285778-80baxwgc	144	18	whereas	whereas	IN
cord-285778-80baxwgc	144	19	excessive	excessive	JJ
cord-285778-80baxwgc	144	20	or	or	CC
cord-285778-80baxwgc	144	21	prolonged	prolonged	JJ
cord-285778-80baxwgc	144	22	inflammation	inflammation	NN
cord-285778-80baxwgc	144	23	is	be	VBZ
cord-285778-80baxwgc	144	24	immunopathic	immunopathic	JJ
cord-285778-80baxwgc	144	25	and	and	CC
cord-285778-80baxwgc	144	26	undermines	undermine	VBZ
cord-285778-80baxwgc	144	27	homeostasis	homeostasis	NN
cord-285778-80baxwgc	144	28	.	.	.
cord-285778-80baxwgc	145	1	Innate	innate	JJ
cord-285778-80baxwgc	145	2	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	145	3	frequently	frequently	RB
cord-285778-80baxwgc	145	4	use	use	VBP
cord-285778-80baxwgc	145	5	a	a	DT
cord-285778-80baxwgc	145	6	sophisticated	sophisticated	JJ
cord-285778-80baxwgc	145	7	means	mean	NNS
cord-285778-80baxwgc	145	8	of	of	IN
cord-285778-80baxwgc	145	9	engulfing	engulf	VBG
cord-285778-80baxwgc	145	10	entities	entity	NNS
cord-285778-80baxwgc	145	11	that	that	WDT
cord-285778-80baxwgc	145	12	is	be	VBZ
cord-285778-80baxwgc	145	13	called	call	VBN
cord-285778-80baxwgc	145	14	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	145	15	(	(	-LRB-
cord-285778-80baxwgc	145	16	"	"	``
cord-285778-80baxwgc	145	17	eating	eat	VBG
cord-285778-80baxwgc	145	18	of	of	IN
cord-285778-80baxwgc	145	19	cells	cell	NNS
cord-285778-80baxwgc	145	20	"	"	''
cord-285778-80baxwgc	145	21	)	)	-RRB-
cord-285778-80baxwgc	145	22	.	.	.
cord-285778-80baxwgc	146	1	Phagocytosis	Phagocytosis	NNP
cord-285778-80baxwgc	146	2	is	be	VBZ
cord-285778-80baxwgc	146	3	carried	carry	VBN
cord-285778-80baxwgc	146	4	out	out	RP
cord-285778-80baxwgc	146	5	primarily	primarily	RB
cord-285778-80baxwgc	146	6	by	by	IN
cord-285778-80baxwgc	146	7	three	three	CD
cord-285778-80baxwgc	146	8	types	type	NNS
cord-285778-80baxwgc	146	9	of	of	IN
cord-285778-80baxwgc	146	10	PRR	PRR	NNP
cord-285778-80baxwgc	146	11	-	-	HYPH
cord-285778-80baxwgc	146	12	expressing	express	VBG
cord-285778-80baxwgc	146	13	cells	cell	NNS
cord-285778-80baxwgc	146	14	:	:	:
cord-285778-80baxwgc	146	15	neutrophils	neutrophil	NNS
cord-285778-80baxwgc	146	16	,	,	,
cord-285778-80baxwgc	146	17	macrophages	macrophage	NNS
cord-285778-80baxwgc	146	18	and	and	CC
cord-285778-80baxwgc	146	19	dendritic	dendritic	JJ
cord-285778-80baxwgc	146	20	cells	cell	NNS
cord-285778-80baxwgc	146	21	(	(	-LRB-
cord-285778-80baxwgc	146	22	DCs	DCs	NNP
cord-285778-80baxwgc	146	23	)	)	-RRB-
cord-285778-80baxwgc	146	24	;	;	:
cord-285778-80baxwgc	146	25	these	these	DT
cord-285778-80baxwgc	146	26	cell	cell	NN
cord-285778-80baxwgc	146	27	types	type	NNS
cord-285778-80baxwgc	146	28	are	be	VBP
cord-285778-80baxwgc	146	29	consequently	consequently	RB
cord-285778-80baxwgc	146	30	known	know	VBN
cord-285778-80baxwgc	146	31	as	as	IN
cord-285778-80baxwgc	146	32	phagocytes	phagocyte	NNS
cord-285778-80baxwgc	146	33	.	.	.
cord-285778-80baxwgc	147	1	Neutrophils	neutrophils	NN
cord-285778-80baxwgc	147	2	mainly	mainly	RB
cord-285778-80baxwgc	147	3	engulf	engulf	VBP
cord-285778-80baxwgc	147	4	and	and	CC
cord-285778-80baxwgc	147	5	destroy	destroy	VB
cord-285778-80baxwgc	147	6	pathogens	pathogen	NNS
cord-285778-80baxwgc	147	7	,	,	,
cord-285778-80baxwgc	147	8	while	while	IN
cord-285778-80baxwgc	147	9	macrophages	macrophage	NNS
cord-285778-80baxwgc	147	10	and	and	CC
cord-285778-80baxwgc	147	11	DCs	dc	NNS
cord-285778-80baxwgc	147	12	engulf	engulf	VBP
cord-285778-80baxwgc	147	13	not	not	RB
cord-285778-80baxwgc	147	14	only	only	RB
cord-285778-80baxwgc	147	15	pathogens	pathogen	NNS
cord-285778-80baxwgc	147	16	but	but	CC
cord-285778-80baxwgc	147	17	also	also	RB
cord-285778-80baxwgc	147	18	dead	dead	JJ
cord-285778-80baxwgc	147	19	host	host	NN
cord-285778-80baxwgc	147	20	cells	cell	NNS
cord-285778-80baxwgc	147	21	,	,	,
cord-285778-80baxwgc	147	22	cellular	cellular	JJ
cord-285778-80baxwgc	147	23	debris	debris	NN
cord-285778-80baxwgc	147	24	and	and	CC
cord-285778-80baxwgc	147	25	host	host	NN
cord-285778-80baxwgc	147	26	macromolecules	macromolecule	NNS
cord-285778-80baxwgc	147	27	.	.	.
cord-285778-80baxwgc	148	1	The	the	DT
cord-285778-80baxwgc	148	2	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	148	3	of	of	IN
cord-285778-80baxwgc	148	4	foreign	foreign	JJ
cord-285778-80baxwgc	148	5	entities	entity	NNS
cord-285778-80baxwgc	148	6	by	by	IN
cord-285778-80baxwgc	148	7	macrophages	macrophage	NNS
cord-285778-80baxwgc	148	8	and	and	CC
cord-285778-80baxwgc	148	9	DCs	dc	NNS
cord-285778-80baxwgc	148	10	allows	allow	VBZ
cord-285778-80baxwgc	148	11	these	these	DT
cord-285778-80baxwgc	148	12	cells	cell	NNS
cord-285778-80baxwgc	148	13	to	to	IN
cord-285778-80baxwgc	148	14	"	"	``
cord-285778-80baxwgc	148	15	present	present	JJ
cord-285778-80baxwgc	148	16	"	"	''
cord-285778-80baxwgc	148	17	unique	unique	JJ
cord-285778-80baxwgc	148	18	antigens	antigen	NNS
cord-285778-80baxwgc	148	19	from	from	IN
cord-285778-80baxwgc	148	20	this	this	DT
cord-285778-80baxwgc	148	21	material	material	NN
cord-285778-80baxwgc	148	22	on	on	IN
cord-285778-80baxwgc	148	23	their	-PRON-	PRP$
cord-285778-80baxwgc	148	24	cell	cell	NN
cord-285778-80baxwgc	148	25	surfaces	surface	NNS
cord-285778-80baxwgc	148	26	in	in	IN
cord-285778-80baxwgc	148	27	such	such	PDT
cord-285778-80baxwgc	148	28	a	a	DT
cord-285778-80baxwgc	148	29	way	way	NN
cord-285778-80baxwgc	148	30	that	that	WDT
cord-285778-80baxwgc	148	31	the	the	DT
cord-285778-80baxwgc	148	32	antigens	antigen	NNS
cord-285778-80baxwgc	148	33	can	can	MD
cord-285778-80baxwgc	148	34	be	be	VB
cord-285778-80baxwgc	148	35	recognized	recognize	VBN
cord-285778-80baxwgc	148	36	by	by	IN
cord-285778-80baxwgc	148	37	adaptive	adaptive	JJ
cord-285778-80baxwgc	148	38	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	148	39	that	that	WDT
cord-285778-80baxwgc	148	40	have	have	VBP
cord-285778-80baxwgc	148	41	been	be	VBN
cord-285778-80baxwgc	148	42	drawn	draw	VBN
cord-285778-80baxwgc	148	43	to	to	IN
cord-285778-80baxwgc	148	44	the	the	DT
cord-285778-80baxwgc	148	45	site	site	NN
cord-285778-80baxwgc	148	46	of	of	IN
cord-285778-80baxwgc	148	47	inflammation	inflammation	NN
cord-285778-80baxwgc	148	48	.	.	.
cord-285778-80baxwgc	149	1	These	these	DT
cord-285778-80baxwgc	149	2	cells	cell	NNS
cord-285778-80baxwgc	149	3	are	be	VBP
cord-285778-80baxwgc	149	4	then	then	RB
cord-285778-80baxwgc	149	5	activated	activate	VBN
cord-285778-80baxwgc	149	6	and	and	CC
cord-285778-80baxwgc	149	7	mediate	mediate	VB
cord-285778-80baxwgc	149	8	antigen	antigen	NN
cord-285778-80baxwgc	149	9	-	-	HYPH
cord-285778-80baxwgc	149	10	specific	specific	JJ
cord-285778-80baxwgc	149	11	protection	protection	NN
cord-285778-80baxwgc	149	12	.	.	.
cord-285778-80baxwgc	150	1	Cancer	cancer	NN
cord-285778-80baxwgc	150	2	cells	cell	NNS
cord-285778-80baxwgc	150	3	and	and	CC
cord-285778-80baxwgc	150	4	cells	cell	NNS
cord-285778-80baxwgc	150	5	infected	infect	VBN
cord-285778-80baxwgc	150	6	with	with	IN
cord-285778-80baxwgc	150	7	intracellular	intracellular	JJ
cord-285778-80baxwgc	150	8	pathogens	pathogen	NNS
cord-285778-80baxwgc	150	9	frequently	frequently	RB
cord-285778-80baxwgc	150	10	express	express	VBP
cord-285778-80baxwgc	150	11	certain	certain	JJ
cord-285778-80baxwgc	150	12	DAMPs	damp	NNS
cord-285778-80baxwgc	150	13	and/or	and/or	CC
cord-285778-80baxwgc	150	14	PAMPs	pamp	NNS
cord-285778-80baxwgc	150	15	on	on	IN
cord-285778-80baxwgc	150	16	their	-PRON-	PRP$
cord-285778-80baxwgc	150	17	cell	cell	NN
cord-285778-80baxwgc	150	18	surfaces	surface	NNS
cord-285778-80baxwgc	150	19	that	that	WDT
cord-285778-80baxwgc	150	20	mark	mark	VBP
cord-285778-80baxwgc	150	21	them	-PRON-	PRP
cord-285778-80baxwgc	150	22	as	as	IN
cord-285778-80baxwgc	150	23	"	"	``
cord-285778-80baxwgc	150	24	target	target	NN
cord-285778-80baxwgc	150	25	cells	cell	NNS
cord-285778-80baxwgc	150	26	"	"	''
cord-285778-80baxwgc	150	27	for	for	IN
cord-285778-80baxwgc	150	28	destruction	destruction	NN
cord-285778-80baxwgc	150	29	by	by	IN
cord-285778-80baxwgc	150	30	cells	cell	NNS
cord-285778-80baxwgc	150	31	of	of	IN
cord-285778-80baxwgc	150	32	the	the	DT
cord-285778-80baxwgc	150	33	innate	innate	JJ
cord-285778-80baxwgc	150	34	system	system	NN
cord-285778-80baxwgc	150	35	.	.	.
cord-285778-80baxwgc	151	1	When	when	WRB
cord-285778-80baxwgc	151	2	these	these	DT
cord-285778-80baxwgc	151	3	molecules	molecule	NNS
cord-285778-80baxwgc	151	4	are	be	VBP
cord-285778-80baxwgc	151	5	recognized	recognize	VBN
cord-285778-80baxwgc	151	6	and	and	CC
cord-285778-80baxwgc	151	7	bound	bind	VBN
cord-285778-80baxwgc	151	8	by	by	IN
cord-285778-80baxwgc	151	9	PRRs	prr	NNS
cord-285778-80baxwgc	151	10	of	of	IN
cord-285778-80baxwgc	151	11	innate	innate	JJ
cord-285778-80baxwgc	151	12	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	151	13	,	,	,
cord-285778-80baxwgc	151	14	complex	complex	JJ
cord-285778-80baxwgc	151	15	processes	process	NNS
cord-285778-80baxwgc	151	16	are	be	VBP
cord-285778-80baxwgc	151	17	initiated	initiate	VBN
cord-285778-80baxwgc	151	18	that	that	DT
cord-285778-80baxwgc	151	19	result	result	NN
cord-285778-80baxwgc	151	20	in	in	IN
cord-285778-80baxwgc	151	21	the	the	DT
cord-285778-80baxwgc	151	22	lysis	lysis	NN
cord-285778-80baxwgc	151	23	of	of	IN
cord-285778-80baxwgc	151	24	the	the	DT
cord-285778-80baxwgc	151	25	cancer	cancer	NN
cord-285778-80baxwgc	151	26	cell	cell	NN
cord-285778-80baxwgc	151	27	or	or	CC
cord-285778-80baxwgc	151	28	infected	infected	JJ
cord-285778-80baxwgc	151	29	cell	cell	NN
cord-285778-80baxwgc	151	30	,	,	,
cord-285778-80baxwgc	151	31	preventing	prevent	VBG
cord-285778-80baxwgc	151	32	it	-PRON-	PRP
cord-285778-80baxwgc	151	33	from	from	IN
cord-285778-80baxwgc	151	34	causing	cause	VBG
cord-285778-80baxwgc	151	35	further	further	JJ
cord-285778-80baxwgc	151	36	harm	harm	NN
cord-285778-80baxwgc	151	37	to	to	IN
cord-285778-80baxwgc	151	38	the	the	DT
cord-285778-80baxwgc	151	39	body	body	NN
cord-285778-80baxwgc	151	40	.	.	.
cord-285778-80baxwgc	152	1	These	these	DT
cord-285778-80baxwgc	152	2	types	type	NNS
cord-285778-80baxwgc	152	3	of	of	IN
cord-285778-80baxwgc	152	4	innate	innate	JJ
cord-285778-80baxwgc	152	5	responses	response	NNS
cord-285778-80baxwgc	152	6	are	be	VBP
cord-285778-80baxwgc	152	7	carried	carry	VBN
cord-285778-80baxwgc	152	8	out	out	RP
cord-285778-80baxwgc	152	9	primarily	primarily	RB
cord-285778-80baxwgc	152	10	by	by	IN
cord-285778-80baxwgc	152	11	neutrophils	neutrophil	NNS
cord-285778-80baxwgc	152	12	,	,	,
cord-285778-80baxwgc	152	13	macrophages	macrophage	NNS
cord-285778-80baxwgc	152	14	and	and	CC
cord-285778-80baxwgc	152	15	another	another	DT
cord-285778-80baxwgc	152	16	type	type	NN
cord-285778-80baxwgc	152	17	of	of	IN
cord-285778-80baxwgc	152	18	innate	innate	JJ
cord-285778-80baxwgc	152	19	leukocyte	leukocyte	NN
cord-285778-80baxwgc	152	20	called	call	VBN
cord-285778-80baxwgc	152	21	a	a	DT
cord-285778-80baxwgc	152	22	natural	natural	JJ
cord-285778-80baxwgc	152	23	killer	killer	NN
cord-285778-80baxwgc	152	24	cell	cell	NN
cord-285778-80baxwgc	152	25	(	(	-LRB-
cord-285778-80baxwgc	152	26	NK	NK	NNP
cord-285778-80baxwgc	152	27	cell	cell	NN
cord-285778-80baxwgc	152	28	)	)	-RRB-
cord-285778-80baxwgc	152	29	.	.	.
cord-285778-80baxwgc	153	1	In	in	IN
cord-285778-80baxwgc	153	2	this	this	DT
cord-285778-80baxwgc	153	3	section	section	NN
cord-285778-80baxwgc	153	4	,	,	,
cord-285778-80baxwgc	153	5	we	-PRON-	PRP
cord-285778-80baxwgc	153	6	introduce	introduce	VBP
cord-285778-80baxwgc	153	7	the	the	DT
cord-285778-80baxwgc	153	8	main	main	JJ
cord-285778-80baxwgc	153	9	features	feature	NNS
cord-285778-80baxwgc	153	10	of	of	IN
cord-285778-80baxwgc	153	11	adaptive	adaptive	JJ
cord-285778-80baxwgc	153	12	immunity	immunity	NN
cord-285778-80baxwgc	153	13	.	.	.
cord-285778-80baxwgc	154	1	The	the	DT
cord-285778-80baxwgc	154	2	adaptive	adaptive	JJ
cord-285778-80baxwgc	154	3	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	154	4	referred	refer	VBN
cord-285778-80baxwgc	154	5	to	to	IN
cord-285778-80baxwgc	154	6	in	in	IN
cord-285778-80baxwgc	154	7	previous	previous	JJ
cord-285778-80baxwgc	154	8	sections	section	NNS
cord-285778-80baxwgc	154	9	are	be	VBP
cord-285778-80baxwgc	154	10	called	call	VBN
cord-285778-80baxwgc	154	11	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	154	12	.	.	.
cord-285778-80baxwgc	155	1	Lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	155	2	are	be	VBP
cord-285778-80baxwgc	155	3	categorized	categorize	VBN
cord-285778-80baxwgc	155	4	as	as	IN
cord-285778-80baxwgc	155	5	either	either	DT
cord-285778-80baxwgc	155	6	B	b	NN
cord-285778-80baxwgc	155	7	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	155	8	(	(	-LRB-
cord-285778-80baxwgc	155	9	B	b	NN
cord-285778-80baxwgc	155	10	cells	cell	NNS
cord-285778-80baxwgc	155	11	)	)	-RRB-
cord-285778-80baxwgc	155	12	or	or	CC
cord-285778-80baxwgc	155	13	T	t	NN
cord-285778-80baxwgc	155	14	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	155	15	(	(	-LRB-
cord-285778-80baxwgc	155	16	T	t	NN
cord-285778-80baxwgc	155	17	cells	cell	NNS
cord-285778-80baxwgc	155	18	)	)	-RRB-
cord-285778-80baxwgc	155	19	.	.	.
cord-285778-80baxwgc	156	1	The	the	DT
cord-285778-80baxwgc	156	2	fundamental	fundamental	JJ
cord-285778-80baxwgc	156	3	functional	functional	JJ
cord-285778-80baxwgc	156	4	and	and	CC
cord-285778-80baxwgc	156	5	developmental	developmental	JJ
cord-285778-80baxwgc	156	6	characteristics	characteristic	NNS
cord-285778-80baxwgc	156	7	of	of	IN
cord-285778-80baxwgc	156	8	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	156	9	are	be	VBP
cord-285778-80baxwgc	156	10	responsible	responsible	JJ
cord-285778-80baxwgc	156	11	for	for	IN
cord-285778-80baxwgc	156	12	the	the	DT
cord-285778-80baxwgc	156	13	specificity	specificity	NN
cord-285778-80baxwgc	156	14	,	,	,
cord-285778-80baxwgc	156	15	division	division	NN
cord-285778-80baxwgc	156	16	of	of	IN
cord-285778-80baxwgc	156	17	labor	labor	NN
cord-285778-80baxwgc	156	18	,	,	,
cord-285778-80baxwgc	156	19	memory	memory	NN
cord-285778-80baxwgc	156	20	,	,	,
cord-285778-80baxwgc	156	21	diversity	diversity	NN
cord-285778-80baxwgc	156	22	and	and	CC
cord-285778-80baxwgc	156	23	tolerance	tolerance	NN
cord-285778-80baxwgc	156	24	of	of	IN
cord-285778-80baxwgc	156	25	the	the	DT
cord-285778-80baxwgc	156	26	adaptive	adaptive	JJ
cord-285778-80baxwgc	156	27	response	response	NN
cord-285778-80baxwgc	156	28	.	.	.
cord-285778-80baxwgc	157	1	Each	each	DT
cord-285778-80baxwgc	157	2	of	of	IN
cord-285778-80baxwgc	157	3	these	these	DT
cord-285778-80baxwgc	157	4	important	important	JJ
cord-285778-80baxwgc	157	5	concepts	concept	NNS
cord-285778-80baxwgc	157	6	is	be	VBZ
cord-285778-80baxwgc	157	7	introduced	introduce	VBN
cord-285778-80baxwgc	157	8	here	here	RB
cord-285778-80baxwgc	157	9	as	as	IN
cord-285778-80baxwgc	157	10	a	a	DT
cord-285778-80baxwgc	157	11	prelude	prelude	NN
cord-285778-80baxwgc	157	12	to	to	IN
cord-285778-80baxwgc	157	13	more	more	RBR
cord-285778-80baxwgc	157	14	detailed	detailed	JJ
cord-285778-80baxwgc	157	15	discussions	discussion	NNS
cord-285778-80baxwgc	157	16	of	of	IN
cord-285778-80baxwgc	157	17	these	these	DT
cord-285778-80baxwgc	157	18	topics	topic	NNS
cord-285778-80baxwgc	157	19	in	in	IN
cord-285778-80baxwgc	157	20	later	later	JJ
cord-285778-80baxwgc	157	21	chapters	chapter	NNS
cord-285778-80baxwgc	157	22	.	.	.
cord-285778-80baxwgc	158	1	The	the	DT
cord-285778-80baxwgc	158	2	specificity	specificity	NN
cord-285778-80baxwgc	158	3	of	of	IN
cord-285778-80baxwgc	158	4	an	an	DT
cord-285778-80baxwgc	158	5	adaptive	adaptive	JJ
cord-285778-80baxwgc	158	6	immune	immune	JJ
cord-285778-80baxwgc	158	7	response	response	NN
cord-285778-80baxwgc	158	8	for	for	IN
cord-285778-80baxwgc	158	9	a	a	DT
cord-285778-80baxwgc	158	10	particular	particular	JJ
cord-285778-80baxwgc	158	11	antigen	antigen	NN
cord-285778-80baxwgc	158	12	is	be	VBZ
cord-285778-80baxwgc	158	13	determined	determine	VBN
cord-285778-80baxwgc	158	14	by	by	IN
cord-285778-80baxwgc	158	15	the	the	DT
cord-285778-80baxwgc	158	16	nature	nature	NN
cord-285778-80baxwgc	158	17	of	of	IN
cord-285778-80baxwgc	158	18	the	the	DT
cord-285778-80baxwgc	158	19	antigen	antigen	NN
cord-285778-80baxwgc	158	20	receptors	receptor	NNS
cord-285778-80baxwgc	158	21	expressed	express	VBN
cord-285778-80baxwgc	158	22	on	on	IN
cord-285778-80baxwgc	158	23	the	the	DT
cord-285778-80baxwgc	158	24	surfaces	surface	NNS
cord-285778-80baxwgc	158	25	of	of	IN
cord-285778-80baxwgc	158	26	T	t	NN
cord-285778-80baxwgc	158	27	and	and	CC
cord-285778-80baxwgc	158	28	B	b	NN
cord-285778-80baxwgc	158	29	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	158	30	.	.	.
cord-285778-80baxwgc	159	1	Each	each	DT
cord-285778-80baxwgc	159	2	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	159	3	expresses	express	VBZ
cord-285778-80baxwgc	159	4	thousands	thousand	NNS
cord-285778-80baxwgc	159	5	of	of	IN
cord-285778-80baxwgc	159	6	identical	identical	JJ
cord-285778-80baxwgc	159	7	copies	copy	NNS
cord-285778-80baxwgc	159	8	of	of	IN
cord-285778-80baxwgc	159	9	a	a	DT
cord-285778-80baxwgc	159	10	unique	unique	JJ
cord-285778-80baxwgc	159	11	antigen	antigen	NN
cord-285778-80baxwgc	159	12	receptor	receptor	NN
cord-285778-80baxwgc	159	13	protein	protein	NN
cord-285778-80baxwgc	159	14	.	.	.
cord-285778-80baxwgc	160	1	Interaction	interaction	NN
cord-285778-80baxwgc	160	2	of	of	IN
cord-285778-80baxwgc	160	3	these	these	DT
cord-285778-80baxwgc	160	4	antigen	antigen	NN
cord-285778-80baxwgc	160	5	receptor	receptor	NN
cord-285778-80baxwgc	160	6	molecules	molecule	NNS
cord-285778-80baxwgc	160	7	with	with	IN
cord-285778-80baxwgc	160	8	antigen	antigen	NN
cord-285778-80baxwgc	160	9	triggers	trigger	VBZ
cord-285778-80baxwgc	160	10	activation	activation	NN
cord-285778-80baxwgc	160	11	of	of	IN
cord-285778-80baxwgc	160	12	the	the	DT
cord-285778-80baxwgc	160	13	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	160	14	.	.	.
cord-285778-80baxwgc	161	1	In	in	IN
cord-285778-80baxwgc	161	2	contrast	contrast	NN
cord-285778-80baxwgc	161	3	to	to	IN
cord-285778-80baxwgc	161	4	the	the	DT
cord-285778-80baxwgc	161	5	broad	broad	JJ
cord-285778-80baxwgc	161	6	recognition	recognition	NN
cord-285778-80baxwgc	161	7	mediated	mediate	VBN
cord-285778-80baxwgc	161	8	by	by	IN
cord-285778-80baxwgc	161	9	PRMs	prm	NNS
cord-285778-80baxwgc	161	10	,	,	,
cord-285778-80baxwgc	161	11	antigen	antigen	NN
cord-285778-80baxwgc	161	12	binding	bind	VBG
cord-285778-80baxwgc	161	13	to	to	IN
cord-285778-80baxwgc	161	14	a	a	DT
cord-285778-80baxwgc	161	15	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	161	16	antigen	antigen	NN
cord-285778-80baxwgc	161	17	receptor	receptor	NN
cord-285778-80baxwgc	161	18	usually	usually	RB
cord-285778-80baxwgc	161	19	hinges	hinge	VBZ
cord-285778-80baxwgc	161	20	on	on	IN
cord-285778-80baxwgc	161	21	the	the	DT
cord-285778-80baxwgc	161	22	presence	presence	NN
cord-285778-80baxwgc	161	23	of	of	IN
cord-285778-80baxwgc	161	24	a	a	DT
cord-285778-80baxwgc	161	25	unique	unique	JJ
cord-285778-80baxwgc	161	26	molecular	molecular	JJ
cord-285778-80baxwgc	161	27	shape	shape	NN
cord-285778-80baxwgc	161	28	unlikely	unlikely	JJ
cord-285778-80baxwgc	161	29	to	to	TO
cord-285778-80baxwgc	161	30	appear	appear	VB
cord-285778-80baxwgc	161	31	on	on	IN
cord-285778-80baxwgc	161	32	more	more	JJR
cord-285778-80baxwgc	161	33	than	than	IN
cord-285778-80baxwgc	161	34	one	one	CD
cord-285778-80baxwgc	161	35	pathogen	pathogen	NN
cord-285778-80baxwgc	161	36	.	.	.
cord-285778-80baxwgc	162	1	The	the	DT
cord-285778-80baxwgc	162	2	antigen	antigen	NN
cord-285778-80baxwgc	162	3	receptors	receptor	NNS
cord-285778-80baxwgc	162	4	on	on	IN
cord-285778-80baxwgc	162	5	the	the	DT
cord-285778-80baxwgc	162	6	surface	surface	NN
cord-285778-80baxwgc	162	7	of	of	IN
cord-285778-80baxwgc	162	8	a	a	DT
cord-285778-80baxwgc	162	9	B	b	NN
cord-285778-80baxwgc	162	10	cell	cell	NN
cord-285778-80baxwgc	162	11	are	be	VBP
cord-285778-80baxwgc	162	12	called	call	VBN
cord-285778-80baxwgc	162	13	B	b	NN
cord-285778-80baxwgc	162	14	cell	cell	NN
cord-285778-80baxwgc	162	15	receptors	receptor	NNS
cord-285778-80baxwgc	162	16	(	(	-LRB-
cord-285778-80baxwgc	162	17	BCRs	BCRs	NNP
cord-285778-80baxwgc	162	18	)	)	-RRB-
cord-285778-80baxwgc	162	19	,	,	,
cord-285778-80baxwgc	162	20	whereas	whereas	IN
cord-285778-80baxwgc	162	21	those	those	DT
cord-285778-80baxwgc	162	22	on	on	IN
cord-285778-80baxwgc	162	23	the	the	DT
cord-285778-80baxwgc	162	24	T	T	NNP
cord-285778-80baxwgc	162	25	cell	cell	NN
cord-285778-80baxwgc	162	26	surface	surface	NN
cord-285778-80baxwgc	162	27	are	be	VBP
cord-285778-80baxwgc	162	28	called	call	VBN
cord-285778-80baxwgc	162	29	T	T	NNP
cord-285778-80baxwgc	162	30	cell	cell	NN
cord-285778-80baxwgc	162	31	receptors	receptor	NNS
cord-285778-80baxwgc	162	32	(	(	-LRB-
cord-285778-80baxwgc	162	33	TCRs	TCRs	NNP
cord-285778-80baxwgc	162	34	)	)	-RRB-
cord-285778-80baxwgc	162	35	.	.	.
cord-285778-80baxwgc	163	1	In	in	IN
cord-285778-80baxwgc	163	2	both	both	DT
cord-285778-80baxwgc	163	3	cases	case	NNS
cord-285778-80baxwgc	163	4	,	,	,
cord-285778-80baxwgc	163	5	the	the	DT
cord-285778-80baxwgc	163	6	antigen	antigen	NN
cord-285778-80baxwgc	163	7	receptor	receptor	NN
cord-285778-80baxwgc	163	8	is	be	VBZ
cord-285778-80baxwgc	163	9	itself	-PRON-	PRP
cord-285778-80baxwgc	163	10	a	a	DT
cord-285778-80baxwgc	163	11	complex	complex	NN
cord-285778-80baxwgc	163	12	of	of	IN
cord-285778-80baxwgc	163	13	several	several	JJ
cord-285778-80baxwgc	163	14	proteins	protein	NNS
cord-285778-80baxwgc	163	15	.	.	.
cord-285778-80baxwgc	164	1	Some	some	DT
cord-285778-80baxwgc	164	2	of	of	IN
cord-285778-80baxwgc	164	3	these	these	DT
cord-285778-80baxwgc	164	4	proteins	protein	NNS
cord-285778-80baxwgc	164	5	interact	interact	VBP
cord-285778-80baxwgc	164	6	directly	directly	RB
cord-285778-80baxwgc	164	7	and	and	CC
cord-285778-80baxwgc	164	8	specifically	specifically	RB
cord-285778-80baxwgc	164	9	with	with	IN
cord-285778-80baxwgc	164	10	antigen	antigen	NN
cord-285778-80baxwgc	164	11	,	,	,
cord-285778-80baxwgc	164	12	while	while	IN
cord-285778-80baxwgc	164	13	others	other	NNS
cord-285778-80baxwgc	164	14	convey	convey	VBP
cord-285778-80baxwgc	164	15	the	the	DT
cord-285778-80baxwgc	164	16	intracellular	intracellular	JJ
cord-285778-80baxwgc	164	17	signals	signal	NNS
cord-285778-80baxwgc	164	18	triggered	trigger	VBN
cord-285778-80baxwgc	164	19	by	by	IN
cord-285778-80baxwgc	164	20	antigen	antigen	NN
cord-285778-80baxwgc	164	21	binding	bind	VBG
cord-285778-80baxwgc	164	22	into	into	IN
cord-285778-80baxwgc	164	23	the	the	DT
cord-285778-80baxwgc	164	24	cytoplasm	cytoplasm	NN
cord-285778-80baxwgc	164	25	and	and	CC
cord-285778-80baxwgc	164	26	nucleus	nucleus	NN
cord-285778-80baxwgc	164	27	of	of	IN
cord-285778-80baxwgc	164	28	the	the	DT
cord-285778-80baxwgc	164	29	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	164	30	.	.	.
cord-285778-80baxwgc	165	1	These	these	DT
cord-285778-80baxwgc	165	2	signals	signal	NNS
cord-285778-80baxwgc	165	3	are	be	VBP
cord-285778-80baxwgc	165	4	critical	critical	JJ
cord-285778-80baxwgc	165	5	for	for	IN
cord-285778-80baxwgc	165	6	sustaining	sustain	VBG
cord-285778-80baxwgc	165	7	the	the	DT
cord-285778-80baxwgc	165	8	activation	activation	NN
cord-285778-80baxwgc	165	9	of	of	IN
cord-285778-80baxwgc	165	10	the	the	DT
cord-285778-80baxwgc	165	11	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	165	12	and	and	CC
cord-285778-80baxwgc	165	13	promoting	promote	VBG
cord-285778-80baxwgc	165	14	its	-PRON-	PRP$
cord-285778-80baxwgc	165	15	proliferation	proliferation	NN
cord-285778-80baxwgc	165	16	into	into	IN
cord-285778-80baxwgc	165	17	an	an	DT
cord-285778-80baxwgc	165	18	army	army	NN
cord-285778-80baxwgc	165	19	of	of	IN
cord-285778-80baxwgc	165	20	short	short	RB
cord-285778-80baxwgc	165	21	-	-	HYPH
cord-285778-80baxwgc	165	22	lived	live	VBN
cord-285778-80baxwgc	165	23	daughter	daughter	NN
cord-285778-80baxwgc	165	24	effector	effector	NN
cord-285778-80baxwgc	165	25	cells	cell	NNS
cord-285778-80baxwgc	165	26	.	.	.
cord-285778-80baxwgc	166	1	These	these	DT
cord-285778-80baxwgc	166	2	effector	effector	NN
cord-285778-80baxwgc	166	3	cells	cell	NNS
cord-285778-80baxwgc	166	4	then	then	RB
cord-285778-80baxwgc	166	5	undertake	undertake	VBP
cord-285778-80baxwgc	166	6	the	the	DT
cord-285778-80baxwgc	166	7	effector	effector	JJ
cord-285778-80baxwgc	166	8	action	action	NN
cord-285778-80baxwgc	166	9	appropriate	appropriate	JJ
cord-285778-80baxwgc	166	10	for	for	IN
cord-285778-80baxwgc	166	11	eliminating	eliminate	VBG
cord-285778-80baxwgc	166	12	the	the	DT
cord-285778-80baxwgc	166	13	pathogen	pathogen	NN
cord-285778-80baxwgc	166	14	furnishing	furnish	VBG
cord-285778-80baxwgc	166	15	the	the	DT
cord-285778-80baxwgc	166	16	antigen	antigen	NN
cord-285778-80baxwgc	166	17	.	.	.
cord-285778-80baxwgc	167	1	"	"	``
cord-285778-80baxwgc	167	2	Division	Division	NNP
cord-285778-80baxwgc	167	3	of	of	IN
cord-285778-80baxwgc	167	4	labor	labor	NN
cord-285778-80baxwgc	167	5	"	"	''
cord-285778-80baxwgc	167	6	in	in	IN
cord-285778-80baxwgc	167	7	the	the	DT
cord-285778-80baxwgc	167	8	adaptive	adaptive	JJ
cord-285778-80baxwgc	167	9	response	response	NN
cord-285778-80baxwgc	167	10	refers	refer	VBZ
cord-285778-80baxwgc	167	11	to	to	IN
cord-285778-80baxwgc	167	12	the	the	DT
cord-285778-80baxwgc	167	13	different	different	JJ
cord-285778-80baxwgc	167	14	but	but	CC
cord-285778-80baxwgc	167	15	equally	equally	RB
cord-285778-80baxwgc	167	16	important	important	JJ
cord-285778-80baxwgc	167	17	contributions	contribution	NNS
cord-285778-80baxwgc	167	18	of	of	IN
cord-285778-80baxwgc	167	19	B	b	NN
cord-285778-80baxwgc	167	20	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	167	21	and	and	CC
cord-285778-80baxwgc	167	22	two	two	CD
cord-285778-80baxwgc	167	23	types	type	NNS
cord-285778-80baxwgc	167	24	of	of	IN
cord-285778-80baxwgc	167	25	T	t	NN
cord-285778-80baxwgc	167	26	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	167	27	.	.	.
cord-285778-80baxwgc	168	1	These	these	DT
cord-285778-80baxwgc	168	2	two	two	CD
cord-285778-80baxwgc	168	3	major	major	JJ
cord-285778-80baxwgc	168	4	T	t	NN
cord-285778-80baxwgc	168	5	cell	cell	NN
cord-285778-80baxwgc	168	6	subsets	subset	NNS
cord-285778-80baxwgc	168	7	are	be	VBP
cord-285778-80baxwgc	168	8	called	call	VBN
cord-285778-80baxwgc	168	9	cytotoxic	cytotoxic	JJ
cord-285778-80baxwgc	168	10	T	t	NN
cord-285778-80baxwgc	168	11	cells	cell	NNS
cord-285778-80baxwgc	168	12	(	(	-LRB-
cord-285778-80baxwgc	168	13	Tc	Tc	NNP
cord-285778-80baxwgc	168	14	)	)	-RRB-
cord-285778-80baxwgc	168	15	and	and	CC
cord-285778-80baxwgc	168	16	helper	helper	NN
cord-285778-80baxwgc	168	17	T	t	NN
cord-285778-80baxwgc	168	18	cells	cell	NNS
cord-285778-80baxwgc	168	19	(	(	-LRB-
cord-285778-80baxwgc	168	20	Th	Th	NNP
cord-285778-80baxwgc	168	21	)	)	-RRB-
cord-285778-80baxwgc	168	22	.	.	.
cord-285778-80baxwgc	169	1	The	the	DT
cord-285778-80baxwgc	169	2	roles	role	NNS
cord-285778-80baxwgc	169	3	of	of	IN
cord-285778-80baxwgc	169	4	B	b	NN
cord-285778-80baxwgc	169	5	,	,	,
cord-285778-80baxwgc	169	6	Tc	Tc	NNP
cord-285778-80baxwgc	169	7	and	and	CC
cord-285778-80baxwgc	169	8	Th	Th	NNP
cord-285778-80baxwgc	169	9	cells	cell	NNS
cord-285778-80baxwgc	169	10	in	in	IN
cord-285778-80baxwgc	169	11	the	the	DT
cord-285778-80baxwgc	169	12	adaptive	adaptive	JJ
cord-285778-80baxwgc	169	13	response	response	NN
cord-285778-80baxwgc	169	14	are	be	VBP
cord-285778-80baxwgc	169	15	defined	define	VBN
cord-285778-80baxwgc	169	16	by	by	IN
cord-285778-80baxwgc	169	17	the	the	DT
cord-285778-80baxwgc	169	18	distinct	distinct	JJ
cord-285778-80baxwgc	169	19	mechanisms	mechanism	NNS
cord-285778-80baxwgc	169	20	by	by	IN
cord-285778-80baxwgc	169	21	which	which	WDT
cord-285778-80baxwgc	169	22	they	-PRON-	PRP
cord-285778-80baxwgc	169	23	recognize	recognize	VBP
cord-285778-80baxwgc	169	24	and	and	CC
cord-285778-80baxwgc	169	25	respond	respond	VBP
cord-285778-80baxwgc	169	26	to	to	IN
cord-285778-80baxwgc	169	27	antigen	antigen	NNP
cord-285778-80baxwgc	169	28	(	(	-LRB-
cord-285778-80baxwgc	169	29	Table	table	NN
cord-285778-80baxwgc	169	30	1	1	CD
cord-285778-80baxwgc	169	31	-	-	SYM
cord-285778-80baxwgc	169	32	2	2	CD
cord-285778-80baxwgc	169	33	)	)	-RRB-
cord-285778-80baxwgc	169	34	.	.	.
cord-285778-80baxwgc	170	1	B	b	NN
cord-285778-80baxwgc	170	2	cells	cell	NNS
cord-285778-80baxwgc	170	3	recognize	recognize	VBP
cord-285778-80baxwgc	170	4	antigen	antigen	NN
cord-285778-80baxwgc	170	5	in	in	IN
cord-285778-80baxwgc	170	6	a	a	DT
cord-285778-80baxwgc	170	7	way	way	NN
cord-285778-80baxwgc	170	8	that	that	WDT
cord-285778-80baxwgc	170	9	is	be	VBZ
cord-285778-80baxwgc	170	10	fundamentally	fundamentally	RB
cord-285778-80baxwgc	170	11	different	different	JJ
cord-285778-80baxwgc	170	12	from	from	IN
cord-285778-80baxwgc	170	13	that	that	DT
cord-285778-80baxwgc	170	14	used	use	VBN
cord-285778-80baxwgc	170	15	by	by	IN
cord-285778-80baxwgc	170	16	Tc	Tc	NNP
cord-285778-80baxwgc	170	17	and	and	CC
cord-285778-80baxwgc	170	18	Th	Th	NNP
cord-285778-80baxwgc	170	19	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	170	20	.	.	.
cord-285778-80baxwgc	171	1	The	the	DT
cord-285778-80baxwgc	171	2	BCR	BCR	NNP
cord-285778-80baxwgc	171	3	of	of	IN
cord-285778-80baxwgc	171	4	a	a	DT
cord-285778-80baxwgc	171	5	B	b	NN
cord-285778-80baxwgc	171	6	cell	cell	NN
cord-285778-80baxwgc	171	7	binds	bind	VBZ
cord-285778-80baxwgc	171	8	directly	directly	RB
cord-285778-80baxwgc	171	9	to	to	IN
cord-285778-80baxwgc	171	10	an	an	DT
cord-285778-80baxwgc	171	11	intact	intact	JJ
cord-285778-80baxwgc	171	12	antigen	antigen	NN
cord-285778-80baxwgc	171	13	,	,	,
cord-285778-80baxwgc	171	14	which	which	WDT
cord-285778-80baxwgc	171	15	may	may	MD
cord-285778-80baxwgc	171	16	be	be	VB
cord-285778-80baxwgc	171	17	either	either	CC
cord-285778-80baxwgc	171	18	a	a	DT
cord-285778-80baxwgc	171	19	soluble	soluble	JJ
cord-285778-80baxwgc	171	20	molecule	molecule	NN
cord-285778-80baxwgc	171	21	or	or	CC
cord-285778-80baxwgc	171	22	a	a	DT
cord-285778-80baxwgc	171	23	molecule	molecule	NN
cord-285778-80baxwgc	171	24	present	present	JJ
cord-285778-80baxwgc	171	25	on	on	IN
cord-285778-80baxwgc	171	26	the	the	DT
cord-285778-80baxwgc	171	27	surface	surface	NN
cord-285778-80baxwgc	171	28	of	of	IN
cord-285778-80baxwgc	171	29	a	a	DT
cord-285778-80baxwgc	171	30	pathogen	pathogen	NN
cord-285778-80baxwgc	171	31	(	(	-LRB-
cord-285778-80baxwgc	171	32	Fig	Fig	NNP
cord-285778-80baxwgc	171	33	.	.	NNP
cord-285778-80baxwgc	171	34	1	1	CD
cord-285778-80baxwgc	171	35	-	-	HYPH
cord-285778-80baxwgc	171	36	5A	5a	CD
cord-285778-80baxwgc	171	37	)	)	-RRB-
cord-285778-80baxwgc	171	38	.	.	.
cord-285778-80baxwgc	172	1	Activation	activation	NN
cord-285778-80baxwgc	172	2	of	of	IN
cord-285778-80baxwgc	172	3	a	a	DT
cord-285778-80baxwgc	172	4	B	b	NN
cord-285778-80baxwgc	172	5	cell	cell	NN
cord-285778-80baxwgc	172	6	in	in	IN
cord-285778-80baxwgc	172	7	this	this	DT
cord-285778-80baxwgc	172	8	way	way	NN
cord-285778-80baxwgc	172	9	causes	cause	VBZ
cord-285778-80baxwgc	172	10	it	-PRON-	PRP
cord-285778-80baxwgc	172	11	to	to	TO
cord-285778-80baxwgc	172	12	proliferate	proliferate	VB
cord-285778-80baxwgc	172	13	and	and	CC
cord-285778-80baxwgc	172	14	produce	produce	VB
cord-285778-80baxwgc	172	15	identical	identical	JJ
cord-285778-80baxwgc	172	16	daughter	daughter	NN
cord-285778-80baxwgc	172	17	effector	effector	NN
cord-285778-80baxwgc	172	18	cells	cell	NNS
cord-285778-80baxwgc	172	19	called	call	VBD
cord-285778-80baxwgc	172	20	plasma	plasma	NN
cord-285778-80baxwgc	172	21	cells	cell	NNS
cord-285778-80baxwgc	172	22	that	that	WDT
cord-285778-80baxwgc	172	23	secrete	secrete	VBP
cord-285778-80baxwgc	172	24	vast	vast	JJ
cord-285778-80baxwgc	172	25	quantities	quantity	NNS
cord-285778-80baxwgc	172	26	of	of	IN
cord-285778-80baxwgc	172	27	specific	specific	JJ
cord-285778-80baxwgc	172	28	antibody	antibody	NN
cord-285778-80baxwgc	172	29	.	.	.
cord-285778-80baxwgc	173	1	An	an	DT
cord-285778-80baxwgc	173	2	antibody	antibody	NN
cord-285778-80baxwgc	173	3	is	be	VBZ
cord-285778-80baxwgc	173	4	a	a	DT
cord-285778-80baxwgc	173	5	protein	protein	NN
cord-285778-80baxwgc	173	6	that	that	WDT
cord-285778-80baxwgc	173	7	is	be	VBZ
cord-285778-80baxwgc	173	8	a	a	DT
cord-285778-80baxwgc	173	9	modified	modified	JJ
cord-285778-80baxwgc	173	10	,	,	,
cord-285778-80baxwgc	173	11	soluble	soluble	JJ
cord-285778-80baxwgc	173	12	form	form	NN
cord-285778-80baxwgc	173	13	of	of	IN
cord-285778-80baxwgc	173	14	the	the	DT
cord-285778-80baxwgc	173	15	original	original	JJ
cord-285778-80baxwgc	173	16	B	B	NNP
cord-285778-80baxwgc	173	17	cell	cell	NN
cord-285778-80baxwgc	173	18	's	's	POS
cord-285778-80baxwgc	173	19	membrane	membrane	NN
cord-285778-80baxwgc	173	20	-	-	HYPH
cord-285778-80baxwgc	173	21	bound	bind	VBN
cord-285778-80baxwgc	173	22	antigen	antigen	NN
cord-285778-80baxwgc	173	23	receptor	receptor	NN
cord-285778-80baxwgc	173	24	.	.	.
cord-285778-80baxwgc	174	1	Antibody	antibody	NN
cord-285778-80baxwgc	174	2	molecules	molecule	NNS
cord-285778-80baxwgc	174	3	enter	enter	VBP
cord-285778-80baxwgc	174	4	the	the	DT
cord-285778-80baxwgc	174	5	host	host	NN
cord-285778-80baxwgc	174	6	's	's	POS
cord-285778-80baxwgc	174	7	circulation	circulation	NN
cord-285778-80baxwgc	174	8	and	and	CC
cord-285778-80baxwgc	174	9	tissues	tissue	NNS
cord-285778-80baxwgc	174	10	,	,	,
cord-285778-80baxwgc	174	11	bind	bind	VB
cord-285778-80baxwgc	174	12	to	to	IN
cord-285778-80baxwgc	174	13	the	the	DT
cord-285778-80baxwgc	174	14	specific	specific	JJ
cord-285778-80baxwgc	174	15	antigen	antigen	NN
cord-285778-80baxwgc	174	16	,	,	,
cord-285778-80baxwgc	174	17	and	and	CC
cord-285778-80baxwgc	174	18	mark	mark	VB
cord-285778-80baxwgc	174	19	it	-PRON-	PRP
cord-285778-80baxwgc	174	20	for	for	IN
cord-285778-80baxwgc	174	21	clearance	clearance	NN
cord-285778-80baxwgc	174	22	from	from	IN
cord-285778-80baxwgc	174	23	the	the	DT
cord-285778-80baxwgc	174	24	body	body	NN
cord-285778-80baxwgc	174	25	,	,	,
cord-285778-80baxwgc	174	26	establishing	establish	VBG
cord-285778-80baxwgc	174	27	a	a	DT
cord-285778-80baxwgc	174	28	humoral	humoral	JJ
cord-285778-80baxwgc	174	29	response	response	NN
cord-285778-80baxwgc	174	30	.	.	.
cord-285778-80baxwgc	175	1	Since	since	IN
cord-285778-80baxwgc	175	2	antibodies	antibody	NNS
cord-285778-80baxwgc	175	3	are	be	VBP
cord-285778-80baxwgc	175	4	present	present	JJ
cord-285778-80baxwgc	175	5	in	in	IN
cord-285778-80baxwgc	175	6	the	the	DT
cord-285778-80baxwgc	175	7	extracellular	extracellular	JJ
cord-285778-80baxwgc	175	8	milieu	milieu	NN
cord-285778-80baxwgc	175	9	,	,	,
cord-285778-80baxwgc	175	10	such	such	PDT
cord-285778-80baxwgc	175	11	a	a	DT
cord-285778-80baxwgc	175	12	response	response	NN
cord-285778-80baxwgc	175	13	is	be	VBZ
cord-285778-80baxwgc	175	14	effective	effective	JJ
cord-285778-80baxwgc	175	15	against	against	IN
cord-285778-80baxwgc	175	16	extracellular	extracellular	JJ
cord-285778-80baxwgc	175	17	pathogens	pathogen	NNS
cord-285778-80baxwgc	175	18	.	.	.
cord-285778-80baxwgc	176	1	However	however	RB
cord-285778-80baxwgc	176	2	,	,	,
cord-285778-80baxwgc	176	3	antibodies	antibody	NNS
cord-285778-80baxwgc	176	4	are	be	VBP
cord-285778-80baxwgc	176	5	unable	unable	JJ
cord-285778-80baxwgc	176	6	to	to	TO
cord-285778-80baxwgc	176	7	penetrate	penetrate	VB
cord-285778-80baxwgc	176	8	cell	cell	NN
cord-285778-80baxwgc	176	9	membranes	membrane	NNS
cord-285778-80baxwgc	176	10	and	and	CC
cord-285778-80baxwgc	176	11	so	so	RB
cord-285778-80baxwgc	176	12	can	can	MD
cord-285778-80baxwgc	176	13	not	not	RB
cord-285778-80baxwgc	176	14	attack	attack	VB
cord-285778-80baxwgc	176	15	an	an	DT
cord-285778-80baxwgc	176	16	intracellular	intracellular	JJ
cord-285778-80baxwgc	176	17	pathogen	pathogen	NN
cord-285778-80baxwgc	176	18	once	once	IN
cord-285778-80baxwgc	176	19	it	-PRON-	PRP
cord-285778-80baxwgc	176	20	has	have	VBZ
cord-285778-80baxwgc	176	21	entered	enter	VBN
cord-285778-80baxwgc	176	22	a	a	DT
cord-285778-80baxwgc	176	23	host	host	NN
cord-285778-80baxwgc	176	24	cell	cell	NN
cord-285778-80baxwgc	176	25	.	.	.
cord-285778-80baxwgc	177	1	Unlike	unlike	IN
cord-285778-80baxwgc	177	2	BCRs	bcr	NNS
cord-285778-80baxwgc	177	3	,	,	,
cord-285778-80baxwgc	177	4	TCRs	tcr	NNS
cord-285778-80baxwgc	177	5	are	be	VBP
cord-285778-80baxwgc	177	6	unable	unable	JJ
cord-285778-80baxwgc	177	7	to	to	TO
cord-285778-80baxwgc	177	8	recognize	recognize	VB
cord-285778-80baxwgc	177	9	whole	whole	JJ
cord-285778-80baxwgc	177	10	,	,	,
cord-285778-80baxwgc	177	11	native	native	JJ
cord-285778-80baxwgc	177	12	antigens	antigen	NNS
cord-285778-80baxwgc	177	13	.	.	.
cord-285778-80baxwgc	178	1	Rather	rather	RB
cord-285778-80baxwgc	178	2	,	,	,
cord-285778-80baxwgc	178	3	a	a	DT
cord-285778-80baxwgc	178	4	TCR	TCR	NNP
cord-285778-80baxwgc	178	5	recognizes	recognize	VBZ
cord-285778-80baxwgc	178	6	a	a	DT
cord-285778-80baxwgc	178	7	bipartite	bipartite	JJ
cord-285778-80baxwgc	178	8	structure	structure	NN
cord-285778-80baxwgc	178	9	displayed	display	VBN
cord-285778-80baxwgc	178	10	on	on	IN
cord-285778-80baxwgc	178	11	the	the	DT
cord-285778-80baxwgc	178	12	surface	surface	NN
cord-285778-80baxwgc	178	13	of	of	IN
cord-285778-80baxwgc	178	14	a	a	DT
cord-285778-80baxwgc	178	15	host	host	NN
cord-285778-80baxwgc	178	16	cell	cell	NN
cord-285778-80baxwgc	178	17	.	.	.
cord-285778-80baxwgc	179	1	This	this	DT
cord-285778-80baxwgc	179	2	bipartite	bipartite	JJ
cord-285778-80baxwgc	179	3	structure	structure	NN
cord-285778-80baxwgc	179	4	is	be	VBZ
cord-285778-80baxwgc	179	5	made	make	VBN
cord-285778-80baxwgc	179	6	up	up	RP
cord-285778-80baxwgc	179	7	of	of	IN
cord-285778-80baxwgc	179	8	a	a	DT
cord-285778-80baxwgc	179	9	host	host	NN
cord-285778-80baxwgc	179	10	surface	surface	NN
cord-285778-80baxwgc	179	11	protein	protein	NN
cord-285778-80baxwgc	179	12	called	call	VBD
cord-285778-80baxwgc	179	13	an	an	DT
cord-285778-80baxwgc	179	14	MHC	MHC	NNP
cord-285778-80baxwgc	179	15	molecule	molecule	NN
cord-285778-80baxwgc	179	16	bound	bind	VBN
cord-285778-80baxwgc	179	17	to	to	IN
cord-285778-80baxwgc	179	18	a	a	DT
cord-285778-80baxwgc	179	19	short	short	JJ
cord-285778-80baxwgc	179	20	peptide	peptide	NN
cord-285778-80baxwgc	179	21	derived	derive	VBN
cord-285778-80baxwgc	179	22	from	from	IN
cord-285778-80baxwgc	179	23	a	a	DT
cord-285778-80baxwgc	179	24	protein	protein	NN
cord-285778-80baxwgc	179	25	antigen	antigen	NN
cord-285778-80baxwgc	179	26	.	.	.
cord-285778-80baxwgc	180	1	This	this	DT
cord-285778-80baxwgc	180	2	complex	complex	NN
cord-285778-80baxwgc	180	3	is	be	VBZ
cord-285778-80baxwgc	180	4	referred	refer	VBN
cord-285778-80baxwgc	180	5	to	to	IN
cord-285778-80baxwgc	180	6	as	as	IN
cord-285778-80baxwgc	180	7	a	a	DT
cord-285778-80baxwgc	180	8	peptide	peptide	NN
cord-285778-80baxwgc	180	9	-	-	HYPH
cord-285778-80baxwgc	180	10	MHC	MHC	NNP
cord-285778-80baxwgc	180	11	complex	complex	NN
cord-285778-80baxwgc	180	12	(	(	-LRB-
cord-285778-80baxwgc	180	13	pMHC	pmhc	NN
cord-285778-80baxwgc	180	14	)	)	-RRB-
cord-285778-80baxwgc	180	15	.	.	.
cord-285778-80baxwgc	181	1	Tc	Tc	NNP
cord-285778-80baxwgc	181	2	and	and	CC
cord-285778-80baxwgc	181	3	Th	Th	NNP
cord-285778-80baxwgc	181	4	cells	cell	NNS
cord-285778-80baxwgc	181	5	are	be	VBP
cord-285778-80baxwgc	181	6	activated	activate	VBN
cord-285778-80baxwgc	181	7	by	by	IN
cord-285778-80baxwgc	181	8	the	the	DT
cord-285778-80baxwgc	181	9	binding	binding	NN
cord-285778-80baxwgc	181	10	of	of	IN
cord-285778-80baxwgc	181	11	their	-PRON-	PRP$
cord-285778-80baxwgc	181	12	TCRs	tcr	NNS
cord-285778-80baxwgc	181	13	to	to	IN
cord-285778-80baxwgc	181	14	specific	specific	JJ
cord-285778-80baxwgc	181	15	pMHCs	pmhc	NNS
cord-285778-80baxwgc	181	16	presented	present	VBN
cord-285778-80baxwgc	181	17	on	on	IN
cord-285778-80baxwgc	181	18	the	the	DT
cord-285778-80baxwgc	181	19	surface	surface	NN
cord-285778-80baxwgc	181	20	of	of	IN
cord-285778-80baxwgc	181	21	a	a	DT
cord-285778-80baxwgc	181	22	DC	DC	NNP
cord-285778-80baxwgc	181	23	.	.	.
cord-285778-80baxwgc	182	1	DCs	DCs	NNP
cord-285778-80baxwgc	182	2	can	can	MD
cord-285778-80baxwgc	182	3	acquire	acquire	VB
cord-285778-80baxwgc	182	4	extracellular	extracellular	JJ
cord-285778-80baxwgc	182	5	pathogen	pathogen	NN
cord-285778-80baxwgc	182	6	antigens	antigen	NNS
cord-285778-80baxwgc	182	7	by	by	IN
cord-285778-80baxwgc	182	8	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	182	9	,	,	,
cord-285778-80baxwgc	182	10	and	and	CC
cord-285778-80baxwgc	182	11	intracellular	intracellular	JJ
cord-285778-80baxwgc	182	12	pathogen	pathogen	NN
cord-285778-80baxwgc	182	13	antigens	antigen	NNS
cord-285778-80baxwgc	182	14	either	either	CC
cord-285778-80baxwgc	182	15	by	by	IN
cord-285778-80baxwgc	182	16	infection	infection	NN
cord-285778-80baxwgc	182	17	or	or	CC
cord-285778-80baxwgc	182	18	by	by	IN
cord-285778-80baxwgc	182	19	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	182	20	of	of	IN
cord-285778-80baxwgc	182	21	the	the	DT
cord-285778-80baxwgc	182	22	debris	debris	NN
cord-285778-80baxwgc	182	23	of	of	IN
cord-285778-80baxwgc	182	24	dead	dead	JJ
cord-285778-80baxwgc	182	25	infected	infected	JJ
cord-285778-80baxwgc	182	26	cells	cell	NNS
cord-285778-80baxwgc	182	27	.	.	.
cord-285778-80baxwgc	183	1	Peptides	peptide	NNS
cord-285778-80baxwgc	183	2	from	from	IN
cord-285778-80baxwgc	183	3	these	these	DT
cord-285778-80baxwgc	183	4	antigens	antigen	NNS
cord-285778-80baxwgc	183	5	are	be	VBP
cord-285778-80baxwgc	183	6	bound	bind	VBN
cord-285778-80baxwgc	183	7	to	to	IN
cord-285778-80baxwgc	183	8	one	one	CD
cord-285778-80baxwgc	183	9	of	of	IN
cord-285778-80baxwgc	183	10	two	two	CD
cord-285778-80baxwgc	183	11	types	type	NNS
cord-285778-80baxwgc	183	12	of	of	IN
cord-285778-80baxwgc	183	13	MHC	MHC	NNP
cord-285778-80baxwgc	183	14	molecules	molecule	NNS
cord-285778-80baxwgc	183	15	,	,	,
cord-285778-80baxwgc	183	16	either	either	CC
cord-285778-80baxwgc	183	17	MHC	MHC	NNP
cord-285778-80baxwgc	183	18	class	class	NN
cord-285778-80baxwgc	183	19	I	I	NNP
cord-285778-80baxwgc	183	20	or	or	CC
cord-285778-80baxwgc	183	21	MHC	MHC	NNP
cord-285778-80baxwgc	183	22	class	class	NN
cord-285778-80baxwgc	183	23	II	II	NNP
cord-285778-80baxwgc	183	24	,	,	,
cord-285778-80baxwgc	183	25	and	and	CC
cord-285778-80baxwgc	183	26	then	then	RB
cord-285778-80baxwgc	183	27	displayed	display	VBD
cord-285778-80baxwgc	183	28	on	on	IN
cord-285778-80baxwgc	183	29	the	the	DT
cord-285778-80baxwgc	183	30	DC	DC	NNP
cord-285778-80baxwgc	183	31	surface	surface	NN
cord-285778-80baxwgc	183	32	for	for	IN
cord-285778-80baxwgc	183	33	inspection	inspection	NN
cord-285778-80baxwgc	183	34	by	by	IN
cord-285778-80baxwgc	183	35	T	T	NNP
cord-285778-80baxwgc	183	36	cells	cell	NNS
cord-285778-80baxwgc	183	37	.	.	.
cord-285778-80baxwgc	184	1	Tc	Tc	NNP
cord-285778-80baxwgc	184	2	cells	cell	NNS
cord-285778-80baxwgc	184	3	recognize	recognize	VBP
cord-285778-80baxwgc	184	4	antigenic	antigenic	JJ
cord-285778-80baxwgc	184	5	peptides	peptide	NNS
cord-285778-80baxwgc	184	6	that	that	IN
cord-285778-80baxwgc	184	7	the	the	DT
cord-285778-80baxwgc	184	8	DC	DC	NNP
cord-285778-80baxwgc	184	9	has	have	VBZ
cord-285778-80baxwgc	184	10	presented	present	VBN
cord-285778-80baxwgc	184	11	on	on	IN
cord-285778-80baxwgc	184	12	MHC	MHC	NNP
cord-285778-80baxwgc	184	13	class	class	NN
cord-285778-80baxwgc	185	1	I	-PRON-	PRP
cord-285778-80baxwgc	185	2	molecules	molecule	NNS
cord-285778-80baxwgc	186	1	(	(	-LRB-
cord-285778-80baxwgc	186	2	Fig	Fig	NNP
cord-285778-80baxwgc	186	3	.	.	NNP
cord-285778-80baxwgc	186	4	1	1	CD
cord-285778-80baxwgc	186	5	-	-	HYPH
cord-285778-80baxwgc	186	6	5B	5b	CD
cord-285778-80baxwgc	186	7	)	)	-RRB-
cord-285778-80baxwgc	186	8	.	.	.
cord-285778-80baxwgc	187	1	The	the	DT
cord-285778-80baxwgc	187	2	activated	activate	VBN
cord-285778-80baxwgc	187	3	Tc	Tc	NNP
cord-285778-80baxwgc	187	4	cell	cell	NN
cord-285778-80baxwgc	187	5	proliferates	proliferate	VBZ
cord-285778-80baxwgc	187	6	and	and	CC
cord-285778-80baxwgc	187	7	differentiates	differentiate	VBZ
cord-285778-80baxwgc	187	8	into	into	IN
cord-285778-80baxwgc	187	9	identical	identical	JJ
cord-285778-80baxwgc	187	10	daughter	daughter	NN
cord-285778-80baxwgc	187	11	effector	effector	NN
cord-285778-80baxwgc	187	12	cells	cell	NNS
cord-285778-80baxwgc	187	13	called	call	VBN
cord-285778-80baxwgc	187	14	,	,	,
cord-285778-80baxwgc	187	15	for	for	IN
cord-285778-80baxwgc	187	16	historical	historical	JJ
cord-285778-80baxwgc	187	17	reasons	reason	NNS
cord-285778-80baxwgc	187	18	,	,	,
cord-285778-80baxwgc	187	19	CTLs	CTLs	NNP
cord-285778-80baxwgc	187	20	(	(	-LRB-
cord-285778-80baxwgc	187	21	cytotoxic	cytotoxic	JJ
cord-285778-80baxwgc	187	22	T	t	NN
cord-285778-80baxwgc	187	23	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	187	24	)	)	-RRB-
cord-285778-80baxwgc	187	25	.	.	.
cord-285778-80baxwgc	188	1	CTLs	CTLs	NNP
cord-285778-80baxwgc	188	2	can	can	MD
cord-285778-80baxwgc	188	3	lyse	lyse	VB
cord-285778-80baxwgc	188	4	any	any	DT
cord-285778-80baxwgc	188	5	host	host	NN
cord-285778-80baxwgc	188	6	cell	cell	NN
cord-285778-80baxwgc	188	7	displaying	display	VBG
cord-285778-80baxwgc	188	8	the	the	DT
cord-285778-80baxwgc	188	9	same	same	JJ
cord-285778-80baxwgc	188	10	peptide	peptide	NN
cord-285778-80baxwgc	188	11	-	-	HYPH
cord-285778-80baxwgc	188	12	MHC	MHC	NNP
cord-285778-80baxwgc	188	13	class	class	NN
cord-285778-80baxwgc	188	14	I	-PRON-	PRP
cord-285778-80baxwgc	188	15	complex	complex	VBP
cord-285778-80baxwgc	188	16	recognized	recognize	VBN
cord-285778-80baxwgc	188	17	by	by	IN
cord-285778-80baxwgc	188	18	the	the	DT
cord-285778-80baxwgc	188	19	original	original	JJ
cord-285778-80baxwgc	188	20	Tc	Tc	NNP
cord-285778-80baxwgc	188	21	cell	cell	NN
cord-285778-80baxwgc	188	22	.	.	.
cord-285778-80baxwgc	189	1	MHC	MHC	NNP
cord-285778-80baxwgc	189	2	class	class	NN
cord-285778-80baxwgc	190	1	I	-PRON-	PRP
cord-285778-80baxwgc	190	2	molecules	molecule	NNS
cord-285778-80baxwgc	190	3	are	be	VBP
cord-285778-80baxwgc	190	4	expressed	express	VBN
cord-285778-80baxwgc	190	5	on	on	IN
cord-285778-80baxwgc	190	6	almost	almost	RB
cord-285778-80baxwgc	190	7	all	all	DT
cord-285778-80baxwgc	190	8	body	body	NN
cord-285778-80baxwgc	190	9	cells	cell	NNS
cord-285778-80baxwgc	190	10	,	,	,
cord-285778-80baxwgc	190	11	making	make	VBG
cord-285778-80baxwgc	190	12	them	-PRON-	PRP
cord-285778-80baxwgc	190	13	all	all	DT
cord-285778-80baxwgc	190	14	potential	potential	JJ
cord-285778-80baxwgc	190	15	targets	target	NNS
cord-285778-80baxwgc	190	16	for	for	IN
cord-285778-80baxwgc	190	17	CTL	CTL	NNP
cord-285778-80baxwgc	190	18	-	-	HYPH
cord-285778-80baxwgc	190	19	mediated	mediate	VBN
cord-285778-80baxwgc	190	20	lysis	lysis	NN
cord-285778-80baxwgc	190	21	.	.	.
cord-285778-80baxwgc	191	1	However	however	RB
cord-285778-80baxwgc	191	2	,	,	,
cord-285778-80baxwgc	191	3	unlike	unlike	IN
cord-285778-80baxwgc	191	4	DCs	dc	NNS
cord-285778-80baxwgc	191	5	,	,	,
cord-285778-80baxwgc	191	6	most	most	JJS
cord-285778-80baxwgc	191	7	host	host	NN
cord-285778-80baxwgc	191	8	cells	cell	NNS
cord-285778-80baxwgc	191	9	can	can	MD
cord-285778-80baxwgc	191	10	not	not	RB
cord-285778-80baxwgc	191	11	phagocytose	phagocytose	VB
cord-285778-80baxwgc	191	12	extracellular	extracellular	JJ
cord-285778-80baxwgc	191	13	entities	entity	NNS
cord-285778-80baxwgc	191	14	.	.	.
cord-285778-80baxwgc	192	1	It	-PRON-	PRP
cord-285778-80baxwgc	192	2	is	be	VBZ
cord-285778-80baxwgc	192	3	therefore	therefore	RB
cord-285778-80baxwgc	192	4	only	only	RB
cord-285778-80baxwgc	192	5	after	after	IN
cord-285778-80baxwgc	192	6	infection	infection	NN
cord-285778-80baxwgc	192	7	with	with	IN
cord-285778-80baxwgc	192	8	an	an	DT
cord-285778-80baxwgc	192	9	intracellular	intracellular	JJ
cord-285778-80baxwgc	192	10	pathogen	pathogen	NN
cord-285778-80baxwgc	192	11	that	that	IN
cord-285778-80baxwgc	192	12	a	a	DT
cord-285778-80baxwgc	192	13	host	host	NN
cord-285778-80baxwgc	192	14	cell	cell	NN
cord-285778-80baxwgc	192	15	displays	display	VBZ
cord-285778-80baxwgc	192	16	an	an	DT
cord-285778-80baxwgc	192	17	antigenic	antigenic	JJ
cord-285778-80baxwgc	192	18	pMHC	pmhc	NN
cord-285778-80baxwgc	192	19	complex	complex	NN
cord-285778-80baxwgc	192	20	that	that	WDT
cord-285778-80baxwgc	192	21	can	can	MD
cord-285778-80baxwgc	192	22	be	be	VB
cord-285778-80baxwgc	192	23	recognized	recognize	VBN
cord-285778-80baxwgc	192	24	by	by	IN
cord-285778-80baxwgc	192	25	the	the	DT
cord-285778-80baxwgc	192	26	TCR	TCR	NNP
cord-285778-80baxwgc	192	27	of	of	IN
cord-285778-80baxwgc	192	28	first	first	RB
cord-285778-80baxwgc	192	29	the	the	DT
cord-285778-80baxwgc	192	30	Tc	Tc	NNP
cord-285778-80baxwgc	192	31	cell	cell	NN
cord-285778-80baxwgc	192	32	and	and	CC
cord-285778-80baxwgc	192	33	then	then	RB
cord-285778-80baxwgc	192	34	its	-PRON-	PRP$
cord-285778-80baxwgc	192	35	daughter	daughter	NN
cord-285778-80baxwgc	192	36	CTLs	CTLs	NNP
cord-285778-80baxwgc	192	37	.	.	.
cord-285778-80baxwgc	193	1	The	the	DT
cord-285778-80baxwgc	193	2	cell	cell	NN
cord-285778-80baxwgc	193	3	-	-	HYPH
cord-285778-80baxwgc	193	4	mediated	mediate	VBN
cord-285778-80baxwgc	193	5	immunity	immunity	NN
cord-285778-80baxwgc	193	6	directed	direct	VBN
cord-285778-80baxwgc	193	7	against	against	IN
cord-285778-80baxwgc	193	8	such	such	JJ
cord-285778-80baxwgc	193	9	infected	infected	JJ
cord-285778-80baxwgc	193	10	host	host	NN
cord-285778-80baxwgc	193	11	cells	cell	NNS
cord-285778-80baxwgc	193	12	is	be	VBZ
cord-285778-80baxwgc	193	13	critical	critical	JJ
cord-285778-80baxwgc	193	14	to	to	IN
cord-285778-80baxwgc	193	15	the	the	DT
cord-285778-80baxwgc	193	16	clearance	clearance	NN
cord-285778-80baxwgc	193	17	of	of	IN
cord-285778-80baxwgc	193	18	intracellular	intracellular	JJ
cord-285778-80baxwgc	193	19	pathogens	pathogen	NNS
cord-285778-80baxwgc	193	20	.	.	.
cord-285778-80baxwgc	194	1	Th	th	DT
cord-285778-80baxwgc	194	2	cells	cell	NNS
cord-285778-80baxwgc	194	3	recognize	recognize	VBP
cord-285778-80baxwgc	194	4	antigenic	antigenic	JJ
cord-285778-80baxwgc	194	5	peptides	peptide	NNS
cord-285778-80baxwgc	194	6	that	that	IN
cord-285778-80baxwgc	194	7	a	a	DT
cord-285778-80baxwgc	194	8	DC	DC	NNP
cord-285778-80baxwgc	194	9	has	have	VBZ
cord-285778-80baxwgc	194	10	presented	present	VBN
cord-285778-80baxwgc	194	11	on	on	IN
cord-285778-80baxwgc	194	12	MHC	MHC	NNP
cord-285778-80baxwgc	194	13	class	class	NN
cord-285778-80baxwgc	194	14	II	II	NNP
cord-285778-80baxwgc	194	15	molecules	molecule	NNS
cord-285778-80baxwgc	194	16	(	(	-LRB-
cord-285778-80baxwgc	194	17	Fig	Fig	NNP
cord-285778-80baxwgc	194	18	.	.	.
cord-285778-80baxwgc	194	19	1	1	CD
cord-285778-80baxwgc	194	20	-	-	HYPH
cord-285778-80baxwgc	194	21	5C	5c	CD
cord-285778-80baxwgc	194	22	)	)	-RRB-
cord-285778-80baxwgc	194	23	.	.	.
cord-285778-80baxwgc	195	1	The	the	DT
cord-285778-80baxwgc	195	2	activated	activate	VBN
cord-285778-80baxwgc	195	3	Th	Th	NNP
cord-285778-80baxwgc	195	4	cell	cell	NN
cord-285778-80baxwgc	195	5	proliferates	proliferate	VBZ
cord-285778-80baxwgc	195	6	and	and	CC
cord-285778-80baxwgc	195	7	differentiates	differentiate	VBZ
cord-285778-80baxwgc	195	8	into	into	IN
cord-285778-80baxwgc	195	9	identical	identical	JJ
cord-285778-80baxwgc	195	10	Th	Th	NNP
cord-285778-80baxwgc	195	11	effector	effector	NN
cord-285778-80baxwgc	195	12	cells	cell	NNS
cord-285778-80baxwgc	195	13	that	that	WDT
cord-285778-80baxwgc	195	14	can	can	MD
cord-285778-80baxwgc	195	15	recognize	recognize	VB
cord-285778-80baxwgc	195	16	the	the	DT
cord-285778-80baxwgc	195	17	same	same	JJ
cord-285778-80baxwgc	195	18	pMHC	pmhc	JJ
cord-285778-80baxwgc	195	19	structure	structure	NN
cord-285778-80baxwgc	195	20	that	that	WDT
cord-285778-80baxwgc	195	21	activated	activate	VBD
cord-285778-80baxwgc	195	22	the	the	DT
cord-285778-80baxwgc	195	23	original	original	JJ
cord-285778-80baxwgc	195	24	Th	Th	NNP
cord-285778-80baxwgc	195	25	cell	cell	NN
cord-285778-80baxwgc	195	26	.	.	.
cord-285778-80baxwgc	196	1	However	however	RB
cord-285778-80baxwgc	196	2	,	,	,
cord-285778-80baxwgc	196	3	MHC	MHC	NNP
cord-285778-80baxwgc	196	4	class	class	NN
cord-285778-80baxwgc	196	5	II	II	NNP
cord-285778-80baxwgc	196	6	molecules	molecule	NNS
cord-285778-80baxwgc	196	7	are	be	VBP
cord-285778-80baxwgc	196	8	expressed	express	VBN
cord-285778-80baxwgc	196	9	only	only	RB
cord-285778-80baxwgc	196	10	by	by	IN
cord-285778-80baxwgc	196	11	certain	certain	JJ
cord-285778-80baxwgc	196	12	cell	cell	NN
cord-285778-80baxwgc	196	13	types	type	NNS
cord-285778-80baxwgc	196	14	that	that	WDT
cord-285778-80baxwgc	196	15	can	can	MD
cord-285778-80baxwgc	196	16	act	act	VB
cord-285778-80baxwgc	196	17	as	as	IN
cord-285778-80baxwgc	196	18	specialized	specialized	JJ
cord-285778-80baxwgc	196	19	antigen	antigen	NN
cord-285778-80baxwgc	196	20	-	-	HYPH
cord-285778-80baxwgc	196	21	presenting	present	VBG
cord-285778-80baxwgc	196	22	cells	cell	NNS
cord-285778-80baxwgc	196	23	(	(	-LRB-
cord-285778-80baxwgc	196	24	APCs	apc	NNS
cord-285778-80baxwgc	196	25	)	)	-RRB-
cord-285778-80baxwgc	196	26	,	,	,
cord-285778-80baxwgc	196	27	including	include	VBG
cord-285778-80baxwgc	196	28	DCs	dc	NNS
cord-285778-80baxwgc	196	29	,	,	,
cord-285778-80baxwgc	196	30	macrophages	macrophage	NNS
cord-285778-80baxwgc	196	31	and	and	CC
cord-285778-80baxwgc	196	32	activated	activate	VBN
cord-285778-80baxwgc	196	33	B	b	NN
cord-285778-80baxwgc	196	34	cells	cell	NNS
cord-285778-80baxwgc	196	35	.	.	.
cord-285778-80baxwgc	197	1	In	in	IN
cord-285778-80baxwgc	197	2	the	the	DT
cord-285778-80baxwgc	197	3	course	course	NN
cord-285778-80baxwgc	197	4	of	of	IN
cord-285778-80baxwgc	197	5	a	a	DT
cord-285778-80baxwgc	197	6	pathogen	pathogen	NN
cord-285778-80baxwgc	197	7	attack	attack	NN
cord-285778-80baxwgc	197	8	,	,	,
cord-285778-80baxwgc	197	9	APCs	apc	NNS
cord-285778-80baxwgc	197	10	can	can	MD
cord-285778-80baxwgc	197	11	capture	capture	VB
cord-285778-80baxwgc	197	12	the	the	DT
cord-285778-80baxwgc	197	13	pathogen	pathogen	NN
cord-285778-80baxwgc	197	14	and/or	and/or	CC
cord-285778-80baxwgc	197	15	its	-PRON-	PRP$
cord-285778-80baxwgc	197	16	products	product	NNS
cord-285778-80baxwgc	197	17	or	or	CC
cord-285778-80baxwgc	197	18	components	component	NNS
cord-285778-80baxwgc	197	19	,	,	,
cord-285778-80baxwgc	197	20	and	and	CC
cord-285778-80baxwgc	197	21	then	then	RB
cord-285778-80baxwgc	197	22	display	display	NN
cord-285778-80baxwgc	197	23	peptides	peptide	NNS
cord-285778-80baxwgc	197	24	derived	derive	VBN
cord-285778-80baxwgc	197	25	from	from	IN
cord-285778-80baxwgc	197	26	its	-PRON-	PRP$
cord-285778-80baxwgc	197	27	antigens	antigen	NNS
cord-285778-80baxwgc	197	28	on	on	IN
cord-285778-80baxwgc	197	29	MHC	MHC	NNP
cord-285778-80baxwgc	197	30	class	class	NN
cord-285778-80baxwgc	197	31	II	II	NNP
cord-285778-80baxwgc	197	32	.	.	.
cord-285778-80baxwgc	198	1	When	when	WRB
cord-285778-80baxwgc	198	2	the	the	DT
cord-285778-80baxwgc	198	3	TCR	TCR	NNP
cord-285778-80baxwgc	198	4	of	of	IN
cord-285778-80baxwgc	198	5	a	a	DT
cord-285778-80baxwgc	198	6	Th	Th	NNP
cord-285778-80baxwgc	198	7	effector	effector	NN
cord-285778-80baxwgc	198	8	cell	cell	NN
cord-285778-80baxwgc	198	9	recognizes	recognize	VBZ
cord-285778-80baxwgc	198	10	this	this	DT
cord-285778-80baxwgc	198	11	pMHC	pmhc	JJ
cord-285778-80baxwgc	198	12	structure	structure	NN
cord-285778-80baxwgc	198	13	,	,	,
cord-285778-80baxwgc	198	14	the	the	DT
cord-285778-80baxwgc	198	15	cell	cell	NN
cord-285778-80baxwgc	198	16	is	be	VBZ
cord-285778-80baxwgc	198	17	stimulated	stimulate	VBN
cord-285778-80baxwgc	198	18	to	to	TO
cord-285778-80baxwgc	198	19	produce	produce	VB
cord-285778-80baxwgc	198	20	cytokines	cytokine	NNS
cord-285778-80baxwgc	198	21	that	that	WDT
cord-285778-80baxwgc	198	22	assist	assist	VBP
cord-285778-80baxwgc	198	23	B	b	NN
cord-285778-80baxwgc	198	24	cells	cell	NNS
cord-285778-80baxwgc	198	25	and	and	CC
cord-285778-80baxwgc	198	26	Tc	Tc	NNP
cord-285778-80baxwgc	198	27	cells	cell	NNS
cord-285778-80baxwgc	198	28	to	to	TO
cord-285778-80baxwgc	198	29	become	become	VB
cord-285778-80baxwgc	198	30	fully	fully	RB
cord-285778-80baxwgc	198	31	activated	activate	VBN
cord-285778-80baxwgc	198	32	.	.	.
cord-285778-80baxwgc	199	1	In	in	IN
cord-285778-80baxwgc	199	2	this	this	DT
cord-285778-80baxwgc	199	3	way	way	NN
cord-285778-80baxwgc	199	4	,	,	,
cord-285778-80baxwgc	199	5	Th	Th	NNP
cord-285778-80baxwgc	199	6	cells	cell	NNS
cord-285778-80baxwgc	199	7	contribute	contribute	VBP
cord-285778-80baxwgc	199	8	to	to	IN
cord-285778-80baxwgc	199	9	both	both	CC
cord-285778-80baxwgc	199	10	humoral	humoral	JJ
cord-285778-80baxwgc	199	11	and	and	CC
cord-285778-80baxwgc	199	12	cell	cell	NN
cord-285778-80baxwgc	199	13	-	-	HYPH
cord-285778-80baxwgc	199	14	mediated	mediate	VBN
cord-285778-80baxwgc	199	15	adaptive	adaptive	JJ
cord-285778-80baxwgc	199	16	responses	response	NNS
cord-285778-80baxwgc	199	17	,	,	,
cord-285778-80baxwgc	199	18	and	and	CC
cord-285778-80baxwgc	199	19	are	be	VBP
cord-285778-80baxwgc	199	20	thus	thus	RB
cord-285778-80baxwgc	199	21	crucial	crucial	JJ
cord-285778-80baxwgc	199	22	for	for	IN
cord-285778-80baxwgc	199	23	protection	protection	NN
cord-285778-80baxwgc	199	24	against	against	IN
cord-285778-80baxwgc	199	25	many	many	JJ
cord-285778-80baxwgc	199	26	extracellular	extracellular	JJ
cord-285778-80baxwgc	199	27	and	and	CC
cord-285778-80baxwgc	199	28	intracellular	intracellular	JJ
cord-285778-80baxwgc	199	29	pathogens	pathogen	NNS
cord-285778-80baxwgc	199	30	.	.	.
cord-285778-80baxwgc	200	1	In	in	IN
cord-285778-80baxwgc	200	2	addition	addition	NN
cord-285778-80baxwgc	200	3	,	,	,
cord-285778-80baxwgc	200	4	cytokines	cytokine	NNS
cord-285778-80baxwgc	200	5	secreted	secrete	VBN
cord-285778-80baxwgc	200	6	by	by	IN
cord-285778-80baxwgc	200	7	Th	Th	NNP
cord-285778-80baxwgc	200	8	cells	cell	NNS
cord-285778-80baxwgc	200	9	stimulate	stimulate	VBP
cord-285778-80baxwgc	200	10	innate	innate	JJ
cord-285778-80baxwgc	200	11	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	200	12	,	,	,
cord-285778-80baxwgc	200	13	thereby	thereby	RB
cord-285778-80baxwgc	200	14	reinforcing	reinforce	VBG
cord-285778-80baxwgc	200	15	this	this	DT
cord-285778-80baxwgc	200	16	arm	arm	NN
cord-285778-80baxwgc	200	17	of	of	IN
cord-285778-80baxwgc	200	18	immunity	immunity	NN
cord-285778-80baxwgc	200	19	.	.	.
cord-285778-80baxwgc	201	1	The	the	DT
cord-285778-80baxwgc	201	2	combined	combined	JJ
cord-285778-80baxwgc	201	3	efforts	effort	NNS
cord-285778-80baxwgc	201	4	of	of	IN
cord-285778-80baxwgc	201	5	Tc	Tc	NNP
cord-285778-80baxwgc	201	6	,	,	,
cord-285778-80baxwgc	201	7	Th	Th	NNP
cord-285778-80baxwgc	201	8	and	and	CC
cord-285778-80baxwgc	201	9	B	b	NN
cord-285778-80baxwgc	201	10	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	201	11	and	and	CC
cord-285778-80baxwgc	201	12	many	many	JJ
cord-285778-80baxwgc	201	13	types	type	NNS
cord-285778-80baxwgc	201	14	of	of	IN
cord-285778-80baxwgc	201	15	innate	innate	JJ
cord-285778-80baxwgc	201	16	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	201	17	may	may	MD
cord-285778-80baxwgc	201	18	be	be	VB
cord-285778-80baxwgc	201	19	necessary	necessary	JJ
cord-285778-80baxwgc	201	20	to	to	TO
cord-285778-80baxwgc	201	21	eliminate	eliminate	VB
cord-285778-80baxwgc	201	22	a	a	DT
cord-285778-80baxwgc	201	23	particularly	particularly	RB
cord-285778-80baxwgc	201	24	wily	wily	JJ
cord-285778-80baxwgc	201	25	invader	invader	NN
cord-285778-80baxwgc	201	26	.	.	.
cord-285778-80baxwgc	202	1	The	the	DT
cord-285778-80baxwgc	202	2	innate	innate	JJ
cord-285778-80baxwgc	202	3	response	response	NN
cord-285778-80baxwgc	202	4	deals	deal	NNS
cord-285778-80baxwgc	202	5	with	with	IN
cord-285778-80baxwgc	202	6	a	a	DT
cord-285778-80baxwgc	202	7	given	give	VBN
cord-285778-80baxwgc	202	8	threat	threat	NN
cord-285778-80baxwgc	202	9	in	in	IN
cord-285778-80baxwgc	202	10	a	a	DT
cord-285778-80baxwgc	202	11	very	very	RB
cord-285778-80baxwgc	202	12	similar	similar	JJ
cord-285778-80baxwgc	202	13	way	way	NN
cord-285778-80baxwgc	203	1	each	each	DT
cord-285778-80baxwgc	203	2	time	time	NN
cord-285778-80baxwgc	203	3	it	-PRON-	PRP
cord-285778-80baxwgc	203	4	enters	enter	VBZ
cord-285778-80baxwgc	203	5	the	the	DT
cord-285778-80baxwgc	203	6	body	body	NN
cord-285778-80baxwgc	203	7	.	.	.
cord-285778-80baxwgc	204	1	In	in	IN
cord-285778-80baxwgc	204	2	contrast	contrast	NN
cord-285778-80baxwgc	204	3	,	,	,
cord-285778-80baxwgc	204	4	the	the	DT
cord-285778-80baxwgc	204	5	adaptive	adaptive	JJ
cord-285778-80baxwgc	204	6	system	system	NN
cord-285778-80baxwgc	204	7	can	can	MD
cord-285778-80baxwgc	204	8	"	"	``
cord-285778-80baxwgc	204	9	remember	remember	VB
cord-285778-80baxwgc	204	10	"	"	''
cord-285778-80baxwgc	204	11	that	that	IN
cord-285778-80baxwgc	204	12	it	-PRON-	PRP
cord-285778-80baxwgc	204	13	has	have	VBZ
cord-285778-80baxwgc	204	14	seen	see	VBN
cord-285778-80baxwgc	204	15	a	a	DT
cord-285778-80baxwgc	204	16	particular	particular	JJ
cord-285778-80baxwgc	204	17	antigen	antigen	NN
cord-285778-80baxwgc	204	18	before	before	RB
cord-285778-80baxwgc	204	19	.	.	.
cord-285778-80baxwgc	205	1	This	this	DT
cord-285778-80baxwgc	205	2	immunological	immunological	JJ
cord-285778-80baxwgc	205	3	memory	memory	NN
cord-285778-80baxwgc	205	4	means	mean	VBZ
cord-285778-80baxwgc	205	5	that	that	IN
cord-285778-80baxwgc	205	6	an	an	DT
cord-285778-80baxwgc	205	7	enhanced	enhanced	JJ
cord-285778-80baxwgc	205	8	adaptive	adaptive	JJ
cord-285778-80baxwgc	205	9	response	response	NN
cord-285778-80baxwgc	205	10	is	be	VBZ
cord-285778-80baxwgc	205	11	mounted	mount	VBN
cord-285778-80baxwgc	205	12	upon	upon	IN
cord-285778-80baxwgc	205	13	a	a	DT
cord-285778-80baxwgc	205	14	second	second	JJ
cord-285778-80baxwgc	205	15	and	and	CC
cord-285778-80baxwgc	205	16	subsequent	subsequent	JJ
cord-285778-80baxwgc	205	17	exposures	exposure	NNS
cord-285778-80baxwgc	205	18	to	to	IN
cord-285778-80baxwgc	205	19	a	a	DT
cord-285778-80baxwgc	205	20	given	give	VBN
cord-285778-80baxwgc	205	21	pathogen	pathogen	NN
cord-285778-80baxwgc	205	22	,	,	,
cord-285778-80baxwgc	205	23	so	so	IN
cord-285778-80baxwgc	205	24	that	that	IN
cord-285778-80baxwgc	205	25	signs	sign	NNS
cord-285778-80baxwgc	205	26	of	of	IN
cord-285778-80baxwgc	205	27	clinical	clinical	JJ
cord-285778-80baxwgc	205	28	illness	illness	NN
cord-285778-80baxwgc	205	29	are	be	VBP
cord-285778-80baxwgc	205	30	mitigated	mitigate	VBN
cord-285778-80baxwgc	205	31	or	or	CC
cord-285778-80baxwgc	205	32	prevented	prevent	VBN
cord-285778-80baxwgc	205	33	.	.	.
cord-285778-80baxwgc	206	1	In	in	IN
cord-285778-80baxwgc	206	2	other	other	JJ
cord-285778-80baxwgc	206	3	words	word	NNS
cord-285778-80baxwgc	206	4	,	,	,
cord-285778-80baxwgc	206	5	immunity	immunity	NN
cord-285778-80baxwgc	206	6	is	be	VBZ
cord-285778-80baxwgc	206	7	achieved	achieve	VBN
cord-285778-80baxwgc	206	8	because	because	IN
cord-285778-80baxwgc	206	9	the	the	DT
cord-285778-80baxwgc	206	10	body	body	NN
cord-285778-80baxwgc	206	11	has	have	VBZ
cord-285778-80baxwgc	206	12	effectively	effectively	RB
cord-285778-80baxwgc	206	13	"	"	``
cord-285778-80baxwgc	206	14	adapted	adapt	VBN
cord-285778-80baxwgc	206	15	"	"	''
cord-285778-80baxwgc	206	16	its	-PRON-	PRP$
cord-285778-80baxwgc	206	17	defenses	defense	NNS
cord-285778-80baxwgc	206	18	and	and	CC
cord-285778-80baxwgc	206	19	acquired	acquire	VBD
cord-285778-80baxwgc	206	20	the	the	DT
cord-285778-80baxwgc	206	21	ability	ability	NN
cord-285778-80baxwgc	206	22	to	to	TO
cord-285778-80baxwgc	206	23	exclude	exclude	VB
cord-285778-80baxwgc	206	24	a	a	DT
cord-285778-80baxwgc	206	25	particular	particular	JJ
cord-285778-80baxwgc	206	26	pathogen	pathogen	NN
cord-285778-80baxwgc	206	27	.	.	.
cord-285778-80baxwgc	207	1	Immunological	immunological	JJ
cord-285778-80baxwgc	207	2	memory	memory	NN
cord-285778-80baxwgc	207	3	arises	arise	VBZ
cord-285778-80baxwgc	207	4	in	in	IN
cord-285778-80baxwgc	207	5	the	the	DT
cord-285778-80baxwgc	207	6	following	following	JJ
cord-285778-80baxwgc	207	7	way	way	NN
cord-285778-80baxwgc	207	8	.	.	.
cord-285778-80baxwgc	208	1	A	a	DT
cord-285778-80baxwgc	208	2	constant	constant	JJ
cord-285778-80baxwgc	208	3	supply	supply	NN
cord-285778-80baxwgc	208	4	of	of	IN
cord-285778-80baxwgc	208	5	resting	rest	VBG
cord-285778-80baxwgc	208	6	B	b	NN
cord-285778-80baxwgc	208	7	and	and	CC
cord-285778-80baxwgc	208	8	T	t	NN
cord-285778-80baxwgc	208	9	cells	cell	NNS
cord-285778-80baxwgc	208	10	is	be	VBZ
cord-285778-80baxwgc	208	11	maintained	maintain	VBN
cord-285778-80baxwgc	208	12	throughout	throughout	IN
cord-285778-80baxwgc	208	13	the	the	DT
cord-285778-80baxwgc	208	14	body	body	NN
cord-285778-80baxwgc	208	15	,	,	,
cord-285778-80baxwgc	208	16	with	with	IN
cord-285778-80baxwgc	208	17	each	each	DT
cord-285778-80baxwgc	208	18	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	208	19	expressing	express	VBG
cord-285778-80baxwgc	208	20	its	-PRON-	PRP$
cord-285778-80baxwgc	208	21	complement	complement	NN
cord-285778-80baxwgc	208	22	of	of	IN
cord-285778-80baxwgc	208	23	unique	unique	JJ
cord-285778-80baxwgc	208	24	antigen	antigen	NN
cord-285778-80baxwgc	208	25	receptor	receptor	NN
cord-285778-80baxwgc	208	26	proteins	protein	NNS
cord-285778-80baxwgc	208	27	.	.	.
cord-285778-80baxwgc	209	1	When	when	WRB
cord-285778-80baxwgc	209	2	a	a	DT
cord-285778-80baxwgc	209	3	pathogen	pathogen	NN
cord-285778-80baxwgc	209	4	antigen	antigen	NN
cord-285778-80baxwgc	209	5	enters	enter	VBZ
cord-285778-80baxwgc	209	6	the	the	DT
cord-285778-80baxwgc	209	7	Antibody	Antibody	NNP
cord-285778-80baxwgc	209	8	production	production	NN
cord-285778-80baxwgc	209	9	by	by	IN
cord-285778-80baxwgc	209	10	B	b	NN
cord-285778-80baxwgc	209	11	cells	cell	NNS
cord-285778-80baxwgc	209	12	is	be	VBZ
cord-285778-80baxwgc	209	13	described	describe	VBN
cord-285778-80baxwgc	209	14	in	in	IN
cord-285778-80baxwgc	209	15	detail	detail	NN
cord-285778-80baxwgc	209	16	in	in	IN
cord-285778-80baxwgc	209	17	Chapters	chapter	NNS
cord-285778-80baxwgc	209	18	4	4	CD
cord-285778-80baxwgc	209	19	and	and	CC
cord-285778-80baxwgc	209	20	5	5	CD
cord-285778-80baxwgc	209	21	.	.	.
cord-285778-80baxwgc	209	22	"	"	''
cord-285778-80baxwgc	210	1	MHC	MHC	NNP
cord-285778-80baxwgc	210	2	"	"	``
cord-285778-80baxwgc	210	3	stands	stand	VBZ
cord-285778-80baxwgc	210	4	for	for	IN
cord-285778-80baxwgc	210	5	"	"	``
cord-285778-80baxwgc	210	6	major	major	JJ
cord-285778-80baxwgc	210	7	histocompatibility	histocompatibility	NN
cord-285778-80baxwgc	210	8	complex	complex	NN
cord-285778-80baxwgc	210	9	,	,	,
cord-285778-80baxwgc	210	10	"	"	''
cord-285778-80baxwgc	210	11	a	a	DT
cord-285778-80baxwgc	210	12	region	region	NN
cord-285778-80baxwgc	210	13	on	on	IN
cord-285778-80baxwgc	210	14	human	human	JJ
cord-285778-80baxwgc	210	15	chromosome	chromosome	NN
cord-285778-80baxwgc	210	16	6	6	CD
cord-285778-80baxwgc	210	17	that	that	WDT
cord-285778-80baxwgc	210	18	contains	contain	VBZ
cord-285778-80baxwgc	210	19	genes	gene	NNS
cord-285778-80baxwgc	210	20	encoding	encode	VBG
cord-285778-80baxwgc	210	21	several	several	JJ
cord-285778-80baxwgc	210	22	types	type	NNS
cord-285778-80baxwgc	210	23	of	of	IN
cord-285778-80baxwgc	210	24	molecules	molecule	NNS
cord-285778-80baxwgc	210	25	vital	vital	JJ
cord-285778-80baxwgc	210	26	for	for	IN
cord-285778-80baxwgc	210	27	the	the	DT
cord-285778-80baxwgc	210	28	adaptive	adaptive	JJ
cord-285778-80baxwgc	210	29	immune	immune	JJ
cord-285778-80baxwgc	210	30	response	response	NN
cord-285778-80baxwgc	210	31	.	.	.
cord-285778-80baxwgc	211	1	MHC	MHC	NNP
cord-285778-80baxwgc	211	2	genes	gene	NNS
cord-285778-80baxwgc	211	3	and	and	CC
cord-285778-80baxwgc	211	4	proteins	protein	NNS
cord-285778-80baxwgc	211	5	are	be	VBP
cord-285778-80baxwgc	211	6	described	describe	VBN
cord-285778-80baxwgc	211	7	in	in	IN
cord-285778-80baxwgc	211	8	detail	detail	NN
cord-285778-80baxwgc	211	9	in	in	IN
cord-285778-80baxwgc	211	10	Chapter	chapter	NN
cord-285778-80baxwgc	211	11	6	6	CD
cord-285778-80baxwgc	211	12	.	.	.
cord-285778-80baxwgc	212	1	body	body	NN
cord-285778-80baxwgc	212	2	for	for	IN
cord-285778-80baxwgc	212	3	the	the	DT
cord-285778-80baxwgc	212	4	first	first	JJ
cord-285778-80baxwgc	212	5	time	time	NN
cord-285778-80baxwgc	212	6	,	,	,
cord-285778-80baxwgc	212	7	a	a	DT
cord-285778-80baxwgc	212	8	process	process	NN
cord-285778-80baxwgc	212	9	of	of	IN
cord-285778-80baxwgc	212	10	clonal	clonal	JJ
cord-285778-80baxwgc	212	11	selection	selection	NN
cord-285778-80baxwgc	212	12	takes	take	VBZ
cord-285778-80baxwgc	212	13	place	place	NN
cord-285778-80baxwgc	212	14	in	in	IN
cord-285778-80baxwgc	212	15	which	which	WDT
cord-285778-80baxwgc	212	16	only	only	RB
cord-285778-80baxwgc	212	17	those	those	DT
cord-285778-80baxwgc	212	18	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	212	19	bearing	bear	VBG
cord-285778-80baxwgc	212	20	receptors	receptor	NNS
cord-285778-80baxwgc	212	21	specific	specific	JJ
cord-285778-80baxwgc	212	22	for	for	IN
cord-285778-80baxwgc	212	23	that	that	DT
cord-285778-80baxwgc	212	24	antigen	antigen	NN
cord-285778-80baxwgc	212	25	are	be	VBP
cord-285778-80baxwgc	212	26	triggered	trigger	VBN
cord-285778-80baxwgc	212	27	to	to	TO
cord-285778-80baxwgc	212	28	respond	respond	VB
cord-285778-80baxwgc	212	29	.	.	.
cord-285778-80baxwgc	213	1	The	the	DT
cord-285778-80baxwgc	213	2	selected	select	VBN
cord-285778-80baxwgc	213	3	cells	cell	NNS
cord-285778-80baxwgc	213	4	leave	leave	VBP
cord-285778-80baxwgc	213	5	the	the	DT
cord-285778-80baxwgc	213	6	resting	rest	VBG
cord-285778-80baxwgc	213	7	state	state	NN
cord-285778-80baxwgc	213	8	and	and	CC
cord-285778-80baxwgc	213	9	multiply	multiply	VB
cord-285778-80baxwgc	213	10	to	to	TO
cord-285778-80baxwgc	213	11	generate	generate	VB
cord-285778-80baxwgc	213	12	daughter	daughter	NN
cord-285778-80baxwgc	213	13	cells	cell	NNS
cord-285778-80baxwgc	213	14	all	all	DT
cord-285778-80baxwgc	213	15	expressing	express	VBG
cord-285778-80baxwgc	213	16	the	the	DT
cord-285778-80baxwgc	213	17	same	same	JJ
cord-285778-80baxwgc	213	18	antigen	antigen	NN
cord-285778-80baxwgc	213	19	-	-	HYPH
cord-285778-80baxwgc	213	20	specific	specific	JJ
cord-285778-80baxwgc	213	21	BCR	BCR	NNP
cord-285778-80baxwgc	213	22	or	or	CC
cord-285778-80baxwgc	213	23	TCR	TCR	NNP
cord-285778-80baxwgc	213	24	.	.	.
cord-285778-80baxwgc	214	1	The	the	DT
cord-285778-80baxwgc	214	2	differentiation	differentiation	NN
cord-285778-80baxwgc	214	3	of	of	IN
cord-285778-80baxwgc	214	4	these	these	DT
cord-285778-80baxwgc	214	5	daughter	daughter	NN
cord-285778-80baxwgc	214	6	cells	cell	NNS
cord-285778-80baxwgc	214	7	gives	give	VBZ
cord-285778-80baxwgc	214	8	rise	rise	NN
cord-285778-80baxwgc	214	9	to	to	IN
cord-285778-80baxwgc	214	10	the	the	DT
cord-285778-80baxwgc	214	11	short	short	RB
cord-285778-80baxwgc	214	12	-	-	HYPH
cord-285778-80baxwgc	214	13	lived	live	VBN
cord-285778-80baxwgc	214	14	effector	effector	NN
cord-285778-80baxwgc	214	15	cells	cell	NNS
cord-285778-80baxwgc	214	16	required	require	VBN
cord-285778-80baxwgc	214	17	to	to	TO
cord-285778-80baxwgc	214	18	eliminate	eliminate	VB
cord-285778-80baxwgc	214	19	the	the	DT
cord-285778-80baxwgc	214	20	pathogen	pathogen	NN
cord-285778-80baxwgc	214	21	,	,	,
cord-285778-80baxwgc	214	22	as	as	RB
cord-285778-80baxwgc	214	23	well	well	RB
cord-285778-80baxwgc	214	24	as	as	IN
cord-285778-80baxwgc	214	25	long	long	RB
cord-285778-80baxwgc	214	26	-	-	HYPH
cord-285778-80baxwgc	214	27	lived	live	VBN
cord-285778-80baxwgc	214	28	memory	memory	NN
cord-285778-80baxwgc	214	29	cells	cell	NNS
cord-285778-80baxwgc	214	30	that	that	WDT
cord-285778-80baxwgc	214	31	persist	persist	VBP
cord-285778-80baxwgc	214	32	in	in	IN
cord-285778-80baxwgc	214	33	the	the	DT
cord-285778-80baxwgc	214	34	tissues	tissue	NNS
cord-285778-80baxwgc	214	35	essentially	essentially	RB
cord-285778-80baxwgc	214	36	in	in	IN
cord-285778-80baxwgc	214	37	a	a	DT
cord-285778-80baxwgc	214	38	resting	rest	VBG
cord-285778-80baxwgc	214	39	state	state	NN
cord-285778-80baxwgc	214	40	until	until	IN
cord-285778-80baxwgc	214	41	a	a	DT
cord-285778-80baxwgc	214	42	subsequent	subsequent	JJ
cord-285778-80baxwgc	214	43	exposure	exposure	NN
cord-285778-80baxwgc	214	44	to	to	IN
cord-285778-80baxwgc	214	45	the	the	DT
cord-285778-80baxwgc	214	46	same	same	JJ
cord-285778-80baxwgc	214	47	pathogen	pathogen	NN
cord-285778-80baxwgc	214	48	(	(	-LRB-
cord-285778-80baxwgc	214	49	Fig	Fig	NNP
cord-285778-80baxwgc	214	50	.	.	NNP
cord-285778-80baxwgc	214	51	1	1	CD
cord-285778-80baxwgc	214	52	-	-	SYM
cord-285778-80baxwgc	214	53	6	6	CD
cord-285778-80baxwgc	214	54	)	)	-RRB-
cord-285778-80baxwgc	214	55	.	.	.
cord-285778-80baxwgc	215	1	The	the	DT
cord-285778-80baxwgc	215	2	attack	attack	NN
cord-285778-80baxwgc	215	3	on	on	IN
cord-285778-80baxwgc	215	4	the	the	DT
cord-285778-80baxwgc	215	5	pathogen	pathogen	NN
cord-285778-80baxwgc	215	6	by	by	IN
cord-285778-80baxwgc	215	7	this	this	DT
cord-285778-80baxwgc	215	8	first	first	JJ
cord-285778-80baxwgc	215	9	round	round	NN
cord-285778-80baxwgc	215	10	of	of	IN
cord-285778-80baxwgc	215	11	effector	effector	NN
cord-285778-80baxwgc	215	12	cells	cell	NNS
cord-285778-80baxwgc	215	13	is	be	VBZ
cord-285778-80baxwgc	215	14	called	call	VBN
cord-285778-80baxwgc	215	15	the	the	DT
cord-285778-80baxwgc	215	16	primary	primary	JJ
cord-285778-80baxwgc	215	17	immune	immune	JJ
cord-285778-80baxwgc	215	18	response	response	NN
cord-285778-80baxwgc	215	19	.	.	.
cord-285778-80baxwgc	216	1	The	the	DT
cord-285778-80baxwgc	216	2	second	second	JJ
cord-285778-80baxwgc	216	3	(	(	-LRB-
cord-285778-80baxwgc	216	4	or	or	CC
cord-285778-80baxwgc	216	5	subsequent	subsequent	JJ
cord-285778-80baxwgc	216	6	)	)	-RRB-
cord-285778-80baxwgc	216	7	time	time	NN
cord-285778-80baxwgc	216	8	that	that	WDT
cord-285778-80baxwgc	216	9	the	the	DT
cord-285778-80baxwgc	216	10	particular	particular	JJ
cord-285778-80baxwgc	216	11	pathogen	pathogen	NN
cord-285778-80baxwgc	216	12	enters	enter	VBZ
cord-285778-80baxwgc	216	13	the	the	DT
cord-285778-80baxwgc	216	14	body	body	NN
cord-285778-80baxwgc	216	15	,	,	,
cord-285778-80baxwgc	216	16	it	-PRON-	PRP
cord-285778-80baxwgc	216	17	is	be	VBZ
cord-285778-80baxwgc	216	18	met	meet	VBN
cord-285778-80baxwgc	216	19	by	by	IN
cord-285778-80baxwgc	216	20	an	an	DT
cord-285778-80baxwgc	216	21	expanded	expand	VBN
cord-285778-80baxwgc	216	22	army	army	NN
cord-285778-80baxwgc	216	23	of	of	IN
cord-285778-80baxwgc	216	24	clonally	clonally	RB
cord-285778-80baxwgc	216	25	selected	select	VBN
cord-285778-80baxwgc	216	26	,	,	,
cord-285778-80baxwgc	216	27	antigen	antigen	NN
cord-285778-80baxwgc	216	28	-	-	HYPH
cord-285778-80baxwgc	216	29	specific	specific	JJ
cord-285778-80baxwgc	216	30	memory	memory	NN
cord-285778-80baxwgc	216	31	cells	cell	NNS
cord-285778-80baxwgc	216	32	that	that	WDT
cord-285778-80baxwgc	216	33	undergo	undergo	VBP
cord-285778-80baxwgc	216	34	much	much	RB
cord-285778-80baxwgc	216	35	more	more	RBR
cord-285778-80baxwgc	216	36	rapid	rapid	JJ
cord-285778-80baxwgc	216	37	differentiation	differentiation	NN
cord-285778-80baxwgc	216	38	into	into	IN
cord-285778-80baxwgc	216	39	effector	effector	NN
cord-285778-80baxwgc	216	40	cells	cell	NNS
cord-285778-80baxwgc	216	41	than	than	IN
cord-285778-80baxwgc	216	42	occurred	occur	VBD
cord-285778-80baxwgc	216	43	during	during	IN
cord-285778-80baxwgc	216	44	the	the	DT
cord-285778-80baxwgc	216	45	first	first	JJ
cord-285778-80baxwgc	216	46	antigen	antigen	NN
cord-285778-80baxwgc	216	47	encounter	encounter	NN
cord-285778-80baxwgc	216	48	.	.	.
cord-285778-80baxwgc	217	1	The	the	DT
cord-285778-80baxwgc	217	2	result	result	NN
cord-285778-80baxwgc	217	3	is	be	VBZ
cord-285778-80baxwgc	217	4	a	a	DT
cord-285778-80baxwgc	217	5	stronger	strong	JJR
cord-285778-80baxwgc	217	6	and	and	CC
cord-285778-80baxwgc	217	7	faster	fast	JJR
cord-285778-80baxwgc	217	8	secondary	secondary	JJ
cord-285778-80baxwgc	217	9	immune	immune	JJ
cord-285778-80baxwgc	217	10	response	response	NN
cord-285778-80baxwgc	217	11	that	that	WDT
cord-285778-80baxwgc	217	12	eliminates	eliminate	VBZ
cord-285778-80baxwgc	217	13	the	the	DT
cord-285778-80baxwgc	217	14	pathogen	pathogen	NN
cord-285778-80baxwgc	217	15	before	before	IN
cord-285778-80baxwgc	217	16	it	-PRON-	PRP
cord-285778-80baxwgc	217	17	can	can	MD
cord-285778-80baxwgc	217	18	cause	cause	VB
cord-285778-80baxwgc	217	19	illness	illness	NN
cord-285778-80baxwgc	217	20	.	.	.
cord-285778-80baxwgc	218	1	New	new	JJ
cord-285778-80baxwgc	218	2	populations	population	NNS
cord-285778-80baxwgc	218	3	of	of	IN
cord-285778-80baxwgc	218	4	memory	memory	NN
cord-285778-80baxwgc	218	5	cells	cell	NNS
cord-285778-80baxwgc	218	6	are	be	VBP
cord-285778-80baxwgc	218	7	also	also	RB
cord-285778-80baxwgc	218	8	produced	produce	VBN
cord-285778-80baxwgc	218	9	during	during	IN
cord-285778-80baxwgc	218	10	the	the	DT
cord-285778-80baxwgc	218	11	secondary	secondary	JJ
cord-285778-80baxwgc	218	12	response	response	NN
cord-285778-80baxwgc	218	13	,	,	,
cord-285778-80baxwgc	218	14	ensuring	ensure	VBG
cord-285778-80baxwgc	218	15	that	that	IN
cord-285778-80baxwgc	218	16	the	the	DT
cord-285778-80baxwgc	218	17	host	host	NN
cord-285778-80baxwgc	218	18	maintains	maintain	VBZ
cord-285778-80baxwgc	218	19	long	long	JJ
cord-285778-80baxwgc	218	20	-	-	HYPH
cord-285778-80baxwgc	218	21	term	term	NN
cord-285778-80baxwgc	218	22	or	or	CC
cord-285778-80baxwgc	218	23	even	even	RB
cord-285778-80baxwgc	218	24	lifelong	lifelong	JJ
cord-285778-80baxwgc	218	25	immunity	immunity	NN
cord-285778-80baxwgc	218	26	to	to	IN
cord-285778-80baxwgc	218	27	that	that	DT
cord-285778-80baxwgc	218	28	pathogen	pathogen	NN
cord-285778-80baxwgc	218	29	.	.	.
cord-285778-80baxwgc	219	1	The	the	DT
cord-285778-80baxwgc	219	2	degree	degree	NN
cord-285778-80baxwgc	219	3	of	of	IN
cord-285778-80baxwgc	219	4	diversity	diversity	NN
cord-285778-80baxwgc	219	5	of	of	IN
cord-285778-80baxwgc	219	6	antigens	antigen	NNS
cord-285778-80baxwgc	219	7	recognized	recognize	VBN
cord-285778-80baxwgc	219	8	also	also	RB
cord-285778-80baxwgc	219	9	distinguishes	distinguish	VBZ
cord-285778-80baxwgc	219	10	the	the	DT
cord-285778-80baxwgc	219	11	adaptive	adaptive	JJ
cord-285778-80baxwgc	219	12	response	response	NN
cord-285778-80baxwgc	219	13	from	from	IN
cord-285778-80baxwgc	219	14	the	the	DT
cord-285778-80baxwgc	219	15	innate	innate	JJ
cord-285778-80baxwgc	219	16	response	response	NN
cord-285778-80baxwgc	219	17	.	.	.
cord-285778-80baxwgc	220	1	Whereas	whereas	IN
cord-285778-80baxwgc	220	2	the	the	DT
cord-285778-80baxwgc	220	3	innate	innate	JJ
cord-285778-80baxwgc	220	4	immune	immune	JJ
cord-285778-80baxwgc	220	5	system	system	NN
cord-285778-80baxwgc	220	6	exhibits	exhibit	VBZ
cord-285778-80baxwgc	220	7	a	a	DT
cord-285778-80baxwgc	220	8	genetically	genetically	RB
cord-285778-80baxwgc	220	9	fixed	fix	VBN
cord-285778-80baxwgc	220	10	and	and	CC
cord-285778-80baxwgc	220	11	finite	finite	JJ
cord-285778-80baxwgc	220	12	capacity	capacity	NN
cord-285778-80baxwgc	220	13	for	for	IN
cord-285778-80baxwgc	220	14	antigen	antigen	NN
cord-285778-80baxwgc	220	15	recognition	recognition	NN
cord-285778-80baxwgc	220	16	,	,	,
cord-285778-80baxwgc	220	17	the	the	DT
cord-285778-80baxwgc	220	18	recognition	recognition	NN
cord-285778-80baxwgc	220	19	capacity	capacity	NN
cord-285778-80baxwgc	220	20	of	of	IN
cord-285778-80baxwgc	220	21	the	the	DT
cord-285778-80baxwgc	220	22	adaptive	adaptive	JJ
cord-285778-80baxwgc	220	23	immune	immune	JJ
cord-285778-80baxwgc	220	24	system	system	NN
cord-285778-80baxwgc	220	25	is	be	VBZ
cord-285778-80baxwgc	220	26	nearly	nearly	RB
cord-285778-80baxwgc	220	27	limitless	limitless	JJ
cord-285778-80baxwgc	220	28	.	.	.
cord-285778-80baxwgc	221	1	In	in	IN
cord-285778-80baxwgc	221	2	fact	fact	NN
cord-285778-80baxwgc	221	3	,	,	,
cord-285778-80baxwgc	221	4	our	-PRON-	PRP$
cord-285778-80baxwgc	221	5	bodies	body	NNS
cord-285778-80baxwgc	221	6	are	be	VBP
cord-285778-80baxwgc	221	7	capable	capable	JJ
cord-285778-80baxwgc	221	8	of	of	IN
cord-285778-80baxwgc	221	9	recognizing	recognize	VBG
cord-285778-80baxwgc	221	10	totally	totally	RB
cord-285778-80baxwgc	221	11	synthetic	synthetic	JJ
cord-285778-80baxwgc	221	12	antigens	antigen	NNS
cord-285778-80baxwgc	221	13	that	that	WDT
cord-285778-80baxwgc	221	14	do	do	VBP
cord-285778-80baxwgc	221	15	not	not	RB
cord-285778-80baxwgc	221	16	occur	occur	VB
cord-285778-80baxwgc	221	17	in	in	IN
cord-285778-80baxwgc	221	18	nature	nature	NN
cord-285778-80baxwgc	221	19	.	.	.
cord-285778-80baxwgc	222	1	This	this	DT
cord-285778-80baxwgc	222	2	huge	huge	JJ
cord-285778-80baxwgc	222	3	diversity	diversity	NN
cord-285778-80baxwgc	222	4	arises	arise	VBZ
cord-285778-80baxwgc	222	5	from	from	IN
cord-285778-80baxwgc	222	6	the	the	DT
cord-285778-80baxwgc	222	7	combined	combined	JJ
cord-285778-80baxwgc	222	8	actions	action	NNS
cord-285778-80baxwgc	222	9	of	of	IN
cord-285778-80baxwgc	222	10	several	several	JJ
cord-285778-80baxwgc	222	11	genetic	genetic	JJ
cord-285778-80baxwgc	222	12	mechanisms	mechanism	NNS
cord-285778-80baxwgc	222	13	that	that	WDT
cord-285778-80baxwgc	222	14	affect	affect	VBP
cord-285778-80baxwgc	222	15	the	the	DT
cord-285778-80baxwgc	222	16	genes	gene	NNS
cord-285778-80baxwgc	222	17	encoding	encode	VBG
cord-285778-80baxwgc	222	18	the	the	DT
cord-285778-80baxwgc	222	19	 	 	_SP
cord-285778-80baxwgc	223	1	When	when	WRB
cord-285778-80baxwgc	223	2	antigen	antigen	NN
cord-285778-80baxwgc	223	3	X	X	NNP
cord-285778-80baxwgc	223	4	enters	enter	VBZ
cord-285778-80baxwgc	223	5	the	the	DT
cord-285778-80baxwgc	223	6	body	body	NN
cord-285778-80baxwgc	223	7	,	,	,
cord-285778-80baxwgc	223	8	only	only	RB
cord-285778-80baxwgc	223	9	those	those	DT
cord-285778-80baxwgc	223	10	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	223	11	with	with	IN
cord-285778-80baxwgc	223	12	receptors	receptor	NNS
cord-285778-80baxwgc	223	13	that	that	WDT
cord-285778-80baxwgc	223	14	specifically	specifically	RB
cord-285778-80baxwgc	223	15	recognize	recognize	VBP
cord-285778-80baxwgc	223	16	X	X	NNP
cord-285778-80baxwgc	223	17	will	will	MD
cord-285778-80baxwgc	223	18	be	be	VB
cord-285778-80baxwgc	223	19	selected	select	VBN
cord-285778-80baxwgc	223	20	to	to	TO
cord-285778-80baxwgc	223	21	proliferate	proliferate	VB
cord-285778-80baxwgc	223	22	and	and	CC
cord-285778-80baxwgc	223	23	generate	generate	VB
cord-285778-80baxwgc	223	24	daughter	daughter	NN
cord-285778-80baxwgc	223	25	Clonal	Clonal	NNP
cord-285778-80baxwgc	223	26	selection	selection	NN
cord-285778-80baxwgc	223	27	is	be	VBZ
cord-285778-80baxwgc	223	28	explained	explain	VBN
cord-285778-80baxwgc	223	29	in	in	IN
cord-285778-80baxwgc	223	30	detail	detail	NN
cord-285778-80baxwgc	223	31	in	in	IN
cord-285778-80baxwgc	223	32	Chapter	chapter	NN
cord-285778-80baxwgc	223	33	5	5	CD
cord-285778-80baxwgc	223	34	for	for	IN
cord-285778-80baxwgc	223	35	B	b	NN
cord-285778-80baxwgc	223	36	cells	cell	NNS
cord-285778-80baxwgc	223	37	and	and	CC
cord-285778-80baxwgc	223	38	in	in	IN
cord-285778-80baxwgc	223	39	Chapter	chapter	NN
cord-285778-80baxwgc	223	40	9	9	CD
cord-285778-80baxwgc	223	41	for	for	IN
cord-285778-80baxwgc	223	42	T	t	NN
cord-285778-80baxwgc	223	43	cells	cell	NNS
cord-285778-80baxwgc	223	44	.	.	.
cord-285778-80baxwgc	224	1	NOTE	note	NN
cord-285778-80baxwgc	224	2	:	:	:
cord-285778-80baxwgc	225	1	The	the	DT
cord-285778-80baxwgc	225	2	generation	generation	NN
cord-285778-80baxwgc	225	3	of	of	IN
cord-285778-80baxwgc	225	4	protective	protective	JJ
cord-285778-80baxwgc	225	5	memory	memory	NN
cord-285778-80baxwgc	225	6	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	225	7	is	be	VBZ
cord-285778-80baxwgc	225	8	the	the	DT
cord-285778-80baxwgc	225	9	basis	basis	NN
cord-285778-80baxwgc	225	10	of	of	IN
cord-285778-80baxwgc	225	11	vaccination	vaccination	NN
cord-285778-80baxwgc	225	12	.	.	.
cord-285778-80baxwgc	226	1	A	a	DT
cord-285778-80baxwgc	226	2	healthy	healthy	JJ
cord-285778-80baxwgc	226	3	person	person	NN
cord-285778-80baxwgc	226	4	is	be	VBZ
cord-285778-80baxwgc	226	5	immunized	immunize	VBN
cord-285778-80baxwgc	226	6	with	with	IN
cord-285778-80baxwgc	226	7	a	a	DT
cord-285778-80baxwgc	226	8	vaccine	vaccine	NN
cord-285778-80baxwgc	226	9	containing	contain	VBG
cord-285778-80baxwgc	226	10	pathogen	pathogen	NN
cord-285778-80baxwgc	226	11	antigens	antigen	NNS
cord-285778-80baxwgc	226	12	in	in	IN
cord-285778-80baxwgc	226	13	order	order	NN
cord-285778-80baxwgc	226	14	to	to	TO
cord-285778-80baxwgc	226	15	provoke	provoke	VB
cord-285778-80baxwgc	226	16	the	the	DT
cord-285778-80baxwgc	226	17	production	production	NN
cord-285778-80baxwgc	226	18	of	of	IN
cord-285778-80baxwgc	226	19	memory	memory	NN
cord-285778-80baxwgc	226	20	cells	cell	NNS
cord-285778-80baxwgc	226	21	that	that	WDT
cord-285778-80baxwgc	226	22	will	will	MD
cord-285778-80baxwgc	226	23	prevent	prevent	VB
cord-285778-80baxwgc	226	24	disease	disease	NN
cord-285778-80baxwgc	226	25	from	from	IN
cord-285778-80baxwgc	226	26	developing	develop	VBG
cord-285778-80baxwgc	226	27	if	if	IN
cord-285778-80baxwgc	226	28	the	the	DT
cord-285778-80baxwgc	226	29	individual	individual	NN
cord-285778-80baxwgc	226	30	is	be	VBZ
cord-285778-80baxwgc	226	31	ever	ever	RB
cord-285778-80baxwgc	226	32	naturally	naturally	RB
cord-285778-80baxwgc	226	33	infected	infect	VBN
cord-285778-80baxwgc	226	34	by	by	IN
cord-285778-80baxwgc	226	35	that	that	DT
cord-285778-80baxwgc	226	36	pathogen	pathogen	NN
cord-285778-80baxwgc	226	37	.	.	.
cord-285778-80baxwgc	227	1	Vaccination	vaccination	NN
cord-285778-80baxwgc	227	2	is	be	VBZ
cord-285778-80baxwgc	227	3	described	describe	VBN
cord-285778-80baxwgc	227	4	in	in	IN
cord-285778-80baxwgc	227	5	detail	detail	NN
cord-285778-80baxwgc	227	6	in	in	IN
cord-285778-80baxwgc	227	7	Chapter	chapter	NN
cord-285778-80baxwgc	227	8	14	14	CD
cord-285778-80baxwgc	227	9	.	.	.
cord-285778-80baxwgc	228	1	antigen	antigen	NNP
cord-285778-80baxwgc	228	2	receptors	receptor	NNS
cord-285778-80baxwgc	228	3	.	.	.
cord-285778-80baxwgc	229	1	Some	some	DT
cord-285778-80baxwgc	229	2	of	of	IN
cord-285778-80baxwgc	229	3	these	these	DT
cord-285778-80baxwgc	229	4	mechanisms	mechanism	NNS
cord-285778-80baxwgc	229	5	operate	operate	VBP
cord-285778-80baxwgc	229	6	before	before	IN
cord-285778-80baxwgc	229	7	a	a	DT
cord-285778-80baxwgc	229	8	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	229	9	encounters	encounter	VBZ
cord-285778-80baxwgc	229	10	antigen	antigen	NN
cord-285778-80baxwgc	229	11	,	,	,
cord-285778-80baxwgc	229	12	and	and	CC
cord-285778-80baxwgc	229	13	some	some	DT
cord-285778-80baxwgc	229	14	after	after	RB
cord-285778-80baxwgc	229	15	.	.	.
cord-285778-80baxwgc	230	1	The	the	DT
cord-285778-80baxwgc	230	2	primary	primary	JJ
cord-285778-80baxwgc	230	3	source	source	NN
cord-285778-80baxwgc	230	4	of	of	IN
cord-285778-80baxwgc	230	5	antigen	antigen	NN
cord-285778-80baxwgc	230	6	receptor	receptor	NN
cord-285778-80baxwgc	230	7	diversity	diversity	NN
cord-285778-80baxwgc	230	8	is	be	VBZ
cord-285778-80baxwgc	230	9	a	a	DT
cord-285778-80baxwgc	230	10	gene	gene	NN
cord-285778-80baxwgc	230	11	rearrangement	rearrangement	NN
cord-285778-80baxwgc	230	12	process	process	NN
cord-285778-80baxwgc	230	13	that	that	WDT
cord-285778-80baxwgc	230	14	occurs	occur	VBZ
cord-285778-80baxwgc	230	15	during	during	IN
cord-285778-80baxwgc	230	16	the	the	DT
cord-285778-80baxwgc	230	17	development	development	NN
cord-285778-80baxwgc	230	18	of	of	IN
cord-285778-80baxwgc	230	19	B	b	NN
cord-285778-80baxwgc	230	20	cells	cell	NNS
cord-285778-80baxwgc	230	21	and	and	CC
cord-285778-80baxwgc	230	22	T	t	NN
cord-285778-80baxwgc	230	23	cells	cell	NNS
cord-285778-80baxwgc	230	24	prior	prior	RB
cord-285778-80baxwgc	230	25	to	to	TO
cord-285778-80baxwgc	230	26	encounter	encounter	VB
cord-285778-80baxwgc	230	27	with	with	IN
cord-285778-80baxwgc	230	28	antigen	antigen	NN
cord-285778-80baxwgc	230	29	.	.	.
cord-285778-80baxwgc	231	1	The	the	DT
cord-285778-80baxwgc	231	2	genes	gene	NNS
cord-285778-80baxwgc	231	3	encoding	encode	VBG
cord-285778-80baxwgc	231	4	antigen	antigen	NN
cord-285778-80baxwgc	231	5	receptors	receptor	NNS
cord-285778-80baxwgc	231	6	are	be	VBP
cord-285778-80baxwgc	231	7	not	not	RB
cord-285778-80baxwgc	231	8	individual	individual	JJ
cord-285778-80baxwgc	231	9	continuous	continuous	JJ
cord-285778-80baxwgc	231	10	entities	entity	NNS
cord-285778-80baxwgc	231	11	.	.	.
cord-285778-80baxwgc	232	1	Rather	rather	RB
cord-285778-80baxwgc	232	2	,	,	,
cord-285778-80baxwgc	232	3	the	the	DT
cord-285778-80baxwgc	232	4	BCR	BCR	NNP
cord-285778-80baxwgc	232	5	and	and	CC
cord-285778-80baxwgc	232	6	TCR	TCR	NNP
cord-285778-80baxwgc	232	7	genes	gene	NNS
cord-285778-80baxwgc	232	8	are	be	VBP
cord-285778-80baxwgc	232	9	assembled	assemble	VBN
cord-285778-80baxwgc	232	10	from	from	IN
cord-285778-80baxwgc	232	11	a	a	DT
cord-285778-80baxwgc	232	12	large	large	JJ
cord-285778-80baxwgc	232	13	collection	collection	NN
cord-285778-80baxwgc	232	14	of	of	IN
cord-285778-80baxwgc	232	15	pre	pre	JJ
cord-285778-80baxwgc	232	16	-	-	JJ
cord-285778-80baxwgc	232	17	existing	existing	JJ
cord-285778-80baxwgc	232	18	gene	gene	NN
cord-285778-80baxwgc	232	19	segments	segment	NNS
cord-285778-80baxwgc	232	20	by	by	IN
cord-285778-80baxwgc	232	21	a	a	DT
cord-285778-80baxwgc	232	22	mechanism	mechanism	NN
cord-285778-80baxwgc	232	23	called	call	VBN
cord-285778-80baxwgc	232	24	somatic	somatic	JJ
cord-285778-80baxwgc	232	25	recombination	recombination	NN
cord-285778-80baxwgc	232	26	.	.	.
cord-285778-80baxwgc	233	1	A	a	DT
cord-285778-80baxwgc	233	2	single	single	JJ
cord-285778-80baxwgc	233	3	,	,	,
cord-285778-80baxwgc	233	4	random	random	JJ
cord-285778-80baxwgc	233	5	combination	combination	NN
cord-285778-80baxwgc	233	6	of	of	IN
cord-285778-80baxwgc	233	7	gene	gene	NN
cord-285778-80baxwgc	233	8	segments	segment	NNS
cord-285778-80baxwgc	233	9	is	be	VBZ
cord-285778-80baxwgc	233	10	thus	thus	RB
cord-285778-80baxwgc	233	11	created	create	VBN
cord-285778-80baxwgc	233	12	in	in	IN
cord-285778-80baxwgc	233	13	each	each	DT
cord-285778-80baxwgc	233	14	developing	develop	VBG
cord-285778-80baxwgc	233	15	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	233	16	.	.	.
cord-285778-80baxwgc	234	1	As	as	IN
cord-285778-80baxwgc	234	2	a	a	DT
cord-285778-80baxwgc	234	3	result	result	NN
cord-285778-80baxwgc	234	4	,	,	,
cord-285778-80baxwgc	234	5	a	a	DT
cord-285778-80baxwgc	234	6	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	234	7	population	population	NN
cord-285778-80baxwgc	234	8	is	be	VBZ
cord-285778-80baxwgc	234	9	generated	generate	VBN
cord-285778-80baxwgc	234	10	in	in	IN
cord-285778-80baxwgc	234	11	which	which	WDT
cord-285778-80baxwgc	234	12	the	the	DT
cord-285778-80baxwgc	234	13	antigen	antigen	NN
cord-285778-80baxwgc	234	14	receptor	receptor	NN
cord-285778-80baxwgc	234	15	proteins	protein	NNS
cord-285778-80baxwgc	234	16	are	be	VBP
cord-285778-80baxwgc	234	17	vastly	vastly	RB
cord-285778-80baxwgc	234	18	diverse	diverse	JJ
cord-285778-80baxwgc	234	19	in	in	IN
cord-285778-80baxwgc	234	20	specificity	specificity	NN
cord-285778-80baxwgc	234	21	because	because	IN
cord-285778-80baxwgc	234	22	they	-PRON-	PRP
cord-285778-80baxwgc	234	23	are	be	VBP
cord-285778-80baxwgc	234	24	encoded	encode	VBN
cord-285778-80baxwgc	234	25	by	by	IN
cord-285778-80baxwgc	234	26	hundreds	hundred	NNS
cord-285778-80baxwgc	234	27	of	of	IN
cord-285778-80baxwgc	234	28	thousands	thousand	NNS
cord-285778-80baxwgc	234	29	of	of	IN
cord-285778-80baxwgc	234	30	different	different	JJ
cord-285778-80baxwgc	234	31	DNA	dna	NN
cord-285778-80baxwgc	234	32	sequences	sequence	NNS
cord-285778-80baxwgc	234	33	.	.	.
cord-285778-80baxwgc	235	1	In	in	IN
cord-285778-80baxwgc	235	2	the	the	DT
cord-285778-80baxwgc	235	3	case	case	NN
cord-285778-80baxwgc	235	4	of	of	IN
cord-285778-80baxwgc	235	5	B	b	NN
cord-285778-80baxwgc	235	6	cells	cell	NNS
cord-285778-80baxwgc	235	7	,	,	,
cord-285778-80baxwgc	235	8	additional	additional	JJ
cord-285778-80baxwgc	235	9	mutational	mutational	JJ
cord-285778-80baxwgc	235	10	mechanisms	mechanism	NNS
cord-285778-80baxwgc	235	11	operate	operate	VBP
cord-285778-80baxwgc	235	12	that	that	WDT
cord-285778-80baxwgc	235	13	result	result	VBP
cord-285778-80baxwgc	235	14	in	in	IN
cord-285778-80baxwgc	235	15	further	further	JJ
cord-285778-80baxwgc	235	16	structural	structural	JJ
cord-285778-80baxwgc	235	17	diversification	diversification	NN
cord-285778-80baxwgc	235	18	of	of	IN
cord-285778-80baxwgc	235	19	antibody	antibody	NN
cord-285778-80baxwgc	235	20	proteins	protein	NNS
cord-285778-80baxwgc	235	21	.	.	.
cord-285778-80baxwgc	236	1	The	the	DT
cord-285778-80baxwgc	236	2	sheer	sheer	JJ
cord-285778-80baxwgc	236	3	numbers	number	NNS
cord-285778-80baxwgc	236	4	of	of	IN
cord-285778-80baxwgc	236	5	B	B	NNP
cord-285778-80baxwgc	236	6	and	and	CC
cord-285778-80baxwgc	236	7	T	T	NNP
cord-285778-80baxwgc	236	8	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	236	9	clones	clone	NNS
cord-285778-80baxwgc	236	10	generated	generate	VBN
cord-285778-80baxwgc	236	11	in	in	IN
cord-285778-80baxwgc	236	12	a	a	DT
cord-285778-80baxwgc	236	13	healthy	healthy	JJ
cord-285778-80baxwgc	236	14	individual	individual	JJ
cord-285778-80baxwgc	236	15	guarantee	guarantee	NN
cord-285778-80baxwgc	236	16	that	that	IN
cord-285778-80baxwgc	236	17	there	there	EX
cord-285778-80baxwgc	236	18	will	will	MD
cord-285778-80baxwgc	236	19	be	be	VB
cord-285778-80baxwgc	236	20	at	at	RB
cord-285778-80baxwgc	236	21	least	least	RBS
cord-285778-80baxwgc	236	22	one	one	CD
cord-285778-80baxwgc	236	23	clone	clone	NN
cord-285778-80baxwgc	236	24	expressing	express	VBG
cord-285778-80baxwgc	236	25	a	a	DT
cord-285778-80baxwgc	236	26	unique	unique	JJ
cord-285778-80baxwgc	236	27	receptor	receptor	NN
cord-285778-80baxwgc	236	28	sequence	sequence	NN
cord-285778-80baxwgc	236	29	for	for	IN
cord-285778-80baxwgc	236	30	every	every	DT
cord-285778-80baxwgc	236	31	antigen	antigen	NN
cord-285778-80baxwgc	236	32	encountered	encounter	VBN
cord-285778-80baxwgc	236	33	during	during	IN
cord-285778-80baxwgc	236	34	the	the	DT
cord-285778-80baxwgc	236	35	host	host	NN
cord-285778-80baxwgc	236	36	's	's	POS
cord-285778-80baxwgc	236	37	life	life	NN
cord-285778-80baxwgc	236	38	span	span	NN
cord-285778-80baxwgc	236	39	.	.	.
cord-285778-80baxwgc	237	1	As	as	IN
cord-285778-80baxwgc	237	2	alluded	allude	VBN
cord-285778-80baxwgc	237	3	to	to	IN
cord-285778-80baxwgc	237	4	previously	previously	RB
cord-285778-80baxwgc	237	5	,	,	,
cord-285778-80baxwgc	237	6	these	these	DT
cord-285778-80baxwgc	237	7	clones	clone	NNS
cord-285778-80baxwgc	237	8	,	,	,
cord-285778-80baxwgc	237	9	with	with	IN
cord-285778-80baxwgc	237	10	their	-PRON-	PRP$
cord-285778-80baxwgc	237	11	array	array	NN
cord-285778-80baxwgc	237	12	of	of	IN
cord-285778-80baxwgc	237	13	antigen	antigen	NN
cord-285778-80baxwgc	237	14	receptor	receptor	NN
cord-285778-80baxwgc	237	15	specificities	specificity	NNS
cord-285778-80baxwgc	237	16	,	,	,
cord-285778-80baxwgc	237	17	are	be	VBP
cord-285778-80baxwgc	237	18	collectively	collectively	RB
cord-285778-80baxwgc	237	19	called	call	VBN
cord-285778-80baxwgc	237	20	the	the	DT
cord-285778-80baxwgc	237	21	individual	individual	NN
cord-285778-80baxwgc	237	22	's	's	POS
cord-285778-80baxwgc	237	23	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	237	24	repertoire	repertoire	NN
cord-285778-80baxwgc	237	25	.	.	.
cord-285778-80baxwgc	238	1	The	the	DT
cord-285778-80baxwgc	238	2	generation	generation	NN
cord-285778-80baxwgc	238	3	of	of	IN
cord-285778-80baxwgc	238	4	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	238	5	clones	clone	NNS
cord-285778-80baxwgc	238	6	that	that	WDT
cord-285778-80baxwgc	238	7	can	can	MD
cord-285778-80baxwgc	238	8	theoretically	theoretically	RB
cord-285778-80baxwgc	238	9	recognize	recognize	VB
cord-285778-80baxwgc	238	10	any	any	DT
cord-285778-80baxwgc	238	11	antigen	antigen	NN
cord-285778-80baxwgc	238	12	in	in	IN
cord-285778-80baxwgc	238	13	the	the	DT
cord-285778-80baxwgc	238	14	universe	universe	NN
cord-285778-80baxwgc	238	15	raises	raise	VBZ
cord-285778-80baxwgc	238	16	the	the	DT
cord-285778-80baxwgc	238	17	question	question	NN
cord-285778-80baxwgc	238	18	of	of	IN
cord-285778-80baxwgc	238	19	how	how	WRB
cord-285778-80baxwgc	238	20	the	the	DT
cord-285778-80baxwgc	238	21	body	body	NN
cord-285778-80baxwgc	238	22	avoids	avoid	VBZ
cord-285778-80baxwgc	238	23	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	238	24	attacks	attack	NNS
cord-285778-80baxwgc	238	25	on	on	IN
cord-285778-80baxwgc	238	26	molecules	molecule	NNS
cord-285778-80baxwgc	238	27	present	present	JJ
cord-285778-80baxwgc	238	28	in	in	IN
cord-285778-80baxwgc	238	29	its	-PRON-	PRP$
cord-285778-80baxwgc	238	30	tissues	tissue	NNS
cord-285778-80baxwgc	238	31	.	.	.
cord-285778-80baxwgc	239	1	This	this	DT
cord-285778-80baxwgc	239	2	avoidance	avoidance	NN
cord-285778-80baxwgc	239	3	is	be	VBZ
cord-285778-80baxwgc	239	4	called	call	VBN
cord-285778-80baxwgc	239	5	tolerance	tolerance	NN
cord-285778-80baxwgc	239	6	,	,	,
cord-285778-80baxwgc	239	7	the	the	DT
cord-285778-80baxwgc	239	8	fifth	fifth	JJ
cord-285778-80baxwgc	239	9	aspect	aspect	NN
cord-285778-80baxwgc	239	10	in	in	IN
cord-285778-80baxwgc	239	11	which	which	WDT
cord-285778-80baxwgc	239	12	the	the	DT
cord-285778-80baxwgc	239	13	adaptive	adaptive	JJ
cord-285778-80baxwgc	239	14	response	response	NN
cord-285778-80baxwgc	239	15	exhibits	exhibit	VBZ
cord-285778-80baxwgc	239	16	more	more	JJR
cord-285778-80baxwgc	239	17	refinement	refinement	NN
cord-285778-80baxwgc	239	18	than	than	IN
cord-285778-80baxwgc	239	19	the	the	DT
cord-285778-80baxwgc	239	20	innate	innate	JJ
cord-285778-80baxwgc	239	21	response	response	NN
cord-285778-80baxwgc	239	22	.	.	.
cord-285778-80baxwgc	240	1	As	as	IN
cord-285778-80baxwgc	240	2	stated	state	VBN
cord-285778-80baxwgc	240	3	previously	previously	RB
cord-285778-80baxwgc	240	4	,	,	,
cord-285778-80baxwgc	240	5	the	the	DT
cord-285778-80baxwgc	240	6	specificity	specificity	NN
cord-285778-80baxwgc	240	7	of	of	IN
cord-285778-80baxwgc	240	8	each	each	DT
cord-285778-80baxwgc	240	9	antigen	antigen	NN
cord-285778-80baxwgc	240	10	receptor	receptor	NN
cord-285778-80baxwgc	240	11	is	be	VBZ
cord-285778-80baxwgc	240	12	randomly	randomly	RB
cord-285778-80baxwgc	240	13	determined	determine	VBN
cord-285778-80baxwgc	240	14	by	by	IN
cord-285778-80baxwgc	240	15	somatic	somatic	JJ
cord-285778-80baxwgc	240	16	recombination	recombination	NN
cord-285778-80baxwgc	240	17	during	during	IN
cord-285778-80baxwgc	240	18	early	early	JJ
cord-285778-80baxwgc	240	19	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	240	20	development	development	NN
cord-285778-80baxwgc	240	21	.	.	.
cord-285778-80baxwgc	241	1	By	by	IN
cord-285778-80baxwgc	241	2	chance	chance	NN
cord-285778-80baxwgc	241	3	,	,	,
cord-285778-80baxwgc	241	4	some	some	DT
cord-285778-80baxwgc	241	5	of	of	IN
cord-285778-80baxwgc	241	6	the	the	DT
cord-285778-80baxwgc	241	7	genetic	genetic	JJ
cord-285778-80baxwgc	241	8	sequences	sequence	NNS
cord-285778-80baxwgc	241	9	produced	produce	VBN
cord-285778-80baxwgc	241	10	will	will	MD
cord-285778-80baxwgc	241	11	encode	encode	VB
cord-285778-80baxwgc	241	12	receptors	receptor	NNS
cord-285778-80baxwgc	241	13	that	that	WDT
cord-285778-80baxwgc	241	14	recognize	recognize	VBP
cord-285778-80baxwgc	241	15	self	self	NN
cord-285778-80baxwgc	241	16	molecules	molecule	NNS
cord-285778-80baxwgc	241	17	(	(	-LRB-
cord-285778-80baxwgc	241	18	self	self	NN
cord-285778-80baxwgc	241	19	antigens	antigen	NNS
cord-285778-80baxwgc	241	20	)	)	-RRB-
cord-285778-80baxwgc	241	21	.	.	.
cord-285778-80baxwgc	242	1	These	these	DT
cord-285778-80baxwgc	242	2	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	242	3	must	must	MD
cord-285778-80baxwgc	242	4	be	be	VB
cord-285778-80baxwgc	242	5	identified	identify	VBN
cord-285778-80baxwgc	242	6	as	as	IN
cord-285778-80baxwgc	242	7	recognizing	recognize	VBG
cord-285778-80baxwgc	242	8	self	self	NN
cord-285778-80baxwgc	242	9	and	and	CC
cord-285778-80baxwgc	242	10	then	then	RB
cord-285778-80baxwgc	242	11	either	either	CC
cord-285778-80baxwgc	242	12	removed	remove	VBD
cord-285778-80baxwgc	242	13	from	from	IN
cord-285778-80baxwgc	242	14	the	the	DT
cord-285778-80baxwgc	242	15	body	body	NN
cord-285778-80baxwgc	242	16	entirely	entirely	RB
cord-285778-80baxwgc	242	17	,	,	,
cord-285778-80baxwgc	242	18	or	or	CC
cord-285778-80baxwgc	242	19	at	at	IN
cord-285778-80baxwgc	242	20	least	least	RBS
cord-285778-80baxwgc	242	21	inactivated	inactivate	VBN
cord-285778-80baxwgc	242	22	,	,	,
cord-285778-80baxwgc	242	23	to	to	TO
cord-285778-80baxwgc	242	24	ensure	ensure	VB
cord-285778-80baxwgc	242	25	that	that	IN
cord-285778-80baxwgc	242	26	an	an	DT
cord-285778-80baxwgc	242	27	individual	individual	NN
cord-285778-80baxwgc	242	28	has	have	VBZ
cord-285778-80baxwgc	242	29	an	an	DT
cord-285778-80baxwgc	242	30	effective	effective	JJ
cord-285778-80baxwgc	242	31	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	242	32	repertoire	repertoire	NN
cord-285778-80baxwgc	242	33	that	that	WDT
cord-285778-80baxwgc	242	34	does	do	VBZ
cord-285778-80baxwgc	242	35	not	not	RB
cord-285778-80baxwgc	242	36	attack	attack	VB
cord-285778-80baxwgc	242	37	healthy	healthy	JJ
cord-285778-80baxwgc	242	38	tissue	tissue	NN
cord-285778-80baxwgc	242	39	.	.	.
cord-285778-80baxwgc	243	1	Tolerance	tolerance	NN
cord-285778-80baxwgc	243	2	is	be	VBZ
cord-285778-80baxwgc	243	3	established	establish	VBN
cord-285778-80baxwgc	243	4	in	in	IN
cord-285778-80baxwgc	243	5	two	two	CD
cord-285778-80baxwgc	243	6	broad	broad	JJ
cord-285778-80baxwgc	243	7	stages	stage	NNS
cord-285778-80baxwgc	243	8	,	,	,
cord-285778-80baxwgc	243	9	each	each	DT
cord-285778-80baxwgc	243	10	of	of	IN
cord-285778-80baxwgc	243	11	which	which	WDT
cord-285778-80baxwgc	243	12	involves	involve	VBZ
cord-285778-80baxwgc	243	13	multiple	multiple	JJ
cord-285778-80baxwgc	243	14	mechanisms	mechanism	NNS
cord-285778-80baxwgc	243	15	.	.	.
cord-285778-80baxwgc	244	1	The	the	DT
cord-285778-80baxwgc	244	2	first	first	JJ
cord-285778-80baxwgc	244	3	stage	stage	NN
cord-285778-80baxwgc	244	4	,	,	,
cord-285778-80baxwgc	244	5	called	call	VBN
cord-285778-80baxwgc	244	6	central	central	JJ
cord-285778-80baxwgc	244	7	tolerance	tolerance	NN
cord-285778-80baxwgc	244	8	,	,	,
cord-285778-80baxwgc	244	9	occurs	occur	VBZ
cord-285778-80baxwgc	244	10	during	during	IN
cord-285778-80baxwgc	244	11	early	early	JJ
cord-285778-80baxwgc	244	12	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	244	13	development	development	NN
cord-285778-80baxwgc	244	14	.	.	.
cord-285778-80baxwgc	245	1	The	the	DT
cord-285778-80baxwgc	245	2	mechanisms	mechanism	NNS
cord-285778-80baxwgc	245	3	of	of	IN
cord-285778-80baxwgc	245	4	central	central	JJ
cord-285778-80baxwgc	245	5	tolerance	tolerance	NN
cord-285778-80baxwgc	245	6	are	be	VBP
cord-285778-80baxwgc	245	7	designed	design	VBN
cord-285778-80baxwgc	245	8	to	to	TO
cord-285778-80baxwgc	245	9	eliminate	eliminate	VB
cord-285778-80baxwgc	245	10	clones	clone	NNS
cord-285778-80baxwgc	245	11	that	that	WDT
cord-285778-80baxwgc	245	12	recognize	recognize	VBP
cord-285778-80baxwgc	245	13	self	self	NN
cord-285778-80baxwgc	245	14	antigens	antigen	NNS
cord-285778-80baxwgc	245	15	,	,	,
cord-285778-80baxwgc	245	16	thus	thus	RB
cord-285778-80baxwgc	245	17	establishing	establish	VBG
cord-285778-80baxwgc	245	18	a	a	DT
cord-285778-80baxwgc	245	19	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	245	20	repertoire	repertoire	NN
cord-285778-80baxwgc	245	21	that	that	WDT
cord-285778-80baxwgc	245	22	targets	target	VBZ
cord-285778-80baxwgc	245	23	"	"	``
cord-285778-80baxwgc	245	24	non	non	JJ
cord-285778-80baxwgc	245	25	-	-	JJ
cord-285778-80baxwgc	245	26	self	self	JJ
cord-285778-80baxwgc	245	27	.	.	.
cord-285778-80baxwgc	245	28	"	"	''
cord-285778-80baxwgc	246	1	In	in	IN
cord-285778-80baxwgc	246	2	the	the	DT
cord-285778-80baxwgc	246	3	second	second	JJ
cord-285778-80baxwgc	246	4	stage	stage	NN
cord-285778-80baxwgc	246	5	,	,	,
cord-285778-80baxwgc	246	6	called	call	VBN
cord-285778-80baxwgc	246	7	peripheral	peripheral	JJ
cord-285778-80baxwgc	246	8	tolerance	tolerance	NN
cord-285778-80baxwgc	246	9	,	,	,
cord-285778-80baxwgc	246	10	any	any	DT
cord-285778-80baxwgc	246	11	B	b	NN
cord-285778-80baxwgc	246	12	and	and	CC
cord-285778-80baxwgc	246	13	T	t	NN
cord-285778-80baxwgc	246	14	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	246	15	that	that	WDT
cord-285778-80baxwgc	246	16	recognize	recognize	VBP
cord-285778-80baxwgc	246	17	self	self	NN
cord-285778-80baxwgc	246	18	but	but	CC
cord-285778-80baxwgc	246	19	somehow	somehow	RB
cord-285778-80baxwgc	246	20	escaped	escape	VBD
cord-285778-80baxwgc	246	21	the	the	DT
cord-285778-80baxwgc	246	22	screening	screening	NN
cord-285778-80baxwgc	246	23	of	of	IN
cord-285778-80baxwgc	246	24	central	central	JJ
cord-285778-80baxwgc	246	25	tolerance	tolerance	NN
cord-285778-80baxwgc	246	26	and	and	CC
cord-285778-80baxwgc	246	27	completed	complete	VBD
cord-285778-80baxwgc	246	28	their	-PRON-	PRP$
cord-285778-80baxwgc	246	29	development	development	NN
cord-285778-80baxwgc	246	30	are	be	VBP
cord-285778-80baxwgc	246	31	functionally	functionally	RB
cord-285778-80baxwgc	246	32	silenced	silence	VBN
cord-285778-80baxwgc	246	33	by	by	IN
cord-285778-80baxwgc	246	34	another	another	DT
cord-285778-80baxwgc	246	35	set	set	NN
cord-285778-80baxwgc	246	36	of	of	IN
cord-285778-80baxwgc	246	37	inactivating	inactivate	VBG
cord-285778-80baxwgc	246	38	mechanisms	mechanism	NNS
cord-285778-80baxwgc	246	39	.	.	.
cord-285778-80baxwgc	247	1	Although	although	IN
cord-285778-80baxwgc	247	2	we	-PRON-	PRP
cord-285778-80baxwgc	247	3	described	describe	VBD
cord-285778-80baxwgc	247	4	the	the	DT
cord-285778-80baxwgc	247	5	innate	innate	JJ
cord-285778-80baxwgc	247	6	and	and	CC
cord-285778-80baxwgc	247	7	adaptive	adaptive	JJ
cord-285778-80baxwgc	247	8	responses	response	NNS
cord-285778-80baxwgc	247	9	separately	separately	RB
cord-285778-80baxwgc	247	10	in	in	IN
cord-285778-80baxwgc	247	11	the	the	DT
cord-285778-80baxwgc	247	12	preceding	precede	VBG
cord-285778-80baxwgc	247	13	sections	section	NNS
cord-285778-80baxwgc	247	14	,	,	,
cord-285778-80baxwgc	247	15	in	in	IN
cord-285778-80baxwgc	247	16	reality	reality	NN
cord-285778-80baxwgc	247	17	,	,	,
cord-285778-80baxwgc	247	18	they	-PRON-	PRP
cord-285778-80baxwgc	247	19	occur	occur	VBP
cord-285778-80baxwgc	247	20	in	in	IN
cord-285778-80baxwgc	247	21	a	a	DT
cord-285778-80baxwgc	247	22	continuum	continuum	NN
cord-285778-80baxwgc	247	23	that	that	WDT
cord-285778-80baxwgc	247	24	brings	bring	VBZ
cord-285778-80baxwgc	247	25	stronger	strong	JJR
cord-285778-80baxwgc	247	26	and	and	CC
cord-285778-80baxwgc	247	27	stronger	strong	JJR
cord-285778-80baxwgc	247	28	weaponry	weaponry	NN
cord-285778-80baxwgc	247	29	to	to	TO
cord-285778-80baxwgc	247	30	bear	bear	VB
cord-285778-80baxwgc	247	31	when	when	WRB
cord-285778-80baxwgc	247	32	(	(	-LRB-
cord-285778-80baxwgc	247	33	and	and	CC
cord-285778-80baxwgc	247	34	only	only	RB
cord-285778-80baxwgc	247	35	when	when	WRB
cord-285778-80baxwgc	247	36	)	)	-RRB-
cord-285778-80baxwgc	247	37	it	-PRON-	PRP
cord-285778-80baxwgc	247	38	is	be	VBZ
cord-285778-80baxwgc	247	39	needed	need	VBN
cord-285778-80baxwgc	247	40	.	.	.
cord-285778-80baxwgc	248	1	Our	-PRON-	PRP$
cord-285778-80baxwgc	248	2	bodies	body	NNS
cord-285778-80baxwgc	248	3	normally	normally	RB
cord-285778-80baxwgc	248	4	deal	deal	VBP
cord-285778-80baxwgc	248	5	with	with	IN
cord-285778-80baxwgc	248	6	a	a	DT
cord-285778-80baxwgc	248	7	pathogen	pathogen	NN
cord-285778-80baxwgc	248	8	attack	attack	NN
cord-285778-80baxwgc	248	9	in	in	IN
cord-285778-80baxwgc	248	10	three	three	CD
cord-285778-80baxwgc	248	11	broad	broad	JJ
cord-285778-80baxwgc	248	12	and	and	CC
cord-285778-80baxwgc	248	13	overlapping	overlapping	JJ
cord-285778-80baxwgc	248	14	phases	phase	NNS
cord-285778-80baxwgc	248	15	,	,	,
cord-285778-80baxwgc	248	16	two	two	CD
cord-285778-80baxwgc	248	17	of	of	IN
cord-285778-80baxwgc	248	18	which	which	WDT
cord-285778-80baxwgc	248	19	involve	involve	VBP
cord-285778-80baxwgc	248	20	innate	innate	JJ
cord-285778-80baxwgc	248	21	responses	response	NNS
cord-285778-80baxwgc	248	22	and	and	CC
cord-285778-80baxwgc	248	23	the	the	DT
cord-285778-80baxwgc	248	24	last	last	JJ
cord-285778-80baxwgc	248	25	of	of	IN
cord-285778-80baxwgc	248	26	which	which	WDT
cord-285778-80baxwgc	248	27	requires	require	VBZ
cord-285778-80baxwgc	248	28	adaptive	adaptive	JJ
cord-285778-80baxwgc	248	29	immunity	immunity	NN
cord-285778-80baxwgc	248	30	(	(	-LRB-
cord-285778-80baxwgc	248	31	Fig	Fig	NNP
cord-285778-80baxwgc	248	32	.	.	.
cord-285778-80baxwgc	248	33	1	1	CD
cord-285778-80baxwgc	248	34	-	-	SYM
cord-285778-80baxwgc	248	35	7	7	CD
cord-285778-80baxwgc	248	36	)	)	-RRB-
cord-285778-80baxwgc	248	37	.	.	.
cord-285778-80baxwgc	249	1	An	an	DT
cord-285778-80baxwgc	249	2	individual	individual	JJ
cord-285778-80baxwgc	249	3	pathogen	pathogen	NN
cord-285778-80baxwgc	249	4	,	,	,
cord-285778-80baxwgc	249	5	such	such	JJ
cord-285778-80baxwgc	249	6	as	as	IN
cord-285778-80baxwgc	249	7	a	a	DT
cord-285778-80baxwgc	249	8	single	single	JJ
cord-285778-80baxwgc	249	9	influenza	influenza	NN
cord-285778-80baxwgc	249	10	virus	virus	NN
cord-285778-80baxwgc	249	11	particle	particle	NN
cord-285778-80baxwgc	249	12	,	,	,
cord-285778-80baxwgc	249	13	is	be	VBZ
cord-285778-80baxwgc	249	14	dealt	deal	VBN
cord-285778-80baxwgc	249	15	with	with	IN
cord-285778-80baxwgc	249	16	by	by	IN
cord-285778-80baxwgc	249	17	these	these	DT
cord-285778-80baxwgc	249	18	phases	phase	NNS
cord-285778-80baxwgc	249	19	sequentially	sequentially	RB
cord-285778-80baxwgc	249	20	,	,	,
cord-285778-80baxwgc	249	21	but	but	CC
cord-285778-80baxwgc	249	22	because	because	IN
cord-285778-80baxwgc	249	23	the	the	DT
cord-285778-80baxwgc	249	24	actual	actual	JJ
cord-285778-80baxwgc	249	25	assault	assault	NN
cord-285778-80baxwgc	249	26	on	on	IN
cord-285778-80baxwgc	249	27	the	the	DT
cord-285778-80baxwgc	249	28	host	host	NN
cord-285778-80baxwgc	249	29	involves	involve	VBZ
cord-285778-80baxwgc	249	30	billions	billion	NNS
cord-285778-80baxwgc	249	31	of	of	IN
cord-285778-80baxwgc	249	32	such	such	JJ
cord-285778-80baxwgc	249	33	particles	particle	NNS
cord-285778-80baxwgc	249	34	,	,	,
cord-285778-80baxwgc	249	35	not	not	RB
cord-285778-80baxwgc	249	36	every	every	DT
cord-285778-80baxwgc	249	37	particle	particle	NN
cord-285778-80baxwgc	249	38	is	be	VBZ
cord-285778-80baxwgc	249	39	in	in	IN
cord-285778-80baxwgc	249	40	the	the	DT
cord-285778-80baxwgc	249	41	same	same	JJ
cord-285778-80baxwgc	249	42	phase	phase	NN
cord-285778-80baxwgc	249	43	at	at	IN
cord-285778-80baxwgc	249	44	the	the	DT
cord-285778-80baxwgc	249	45	same	same	JJ
cord-285778-80baxwgc	249	46	time	time	NN
cord-285778-80baxwgc	249	47	.	.	.
cord-285778-80baxwgc	250	1	As	as	IN
cord-285778-80baxwgc	250	2	a	a	DT
cord-285778-80baxwgc	250	3	result	result	NN
cord-285778-80baxwgc	250	4	,	,	,
cord-285778-80baxwgc	250	5	in	in	IN
cord-285778-80baxwgc	250	6	the	the	DT
cord-285778-80baxwgc	250	7	host	host	NN
cord-285778-80baxwgc	250	8	as	as	IN
cord-285778-80baxwgc	250	9	a	a	DT
cord-285778-80baxwgc	250	10	whole	whole	NN
cord-285778-80baxwgc	250	11	,	,	,
cord-285778-80baxwgc	250	12	and	and	CC
cord-285778-80baxwgc	250	13	for	for	IN
cord-285778-80baxwgc	250	14	an	an	DT
cord-285778-80baxwgc	250	15	infecting	infect	VBG
cord-285778-80baxwgc	250	16	pathogen	pathogen	NN
cord-285778-80baxwgc	250	17	population	population	NN
cord-285778-80baxwgc	250	18	as	as	IN
cord-285778-80baxwgc	250	19	a	a	DT
cord-285778-80baxwgc	250	20	whole	whole	NN
cord-285778-80baxwgc	250	21	,	,	,
cord-285778-80baxwgc	250	22	all	all	DT
cord-285778-80baxwgc	250	23	three	three	CD
cord-285778-80baxwgc	250	24	phases	phase	NNS
cord-285778-80baxwgc	250	25	may	may	MD
cord-285778-80baxwgc	250	26	be	be	VB
cord-285778-80baxwgc	250	27	happening	happen	VBG
cord-285778-80baxwgc	250	28	concurrently	concurrently	RB
cord-285778-80baxwgc	250	29	.	.	.
cord-285778-80baxwgc	251	1	The	the	DT
cord-285778-80baxwgc	251	2	first	first	JJ
cord-285778-80baxwgc	251	3	phase	phase	NN
cord-285778-80baxwgc	251	4	is	be	VBZ
cord-285778-80baxwgc	251	5	mediated	mediate	VBN
cord-285778-80baxwgc	251	6	by	by	IN
cord-285778-80baxwgc	251	7	the	the	DT
cord-285778-80baxwgc	251	8	innate	innate	JJ
cord-285778-80baxwgc	251	9	physical	physical	JJ
cord-285778-80baxwgc	251	10	barriers	barrier	NNS
cord-285778-80baxwgc	251	11	,	,	,
cord-285778-80baxwgc	251	12	which	which	WDT
cord-285778-80baxwgc	251	13	offer	offer	VBP
cord-285778-80baxwgc	251	14	immediate	immediate	JJ
cord-285778-80baxwgc	251	15	protection	protection	NN
cord-285778-80baxwgc	251	16	.	.	.
cord-285778-80baxwgc	252	1	The	the	DT
cord-285778-80baxwgc	252	2	components	component	NNS
cord-285778-80baxwgc	252	3	making	make	VBG
cord-285778-80baxwgc	252	4	up	up	RP
cord-285778-80baxwgc	252	5	these	these	DT
cord-285778-80baxwgc	252	6	barriers	barrier	NNS
cord-285778-80baxwgc	252	7	(	(	-LRB-
cord-285778-80baxwgc	252	8	skin	skin	NN
cord-285778-80baxwgc	252	9	,	,	,
cord-285778-80baxwgc	252	10	mucosae	mucosae	NNP
cord-285778-80baxwgc	252	11	,	,	,
cord-285778-80baxwgc	252	12	gut	gut	NN
cord-285778-80baxwgc	252	13	enzymes	enzyme	NNS
cord-285778-80baxwgc	252	14	)	)	-RRB-
cord-285778-80baxwgc	252	15	are	be	VBP
cord-285778-80baxwgc	252	16	non	non	JJ
cord-285778-80baxwgc	252	17	-	-	JJ
cord-285778-80baxwgc	252	18	inducible	inducible	JJ
cord-285778-80baxwgc	252	19	in	in	IN
cord-285778-80baxwgc	252	20	that	that	IN
cord-285778-80baxwgc	252	21	they	-PRON-	PRP
cord-285778-80baxwgc	252	22	pre	pre	VBP
cord-285778-80baxwgc	252	23	-	-	VBP
cord-285778-80baxwgc	252	24	exist	exist	VB
cord-285778-80baxwgc	252	25	and	and	CC
cord-285778-80baxwgc	252	26	do	do	VBP
cord-285778-80baxwgc	252	27	not	not	RB
cord-285778-80baxwgc	252	28	develop	develop	VB
cord-285778-80baxwgc	252	29	or	or	CC
cord-285778-80baxwgc	252	30	change	change	VB
cord-285778-80baxwgc	252	31	in	in	IN
cord-285778-80baxwgc	252	32	response	response	NN
cord-285778-80baxwgc	252	33	to	to	IN
cord-285778-80baxwgc	252	34	the	the	DT
cord-285778-80baxwgc	252	35	presence	presence	NN
cord-285778-80baxwgc	252	36	of	of	IN
cord-285778-80baxwgc	252	37	a	a	DT
cord-285778-80baxwgc	252	38	foreign	foreign	JJ
cord-285778-80baxwgc	252	39	entity	entity	NN
cord-285778-80baxwgc	252	40	.	.	.
cord-285778-80baxwgc	253	1	Should	Should	MD
cord-285778-80baxwgc	253	2	these	these	DT
cord-285778-80baxwgc	253	3	barriers	barrier	NNS
cord-285778-80baxwgc	253	4	be	be	VB
cord-285778-80baxwgc	253	5	penetrated	penetrate	VBN
cord-285778-80baxwgc	253	6	,	,	,
cord-285778-80baxwgc	253	7	the	the	DT
cord-285778-80baxwgc	253	8	second	second	JJ
cord-285778-80baxwgc	253	9	,	,	,
cord-285778-80baxwgc	253	10	inducible	inducible	JJ
cord-285778-80baxwgc	253	11	phase	phase	NN
cord-285778-80baxwgc	253	12	of	of	IN
cord-285778-80baxwgc	253	13	innate	innate	JJ
cord-285778-80baxwgc	253	14	defense	defense	NN
cord-285778-80baxwgc	253	15	becomes	become	VBZ
cord-285778-80baxwgc	253	16	effective	effective	JJ
cord-285778-80baxwgc	253	17	4	4	CD
cord-285778-80baxwgc	253	18	-	-	SYM
cord-285778-80baxwgc	253	19	96	96	CD
cord-285778-80baxwgc	253	20	hours	hour	NNS
cord-285778-80baxwgc	253	21	after	after	IN
cord-285778-80baxwgc	253	22	the	the	DT
cord-285778-80baxwgc	253	23	threat	threat	NN
cord-285778-80baxwgc	253	24	enters	enter	VBZ
cord-285778-80baxwgc	253	25	Somatic	somatic	JJ
cord-285778-80baxwgc	253	26	recombination	recombination	NN
cord-285778-80baxwgc	253	27	,	,	,
cord-285778-80baxwgc	253	28	the	the	DT
cord-285778-80baxwgc	253	29	process	process	NN
cord-285778-80baxwgc	253	30	that	that	WDT
cord-285778-80baxwgc	253	31	shuffles	shuffle	VBZ
cord-285778-80baxwgc	253	32	the	the	DT
cord-285778-80baxwgc	253	33	DNA	dna	NN
cord-285778-80baxwgc	253	34	of	of	IN
cord-285778-80baxwgc	253	35	the	the	DT
cord-285778-80baxwgc	253	36	genes	gene	NNS
cord-285778-80baxwgc	253	37	encoding	encode	VBG
cord-285778-80baxwgc	253	38	BCRs	bcr	NNS
cord-285778-80baxwgc	253	39	in	in	IN
cord-285778-80baxwgc	253	40	B	b	NN
cord-285778-80baxwgc	253	41	cells	cell	NNS
cord-285778-80baxwgc	253	42	and	and	CC
cord-285778-80baxwgc	253	43	TCRs	tcr	NNS
cord-285778-80baxwgc	253	44	in	in	IN
cord-285778-80baxwgc	253	45	T	T	NNP
cord-285778-80baxwgc	253	46	cells	cell	NNS
cord-285778-80baxwgc	253	47	,	,	,
cord-285778-80baxwgc	253	48	is	be	VBZ
cord-285778-80baxwgc	253	49	achieved	achieve	VBN
cord-285778-80baxwgc	253	50	by	by	IN
cord-285778-80baxwgc	253	51	specialized	specialized	JJ
cord-285778-80baxwgc	253	52	gen	gen	NNP
cord-285778-80baxwgc	253	53	etic	etic	NNP
cord-285778-80baxwgc	253	54	mechanisms	mechanism	NNS
cord-285778-80baxwgc	253	55	that	that	WDT
cord-285778-80baxwgc	253	56	are	be	VBP
cord-285778-80baxwgc	253	57	des	des	FW
cord-285778-80baxwgc	253	58	cribed	cribed	NNP
cord-285778-80baxwgc	253	59	in	in	IN
cord-285778-80baxwgc	253	60	Chapter	chapter	NN
cord-285778-80baxwgc	253	61	4	4	CD
cord-285778-80baxwgc	253	62	for	for	IN
cord-285778-80baxwgc	253	63	B	b	NN
cord-285778-80baxwgc	253	64	cells	cell	NNS
cord-285778-80baxwgc	253	65	and	and	CC
cord-285778-80baxwgc	253	66	Chapter	chapter	NN
cord-285778-80baxwgc	253	67	8	8	CD
cord-285778-80baxwgc	253	68	for	for	IN
cord-285778-80baxwgc	253	69	T	t	NN
cord-285778-80baxwgc	253	70	cells	cell	NNS
cord-285778-80baxwgc	253	71	.	.	.
cord-285778-80baxwgc	254	1	The	the	DT
cord-285778-80baxwgc	254	2	establishment	establishment	NN
cord-285778-80baxwgc	254	3	of	of	IN
cord-285778-80baxwgc	254	4	central	central	JJ
cord-285778-80baxwgc	254	5	tolerance	tolerance	NN
cord-285778-80baxwgc	254	6	during	during	IN
cord-285778-80baxwgc	254	7	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	254	8	development	development	NN
cord-285778-80baxwgc	254	9	is	be	VBZ
cord-285778-80baxwgc	254	10	described	describe	VBN
cord-285778-80baxwgc	254	11	in	in	IN
cord-285778-80baxwgc	254	12	Chapter	chapter	NN
cord-285778-80baxwgc	254	13	5	5	CD
cord-285778-80baxwgc	254	14	for	for	IN
cord-285778-80baxwgc	254	15	B	b	NN
cord-285778-80baxwgc	254	16	cells	cell	NNS
cord-285778-80baxwgc	254	17	and	and	CC
cord-285778-80baxwgc	254	18	in	in	IN
cord-285778-80baxwgc	254	19	Chapter	chapter	NN
cord-285778-80baxwgc	254	20	9	9	CD
cord-285778-80baxwgc	254	21	for	for	IN
cord-285778-80baxwgc	254	22	T	t	NN
cord-285778-80baxwgc	254	23	cells	cell	NNS
cord-285778-80baxwgc	254	24	.	.	.
cord-285778-80baxwgc	255	1	Processes	process	NNS
cord-285778-80baxwgc	255	2	regulating	regulate	VBG
cord-285778-80baxwgc	255	3	mature	mature	JJ
cord-285778-80baxwgc	255	4	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	255	5	,	,	,
cord-285778-80baxwgc	255	6	including	include	VBG
cord-285778-80baxwgc	255	7	mechanisms	mechanism	NNS
cord-285778-80baxwgc	255	8	of	of	IN
cord-285778-80baxwgc	255	9	peripheral	peripheral	JJ
cord-285778-80baxwgc	255	10	tolerance	tolerance	NN
cord-285778-80baxwgc	255	11	,	,	,
cord-285778-80baxwgc	255	12	are	be	VBP
cord-285778-80baxwgc	255	13	des	des	FW
cord-285778-80baxwgc	255	14	cribed	cribed	NNP
cord-285778-80baxwgc	255	15	in	in	IN
cord-285778-80baxwgc	255	16	Chapter	Chapter	NNP
cord-285778-80baxwgc	255	17	10	10	CD
cord-285778-80baxwgc	255	18	.	.	.
cord-285778-80baxwgc	256	1	A	a	DT
cord-285778-80baxwgc	256	2	pathogen	pathogen	NN
cord-285778-80baxwgc	256	3	attempting	attempt	VBG
cord-285778-80baxwgc	256	4	to	to	TO
cord-285778-80baxwgc	256	5	enter	enter	VB
cord-285778-80baxwgc	256	6	the	the	DT
cord-285778-80baxwgc	256	7	body	body	NN
cord-285778-80baxwgc	256	8	first	first	RB
cord-285778-80baxwgc	256	9	encounters	encounter	VBZ
cord-285778-80baxwgc	256	10	pre	pre	JJ
cord-285778-80baxwgc	256	11	-	-	JJ
cord-285778-80baxwgc	256	12	existing	existing	JJ
cord-285778-80baxwgc	256	13	barriers	barrier	NNS
cord-285778-80baxwgc	256	14	and	and	CC
cord-285778-80baxwgc	256	15	enzymes	enzyme	NNS
cord-285778-80baxwgc	256	16	that	that	WDT
cord-285778-80baxwgc	256	17	block	block	VBP
cord-285778-80baxwgc	256	18	access	access	NN
cord-285778-80baxwgc	256	19	non	non	NNS
cord-285778-80baxwgc	256	20	-	-	NN
cord-285778-80baxwgc	256	21	specifically	specifically	RB
cord-285778-80baxwgc	256	22	.	.	.
cord-285778-80baxwgc	257	1	If	if	IN
cord-285778-80baxwgc	257	2	the	the	DT
cord-285778-80baxwgc	257	3	pathogen	pathogen	NN
cord-285778-80baxwgc	257	4	manages	manage	VBZ
cord-285778-80baxwgc	257	5	to	to	TO
cord-285778-80baxwgc	257	6	enter	enter	VB
cord-285778-80baxwgc	257	7	the	the	DT
cord-285778-80baxwgc	257	8	underlying	underlying	JJ
cord-285778-80baxwgc	257	9	cell	cell	NN
cord-285778-80baxwgc	257	10	layer	layer	NN
cord-285778-80baxwgc	257	11	,	,	,
cord-285778-80baxwgc	257	12	mechanisms	mechanism	NNS
cord-285778-80baxwgc	257	13	mediated	mediate	VBN
cord-285778-80baxwgc	257	14	by	by	IN
cord-285778-80baxwgc	257	15	complement	complement	NN
cord-285778-80baxwgc	257	16	and	and	CC
cord-285778-80baxwgc	257	17	innate	innate	JJ
cord-285778-80baxwgc	257	18	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	257	19	are	be	VBP
cord-285778-80baxwgc	257	20	induced	induce	VBN
cord-285778-80baxwgc	257	21	due	due	IN
cord-285778-80baxwgc	257	22	to	to	IN
cord-285778-80baxwgc	257	23	relatively	relatively	RB
cord-285778-80baxwgc	257	24	broad	broad	JJ
cord-285778-80baxwgc	257	25	recognition	recognition	NN
cord-285778-80baxwgc	257	26	of	of	IN
cord-285778-80baxwgc	257	27	PAMPs	pamp	NNS
cord-285778-80baxwgc	257	28	.	.	.
cord-285778-80baxwgc	258	1	If	if	IN
cord-285778-80baxwgc	258	2	a	a	DT
cord-285778-80baxwgc	258	3	more	more	RBR
cord-285778-80baxwgc	258	4	targeted	targeted	JJ
cord-285778-80baxwgc	258	5	,	,	,
cord-285778-80baxwgc	258	6	pathogen	pathogen	NN
cord-285778-80baxwgc	258	7	-	-	HYPH
cord-285778-80baxwgc	258	8	specific	specific	JJ
cord-285778-80baxwgc	258	9	response	response	NN
cord-285778-80baxwgc	258	10	becomes	become	VBZ
cord-285778-80baxwgc	258	11	necessary	necessary	JJ
cord-285778-80baxwgc	258	12	,	,	,
cord-285778-80baxwgc	258	13	elements	element	NNS
cord-285778-80baxwgc	258	14	of	of	IN
cord-285778-80baxwgc	258	15	innate	innate	JJ
cord-285778-80baxwgc	258	16	immunity	immunity	NN
cord-285778-80baxwgc	258	17	then	then	RB
cord-285778-80baxwgc	258	18	facilitate	facilitate	VB
cord-285778-80baxwgc	258	19	induction	induction	NN
cord-285778-80baxwgc	258	20	of	of	IN
cord-285778-80baxwgc	258	21	highly	highly	RB
cord-285778-80baxwgc	258	22	specific	specific	JJ
cord-285778-80baxwgc	258	23	adaptive	adaptive	JJ
cord-285778-80baxwgc	258	24	responses	response	NNS
cord-285778-80baxwgc	258	25	initiated	initiate	VBN
cord-285778-80baxwgc	258	26	by	by	IN
cord-285778-80baxwgc	258	27	engagement	engagement	NN
cord-285778-80baxwgc	258	28	of	of	IN
cord-285778-80baxwgc	258	29	the	the	DT
cord-285778-80baxwgc	258	30	antigen	antigen	NN
cord-285778-80baxwgc	258	31	receptors	receptor	NNS
cord-285778-80baxwgc	258	32	of	of	IN
cord-285778-80baxwgc	258	33	B	b	NN
cord-285778-80baxwgc	258	34	,	,	,
cord-285778-80baxwgc	258	35	Th	Th	NNP
cord-285778-80baxwgc	258	36	or	or	CC
cord-285778-80baxwgc	258	37	Tc	Tc	NNP
cord-285778-80baxwgc	258	38	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	258	39	.	.	.
cord-285778-80baxwgc	259	1	Complement	complement	JJ
cord-285778-80baxwgc	259	2	activation	activation	NN
cord-285778-80baxwgc	259	3	Phagocytosis	Phagocytosis	NNP
cord-285778-80baxwgc	259	4	Target	Target	NNP
cord-285778-80baxwgc	259	5	cell	cell	NN
cord-285778-80baxwgc	259	6	lysis	lysis	NN
cord-285778-80baxwgc	259	7	Inflammation	inflammation	NN
cord-285778-80baxwgc	259	8	Skin	skin	NN
cord-285778-80baxwgc	259	9	Mucosal	Mucosal	NNP
cord-285778-80baxwgc	259	10	barrier	barrier	NN
cord-285778-80baxwgc	259	11	pH	ph	NN
cord-285778-80baxwgc	259	12	,	,	,
cord-285778-80baxwgc	259	13	saliva	saliva	NN
cord-285778-80baxwgc	259	14	,	,	,
cord-285778-80baxwgc	259	15	proteases	protease	NNS
cord-285778-80baxwgc	259	16	,	,	,
cord-285778-80baxwgc	259	17	etc	etc	FW
cord-285778-80baxwgc	259	18	.	.	.
cord-285778-80baxwgc	260	1	the	the	DT
cord-285778-80baxwgc	260	2	body	body	NN
cord-285778-80baxwgc	260	3	.	.	.
cord-285778-80baxwgc	261	1	Innate	innate	JJ
cord-285778-80baxwgc	261	2	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	261	3	activated	activate	VBN
cord-285778-80baxwgc	261	4	by	by	IN
cord-285778-80baxwgc	261	5	the	the	DT
cord-285778-80baxwgc	261	6	binding	binding	NN
cord-285778-80baxwgc	261	7	of	of	IN
cord-285778-80baxwgc	261	8	PRRs	prr	NNS
cord-285778-80baxwgc	261	9	to	to	IN
cord-285778-80baxwgc	261	10	PAMPs	pamp	NNS
cord-285778-80baxwgc	261	11	provided	provide	VBN
cord-285778-80baxwgc	261	12	by	by	IN
cord-285778-80baxwgc	261	13	the	the	DT
cord-285778-80baxwgc	261	14	attacking	attack	VBG
cord-285778-80baxwgc	261	15	pathogen	pathogen	NN
cord-285778-80baxwgc	261	16	,	,	,
cord-285778-80baxwgc	261	17	or	or	CC
cord-285778-80baxwgc	261	18	to	to	TO
cord-285778-80baxwgc	261	19	DAMPs	damps	VB
cord-285778-80baxwgc	261	20	present	present	JJ
cord-285778-80baxwgc	261	21	due	due	IN
cord-285778-80baxwgc	261	22	to	to	TO
cord-285778-80baxwgc	261	23	host	host	VB
cord-285778-80baxwgc	261	24	cell	cell	NN
cord-285778-80baxwgc	261	25	injury	injury	NN
cord-285778-80baxwgc	261	26	or	or	CC
cord-285778-80baxwgc	261	27	death	death	NN
cord-285778-80baxwgc	261	28	,	,	,
cord-285778-80baxwgc	261	29	work	work	VBP
cord-285778-80baxwgc	261	30	quickly	quickly	RB
cord-285778-80baxwgc	261	31	to	to	TO
cord-285778-80baxwgc	261	32	eliminate	eliminate	VB
cord-285778-80baxwgc	261	33	the	the	DT
cord-285778-80baxwgc	261	34	invader	invader	NN
cord-285778-80baxwgc	261	35	using	use	VBG
cord-285778-80baxwgc	261	36	the	the	DT
cord-285778-80baxwgc	261	37	mechanisms	mechanism	NNS
cord-285778-80baxwgc	261	38	of	of	IN
cord-285778-80baxwgc	261	39	inflammation	inflammation	NN
cord-285778-80baxwgc	261	40	,	,	,
cord-285778-80baxwgc	261	41	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	261	42	and	and	CC
cord-285778-80baxwgc	261	43	target	target	NN
cord-285778-80baxwgc	261	44	cell	cell	NN
cord-285778-80baxwgc	261	45	lysis	lysis	NN
cord-285778-80baxwgc	261	46	.	.	.
cord-285778-80baxwgc	262	1	Complement	complement	JJ
cord-285778-80baxwgc	262	2	activation	activation	NN
cord-285778-80baxwgc	262	3	also	also	RB
cord-285778-80baxwgc	262	4	contributes	contribute	VBZ
cord-285778-80baxwgc	262	5	to	to	IN
cord-285778-80baxwgc	262	6	clearance	clearance	NN
cord-285778-80baxwgc	262	7	at	at	IN
cord-285778-80baxwgc	262	8	this	this	DT
cord-285778-80baxwgc	262	9	stage	stage	NN
cord-285778-80baxwgc	262	10	.	.	.
cord-285778-80baxwgc	263	1	In	in	IN
cord-285778-80baxwgc	263	2	many	many	JJ
cord-285778-80baxwgc	263	3	cases	case	NNS
cord-285778-80baxwgc	263	4	,	,	,
cord-285778-80baxwgc	263	5	the	the	DT
cord-285778-80baxwgc	263	6	incursion	incursion	NN
cord-285778-80baxwgc	263	7	is	be	VBZ
cord-285778-80baxwgc	263	8	completely	completely	RB
cord-285778-80baxwgc	263	9	controlled	control	VBN
cord-285778-80baxwgc	263	10	by	by	IN
cord-285778-80baxwgc	263	11	the	the	DT
cord-285778-80baxwgc	263	12	two	two	CD
cord-285778-80baxwgc	263	13	phases	phase	NNS
cord-285778-80baxwgc	263	14	of	of	IN
cord-285778-80baxwgc	263	15	innate	innate	JJ
cord-285778-80baxwgc	263	16	defense	defense	NN
cord-285778-80baxwgc	263	17	before	before	IN
cord-285778-80baxwgc	263	18	adaptive	adaptive	JJ
cord-285778-80baxwgc	263	19	immunity	immunity	NN
cord-285778-80baxwgc	263	20	is	be	VBZ
cord-285778-80baxwgc	263	21	even	even	RB
cord-285778-80baxwgc	263	22	triggered	trigger	VBN
cord-285778-80baxwgc	263	23	.	.	.
cord-285778-80baxwgc	264	1	However	however	RB
cord-285778-80baxwgc	264	2	,	,	,
cord-285778-80baxwgc	264	3	the	the	DT
cord-285778-80baxwgc	264	4	cells	cell	NNS
cord-285778-80baxwgc	264	5	of	of	IN
cord-285778-80baxwgc	264	6	the	the	DT
cord-285778-80baxwgc	264	7	innate	innate	JJ
cord-285778-80baxwgc	264	8	response	response	NN
cord-285778-80baxwgc	264	9	are	be	VBP
cord-285778-80baxwgc	264	10	ultimately	ultimately	RB
cord-285778-80baxwgc	264	11	limited	limit	VBN
cord-285778-80baxwgc	264	12	both	both	CC
cord-285778-80baxwgc	264	13	in	in	IN
cord-285778-80baxwgc	264	14	numbers	number	NNS
cord-285778-80baxwgc	264	15	and	and	CC
cord-285778-80baxwgc	264	16	in	in	IN
cord-285778-80baxwgc	264	17	recognition	recognition	NN
cord-285778-80baxwgc	264	18	capacity	capacity	NN
cord-285778-80baxwgc	264	19	.	.	.
cord-285778-80baxwgc	265	1	Fortunately	fortunately	RB
cord-285778-80baxwgc	265	2	,	,	,
cord-285778-80baxwgc	265	3	even	even	RB
cord-285778-80baxwgc	265	4	if	if	IN
cord-285778-80baxwgc	265	5	the	the	DT
cord-285778-80baxwgc	265	6	pathogen	pathogen	NN
cord-285778-80baxwgc	265	7	ultimately	ultimately	RB
cord-285778-80baxwgc	265	8	manages	manage	VBZ
cord-285778-80baxwgc	265	9	to	to	TO
cord-285778-80baxwgc	265	10	thwart	thwart	VB
cord-285778-80baxwgc	265	11	complete	complete	JJ
cord-285778-80baxwgc	265	12	elimination	elimination	NN
cord-285778-80baxwgc	265	13	by	by	IN
cord-285778-80baxwgc	265	14	innate	innate	JJ
cord-285778-80baxwgc	265	15	immunity	immunity	NN
cord-285778-80baxwgc	265	16	,	,	,
cord-285778-80baxwgc	265	17	some	some	DT
cord-285778-80baxwgc	265	18	of	of	IN
cord-285778-80baxwgc	265	19	the	the	DT
cord-285778-80baxwgc	265	20	invaders	invader	NNS
cord-285778-80baxwgc	265	21	and/or	and/or	CC
cord-285778-80baxwgc	266	1	their	-PRON-	PRP$
cord-285778-80baxwgc	266	2	components	component	NNS
cord-285778-80baxwgc	266	3	or	or	CC
cord-285778-80baxwgc	266	4	products	product	NNS
cord-285778-80baxwgc	266	5	will	will	MD
cord-285778-80baxwgc	266	6	have	have	VB
cord-285778-80baxwgc	266	7	been	be	VBN
cord-285778-80baxwgc	266	8	taken	take	VBN
cord-285778-80baxwgc	266	9	up	up	RP
cord-285778-80baxwgc	266	10	by	by	IN
cord-285778-80baxwgc	266	11	innate	innate	JJ
cord-285778-80baxwgc	266	12	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	266	13	and	and	CC
cord-285778-80baxwgc	266	14	presented	present	VBN
cord-285778-80baxwgc	266	15	as	as	IN
cord-285778-80baxwgc	266	16	foreign	foreign	JJ
cord-285778-80baxwgc	266	17	antigens	antigen	NNS
cord-285778-80baxwgc	266	18	to	to	IN
cord-285778-80baxwgc	266	19	T	T	NNP
cord-285778-80baxwgc	266	20	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	266	21	.	.	.
cord-285778-80baxwgc	267	1	The	the	DT
cord-285778-80baxwgc	267	2	third	third	JJ
cord-285778-80baxwgc	267	3	and	and	CC
cord-285778-80baxwgc	267	4	final	final	JJ
cord-285778-80baxwgc	267	5	phase	phase	NN
cord-285778-80baxwgc	267	6	of	of	IN
cord-285778-80baxwgc	267	7	host	host	NN
cord-285778-80baxwgc	267	8	defense	defense	NN
cord-285778-80baxwgc	267	9	mediated	mediate	VBN
cord-285778-80baxwgc	267	10	by	by	IN
cord-285778-80baxwgc	267	11	adaptive	adaptive	JJ
cord-285778-80baxwgc	267	12	immunity	immunity	NN
cord-285778-80baxwgc	267	13	is	be	VBZ
cord-285778-80baxwgc	267	14	thus	thus	RB
cord-285778-80baxwgc	267	15	initiated	initiate	VBN
cord-285778-80baxwgc	267	16	.	.	.
cord-285778-80baxwgc	268	1	Th	th	RB
cord-285778-80baxwgc	268	2	,	,	,
cord-285778-80baxwgc	268	3	Tc	Tc	NNP
cord-285778-80baxwgc	268	4	and	and	CC
cord-285778-80baxwgc	268	5	B	B	NNP
cord-285778-80baxwgc	268	6	cells	cell	NNS
cord-285778-80baxwgc	268	7	are	be	VBP
cord-285778-80baxwgc	268	8	clonally	clonally	RB
cord-285778-80baxwgc	268	9	selected	select	VBN
cord-285778-80baxwgc	268	10	and	and	CC
cord-285778-80baxwgc	268	11	activated	activate	VBN
cord-285778-80baxwgc	268	12	,	,	,
cord-285778-80baxwgc	268	13	and	and	CC
cord-285778-80baxwgc	268	14	then	then	RB
cord-285778-80baxwgc	268	15	proliferate	proliferate	VB
cord-285778-80baxwgc	268	16	and	and	CC
cord-285778-80baxwgc	268	17	differentiate	differentiate	VB
cord-285778-80baxwgc	268	18	into	into	IN
cord-285778-80baxwgc	268	19	memory	memory	NN
cord-285778-80baxwgc	268	20	cells	cell	NNS
cord-285778-80baxwgc	268	21	and	and	CC
cord-285778-80baxwgc	268	22	large	large	JJ
cord-285778-80baxwgc	268	23	numbers	number	NNS
cord-285778-80baxwgc	268	24	of	of	IN
cord-285778-80baxwgc	268	25	daughter	daughter	NN
cord-285778-80baxwgc	268	26	effector	effector	NN
cord-285778-80baxwgc	268	27	cells	cell	NNS
cord-285778-80baxwgc	268	28	that	that	WDT
cord-285778-80baxwgc	268	29	eliminate	eliminate	VBP
cord-285778-80baxwgc	268	30	the	the	DT
cord-285778-80baxwgc	268	31	pathogen	pathogen	NN
cord-285778-80baxwgc	268	32	via	via	IN
cord-285778-80baxwgc	268	33	humoral	humoral	JJ
cord-285778-80baxwgc	268	34	and/or	and/or	CC
cord-285778-80baxwgc	268	35	cell	cell	NN
cord-285778-80baxwgc	268	36	-	-	HYPH
cord-285778-80baxwgc	268	37	mediated	mediate	VBN
cord-285778-80baxwgc	268	38	mechanisms	mechanism	NNS
cord-285778-80baxwgc	268	39	.	.	.
cord-285778-80baxwgc	269	1	Because	because	IN
cord-285778-80baxwgc	269	2	it	-PRON-	PRP
cord-285778-80baxwgc	269	3	takes	take	VBZ
cord-285778-80baxwgc	269	4	time	time	NN
cord-285778-80baxwgc	269	5	for	for	IN
cord-285778-80baxwgc	269	6	the	the	DT
cord-285778-80baxwgc	269	7	clonally	clonally	RB
cord-285778-80baxwgc	269	8	selected	select	VBN
cord-285778-80baxwgc	269	9	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	269	10	to	to	TO
cord-285778-80baxwgc	269	11	produce	produce	VB
cord-285778-80baxwgc	269	12	effector	effector	NN
cord-285778-80baxwgc	269	13	cells	cell	NNS
cord-285778-80baxwgc	269	14	,	,	,
cord-285778-80baxwgc	269	15	adaptive	adaptive	JJ
cord-285778-80baxwgc	269	16	responses	response	NNS
cord-285778-80baxwgc	269	17	are	be	VBP
cord-285778-80baxwgc	269	18	not	not	RB
cord-285778-80baxwgc	269	19	usually	usually	RB
cord-285778-80baxwgc	269	20	observed	observe	VBN
cord-285778-80baxwgc	269	21	until	until	IN
cord-285778-80baxwgc	269	22	at	at	RB
cord-285778-80baxwgc	269	23	least	least	RBS
cord-285778-80baxwgc	269	24	96	96	CD
cord-285778-80baxwgc	269	25	hours	hour	NNS
cord-285778-80baxwgc	269	26	after	after	IN
cord-285778-80baxwgc	269	27	the	the	DT
cord-285778-80baxwgc	269	28	start	start	NN
cord-285778-80baxwgc	269	29	of	of	IN
cord-285778-80baxwgc	269	30	infection	infection	NN
cord-285778-80baxwgc	269	31	.	.	.
cord-285778-80baxwgc	270	1	The	the	DT
cord-285778-80baxwgc	270	2	second	second	JJ
cord-285778-80baxwgc	270	3	and	and	CC
cord-285778-80baxwgc	270	4	third	third	JJ
cord-285778-80baxwgc	270	5	phases	phase	NNS
cord-285778-80baxwgc	270	6	of	of	IN
cord-285778-80baxwgc	270	7	immune	immune	JJ
cord-285778-80baxwgc	270	8	defense	defense	NN
cord-285778-80baxwgc	270	9	are	be	VBP
cord-285778-80baxwgc	270	10	more	more	RBR
cord-285778-80baxwgc	270	11	tightly	tightly	RB
cord-285778-80baxwgc	270	12	interwoven	interwoven	JJ
cord-285778-80baxwgc	270	13	than	than	IN
cord-285778-80baxwgc	270	14	it	-PRON-	PRP
cord-285778-80baxwgc	270	15	may	may	MD
cord-285778-80baxwgc	270	16	first	first	RB
cord-285778-80baxwgc	270	17	appear	appear	VB
cord-285778-80baxwgc	270	18	.	.	.
cord-285778-80baxwgc	271	1	Innate	innate	JJ
cord-285778-80baxwgc	271	2	and	and	CC
cord-285778-80baxwgc	271	3	adaptive	adaptive	JJ
cord-285778-80baxwgc	271	4	immunity	immunity	NN
cord-285778-80baxwgc	271	5	do	do	VBP
cord-285778-80baxwgc	271	6	not	not	RB
cord-285778-80baxwgc	271	7	operate	operate	VB
cord-285778-80baxwgc	271	8	in	in	IN
cord-285778-80baxwgc	271	9	isolation	isolation	NN
cord-285778-80baxwgc	271	10	,	,	,
cord-285778-80baxwgc	271	11	and	and	CC
cord-285778-80baxwgc	271	12	each	each	DT
cord-285778-80baxwgc	271	13	depends	depend	VBZ
cord-285778-80baxwgc	271	14	on	on	IN
cord-285778-80baxwgc	271	15	or	or	CC
cord-285778-80baxwgc	271	16	is	be	VBZ
cord-285778-80baxwgc	271	17	enhanced	enhance	VBN
cord-285778-80baxwgc	271	18	by	by	IN
cord-285778-80baxwgc	271	19	elements	element	NNS
cord-285778-80baxwgc	271	20	of	of	IN
cord-285778-80baxwgc	271	21	the	the	DT
cord-285778-80baxwgc	271	22	other	other	JJ
cord-285778-80baxwgc	271	23	(	(	-LRB-
cord-285778-80baxwgc	271	24	Fig	Fig	NNP
cord-285778-80baxwgc	271	25	.	.	.
cord-285778-80baxwgc	271	26	1	1	CD
cord-285778-80baxwgc	271	27	-	-	SYM
cord-285778-80baxwgc	271	28	8	8	CD
cord-285778-80baxwgc	271	29	)	)	-RRB-
cord-285778-80baxwgc	271	30	.	.	.
cord-285778-80baxwgc	272	1	The	the	DT
cord-285778-80baxwgc	272	2	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	272	3	of	of	IN
cord-285778-80baxwgc	272	4	the	the	DT
cord-285778-80baxwgc	272	5	adaptive	adaptive	JJ
cord-285778-80baxwgc	272	6	response	response	NN
cord-285778-80baxwgc	272	7	require	require	VBP
cord-285778-80baxwgc	272	8	the	the	DT
cord-285778-80baxwgc	272	9	involvement	involvement	NN
cord-285778-80baxwgc	272	10	of	of	IN
cord-285778-80baxwgc	272	11	cells	cell	NNS
cord-285778-80baxwgc	272	12	and	and	CC
cord-285778-80baxwgc	272	13	cytokines	cytokine	NNS
cord-285778-80baxwgc	272	14	of	of	IN
cord-285778-80baxwgc	272	15	the	the	DT
cord-285778-80baxwgc	272	16	innate	innate	JJ
cord-285778-80baxwgc	272	17	system	system	NN
cord-285778-80baxwgc	272	18	to	to	TO
cord-285778-80baxwgc	272	19	become	become	VB
cord-285778-80baxwgc	272	20	activated	activate	VBN
cord-285778-80baxwgc	272	21	and	and	CC
cord-285778-80baxwgc	272	22	undergo	undergo	VB
cord-285778-80baxwgc	272	23	differentiation	differentiation	NN
cord-285778-80baxwgc	272	24	into	into	IN
cord-285778-80baxwgc	272	25	effector	effector	NN
cord-285778-80baxwgc	272	26	and	and	CC
cord-285778-80baxwgc	272	27	memory	memory	NN
cord-285778-80baxwgc	272	28	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	272	29	.	.	.
cord-285778-80baxwgc	273	1	Conversely	conversely	RB
cord-285778-80baxwgc	273	2	,	,	,
cord-285778-80baxwgc	273	3	activated	activate	VBN
cord-285778-80baxwgc	273	4	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	273	5	secrete	secrete	JJ
cord-285778-80baxwgc	273	6	products	product	NNS
cord-285778-80baxwgc	273	7	that	that	WDT
cord-285778-80baxwgc	273	8	stimulate	stimulate	VBP
cord-285778-80baxwgc	273	9	and	and	CC
cord-285778-80baxwgc	273	10	improve	improve	VB
cord-285778-80baxwgc	273	11	the	the	DT
cord-285778-80baxwgc	273	12	effectiveness	effectiveness	NN
cord-285778-80baxwgc	273	13	of	of	IN
cord-285778-80baxwgc	273	14	innate	innate	JJ
cord-285778-80baxwgc	273	15	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	273	16	.	.	.
cord-285778-80baxwgc	274	1	The	the	DT
cord-285778-80baxwgc	274	2	interplay	interplay	NN
cord-285778-80baxwgc	274	3	between	between	IN
cord-285778-80baxwgc	274	4	innate	innate	JJ
cord-285778-80baxwgc	274	5	and	and	CC
cord-285778-80baxwgc	274	6	adaptive	adaptive	JJ
cord-285778-80baxwgc	274	7	immunity	immunity	NN
cord-285778-80baxwgc	274	8	is	be	VBZ
cord-285778-80baxwgc	274	9	sustained	sustain	VBN
cord-285778-80baxwgc	274	10	by	by	IN
cord-285778-80baxwgc	274	11	cytokine	cytokine	NN
cord-285778-80baxwgc	274	12	signaling	signaling	NN
cord-285778-80baxwgc	274	13	and	and	CC
cord-285778-80baxwgc	274	14	through	through	IN
cord-285778-80baxwgc	274	15	direct	direct	JJ
cord-285778-80baxwgc	274	16	intercellular	intercellular	JJ
cord-285778-80baxwgc	274	17	contacts	contact	NNS
cord-285778-80baxwgc	274	18	between	between	IN
cord-285778-80baxwgc	274	19	innate	innate	JJ
cord-285778-80baxwgc	274	20	and	and	CC
cord-285778-80baxwgc	274	21	adaptive	adaptive	JJ
cord-285778-80baxwgc	274	22	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	274	23	.	.	.
cord-285778-80baxwgc	275	1	By	by	IN
cord-285778-80baxwgc	275	2	cooperating	cooperate	VBG
cord-285778-80baxwgc	275	3	in	in	IN
cord-285778-80baxwgc	275	4	this	this	DT
cord-285778-80baxwgc	275	5	way	way	NN
cord-285778-80baxwgc	275	6	,	,	,
cord-285778-80baxwgc	275	7	innate	innate	JJ
cord-285778-80baxwgc	275	8	and	and	CC
cord-285778-80baxwgc	275	9	adaptive	adaptive	JJ
cord-285778-80baxwgc	275	10	immunity	immunity	NN
cord-285778-80baxwgc	275	11	combine	combine	NN
cord-285778-80baxwgc	275	12	to	to	TO
cord-285778-80baxwgc	275	13	mount	mount	VB
cord-285778-80baxwgc	275	14	an	an	DT
cord-285778-80baxwgc	275	15	optimal	optimal	JJ
cord-285778-80baxwgc	275	16	defense	defense	NN
cord-285778-80baxwgc	275	17	against	against	IN
cord-285778-80baxwgc	275	18	pathogens	pathogen	NNS
cord-285778-80baxwgc	275	19	.	.	.
cord-285778-80baxwgc	276	1	Normal	normal	JJ
cord-285778-80baxwgc	276	2	host	host	NN
cord-285778-80baxwgc	276	3	homeostasis	homeostasis	NN
cord-285778-80baxwgc	276	4	is	be	VBZ
cord-285778-80baxwgc	276	5	re	re	VBG
cord-285778-80baxwgc	276	6	-	-	VBN
cord-285778-80baxwgc	276	7	established	establish	VBN
cord-285778-80baxwgc	276	8	when	when	WRB
cord-285778-80baxwgc	276	9	the	the	DT
cord-285778-80baxwgc	276	10	host	host	NN
cord-285778-80baxwgc	276	11	wins	win	VBZ
cord-285778-80baxwgc	276	12	(	(	-LRB-
cord-285778-80baxwgc	276	13	at	at	IN
cord-285778-80baxwgc	276	14	least	least	JJS
cord-285778-80baxwgc	276	15	for	for	IN
cord-285778-80baxwgc	276	16	that	that	DT
cord-285778-80baxwgc	276	17	moment	moment	NN
cord-285778-80baxwgc	276	18	)	)	-RRB-
cord-285778-80baxwgc	277	1	the	the	DT
cord-285778-80baxwgc	277	2	ongoing	ongoing	JJ
cord-285778-80baxwgc	277	3	horse	horse	NN
cord-285778-80baxwgc	277	4	race	race	NN
cord-285778-80baxwgc	277	5	between	between	IN
cord-285778-80baxwgc	277	6	the	the	DT
cord-285778-80baxwgc	277	7	host	host	NN
cord-285778-80baxwgc	277	8	's	's	POS
cord-285778-80baxwgc	277	9	immune	immune	JJ
cord-285778-80baxwgc	277	10	system	system	NN
cord-285778-80baxwgc	277	11	and	and	CC
cord-285778-80baxwgc	277	12	a	a	DT
cord-285778-80baxwgc	277	13	pathogen	pathogen	NN
cord-285778-80baxwgc	277	14	attempting	attempt	VBG
cord-285778-80baxwgc	277	15	to	to	TO
cord-285778-80baxwgc	277	16	establish	establish	VB
cord-285778-80baxwgc	277	17	infection	infection	NN
cord-285778-80baxwgc	277	18	.	.	.
cord-285778-80baxwgc	278	1	Pathogens	pathogen	NNS
cord-285778-80baxwgc	278	2	replicate	replicate	VBP
cord-285778-80baxwgc	278	3	at	at	IN
cord-285778-80baxwgc	278	4	widely	widely	RB
cord-285778-80baxwgc	278	5	divergent	divergent	JJ
cord-285778-80baxwgc	278	6	rates	rate	NNS
cord-285778-80baxwgc	278	7	,	,	,
cord-285778-80baxwgc	278	8	with	with	IN
cord-285778-80baxwgc	278	9	some	some	DT
cord-285778-80baxwgc	278	10	bacteria	bacteria	NNS
cord-285778-80baxwgc	278	11	and	and	CC
cord-285778-80baxwgc	278	12	viruses	virus	NNS
cord-285778-80baxwgc	278	13	able	able	JJ
cord-285778-80baxwgc	278	14	to	to	TO
cord-285778-80baxwgc	278	15	double	double	VB
cord-285778-80baxwgc	278	16	their	-PRON-	PRP$
cord-285778-80baxwgc	278	17	population	population	NN
cord-285778-80baxwgc	278	18	size	size	NN
cord-285778-80baxwgc	278	19	within	within	IN
cord-285778-80baxwgc	278	20	a	a	DT
cord-285778-80baxwgc	278	21	couple	couple	NN
cord-285778-80baxwgc	278	22	of	of	IN
cord-285778-80baxwgc	278	23	hours	hour	NNS
cord-285778-80baxwgc	278	24	.	.	.
cord-285778-80baxwgc	279	1	Fast	fast	RB
cord-285778-80baxwgc	279	2	-	-	HYPH
cord-285778-80baxwgc	279	3	replicating	replicate	VBG
cord-285778-80baxwgc	279	4	pathogens	pathogen	NNS
cord-285778-80baxwgc	279	5	therefore	therefore	RB
cord-285778-80baxwgc	279	6	initially	initially	RB
cord-285778-80baxwgc	279	7	get	get	VBP
cord-285778-80baxwgc	279	8	ahead	ahead	RB
cord-285778-80baxwgc	279	9	of	of	IN
cord-285778-80baxwgc	279	10	the	the	DT
cord-285778-80baxwgc	279	11	host	host	NN
cord-285778-80baxwgc	279	12	's	's	POS
cord-285778-80baxwgc	279	13	immune	immune	JJ
cord-285778-80baxwgc	279	14	defenses	defense	NNS
cord-285778-80baxwgc	279	15	,	,	,
cord-285778-80baxwgc	279	16	but	but	CC
cord-285778-80baxwgc	279	17	then	then	RB
cord-285778-80baxwgc	279	18	are	be	VBP
cord-285778-80baxwgc	279	19	caught	catch	VBN
cord-285778-80baxwgc	279	20	and	and	CC
cord-285778-80baxwgc	279	21	destroyed	destroy	VBN
cord-285778-80baxwgc	279	22	as	as	IN
cord-285778-80baxwgc	279	23	the	the	DT
cord-285778-80baxwgc	279	24	specialized	specialized	JJ
cord-285778-80baxwgc	279	25	cells	cell	NNS
cord-285778-80baxwgc	279	26	of	of	IN
cord-285778-80baxwgc	279	27	the	the	DT
cord-285778-80baxwgc	279	28	immune	immune	JJ
cord-285778-80baxwgc	279	29	system	system	NN
cord-285778-80baxwgc	279	30	become	become	VBP
cord-285778-80baxwgc	279	31	activated	activate	VBN
cord-285778-80baxwgc	279	32	.	.	.
cord-285778-80baxwgc	280	1	The	the	DT
cord-285778-80baxwgc	280	2	mystery	mystery	NN
cord-285778-80baxwgc	280	3	highlighted	highlight	VBN
cord-285778-80baxwgc	280	4	by	by	IN
cord-285778-80baxwgc	280	5	the	the	DT
cord-285778-80baxwgc	280	6	authors	author	NNS
cord-285778-80baxwgc	280	7	of	of	IN
cord-285778-80baxwgc	280	8	this	this	DT
cord-285778-80baxwgc	280	9	article	article	NN
cord-285778-80baxwgc	280	10	is	be	VBZ
cord-285778-80baxwgc	280	11	why	why	WRB
cord-285778-80baxwgc	280	12	slowreplicating	slowreplicating	NN
cord-285778-80baxwgc	280	13	pathogens	pathogen	NNS
cord-285778-80baxwgc	280	14	are	be	VBP
cord-285778-80baxwgc	280	15	able	able	JJ
cord-285778-80baxwgc	280	16	to	to	TO
cord-285778-80baxwgc	280	17	establish	establish	VB
cord-285778-80baxwgc	280	18	infections	infection	NNS
cord-285778-80baxwgc	280	19	at	at	RB
cord-285778-80baxwgc	280	20	all	all	RB
cord-285778-80baxwgc	280	21	,	,	,
cord-285778-80baxwgc	280	22	and	and	CC
cord-285778-80baxwgc	280	23	why	why	WRB
cord-285778-80baxwgc	280	24	so	so	RB
cord-285778-80baxwgc	280	25	many	many	JJ
cord-285778-80baxwgc	280	26	of	of	IN
cord-285778-80baxwgc	280	27	the	the	DT
cord-285778-80baxwgc	280	28	most	most	RBS
cord-285778-80baxwgc	280	29	damaging	damaging	JJ
cord-285778-80baxwgc	280	30	chronic	chronic	JJ
cord-285778-80baxwgc	280	31	infections	infection	NNS
cord-285778-80baxwgc	280	32	we	-PRON-	PRP
cord-285778-80baxwgc	280	33	experience	experience	VBP
cord-285778-80baxwgc	280	34	,	,	,
cord-285778-80baxwgc	280	35	like	like	IN
cord-285778-80baxwgc	280	36	those	those	DT
cord-285778-80baxwgc	280	37	of	of	IN
cord-285778-80baxwgc	280	38	the	the	DT
cord-285778-80baxwgc	280	39	hepatitis	hepatitis	NN
cord-285778-80baxwgc	280	40	B	B	NNP
cord-285778-80baxwgc	280	41	and	and	CC
cord-285778-80baxwgc	280	42	C	C	NNP
cord-285778-80baxwgc	280	43	viruses	virus	NNS
cord-285778-80baxwgc	280	44	and	and	CC
cord-285778-80baxwgc	280	45	the	the	DT
cord-285778-80baxwgc	280	46	bacteria	bacteria	NNS
cord-285778-80baxwgc	280	47	causing	cause	VBG
cord-285778-80baxwgc	280	48	tuberculosis	tuberculosis	NN
cord-285778-80baxwgc	280	49	,	,	,
cord-285778-80baxwgc	280	50	are	be	VBP
cord-285778-80baxwgc	280	51	caused	cause	VBN
cord-285778-80baxwgc	280	52	by	by	IN
cord-285778-80baxwgc	280	53	some	some	DT
cord-285778-80baxwgc	280	54	of	of	IN
cord-285778-80baxwgc	280	55	the	the	DT
cord-285778-80baxwgc	280	56	slowest	slowest	RBS
cord-285778-80baxwgc	280	57	-	-	HYPH
cord-285778-80baxwgc	280	58	replicating	replicate	VBG
cord-285778-80baxwgc	280	59	pathogens	pathogen	NNS
cord-285778-80baxwgc	280	60	.	.	.
cord-285778-80baxwgc	281	1	The	the	DT
cord-285778-80baxwgc	281	2	answer	answer	NN
cord-285778-80baxwgc	281	3	may	may	MD
cord-285778-80baxwgc	281	4	lie	lie	VB
cord-285778-80baxwgc	281	5	in	in	IN
cord-285778-80baxwgc	281	6	achieving	achieve	VBG
cord-285778-80baxwgc	281	7	certain	certain	JJ
cord-285778-80baxwgc	281	8	threshold	threshold	NN
cord-285778-80baxwgc	281	9	levels	level	NNS
cord-285778-80baxwgc	281	10	of	of	IN
cord-285778-80baxwgc	281	11	infection	infection	NN
cord-285778-80baxwgc	281	12	that	that	WDT
cord-285778-80baxwgc	281	13	supply	supply	VBP
cord-285778-80baxwgc	281	14	adequate	adequate	JJ
cord-285778-80baxwgc	281	15	amounts	amount	NNS
cord-285778-80baxwgc	281	16	of	of	IN
cord-285778-80baxwgc	281	17	the	the	DT
cord-285778-80baxwgc	281	18	molecular	molecular	JJ
cord-285778-80baxwgc	281	19	triggers	trigger	NNS
cord-285778-80baxwgc	281	20	needed	need	VBN
cord-285778-80baxwgc	281	21	to	to	TO
cord-285778-80baxwgc	281	22	spark	spark	VB
cord-285778-80baxwgc	281	23	first	first	RB
cord-285778-80baxwgc	281	24	the	the	DT
cord-285778-80baxwgc	281	25	innate	innate	JJ
cord-285778-80baxwgc	281	26	response	response	NN
cord-285778-80baxwgc	281	27	and	and	CC
cord-285778-80baxwgc	281	28	then	then	RB
cord-285778-80baxwgc	281	29	the	the	DT
cord-285778-80baxwgc	281	30	adaptive	adaptive	JJ
cord-285778-80baxwgc	281	31	response	response	NN
cord-285778-80baxwgc	281	32	.	.	.
cord-285778-80baxwgc	282	1	If	if	IN
cord-285778-80baxwgc	282	2	a	a	DT
cord-285778-80baxwgc	282	3	pathogen	pathogen	NN
cord-285778-80baxwgc	282	4	replicates	replicate	VBZ
cord-285778-80baxwgc	282	5	rapidly	rapidly	RB
cord-285778-80baxwgc	282	6	,	,	,
cord-285778-80baxwgc	282	7	large	large	JJ
cord-285778-80baxwgc	282	8	amounts	amount	NNS
cord-285778-80baxwgc	282	9	of	of	IN
cord-285778-80baxwgc	282	10	DAMPs	damp	NNS
cord-285778-80baxwgc	282	11	and	and	CC
cord-285778-80baxwgc	282	12	PAMPs	pamp	NNS
cord-285778-80baxwgc	282	13	are	be	VBP
cord-285778-80baxwgc	282	14	present	present	JJ
cord-285778-80baxwgc	282	15	that	that	IN
cord-285778-80baxwgc	282	16	immediately	immediately	RB
cord-285778-80baxwgc	282	17	activate	activate	VBP
cord-285778-80baxwgc	282	18	innate	innate	JJ
cord-285778-80baxwgc	282	19	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	282	20	,	,	,
cord-285778-80baxwgc	282	21	including	include	VBG
cord-285778-80baxwgc	282	22	the	the	DT
cord-285778-80baxwgc	282	23	APCs	apc	NNS
cord-285778-80baxwgc	282	24	needed	need	VBN
cord-285778-80baxwgc	282	25	to	to	TO
cord-285778-80baxwgc	282	26	initiate	initiate	VB
cord-285778-80baxwgc	282	27	T	T	NNP
cord-285778-80baxwgc	282	28	cell	cell	NN
cord-285778-80baxwgc	282	29	responses	response	NNS
cord-285778-80baxwgc	282	30	.	.	.
cord-285778-80baxwgc	283	1	These	these	DT
cord-285778-80baxwgc	283	2	T	t	NN
cord-285778-80baxwgc	283	3	cells	cell	NNS
cord-285778-80baxwgc	283	4	proliferate	proliferate	VBP
cord-285778-80baxwgc	283	5	quickly	quickly	RB
cord-285778-80baxwgc	283	6	enough	enough	RB
cord-285778-80baxwgc	283	7	to	to	TO
cord-285778-80baxwgc	283	8	overwhelm	overwhelm	VB
cord-285778-80baxwgc	283	9	the	the	DT
cord-285778-80baxwgc	283	10	pathogen	pathogen	NN
cord-285778-80baxwgc	283	11	and	and	CC
cord-285778-80baxwgc	283	12	eliminate	eliminate	VB
cord-285778-80baxwgc	283	13	it	-PRON-	PRP
cord-285778-80baxwgc	283	14	.	.	.
cord-285778-80baxwgc	284	1	In	in	IN
cord-285778-80baxwgc	284	2	contrast	contrast	NN
cord-285778-80baxwgc	284	3	,	,	,
cord-285778-80baxwgc	284	4	a	a	DT
cord-285778-80baxwgc	284	5	slow	slow	RB
cord-285778-80baxwgc	284	6	-	-	HYPH
cord-285778-80baxwgc	284	7	replicating	replicate	VBG
cord-285778-80baxwgc	284	8	pathogen	pathogen	NN
cord-285778-80baxwgc	284	9	may	may	MD
cord-285778-80baxwgc	284	10	generate	generate	VB
cord-285778-80baxwgc	284	11	only	only	RB
cord-285778-80baxwgc	284	12	low	low	JJ
cord-285778-80baxwgc	284	13	levels	level	NNS
cord-285778-80baxwgc	284	14	of	of	IN
cord-285778-80baxwgc	284	15	DAMPs	damp	NNS
cord-285778-80baxwgc	284	16	and	and	CC
cord-285778-80baxwgc	284	17	PAMPs	pamp	NNS
cord-285778-80baxwgc	284	18	that	that	WDT
cord-285778-80baxwgc	284	19	do	do	VBP
cord-285778-80baxwgc	284	20	not	not	RB
cord-285778-80baxwgc	284	21	activate	activate	VB
cord-285778-80baxwgc	284	22	large	large	JJ
cord-285778-80baxwgc	284	23	numbers	number	NNS
cord-285778-80baxwgc	284	24	of	of	IN
cord-285778-80baxwgc	284	25	APCs	apc	NNS
cord-285778-80baxwgc	284	26	,	,	,
cord-285778-80baxwgc	284	27	delaying	delay	VBG
cord-285778-80baxwgc	284	28	the	the	DT
cord-285778-80baxwgc	284	29	T	T	NNP
cord-285778-80baxwgc	284	30	cell	cell	NN
cord-285778-80baxwgc	284	31	response	response	NN
cord-285778-80baxwgc	284	32	.	.	.
cord-285778-80baxwgc	285	1	Even	even	RB
cord-285778-80baxwgc	285	2	once	once	IN
cord-285778-80baxwgc	285	3	the	the	DT
cord-285778-80baxwgc	285	4	T	T	NNP
cord-285778-80baxwgc	285	5	cell	cell	NN
cord-285778-80baxwgc	285	6	response	response	NN
cord-285778-80baxwgc	285	7	is	be	VBZ
cord-285778-80baxwgc	285	8	initiated	initiate	VBN
cord-285778-80baxwgc	285	9	,	,	,
cord-285778-80baxwgc	285	10	without	without	IN
cord-285778-80baxwgc	285	11	sufficient	sufficient	JJ
cord-285778-80baxwgc	285	12	cytokines	cytokine	NNS
cord-285778-80baxwgc	285	13	produced	produce	VBN
cord-285778-80baxwgc	285	14	by	by	IN
cord-285778-80baxwgc	285	15	activated	activate	VBN
cord-285778-80baxwgc	285	16	APCs	apc	NNS
cord-285778-80baxwgc	285	17	,	,	,
cord-285778-80baxwgc	285	18	T	t	NN
cord-285778-80baxwgc	285	19	cell	cell	NN
cord-285778-80baxwgc	285	20	proliferation	proliferation	NN
cord-285778-80baxwgc	285	21	may	may	MD
cord-285778-80baxwgc	285	22	be	be	VB
cord-285778-80baxwgc	285	23	slow	slow	JJ
cord-285778-80baxwgc	285	24	and	and	CC
cord-285778-80baxwgc	285	25	insufficient	insufficient	JJ
cord-285778-80baxwgc	285	26	to	to	TO
cord-285778-80baxwgc	285	27	completely	completely	RB
cord-285778-80baxwgc	285	28	eliminate	eliminate	VB
cord-285778-80baxwgc	285	29	the	the	DT
cord-285778-80baxwgc	285	30	pathogen	pathogen	NN
cord-285778-80baxwgc	285	31	.	.	.
cord-285778-80baxwgc	286	1	The	the	DT
cord-285778-80baxwgc	286	2	pathogen	pathogen	NN
cord-285778-80baxwgc	286	3	then	then	RB
cord-285778-80baxwgc	286	4	survives	survive	VBZ
cord-285778-80baxwgc	286	5	to	to	TO
cord-285778-80baxwgc	286	6	establish	establish	VB
cord-285778-80baxwgc	286	7	a	a	DT
cord-285778-80baxwgc	286	8	low	low	JJ
cord-285778-80baxwgc	286	9	level	level	NN
cord-285778-80baxwgc	286	10	of	of	IN
cord-285778-80baxwgc	286	11	infection	infection	NN
cord-285778-80baxwgc	286	12	that	that	WDT
cord-285778-80baxwgc	286	13	does	do	VBZ
cord-285778-80baxwgc	286	14	n't	not	RB
cord-285778-80baxwgc	286	15	kill	kill	VB
cord-285778-80baxwgc	286	16	the	the	DT
cord-285778-80baxwgc	286	17	host	host	NN
cord-285778-80baxwgc	286	18	but	but	CC
cord-285778-80baxwgc	286	19	makes	make	VBZ
cord-285778-80baxwgc	286	20	him	-PRON-	PRP
cord-285778-80baxwgc	286	21	/	/	SYM
cord-285778-80baxwgc	286	22	her	-PRON-	PRP$
cord-285778-80baxwgc	286	23	miserable	miserable	JJ
cord-285778-80baxwgc	286	24	.	.	.
cord-285778-80baxwgc	287	1	The	the	DT
cord-285778-80baxwgc	287	2	memory	memory	NN
cord-285778-80baxwgc	287	3	T	T	NNP
cord-285778-80baxwgc	287	4	cell	cell	NN
cord-285778-80baxwgc	287	5	response	response	NN
cord-285778-80baxwgc	287	6	is	be	VBZ
cord-285778-80baxwgc	287	7	of	of	IN
cord-285778-80baxwgc	287	8	little	little	JJ
cord-285778-80baxwgc	287	9	help	help	NN
cord-285778-80baxwgc	287	10	,	,	,
cord-285778-80baxwgc	287	11	as	as	IN
cord-285778-80baxwgc	287	12	it	-PRON-	PRP
cord-285778-80baxwgc	287	13	only	only	RB
cord-285778-80baxwgc	287	14	controls	control	VBZ
cord-285778-80baxwgc	287	15	rather	rather	RB
cord-285778-80baxwgc	287	16	than	than	IN
cord-285778-80baxwgc	287	17	eliminates	eliminate	VBZ
cord-285778-80baxwgc	287	18	the	the	DT
cord-285778-80baxwgc	287	19	slow	slow	RB
cord-285778-80baxwgc	287	20	-	-	HYPH
cord-285778-80baxwgc	287	21	replicating	replicate	VBG
cord-285778-80baxwgc	287	22	pathogen	pathogen	NN
cord-285778-80baxwgc	287	23	.	.	.
cord-285778-80baxwgc	288	1	An	an	DT
cord-285778-80baxwgc	288	2	uneasy	uneasy	JJ
cord-285778-80baxwgc	288	3	balance	balance	NN
cord-285778-80baxwgc	288	4	is	be	VBZ
cord-285778-80baxwgc	288	5	set	set	VBN
cord-285778-80baxwgc	288	6	up	up	RP
cord-285778-80baxwgc	288	7	between	between	IN
cord-285778-80baxwgc	288	8	the	the	DT
cord-285778-80baxwgc	288	9	pathogen	pathogen	NN
cord-285778-80baxwgc	288	10	and	and	CC
cord-285778-80baxwgc	288	11	the	the	DT
cord-285778-80baxwgc	288	12	host	host	NN
cord-285778-80baxwgc	288	13	immune	immune	JJ
cord-285778-80baxwgc	288	14	system	system	NN
cord-285778-80baxwgc	288	15	that	that	WDT
cord-285778-80baxwgc	288	16	results	result	VBZ
cord-285778-80baxwgc	288	17	in	in	IN
cord-285778-80baxwgc	288	18	chronic	chronic	JJ
cord-285778-80baxwgc	288	19	infection	infection	NN
cord-285778-80baxwgc	288	20	.	.	.
cord-285778-80baxwgc	289	1	The	the	DT
cord-285778-80baxwgc	289	2	contrast	contrast	NN
cord-285778-80baxwgc	289	3	in	in	IN
cord-285778-80baxwgc	289	4	immune	immune	JJ
cord-285778-80baxwgc	289	5	response	response	NN
cord-285778-80baxwgc	289	6	kinetics	kinetic	NNS
cord-285778-80baxwgc	289	7	between	between	IN
cord-285778-80baxwgc	289	8	what	what	WP
cord-285778-80baxwgc	289	9	the	the	DT
cord-285778-80baxwgc	289	10	authors	author	NNS
cord-285778-80baxwgc	289	11	call	call	VBP
cord-285778-80baxwgc	289	12	"	"	``
cord-285778-80baxwgc	289	13	fast	fast	JJ
cord-285778-80baxwgc	289	14	"	"	''
cord-285778-80baxwgc	289	15	and	and	CC
cord-285778-80baxwgc	289	16	"	"	``
cord-285778-80baxwgc	289	17	slow	slow	JJ
cord-285778-80baxwgc	289	18	"	"	''
cord-285778-80baxwgc	289	19	pathogens	pathogen	NNS
cord-285778-80baxwgc	289	20	is	be	VBZ
cord-285778-80baxwgc	289	21	illustrated	illustrate	VBN
cord-285778-80baxwgc	289	22	in	in	IN
cord-285778-80baxwgc	289	23	Figure	figure	NN
cord-285778-80baxwgc	289	24	1	1	CD
cord-285778-80baxwgc	289	25	from	from	IN
cord-285778-80baxwgc	289	26	their	-PRON-	PRP$
cord-285778-80baxwgc	289	27	article	article	NN
cord-285778-80baxwgc	289	28	.	.	.
cord-285778-80baxwgc	290	1	"	"	``
cord-285778-80baxwgc	290	2	The	the	DT
cord-285778-80baxwgc	290	3	Race	race	NN
cord-285778-80baxwgc	290	4	between	between	IN
cord-285778-80baxwgc	290	5	Infection	infection	NN
cord-285778-80baxwgc	290	6	and	and	CC
cord-285778-80baxwgc	290	7	Immunity	immunity	NN
cord-285778-80baxwgc	290	8	:	:	:
cord-285778-80baxwgc	290	9	How	how	WRB
cord-285778-80baxwgc	290	10	do	do	VBP
cord-285778-80baxwgc	290	11	Pathogens	Pathogens	NNPS
cord-285778-80baxwgc	290	12	Set	set	VB
cord-285778-80baxwgc	290	13	the	the	DT
cord-285778-80baxwgc	290	14	Pace	pace	NN
cord-285778-80baxwgc	290	15	?	?	.
cord-285778-80baxwgc	290	16	"	"	''
cord-285778-80baxwgc	290	17	by	by	IN
cord-285778-80baxwgc	290	18	Davenport	Davenport	NNP
cord-285778-80baxwgc	290	19	,	,	,
cord-285778-80baxwgc	290	20	M.P.	M.P.	NNP
cord-285778-80baxwgc	290	21	,	,	,
cord-285778-80baxwgc	290	22	Belz	Belz	NNP
cord-285778-80baxwgc	290	23	,	,	,
cord-285778-80baxwgc	290	24	G.	G.	NNP
cord-285778-80baxwgc	290	25	T.	T.	NNP
cord-285778-80baxwgc	290	26	and	and	CC
cord-285778-80baxwgc	290	27	Ribeiro	Ribeiro	NNP
cord-285778-80baxwgc	290	28	,	,	,
cord-285778-80baxwgc	290	29	R.M.	R.M.	NNP
cord-285778-80baxwgc	290	30	,	,	,
cord-285778-80baxwgc	290	31	(	(	-LRB-
cord-285778-80baxwgc	290	32	2009	2009	CD
cord-285778-80baxwgc	290	33	)	)	-RRB-
cord-285778-80baxwgc	290	34	 	 	_SP
cord-285778-80baxwgc	291	1	When	when	WRB
cord-285778-80baxwgc	291	2	the	the	DT
cord-285778-80baxwgc	291	3	immune	immune	JJ
cord-285778-80baxwgc	291	4	system	system	NN
cord-285778-80baxwgc	291	5	is	be	VBZ
cord-285778-80baxwgc	291	6	functioning	function	VBG
cord-285778-80baxwgc	291	7	normally	normally	RB
cord-285778-80baxwgc	291	8	,	,	,
cord-285778-80baxwgc	291	9	harmful	harmful	JJ
cord-285778-80baxwgc	291	10	entities	entity	NNS
cord-285778-80baxwgc	291	11	are	be	VBP
cord-285778-80baxwgc	291	12	recognized	recognize	VBN
cord-285778-80baxwgc	291	13	,	,	,
cord-285778-80baxwgc	291	14	and	and	CC
cord-285778-80baxwgc	291	15	the	the	DT
cord-285778-80baxwgc	291	16	host	host	NN
cord-285778-80baxwgc	291	17	is	be	VBZ
cord-285778-80baxwgc	291	18	protected	protect	VBN
cord-285778-80baxwgc	291	19	from	from	IN
cord-285778-80baxwgc	291	20	external	external	JJ
cord-285778-80baxwgc	291	21	attack	attack	NN
cord-285778-80baxwgc	291	22	by	by	IN
cord-285778-80baxwgc	291	23	pathogens	pathogen	NNS
cord-285778-80baxwgc	291	24	and	and	CC
cord-285778-80baxwgc	291	25	internal	internal	JJ
cord-285778-80baxwgc	291	26	attack	attack	NN
cord-285778-80baxwgc	291	27	by	by	IN
cord-285778-80baxwgc	291	28	cancers	cancer	NNS
cord-285778-80baxwgc	291	29	.	.	.
cord-285778-80baxwgc	292	1	Some	some	DT
cord-285778-80baxwgc	292	2	localized	localize	VBN
cord-285778-80baxwgc	292	3	tissue	tissue	NN
cord-285778-80baxwgc	292	4	damage	damage	NN
cord-285778-80baxwgc	292	5	may	may	MD
cord-285778-80baxwgc	292	6	result	result	VB
cord-285778-80baxwgc	292	7	from	from	IN
cord-285778-80baxwgc	292	8	the	the	DT
cord-285778-80baxwgc	292	9	normal	normal	JJ
cord-285778-80baxwgc	292	10	inflammatory	inflammatory	JJ
cord-285778-80baxwgc	292	11	response	response	NN
cord-285778-80baxwgc	292	12	that	that	WDT
cord-285778-80baxwgc	292	13	develops	develop	VBZ
cord-285778-80baxwgc	292	14	as	as	IN
cord-285778-80baxwgc	292	15	innate	innate	JJ
cord-285778-80baxwgc	292	16	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	292	17	work	work	VBP
cord-285778-80baxwgc	292	18	to	to	TO
cord-285778-80baxwgc	292	19	eliminate	eliminate	VB
cord-285778-80baxwgc	292	20	the	the	DT
cord-285778-80baxwgc	292	21	threat	threat	NN
cord-285778-80baxwgc	292	22	,	,	,
cord-285778-80baxwgc	292	23	but	but	CC
cord-285778-80baxwgc	292	24	these	these	DT
cord-285778-80baxwgc	292	25	immunopathic	immunopathic	JJ
cord-285778-80baxwgc	292	26	effects	effect	NNS
cord-285778-80baxwgc	292	27	are	be	VBP
cord-285778-80baxwgc	292	28	limited	limit	VBN
cord-285778-80baxwgc	292	29	and	and	CC
cord-285778-80baxwgc	292	30	controlled	control	VBN
cord-285778-80baxwgc	292	31	.	.	.
cord-285778-80baxwgc	293	1	As	as	RB
cord-285778-80baxwgc	293	2	well	well	RB
cord-285778-80baxwgc	293	3	,	,	,
cord-285778-80baxwgc	293	4	the	the	DT
cord-285778-80baxwgc	293	5	tolerance	tolerance	NN
cord-285778-80baxwgc	293	6	of	of	IN
cord-285778-80baxwgc	293	7	the	the	DT
cord-285778-80baxwgc	293	8	healthy	healthy	JJ
cord-285778-80baxwgc	293	9	immune	immune	JJ
cord-285778-80baxwgc	293	10	system	system	NN
cord-285778-80baxwgc	293	11	prevents	prevent	VBZ
cord-285778-80baxwgc	293	12	cells	cell	NNS
cord-285778-80baxwgc	293	13	of	of	IN
cord-285778-80baxwgc	293	14	the	the	DT
cord-285778-80baxwgc	293	15	adaptive	adaptive	JJ
cord-285778-80baxwgc	293	16	response	response	NN
cord-285778-80baxwgc	293	17	from	from	IN
cord-285778-80baxwgc	293	18	attacking	attack	VBG
cord-285778-80baxwgc	293	19	normal	normal	JJ
cord-285778-80baxwgc	293	20	self	self	NN
cord-285778-80baxwgc	293	21	tissues	tissue	NNS
cord-285778-80baxwgc	293	22	.	.	.
cord-285778-80baxwgc	294	1	Sometimes	sometimes	RB
cord-285778-80baxwgc	294	2	a	a	DT
cord-285778-80baxwgc	294	3	person	person	NN
cord-285778-80baxwgc	294	4	's	's	POS
cord-285778-80baxwgc	294	5	immune	immune	JJ
cord-285778-80baxwgc	294	6	system	system	NN
cord-285778-80baxwgc	294	7	is	be	VBZ
cord-285778-80baxwgc	294	8	incomplete	incomplete	JJ
cord-285778-80baxwgc	294	9	,	,	,
cord-285778-80baxwgc	294	10	either	either	CC
cord-285778-80baxwgc	294	11	because	because	IN
cord-285778-80baxwgc	294	12	of	of	IN
cord-285778-80baxwgc	294	13	primary	primary	JJ
cord-285778-80baxwgc	294	14	immunodeficiency	immunodeficiency	NN
cord-285778-80baxwgc	294	15	or	or	CC
cord-285778-80baxwgc	294	16	acquired	acquire	VBN
cord-285778-80baxwgc	294	17	immunodeficiency	immunodeficiency	NN
cord-285778-80baxwgc	294	18	.	.	.
cord-285778-80baxwgc	295	1	In	in	IN
cord-285778-80baxwgc	295	2	primary	primary	JJ
cord-285778-80baxwgc	295	3	immunodeficiencies	immunodeficiency	NNS
cord-285778-80baxwgc	295	4	,	,	,
cord-285778-80baxwgc	295	5	the	the	DT
cord-285778-80baxwgc	295	6	failure	failure	NN
cord-285778-80baxwgc	295	7	of	of	IN
cord-285778-80baxwgc	295	8	the	the	DT
cord-285778-80baxwgc	295	9	immune	immune	JJ
cord-285778-80baxwgc	295	10	system	system	NN
cord-285778-80baxwgc	295	11	is	be	VBZ
cord-285778-80baxwgc	295	12	congenital	congenital	JJ
cord-285778-80baxwgc	295	13	;	;	:
cord-285778-80baxwgc	295	14	that	that	RB
cord-285778-80baxwgc	295	15	is	is	RB
cord-285778-80baxwgc	295	16	,	,	,
cord-285778-80baxwgc	295	17	an	an	DT
cord-285778-80baxwgc	295	18	affected	affected	JJ
cord-285778-80baxwgc	295	19	individual	individual	NN
cord-285778-80baxwgc	295	20	is	be	VBZ
cord-285778-80baxwgc	295	21	born	bear	VBN
cord-285778-80baxwgc	295	22	with	with	IN
cord-285778-80baxwgc	295	23	a	a	DT
cord-285778-80baxwgc	295	24	genetic	genetic	JJ
cord-285778-80baxwgc	295	25	defect	defect	NN
cord-285778-80baxwgc	295	26	that	that	WDT
cord-285778-80baxwgc	295	27	impairs	impair	VBZ
cord-285778-80baxwgc	295	28	his	-PRON-	PRP$
cord-285778-80baxwgc	295	29	/	/	SYM
cord-285778-80baxwgc	295	30	her	-PRON-	PRP$
cord-285778-80baxwgc	295	31	ability	ability	NN
cord-285778-80baxwgc	295	32	to	to	TO
cord-285778-80baxwgc	295	33	mount	mount	VB
cord-285778-80baxwgc	295	34	innate	innate	JJ
cord-285778-80baxwgc	295	35	and/or	and/or	CC
cord-285778-80baxwgc	295	36	adaptive	adaptive	JJ
cord-285778-80baxwgc	295	37	immune	immune	JJ
cord-285778-80baxwgc	295	38	responses	response	NNS
cord-285778-80baxwgc	295	39	.	.	.
cord-285778-80baxwgc	296	1	In	in	IN
cord-285778-80baxwgc	296	2	an	an	DT
cord-285778-80baxwgc	296	3	acquired	acquire	VBN
cord-285778-80baxwgc	296	4	immunodeficiency	immunodeficiency	NN
cord-285778-80baxwgc	296	5	,	,	,
cord-285778-80baxwgc	296	6	an	an	DT
cord-285778-80baxwgc	296	7	external	external	JJ
cord-285778-80baxwgc	296	8	factor	factor	NN
cord-285778-80baxwgc	296	9	such	such	JJ
cord-285778-80baxwgc	296	10	as	as	IN
cord-285778-80baxwgc	296	11	a	a	DT
cord-285778-80baxwgc	296	12	nutritional	nutritional	JJ
cord-285778-80baxwgc	296	13	A	a	DT
cord-285778-80baxwgc	296	14	healthy	healthy	JJ
cord-285778-80baxwgc	296	15	immune	immune	JJ
cord-285778-80baxwgc	296	16	response	response	NN
cord-285778-80baxwgc	296	17	is	be	VBZ
cord-285778-80baxwgc	296	18	crucial	crucial	JJ
cord-285778-80baxwgc	296	19	for	for	IN
cord-285778-80baxwgc	296	20	providing	provide	VBG
cord-285778-80baxwgc	296	21	an	an	DT
cord-285778-80baxwgc	296	22	individual	individual	NN
cord-285778-80baxwgc	296	23	with	with	IN
cord-285778-80baxwgc	296	24	immunity	immunity	NN
cord-285778-80baxwgc	296	25	to	to	IN
cord-285778-80baxwgc	296	26	infectious	infectious	JJ
cord-285778-80baxwgc	296	27	diseases	disease	NNS
cord-285778-80baxwgc	296	28	(	(	-LRB-
cord-285778-80baxwgc	296	29	Ch	Ch	NNP
cord-285778-80baxwgc	296	30	.	.	NNP
cord-285778-80baxwgc	296	31	13	13	CD
cord-285778-80baxwgc	296	32	)	)	-RRB-
cord-285778-80baxwgc	296	33	and	and	CC
cord-285778-80baxwgc	296	34	may	may	MD
cord-285778-80baxwgc	296	35	be	be	VB
cord-285778-80baxwgc	296	36	made	make	VBN
cord-285778-80baxwgc	296	37	more	more	RBR
cord-285778-80baxwgc	296	38	robust	robust	JJ
cord-285778-80baxwgc	296	39	through	through	IN
cord-285778-80baxwgc	296	40	vaccination	vaccination	NN
cord-285778-80baxwgc	296	41	(	(	-LRB-
cord-285778-80baxwgc	296	42	Ch	Ch	NNP
cord-285778-80baxwgc	296	43	.	.	NNP
cord-285778-80baxwgc	296	44	14	14	CD
cord-285778-80baxwgc	296	45	)	)	-RRB-
cord-285778-80baxwgc	296	46	.	.	.
cord-285778-80baxwgc	297	1	Innate	innate	JJ
cord-285778-80baxwgc	297	2	and	and	CC
cord-285778-80baxwgc	297	3	adaptive	adaptive	JJ
cord-285778-80baxwgc	297	4	immune	immune	JJ
cord-285778-80baxwgc	297	5	mechanisms	mechanism	NNS
cord-285778-80baxwgc	297	6	work	work	VBP
cord-285778-80baxwgc	297	7	together	together	RB
cord-285778-80baxwgc	297	8	to	to	TO
cord-285778-80baxwgc	297	9	allow	allow	VB
cord-285778-80baxwgc	297	10	a	a	DT
cord-285778-80baxwgc	297	11	full	full	JJ
cord-285778-80baxwgc	297	12	range	range	NN
cord-285778-80baxwgc	297	13	of	of	IN
cord-285778-80baxwgc	297	14	responses	response	NNS
cord-285778-80baxwgc	297	15	of	of	IN
cord-285778-80baxwgc	297	16	appropriate	appropriate	JJ
cord-285778-80baxwgc	297	17	strength	strength	NN
cord-285778-80baxwgc	297	18	and	and	CC
cord-285778-80baxwgc	297	19	specificity	specificity	NN
cord-285778-80baxwgc	297	20	.	.	.
cord-285778-80baxwgc	298	1	In	in	IN
cord-285778-80baxwgc	298	2	addition	addition	NN
cord-285778-80baxwgc	298	3	to	to	IN
cord-285778-80baxwgc	298	4	their	-PRON-	PRP$
cord-285778-80baxwgc	298	5	direct	direct	JJ
cord-285778-80baxwgc	298	6	and	and	CC
cord-285778-80baxwgc	298	7	broadly	broadly	RB
cord-285778-80baxwgc	298	8	protective	protective	JJ
cord-285778-80baxwgc	298	9	role	role	NN
cord-285778-80baxwgc	298	10	,	,	,
cord-285778-80baxwgc	298	11	innate	innate	JJ
cord-285778-80baxwgc	298	12	immune	immune	JJ
cord-285778-80baxwgc	298	13	responses	response	NNS
cord-285778-80baxwgc	298	14	recruit	recruit	VBP
cord-285778-80baxwgc	298	15	adaptive	adaptive	JJ
cord-285778-80baxwgc	298	16	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	298	17	and	and	CC
cord-285778-80baxwgc	298	18	contribute	contribute	VB
cord-285778-80baxwgc	298	19	to	to	IN
cord-285778-80baxwgc	298	20	their	-PRON-	PRP$
cord-285778-80baxwgc	298	21	activation	activation	NN
cord-285778-80baxwgc	298	22	.	.	.
cord-285778-80baxwgc	299	1	Once	once	RB
cord-285778-80baxwgc	299	2	activated	activate	VBN
cord-285778-80baxwgc	299	3	,	,	,
cord-285778-80baxwgc	299	4	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	299	5	mount	mount	VBP
cord-285778-80baxwgc	299	6	humoral	humoral	JJ
cord-285778-80baxwgc	299	7	and	and	CC
cord-285778-80baxwgc	299	8	cell	cell	NN
cord-285778-80baxwgc	299	9	-	-	HYPH
cord-285778-80baxwgc	299	10	mediated	mediate	VBN
cord-285778-80baxwgc	299	11	antipathogen	antipathogen	NNP
cord-285778-80baxwgc	299	12	responses	response	NNS
cord-285778-80baxwgc	299	13	that	that	WDT
cord-285778-80baxwgc	299	14	are	be	VBP
cord-285778-80baxwgc	299	15	highly	highly	RB
cord-285778-80baxwgc	299	16	specific	specific	JJ
cord-285778-80baxwgc	299	17	.	.	.
cord-285778-80baxwgc	300	1	Cytokines	cytokine	NNS
cord-285778-80baxwgc	300	2	are	be	VBP
cord-285778-80baxwgc	300	3	produced	produce	VBN
cord-285778-80baxwgc	300	4	that	that	IN
cord-285778-80baxwgc	300	5	further	further	RB
cord-285778-80baxwgc	300	6	stimulate	stimulate	VBP
cord-285778-80baxwgc	300	7	both	both	CC
cord-285778-80baxwgc	300	8	the	the	DT
cord-285778-80baxwgc	300	9	innate	innate	JJ
cord-285778-80baxwgc	300	10	and	and	CC
cord-285778-80baxwgc	300	11	adaptive	adaptive	JJ
cord-285778-80baxwgc	300	12	responses	response	NNS
cord-285778-80baxwgc	300	13	.	.	.
cord-285778-80baxwgc	301	1	Innate	innate	JJ
cord-285778-80baxwgc	301	2	and	and	CC
cord-285778-80baxwgc	301	3	adaptive	adaptive	JJ
cord-285778-80baxwgc	301	4	immunity	immunity	NN
cord-285778-80baxwgc	301	5	thus	thus	RB
cord-285778-80baxwgc	301	6	work	work	NN
cord-285778-80baxwgc	301	7	synergistically	synergistically	RB
cord-285778-80baxwgc	301	8	to	to	TO
cord-285778-80baxwgc	301	9	protect	protect	VB
cord-285778-80baxwgc	301	10	the	the	DT
cord-285778-80baxwgc	301	11	host	host	NN
cord-285778-80baxwgc	301	12	from	from	IN
cord-285778-80baxwgc	301	13	all	all	DT
cord-285778-80baxwgc	301	14	threats	threat	NNS
cord-285778-80baxwgc	301	15	.	.	.
cord-285778-80baxwgc	302	1	Cell	cell	NN
cord-285778-80baxwgc	302	2	-	-	HYPH
cord-285778-80baxwgc	302	3	mediated	mediate	VBN
cord-285778-80baxwgc	302	4	The	the	DT
cord-285778-80baxwgc	302	5	pace	pace	NN
cord-285778-80baxwgc	302	6	of	of	IN
cord-285778-80baxwgc	302	7	pathogen	pathogen	NN
cord-285778-80baxwgc	302	8	replication	replication	NN
cord-285778-80baxwgc	302	9	may	may	MD
cord-285778-80baxwgc	302	10	have	have	VB
cord-285778-80baxwgc	302	11	implications	implication	NNS
cord-285778-80baxwgc	302	12	for	for	IN
cord-285778-80baxwgc	302	13	vaccination	vaccination	NN
cord-285778-80baxwgc	302	14	strategies	strategy	NNS
cord-285778-80baxwgc	302	15	.	.	.
cord-285778-80baxwgc	303	1	Currently	currently	RB
cord-285778-80baxwgc	303	2	,	,	,
cord-285778-80baxwgc	303	3	vaccination	vaccination	NN
cord-285778-80baxwgc	303	4	often	often	RB
cord-285778-80baxwgc	303	5	uses	use	VBZ
cord-285778-80baxwgc	303	6	a	a	DT
cord-285778-80baxwgc	303	7	harmless	harmless	JJ
cord-285778-80baxwgc	303	8	pathogen	pathogen	NN
cord-285778-80baxwgc	303	9	antigen	antigen	NN
cord-285778-80baxwgc	303	10	to	to	TO
cord-285778-80baxwgc	303	11	induce	induce	VB
cord-285778-80baxwgc	303	12	the	the	DT
cord-285778-80baxwgc	303	13	host	host	NN
cord-285778-80baxwgc	303	14	to	to	TO
cord-285778-80baxwgc	303	15	respond	respond	VB
cord-285778-80baxwgc	303	16	and	and	CC
cord-285778-80baxwgc	303	17	generate	generate	VB
cord-285778-80baxwgc	303	18	large	large	JJ
cord-285778-80baxwgc	303	19	populations	population	NNS
cord-285778-80baxwgc	303	20	of	of	IN
cord-285778-80baxwgc	303	21	memory	memory	NN
cord-285778-80baxwgc	303	22	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	303	23	,	,	,
cord-285778-80baxwgc	303	24	which	which	WDT
cord-285778-80baxwgc	303	25	stand	stand	VBP
cord-285778-80baxwgc	303	26	guard	guard	NN
cord-285778-80baxwgc	303	27	ready	ready	JJ
cord-285778-80baxwgc	303	28	to	to	TO
cord-285778-80baxwgc	303	29	mount	mount	VB
cord-285778-80baxwgc	303	30	a	a	DT
cord-285778-80baxwgc	303	31	faster	fast	JJR
cord-285778-80baxwgc	303	32	and	and	CC
cord-285778-80baxwgc	303	33	stronger	strong	JJR
cord-285778-80baxwgc	303	34	response	response	NN
cord-285778-80baxwgc	303	35	should	should	MD
cord-285778-80baxwgc	303	36	the	the	DT
cord-285778-80baxwgc	303	37	real	real	JJ
cord-285778-80baxwgc	303	38	pathogen	pathogen	NN
cord-285778-80baxwgc	303	39	attack	attack	NN
cord-285778-80baxwgc	303	40	.	.	.
cord-285778-80baxwgc	304	1	For	for	IN
cord-285778-80baxwgc	304	2	a	a	DT
cord-285778-80baxwgc	304	3	fast	fast	RB
cord-285778-80baxwgc	304	4	-	-	HYPH
cord-285778-80baxwgc	304	5	replicating	replicate	VBG
cord-285778-80baxwgc	304	6	pathogen	pathogen	NN
cord-285778-80baxwgc	304	7	,	,	,
cord-285778-80baxwgc	304	8	this	this	DT
cord-285778-80baxwgc	304	9	tactic	tactic	NN
cord-285778-80baxwgc	304	10	is	be	VBZ
cord-285778-80baxwgc	304	11	successful	successful	JJ
cord-285778-80baxwgc	304	12	because	because	IN
cord-285778-80baxwgc	304	13	these	these	DT
cord-285778-80baxwgc	304	14	types	type	NNS
cord-285778-80baxwgc	304	15	of	of	IN
cord-285778-80baxwgc	304	16	pathogens	pathogen	NNS
cord-285778-80baxwgc	304	17	readily	readily	RB
cord-285778-80baxwgc	304	18	generate	generate	VBP
cord-285778-80baxwgc	304	19	enough	enough	JJ
cord-285778-80baxwgc	304	20	PAMPs	pamp	NNS
cord-285778-80baxwgc	304	21	,	,	,
cord-285778-80baxwgc	304	22	DAMPs	damp	NNS
cord-285778-80baxwgc	304	23	and	and	CC
cord-285778-80baxwgc	304	24	antigen	antigen	NN
cord-285778-80baxwgc	304	25	to	to	TO
cord-285778-80baxwgc	304	26	surpass	surpass	VB
cord-285778-80baxwgc	304	27	the	the	DT
cord-285778-80baxwgc	304	28	thresholds	threshold	NNS
cord-285778-80baxwgc	304	29	of	of	IN
cord-285778-80baxwgc	304	30	APC	APC	NNP
cord-285778-80baxwgc	304	31	and	and	CC
cord-285778-80baxwgc	304	32	T	T	NNP
cord-285778-80baxwgc	304	33	cell	cell	NN
cord-285778-80baxwgc	304	34	activation	activation	NN
cord-285778-80baxwgc	304	35	.	.	.
cord-285778-80baxwgc	305	1	With	with	IN
cord-285778-80baxwgc	305	2	the	the	DT
cord-285778-80baxwgc	305	3	"	"	``
cord-285778-80baxwgc	305	4	head	head	NN
cord-285778-80baxwgc	305	5	start	start	NN
cord-285778-80baxwgc	305	6	"	"	''
cord-285778-80baxwgc	305	7	provided	provide	VBN
cord-285778-80baxwgc	305	8	by	by	IN
cord-285778-80baxwgc	305	9	memory	memory	NN
cord-285778-80baxwgc	305	10	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	305	11	,	,	,
cord-285778-80baxwgc	305	12	the	the	DT
cord-285778-80baxwgc	305	13	pathogen	pathogen	NN
cord-285778-80baxwgc	305	14	may	may	MD
cord-285778-80baxwgc	305	15	not	not	RB
cord-285778-80baxwgc	305	16	get	get	VB
cord-285778-80baxwgc	305	17	to	to	TO
cord-285778-80baxwgc	305	18	replicate	replicate	VB
cord-285778-80baxwgc	305	19	at	at	RB
cord-285778-80baxwgc	305	20	all	all	RB
cord-285778-80baxwgc	305	21	.	.	.
cord-285778-80baxwgc	306	1	However	however	RB
cord-285778-80baxwgc	306	2	,	,	,
cord-285778-80baxwgc	306	3	a	a	DT
cord-285778-80baxwgc	306	4	slow	slow	RB
cord-285778-80baxwgc	306	5	-	-	HYPH
cord-285778-80baxwgc	306	6	replicating	replicate	VBG
cord-285778-80baxwgc	306	7	pathogen	pathogen	NN
cord-285778-80baxwgc	306	8	may	may	MD
cord-285778-80baxwgc	306	9	not	not	RB
cord-285778-80baxwgc	306	10	provide	provide	VB
cord-285778-80baxwgc	306	11	sufficient	sufficient	JJ
cord-285778-80baxwgc	306	12	antigen	antigen	NN
cord-285778-80baxwgc	306	13	to	to	TO
cord-285778-80baxwgc	306	14	reach	reach	VB
cord-285778-80baxwgc	306	15	even	even	RB
cord-285778-80baxwgc	306	16	the	the	DT
cord-285778-80baxwgc	306	17	lower	low	JJR
cord-285778-80baxwgc	306	18	threshold	threshold	NN
cord-285778-80baxwgc	306	19	required	require	VBN
cord-285778-80baxwgc	306	20	by	by	IN
cord-285778-80baxwgc	306	21	memory	memory	NN
cord-285778-80baxwgc	306	22	T	T	NNP
cord-285778-80baxwgc	306	23	cells	cell	NNS
cord-285778-80baxwgc	306	24	,	,	,
cord-285778-80baxwgc	306	25	meaning	mean	VBG
cord-285778-80baxwgc	306	26	that	that	IN
cord-285778-80baxwgc	306	27	the	the	DT
cord-285778-80baxwgc	306	28	vaccine	vaccine	NN
cord-285778-80baxwgc	306	29	will	will	MD
cord-285778-80baxwgc	306	30	not	not	RB
cord-285778-80baxwgc	306	31	have	have	VB
cord-285778-80baxwgc	306	32	offered	offer	VBN
cord-285778-80baxwgc	306	33	an	an	DT
cord-285778-80baxwgc	306	34	advantage	advantage	NN
cord-285778-80baxwgc	306	35	to	to	IN
cord-285778-80baxwgc	306	36	the	the	DT
cord-285778-80baxwgc	306	37	host	host	NN
cord-285778-80baxwgc	306	38	.	.	.
cord-285778-80baxwgc	307	1	Worse	bad	JJR
cord-285778-80baxwgc	307	2	,	,	,
cord-285778-80baxwgc	307	3	if	if	IN
cord-285778-80baxwgc	307	4	the	the	DT
cord-285778-80baxwgc	307	5	large	large	JJ
cord-285778-80baxwgc	307	6	numbers	number	NNS
cord-285778-80baxwgc	307	7	of	of	IN
cord-285778-80baxwgc	307	8	memory	memory	NN
cord-285778-80baxwgc	307	9	T	t	NN
cord-285778-80baxwgc	307	10	cells	cell	NNS
cord-285778-80baxwgc	307	11	present	present	JJ
cord-285778-80baxwgc	307	12	after	after	IN
cord-285778-80baxwgc	307	13	vaccination	vaccination	NN
cord-285778-80baxwgc	307	14	compete	compete	VBP
cord-285778-80baxwgc	307	15	for	for	IN
cord-285778-80baxwgc	307	16	the	the	DT
cord-285778-80baxwgc	307	17	miserly	miserly	JJ
cord-285778-80baxwgc	307	18	quantities	quantity	NNS
cord-285778-80baxwgc	307	19	of	of	IN
cord-285778-80baxwgc	307	20	antigen	antigen	NN
cord-285778-80baxwgc	307	21	present	present	NN
cord-285778-80baxwgc	307	22	,	,	,
cord-285778-80baxwgc	307	23	and	and	CC
cord-285778-80baxwgc	307	24	so	so	RB
cord-285778-80baxwgc	307	25	proliferate	proliferate	VB
cord-285778-80baxwgc	307	26	only	only	RB
cord-285778-80baxwgc	307	27	slowly	slowly	RB
cord-285778-80baxwgc	307	28	,	,	,
cord-285778-80baxwgc	307	29	the	the	DT
cord-285778-80baxwgc	307	30	pathogen	pathogen	NN
cord-285778-80baxwgc	307	31	may	may	MD
cord-285778-80baxwgc	307	32	in	in	IN
cord-285778-80baxwgc	307	33	fact	fact	NN
cord-285778-80baxwgc	307	34	get	get	VB
cord-285778-80baxwgc	307	35	a	a	DT
cord-285778-80baxwgc	307	36	better	well	JJR
cord-285778-80baxwgc	307	37	foothold	foothold	NN
cord-285778-80baxwgc	307	38	than	than	IN
cord-285778-80baxwgc	307	39	if	if	IN
cord-285778-80baxwgc	307	40	the	the	DT
cord-285778-80baxwgc	307	41	host	host	NN
cord-285778-80baxwgc	307	42	had	have	VBD
cord-285778-80baxwgc	307	43	NOT	not	RB
cord-285778-80baxwgc	307	44	been	be	VBN
cord-285778-80baxwgc	307	45	vaccinated	vaccinate	VBN
cord-285778-80baxwgc	307	46	.	.	.
cord-285778-80baxwgc	308	1	These	these	DT
cord-285778-80baxwgc	308	2	considerations	consideration	NNS
cord-285778-80baxwgc	308	3	should	should	MD
cord-285778-80baxwgc	308	4	encourage	encourage	VB
cord-285778-80baxwgc	308	5	us	-PRON-	PRP
cord-285778-80baxwgc	308	6	to	to	TO
cord-285778-80baxwgc	308	7	experimentally	experimentally	RB
cord-285778-80baxwgc	308	8	test	test	VB
cord-285778-80baxwgc	308	9	the	the	DT
cord-285778-80baxwgc	308	10	threshold	threshold	NN
cord-285778-80baxwgc	308	11	hypothesis	hypothesis	NN
cord-285778-80baxwgc	308	12	and	and	CC
cord-285778-80baxwgc	308	13	to	to	TO
cord-285778-80baxwgc	308	14	refine	refine	VB
cord-285778-80baxwgc	308	15	our	-PRON-	PRP$
cord-285778-80baxwgc	308	16	approach	approach	NN
cord-285778-80baxwgc	308	17	to	to	IN
cord-285778-80baxwgc	308	18	vaccination	vaccination	NN
cord-285778-80baxwgc	308	19	accordingly	accordingly	RB
cord-285778-80baxwgc	308	20	.	.	.
cord-285778-80baxwgc	309	1	imbalance	imbalance	NN
cord-285778-80baxwgc	309	2	or	or	CC
cord-285778-80baxwgc	309	3	a	a	DT
cord-285778-80baxwgc	309	4	pathogen	pathogen	NN
cord-285778-80baxwgc	309	5	may	may	MD
cord-285778-80baxwgc	309	6	cause	cause	VB
cord-285778-80baxwgc	309	7	the	the	DT
cord-285778-80baxwgc	309	8	loss	loss	NN
cord-285778-80baxwgc	309	9	of	of	IN
cord-285778-80baxwgc	309	10	an	an	DT
cord-285778-80baxwgc	309	11	immune	immune	JJ
cord-285778-80baxwgc	309	12	system	system	NN
cord-285778-80baxwgc	309	13	component	component	NN
cord-285778-80baxwgc	309	14	.	.	.
cord-285778-80baxwgc	310	1	For	for	IN
cord-285778-80baxwgc	310	2	example	example	NN
cord-285778-80baxwgc	310	3	,	,	,
cord-285778-80baxwgc	310	4	in	in	IN
cord-285778-80baxwgc	310	5	acquired	acquire	VBN
cord-285778-80baxwgc	310	6	immunodeficiency	immunodeficiency	NN
cord-285778-80baxwgc	310	7	syndrome	syndrome	NN
cord-285778-80baxwgc	310	8	(	(	-LRB-
cord-285778-80baxwgc	310	9	AIDS	AIDS	NNP
cord-285778-80baxwgc	310	10	)	)	-RRB-
cord-285778-80baxwgc	310	11	,	,	,
cord-285778-80baxwgc	310	12	the	the	DT
cord-285778-80baxwgc	310	13	human	human	JJ
cord-285778-80baxwgc	310	14	immunodeficiency	immunodeficiency	NN
cord-285778-80baxwgc	310	15	virus	virus	NN
cord-285778-80baxwgc	310	16	(	(	-LRB-
cord-285778-80baxwgc	310	17	HIV	HIV	NNP
cord-285778-80baxwgc	310	18	)	)	-RRB-
cord-285778-80baxwgc	310	19	destroys	destroy	VBZ
cord-285778-80baxwgc	310	20	the	the	DT
cord-285778-80baxwgc	310	21	T	t	NN
cord-285778-80baxwgc	310	22	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	310	23	needed	need	VBN
cord-285778-80baxwgc	310	24	to	to	TO
cord-285778-80baxwgc	310	25	fight	fight	VB
cord-285778-80baxwgc	310	26	infection	infection	NN
cord-285778-80baxwgc	310	27	.	.	.
cord-285778-80baxwgc	311	1	In	in	IN
cord-285778-80baxwgc	311	2	both	both	DT
cord-285778-80baxwgc	311	3	primary	primary	JJ
cord-285778-80baxwgc	311	4	and	and	CC
cord-285778-80baxwgc	311	5	acquired	acquire	VBD
cord-285778-80baxwgc	311	6	immunodeficiencies	immunodeficiency	NNS
cord-285778-80baxwgc	311	7	,	,	,
cord-285778-80baxwgc	311	8	patients	patient	NNS
cord-285778-80baxwgc	311	9	show	show	VBP
cord-285778-80baxwgc	311	10	a	a	DT
cord-285778-80baxwgc	311	11	heightened	heighten	VBN
cord-285778-80baxwgc	311	12	susceptibility	susceptibility	NN
cord-285778-80baxwgc	311	13	to	to	IN
cord-285778-80baxwgc	311	14	recurrent	recurrent	JJ
cord-285778-80baxwgc	311	15	infections	infection	NNS
cord-285778-80baxwgc	311	16	and	and	CC
cord-285778-80baxwgc	311	17	sometimes	sometimes	RB
cord-285778-80baxwgc	311	18	develop	develop	VBP
cord-285778-80baxwgc	311	19	tumors	tumor	NNS
cord-285778-80baxwgc	311	20	.	.	.
cord-285778-80baxwgc	312	1	The	the	DT
cord-285778-80baxwgc	312	2	prognosis	prognosis	NN
cord-285778-80baxwgc	312	3	for	for	IN
cord-285778-80baxwgc	312	4	most	most	JJS
cord-285778-80baxwgc	312	5	of	of	IN
cord-285778-80baxwgc	312	6	these	these	DT
cord-285778-80baxwgc	312	7	diseases	disease	NNS
cord-285778-80baxwgc	312	8	is	be	VBZ
cord-285778-80baxwgc	312	9	very	very	RB
cord-285778-80baxwgc	312	10	poor	poor	JJ
cord-285778-80baxwgc	312	11	and	and	CC
cord-285778-80baxwgc	312	12	treatment	treatment	NN
cord-285778-80baxwgc	312	13	options	option	NNS
cord-285778-80baxwgc	312	14	are	be	VBP
cord-285778-80baxwgc	312	15	limited	limited	JJ
cord-285778-80baxwgc	312	16	.	.	.
cord-285778-80baxwgc	313	1	What	what	WP
cord-285778-80baxwgc	313	2	happens	happen	VBZ
cord-285778-80baxwgc	313	3	when	when	WRB
cord-285778-80baxwgc	313	4	the	the	DT
cord-285778-80baxwgc	313	5	immune	immune	JJ
cord-285778-80baxwgc	313	6	system	system	NN
cord-285778-80baxwgc	313	7	is	be	VBZ
cord-285778-80baxwgc	313	8	complete	complete	JJ
cord-285778-80baxwgc	313	9	but	but	CC
cord-285778-80baxwgc	313	10	malfunctions	malfunction	NNS
cord-285778-80baxwgc	313	11	,	,	,
cord-285778-80baxwgc	313	12	or	or	CC
cord-285778-80baxwgc	313	13	when	when	WRB
cord-285778-80baxwgc	313	14	its	-PRON-	PRP$
cord-285778-80baxwgc	313	15	normal	normal	JJ
cord-285778-80baxwgc	313	16	functioning	functioning	NN
cord-285778-80baxwgc	313	17	has	have	VBZ
cord-285778-80baxwgc	313	18	undesirable	undesirable	JJ
cord-285778-80baxwgc	313	19	effects	effect	NNS
cord-285778-80baxwgc	313	20	?	?	.
cord-285778-80baxwgc	314	1	There	there	EX
cord-285778-80baxwgc	314	2	are	be	VBP
cord-285778-80baxwgc	314	3	several	several	JJ
cord-285778-80baxwgc	314	4	instances	instance	NNS
cord-285778-80baxwgc	314	5	in	in	IN
cord-285778-80baxwgc	314	6	which	which	WDT
cord-285778-80baxwgc	314	7	inappropriate	inappropriate	JJ
cord-285778-80baxwgc	314	8	actions	action	NNS
cord-285778-80baxwgc	314	9	of	of	IN
cord-285778-80baxwgc	314	10	the	the	DT
cord-285778-80baxwgc	314	11	immune	immune	JJ
cord-285778-80baxwgc	314	12	system	system	NN
cord-285778-80baxwgc	314	13	can	can	MD
cord-285778-80baxwgc	314	14	result	result	VB
cord-285778-80baxwgc	314	15	in	in	IN
cord-285778-80baxwgc	314	16	pathologic	pathologic	JJ
cord-285778-80baxwgc	314	17	consequences	consequence	NNS
cord-285778-80baxwgc	314	18	that	that	WDT
cord-285778-80baxwgc	314	19	tip	tip	VBP
cord-285778-80baxwgc	314	20	the	the	DT
cord-285778-80baxwgc	314	21	balance	balance	NN
cord-285778-80baxwgc	314	22	from	from	IN
cord-285778-80baxwgc	314	23	health	health	NN
cord-285778-80baxwgc	314	24	to	to	IN
cord-285778-80baxwgc	314	25	disease	disease	NN
cord-285778-80baxwgc	315	1	(	(	-LRB-
cord-285778-80baxwgc	315	2	Fig	Fig	NNP
cord-285778-80baxwgc	315	3	.	.	NNP
cord-285778-80baxwgc	315	4	1	1	CD
cord-285778-80baxwgc	315	5	-	-	SYM
cord-285778-80baxwgc	315	6	9	9	CD
cord-285778-80baxwgc	315	7	)	)	-RRB-
cord-285778-80baxwgc	315	8	.	.	.
cord-285778-80baxwgc	316	1	Firstly	firstly	RB
cord-285778-80baxwgc	316	2	,	,	,
cord-285778-80baxwgc	316	3	the	the	DT
cord-285778-80baxwgc	316	4	normal	normal	JJ
cord-285778-80baxwgc	316	5	attack	attack	NN
cord-285778-80baxwgc	316	6	of	of	IN
cord-285778-80baxwgc	316	7	a	a	DT
cord-285778-80baxwgc	316	8	healthy	healthy	JJ
cord-285778-80baxwgc	316	9	immune	immune	JJ
cord-285778-80baxwgc	316	10	system	system	NN
cord-285778-80baxwgc	316	11	on	on	IN
cord-285778-80baxwgc	316	12	a	a	DT
cord-285778-80baxwgc	316	13	foreign	foreign	JJ
cord-285778-80baxwgc	316	14	tissue	tissue	NN
cord-285778-80baxwgc	316	15	transplant	transplant	NN
cord-285778-80baxwgc	316	16	meant	mean	VBN
cord-285778-80baxwgc	316	17	to	to	TO
cord-285778-80baxwgc	316	18	preserve	preserve	VB
cord-285778-80baxwgc	316	19	life	life	NN
cord-285778-80baxwgc	316	20	results	result	NNS
cord-285778-80baxwgc	316	21	in	in	IN
cord-285778-80baxwgc	316	22	transplant	transplant	NN
cord-285778-80baxwgc	316	23	rejection	rejection	NN
cord-285778-80baxwgc	316	24	and	and	CC
cord-285778-80baxwgc	316	25	deleterious	deleterious	JJ
cord-285778-80baxwgc	316	26	consequences	consequence	NNS
cord-285778-80baxwgc	316	27	for	for	IN
cord-285778-80baxwgc	316	28	the	the	DT
cord-285778-80baxwgc	316	29	transplant	transplant	NN
cord-285778-80baxwgc	316	30	patient	patient	NN
cord-285778-80baxwgc	316	31	.	.	.
cord-285778-80baxwgc	317	1	Secondly	secondly	RB
cord-285778-80baxwgc	317	2	,	,	,
cord-285778-80baxwgc	317	3	when	when	WRB
cord-285778-80baxwgc	317	4	the	the	DT
cord-285778-80baxwgc	317	5	tolerance	tolerance	NN
cord-285778-80baxwgc	317	6	of	of	IN
cord-285778-80baxwgc	317	7	an	an	DT
cord-285778-80baxwgc	317	8	individual	individual	NN
cord-285778-80baxwgc	317	9	's	's	POS
cord-285778-80baxwgc	317	10	adaptive	adaptive	JJ
cord-285778-80baxwgc	317	11	immune	immune	JJ
cord-285778-80baxwgc	317	12	response	response	NN
cord-285778-80baxwgc	317	13	fails	fail	VBZ
cord-285778-80baxwgc	317	14	,	,	,
cord-285778-80baxwgc	317	15	self	self	NN
cord-285778-80baxwgc	317	16	tissues	tissue	NNS
cord-285778-80baxwgc	317	17	are	be	VBP
cord-285778-80baxwgc	317	18	attacked	attack	VBN
cord-285778-80baxwgc	317	19	in	in	IN
cord-285778-80baxwgc	317	20	a	a	DT
cord-285778-80baxwgc	317	21	way	way	NN
cord-285778-80baxwgc	317	22	that	that	WDT
cord-285778-80baxwgc	317	23	can	can	MD
cord-285778-80baxwgc	317	24	lead	lead	VB
cord-285778-80baxwgc	317	25	to	to	IN
cord-285778-80baxwgc	317	26	autoimmune	autoimmune	JJ
cord-285778-80baxwgc	317	27	disease	disease	NN
cord-285778-80baxwgc	317	28	.	.	.
cord-285778-80baxwgc	318	1	Thirdly	thirdly	RB
cord-285778-80baxwgc	318	2	,	,	,
cord-285778-80baxwgc	318	3	an	an	DT
cord-285778-80baxwgc	318	4	immune	immune	JJ
cord-285778-80baxwgc	318	5	response	response	NN
cord-285778-80baxwgc	318	6	that	that	WDT
cord-285778-80baxwgc	318	7	is	be	VBZ
cord-285778-80baxwgc	318	8	too	too	RB
cord-285778-80baxwgc	318	9	strong	strong	JJ
cord-285778-80baxwgc	318	10	or	or	CC
cord-285778-80baxwgc	318	11	long	long	RB
cord-285778-80baxwgc	318	12	can	can	MD
cord-285778-80baxwgc	318	13	result	result	VB
cord-285778-80baxwgc	318	14	in	in	IN
cord-285778-80baxwgc	318	15	hypersensitivity	hypersensitivity	NN
cord-285778-80baxwgc	318	16	to	to	IN
cord-285778-80baxwgc	318	17	an	an	DT
cord-285778-80baxwgc	318	18	entity	entity	NN
cord-285778-80baxwgc	318	19	.	.	.
cord-285778-80baxwgc	319	1	In	in	IN
cord-285778-80baxwgc	319	2	this	this	DT
cord-285778-80baxwgc	319	3	situation	situation	NN
cord-285778-80baxwgc	319	4	,	,	,
cord-285778-80baxwgc	319	5	the	the	DT
cord-285778-80baxwgc	319	6	normal	normal	JJ
cord-285778-80baxwgc	319	7	inflammation	inflammation	NN
cord-285778-80baxwgc	319	8	that	that	WDT
cord-285778-80baxwgc	319	9	accompanies	accompany	VBZ
cord-285778-80baxwgc	319	10	the	the	DT
cord-285778-80baxwgc	319	11	response	response	NN
cord-285778-80baxwgc	319	12	gets	get	VBZ
cord-285778-80baxwgc	319	13	out	out	IN
cord-285778-80baxwgc	319	14	of	of	IN
cord-285778-80baxwgc	319	15	control	control	NN
cord-285778-80baxwgc	319	16	and	and	CC
cord-285778-80baxwgc	319	17	causes	cause	VBZ
cord-285778-80baxwgc	319	18	significant	significant	JJ
cord-285778-80baxwgc	319	19	collateral	collateral	JJ
cord-285778-80baxwgc	319	20	tissue	tissue	NN
cord-285778-80baxwgc	319	21	damage	damage	NN
cord-285778-80baxwgc	319	22	.	.	.
cord-285778-80baxwgc	320	1	When	when	WRB
cord-285778-80baxwgc	320	2	an	an	DT
cord-285778-80baxwgc	320	3	individual	individual	NN
cord-285778-80baxwgc	320	4	's	's	POS
cord-285778-80baxwgc	320	5	normal	normal	JJ
cord-285778-80baxwgc	320	6	adaptive	adaptive	JJ
cord-285778-80baxwgc	320	7	immune	immune	JJ
cord-285778-80baxwgc	320	8	system	system	NN
cord-285778-80baxwgc	320	9	responds	respond	VBZ
cord-285778-80baxwgc	320	10	inappropriately	inappropriately	RB
cord-285778-80baxwgc	320	11	to	to	IN
cord-285778-80baxwgc	320	12	an	an	DT
cord-285778-80baxwgc	320	13	antigen	antigen	NN
cord-285778-80baxwgc	320	14	that	that	WDT
cord-285778-80baxwgc	320	15	is	be	VBZ
cord-285778-80baxwgc	320	16	generally	generally	RB
cord-285778-80baxwgc	320	17	harmless	harmless	JJ
cord-285778-80baxwgc	320	18	,	,	,
cord-285778-80baxwgc	320	19	the	the	DT
cord-285778-80baxwgc	320	20	immune	immune	JJ
cord-285778-80baxwgc	320	21	response	response	NN
cord-285778-80baxwgc	320	22	is	be	VBZ
cord-285778-80baxwgc	320	23	manifested	manifest	VBN
cord-285778-80baxwgc	320	24	clinically	clinically	RB
cord-285778-80baxwgc	320	25	as	as	IN
cord-285778-80baxwgc	320	26	a	a	DT
cord-285778-80baxwgc	320	27	form	form	NN
cord-285778-80baxwgc	320	28	of	of	IN
cord-285778-80baxwgc	320	29	hypersensitivity	hypersensitivity	NN
cord-285778-80baxwgc	320	30	called	call	VBD
cord-285778-80baxwgc	320	31	allergy	allergy	NN
cord-285778-80baxwgc	320	32	.	.	.
cord-285778-80baxwgc	321	1	Lastly	lastly	RB
cord-285778-80baxwgc	321	2	,	,	,
cord-285778-80baxwgc	321	3	if	if	IN
cord-285778-80baxwgc	321	4	normal	normal	JJ
cord-285778-80baxwgc	321	5	regulation	regulation	NN
cord-285778-80baxwgc	321	6	of	of	IN
cord-285778-80baxwgc	321	7	the	the	DT
cord-285778-80baxwgc	321	8	inflammatory	inflammatory	JJ
cord-285778-80baxwgc	321	9	response	response	NN
cord-285778-80baxwgc	321	10	is	be	VBZ
cord-285778-80baxwgc	321	11	lost	lose	VBN
cord-285778-80baxwgc	321	12	for	for	IN
cord-285778-80baxwgc	321	13	an	an	DT
cord-285778-80baxwgc	321	14	extended	extended	JJ
cord-285778-80baxwgc	321	15	period	period	NN
cord-285778-80baxwgc	321	16	for	for	IN
cord-285778-80baxwgc	321	17	any	any	DT
cord-285778-80baxwgc	321	18	reason	reason	NN
cord-285778-80baxwgc	321	19	,	,	,
cord-285778-80baxwgc	321	20	chronic	chronic	JJ
cord-285778-80baxwgc	321	21	inflammation	inflammation	NN
cord-285778-80baxwgc	321	22	ensues	ensue	VBZ
cord-285778-80baxwgc	321	23	that	that	WDT
cord-285778-80baxwgc	321	24	can	can	MD
cord-285778-80baxwgc	321	25	set	set	VB
cord-285778-80baxwgc	321	26	up	up	RP
cord-285778-80baxwgc	321	27	conditions	condition	NNS
cord-285778-80baxwgc	321	28	allowing	allow	VBG
cord-285778-80baxwgc	321	29	the	the	DT
cord-285778-80baxwgc	321	30	development	development	NN
cord-285778-80baxwgc	321	31	of	of	IN
cord-285778-80baxwgc	321	32	tumors	tumor	NNS
cord-285778-80baxwgc	321	33	,	,	,
cord-285778-80baxwgc	321	34	heart	heart	NN
cord-285778-80baxwgc	321	35	disease	disease	NN
cord-285778-80baxwgc	321	36	or	or	CC
cord-285778-80baxwgc	321	37	autoimmune	autoimmune	JJ
cord-285778-80baxwgc	321	38	disorders	disorder	NNS
cord-285778-80baxwgc	321	39	.	.	.
cord-285778-80baxwgc	322	1	The	the	DT
cord-285778-80baxwgc	322	2	remainder	remainder	NN
cord-285778-80baxwgc	322	3	of	of	IN
cord-285778-80baxwgc	322	4	this	this	DT
cord-285778-80baxwgc	322	5	book	book	NN
cord-285778-80baxwgc	322	6	will	will	MD
cord-285778-80baxwgc	322	7	take	take	VB
cord-285778-80baxwgc	322	8	the	the	DT
cord-285778-80baxwgc	322	9	reader	reader	NN
cord-285778-80baxwgc	322	10	on	on	IN
cord-285778-80baxwgc	322	11	a	a	DT
cord-285778-80baxwgc	322	12	logical	logical	JJ
cord-285778-80baxwgc	322	13	tour	tour	NN
cord-285778-80baxwgc	322	14	of	of	IN
cord-285778-80baxwgc	322	15	the	the	DT
cord-285778-80baxwgc	322	16	immune	immune	JJ
cord-285778-80baxwgc	322	17	response	response	NN
cord-285778-80baxwgc	322	18	.	.	.
cord-285778-80baxwgc	323	1	Chapter	chapter	NN
cord-285778-80baxwgc	323	2	2	2	CD
cord-285778-80baxwgc	323	3	continues	continue	VBZ
cord-285778-80baxwgc	323	4	our	-PRON-	PRP$
cord-285778-80baxwgc	323	5	Basic	Basic	NNP
cord-285778-80baxwgc	323	6	Immunology	Immunology	NNP
cord-285778-80baxwgc	323	7	section	section	NN
cord-285778-80baxwgc	323	8	,	,	,
cord-285778-80baxwgc	323	9	providing	provide	VBG
cord-285778-80baxwgc	323	10	detailed	detailed	JJ
cord-285778-80baxwgc	323	11	descriptions	description	NNS
cord-285778-80baxwgc	323	12	of	of	IN
cord-285778-80baxwgc	323	13	the	the	DT
cord-285778-80baxwgc	323	14	various	various	JJ
cord-285778-80baxwgc	323	15	cells	cell	NNS
cord-285778-80baxwgc	323	16	,	,	,
cord-285778-80baxwgc	323	17	tissues	tissue	NNS
cord-285778-80baxwgc	323	18	and	and	CC
cord-285778-80baxwgc	323	19	cytokines	cytokine	NNS
cord-285778-80baxwgc	323	20	involved	involve	VBN
cord-285778-80baxwgc	323	21	in	in	IN
cord-285778-80baxwgc	323	22	mediating	mediate	VBG
cord-285778-80baxwgc	323	23	immune	immune	JJ
cord-285778-80baxwgc	323	24	responses	response	NNS
cord-285778-80baxwgc	323	25	.	.	.
cord-285778-80baxwgc	324	1	Chapters	chapter	NNS
cord-285778-80baxwgc	324	2	3	3	CD
cord-285778-80baxwgc	324	3	-	-	SYM
cord-285778-80baxwgc	324	4	12	12	CD
cord-285778-80baxwgc	324	5	cover	cover	NN
cord-285778-80baxwgc	324	6	all	all	DT
cord-285778-80baxwgc	324	7	aspects	aspect	NNS
cord-285778-80baxwgc	324	8	of	of	IN
cord-285778-80baxwgc	324	9	the	the	DT
cord-285778-80baxwgc	324	10	innate	innate	JJ
cord-285778-80baxwgc	324	11	and	and	CC
cord-285778-80baxwgc	324	12	adaptive	adaptive	JJ
cord-285778-80baxwgc	324	13	immune	immune	JJ
cord-285778-80baxwgc	324	14	responses	response	NNS
cord-285778-80baxwgc	324	15	in	in	IN
cord-285778-80baxwgc	324	16	depth	depth	NN
cord-285778-80baxwgc	324	17	.	.	.
cord-285778-80baxwgc	325	1	The	the	DT
cord-285778-80baxwgc	325	2	chapters	chapter	NNS
cord-285778-80baxwgc	325	3	in	in	IN
cord-285778-80baxwgc	325	4	our	-PRON-	PRP$
cord-285778-80baxwgc	325	5	Clinical	Clinical	NNP
cord-285778-80baxwgc	325	6	Immunology	Immunology	NNP
cord-285778-80baxwgc	325	7	section	section	NN
cord-285778-80baxwgc	325	8	,	,	,
cord-285778-80baxwgc	325	9	Chapters	Chapters	NNPS
cord-285778-80baxwgc	325	10	13	13	CD
cord-285778-80baxwgc	325	11	-	-	SYM
cord-285778-80baxwgc	325	12	20	20	CD
cord-285778-80baxwgc	325	13	,	,	,
cord-285778-80baxwgc	325	14	address	address	VB
cord-285778-80baxwgc	325	15	immunological	immunological	JJ
cord-285778-80baxwgc	325	16	principles	principle	NNS
cord-285778-80baxwgc	325	17	not	not	RB
cord-285778-80baxwgc	325	18	only	only	RB
cord-285778-80baxwgc	325	19	of	of	IN
cord-285778-80baxwgc	325	20	practical	practical	JJ
cord-285778-80baxwgc	325	21	value	value	NN
cord-285778-80baxwgc	325	22	to	to	IN
cord-285778-80baxwgc	325	23	the	the	DT
cord-285778-80baxwgc	325	24	more	more	RBR
cord-285778-80baxwgc	325	25	medically	medically	RB
cord-285778-80baxwgc	325	26	oriented	orient	VBN
cord-285778-80baxwgc	325	27	reader	reader	NN
cord-285778-80baxwgc	325	28	but	but	CC
cord-285778-80baxwgc	325	29	also	also	RB
cord-285778-80baxwgc	325	30	of	of	IN
cord-285778-80baxwgc	325	31	interest	interest	NN
cord-285778-80baxwgc	325	32	to	to	IN
cord-285778-80baxwgc	325	33	all	all	DT
cord-285778-80baxwgc	325	34	who	who	WP
cord-285778-80baxwgc	325	35	seek	seek	VBP
cord-285778-80baxwgc	325	36	to	to	TO
cord-285778-80baxwgc	325	37	understand	understand	VB
cord-285778-80baxwgc	325	38	the	the	DT
cord-285778-80baxwgc	325	39	pivotal	pivotal	JJ
cord-285778-80baxwgc	325	40	role	role	NN
cord-285778-80baxwgc	325	41	of	of	IN
cord-285778-80baxwgc	325	42	the	the	DT
cord-285778-80baxwgc	325	43	immune	immune	JJ
cord-285778-80baxwgc	325	44	system	system	NN
cord-285778-80baxwgc	325	45	in	in	IN
cord-285778-80baxwgc	325	46	health	health	NN
cord-285778-80baxwgc	325	47	and	and	CC
cord-285778-80baxwgc	325	48	disease	disease	NN
cord-285778-80baxwgc	325	49	.	.	.
cord-285778-80baxwgc	326	1	It	-PRON-	PRP
cord-285778-80baxwgc	326	2	is	be	VBZ
cord-285778-80baxwgc	326	3	our	-PRON-	PRP$
cord-285778-80baxwgc	326	4	hope	hope	NN
cord-285778-80baxwgc	326	5	that	that	IN
cord-285778-80baxwgc	326	6	the	the	DT
cord-285778-80baxwgc	326	7	reader	reader	NN
cord-285778-80baxwgc	326	8	will	will	MD
cord-285778-80baxwgc	326	9	come	come	VB
cord-285778-80baxwgc	326	10	away	away	RB
cord-285778-80baxwgc	326	11	with	with	IN
cord-285778-80baxwgc	326	12	a	a	DT
cord-285778-80baxwgc	326	13	solid	solid	JJ
cord-285778-80baxwgc	326	14	understanding	understanding	NN
cord-285778-80baxwgc	326	15	of	of	IN
cord-285778-80baxwgc	326	16	the	the	DT
cord-285778-80baxwgc	326	17	cellular	cellular	JJ
cord-285778-80baxwgc	326	18	and	and	CC
cord-285778-80baxwgc	326	19	molecular	molecular	JJ
cord-285778-80baxwgc	326	20	mechanisms	mechanism	NNS
cord-285778-80baxwgc	326	21	underlying	underlie	VBG
cord-285778-80baxwgc	326	22	immunity	immunity	NN
cord-285778-80baxwgc	326	23	and	and	CC
cord-285778-80baxwgc	326	24	how	how	WRB
cord-285778-80baxwgc	326	25	these	these	DT
cord-285778-80baxwgc	326	26	mechanisms	mechanism	NNS
cord-285778-80baxwgc	326	27	can	can	MD
cord-285778-80baxwgc	326	28	go	go	VB
cord-285778-80baxwgc	326	29	awry	awry	JJ
cord-285778-80baxwgc	326	30	to	to	TO
cord-285778-80baxwgc	326	31	cause	cause	VB
cord-285778-80baxwgc	326	32	illness	illness	NN
cord-285778-80baxwgc	326	33	.	.	.
cord-285778-80baxwgc	327	1	We	-PRON-	PRP
cord-285778-80baxwgc	327	2	also	also	RB
cord-285778-80baxwgc	327	3	provide	provide	VBP
cord-285778-80baxwgc	327	4	a	a	DT
cord-285778-80baxwgc	327	5	glimpse	glimpse	NN
cord-285778-80baxwgc	327	6	of	of	IN
cord-285778-80baxwgc	327	7	how	how	WRB
cord-285778-80baxwgc	327	8	researchers	researcher	NNS
cord-285778-80baxwgc	327	9	seek	seek	VBP
cord-285778-80baxwgc	327	10	to	to	TO
cord-285778-80baxwgc	327	11	manipulate	manipulate	VB
cord-285778-80baxwgc	327	12	these	these	DT
cord-285778-80baxwgc	327	13	mechanisms	mechanism	NNS
cord-285778-80baxwgc	327	14	with	with	IN
cord-285778-80baxwgc	327	15	the	the	DT
cord-285778-80baxwgc	327	16	goal	goal	NN
cord-285778-80baxwgc	327	17	of	of	IN
cord-285778-80baxwgc	327	18	ensuring	ensure	VBG
cord-285778-80baxwgc	327	19	good	good	JJ
cord-285778-80baxwgc	327	20	health	health	NN
cord-285778-80baxwgc	327	21	for	for	IN
cord-285778-80baxwgc	327	22	all	all	DT
cord-285778-80baxwgc	327	23	.	.	.
cord-285778-80baxwgc	328	1	The	the	DT
cord-285778-80baxwgc	328	2	pathological	pathological	JJ
cord-285778-80baxwgc	328	3	consequences	consequence	NNS
cord-285778-80baxwgc	328	4	of	of	IN
cord-285778-80baxwgc	328	5	immune	immune	JJ
cord-285778-80baxwgc	328	6	system	system	NN
cord-285778-80baxwgc	328	7	irregularities	irregularity	NNS
cord-285778-80baxwgc	328	8	include	include	VBP
cord-285778-80baxwgc	328	9	immunodeficiency	immunodeficiency	NN
cord-285778-80baxwgc	328	10	(	(	-LRB-
cord-285778-80baxwgc	328	11	Ch	Ch	NNP
cord-285778-80baxwgc	328	12	.	.	NNP
cord-285778-80baxwgc	328	13	15	15	CD
cord-285778-80baxwgc	328	14	)	)	-RRB-
cord-285778-80baxwgc	328	15	,	,	,
cord-285778-80baxwgc	328	16	cancer	cancer	NN
cord-285778-80baxwgc	328	17	(	(	-LRB-
cord-285778-80baxwgc	328	18	Ch	Ch	NNP
cord-285778-80baxwgc	328	19	.	.	.
cord-285778-80baxwgc	329	1	16	16	CD
cord-285778-80baxwgc	329	2	and	and	CC
cord-285778-80baxwgc	329	3	20	20	CD
cord-285778-80baxwgc	329	4	)	)	-RRB-
cord-285778-80baxwgc	329	5	,	,	,
cord-285778-80baxwgc	329	6	transplant	transplant	NN
cord-285778-80baxwgc	329	7	rejection	rejection	NN
cord-285778-80baxwgc	329	8	(	(	-LRB-
cord-285778-80baxwgc	329	9	Ch	Ch	NNP
cord-285778-80baxwgc	329	10	.	.	NNP
cord-285778-80baxwgc	329	11	17	17	CD
cord-285778-80baxwgc	329	12	)	)	-RRB-
cord-285778-80baxwgc	329	13	,	,	,
cord-285778-80baxwgc	329	14	hypersensitivity	hypersensitivity	NN
cord-285778-80baxwgc	329	15	(	(	-LRB-
cord-285778-80baxwgc	329	16	Ch	Ch	NNP
cord-285778-80baxwgc	329	17	.	.	NNP
cord-285778-80baxwgc	329	18	18	18	CD
cord-285778-80baxwgc	329	19	)	)	-RRB-
cord-285778-80baxwgc	329	20	and	and	CC
cord-285778-80baxwgc	329	21	autoimmune	autoimmune	JJ
cord-285778-80baxwgc	329	22	disease	disease	NN
cord-285778-80baxwgc	329	23	(	(	-LRB-
cord-285778-80baxwgc	329	24	Ch	Ch	NNP
cord-285778-80baxwgc	329	25	.	.	NNP
cord-285778-80baxwgc	329	26	19	19	CD
cord-285778-80baxwgc	329	27	)	)	-RRB-
cord-285778-80baxwgc	329	28	.	.	.
cord-285778-80baxwgc	330	1	The	the	DT
cord-285778-80baxwgc	330	2	way	way	NN
cord-285778-80baxwgc	330	3	in	in	IN
cord-285778-80baxwgc	330	4	which	which	WDT
cord-285778-80baxwgc	330	5	the	the	DT
cord-285778-80baxwgc	330	6	immune	immune	JJ
cord-285778-80baxwgc	330	7	system	system	NN
cord-285778-80baxwgc	330	8	responds	respond	VBZ
cord-285778-80baxwgc	330	9	can	can	MD
cord-285778-80baxwgc	330	10	maintain	maintain	VB
cord-285778-80baxwgc	330	11	a	a	DT
cord-285778-80baxwgc	330	12	healthy	healthy	JJ
cord-285778-80baxwgc	330	13	body	body	NN
cord-285778-80baxwgc	330	14	or	or	CC
cord-285778-80baxwgc	330	15	lead	lead	NN
cord-285778-80baxwgc	330	16	to	to	IN
cord-285778-80baxwgc	330	17	disease	disease	NN
cord-285778-80baxwgc	330	18	.	.	.
cord-285778-80baxwgc	331	1	In	in	IN
cord-285778-80baxwgc	331	2	a	a	DT
cord-285778-80baxwgc	331	3	healthy	healthy	JJ
cord-285778-80baxwgc	331	4	individual	individual	NN
cord-285778-80baxwgc	331	5	,	,	,
cord-285778-80baxwgc	331	6	the	the	DT
cord-285778-80baxwgc	331	7	immune	immune	JJ
cord-285778-80baxwgc	331	8	system	system	NN
cord-285778-80baxwgc	331	9	mounts	mount	VBZ
cord-285778-80baxwgc	331	10	an	an	DT
cord-285778-80baxwgc	331	11	appropriate	appropriate	JJ
cord-285778-80baxwgc	331	12	response	response	NN
cord-285778-80baxwgc	331	13	that	that	WDT
cord-285778-80baxwgc	331	14	clears	clear	VBZ
cord-285778-80baxwgc	331	15	damaged	damaged	JJ
cord-285778-80baxwgc	331	16	cells	cell	NNS
cord-285778-80baxwgc	331	17	and	and	CC
cord-285778-80baxwgc	331	18	kills	kill	VBZ
cord-285778-80baxwgc	331	19	infectious	infectious	JJ
cord-285778-80baxwgc	331	20	organisms	organism	NNS
cord-285778-80baxwgc	331	21	or	or	CC
cord-285778-80baxwgc	331	22	cancerous	cancerous	JJ
cord-285778-80baxwgc	331	23	cells	cell	NNS
cord-285778-80baxwgc	331	24	.	.	.
cord-285778-80baxwgc	332	1	However	however	RB
cord-285778-80baxwgc	332	2	,	,	,
cord-285778-80baxwgc	332	3	the	the	DT
cord-285778-80baxwgc	332	4	immune	immune	JJ
cord-285778-80baxwgc	332	5	system	system	NN
cord-285778-80baxwgc	332	6	is	be	VBZ
cord-285778-80baxwgc	332	7	a	a	DT
cord-285778-80baxwgc	332	8	powerful	powerful	JJ
cord-285778-80baxwgc	332	9	and	and	CC
cord-285778-80baxwgc	332	10	multi	multi	JJ
cord-285778-80baxwgc	332	11	-	-	JJ
cord-285778-80baxwgc	332	12	faceted	faceted	JJ
cord-285778-80baxwgc	332	13	weapon	weapon	NN
cord-285778-80baxwgc	332	14	that	that	WDT
cord-285778-80baxwgc	332	15	requires	require	VBZ
cord-285778-80baxwgc	332	16	strict	strict	JJ
cord-285778-80baxwgc	332	17	controls	control	NNS
cord-285778-80baxwgc	332	18	to	to	TO
cord-285778-80baxwgc	332	19	remain	remain	VB
cord-285778-80baxwgc	332	20	in	in	IN
cord-285778-80baxwgc	332	21	balance	balance	NN
cord-285778-80baxwgc	332	22	.	.	.
cord-285778-80baxwgc	333	1	When	when	WRB
cord-285778-80baxwgc	333	2	the	the	DT
cord-285778-80baxwgc	333	3	immune	immune	JJ
cord-285778-80baxwgc	333	4	system	system	NN
cord-285778-80baxwgc	333	5	fails	fail	VBZ
cord-285778-80baxwgc	333	6	to	to	TO
cord-285778-80baxwgc	333	7	respond	respond	VB
cord-285778-80baxwgc	333	8	adequately	adequately	RB
cord-285778-80baxwgc	333	9	,	,	,
cord-285778-80baxwgc	333	10	or	or	CC
cord-285778-80baxwgc	333	11	mounts	mount	VBZ
cord-285778-80baxwgc	333	12	an	an	DT
cord-285778-80baxwgc	333	13	overzealous	overzealous	JJ
cord-285778-80baxwgc	333	14	or	or	CC
cord-285778-80baxwgc	333	15	inappropriate	inappropriate	JJ
cord-285778-80baxwgc	333	16	attack	attack	NN
cord-285778-80baxwgc	333	17	,	,	,
cord-285778-80baxwgc	333	18	or	or	CC
cord-285778-80baxwgc	333	19	ignores	ignore	VBZ
cord-285778-80baxwgc	333	20	normal	normal	JJ
cord-285778-80baxwgc	333	21	control	control	NN
cord-285778-80baxwgc	333	22	mechanisms	mechanism	NNS
cord-285778-80baxwgc	333	23	,	,	,
cord-285778-80baxwgc	333	24	a	a	DT
cord-285778-80baxwgc	333	25	wide	wide	JJ
cord-285778-80baxwgc	333	26	variety	variety	NN
cord-285778-80baxwgc	333	27	of	of	IN
cord-285778-80baxwgc	333	28	disease	disease	NN
cord-285778-80baxwgc	333	29	states	state	NNS
cord-285778-80baxwgc	333	30	can	can	MD
cord-285778-80baxwgc	333	31	result	result	VB
cord-285778-80baxwgc	333	32	.	.	.
cord-285778-80baxwgc	334	1	Immunodeficiency	Immunodeficiency	NNP
cord-285778-80baxwgc	334	2	Autoimmune	Autoimmune	NNP
cord-285778-80baxwgc	334	3	disease	disease	NN
cord-285778-80baxwgc	334	4	Hypersensitivity	hypersensitivity	NN
cord-285778-80baxwgc	334	5	and	and	CC
cord-285778-80baxwgc	334	6	allergy	allergy	NN
cord-285778-80baxwgc	334	7	Destruction	destruction	NN
cord-285778-80baxwgc	334	8	of	of	IN
cord-285778-80baxwgc	334	9	cancer	cancer	NN
cord-285778-80baxwgc	334	10	cells	cell	NNS
cord-285778-80baxwgc	335	1	•	•	NNP
cord-285778-80baxwgc	336	1	The	the	DT
cord-285778-80baxwgc	336	2	immune	immune	JJ
cord-285778-80baxwgc	336	3	system	system	NN
cord-285778-80baxwgc	336	4	is	be	VBZ
cord-285778-80baxwgc	336	5	a	a	DT
cord-285778-80baxwgc	336	6	central	central	JJ
cord-285778-80baxwgc	336	7	player	player	NN
cord-285778-80baxwgc	336	8	in	in	IN
cord-285778-80baxwgc	336	9	the	the	DT
cord-285778-80baxwgc	336	10	maintenance	maintenance	NN
cord-285778-80baxwgc	336	11	of	of	IN
cord-285778-80baxwgc	336	12	human	human	JJ
cord-285778-80baxwgc	336	13	health	health	NN
cord-285778-80baxwgc	336	14	.	.	.
cord-285778-80baxwgc	337	1	•	•	NNP
cord-285778-80baxwgc	338	1	Immune	immune	JJ
cord-285778-80baxwgc	338	2	responses	response	NNS
cord-285778-80baxwgc	338	3	depend	depend	VBP
cord-285778-80baxwgc	338	4	on	on	IN
cord-285778-80baxwgc	338	5	the	the	DT
cord-285778-80baxwgc	338	6	coordinated	coordinated	JJ
cord-285778-80baxwgc	338	7	action	action	NN
cord-285778-80baxwgc	338	8	of	of	IN
cord-285778-80baxwgc	338	9	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	338	10	that	that	WDT
cord-285778-80baxwgc	338	11	travel	travel	VBP
cord-285778-80baxwgc	338	12	throughout	throughout	IN
cord-285778-80baxwgc	338	13	the	the	DT
cord-285778-80baxwgc	338	14	body	body	NN
cord-285778-80baxwgc	338	15	to	to	TO
cord-285778-80baxwgc	338	16	recognize	recognize	VB
cord-285778-80baxwgc	338	17	and	and	CC
cord-285778-80baxwgc	338	18	eliminate	eliminate	VB
cord-285778-80baxwgc	338	19	threats	threat	NNS
cord-285778-80baxwgc	338	20	posed	pose	VBN
cord-285778-80baxwgc	338	21	by	by	IN
cord-285778-80baxwgc	338	22	trauma	trauma	NN
cord-285778-80baxwgc	338	23	as	as	RB
cord-285778-80baxwgc	338	24	well	well	RB
cord-285778-80baxwgc	338	25	as	as	IN
cord-285778-80baxwgc	338	26	by	by	IN
cord-285778-80baxwgc	338	27	extracellular	extracellular	JJ
cord-285778-80baxwgc	338	28	and	and	CC
cord-285778-80baxwgc	338	29	intracellular	intracellular	JJ
cord-285778-80baxwgc	338	30	pathogens	pathogen	NNS
cord-285778-80baxwgc	338	31	,	,	,
cord-285778-80baxwgc	338	32	toxins	toxin	NNS
cord-285778-80baxwgc	338	33	and	and	CC
cord-285778-80baxwgc	338	34	cancerous	cancerous	JJ
cord-285778-80baxwgc	338	35	cells	cell	NNS
cord-285778-80baxwgc	338	36	.	.	.
cord-285778-80baxwgc	339	1	•	•	NNP
cord-285778-80baxwgc	340	1	Cytokines	cytokine	NNS
cord-285778-80baxwgc	340	2	are	be	VBP
cord-285778-80baxwgc	340	3	secreted	secrete	VBN
cord-285778-80baxwgc	340	4	intercellular	intercellular	JJ
cord-285778-80baxwgc	340	5	messenger	messenger	NN
cord-285778-80baxwgc	340	6	proteins	protein	NNS
cord-285778-80baxwgc	340	7	that	that	WDT
cord-285778-80baxwgc	340	8	mediate	mediate	VBP
cord-285778-80baxwgc	340	9	complex	complex	JJ
cord-285778-80baxwgc	340	10	interactions	interaction	NNS
cord-285778-80baxwgc	340	11	among	among	IN
cord-285778-80baxwgc	340	12	leukocytes	leukocyte	NNS
cord-285778-80baxwgc	340	13	.	.	.
cord-285778-80baxwgc	341	1	•	•	NNP
cord-285778-80baxwgc	342	1	Complete	complete	JJ
cord-285778-80baxwgc	342	2	protection	protection	NN
cord-285778-80baxwgc	342	3	from	from	IN
cord-285778-80baxwgc	342	4	and	and	CC
cord-285778-80baxwgc	342	5	clearance	clearance	NN
cord-285778-80baxwgc	342	6	of	of	IN
cord-285778-80baxwgc	342	7	unwanted	unwanted	JJ
cord-285778-80baxwgc	342	8	entities	entity	NNS
cord-285778-80baxwgc	342	9	often	often	RB
cord-285778-80baxwgc	342	10	involve	involve	VBP
cord-285778-80baxwgc	342	11	both	both	DT
cord-285778-80baxwgc	342	12	innate	innate	JJ
cord-285778-80baxwgc	342	13	and	and	CC
cord-285778-80baxwgc	342	14	adaptive	adaptive	JJ
cord-285778-80baxwgc	342	15	responses	response	NNS
cord-285778-80baxwgc	342	16	.	.	.
cord-285778-80baxwgc	343	1	•	•	NNP
cord-285778-80baxwgc	344	1	Some	some	DT
cord-285778-80baxwgc	344	2	innate	innate	JJ
cord-285778-80baxwgc	344	3	mechanisms	mechanism	NNS
cord-285778-80baxwgc	344	4	require	require	VBP
cord-285778-80baxwgc	344	5	no	no	DT
cord-285778-80baxwgc	344	6	induction	induction	NN
cord-285778-80baxwgc	344	7	and	and	CC
cord-285778-80baxwgc	344	8	are	be	VBP
cord-285778-80baxwgc	344	9	completely	completely	RB
cord-285778-80baxwgc	344	10	non	non	JJ
cord-285778-80baxwgc	344	11	-	-	JJ
cord-285778-80baxwgc	344	12	specific	specific	JJ
cord-285778-80baxwgc	344	13	,	,	,
cord-285778-80baxwgc	344	14	whereas	whereas	IN
cord-285778-80baxwgc	344	15	others	other	NNS
cord-285778-80baxwgc	344	16	are	be	VBP
cord-285778-80baxwgc	344	17	inducible	inducible	JJ
cord-285778-80baxwgc	344	18	and	and	CC
cord-285778-80baxwgc	344	19	involve	involve	VBP
cord-285778-80baxwgc	344	20	broad	broad	JJ
cord-285778-80baxwgc	344	21	recognition	recognition	NN
cord-285778-80baxwgc	344	22	of	of	IN
cord-285778-80baxwgc	344	23	a	a	DT
cord-285778-80baxwgc	344	24	limited	limited	JJ
cord-285778-80baxwgc	344	25	number	number	NN
cord-285778-80baxwgc	344	26	of	of	IN
cord-285778-80baxwgc	344	27	molecular	molecular	JJ
cord-285778-80baxwgc	344	28	patterns	pattern	NNS
cord-285778-80baxwgc	344	29	(	(	-LRB-
cord-285778-80baxwgc	344	30	PAMPS	pamps	NN
cord-285778-80baxwgc	344	31	and	and	CC
cord-285778-80baxwgc	344	32	DAMPs	damp	NNS
cord-285778-80baxwgc	344	33	)	)	-RRB-
cord-285778-80baxwgc	344	34	by	by	IN
cord-285778-80baxwgc	344	35	PRMs	prm	NNS
cord-285778-80baxwgc	344	36	.	.	.
cord-285778-80baxwgc	345	1	•	•	NNP
cord-285778-80baxwgc	346	1	Adaptive	adaptive	JJ
cord-285778-80baxwgc	346	2	responses	response	NNS
cord-285778-80baxwgc	346	3	are	be	VBP
cord-285778-80baxwgc	346	4	mounted	mount	VBN
cord-285778-80baxwgc	346	5	after	after	IN
cord-285778-80baxwgc	346	6	innate	innate	JJ
cord-285778-80baxwgc	346	7	responses	response	NNS
cord-285778-80baxwgc	346	8	have	have	VBP
cord-285778-80baxwgc	346	9	failed	fail	VBN
cord-285778-80baxwgc	346	10	to	to	TO
cord-285778-80baxwgc	346	11	remove	remove	VB
cord-285778-80baxwgc	346	12	an	an	DT
cord-285778-80baxwgc	346	13	unwanted	unwanted	JJ
cord-285778-80baxwgc	346	14	entity	entity	NN
cord-285778-80baxwgc	346	15	,	,	,
cord-285778-80baxwgc	346	16	and	and	CC
cord-285778-80baxwgc	346	17	are	be	VBP
cord-285778-80baxwgc	346	18	dependent	dependent	JJ
cord-285778-80baxwgc	346	19	on	on	IN
cord-285778-80baxwgc	346	20	cytokines	cytokine	NNS
cord-285778-80baxwgc	346	21	produced	produce	VBN
cord-285778-80baxwgc	346	22	during	during	IN
cord-285778-80baxwgc	346	23	the	the	DT
cord-285778-80baxwgc	346	24	innate	innate	JJ
cord-285778-80baxwgc	346	25	response	response	NN
cord-285778-80baxwgc	346	26	.	.	.
cord-285778-80baxwgc	347	1	•	•	NNP
cord-285778-80baxwgc	348	1	Adaptive	adaptive	JJ
cord-285778-80baxwgc	348	2	immunity	immunity	NN
cord-285778-80baxwgc	348	3	involves	involve	VBZ
cord-285778-80baxwgc	348	4	the	the	DT
cord-285778-80baxwgc	348	5	selective	selective	JJ
cord-285778-80baxwgc	348	6	activation	activation	NN
cord-285778-80baxwgc	348	7	of	of	IN
cord-285778-80baxwgc	348	8	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	348	9	by	by	IN
cord-285778-80baxwgc	348	10	the	the	DT
cord-285778-80baxwgc	348	11	engagement	engagement	NN
cord-285778-80baxwgc	348	12	of	of	IN
cord-285778-80baxwgc	348	13	their	-PRON-	PRP$
cord-285778-80baxwgc	348	14	antigen	antigen	NN
cord-285778-80baxwgc	348	15	receptors	receptor	NNS
cord-285778-80baxwgc	348	16	by	by	IN
cord-285778-80baxwgc	348	17	antigens	antigen	NNS
cord-285778-80baxwgc	348	18	derived	derive	VBN
cord-285778-80baxwgc	348	19	from	from	IN
cord-285778-80baxwgc	348	20	the	the	DT
cord-285778-80baxwgc	348	21	particular	particular	JJ
cord-285778-80baxwgc	348	22	inciting	incite	VBG
cord-285778-80baxwgc	348	23	entity	entity	NN
cord-285778-80baxwgc	348	24	.	.	.
cord-285778-80baxwgc	349	1	•	•	NNP
cord-285778-80baxwgc	350	1	The	the	DT
cord-285778-80baxwgc	350	2	three	three	CD
cord-285778-80baxwgc	350	3	subsets	subset	NNS
cord-285778-80baxwgc	350	4	of	of	IN
cord-285778-80baxwgc	350	5	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	350	6	are	be	VBP
cord-285778-80baxwgc	350	7	Th	Th	NNP
cord-285778-80baxwgc	350	8	,	,	,
cord-285778-80baxwgc	350	9	Tc	Tc	NNP
cord-285778-80baxwgc	350	10	and	and	CC
cord-285778-80baxwgc	350	11	B	B	NNP
cord-285778-80baxwgc	350	12	cells	cell	NNS
cord-285778-80baxwgc	350	13	,	,	,
cord-285778-80baxwgc	350	14	which	which	WDT
cord-285778-80baxwgc	350	15	use	use	VBP
cord-285778-80baxwgc	350	16	distinct	distinct	JJ
cord-285778-80baxwgc	350	17	mechanisms	mechanism	NNS
cord-285778-80baxwgc	350	18	to	to	TO
cord-285778-80baxwgc	350	19	recognize	recognize	VB
cord-285778-80baxwgc	350	20	antigen	antigen	NN
cord-285778-80baxwgc	350	21	and	and	CC
cord-285778-80baxwgc	350	22	carry	carry	VB
cord-285778-80baxwgc	350	23	out	out	RP
cord-285778-80baxwgc	350	24	effector	effector	NN
cord-285778-80baxwgc	350	25	functions	function	NNS
cord-285778-80baxwgc	350	26	to	to	TO
cord-285778-80baxwgc	350	27	eliminate	eliminate	VB
cord-285778-80baxwgc	350	28	specific	specific	JJ
cord-285778-80baxwgc	350	29	entities	entity	NNS
cord-285778-80baxwgc	350	30	.	.	.
cord-285778-80baxwgc	351	1	•	•	NNP
cord-285778-80baxwgc	352	1	Elements	element	NNS
cord-285778-80baxwgc	352	2	of	of	IN
cord-285778-80baxwgc	352	3	innate	innate	JJ
cord-285778-80baxwgc	352	4	immunity	immunity	NN
cord-285778-80baxwgc	352	5	influence	influence	NN
cord-285778-80baxwgc	352	6	adaptive	adaptive	JJ
cord-285778-80baxwgc	352	7	immunity	immunity	NN
cord-285778-80baxwgc	352	8	and	and	CC
cord-285778-80baxwgc	352	9	vice	vice	NN
cord-285778-80baxwgc	352	10	versa	versa	RB
cord-285778-80baxwgc	352	11	.	.	.
cord-285778-80baxwgc	353	1	•	•	NNP
cord-285778-80baxwgc	354	1	Malfunctions	malfunction	NNS
cord-285778-80baxwgc	354	2	of	of	IN
cord-285778-80baxwgc	354	3	the	the	DT
cord-285778-80baxwgc	354	4	immune	immune	JJ
cord-285778-80baxwgc	354	5	system	system	NN
cord-285778-80baxwgc	354	6	are	be	VBP
cord-285778-80baxwgc	354	7	related	relate	VBN
cord-285778-80baxwgc	354	8	to	to	IN
cord-285778-80baxwgc	354	9	autoimmune	autoimmune	JJ
cord-285778-80baxwgc	354	10	disorders	disorder	NNS
cord-285778-80baxwgc	354	11	,	,	,
cord-285778-80baxwgc	354	12	allergy	allergy	NN
cord-285778-80baxwgc	354	13	and	and	CC
cord-285778-80baxwgc	354	14	other	other	JJ
cord-285778-80baxwgc	354	15	hypersensitivities	hypersensitivity	NNS
cord-285778-80baxwgc	354	16	,	,	,
cord-285778-80baxwgc	354	17	transplantation	transplantation	NN
cord-285778-80baxwgc	354	18	rejection	rejection	NN
cord-285778-80baxwgc	354	19	,	,	,
cord-285778-80baxwgc	354	20	primary	primary	JJ
cord-285778-80baxwgc	354	21	and	and	CC
cord-285778-80baxwgc	354	22	acquired	acquire	VBD
cord-285778-80baxwgc	354	23	immunodeficiencies	immunodeficiency	NNS
cord-285778-80baxwgc	354	24	,	,	,
cord-285778-80baxwgc	354	25	chronic	chronic	JJ
cord-285778-80baxwgc	354	26	inflammation	inflammation	NN
cord-285778-80baxwgc	354	27	,	,	,
cord-285778-80baxwgc	354	28	and	and	CC
cord-285778-80baxwgc	354	29	cancer	cancer	NN
cord-285778-80baxwgc	354	30	development	development	NN
cord-285778-80baxwgc	354	31	.	.	.
cord-285778-80baxwgc	355	1	Section	section	NN
cord-285778-80baxwgc	355	2	A	a	DT
cord-285778-80baxwgc	355	3	1	1	CD
cord-285778-80baxwgc	355	4	)	)	-RRB-
cord-285778-80baxwgc	355	5	Can	Can	MD
cord-285778-80baxwgc	355	6	you	-PRON-	PRP
cord-285778-80baxwgc	355	7	define	define	VB
cord-285778-80baxwgc	355	8	these	these	DT
cord-285778-80baxwgc	355	9	terms	term	NNS
cord-285778-80baxwgc	355	10	?	?	.
cord-285778-80baxwgc	356	1	immunology	immunology	NN
cord-285778-80baxwgc	356	2	,	,	,
cord-285778-80baxwgc	356	3	immune	immune	JJ
cord-285778-80baxwgc	356	4	system	system	NN
cord-285778-80baxwgc	356	5	,	,	,
cord-285778-80baxwgc	356	6	immunity	immunity	NN
cord-285778-80baxwgc	356	7	,	,	,
cord-285778-80baxwgc	356	8	pathogen	pathogen	NN
cord-285778-80baxwgc	356	9	2	2	CD
cord-285778-80baxwgc	356	10	)	)	-RRB-
cord-285778-80baxwgc	357	1	What	what	WP
cord-285778-80baxwgc	357	2	was	be	VBD
cord-285778-80baxwgc	357	3	Koch	Koch	NNP
cord-285778-80baxwgc	357	4	's	's	POS
cord-285778-80baxwgc	357	5	theory	theory	NN
cord-285778-80baxwgc	357	6	and	and	CC
cord-285778-80baxwgc	357	7	why	why	WRB
cord-285778-80baxwgc	357	8	was	be	VBD
cord-285778-80baxwgc	357	9	it	-PRON-	PRP
cord-285778-80baxwgc	357	10	important	important	JJ
cord-285778-80baxwgc	357	11	?	?	.
cord-285778-80baxwgc	358	1	3	3	LS
cord-285778-80baxwgc	358	2	)	)	-RRB-
cord-285778-80baxwgc	359	1	Who	who	WP
cord-285778-80baxwgc	359	2	coined	coin	VBD
cord-285778-80baxwgc	359	3	the	the	DT
cord-285778-80baxwgc	359	4	term	term	NN
cord-285778-80baxwgc	359	5	"	"	``
cord-285778-80baxwgc	359	6	vaccination	vaccination	NN
cord-285778-80baxwgc	359	7	"	"	''
cord-285778-80baxwgc	359	8	and	and	CC
cord-285778-80baxwgc	359	9	on	on	IN
cord-285778-80baxwgc	359	10	what	what	WDT
cord-285778-80baxwgc	359	11	basis	basis	NN
cord-285778-80baxwgc	359	12	?	?	.
cord-285778-80baxwgc	360	1	1	1	LS
cord-285778-80baxwgc	360	2	)	)	-RRB-
cord-285778-80baxwgc	360	3	Can	Can	MD
cord-285778-80baxwgc	360	4	you	-PRON-	PRP
cord-285778-80baxwgc	360	5	define	define	VB
cord-285778-80baxwgc	360	6	these	these	DT
cord-285778-80baxwgc	360	7	terms	term	NNS
cord-285778-80baxwgc	360	8	?	?	.
cord-285778-80baxwgc	361	1	homeostasis	homeostasis	NN
cord-285778-80baxwgc	361	2	,	,	,
cord-285778-80baxwgc	361	3	mucosae	mucosae	NNP
cord-285778-80baxwgc	361	4	,	,	,
cord-285778-80baxwgc	361	5	leukocyte	leukocyte	NN
cord-285778-80baxwgc	361	6	,	,	,
cord-285778-80baxwgc	361	7	cytokine	cytokine	NN
cord-285778-80baxwgc	361	8	,	,	,
cord-285778-80baxwgc	361	9	immunopathic	immunopathic	NNP
cord-285778-80baxwgc	361	10	2	2	CD
cord-285778-80baxwgc	361	11	)	)	-RRB-
cord-285778-80baxwgc	362	1	What	what	WP
cord-285778-80baxwgc	362	2	is	be	VBZ
cord-285778-80baxwgc	362	3	the	the	DT
cord-285778-80baxwgc	362	4	difference	difference	NN
cord-285778-80baxwgc	362	5	between	between	IN
cord-285778-80baxwgc	362	6	infection	infection	NN
cord-285778-80baxwgc	362	7	and	and	CC
cord-285778-80baxwgc	362	8	disease	disease	NN
cord-285778-80baxwgc	362	9	?	?	.
cord-285778-80baxwgc	363	1	3	3	LS
cord-285778-80baxwgc	363	2	)	)	-RRB-
cord-285778-80baxwgc	364	1	What	what	WP
cord-285778-80baxwgc	364	2	is	be	VBZ
cord-285778-80baxwgc	364	3	the	the	DT
cord-285778-80baxwgc	364	4	major	major	JJ
cord-285778-80baxwgc	364	5	difference	difference	NN
cord-285778-80baxwgc	364	6	between	between	IN
cord-285778-80baxwgc	364	7	extracellular	extracellular	JJ
cord-285778-80baxwgc	364	8	and	and	CC
cord-285778-80baxwgc	364	9	intracellular	intracellular	JJ
cord-285778-80baxwgc	364	10	pathogens	pathogen	NNS
cord-285778-80baxwgc	364	11	?	?	.
cord-285778-80baxwgc	365	1	4	4	LS
cord-285778-80baxwgc	365	2	)	)	-RRB-
cord-285778-80baxwgc	365	3	Distinguish	distinguish	VB
cord-285778-80baxwgc	365	4	between	between	IN
cord-285778-80baxwgc	365	5	cell	cell	NN
cord-285778-80baxwgc	365	6	-	-	HYPH
cord-285778-80baxwgc	365	7	mediated	mediate	VBN
cord-285778-80baxwgc	365	8	and	and	CC
cord-285778-80baxwgc	365	9	humoral	humoral	JJ
cord-285778-80baxwgc	365	10	immunity	immunity	NN
cord-285778-80baxwgc	365	11	.	.	.
cord-285778-80baxwgc	366	1	1	1	LS
cord-285778-80baxwgc	366	2	)	)	-RRB-
cord-285778-80baxwgc	366	3	Can	Can	MD
cord-285778-80baxwgc	366	4	you	-PRON-	PRP
cord-285778-80baxwgc	366	5	define	define	VB
cord-285778-80baxwgc	366	6	these	these	DT
cord-285778-80baxwgc	366	7	terms	term	NNS
cord-285778-80baxwgc	366	8	?	?	.
cord-285778-80baxwgc	367	1	senescent	senescent	JJ
cord-285778-80baxwgc	367	2	,	,	,
cord-285778-80baxwgc	367	3	phagocytosis	phagocytosis	NN
cord-285778-80baxwgc	367	4	,	,	,
cord-285778-80baxwgc	367	5	inflammation	inflammation	NN
cord-285778-80baxwgc	367	6	,	,	,
cord-285778-80baxwgc	367	7	PRM	PRM	NNP
cord-285778-80baxwgc	367	8	,	,	,
cord-285778-80baxwgc	367	9	PRR	PRR	NNP
cord-285778-80baxwgc	367	10	,	,	,
cord-285778-80baxwgc	367	11	MHC	MHC	NNP
cord-285778-80baxwgc	367	12	,	,	,
cord-285778-80baxwgc	367	13	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	367	14	,	,	,
cord-285778-80baxwgc	367	15	TCR	TCR	NNP
cord-285778-80baxwgc	367	16	,	,	,
cord-285778-80baxwgc	367	17	BCR	BCR	NNP
cord-285778-80baxwgc	367	18	,	,	,
cord-285778-80baxwgc	367	19	antibody	antibody	NN
cord-285778-80baxwgc	367	20	,	,	,
cord-285778-80baxwgc	367	21	clonal	clonal	JJ
cord-285778-80baxwgc	367	22	selection	selection	NN
cord-285778-80baxwgc	367	23	,	,	,
cord-285778-80baxwgc	367	24	tolerance	tolerance	NN
cord-285778-80baxwgc	367	25	,	,	,
cord-285778-80baxwgc	367	26	self	self	NN
cord-285778-80baxwgc	367	27	antigen	antigen	NN
cord-285778-80baxwgc	367	28	,	,	,
cord-285778-80baxwgc	367	29	immunological	immunological	JJ
cord-285778-80baxwgc	367	30	memory	memory	NN
cord-285778-80baxwgc	367	31	2	2	CD
cord-285778-80baxwgc	367	32	)	)	-RRB-
cord-285778-80baxwgc	368	1	What	what	WP
cord-285778-80baxwgc	368	2	are	be	VBP
cord-285778-80baxwgc	368	3	three	three	CD
cord-285778-80baxwgc	368	4	major	major	JJ
cord-285778-80baxwgc	368	5	differences	difference	NNS
cord-285778-80baxwgc	368	6	between	between	IN
cord-285778-80baxwgc	368	7	innate	innate	JJ
cord-285778-80baxwgc	368	8	and	and	CC
cord-285778-80baxwgc	368	9	adaptive	adaptive	JJ
cord-285778-80baxwgc	368	10	immune	immune	JJ
cord-285778-80baxwgc	368	11	responses	response	NNS
cord-285778-80baxwgc	368	12	?	?	.
cord-285778-80baxwgc	369	1	3	3	LS
cord-285778-80baxwgc	369	2	)	)	-RRB-
cord-285778-80baxwgc	369	3	Distinguish	distinguish	VB
cord-285778-80baxwgc	369	4	between	between	IN
cord-285778-80baxwgc	369	5	DAMPs	damp	NNS
cord-285778-80baxwgc	369	6	and	and	CC
cord-285778-80baxwgc	369	7	PAMPs	pamp	NNS
cord-285778-80baxwgc	369	8	.	.	.
cord-285778-80baxwgc	369	9	 	 	_SP
cord-285778-80baxwgc	370	1	Patient	patient	NN
cord-285778-80baxwgc	370	2	#	#	NN
cord-285778-80baxwgc	370	3	1	1	CD
cord-285778-80baxwgc	370	4	is	be	VBZ
cord-285778-80baxwgc	370	5	having	have	VBG
cord-285778-80baxwgc	370	6	surgery	surgery	NN
cord-285778-80baxwgc	370	7	in	in	IN
cord-285778-80baxwgc	370	8	the	the	DT
cord-285778-80baxwgc	370	9	course	course	NN
cord-285778-80baxwgc	370	10	of	of	IN
cord-285778-80baxwgc	370	11	an	an	DT
cord-285778-80baxwgc	370	12	elective	elective	JJ
cord-285778-80baxwgc	370	13	hip	hip	NN
cord-285778-80baxwgc	370	14	replacement	replacement	NN
cord-285778-80baxwgc	370	15	in	in	IN
cord-285778-80baxwgc	370	16	a	a	DT
cord-285778-80baxwgc	370	17	modern	modern	JJ
cord-285778-80baxwgc	370	18	hospital	hospital	NN
cord-285778-80baxwgc	370	19	.	.	.
cord-285778-80baxwgc	371	1	Patient	patient	NN
cord-285778-80baxwgc	371	2	#	#	$
cord-285778-80baxwgc	371	3	2	2	CD
cord-285778-80baxwgc	371	4	is	be	VBZ
cord-285778-80baxwgc	371	5	not	not	RB
cord-285778-80baxwgc	371	6	so	so	RB
cord-285778-80baxwgc	371	7	lucky	lucky	JJ
cord-285778-80baxwgc	371	8	and	and	CC
cord-285778-80baxwgc	371	9	has	have	VBZ
cord-285778-80baxwgc	371	10	stepped	step	VBN
cord-285778-80baxwgc	371	11	on	on	IN
cord-285778-80baxwgc	371	12	a	a	DT
cord-285778-80baxwgc	371	13	rusty	rusty	JJ
cord-285778-80baxwgc	371	14	nail	nail	NN
cord-285778-80baxwgc	371	15	in	in	IN
cord-285778-80baxwgc	371	16	her	-PRON-	PRP$
cord-285778-80baxwgc	371	17	garden	garden	NN
cord-285778-80baxwgc	371	18	.	.	.
cord-285778-80baxwgc	372	1	What	what	WP
cord-285778-80baxwgc	372	2	sort	sort	NN
cord-285778-80baxwgc	372	3	of	of	RB
cord-285778-80baxwgc	372	4	DAMPs	damp	NNS
cord-285778-80baxwgc	372	5	and/or	and/or	CC
cord-285778-80baxwgc	372	6	PAMPs	pamp	NNS
cord-285778-80baxwgc	372	7	might	may	MD
cord-285778-80baxwgc	372	8	be	be	VB
cord-285778-80baxwgc	372	9	present	present	JJ
cord-285778-80baxwgc	372	10	in	in	IN
cord-285778-80baxwgc	372	11	each	each	DT
cord-285778-80baxwgc	372	12	case	case	NN
cord-285778-80baxwgc	372	13	,	,	,
cord-285778-80baxwgc	372	14	and	and	CC
cord-285778-80baxwgc	372	15	what	what	WDT
cord-285778-80baxwgc	372	16	sorts	sort	NNS
cord-285778-80baxwgc	372	17	of	of	IN
cord-285778-80baxwgc	372	18	immune	immune	JJ
cord-285778-80baxwgc	372	19	responses	response	NNS
cord-285778-80baxwgc	372	20	might	may	MD
cord-285778-80baxwgc	372	21	you	-PRON-	PRP
cord-285778-80baxwgc	372	22	expect	expect	VB
cord-285778-80baxwgc	372	23	to	to	TO
cord-285778-80baxwgc	372	24	find	find	VB
cord-285778-80baxwgc	372	25	in	in	IN
cord-285778-80baxwgc	372	26	these	these	DT
cord-285778-80baxwgc	372	27	patients	patient	NNS
cord-285778-80baxwgc	372	28	?	?	.
cord-285778-80baxwgc	373	1	2	2	LS
cord-285778-80baxwgc	373	2	)	)	-RRB-
cord-285778-80baxwgc	374	1	If	if	IN
cord-285778-80baxwgc	374	2	a	a	DT
cord-285778-80baxwgc	374	3	person	person	NN
cord-285778-80baxwgc	374	4	's	's	POS
cord-285778-80baxwgc	374	5	immune	immune	JJ
cord-285778-80baxwgc	374	6	system	system	NN
cord-285778-80baxwgc	374	7	was	be	VBD
cord-285778-80baxwgc	374	8	unable	unable	JJ
cord-285778-80baxwgc	374	9	to	to	TO
cord-285778-80baxwgc	374	10	produce	produce	VB
cord-285778-80baxwgc	374	11	memory	memory	NN
cord-285778-80baxwgc	374	12	lymphocytes	lymphocyte	NNS
cord-285778-80baxwgc	375	1	Why	why	WRB
cord-285778-80baxwgc	375	2	are	be	VBP
cord-285778-80baxwgc	375	3	B	b	NN
cord-285778-80baxwgc	375	4	lymphocyte	lymphocyte	NN
cord-285778-80baxwgc	375	5	responses	response	NNS
cord-285778-80baxwgc	375	6	usually	usually	RB
cord-285778-80baxwgc	375	7	associated	associate	VBN
cord-285778-80baxwgc	375	8	with	with	IN
cord-285778-80baxwgc	375	9	defense	defense	NN
cord-285778-80baxwgc	375	10	against	against	IN
cord-285778-80baxwgc	375	11	extracellular	extracellular	JJ
cord-285778-80baxwgc	375	12	rather	rather	RB
cord-285778-80baxwgc	375	13	than	than	IN
cord-285778-80baxwgc	375	14	intracellular	intracellular	JJ
cord-285778-80baxwgc	375	15	pathogens	pathogen	NNS
cord-285778-80baxwgc	375	16	?	?	.
cord-285778-80baxwgc	376	1	How	how	WRB
cord-285778-80baxwgc	376	2	might	may	MD
cord-285778-80baxwgc	376	3	they	-PRON-	PRP
cord-285778-80baxwgc	376	4	also	also	RB
cord-285778-80baxwgc	376	5	help	help	VB
cord-285778-80baxwgc	376	6	protect	protect	VB
cord-285778-80baxwgc	376	7	a	a	DT
cord-285778-80baxwgc	376	8	host	host	NN
cord-285778-80baxwgc	376	9	against	against	IN
cord-285778-80baxwgc	376	10	intracellular	intracellular	JJ
cord-285778-80baxwgc	376	11	pathogens	pathogen	NNS
cord-285778-80baxwgc	376	12	?	?	.
cord-285778-80baxwgc	377	1	Can	Can	MD
cord-285778-80baxwgc	377	2	You	-PRON-	PRP
cord-285778-80baxwgc	377	3	Extrapolate	extrapolate	VB
cord-285778-80baxwgc	377	4	?	?	.
cord-285778-80baxwgc	378	1	Some	some	DT
cord-285778-80baxwgc	378	2	Conceptual	conceptual	JJ
cord-285778-80baxwgc	378	3	Questions	question	NNS
cord-285778-80baxwgc	379	1	Would	Would	MD
cord-285778-80baxwgc	379	2	You	-PRON-	PRP
cord-285778-80baxwgc	379	3	Like	like	VB
cord-285778-80baxwgc	379	4	To	to	TO
cord-285778-80baxwgc	379	5	Read	read	VB
cord-285778-80baxwgc	379	6	More	More	JJR
cord-285778-80baxwgc	379	7	?	?	.
cord-285778-80baxwgc	380	1	Overview	overview	NN
cord-285778-80baxwgc	380	2	of	of	IN
cord-285778-80baxwgc	380	3	the	the	DT
cord-285778-80baxwgc	380	4	immune	immune	JJ
cord-285778-80baxwgc	380	5	response	response	NN
cord-285778-80baxwgc	380	6	Regulation	regulation	NN
cord-285778-80baxwgc	380	7	of	of	IN
cord-285778-80baxwgc	380	8	adaptive	adaptive	JJ
cord-285778-80baxwgc	380	9	immunity	immunity	NN
cord-285778-80baxwgc	380	10	by	by	IN
cord-285778-80baxwgc	380	11	the	the	DT
cord-285778-80baxwgc	380	12	innate	innate	JJ
cord-285778-80baxwgc	380	13	immune	immune	JJ
cord-285778-80baxwgc	380	14	system	system	NN
cord-285778-80baxwgc	380	15	Friendly	friendly	JJ
cord-285778-80baxwgc	380	16	and	and	CC
cord-285778-80baxwgc	380	17	dangerous	dangerous	JJ
cord-285778-80baxwgc	380	18	signals	signal	NNS
cord-285778-80baxwgc	380	19	:	:	:
cord-285778-80baxwgc	380	20	Is	be	VBZ
cord-285778-80baxwgc	380	21	the	the	DT
cord-285778-80baxwgc	380	22	tissue	tissue	NN
cord-285778-80baxwgc	380	23	in	in	IN
cord-285778-80baxwgc	380	24	control	control	NN
cord-285778-80baxwgc	380	25	?	?	.
cord-285778-80baxwgc	381	1	Key	key	JJ
cord-285778-80baxwgc	381	2	concepts	concept	NNS
cord-285778-80baxwgc	381	3	in	in	IN
cord-285778-80baxwgc	381	4	immunology	immunology	NN