id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-311331-l7dehit8	Diaz-Arévalo, Diana	Nanoparticle-based vaccines: opportunities and limitations	2020-01-17		.txt	text/plain	5064	266	42	The development of subunit vaccines without risk are considered as an essential need in combination with adequate delivery systems to obtain desired cell and humoral immune responses against infectious diseases. The characteristics of the nanoparticles have allowed targeting desired antigen-presenting cells to improve immunization strategies to induce protection. This chapter focuses on the nanoparticle-based vaccine formulations and the approaches used to realize efficient delivery of vaccines in order to induce host protective immunity against infectious diseases. The combination of the vaccine with the adjuvant or delivery system should be safe, stable, and have the ability to induce long-lived memory B and T cell responses, preferably with a single dose and a maximum of two doses and be free from strict storage requirements [9] . NPs have become an alternative to targeting vaccine delivery to immune cells, improving vaccine efficacy with slow release, easy antigen uptake, and induction of humoral and cellular responses [8] .	./cache/cord-311331-l7dehit8.txt	./txt/cord-311331-l7dehit8.txt