id author title date pages extension mime words sentences flesch summary cache txt cord-298525-hhcfrjrn Hall, Charlotte A. Eyeing up the Future of the Pupillary Light Reflex in Neurodiagnostics 2018-03-13 .txt text/plain 7841 383 37 The pupillary light reflex (PLR) describes the constriction and subsequent dilation of the pupil in response to light as a result of the antagonistic actions of the iris sphincter and dilator muscles. The pupillary light reflex (PLR) describes the constriction and subsequent dilation of the pupil in response to light, which not only serves as a major determination of retinal image quality [1, 2] , but also provides an important metric of autonomic nervous system function [3] . The response latency, maximum constriction and pupil escape, and the corresponding constriction parameters (MCV, MCA and RCA; relative constriction amplitude) are dependent on the actions of the sphincter muscle and on the function of retinal photoreceptors, as well as the time consumed in the afferent and efferent pathway. The ability of pupillometry to detect subtle changes in pupillary reaction even when pupils are constricted has potential clinical significance and may provide a useful tool in the early detection, monitoring and management of brain injuries [89] . ./cache/cord-298525-hhcfrjrn.txt ./txt/cord-298525-hhcfrjrn.txt