id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-257027-q2y7fewk	Lemaire, D.	Coping with genetic diversity: the contribution of pathogen and human genomics to modern vaccinology	2011-10-28		.txt	text/plain	5844	241	33	Additionally, recent advances in immunogenetics and genomics should help in the understanding of the influence of genetic factors on the interindividual and interpopulation variations in immune responses to vaccines, and could be useful for developing new vaccine strategies. The publication of the Haemophilus influenzae genome, the first pathogen to have its complete genome sequence published as a result of an approach to genome analysis using new technologies of high-throughput sequencing (5) , has opened the mind of scientists to a range of new possible approaches to the study of microorganisms and has marked the beginning of a new era in vaccine development: the identification of pathogen candidate antigens based on the knowledge of the genome of the pathogen and on the understanding of microbial biology and host-pathogen interactions, an approach called reverse vaccinology (6) .	./cache/cord-257027-q2y7fewk.txt	./txt/cord-257027-q2y7fewk.txt