id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-016713-pw4f8asc	Goyal, Amit K.	Nanotechnological Approaches for Genetic Immunization	2013-05-24		.txt	text/plain	16034	814	34	The use of nonviral particulate carriers for DNA-based vaccination could provide better and safe delivery of encapsulated genetic material, circumvent the need for muscle involvement and facilitate instead the uptake of the Fig. 4 Schematic representation of immunological response greeted by novel DNA-loaded nanocarrier DNA by APCs. However, transfection of APCs with encapsulated DNA into particulate carrier systems will be dependent upon choice of carrier surface charge, size, and lipid/polymer composition, or presence of other biological [e.g., interleukin 2 and interferon-γ (IFN-γ)]. Modification of lipid/DNA complexes by the polymer poly(D,L-lactic acid) was found to be consistently and significantly more effective than either unmodified liposomal DNA or naked DNA in eliciting transgene-specific immune responses to plasmid-encoded antigen when administered by the s.c. route (Bramwell et al.	./cache/cord-016713-pw4f8asc.txt	./txt/cord-016713-pw4f8asc.txt