id author title date pages extension mime words sentences flesch summary cache txt cord-326163-u8nh8cr3 van Benten, Inesz J. RSV‐induced bronchiolitis but not upper respiratory tract infection is accompanied by an increased nasal IL‐18 response 2003-08-18 .txt text/plain 4379 231 46 The aim of this study was to investigate potential differences in the local nasal immune response between bronchiolitis and upper respiratory tract infection induced by respiratory syncytial virus (RSV). This study investigated whether differences could be observed on the cellular level between the nasal immune responses of infants with RSV-induced bronchiolitis and RSV-induced upper respiratory tract infection. During the acute phase of bronchiolitis as well as during upper respiratory tract infection, there was a marked increase in the numbers of macrophages (CD68positive cells) in nasal brush samples compared with convalescent samples (Fig. 1A) . Most importantly, this study showed a striking difference in cytokine responses between both types of infection, i.e., an increase in the number of IL-18 positive cells in nasal brush samples during bronchiolitis. ./cache/cord-326163-u8nh8cr3.txt ./txt/cord-326163-u8nh8cr3.txt