id author title date pages extension mime words sentences flesch summary cache txt cord-296777-6xz2aslj Oosterhof, L Fatal lower respiratory tract disease with human corona virus NL63 in an adult haematopoietic cell transplant recipient 2009-10-12 .txt text/plain 1195 87 53 title: Fatal lower respiratory tract disease with human corona virus NL63 in an adult haematopoietic cell transplant recipient Community-acquired respiratory viruses are known to account for many cases of interstitial pneumonia as a common complication following allo-haematopoietic cell transplantation (HCT). 7 We present a case of fatal HCoV NL63 pulmonary infection during the late-engraftment phase, 5 months after an allo-HCT with a matched unrelated donor in a patient without active GVHD and receiving only modest immune suppressive treatment. The BAL fluid at day 11 of admission and the final PCR analysis post mortem were negative for HCoV NL63, suggesting that the patient had cleared the virus. Although evaluation for corona virus in symptomatic HCT patients is not routinely performed, we believe it should be considered in the differential diagnoses of respiratory failure or as a possible causative agent before the development of IPS after allo-HCT for haematological disease. ./cache/cord-296777-6xz2aslj.txt ./txt/cord-296777-6xz2aslj.txt