id author title date pages extension mime words sentences flesch summary cache txt cord-286449-ekvzaae2 McManus, Terence E. Respiratory viral infection in exacerbations of COPD 2008-07-30 .txt text/plain 3105 205 49 A respiratory virus was detected in 37% of exacerbations, 12% of stable COPD patients and 12% of non-obstructed smokers, p < 0.0005. Studies using serology and viral culture identified respiratory viruses in 30% of patients during acute exacerbations of COPD. 8 The hypothesis tested in the present study was that acute respiratory viral infection is implicated in the pathogenesis of COPD exacerbations. The detection rate of respiratory viruses during exacerbations of COPD in this study (37%) is comparable to results obtained by Seemungal 9 Lower detection rates may be related to time of sampling as patients presenting to hospital had developed symptoms for a median of 5 days prior to admission. 21 However, several of the patients were seen at different time points during this study and the same virus was not detected by repeat sampling suggesting that those testing positive using the PCR screen were experiencing an acute viral infection. ./cache/cord-286449-ekvzaae2.txt ./txt/cord-286449-ekvzaae2.txt