id author title date pages extension mime words sentences flesch summary cache txt cord-281085-lqniqui0 Nosalova, Gabriela Pharmacological modulation of cough reflex 2006-12-31 .txt text/plain 6991 415 47 As the pathological cough (especially its chronic form) has significant impact on patient's quality of life, observed either in physical activity or psychosocial domain, various treatment attitudes are used for different forms of cough (acute, subacute, chronic, productive, nonproductive, psychogenic, asthma-associated, or painful). The most important defensive reflex of the airways is cough, which, together with the mucociliary transport system, forms the main mechanism for cleaning of the respiratory tract (Korpas and Nosalova, 1991; Chung and Chang, 2002; Belvisi and Geppetti, 2004) . Although respiratory-modulated receptors play an important role in the function of the upper airways, they are not generally viewed as a primary factor in the elicitation of cough reflex. The antitussive activity of these agents is associated with their ability to lower the sensitivity of the cough center to nerve impulses coming from airways receptors (Fox, 1996b) . ./cache/cord-281085-lqniqui0.txt ./txt/cord-281085-lqniqui0.txt