id author title date pages extension mime words sentences flesch summary cache txt cord-264059-jf4j00bp Lee, Chien-Chang Combining Procalcitonin and Rapid Multiplex Respiratory Virus Testing for Antibiotic Stewardship in Older Adult Patients With Severe Acute Respiratory Infection 2019-11-30 .txt text/plain 4611 251 36 3 Initial studies demonstrated that such POC multiplex PCR systems identified previously under-evaluated viral or atypical infections in ED dyspneic patients, and the additional information on rapid respiratory infection testing may also change the physician's antibiotic-prescribing behavior, enabling more timely and appropriate treatment. In this study, we aimed to assess the impact of implementing a diagnostic algorithm that combines rapid respiratory viral surveillance and PCT tests on older patients presenting to the ED with severe acute respiratory illness. This prospective cohort study reports the clinical impact of rapid molecular diagnosis of respiratory pathogens in conjunction with PCT testing on older adult patients presenting to the ED with severe acute respiratory illness. The findings of our study support the use of rapid multiplex PCR respiratory panels in conjunction with the PCT test for early diagnosis of respiratory viral infection and to inform optimizing antibiotic use in older adult patients presenting to the ED with severe acute respiratory illness. ./cache/cord-264059-jf4j00bp.txt ./txt/cord-264059-jf4j00bp.txt