id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-341378-pw60qx7c	Armstrong, John	Sequence and topology of a model intracellular membrane protein, E1 glycoprotein, from a coronavirus	1984		.txt	text/plain	1578	88	55	In combination with a previous study of its assembly into the endoplasmic reticulum membrane(9), the sequence reveals several unusual features of the protein which may be related to its intracellular localization. In the eukaryotic cell, both secreted and plasma membrane proteins are synthesized at the endoplasmic reticulum, then transported, via the Golgi complex, to the ceU surface 1 -4. Here we present the primary structure of the protein, determined by analysis of eDNA clones prepared from viral mRNA. In combination with a previous stu'!} of its assembly into the endoplasmic reticulum membrane , the sequence reveals several unusual features of the protein which may be related to its intracellular localization. Thus, the El glycoprotein is potentially a convenient model for studying those features of a membrane protein that determine its arrest at a particular destination on the membrane transport pathway.	./cache/cord-341378-pw60qx7c.txt	./txt/cord-341378-pw60qx7c.txt