id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-333757-h12aozg2	Modis, Yorgo	Class II Fusion Proteins	2013-07-10		.txt	text/plain	6790	393	51	Furthermore, all available crystal structures of class II fusion proteins lack the 'stem' region, 43 a 30-55 amino acid linker between Domain III and the C-terminal transmembrane anchor (Figs. The three-dimensional structures of four class II fusion proteins in their postfusion states 29,55,56,94 reveal striking differences from the prefusion forms (Fig. 3) , and suggest a 13 and B) two SFV E1 12 molecules in the prefusion conformation as found on the viral surface, viewed perpendicular to the viral membrane. 29, 55 A deep channel extends from the C-terminus of the crystallized fragment along the intersubunit contact between domains II to the fusion loops, in both the dengue and Semliki Forest virus postfusion trimer structures. The recently determined crystal structures of class II fusion proteins in pre 10,12-14 and postfusion 29, 55, 56 conformations offer the first direct views of fusion anchors-in this case, the fusion loops-as they insert into a target membrane (Fig. 4) .	./cache/cord-333757-h12aozg2.txt	./txt/cord-333757-h12aozg2.txt