id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-319809-33i6lzjd	Drew, Elliot D.	Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity	2020-07-01		.txt	text/plain	4573	210	57	title: Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity RESULTS: Our analyses of this structure have revealed a key potentially druggable pocket where it might be viable to bind pharmaceutical agents to inhibit its ability to infect human cells. The results from the three methods, Autodock vina [12] , Smina [13] and Ledock [14] , were used to generate a list of 4358 poses of commercially-available drugs capable of binding into this Covid-19 spike protein pocket. This study provides a suggested list of pharmaceutical agents, identifying some of them as being from related structure families, that are available on the market and have been sanctioned for use in humans that have been shown to be capable of binding into a druggable pocket in the spike protein of Covid-19.	./cache/cord-319809-33i6lzjd.txt	./txt/cord-319809-33i6lzjd.txt